UA111595C2 - PYRAZIN DERIVATIVES AS ENAC BLOCKERS - Google Patents
PYRAZIN DERIVATIVES AS ENAC BLOCKERSInfo
- Publication number
- UA111595C2 UA111595C2 UAA201303053A UAA201303053A UA111595C2 UA 111595 C2 UA111595 C2 UA 111595C2 UA A201303053 A UAA201303053 A UA A201303053A UA A201303053 A UAA201303053 A UA A201303053A UA 111595 C2 UA111595 C2 UA 111595C2
- Authority
- UA
- Ukraine
- Prior art keywords
- pyrazin
- derivatives
- compounds
- enac blockers
- enac
- Prior art date
Links
Abstract
Сполуки формули (І) та їх фармацевтично прийнятні солі та сольвати, де R, R, R, R, R, R, R, R, Rта Rприймають значення, як зазначено у описі, є придатними для лікування захворювань, опосередкованих блокадою епітеліальних натрієвих каналів. Також описують фармацевтичні композиції, які містять сполуки, та способи одержання даних сполук.The compounds of formula (I) and their pharmaceutically acceptable salts and solvates, where R, R, R, R, R, R, R, R, R and R take the values as indicated in the description, are suitable for the treatment of diseases mediated by blockade of epithelial sodium channels . Also disclosed are pharmaceutical compositions containing the compounds and methods for preparing these compounds.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38398510P | 2010-09-17 | 2010-09-17 | |
PCT/EP2011/066151 WO2012035158A1 (en) | 2010-09-17 | 2011-09-16 | Pyrazine derivatives as enac blockers |
Publications (1)
Publication Number | Publication Date |
---|---|
UA111595C2 true UA111595C2 (en) | 2016-05-25 |
Family
ID=56291999
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA201303053A UA111595C2 (en) | 2010-09-17 | 2011-09-16 | PYRAZIN DERIVATIVES AS ENAC BLOCKERS |
Country Status (1)
Country | Link |
---|---|
UA (1) | UA111595C2 (en) |
-
2011
- 2011-09-16 UA UAA201303053A patent/UA111595C2/en unknown
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA201390401A1 (en) | PYRAZINE DERIVATIVES AS ENAC BLOCKERS | |
CY1124117T1 (en) | HETEROCYCLIC ALKYNYLBENZOLE COMPOUNDS AND MEDICINAL COMPOSITIONS AND USES THEREOF | |
PH12020550552A1 (en) | Inhibitors of hepatitis c virus | |
UA109010C2 (en) | Morpholino pyrividines and their use in therapy | |
EA201591195A1 (en) | NEW QUINOLON DERIVATIVES | |
PH12014501542A1 (en) | Substituted pyrrolidine -2- carboxamides | |
EA201491672A1 (en) | HETEROCYCLINE COMPOUNDS AS MEK INHIBITORS | |
UA109868C2 (en) | N -alkyltriazole compounds asr | |
PH12014501514A1 (en) | New azetidine derivatives, pharmaceutical compositions and uses thereof | |
EA201490471A1 (en) | PYRIDAZINOUS COMPOUNDS AND THEIR APPLICATION AS DAAO INHIBITORS | |
IN2015DN01119A (en) | ||
EA201500298A1 (en) | ALCOXYPHAZOLES AS ACTIVATORS OF SOLUBLE GUANYLATZYCLASES | |
IN2012DN03182A (en) | ||
EA201600434A1 (en) | APPLICATION OF DERIVATIVES OF BENZIMIDAZOLPROLINE | |
IN2014DN09347A (en) | ||
WO2012135615A3 (en) | Enopeptins, uses thereof, and methods of synthesis thereto | |
PH12015500111A1 (en) | Difluorolactam compositions for ep4-mediated osteo related diseases and conditions | |
MX2015001657A (en) | Lpar - substituted cyanopyrazole compounds. | |
GEP20156269B (en) | New secondary 8-hydroxyquinoline-7- carboxamide derivatives | |
UA111595C2 (en) | PYRAZIN DERIVATIVES AS ENAC BLOCKERS | |
MX2013014950A (en) | Compounds for the treatment of cancers associated with human papillomavirus. | |
TN2013000102A1 (en) | Pyrazine derivatives as enac blockers | |
CA2905957C (en) | Pyrazole compounds, compositions and methods for treatment of degenerative diseases and disorders | |
UA111851C2 (en) | PIRIDASINONE COMPOUNDS AND THEIR USE AS DAAO INHIBITORS |