TWM624636U - Structure of micro-complex with ingredients and yeast - Google Patents

Abstract

A micro-complex contained ingredients and yeast. There are two layers of micro-complex, the core in the middle and the clad coating on it. The core is contained yeast, prebiotics, natural ingredients, and the mix. The clad is coated on the core to avoid the ingredients being decomposed during swallowing and promote the stability and absorption of the core.

Description

Particulate structure with active ingredient yeast

This creation is about a particle structure containing active ingredient yeast, especially a double-layer composite particle structure including at least a core body and a covering body, which is used to protect the active ingredient from being damaged by gastric acid and adjust the pet's auto-inflammation.

Traditionally, pet nutrition products are mainly in the form of lozenges or powders, which are susceptible to temperature, humidity, and even bacterial contamination without special treatment; and after consumption, untreated nutrition products Easily broken down by stomach acid and enzymes. Therefore, it is one of the most important issues to improve the coating of active ingredients and improve storage stability and effectiveness.

At present, pet atopic dermatitis and auto-inflammatory diseases are mostly controlled by antihistamines and steroids. After clinical statistics, antihistamines are only effective for about 30% of animals; steroids are the most commonly used coping methods, but long-term use Steroids can cause permanent and serious sequelae. Therefore, more and more people use enzymes and probiotics to replace the heavy drug control, but both probiotics and enzymes are easily destroyed by gastric acid, and preservation is also another major problem. big hazard.

In view of this, the purpose of this novel creation is to provide a particle structure that protects yeast and active ingredients from gastric acid damage and can improve storage stability, comprising a core body and a coating body, and the core body is the space in the center of the particle. , is the most important part of the particles carried by the particles, It should contain active ingredients and yeast, which can adjust the constitution, protect intestinal health, and adjust the inflammatory response in the body. The core body should be completely wrapped in the coating body to prevent leakage. The covering body should cover the periphery of the core body, and has the effect of isolating the core body and the surrounding environment. The covering body can protect the active ingredient during in vivo delivery and improve the storage stability.

According to the above-mentioned active ingredient-containing yeast particle structure, the source of the active ingredient includes animals, plants, microorganisms and the like.

According to the aforementioned microparticle structure containing yeast as an active ingredient, the yeast is Saccharomyces cerevisiae or a derivative thereof.

According to the aforementioned microparticle structure of yeast containing active ingredient, the coating includes polysaccharide derivatives such as dextran, starch, cellulose, cyclodextrin, etc.

According to the aforementioned particulate structure of yeast containing active ingredient, wherein the particulate structure comprises moisture-proofing agent, antioxidant, hygroscopic agent, chelating agent, swelling agent, adhesive, etc.

According to the aforementioned microparticle structure of the yeast containing the active ingredient, it can be used as powder, capsule, powder packet or lozenge.

11: Covering body

12: Core Body

21: Active Ingredients

22: Yeast

23: Prebiotics

[Fig. 1] A cross-sectional view of the microparticle structure containing the active ingredient yeast

The following provides an illustrative description for the implementation of this creation, but this is not the only form of implementation of this creation. The method steps and synthesis sequence of the embodiments in the creation can still be based on Different requirements to achieve equal effect of implementation.

Referring to the description of FIG. 1 , the following detailed description supplements and specific embodiments will be described. The microparticle structure containing the active ingredient yeast disclosed in the present invention includes two parts, a core body 12 and a coating body 11 , and the coating body 11 coats the outer layer of the core body 12 for protecting the components of the core body. For weight distribution, the core 12 is about 60-90%, preferably 70-80%. The covering body 11 accounts for about 10-40%, and the best is 20-30%.

In the preferred embodiment of this creation, the core body 12 should include prebiotics 23 to provide a stable environment for the yeast 22 in the microparticles, build the basic structure of the core body, and release it into the body to provide intestinal probiotics to stabilize the positive bacteria. The prebiotics 23 include but are not limited to xylo-oligosaccharides, inulin, lactose, galactose, oligosaccharides, fructooligosaccharides and the like. The prebiotics 23 contained in the core body 12 should account for 20-40% of the total weight.

In the preferred embodiment of this creation, the yeast 22 and the active ingredients 21 should be fully mixed with the prebiotics 23 to form the core body 12, and the yeast 22 is most preferably S. cerevisiae; the active ingredients 21 include but are not limited to theanine, Q10, Tea, resveratrol, vitamin B group, vitamin C, herbal extracts, ceramide, sphingosine, etc. Yeast 22 and active ingredient 21 should account for 20-50% of the total weight.

In the preferred embodiment of this creation, the core body 12 should be mixed with moisture-proofing agent, antioxidant, moisture absorbing agent, chelating agent, swelling agent, and adhesive according to the situation, and the final core body 12 should be spherical after spraying, granulating and drying. for subsequent wrapping.

In a preferred embodiment of the present invention, the cladding body 11 should be wrapped around the outside of the core body to isolate the core body 12 from the external environment and protect the components of the core body 12 from external factors. The coating body 11 can form a stable granular structure, which can keep the granularity during granulation and protect the components of the core body 12 in the stomach. Coating ingredients used include but are not limited to dextran, starch, cellulose, Dextrin, etc.

The coating body 11 is added to the granular core body 12 and mixed, and the two sides should be mixed for more than 30 minutes to ensure complete coating and uniformity. Dry granulation should be performed after 30 minutes, and the binders and lubricants should be adjusted appropriately to prevent sticking or disintegration.

According to the embodiments of the above disclosure, the microparticle structure of yeast containing the active ingredient of the present creation is disclosed, and the components of the core body 12 are protected by the outer coating body 11 in the structure, which can not only be used as a long-term preservation dosage form, but also can be free from the core body. The active ingredients of 12 are prematurely degraded and inactivated in the digestive tract of the organism, and the coating body 11 and additives of the outer layer structure can be adjusted according to the characteristics of the components of the core body 12 and the target release area.

11: Covering body

12: Core Body

21: Active Ingredients

22: Yeast

23: Prebiotics

Claims (7)

A particle structure containing active ingredient yeast, which comprises: a core body, comprising one or more active ingredients, one kind of yeast and one or more prebiotics; a coating body, covering the outer layer of the core body, to resist The external environment changes, and the core body is protected to maintain its effectiveness. The particulate structure containing yeast as claimed in claim 1, wherein the source of the active ingredient includes animals, plants, microorganisms and the like. The microparticle structure containing yeast as an active ingredient according to claim 1, wherein the yeast is Saccharomyces cerevisiae or a derivative thereof. The active ingredient yeast-containing particulate structure according to claim 1, wherein the encapsulation body comprises polysaccharide derivatives such as glucan, starch, cellulose, cyclodextrin and the like. The particulate structure containing active ingredient yeast according to claim 1, wherein the particulate structure comprises moisture-proofing agent, antioxidant, hygroscopic agent, chelating agent, swelling agent, adhesive and the like. As claimed in claim 1, the active ingredient yeast-containing particulate structure can be used as powder, capsule, powder packet or lozenge. The particulate structure containing the active ingredient yeast as described in claim 1 is dedicated to small animals and pets.

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