TWM595542U - Reagent cartridge - Google Patents

Abstract

A reagent box includes a first positioning part, a second positioning part, and a reagent tank. The second positioning portion is opposite to the first positioning portion in a longitudinal direction, and the shape of the second positioning portion is different from the shape of the first positioning portion. The reagent tanks are arranged along the longitudinal direction and interposed between the first and second positioning portions. The top of each reagent tank is open, and the bottom of each reagent tank is closed.

Description

Reagent cartridge

The present invention relates to an appliance for extracting nucleic acid, especially a reagent cartridge.

As shown in FIG. 1, it is a conventional well plate 1 that can be placed on a biochemical reactor (such as nucleic acid purification equipment, not shown) to perform nucleic acid extraction. The deep well plate 1 has a number arranged in a matrix In the reagent tank 101, the user drops the reagent into the reagent tank 101 manually.

Although such a deep-well plate 1 is bulky and can be stably placed on the biochemical reactor, since the deep-well plate 1 takes up a lot of space, the deep-well plate 1 is only suitable for laboratory use The indoor environment is not easy to carry, and is not suitable for the first-line occasions outside the laboratory, such as the quarantine site of the breeding industry or the forensic site.

In addition, even if only a part of the reagent tank 101 (for example, one row) is used for a small-scale extraction operation, such a deep-well plate 1 can only be discarded after use, which is not environmentally friendly in use.

Therefore, the purpose of the present invention is to provide a reagent cartridge that can overcome at least one disadvantage of the prior art.

Therefore, the new reagent cartridge includes a first positioning part, a second positioning part, and a reagent tank.

The second positioning portion is opposite to the first positioning portion in a longitudinal direction, and the shape of the second positioning portion is different from the shape of the first positioning portion.

The reagent tanks are arranged along the longitudinal direction and interposed between the first and second positioning portions. The top of each reagent tank is open, and the bottom of each reagent tank is closed.

The effect of the present invention is that the design of the first and second positioning parts with different shapes can produce a foolproof installation effect, which helps users to accurately and quickly integrate the first and second positioning parts into an extraction rack In the installation tank, and the new reagent tank is a single row structure design, small size and easy to carry, suitable for the first-line occasions outside the laboratory, in addition, the new model is convenient for users to small Large-scale nucleic acid extraction operations, after use, will not produce unused reagent tank holes, which is quite environmentally friendly in use.

Referring to FIGS. 2, 3 and 4, it is an embodiment of the new reagent cartridge 100. In this embodiment, the reagent cartridge 100 can be installed on an extraction rack 200 to perform nucleic acid extraction in a biochemical reactor 300. The extraction rack 200 has a number of mounting grooves 210 and a number of V-shaped clamping grooves 220. Each mounting groove 210 has a semi-circular front groove portion 211 with a cross-sectional outer contour, and a cross-sectional outer contour Each U-shaped rear groove 212 communicates with each of the front grooves 211 of the respective mounting groove 210.

As shown in FIGS. 5, 6, and 7, the reagent cartridge 100 includes a cartridge body 10, a number of tank bodies 20I, 20II, 20III, 20IV, 20V, 20VI, 20VII, and a release paper 30.

The box body 10 includes a front end wall 11, a rear end wall 12 opposite to the front end wall 11 in a longitudinal direction X, two connected between the front end wall 11 and the rear end wall 13 and being perpendicular to the Side walls 13 spaced apart from each other in the lateral direction Y of the longitudinal direction X, a first reinforcing wall 14 extending along the longitudinal direction X, and spaced apart along the longitudinal direction X and extending along the lateral direction Y between the lateral walls 13 The second reinforcing wall 15 in between, a front holding block 16 provided on the front end wall 11 and protruding forward, and a rear holding block 17 provided on the rear end wall 12 and protruding backward.

The front end wall 11 has an upper wall portion 111 in front of one of the grooves 20I in the longitudinal direction X, and two lower wall portions 112 which are lower than the upper wall portion 11 in a height direction Z, the height direction Z It is perpendicular to the longitudinal direction X and the lateral direction Y.

The first reinforcement wall 14 is connected to the bottom ends of the troughs 20I, 20II, 20III, 20IV, 20V, 20VI, 20Ⅶ, and is connected to the rear end wall 12, and the second reinforcement walls 15 are connected to the first reinforcement The walls 14 are interlaced, and the second reinforcing walls 15 are connected to the bottom ends of the remaining troughs 20II, 20III, 20IV, 20V, 20VI, and 20VII, respectively. The first reinforcing wall 14 and the second reinforcing walls 15 can increase the structural stability of the reagent cartridge 100.

The front grip block 16 and the rear grip block 17 can facilitate the user to take the reagent cartridge 100.

The one of the grooves 20I closest to the front end wall 11 includes an exposed wall 21 exposed outside the front end wall 11 and the side walls 13, the exposed wall 21 being lower than the upper wall portion in the height direction Z 111, the lower wall portions 112 are located on both sides of the exposed wall 21, and the remaining grooves 20II, 20III, 20IV, 20V, 20VI, 20Ⅶ are interposed between the front and rear walls 11, 12 in the longitudinal direction X And between the side walls 13 in the lateral direction Y.

Each tank 20I, 20II, 20III, 20IV, 20V, 20VI, 20Ⅶ defines a reagent tank 22 for filling reagents, and each tank 20I, 20Ⅱ, 20Ⅲ, 20IV, 20V, 20VI, 20Ⅶ The top end of 22 is open, and the bottom end of the reagent tank 22 of each tank 20I, 20II, 20III, 20IV, 20V, 20VI, 20VII is closed.

The release paper 30 is detachably disposed at the top of the cassette body 10, and seals the reagent tanks 22 of the tanks 20I, 20II, 20III, 20IV, 20V, 20VI, 20Ⅶ to seal the tanks 20I, 20II, The reagents in the reagent tanks 22 of 20III, 20IV, 20V, 20VI, and 20VII are torn off the release paper 30 when they are to be used.

The reagent cartridge 100 also has a first positioning portion 40, a second positioning portion 50, a third positioning portion 60, and a fourth positioning portion 70.

In this embodiment, the first positioning portion 40 is formed on the exposed wall 21, and the outer contour of the cross section of the first positioning portion 40 is semicircular.

The second positioning portion 50 is opposite to the first positioning portion 40 in the longitudinal direction X, and the shape of the second positioning portion 50 is different from the shape of the first positioning portion 40. In this embodiment, the second positioning portion 50 is formed by the portions of the side walls 13 adjacent to the rear end wall 12 cooperating with the rear end wall 12, and the outer contour of the cross section of the second positioning portion 50 is U-shaped The reagent tanks 22 of the tanks 20I, 20II, 20III, 20IV, 20V, 20VI, and 20VII are arranged along the longitudinal direction X and interposed between the first and second positioning portions 40, 50.

In this embodiment, the third positioning portion 60 is disposed on the exposed wall 21, and the shape of the third positioning portion 60 is V-shaped. As shown in FIG. 8, the third positioning portion 60 is in the height direction Z The bottom end of the reagent tank 22 of one of the tanks 20I closest to the first positioning unit 40 is farther from the first positioning unit 40.

As shown in FIGS. 5, 6, and 7, in this embodiment, the fourth positioning portion 70 is provided on the rear end wall 12, and the shape of the fourth positioning portion 70 is V-shaped, as shown in FIG. 8, The fourth positioning portion 70 is farther away from the bottom end of the reagent tank 22 of the other tank 20Ⅶ closest to the second positioning portion 50 in the height direction Z than the second positioning portion 50.

Thus, as shown in FIGS. 3, 8 and 9, when the user wants to install the reagent cartridge 100 in one of the mounting grooves 210 of the extraction rack 200, the first and second positioning portions 40 and 50 of different shapes, The user can correctly integrate the first and second positioning portions 40 and 50 into the front and rear groove portions 211 and 212 of the one of the mounting grooves 210 respectively. At this time, the third positioning portion 60 will be embedded in Corresponding to one of the mounting slots 210 of the one of the mounting slots 210, a positioning effect is generated.

Through the above description, the advantages of the new model can be summarized as follows:

1. The new type utilizes the first and second positioning portions 40, 50 of different shapes to produce a foolproof installation, which helps users to correctly and quickly integrate the first and second positioning portions 40, 50 into the The front and rear grooves 211, 212 of one of the mounting grooves 210, and the third positioning portion 60 will be snapped into the one of the grooves 220 to produce a positioning effect to improve the reagent cartridge 100 in the The stability of the nucleic acid extraction operation on the biochemical reactor 300.

2. Compared with the conventional technology, the new tanks 20I, 20II, 20Ⅲ, 20IV, 20V, 20VI, 20Ⅶ are designed in a single row arrangement. The small size of this new type does not occupy space, but it is easy to carry and is quite Applicable to the first-line occasions outside the laboratory, such as the quarantine site of the breeding industry or the forensic site

3. Compared with the conventional technology, the present invention is convenient for the user to carry out small-scale nucleic acid extraction operation, and after use, the hole position of the unused reagent tank 22 will not be left, which is quite environmentally friendly in use.

In summary, the new reagent cartridge is not only foolproof during installation, but also small in size and easy to carry. It is also suitable for the first-line occasions outside the laboratory, so it can really achieve the purpose of new cost.

However, the above are only examples of the new model. When the scope of the new model cannot be limited by this, any simple equivalent changes and modifications made according to the patent application scope and patent specification content of the new model are still regarded as Within the scope of this new patent.

100: reagent cartridge 10: Box 11: front wall 111: upper wall 112: Lower wall 12: rear wall 13: Side wall 14: The first reinforcement wall 15: Second reinforcement wall 16: Front grip block 17: Rear grip block 20Ⅰ: tank body 20Ⅱ: tank body 20Ⅲ: Tank body 20Ⅳ: tank body 20Ⅴ: tank body 20Ⅵ: tank 20Ⅶ: tank 21: exposed wall 22: reagent tank 30: release paper 40: First positioning part 50: Second positioning part 60: Third positioning part 70: Fourth positioning section X: length direction Y: horizontal direction Z: height direction 200: extraction rack 210: mounting slot 211: Front groove 212: Rear groove 220: card slot 300: Biochemical reactor 1: deep well plate 101: reagent tank

Other features and functions of the present invention will be clearly presented in the embodiments with reference to the drawings, in which: Figure 1 is a perspective view of a conventional deep hole plate; FIG. 2 is a perspective view of an embodiment of the novel reagent cartridge installed in a biochemical reactor by an extraction rack; 3 is an exploded perspective view of the embodiment and the extraction rack; Figure 4 is a view similar to Figure 3, but viewed from another angle; 5 is an exploded perspective view of the embodiment; 6 is a view similar to FIG. 5, but viewed from another angle, and remove a release paper of this embodiment; 7 is another perspective view of the embodiment; 8 is a combined cross-sectional view of the embodiment and the extraction rack; and 9 is a cross-sectional view taken along line IX-IX in FIG. 8.

100: reagent cartridge

10: Box

11: front wall

111: upper wall

112: Lower wall

12: rear wall

13: Side wall

16: Front grip block

17: Rear grip block

20 I: tank body

20 Ⅱ: tank body

20Ⅲ: Tank body

20Ⅳ: tank body

20V: tank body

20Ⅵ: tank

20Ⅶ: tank

21: exposed wall

22: reagent tank

30: release paper

40: First positioning part

50: Second positioning part

60: Third positioning part

X: length direction

Y: horizontal direction

Z: height direction

Claims (10)

A reagent cartridge, including: A first positioning section; A second positioning portion opposite to the first positioning portion in a longitudinal direction, the shape of the second positioning portion is different from the shape of the first positioning portion; and Several reagent tanks are arranged along the longitudinal direction and interposed between the first and second positioning parts. The top of each reagent tank is open, and the bottom of each reagent tank is closed. The reagent cartridge according to claim 1, further comprising a cartridge body and a number of tanks, the cartridge body including a front end wall, a rear end wall opposite to the front end wall in the length direction, and two connected to the Side walls spaced from each other between the front end wall and the rear end wall in a lateral direction perpendicular to the length direction, the grooves respectively define the reagent grooves, and one of the grooves closest to the front end wall It includes an exposed wall exposed outside the front end wall and the side walls, the first positioning portion is formed on the exposed wall, and the second positioning portion cooperates with the rear end wall by the portions of the side walls adjacent to the rear end wall As a result, the remaining grooves are interposed between the front and rear walls in the length direction and between the side walls in the lateral direction. The reagent cartridge according to claim 2, wherein the outer contour of the cross section of the first positioning portion is semicircular, and the outer contour of the cross section of the second positioning portion is U-shaped. The reagent cartridge according to claim 3, wherein the front end wall has an upper wall portion located before the one of the tanks in the length direction, and two are lower than the upper wall portion in a height direction and are respectively located In the lower wall portions on both sides of the exposed wall, the height direction is perpendicular to the length direction and the lateral direction, and the exposed wall is lower than the upper wall portion in the height direction. The reagent cartridge according to claim 2, wherein the cartridge body further includes a front grip block disposed on the front end wall and protruding forward, and a rear grip provided on the rear end wall and protruding backward Holding block. The reagent cartridge according to claim 2, wherein the cartridge body further includes a first reinforcing wall extending along the length direction, and a plurality of spaced apart along the length direction and extending between the side walls along the lateral direction Of the second reinforcing wall, the first reinforcing wall is connected to the bottom ends of the troughs and to the rear end wall, the second reinforcing walls are interlaced with the first reinforcing wall, the second reinforcing walls Connect with the bottom ends of the remaining troughs respectively. The reagent cartridge according to claim 1, further comprising a third positioning part which is farther from the first positioning part than the first positioning part in a height direction perpendicular to the length direction The bottom end of one of the reagent tanks. The reagent cartridge according to claim 7, further comprising a fourth positioning portion, the fourth positioning portion is farther away from the second reagent portion closest to the second positioning portion in the height direction than the second positioning portion Of the bottom. The reagent cartridge according to claim 8, wherein the third and fourth positioning portions have a V-shape. The reagent cartridge according to claim 8, further comprising a cartridge body and a number of tanks, the cartridge body including a front end wall, a rear end wall opposite to the front end wall in the length direction, and two connected to the Side walls spaced from each other between the front end wall and the rear end wall and in a transverse direction perpendicular to the length direction and the height direction, the tank bodies respectively define the reagent tanks, and are closest to the front end wall One of the troughs includes an exposed wall exposed outside the front end wall and the side walls, and the remaining troughs are interposed between the front and rear end walls in the length direction, and interposed in the transverse direction Between the equal side walls, the first positioning portion is formed on the exposed wall, the second positioning portion is formed by the portions of the side walls adjacent to the rear end wall cooperating with the rear end wall, and the third positioning portion is disposed on the exposed side The wall, the fourth positioning portion is provided on the rear end wall.

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