TWM659270U - Soft capsule structure containing fish oil - Google Patents

Soft capsule structure containing fish oil Download PDF

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TWM659270U
TWM659270U TW113204200U TW113204200U TWM659270U TW M659270 U TWM659270 U TW M659270U TW 113204200 U TW113204200 U TW 113204200U TW 113204200 U TW113204200 U TW 113204200U TW M659270 U TWM659270 U TW M659270U
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fish oil
soft capsule
capsule structure
fatty acids
core body
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TW113204200U
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林東慶
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大研生醫國際股份有限公司
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Abstract

本創作公開一種含有魚油的軟膠囊結構。所述含有魚油的軟膠囊結構包括一核心體以及包覆所述核心體的一外覆層。所述核心體包含多個有效活性成分單元,其中,所述有效活性成分單元包含魚油萃取物。The invention discloses a soft capsule structure containing fish oil. The soft capsule structure containing fish oil comprises a core body and an outer coating layer covering the core body. The core body comprises a plurality of effective active ingredient units, wherein the effective active ingredient units comprise fish oil extract.

Description

含有魚油的軟膠囊結構Fish oil softgel structure

本創作涉及一種膠囊結構,特別是涉及一種含有魚油的軟膠囊結構。The invention relates to a capsule structure, in particular to a soft capsule structure containing fish oil.

ω-3脂肪酸(Omega-3 fatty acids)是一種多元不飽和脂肪酸,人體並無法自行直接合成ω-3脂肪酸,必須通過飲食攝取來獲得。ω-3脂肪酸最主要的脂肪酸有3種:二十碳五烯酸(Eicosapentaenoic acid, EPA)、二十二碳六烯酸(Docosahexaenoic Acid, DHA)以及α-亞麻酸(alpha-linolenic acid, ALA)。其中,EPA和DHA被發現主要存在於海洋動植物油中,而ALA則是主要存在於植物油中。一般而言,人們主要是通過攝取魚類中的魚油來獲得ω-3脂肪酸。Omega-3 fatty acids are a type of polyunsaturated fatty acid. The human body cannot synthesize omega-3 fatty acids directly and must be obtained through diet. There are three main types of omega-3 fatty acids: eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and alpha-linolenic acid (ALA). Among them, EPA and DHA are found mainly in marine animal and plant oils, while ALA is mainly found in vegetable oils. Generally speaking, people mainly obtain omega-3 fatty acids by consuming fish oil from fish.

現有研究發現ω-3脂肪酸具有多種有益人體的功能,包含:有助於降低血壓、提高新陳代謝、降低發炎反應、有助於心理健康、減少三酸甘油酯(Triglycerides)合成和血管脂肪斑塊的生成等。因此,WHO建議每日攝取300毫克至500毫克的ω-3脂肪酸,美國心臟協會則是建議每日攝取650毫克至1000毫克的ω-3脂肪酸。然而,現代人的飲食不均衡,且魚類攝取量並不高,因此,魚油類保健食品成為補充ω-3脂肪酸的替代方案。Existing studies have found that omega-3 fatty acids have many beneficial functions for the human body, including: helping to lower blood pressure, improving metabolism, reducing inflammation, helping mental health, reducing triglyceride synthesis and the formation of vascular fatty plaques, etc. Therefore, WHO recommends daily intake of 300 mg to 500 mg of omega-3 fatty acids, and the American Heart Association recommends daily intake of 650 mg to 1000 mg of omega-3 fatty acids. However, modern people's diet is unbalanced, and the intake of fish is not high. Therefore, fish oil health foods have become an alternative to supplement omega-3 fatty acids.

然而,市面上的魚油保健食品中的ω-3脂肪酸濃度參差不齊,且不同型態的魚油會影響吸收率。故,如何通過結構設計的改良,來提升魚油的吸收率以達到保健效果,已成為該項事業所欲解決的重要課題之一。However, the concentration of ω-3 fatty acids in fish oil health foods on the market varies, and different types of fish oil will affect the absorption rate. Therefore, how to improve the absorption rate of fish oil to achieve health effects through structural design improvements has become one of the important issues that this industry wants to solve.

本創作所要解決的技術問題在於,針對現有技術的不足提供一種含有魚油的軟膠囊結構,其可以有助於促進新陳代謝、提升免疫力、降低三酸甘油酯以及降低發炎反應等效果。所述含有魚油的軟膠囊結構其包括一核心體以及一外覆層。所述核心體包括多個有效活性成分單元,其中多個所述有效活性成分單元包含魚油萃取物。所述外覆層包覆所述核心體。The technical problem to be solved by this invention is to provide a soft capsule structure containing fish oil to address the deficiencies of the prior art, which can help promote metabolism, enhance immunity, reduce triglycerides, and reduce inflammatory reactions. The soft capsule structure containing fish oil includes a core body and an outer coating. The core body includes a plurality of effective active ingredient units, wherein a plurality of the effective active ingredient units include fish oil extracts. The outer coating covers the core body.

在本創作其中一實施例中,所述含有魚油的軟膠囊結構的粒徑大小為1公分至2公分。In one embodiment of the present invention, the particle size of the soft capsule structure containing fish oil is 1 cm to 2 cm.

在本創作其中一實施例中,所述外覆層的厚度為0.5公釐至3公釐之間,且所述外覆層具有平滑表面。In one embodiment of the present invention, the thickness of the outer covering layer is between 0.5 mm and 3 mm, and the outer covering layer has a smooth surface.

在本創作其中一實施例中,所述外覆層的材料包含明膠。In one embodiment of the present invention, the material of the outer covering layer includes gelatin.

在本創作其中一實施例中,所述魚油萃取物包含ω-3脂肪酸(Omega-3 polyunsaturated fatty acids, PUFAs),以及所述ω-3脂肪酸包含二十碳五烯酸(Eicosapentaenoic acid, EPA)以及二十二碳六烯酸(Docosahexaenoic Acid, DHA)。In one embodiment of the present invention, the fish oil extract contains omega-3 polyunsaturated fatty acids (PUFAs), and the omega-3 fatty acids contain eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

在本創作其中一實施例中,基於所述核心體的重量,所述ω-3脂肪酸占80%重量百分比至90%重量百分比。In one embodiment of the present invention, based on the weight of the core body, the ω-3 fatty acids account for 80% to 90% by weight.

本創作的其中一有益效果在於,本創作所提供的含有魚油的軟膠囊結構,其能通過“核心體包括多個有效活性成分單元,其中多個所述有效活性成分單元包含魚油萃取物”以及“所述外覆層包覆所述核心體”的技術方案,以促進新陳代謝、提升免疫力、降低三酸甘油酯以及降低發炎反應。One of the beneficial effects of the present invention is that the fish oil-containing soft capsule structure provided by the present invention can promote metabolism, enhance immunity, reduce triglycerides and reduce inflammatory response through the technical solutions of "the core body includes multiple effective active ingredient units, wherein multiple effective active ingredient units contain fish oil extracts" and "the outer layer covers the core body".

為使能更進一步瞭解本創作的特徵及技術內容,請參閱以下有關本創作的詳細說明與圖式,然而所提供的圖式僅用於提供參考與說明,並非用來對本創作加以限制。In order to further understand the features and technical content of this work, please refer to the following detailed description and diagrams of this work. However, the diagrams provided are only used for reference and explanation and are not used to limit this work.

以下是通過特定的具體實施例來說明本創作所公開有關“含有魚油的軟膠囊結構”的實施方式,本領域技術人員可由本說明書所公開的內容瞭解本創作的優點與效果。本創作可通過其他不同的具體實施例加以施行或應用,本說明書中的各項細節也可基於不同觀點與應用,在不背離本創作的構思下進行各種修改與變更。另外,本創作的附圖僅為簡單示意說明,並非依實際尺寸的描繪,事先聲明。以下的實施方式將進一步詳細說明本創作的相關技術內容,但所公開的內容並非用以限制本創作的保護範圍。另外,本文中所使用的術語“或”,應視實際情況可能包括相關聯的列出項目中的任一個或者多個的組合。The following is an explanation of the implementation of the "soft capsule structure containing fish oil" disclosed in this creation through specific concrete embodiments. Technical personnel in this field can understand the advantages and effects of this creation from the content disclosed in this manual. This creation can be implemented or applied through other different specific embodiments, and the details in this manual can also be modified and changed in various ways based on different viewpoints and applications without departing from the concept of this creation. In addition, the drawings of this creation are only for simple schematic illustrations and are not depicted according to actual size. Please note in advance. The following implementation will further explain the relevant technical content of this creation in detail, but the disclosed content is not used to limit the scope of protection of this creation. In addition, the term "or" used herein may include any one or more combinations of the associated listed items as appropriate.

[第一實施例][First embodiment]

參閱圖1至圖2所示,本創作第一實施例提供一種含有魚油的軟膠囊結構S,其包括:一核心體10以及包覆所述核心體10的一外覆層20。所述核心體10包含多個有效活性成分單元11,其中,所述有效活性成分單元11包含魚油萃取物。所述魚油萃取物可以包含ω-3脂肪酸(Omega-3 fatty acids)。Referring to FIG. 1 and FIG. 2 , the first embodiment of the invention provides a soft capsule structure S containing fish oil, which includes: a core body 10 and an outer coating 20 covering the core body 10. The core body 10 contains a plurality of effective active ingredient units 11, wherein the effective active ingredient units 11 contain fish oil extract. The fish oil extract may contain omega-3 fatty acids.

ω-3脂肪酸屬於人體無法自行合成的必需脂肪酸,需要通過飲食攝取來獲得,ω-3脂肪酸主要包含二十碳五烯酸(Eicosapentaenoic acid, EPA)以及二十二碳六烯酸(Docosahexaenoic Acid, DHA)。Omega-3 fatty acids are essential fatty acids that cannot be synthesized by the human body and must be obtained through diet. Omega-3 fatty acids mainly include eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

一般魚油中的ω-3脂肪酸濃度平均為20%至60%之間,並無法確保品質。且相較於高濃度ω-3脂肪酸的魚油,低濃度的魚油中含有較多膽固醇以及其他成分,因此,在實際施用時,服用較多低濃度ω-3脂肪酸的魚油反而有可能會導致膽固醇過高。因此,魚油中的ω-3脂肪酸濃度相當重要,應挑選ω-3脂肪酸濃度較高的魚油攝取,才有益健康。The average concentration of omega-3 fatty acids in general fish oil is between 20% and 60%, and the quality cannot be guaranteed. Compared with fish oil with high concentration of omega-3 fatty acids, fish oil with low concentration contains more cholesterol and other ingredients. Therefore, in actual use, taking more fish oil with low concentration of omega-3 fatty acids may lead to excessive cholesterol. Therefore, the concentration of omega-3 fatty acids in fish oil is very important, and fish oil with higher concentration of omega-3 fatty acids should be selected for intake, which is beneficial to health.

需要注意的是,魚油萃取物會依據萃取方式的不同,而產生不同的吸收效果,通常分為以下3種類別:TG(Triglyceride)型、EE(Ethyl Ester)型以及rTG型(Re-Esterified Triglyceride)。TG型為天然型態,屬於最傳統的魚油萃取,將魚的皮下脂肪通過基本精煉過程除去雜質,將魚油維持在三酸甘油酯型態,雖然易被吸收且價格低,然而ω-3脂肪酸濃度偏低(約為30%至50%),即EPA與DHA濃度偏低。為了提高ω-3脂肪酸濃度,則衍生出EE型魚油,其是進一步利用酯化處理,將魚油中的不飽和脂肪酸分離,成為乙酯型態,以提高ω-3脂肪酸濃度,但其吸收率反而因此而降低。最後,有別於以往的有機溶劑萃取,rTG型魚油採用超臨界萃取法,並將通過酯化處理後再還原為三酸甘油酯型,因此ω-3脂肪酸濃度可以達80%至99%,且吸收率最高,而成本較TG型及EE型高。It should be noted that fish oil extracts will produce different absorption effects depending on the extraction method. They are usually divided into the following three categories: TG (Triglyceride) type, EE (Ethyl Ester) type and rTG type (Re-Esterified Triglyceride). TG type is a natural type and the most traditional fish oil extraction. The fish's subcutaneous fat is subjected to a basic refining process to remove impurities and maintain the fish oil in a triglyceride form. Although it is easily absorbed and inexpensive, the concentration of ω-3 fatty acids is low (about 30% to 50%), that is, the concentration of EPA and DHA is low. In order to increase the concentration of ω-3 fatty acids, EE type fish oil is derived. It further uses esterification to separate the unsaturated fatty acids in the fish oil into an ethyl ester form to increase the concentration of ω-3 fatty acids, but its absorption rate is reduced as a result. Finally, unlike previous organic solvent extraction, rTG fish oil uses supercritical extraction and is esterified before being reduced to triglyceride. Therefore, the concentration of ω-3 fatty acids can reach 80% to 99%, and the absorption rate is the highest, but the cost is higher than TG and EE types.

本實施例中,所述魚油萃取物是使用遠洋小型魚為原料,並通過超臨界流體萃取技術以及超臨界流體層析法所獲得的rTG型魚油萃取物,因此,本創作的所述魚油萃取物的ω-3脂肪酸可以達80%至90%(較佳為84%以上),且其中二十碳五烯酸與二十二碳六烯酸的濃度可以達到80%至90%(較佳為80%以上),可以有效吸收,提升新陳代謝。此外,本創作的魚油萃取物中並不含有化學溶劑、水、糖、膽固醇或飽和脂肪酸。舉例來說,在每一個軟膠囊結構S的核心體10中可以包含500毫克至700毫克的ω-3脂肪酸,且其中可包含240毫克至336毫克的二十碳五烯酸以及160毫克至224毫克的二十二碳六烯酸。另外,於實際施用時,有效活性成分單元11還可以進一步包含抗氧化劑(例如:混合濃縮生育醇)、維生素E或其組合。然而,本創作不以上述所舉的例子為限。In this embodiment, the fish oil extract is a rTG fish oil extract obtained by using small ocean fish as raw materials and supercritical fluid extraction technology and supercritical fluid chromatography. Therefore, the ω-3 fatty acids in the fish oil extract of this invention can reach 80% to 90% (preferably 84% or more), and the concentration of eicosapentaenoic acid and docosahexaenoic acid can reach 80% to 90% (preferably 80% or more), which can be effectively absorbed and enhance metabolism. In addition, the fish oil extract of this invention does not contain chemical solvents, water, sugar, cholesterol or saturated fatty acids. For example, the core body 10 of each soft capsule structure S may contain 500 mg to 700 mg of ω-3 fatty acids, and may contain 240 mg to 336 mg of eicosapentaenoic acid and 160 mg to 224 mg of docosahexaenoic acid. In addition, during actual administration, the effective active ingredient unit 11 may further contain an antioxidant (e.g., mixed tocopherol concentrate), vitamin E, or a combination thereof. However, the invention is not limited to the above examples.

舉例而言,外覆層20的材料可以包含明膠(Gelatin)、甘油以及純水,但並不以此為限。更進一步而言,外覆層20的材料可進一步包含但不限於色素、抗氧化劑、殺菌劑、賦形劑、成膜劑、甜味劑、酸味劑、清涼劑等成分。此外,外覆層20的厚度大約介於0.5公釐至3公釐之間,且可以具有平滑外表面或粗糙外表面。在其中一具體實施例中,每一粒的軟膠囊結構S的總重為820毫克,其中,外覆層20的重量占220毫克,核心體的重量占600毫克。然而,上述所舉的例子只是其中一可行的實施例而並非用以限定本創作。For example, the material of the outer coating 20 may include gelatin, glycerin and pure water, but is not limited thereto. Further, the material of the outer coating 20 may further include but is not limited to components such as pigments, antioxidants, bactericides, shaping agents, film-forming agents, sweeteners, acidulants, and cooling agents. In addition, the thickness of the outer coating 20 is approximately between 0.5 mm and 3 mm, and may have a smooth outer surface or a rough outer surface. In one specific embodiment, the total weight of each soft capsule structure S is 820 mg, wherein the weight of the outer coating 20 accounts for 220 mg, and the weight of the core body accounts for 600 mg. However, the above-mentioned example is only one of the feasible embodiments and is not used to limit this creation.

在舉例來說,在其中一具體實施例中,每一粒的軟膠囊結構S中可以包含504毫克的ω-3脂肪酸,且其中含有288毫克的二十碳五烯酸以及192毫克的二十二碳六烯酸,使用者可以於每日服用2顆。然而,上述所舉的例子只是其中一可行的實施例而並非用以限定本創作。For example, in one specific embodiment, each soft capsule structure S may contain 504 mg of ω-3 fatty acids, including 288 mg of eicosapentaenoic acid and 192 mg of docosahexaenoic acid, and the user may take 2 capsules per day. However, the above example is only a feasible embodiment and is not intended to limit the present invention.

具體而言,軟膠囊結構S的粒徑大小可以介於1公分至2公分,且軟膠囊結構S可以為球體、橢圓體或立方體的形狀,但不以此為限。Specifically, the particle size of the soft capsule structure S may be between 1 cm and 2 cm, and the soft capsule structure S may be in the shape of a sphere, an ellipse, or a cube, but is not limited thereto.

軟膠囊的遮光性好,可以避免光敏感原料被光線照射,也較容易遞送脂溶性營養素。一般而言,軟膠囊是將液態或糊狀的內容物以薄膜包覆成型;在本實施例中,含有魚油的軟膠囊結構S的製造方法可以為輪轉式製造方法或是無縫式製造方法,但不以此為限。輪轉式製造方法是使用在兩側設置帶狀的包覆膜連動至兩圓筒模具之間,兩帶狀包覆膜之間設有盛裝有內容液(有效活性成分單元)的一活塞噴頭以將內容物注入於兩包覆膜之間,接著由兩圓筒模具切出,形成膠囊。無縫式製造方法則是使用雙層流液的注流管柱,外層流液為包覆材料液,內側為內容液(有效活性成分單元),以一定間隔切斷,使包覆材料液包覆內容液,並定型為膠囊。然而,上述所舉的例子只是其中一可行的實施例而並非用以限定本創作。Soft capsules have good light-shielding properties, which can prevent light-sensitive raw materials from being exposed to light, and are also easier to deliver fat-soluble nutrients. Generally speaking, soft capsules are formed by coating liquid or paste contents with a film; in this embodiment, the manufacturing method of the soft capsule structure S containing fish oil can be a rotary manufacturing method or a seamless manufacturing method, but is not limited to this. The rotary manufacturing method uses a strip-shaped coating film arranged on both sides to be linked to the space between two cylindrical molds, and a piston nozzle containing a content liquid (effective active ingredient unit) is arranged between the two strip-shaped coating films to inject the content between the two coating films, and then cut out by the two cylindrical molds to form a capsule. The seamless manufacturing method is to use a double-layer fluid injection column, the outer layer of the fluid is the coating material fluid, and the inner layer is the content fluid (effective active ingredient unit), which is cut at a certain interval so that the coating material fluid covers the content fluid and is formed into a capsule. However, the above example is only one of the feasible embodiments and is not intended to limit the present invention.

[實施例的有益效果][Beneficial Effects of Embodiments]

本創作的其中一有益效果在於,本創作所提供的含有魚油的軟膠囊結構,其能通過“核心體包括多個有效活性成分單元,其中多個所述有效活性成分單元包含魚油萃取物”以及“所述外覆層包覆所述核心體”的技術方案,以促進新陳代謝、提升免疫力、降低三酸甘油酯以及降低發炎反應。One of the beneficial effects of the present invention is that the fish oil-containing soft capsule structure provided by the present invention can promote metabolism, enhance immunity, reduce triglycerides and reduce inflammatory response through the technical solutions of "the core body includes multiple effective active ingredient units, wherein multiple effective active ingredient units contain fish oil extracts" and "the outer layer covers the core body".

以上所公開的內容僅為本創作的優選可行實施例,並非因此侷限本創作的申請專利範圍,所以凡是運用本創作說明書及圖式內容所做的等效技術變化,均包含於本創作的申請專利範圍內。The above disclosed contents are only the preferred feasible embodiments of the present invention and do not limit the scope of the patent application of the present invention. Therefore, all equivalent technical changes made by using the instructions and diagrams of the present invention are included in the scope of the patent application of the present invention.

S:軟膠囊結構 10:核心體 11:有效活性成分單元 20:外覆層S: Soft capsule structure 10: Core body 11: Active ingredient unit 20: Outer layer

圖1為本創作第一實施例的含有魚油的軟膠囊結構的立體透視示意圖。FIG1 is a three-dimensional perspective schematic diagram of the structure of a soft capsule containing fish oil according to the first embodiment of the present invention.

圖2為本創作第一實施例的含有魚油的軟膠囊結構的剖面示意圖。FIG2 is a schematic cross-sectional view of the structure of a soft capsule containing fish oil according to the first embodiment of the present invention.

S:軟膠囊結構 S: Soft capsule structure

10:核心體 10: Core body

11:有效活性成分單元 11: Effective active ingredient unit

20:外覆層 20: Outer covering

Claims (6)

一種含有魚油的軟膠囊結構,其包括: 一核心體,其包含多個有效活性成分單元,其中,所述有效活性成分單元包含魚油萃取物;以及 一外覆層,其包覆所述核心體。 A soft capsule structure containing fish oil, comprising: a core body, which contains a plurality of effective active ingredient units, wherein the effective active ingredient units contain fish oil extract; and an outer coating layer, which covers the core body. 如請求項1所述的含有魚油的軟膠囊結構,其粒徑大小為1公分至2公分。The fish oil-containing soft capsule structure as described in claim 1 has a particle size of 1 cm to 2 cm. 如請求項1所述的含有魚油的軟膠囊結構,其中,所述外覆層的厚度為0.5公釐至3公釐之間,且所述外覆層具有平滑表面。The fish oil-containing soft capsule structure as described in claim 1, wherein the thickness of the outer coating layer is between 0.5 mm and 3 mm, and the outer coating layer has a smooth surface. 如請求項1所述的含有魚油的軟膠囊結構,其中,所述外覆層的材料包含明膠。The fish oil-containing soft capsule structure as described in claim 1, wherein the material of the outer coating layer comprises gelatin. 如請求項1所述的含有魚油的軟膠囊結構,其中,魚油萃取物包含ω-3脂肪酸,以及所述ω-3脂肪酸包含二十碳五烯酸以及二十二碳六烯酸。The fish oil-containing soft capsule structure as described in claim 1, wherein the fish oil extract contains ω-3 fatty acids, and the ω-3 fatty acids contain eicosapentaenoic acid and docosahexaenoic acid. 如請求項5所述的含有魚油的軟膠囊結構,其中,基於所述核心體的重量,所述ω-3脂肪酸占80%重量百分比至90%重量百分比。The fish oil-containing soft capsule structure as described in claim 5, wherein the ω-3 fatty acid accounts for 80% to 90% by weight based on the weight of the core.
TW113204200U 2024-04-26 2024-04-26 Soft capsule structure containing fish oil TWM659270U (en)

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