UA75335C2 - A method for water disinfection and a composition for realizing the same - Google Patents

Abstract

The invention relates to the field of medicine and sanitation and can be used for purification and disinfection of industrial, potable, recreation and other waters. The water is processed with the composition based on guanidine polymers, which includes in addition a potentiating reagent-oxidant which strengthens algicide, fungicide and bactericidal properties of biocide guanidine polymer. The composition has high disinfection properties and profitability. The use of applied method and composition will allow to provide a reliable sanitary-technical functioning of such water objects, as swimming and decorative pools, cooling towers, boiler-rooms, fountains, tanks for water storage, circulatingsystems of water supply and so on.

Description

compounds - persulfates, percarbonates, perborates 10. The composition according to item 7, which differs in that it contains alkali and alkaline earth metals, other compounds, as a potentiating reagent-oxidizer capable of releasing hydrogen peroxide or oxygen when sodium perborate. soluble in water, or their mixtures. 11. The composition according to claim 7, which is characterized in that 9. The composition according to claim 7, which is characterized in that it contains sodium perborate in the form of pills. as a potentiating reagent-oxidizer, it contains a compound in the form of a gas, liquid, or solid.

The invention relates to the field of medicine and medicine, and not to undesirable taste. nitaria and can be used for purification and de- Guanidine compounds, including polymeric gas- contamination of water in open and closed containers, anidines, are well known and widely used in various areas, especially water that is heated and aerated. Many applications have been created on their basis, including in swimming pools, fountains, cooling towers, boiling antiseptics, disinfectants, inhibitors, water towers, corrosion storage containers, contact lens cleaners, etc. etc. of water, tankers, circulating water in systems - see, for example, (Lulle I., Zh. et al.

The traditional method of water treatment with the aim of its swelling activity. - Author's certificate of disinfection from pathogenic microorganisms, including in the USSR Me944290A, IPC? 0 со07с129/12; including fungi and algae, there is water chlorination. Ab1K31/155, publication in B.IM. Me11, 1986) |Z1;

A typical reagent for chlorination of water in the above (Ufimtsev A.V. et al. Application of polyhexamethysed containers and systems - calcium hypochlorite, lenguanidine phosphate as a corrosion inhibitor, see, for example, (Methodical instructions on prosody. - Russian patent Me VO - 94025102, IPC? for preventive disinfection in sports S2gZ3E11/00, 20.05.961 |4); contact - 03.80 Me28-2/6. - M., 19801 11. tny lenses. - Patent of Ukraine Me OAD-17214A, IPC?

However, the harm that chlorine and its compounds cause - C1101/825; C1103/48, publication 10/31/97, Bull. give to the environment and consume - Mo BI. cham, accelerated the search and use of other re- A well-known method of water disinfection, med- icals for water treatment. them and swimming pools, which in total o3-

The disadvantage of the well-known method of disinfecting water and the result that is achieved is technical water is that during such treatment of water with a solution closest to the disinfectant we have declared, namely chlorine, is released into the scientific - see, for example, (Efimov K. M. and others, the method is a wasteful environment, which causes great damage to the health and swimming waters, not only to the surrounding environment, but also to the swimming pool. - Patent of Russia Me VO-2145307, IPC" living organisms. СО2Е1/50; Аб112/16 ,2/18; A0O1M47/44, publication

An alternative to chlorine is especially needed for 10.02.2000 - prototypes/|b). water treatment, which in the process of their use is aerated. In the mentioned method, the water in the pool is disinfected, for example, water in pools, cooling towers, by treating it with PGMG phosphate, phosphate cooling towers, industrial boilers, volumes of polyoxyalkyleneguanidine or co-decorative phosphate fountains, etc. First of all, these are PGMG polymers with higher monoamines. Due to the high volatility of chlorine, which in this case, the water of the pool with flowing or water recirculation evaporates and "flies", therefore the water is treated with a water exchange scheme, which requires a constant introduction of chlorine to maintain its effective concentration by polymeric guanidines working concentration in water for it is 0.5-1.5mg/l, and pool water with recirculation reliable disinfection. the water exchange scheme, in addition, is passed through

Special difficulties arise when using a layer of clinoptinolite treated with guanidine and chlorine in pools, including swimming pools, with polymers up to their content of 1-2 wt.95. This treatment, where the water has an elevated temperature Trob-27-2976, meets the sanitary requirements for swimming pools, which contributes to the significant evaporation of chlorine from the water of swimming pools and is quite effective. which, at the same time, concentrates in the breathing zone. However, under certain conditions (elevated temperature, water aeration, high lighting, etc.)

An alternative to the chlorination of pool water and the algicidal, fungicidal and bactericidal effect of guanine and other waters is the use of polymeric guanidine dinopolymers in the specified concentrations of impurities, for example, polyhexamethyleneguanidine (in the state and under such conditions, the growth of the following text is significantly enhanced - PGMG) - see for example algae, fungi and bacteria. Especially stable

I.F. Kuznetsov et al. The method of disinfection is the symbiosis of fungi and algae. This causes unusual pools. Patent of Russia Me VI - 1799600, necessity of emergency release from water ba-

IPC? Ab112/16, 07.03.1993, publication in B.I. Me9| sein, fountain or water storage tank,

II. increased mechanical cleaning of the walls from biological

The advantages of the mentioned alternative method with subsequent strong disinfection are that it is completely chlorine-free and does not show any disinfectants. But such a procedure gives a temporary irritating effect, the treated water has neither a negative effect, because after some time the growth of biota resumes. frames for the specified purposes are polyhexamethyleneguani-

To prevent biofouling when using guanidine chloride and polyhexamethyleneguanidine phosphate, cheap guanidine polymers, it is necessary to use a reagent that enhances the biocidal (algicidal, fungicidal, bactericidal) properties of guanidine Polyhexamethyleneguanidine is not volatile, non-degradable polymer. dissolves in water, has no color, does not give water an odor

We have established that as enhancers and taste, does not have an irritating effect, is not toxic, (potentiating) reagents can act unstable and safe when used, transportable amounts of compounds that have oxidizing properties during handling and storage. solids or are released in the aqueous environment. Aquaton is produced in the form of concentrated atomic oxygen, free halogen or peroxide aqueous solution containing 3095 active hydrogen sulfide. As it is known, oxidants themselves have some substances (PGMG). When used for non-biocidal properties. However, such properties, the concentration of the water in the swimming pool is strongly algicidal, they show enough guanidine polymer in the water should be in high concentrations, namely 3.0-15.Omg/l, which is not 0.5-1.5mg/ l. At the concentration of guanidine poly- is always acceptable for practical use. mayor in water at a level below 0.5mg/l, water does not

We have established that the introduction of oxidizing substances that emit peroxide values into the water that is treated meets the sanitary requirements for microbiological agents. Maintaining the concentration of hydrogen guanine, free halogen or oxygen in the concentration of the acid polymer in water at a level that exceeds 0.05-1.0 mg/l, that is, at those concentrations at 1.5 mg/l, is not desirable, because price increases significantly, which are practically not manifested or are weakly created. their personal biocidal properties are manifested. Then the water is treated with a strengthening (potentiating) reagent. The concentration of the enhancer has a significant biocidal effect. This allows the reagent in the water to be 0.05-1.Omg/l. effectively suppress not only the growth of microbes, but also as potentiating reagents there can be algae and fungi in the water and on the walls of the pools, the following compounds are used, which are chosen from a number of cooling towers, pipes, fountains, etc. which consists of hydrogen peroxide, ozone, chlorine

The claimed method is carried out as follows: (in the concentrations in which chlorine is nominally used for the specified purposes, it does not show significant harm

Water in a swimming pool, water tower, fountain or di), calcium hypochlorite and other chlorine compounds, which are treated with a guanidine solution in another system, release free chlorine, bromine, iodine and their polymer in the water, which is used as aqueous solutions that are released in water free halogen, polyhexamethyleneguanidine of common peroxygen compounds (persalts) - persulfates, percarmol: bonates, perborates and their mixtures.

Persalts of alkaline and alkaline earth metals, such as sodium or potassium perborate, are preferred. These perborates of sodium or potassium have

MN x K, the following advantages: they are available, inexpensive and have low toxicity to mammals. where: Ki is the acid residue of a mineral or Potentiating reagent depending on its organic acid; of nature can be used in a gaseous p-5-50 form (chlorine, bromine, ozone), in the form of an aqueous solution (hydrogen peroxide, solutions of persalts and polyhexamethyleneguanidine copolymer compounds with higher halogens), in the form of a powder or in the form monoamine pills of the general formula: (persols, compounds of chlorine, bromine, iodine).

When using persoles, the advantage of fo-

N- Kk -I-MN-S-MNASNO)v a MN-S-MN- K.-N rma pills, because pills are convenient to use

Its contents and the rate of their dissolution are easily controlled.

Mn'n, MN"; you.

The rate of dissolution of pills, among other things, is determined by their density, which depends on pressure

Ag - acidic residue of mineral or organic during their production by pressing. In addition, nocturnal acid; And the use of polyethylene glycol as a binder

VE. - |«СНо)з--О-(СН2) 2-04 СН) (СН)з-Ж which agent allows to significantly expand the range of т-30-40. or: polyoxyalkyleneguanidine in general - dissolution rates. of the formula: Rapid dissolution of pills is necessary to create shock doses of hydrogen peroxide in critical situations with the growth of biota.

Н In conditions where the growth of algae and fungi is

МЙ x Ез is changed (in swimming pools - this is usually the winter period), the dissolution rate of the pills can be moderate.

Vz - an acid residue of mineral or organic sodium perborate pills are safe in case of final acid; non-toxic, odorless, tasteless or k-4-50. unpleasant fumes.

The most available guanidine polymers. To confirm the existence of a synergistic disinfecting effect of enhancing the biocidal properties of the guanidine polymer in the presence of oxidizing compounds, we present the experimentally determined minimum bactericidal concentrations of guanidine polymer solutions, oxidizing compounds, and their mixtures. . Minimum Bacteri- The ratio of com- What cidal concentration (hereinafter referred to as MBEC) is and ponents in the solution Minimum Bac- the minimum concentration of the drug, which completely Me prik-| (dg mg reagent), wt. | Terricidal kills one or another microorganism and is a quantitative measure of the concentration of the mixture, a characteristic of the biocidal activity of the drugs in μg/ml in relation to one or another microorganism. 35213100 009

The smaller the MBEC value, the higher the biocidal 3817081 05100835 vkyrn l prep! 19 |06| 04 | 006

The minimum bactericidal concentration of water; of solutions of guanidine polymers, compounds 04| 06 | 005 ( oxidants and their mixtures were determined by the method of serial 21 | 02 | 08 | 029 dilutions. E-soy obtained from the Museum of Living Cultures was used as a test microorganism.

Institute of Epidemiology and Infectious Diseases named after Data analysis; given in tables 1-4 according to

L.V. Gromashevsky Academy of Medical Sciences of Ukraine. says that MBK compositions of guanidine polymer

The obtained experimental data, listed in Tables 1-4, are not shown for oxidizing compounds (potentiating reagents). the result of the additive addition of MBK of individual components, and has an extreme dependence on their content (ratio). As can be seen from Tables 2-5,

Table 1 for each oxidizing compound is characterized by its optimal ratio with guanidine poly-

The ratio of compo-SCI mer, which shows a significant decrease in the bactericidal MC, which indicates an increase in biocidal activity. oeagent), wt. parts of the I ryklad, for sodium perborate with guanidine lada Hypochlorite na- | concentration with a polymer, the optimum ratio of the mixture is 4:11, μg/ml (example 15), for hydrogen peroxide - 3:1 (example

ZY 0003331 009 20), for sodium hypochlorite and chloramine -1:1 (examples C and 8, respectively). Predict this optimally

With 0.5 0.5 0.023 visible and can only be determined experimentally for each compound- | 0 | 1 | 021 | oxidizer separately. That is, it is nothing more than an inventive step, and its meaning is characterized by the inventive level.

Table 2. The mechanism of the synergistic effect, that is, the effect of strengthening the biocidal properties of guanidino-

The ratio of compo- | The minimum value of polymers lies, in our opinion, in the fact that

Me pri- | nents in the solution (PGMG k| bactericidal simultaneous presence in the solution of oxidizing compounds of the reagent), wt. concentration of particles and the guanidine polymer leads to a change in the mixture, μg/ml of the mechanism of biocidal action of the guanidine polymer by 6 | 1 | 0 | 009 | microorganisms due to the formation of a guanidine polymer complex - an oxidizing compound. On the basis of 8105 | 05 | 06045. | The existence of the complex is also indicated by the fact that the most 91025 | 075 | 067..M.B.. higher biocidal activity of the solutions is manifested 30010011 1081 "| at certain ratios of the guanidine polymer and the oxidizing compound.

Complexes forming guanidine polymers

In our opinion, compounds with oxidizing compounds interact more effectively with cell membranes

The ratio of com- microorganisms, leading to their faster death in the solution Minimal buckling at lower concentrations of guanidine poly-

Mo prik- | PGMG x" reagent), wt. | terricidal con- meru. In this, perhaps, lies the mechanism of support: p. the potentiating effect of the potentiating reagent on the biocidal particles, concentration of the mixture, . . and properties of guanidine polymers with creation

Perborate na-mcg/ml. synergistic disinfecting side effect.

ZY 001005 The invention is illustrated by the following examples.

Example 1 (control). 712 |08| 5 sh 02 | oh | Model pool with a volume of 50 l with transparent 13 |06| 04 | 008 | the walls were filled with tap water. Water 14 |04| 06 | 006 | were treated with the disinfectant PGMG at a concentration of |02| 08 | 003 | 1.0 Ω/l. The concentration of PGMG was maintained at the level

0.5-1.O0mg/l by conducting an analytical point was treated with gaseous chlorine, maintained every day and, if necessary, carrying out the concentration of free chlorine at the level of dila, correction of the concentration of PGMG by an estimated 0.05-0.3mg/l (the optimal value is the amount of working solution of PHMG. With the help of 0.1-0.2mg/l). Algae growth was not detected (0 pump water circulated through a sand filter and points). aerated The temperature of the water in the pool was maintained at the level of Trob-27-2970. The pool was illuminated - a swimming pool with a volume of 350 m3 of water after sunset during daylight hours. Bio-sanitary treatment was filled with tap water, and the walls of the pool were evaluated by 4-point water. The water was treated with the PHMG disinfectant to a scale from 0 to 3: creating the concentration of the guanidine polymer

O - there is no visible growth of biota on the walls of the res- 1mg/l. rvoir; In the bath of the pool, evenly along the lower edge - 1 - a small visible growth; a tablet was attached to the meter once a week - 2 - average visible growth; of sodium perborate, which were manufactured in

C - strong visible growth. weights specified in example 3. Total mass

After the continuous operation of the model pool, the tablets were 1.4 kg per 350 m3 of water. Well, over the course of weeks, green, brown-green algae and slime appeared on the walls of the pool, which indicated the symbiosis of algae, bacteria and 2001. including. The water temperature of the coli-fungi pool. Growth was assessed in Z points. was in the interval Trob-25-292С. Concentration

Experiments were carried out in the summer months, 2000 PGMG was maintained at the level of 0.5-1.0mg/l. by year carrying out analytical control every day and in

Example 2. if necessary, correction of concentration

The conditions of example 1 were followed, but the water added to the PGMG in the calculated working amount was treated with hydrogen peroxide, maintaining the PGMG solution. The concentration was periodically monitored at the level of 0.05-1.O0 mg/l. During the 3 months of the epidemiological safety of the pool water for the following months of the experiment (June-August 2001), sanitary and microbiological indicators: no growth of hydrogen - Total microbial number was visually detected; fungi or fungi (0 points). - Group of Escherichia coli (coli index);

Example 3. - Blue fever bacillus.

The conditions of example 1 were followed, but the water was added. Physico-chemical indicators were regularly determined, the water was treated with sodium perborate, placing the water: once a week in the water, a tablet containing 0.2 g - Color; sodium perborate. - Turbidity;

The tablet was made by pressing - pH value; of sodium perborate powder at the pressure value - General hardness of water; 5 kg/sme. When dissolved, the tablet ensured the presence or absence of biofouling and the concentration of hydrogen peroxide in the pool water was measured visually according to a 4-point system (see levels 0.08--0.10mg/l. During the 3-month experi- Example 1). The study showed that no growth of algae and fungi was detected during the entire experimental period, biota growth was absent (0 points). (0 points).

Example 4. Research data on analytical and microbiological

The conditions of example 1 were met, but water was added - the parameters of the pool water are summarized in Table 5.

Table 5 is no more

Turbidity m/dm' | 15 )/04)|06)|05)|08)|07|70 080910

Meaning of N. | 65-85 | 71 | 78 | 70 | 76 | 69 | 79 | 72 | 75 | 78 mg-eq/dm oTotal microbial count | With | With | 10 | 6 | 11 | 4 | 7 | 1 | 9 | 28

The analysis of the data in this table shows that over time, the physical and chemical properties of water, especially the sanitary and microbiological studies shown in the table, indicate that the processing of basins has met the requirements for the declared method did not lead to side waters of swimming pools (see table). One - no harmful effects, and the water meets regulatory requirements. that way.

The claimed method of water treatment with the use of a potentiating (potentiating) reagent Example 8 The conditions of example 6 were fulfilled, but ozone, ("shock") doses of the potentiating reagent in several processed water to its concentration in water, which is 2-3 times higher than the usual norm - 0О,О5mg/l. The results were positive, as in the burning dosage. This method can be recommended for example 6. for tanks and pools that are heavily overgrown with algae or very neglected, with the conditions of example 6 fulfilled, but as a purpose of their rehabilitation. hypochlorous acid was used as a tensing reagent

Example 6 calcium rite, which was used to treat water to concentration

A swimming pool with a volume of 350 m3 of water after free chlorine in the water at the level of 2.Omg/l. sanitary treatment was filled with tap water The results were positive, as in the case of water. The water was treated with the PGMG disinfectant to Example 6. Creating a concentration of guanidine polymer Example 10 of 1 mg/l. The pool was operated as intended. Fulfilled the conditions of example b, but as a

Regularly (1 time a day) the concentration reagent was used, persul- concentration of guanidine polymer with analytical sodium phate, which was used to treat water to concentration method and, in necessary cases, hydrogen peroxide in water at the level of 3.Omg/l was monitored. treatment with a working polymer solution. During the Results were positive, as in the case of the entire experiment, the concentration of guanidine example 6. polymer ranged from 0.5 to 1.0 mg/l. Thus, the declared method of water treatment

The tests were conducted in the summer months with 2000 biocidal guanidine polymers and potencies of the year (June-July). The temperature of the water maintained by the agents is based on the installed water level at the level of Trob-26-292С. to the synergistic effect of enhancing biocidal (algal

After 3 weeks of operation of the pool in the corners and cidic, fungicidal and bactericidal) typically on the bottom of the pool, primarily on the cement seams of the guanidine polymer. The use of a biofouled method will allow to ensure a reliable green color, slippery to the touch, which will indicate the sanitary and technical functioning of such water shafts for the symbiosis of algae and fungi in objects such as swimming and decorative pools. , play- (From points). pits, boiler rooms, fountains, storage tanks

At the end of the day, dosing of water, reversible water supply systems and (4 kg) of sodium perborate in the form of powder, calculations, etc., were introduced into the pool water. one in 40 liters of water. The solution is evenly distributed around the perimeter. Sources of information that were taken into account: ru of the pool was poured into the water and with the help of water jets 1. Methodical instructions for carrying out the profin was stirred for 15 minutes. This ensured the lactic disinfection in sports swimming, and the concentration of hydrogen peroxide in the water was at their level in the pools of the Ministry of Health of the USSR from March 31, 1980. Mo28-2/6. -

Zmg/l The next day, browning was observed in M., 1980 111; adults, their coagulation and sedimentation at the bottom of pools - 2. O.F. Kuznetsov et al. Method of disinfection in the form of brown flakes that were removed from treatment pools. - Patent of Russia Me VO - in the usual way with the help of a water pump. 1799600, IPC? Ab112/16, 07.03.1993, publication in

Determination of hydrogen peroxide concentration in B.I. me9 (2. the next day in the morning, the pool water showed a high level of polyhexamethylenegua phosphate - 0.08 mg/l, which allowed the pool to be actively used. The next step - Ator certificate of the USSR Me 5) - processing can be carried out as necessary. 944290A, IPC" C07C129/12; AbIKZ1/155, public

Example 7. cation in B.I. Me11, 1986 ZI;

We fulfilled the conditions of example 6, but as a 4. Ufymtsev A.V. etc. Application of polyhexamethanizing agent used chlorine, which used brotylguanidine phosphate as an inhibitor to bleach water to a free chlorine content of 1 mg/l, corrosion. - Patent of Russia Me KO - 94025102, IPC? after which processing was stopped. This treatment was carried out either at night or on a day off. By 5. G.I. Baranova et al. Composition for disinfection and in the morning the chlorine level in the water was reduced to 0, 1 mg/l, storage of soft contact lenses. - Patent of Ukraine that did not cause any complaints from the user - OA - 17214 А, IPC? C1101/825; C1103/48, pub. By the end of the first day after treatment, the level of free chlorine in the water of the pool was so low that 6. Efimov, K.M., et al., Method of disinfection

KYM, which was no longer determined with the help of the usual manager of medical and swimming pools. - Analytical techniques. awning of Russia Me BO - 2145307, IPC" СО2Е1/50;

Green biofouling on the walls of Abv112/16, 218; АО1МА47/44, publication 10.02.2000 - the pool became brown, coagulated, the prototype (61.) gathered at the bottom of the pool, from where they were usually removed

Co. Computer layout 0. Gaponenko 01013131... Signatory 31313131 Print edition 111.

Ministry of Education and Science of Ukraine

State Department of Intellectual Property, str. Urytskogo, 45, Kyiv, MSP, 03680, Ukraine

SE "Ukrainian Institute of Industrial Property", str. Glazunova, 1, Kyiv - 42, 01601