UA106050C2 - Normal;heading 1;heading 2;heading 3;COMPOSITION OF PD-1 ANTAGONIST AND A POTENTIATING AGENT FOR SIMULATING A T CELL RESPONSE
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Normal;heading 1;heading 2;heading 3;COMPOSITION OF PD-1 ANTAGONIST AND A POTENTIATING AGENT FOR SIMULATING A T CELL RESPONSE
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Application filed by Ампліммун, Інк.filedCriticalАмпліммун, Інк.
Priority claimed from PCT/US2009/004825external-prioritypatent/WO2010027423A2/en
Publication of UA106050C2publicationCriticalpatent/UA106050C2/en
Methods of treating cancer and infectious diseases utilizing a treatment regimen comprising administering a compound that reduces inhibitory signal transduction in T cells, in combination with a potentiating agent, such as cyclophosphamide, to produce potent T cell mediated responses, are described. Compositions comprising the PD-1 antagonists and potentiating agents useful in the methods of the invention are also disclosed.
UAA201103619A2008-08-252009-08-25Normal;heading 1;heading 2;heading 3;COMPOSITION OF PD-1 ANTAGONIST AND A POTENTIATING AGENT FOR SIMULATING A T CELL RESPONSE
UA106050C2
(en)