TN2013000102A1 - Pyrazine derivatives as enac blockers - Google Patents

Pyrazine derivatives as enac blockers

Info

Publication number
TN2013000102A1
TN2013000102A1 TNP2013000102A TN2013000102A TN2013000102A1 TN 2013000102 A1 TN2013000102 A1 TN 2013000102A1 TN P2013000102 A TNP2013000102 A TN P2013000102A TN 2013000102 A TN2013000102 A TN 2013000102A TN 2013000102 A1 TN2013000102 A1 TN 2013000102A1
Authority
TN
Tunisia
Prior art keywords
compounds
pyrazine derivatives
enac blockers
enac
blockers
Prior art date
Application number
TNP2013000102A
Other languages
French (fr)
Inventor
Gurdip Bhalay
Lee Edwards
Catherine Howsham
Peter Hunt
Nichola Smith
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2011/066151 external-priority patent/WO2012035158A1/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of TN2013000102A1 publication Critical patent/TN2013000102A1/en

Links

Abstract

Compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 have the meanings as indicated in the specification, are useful for treating diseases mediated by blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
TNP2013000102A 2011-09-16 2013-03-12 Pyrazine derivatives as enac blockers TN2013000102A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2011/066151 WO2012035158A1 (en) 2010-09-17 2011-09-16 Pyrazine derivatives as enac blockers

Publications (1)

Publication Number Publication Date
TN2013000102A1 true TN2013000102A1 (en) 2014-06-25

Family

ID=54360789

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2013000102A TN2013000102A1 (en) 2011-09-16 2013-03-12 Pyrazine derivatives as enac blockers

Country Status (1)

Country Link
TN (1) TN2013000102A1 (en)

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