UA79659C2 - Substituted alkylamidopiperidines - Google Patents
Substituted alkylamidopiperidines Download PDFInfo
- Publication number
- UA79659C2 UA79659C2 UAA200506356A UA2005006356A UA79659C2 UA 79659 C2 UA79659 C2 UA 79659C2 UA A200506356 A UAA200506356 A UA A200506356A UA 2005006356 A UA2005006356 A UA 2005006356A UA 79659 C2 UA79659 C2 UA 79659C2
- Authority
- UA
- Ukraine
- Prior art keywords
- piperidinyl
- alkyl
- straight
- phenyl
- compound according
- Prior art date
Links
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- 229960001005 tuberculin Drugs 0.000 description 1
- 238000007492 two-way ANOVA Methods 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 125000001493 tyrosinyl group Chemical group [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
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- 238000003828 vacuum filtration Methods 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
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Classifications
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- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
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- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
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- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
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US7105544B2 (en) * | 2001-07-05 | 2006-09-12 | Synaptic Pharmaceutical Corporation | Substituted alkyl amido piperidines |
WO2003099266A2 (en) * | 2002-05-23 | 2003-12-04 | Abbott Laboratories | Acetamides and benzamides that are useful in treating sexual dysfunction |
US20040029887A1 (en) * | 2002-05-23 | 2004-02-12 | Bhatia Pramila A. | Acetamides and benzamides that are useful in treating sexual dysfunction |
US20060009461A1 (en) * | 2002-05-23 | 2006-01-12 | Bhatia Pramila A | Acetamides and benzamides that are useful in treating sexual dysfunction |
CA2515717A1 (en) * | 2003-02-10 | 2004-08-19 | Banyu Pharmaceutical Co., Ltd. | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient |
US7783672B2 (en) * | 2003-04-09 | 2010-08-24 | Microsoft Corporation | Support mechanisms for improved group policy management user interface |
EP2308839B1 (en) * | 2005-04-20 | 2017-03-01 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compounds |
MX2008009581A (es) * | 2006-01-27 | 2009-01-07 | Fibrogen Inc | Compuestos de cianoisoquinolina que estabilizan el factor inducible hipoxia (fih). |
WO2009041567A1 (ja) * | 2007-09-27 | 2009-04-02 | Banyu Pharmaceutical Co., Ltd. | メラニン凝集ホルモン受容体拮抗作用を有するジアリールケチミン誘導体 |
US9206143B2 (en) * | 2008-03-19 | 2015-12-08 | Aurimmed Pharma, Inc. | Compounds advantageous in the treatment of central nervous system diseases and disorders |
US10793515B2 (en) | 2008-03-19 | 2020-10-06 | Aurimmed Pharma, Inc. | Compounds advantageous in the treatment of central nervous system diseases and disorders |
CN101981025A (zh) * | 2008-03-28 | 2011-02-23 | 万有制药株式会社 | 具有黑色素浓缩激素受体拮抗作用的二芳基甲基酰胺衍生物 |
WO2010050456A1 (ja) * | 2008-10-30 | 2010-05-06 | 萬有製薬株式会社 | ジ又はトリアリールメチル構造を有するピペリジン化合物 |
ES2700527T3 (es) | 2013-01-21 | 2019-02-18 | Univ Osaka | Compuesto de fenoxialquilamina |
WO2014195276A1 (en) * | 2013-06-07 | 2014-12-11 | Bayer Pharma Aktiengesellschaft | Substituted triazolopyridines having activity as mps-1 inhibitors |
CA2950259C (en) * | 2014-05-28 | 2022-08-23 | Astellas Pharma Inc. | Pyridine derivative for the treatment of nocturia |
CN105279394B (zh) * | 2015-10-13 | 2017-12-26 | 山西农业大学 | 用于神经肽受体筛选的方法 |
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---|---|---|---|---|
US5459151A (en) | 1993-04-30 | 1995-10-17 | American Home Products Corporation | N-acyl substituted phenyl piperidines as bronchodilators and antiinflammatory agents |
SE9803518D0 (sv) | 1998-10-15 | 1998-10-15 | Astra Pharma Prod | Novel compounds |
US20030082623A1 (en) | 1998-12-31 | 2003-05-01 | Beth Borowsky | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof |
GB9912413D0 (en) | 1999-05-28 | 1999-07-28 | Pfizer Ltd | Compounds useful in therapy |
US20040038855A1 (en) * | 1999-12-30 | 2004-02-26 | Salon John A. | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof |
EP1299362A4 (en) | 2000-07-05 | 2004-11-03 | Synaptic Pharma Corp | SELECTIVE RECEPTOR ANTAGONISTS OF MELANINE CONCENTRATING HORMON-1 (MCH1) AND THEIR USE |
US6720324B2 (en) * | 2000-07-05 | 2004-04-13 | Synaptic Pharmaceutical Corporation | Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof |
AU7320701A (en) | 2000-07-05 | 2002-01-14 | Synaptic Pharmaceutical Corporation | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof |
FR2815032B1 (fr) | 2000-10-10 | 2003-08-08 | Pf Medicament | Nouveaux derives d'aminophenyle piperazine ou d'amino phenyle piperide inhibiteurs de proteines prenyl transferase ainsi que leurs preparations |
US7105544B2 (en) * | 2001-07-05 | 2006-09-12 | Synaptic Pharmaceutical Corporation | Substituted alkyl amido piperidines |
CN1671386A (zh) | 2001-07-05 | 2005-09-21 | H·隆德贝克有限公司 | 作为mch选择性拮抗剂的取代苯胺基哌啶 |
US6727264B1 (en) | 2001-07-05 | 2004-04-27 | Synaptic Pharmaceutical Corporation | Substituted anilinic piperidines as MCH selective antagonists |
US7199135B2 (en) * | 2001-07-05 | 2007-04-03 | H. Lundbeck A/S | Substituted alkyl amido piperidines |
UA77814C2 (en) | 2002-07-03 | 2007-01-15 | Lundbeck & Co As H | Spirocyclic piperidines as antagonists of mch1 and use thereof |
UA77536C2 (en) | 2002-07-03 | 2006-12-15 | Lundbeck & Co As H | Secondary aminoaniline piperidines as mch1 antagonists and their use |
AU2003299791A1 (en) | 2002-12-20 | 2004-07-22 | Bayer Pharmaceuticals Corporation | Substituted 3,5-dihydro-4h-imidazol-4-ones for the treatment of obesity |
-
2003
- 2003-01-14 US US10/345,063 patent/US7105544B2/en not_active Expired - Fee Related
-
2004
- 2004-01-06 JP JP2006500796A patent/JP2006515618A/ja not_active Withdrawn
- 2004-01-06 EP EP04700366A patent/EP1590326A4/en not_active Withdrawn
- 2004-01-06 US US10/541,991 patent/US20060217418A1/en not_active Abandoned
- 2004-01-06 BR BR0406725-8A patent/BRPI0406725A/pt not_active IP Right Cessation
- 2004-01-06 MX MXPA05006956A patent/MXPA05006956A/es not_active Application Discontinuation
- 2004-01-06 NZ NZ540366A patent/NZ540366A/en unknown
- 2004-01-06 CA CA002509456A patent/CA2509456A1/en not_active Abandoned
- 2004-01-06 PL PL378394A patent/PL378394A1/pl not_active Application Discontinuation
- 2004-01-06 AU AU2004206794A patent/AU2004206794A1/en not_active Abandoned
- 2004-01-06 KR KR1020057013094A patent/KR20060002747A/ko not_active Application Discontinuation
- 2004-01-06 EA EA200501122A patent/EA009818B1/ru not_active IP Right Cessation
- 2004-01-06 CN CNA2004800020809A patent/CN1735595A/zh active Pending
- 2004-01-06 WO PCT/US2004/000175 patent/WO2004064764A2/en active Application Filing
- 2004-01-12 AR ARP040100069A patent/AR042839A1/es not_active Application Discontinuation
- 2004-01-16 CL CL200400064A patent/CL2004000064A1/es unknown
- 2004-06-01 UA UAA200506356A patent/UA79659C2/uk unknown
-
2005
- 2005-05-23 IS IS7860A patent/IS7860A/is unknown
- 2005-05-24 ZA ZA200504218A patent/ZA200504218B/en unknown
- 2005-07-11 IL IL169637A patent/IL169637A0/en unknown
- 2005-07-21 CO CO05072012A patent/CO5590901A2/es not_active Application Discontinuation
- 2005-08-15 NO NO20053838A patent/NO20053838L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CL2004000064A1 (es) | 2005-03-18 |
PL378394A1 (pl) | 2006-04-03 |
NZ540366A (en) | 2008-01-31 |
AU2004206794A1 (en) | 2004-08-05 |
US20040073036A1 (en) | 2004-04-15 |
NO20053838L (no) | 2005-08-15 |
WO2004064764A3 (en) | 2005-01-13 |
IL169637A0 (en) | 2007-07-04 |
CA2509456A1 (en) | 2004-08-05 |
IS7860A (is) | 2005-05-23 |
EA200501122A1 (ru) | 2006-02-24 |
CN1735595A (zh) | 2006-02-15 |
WO2004064764A2 (en) | 2004-08-05 |
EP1590326A2 (en) | 2005-11-02 |
US20060217418A1 (en) | 2006-09-28 |
US7105544B2 (en) | 2006-09-12 |
ZA200504218B (en) | 2006-07-26 |
JP2006515618A (ja) | 2006-06-01 |
EP1590326A4 (en) | 2008-04-30 |
CO5590901A2 (es) | 2005-12-30 |
BRPI0406725A (pt) | 2005-12-20 |
KR20060002747A (ko) | 2006-01-09 |
MXPA05006956A (es) | 2005-10-26 |
AR042839A1 (es) | 2005-07-06 |
US20060041139A9 (en) | 2006-02-23 |
EA009818B1 (ru) | 2008-04-28 |
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