Государственное Научное Учреждение "Научно-Технологический Комплекс "Институт Монокристаллов" Национальной Академии Наук Украины
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Publication of UA62958UpublicationCriticalpatent/UA62958U/en
A process for the preparation of 6-substituted 4,7-dihydro-1,2,4-triazolo[1,5-a]pyrimidines involves condensation of equimolar amounts of 3-amino-1,2,4-triazole, paraformaldehyde and methylene-active carbonyl compound in solvent at boiling. Corresponding 1,3-diketones or diacetic acid esters of formula CHCOCHX are used as methylene-active compound, water is used as solvent, and condensation is carried out for 0.25-1.0 hours up to formation of end product which is separated by filtration.
UAU201101459U2011-02-092011-02-09Process for the preparation of 6-substituted 4,7-dihydro-1,2,4-triazolo[1,5-a]pyrimidines
UA62958U
(en)
Hexahydropyrrolo[3,4-c]pyrrole derivatives and related compounds as autotaxin (atx) inhibitors and as inhibitors of the lysophosphatidic acid (lpa) production for treating e.g. renal diseases
Saturated n-heterocyclic carbene-ligand metal complex derivatives, preparing method thereof, and preparing method of silane compound by hydrosilylation reaction using the same as catalyst
PROCESS FOR THE PREPARATION OF SUBSTITUTED 7-HYDROXY-7-METHYL-2-(ALKYLTHIO)-N,5-DIARYL-4,5,6,7-TETRAHYDRO[1,2,4]TRIAZOLO[1,5-α]PYRIMIDIN-6-CARBOXAMIDES