UA81229C2 - Use of [6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1h-pyrrolizine-5-yl]-acetic acid in the treatment of articular cartilage or subchondral bone degeneration - Google Patents

Use of [6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1h-pyrrolizine-5-yl]-acetic acid in the treatment of articular cartilage or subchondral bone degeneration Download PDF

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Publication number
UA81229C2
UA81229C2 UA2004032301A UA2004032301A UA81229C2 UA 81229 C2 UA81229 C2 UA 81229C2 UA 2004032301 A UA2004032301 A UA 2004032301A UA 2004032301 A UA2004032301 A UA 2004032301A UA 81229 C2 UA81229 C2 UA 81229C2
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UA
Ukraine
Prior art keywords
cartilage
dogs
cells
samples
synovial membrane
Prior art date
Application number
UA2004032301A
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English (en)
Ukrainian (uk)
Original Assignee
Merckle Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merckle Gmbh filed Critical Merckle Gmbh
Priority claimed from PCT/EP2002/009658 external-priority patent/WO2003020267A1/fr
Publication of UA81229C2 publication Critical patent/UA81229C2/uk

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
UA2004032301A 2001-08-30 2002-08-29 Use of [6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1h-pyrrolizine-5-yl]-acetic acid in the treatment of articular cartilage or subchondral bone degeneration UA81229C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002356099A CA2356099A1 (fr) 2001-08-30 2001-08-30 Utilisation de composes de pyrolle annele dans le traitement du cartilage articulaire ou de la degenerescence des os sous- chondraux
PCT/EP2002/009658 WO2003020267A1 (fr) 2001-08-30 2002-08-29 Utilisation de composes de pyrrole anneles dans le traitement de la degenerescence d'un cartilage articulaire ou d'un os sous-chondral

Publications (1)

Publication Number Publication Date
UA81229C2 true UA81229C2 (en) 2007-12-25

Family

ID=4169830

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2004032301A UA81229C2 (en) 2001-08-30 2002-08-29 Use of [6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1h-pyrrolizine-5-yl]-acetic acid in the treatment of articular cartilage or subchondral bone degeneration

Country Status (3)

Country Link
CA (1) CA2356099A1 (fr)
UA (1) UA81229C2 (fr)
ZA (1) ZA200402440B (fr)

Also Published As

Publication number Publication date
CA2356099A1 (fr) 2003-02-28
ZA200402440B (en) 2004-10-07

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