Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2011/066151external-prioritypatent/WO2012035158A1/en
Application filed by Novartis AgfiledCriticalNovartis Ag
Publication of TN2013000102A1publicationCriticalpatent/TN2013000102A1/en
Compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 have the meanings as indicated in the specification, are useful for treating diseases mediated by blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
TNP2013000102A2011-09-162013-03-12Pyrazine derivatives as enac blockers
TN2013000102A1
(en)