UA106050C2 - Normal;heading 1;heading 2;heading 3;COMPOSITION OF PD-1 ANTAGONIST AND A POTENTIATING AGENT FOR SIMULATING A T CELL RESPONSE - Google Patents

Normal;heading 1;heading 2;heading 3;COMPOSITION OF PD-1 ANTAGONIST AND A POTENTIATING AGENT FOR SIMULATING A T CELL RESPONSE

Info

Publication number
UA106050C2
UA106050C2 UAA201103619A UAA201103619A UA106050C2 UA 106050 C2 UA106050 C2 UA 106050C2 UA A201103619 A UAA201103619 A UA A201103619A UA A201103619 A UAA201103619 A UA A201103619A UA 106050 C2 UA106050 C2 UA 106050C2
Authority
UA
Ukraine
Prior art keywords
heading
antagonist
simulating
normal
composition
Prior art date
Application number
UAA201103619A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Соломон Лангерман
Лінда Лю
Original Assignee
Ампліммун, Інк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ампліммун, Інк. filed Critical Ампліммун, Інк.
Priority claimed from PCT/US2009/004825 external-priority patent/WO2010027423A2/en
Publication of UA106050C2 publication Critical patent/UA106050C2/en

Links

Abstract

Methods of treating cancer and infectious diseases utilizing a treatment regimen comprising administering a compound that reduces inhibitory signal transduction in T cells, in combination with a potentiating agent, such as cyclophosphamide, to produce potent T cell mediated responses, are described. Compositions comprising the PD-1 antagonists and potentiating agents useful in the methods of the invention are also disclosed.
UAA201103619A 2008-08-25 2009-08-25 Normal;heading 1;heading 2;heading 3;COMPOSITION OF PD-1 ANTAGONIST AND A POTENTIATING AGENT FOR SIMULATING A T CELL RESPONSE UA106050C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9170908P 2008-08-25 2008-08-25
PCT/US2009/004825 WO2010027423A2 (en) 2008-08-25 2009-08-25 Compositions of pd-1 antagonists and methods of use

Publications (1)

Publication Number Publication Date
UA106050C2 true UA106050C2 (en) 2014-07-25

Family

ID=56281780

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201103619A UA106050C2 (en) 2008-08-25 2009-08-25 Normal;heading 1;heading 2;heading 3;COMPOSITION OF PD-1 ANTAGONIST AND A POTENTIATING AGENT FOR SIMULATING A T CELL RESPONSE

Country Status (1)

Country Link
UA (1) UA106050C2 (en)

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