UA135861U - METHOD OF TREATMENT AND PREVENTION OF PARASITIC DISEASES OF FISH WITH THE USE OF TOLTRAZURIL - Google Patents

Abstract

The use of a method of treating parasitic diseases of animals using toltrazuril as a method of treatment and prevention of parasitic diseases of fish.

Description

A useful model belongs to veterinary medicine, and can be used for the treatment and prevention of parasitic diseases of fish. The application of toltrazuril (Toigaigi) to fish by feeding it with feed provides 100 95-th efficiency in parasitizing protozoa (Rgoi0o270a) and monogenetic suckers (Mopodepea class). Pathogens-parasitic crustaceans and monogenetic suckers infect all types of commercial fish. They are especially dangerous for young fish, causing their death. Diseases cause a decrease in fish productivity by 20-3095. Diseases are registered in fish farms in all regions of Ukraine.

There is a method of treatment and prevention of parasitic diseases of fish with the use of organic dyes - the main bright green, violet "K" by the Department of Veterinary Medicine of the Ministry of Agriculture of the USSR on April 19, 1971 in exchange

Temporary instruction from February 8. 1968 // Veterinary legislation. - M., 1972. - T. 1. - b. 516-518.

The disadvantage is that the use of the above means directly in the aquatic environment leads to the death of not only parasitic organisms, but also useful ones - those that make up the biocenosis of the aquatic ecosystem and are a food base for fish. In addition, the amount of some preparations for use on a certain area of the reservoir is significantly reflected in the cost of processing fish and the cost price of the obtained products.

The method of treatment of parasitic diseases of warm-blooded animals using toltrazuril is closest to the claimed method. This method is used to treat diseases of the gastrointestinal tract caused by coccidia with the introduction of toltrazuril internally (Oiagtegia, M.; Megopevi, E.; Moghdapii, (5.; Mivoii, Y.; Riogeini, Y. R. (2013)). Enisasu oh

Togagitgi! 5 95 Z,izrepvsiop (VausohFb), Vaueg) apa bisiagigii (Uesohapf), dap5zep-Siiad) ip Te Sopigoi oi Eitepa 5rr. ip I atrve". Ragazyoido Rezeeagsp. 112: 163-168). Toltrazuril (SivNi«EzMzO45) belongs to the triazinon group. The mechanism of action consists in disrupting the processes of nuclear division at the cellular level. Respiratory enzymes are also blocked. As a result of such functional disturbances, death is observed parasites

The purpose of the useful model is to develop a method of treatment and prevention of fish parasitic diseases with the use of toltrazuril by feeding it to fish with food

A new functional application of a method previously used in veterinary medicine for the treatment of parasitic diseases of the gastrointestinal tract only

C5 of warm-blooded animals caused by coccidia allows us to discover new properties - prevention and treatment of parasitic diseases of fish caused by ectoparasites, which differs from warm-blooded animals and ensures the death of all forms of monogenetic suckers and protozoa parasitizing on the body and gills of fish.

The method is performed as follows.

For the anti-parasitic treatment of fish, a medicinal preparation containing the active substance - toltrazuril is used. A medical-feed mixture is prepared: the drug is mixed with compound feed, which is used for feeding fish in the amount of 0.4 g (per DR) of the drug per 1 kg of compound feed. At the same time, the combined feed is moistened, the drug is added, thoroughly mixed and fed to the fish in the form of cakes in places where it is constantly fed. The daily rate of feeding with a medicinal and fodder mixture is 595 of the total weight of fish in the reservoir. The dose of toltrazuril for such use is 20 mg per 1 kg of fish weight. The treatment-feed mixture is given to the fish at a water temperature not lower than 14 "C. During the period of anti-parasitic treatment in the ponds, the level of water exchange is increased. The next feeding of the fish with ordinary feed is carried out only under the condition that the fish completely eat the treatment-feed mixture.

Example 1. The experiment used 90 two-year-old carp spontaneously infested with pathogens of dactylohyrosis. Z groups of 30 fish each were formed. The fish of the first group were given ordinary feed without the addition of the drug. The fish of the second group were given a medicinal and feed mixture containing the drug toltrazuril at a dose of 20 mg per kg of fish weight. The organic dye purple K was added to the water with the fish of the third group at a concentration of 0.3 g/m3.

The results of Example 1 are shown in Table 1.

Example 2. The experiment used 90 two-year-old carp spontaneously infested with pathogens of ichthyophthiriasis. Z groups of 30 fish each were formed. The fish of the first group were given ordinary feed without the addition of the drug. The fish of the second group were given a medicinal and feed mixture containing the drug toltrazuril at a dose of 20 mg per kg of fish weight. The organic dye malachite green was added to the water with the fish of the third group at a concentration of 0.5 g/m. The results of Example 2 are shown in Table 2.

The analysis of the obtained results shows that the use of toltrazuril in the treatment and prevention of parasitic diseases of fish by feeding it with food provides 100 95-th efficiency in parasitizing protozoa and monogenetic suckers.

Thus, the proposed method is effective and can be used in fish farms, as well as aquariums, reservoirs, and pools.

Table 1 method of treatment and prevention of parasitic diseases of fish using toltrazuril

Dose. . . efficiency

Group Name of the drug (concentration) before processing the drug hall ГЕСзЕТи, ex/fish EE, 96, ex/fish EE, 6 PE, 95.

Toltrazuril 29.8:5D. 0 | 0 | 100 | 00 0.3 mg/dm 26,523.2 10,250.9

Control - 7777/7717 -/|700 | 271542 3245333 | - | -

EI - extensiveness of invasion; AND! - intensity of invasion;

EE - extensive efficiency; IE - intensity efficiency

Table 2

Indexes

Dose. . . efficiency

Group | Name of the drug (concentration) before processing the drug according to its LE, ex. her fish, ex. fish

Toltrazuryl 5450.5 | 0 | 0 | 00 | 100

Main Z

Cont

EI - extensiveness of invasion; AND! - intensity of invasion;

EE - extensive efficiency; IE - intensity efficiency

Claims (1)

USEFUL MODEL FORMULA Application of a method of treatment of parasitic diseases of animals using toltrazuril as a method of treatment and prevention of parasitic diseases of fish.