UA111595C2 - PYRAZIN DERIVATIVES AS ENAC BLOCKERS - Google Patents

PYRAZIN DERIVATIVES AS ENAC BLOCKERS

Info

Publication number
UA111595C2
UA111595C2 UAA201303053A UAA201303053A UA111595C2 UA 111595 C2 UA111595 C2 UA 111595C2 UA A201303053 A UAA201303053 A UA A201303053A UA A201303053 A UAA201303053 A UA A201303053A UA 111595 C2 UA111595 C2 UA 111595C2
Authority
UA
Ukraine
Prior art keywords
pyrazin
derivatives
compounds
enac blockers
enac
Prior art date
Application number
UAA201303053A
Other languages
Ukrainian (uk)
Inventor
Гурдіп Бхелей
Лі Едвардс
Кетрін Хоушем
Пітер Хант
Нікола Сміт
Original Assignee
Новартіс Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Новартіс Аг filed Critical Новартіс Аг
Priority claimed from PCT/EP2011/066151 external-priority patent/WO2012035158A1/en
Publication of UA111595C2 publication Critical patent/UA111595C2/en

Links

Abstract

Сполуки формули (І) та їх фармацевтично прийнятні солі та сольвати, де R, R, R, R, R, R, R, R, Rта Rприймають значення, як зазначено у описі, є придатними для лікування захворювань, опосередкованих блокадою епітеліальних натрієвих каналів. Також описують фармацевтичні композиції, які містять сполуки, та способи одержання даних сполук.The compounds of formula (I) and their pharmaceutically acceptable salts and solvates, where R, R, R, R, R, R, R, R, R and R take the values as indicated in the description, are suitable for the treatment of diseases mediated by blockade of epithelial sodium channels . Also disclosed are pharmaceutical compositions containing the compounds and methods for preparing these compounds.

UAA201303053A 2010-09-17 2011-09-16 PYRAZIN DERIVATIVES AS ENAC BLOCKERS UA111595C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38398510P 2010-09-17 2010-09-17
PCT/EP2011/066151 WO2012035158A1 (en) 2010-09-17 2011-09-16 Pyrazine derivatives as enac blockers

Publications (1)

Publication Number Publication Date
UA111595C2 true UA111595C2 (en) 2016-05-25

Family

ID=56291999

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201303053A UA111595C2 (en) 2010-09-17 2011-09-16 PYRAZIN DERIVATIVES AS ENAC BLOCKERS

Country Status (1)

Country Link
UA (1) UA111595C2 (en)

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