TWM590030U - Anti-interference non-invasive blood glucose detection - Google Patents

Abstract

The present invention provides an anti-interference non-invasive blood glucose test, which includes a first electrode, a second electrode, a third electrode, and a fourth electrode made of a conductor exposed outside the housing; and a working circuit; wherein, the first The electrode, the third electrode and the fourth electrode are provided at one end of the casing to form a first probe, and the second electrode is separately provided at the other end of the casing to form a second probe; the first electrode is connected to the second electrode; the third electrode Connected to the fourth electrode; working circuit includes: signal processing module, storage unit, microprocessor, power supply module; the first electrode, the second electrode, the third electrode and the fourth electrode are connected to the signal processing module, micro processing The device is connected to the signal processing module, the storage unit is connected to the microprocessor, and the power module supplies power to each component through the circuit. The new model can reduce external interference, capture more accurate data, and measure more accurate and true blood glucose values.

Description

An anti-interference non-invasive blood glucose test

The present invention relates to the field of medical devices, and specifically relates to an anti-interference non-invasive blood glucose detection.

At present, countries around the world have begun to pay attention to the technical development of non-invasive (no-blood blood) blood glucose detectors, generally using electronic technology to obtain physiological data of the human body through the human skin. Although these known single electronic technologies can see the changes in the skin's electronic signals, it has been found through experiments that these changes are very subtle and extremely susceptible to interference from the external environment. Therefore, the accuracy of the detected data cannot be guaranteed and lacks practical significance.

Moreover, this non-invasive blood glucose test only detects electronic data. Before there is no actual data calibration method, these electronic data lack authenticity and cannot directly calculate the real blood glucose value of the human body. At present, various home blood glucose meters, whether they are non-invasive or blood-binding, claim to be able to detect blood glucose values, and can only actually detect electronic data. It is a scientific scam and its accuracy has an error of greater than ±20%. Taking the user's true blood glucose value as an example, an error of ±20% has been introduced The measured value will fluctuate between 5.2-7.8. Such a large floating range has caused some risk groups that are only high blood sugar to be misdiagnosed as diabetic patients, or some diabetic patients are misdiagnosed as risk groups and delay treatment.

Therefore, there is no effective non-invasive blood glucose detector that can make a real product.

It is not difficult to see that the existing technology still has certain defects.

The technical problem to be solved by the new model is to provide an anti-interference non-invasive blood glucose detection and calculation method, which can reduce external interference and capture more accurate data through the rational design of electrodes and circuits. At the same time, through a scientific calibration method, a more real blood glucose value is measured.

In order to achieve the above purpose, the present invention adopts the following technical solution: an anti-interference non-invasive blood glucose detection, including a first electrode, a second electrode, a third electrode and a fourth electrode composed of conductors exposed outside the housing; And a working circuit; wherein, the first electrode, the third electrode and the fourth electrode are provided at one end of the casing to form a first probe, and the second electrode is separately provided at the other end of the casing to form a second probe; the first electrode and The second electrode is connected to contact two different positions of the human body to form a loop to measure data; the third electrode is connected to the fourth electrode to contact the human body at the first probe to form a loop to measure the first probe and the human body Interference at the contact Among them, the working circuit includes: a signal processing module for filtering and adjusting the data intercepted by each electrode; a storage unit for storing the data of the user's blood test for the first correction; a microprocessor for computing the signal The data obtained by the processing module; the power module, which is used for power supply of all components; the first electrode, the second electrode, the third electrode and the fourth electrode are connected to the signal processing module, and the microprocessor is connected to the signal processing module, The storage unit is connected to the microprocessor, and the power supply module supplies power to each component through the circuit.

Further, the signal processing module includes a signal filtering circuit, a signal amplifying circuit and a conversion circuit; the signal filtering circuit and the signal amplifying circuit are connected to a first electrode and a second electrode, a third electrode and a fourth electrode Two loops; the conversion circuit is connected to the signal amplification circuit, and the microprocessor is connected to the conversion circuit.

Further, a first capacitor and a second capacitor are connected between the signal filtering circuit and the signal amplifying circuit, and are used to store the signal current formed by the loop after being filtered and rectified by the signal filtering circuit.

Further, two middle conductors are respectively provided on the first probe, and a ring conductor is provided on the periphery of the two middle conductors, which serve as the first electrode, the third electrode, and the fourth electrode, respectively.

Further, it also includes a display unit for outputting data processing results; display The unit is connected to the microprocessor and is exposed to the housing.

Further, it also includes an input unit, which is used to input the data of the user's blood test to the storage unit, and the input unit is connected to the microprocessor.

An anti-interference non-invasive blood glucose detection, including the following steps: S01, make the first probe with the electrode and the second probe with the electrode respectively contact different positions of the human body to form a loop, and draw a current to the electrode on the first probe , Detect the electronic data, calculate and store it in the storage unit; S02, then use the hospital blood test to detect the blood glucose value of the user, and store the detected corrected blood glucose value, using the data obtained in step S01 as the correction data Match the corrected blood glucose value; S03. When the blood glucose value needs to be detected, repeat step S01, use the data measured at this time as real-time data, and compare it with the corrected data and corrected blood glucose value obtained at step S02 to obtain the user at that time Instant blood sugar level.

Further, in the steps S02 to S03, the current I ₁ drawn by the first electrode and the current I ₁ +I ₂ drawn by the first electrode and the third electrode are stored in the first capacitor and the second capacitor respectively , And then discharge the electricity of the first capacitor and the second capacitor separately to obtain the electronic data of the measurement circuit and the deduction circuit respectively.

Further, whenever steps S01 to S04 are executed, the step S02 is repeatedly executed at a certain time interval before step S03, and the data with the most repetitions is taken as the electronic data of the measurement loop.

Further, whenever steps S01 to S04 are executed, after stimulating the user for 0.8-1.1 seconds in step S01, the steps S02 to S04 are repeated multiple times to obtain stable and high-precision electronic data.

Further, before all the steps, there is a pre-processing step S00, which has the following steps, S001, classifying blood glucose values of different levels according to the severity of the blood glucose level; S002, on the basis of standard blood glucose values of different classifications Calculate the interval value of each category according to the positive and negative tolerances, and establish a database of numerical intervals of different categories; compare the real-time blood glucose value obtained in step S06 with the database created in step S002 to obtain the user's status.

The anti-interference non-invasive blood glucose detection provided by the present invention, by designing multiple electrodes to form multiple circuits, can reduce the interference of the external environment during the measurement process by means of data deduction and make the detection data more accurate. And the design of the circuit has the function of signal amplification and filtering, which further improves the sensitivity and accuracy of data detection.

The present invention also provides an anti-interference non-invasive blood glucose detection, which adopts a more advanced multi-electrode measurement method to avoid interference and obtain more accurate data. And has a scientific data calibration method, so as to match the true and accurate blood glucose value.

1‧‧‧Housing

2‧‧‧First probe

3‧‧‧Second Probe

4‧‧‧First electrode

5‧‧‧Second electrode

6‧‧‧third electrode

7‧‧‧The fourth electrode

8‧‧‧Display screen

9‧‧‧Processing module

10‧‧‧storage screen

11‧‧‧Microprocessor

12‧‧‧Power Module

13‧‧‧Signal filter circuit

14‧‧‧Signal amplifier circuit

15‧‧‧ Conversion circuit

16‧‧‧ First capacitor

17‧‧‧Second capacitor

In order to more clearly explain the new embodiment or the technical solution in the prior art, the following will briefly introduce the drawings required in the description of the embodiment or the prior art. Obviously, the drawings in the following description are only For some new embodiments, for those of ordinary skill in the art, without paying any creative work, other drawings may be obtained based on these drawings.

FIG. 1 is a schematic diagram of an external structure of an anti-interference non-invasive blood glucose detection provided by the new model.

Figure 2 is a schematic diagram of the internal circuit structure.

Figure 3 is a schematic diagram of the circuit formed by the electrode and the human body.

In order to make the purpose, technical solutions and advantages of the new embodiment clearer, the technical solutions in the new embodiment will be described clearly and completely in conjunction with the new embodiment and the drawings. It should be noted that the described embodiments are only a part of the embodiments of the present invention, but not all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without making creative efforts fall within the scope of protection of the present invention.

Example one

Please refer to FIGS. 1-2, the new embodiment of the present invention provides a non-intrusive anti-interference Blood glucose detection, including a first electrode 4, a second electrode 5, a third electrode 6, and a fourth electrode 7 made of a conductor exposed outside the housing 1; and a working circuit; wherein, the first electrode 4, the third electrode 6 and the fourth electrode 7 are provided at one end of the housing 1 to form a first probe 2, the second electrode 5 is separately provided at the other end of the housing 1 to form a second probe 3; the first electrode 4 is connected to the second electrode 5 , Used to contact two different positions of the human body to form a loop to measure data; the third electrode 6 is connected to the fourth electrode 7 for contacting the human body at the first probe 2 to form a loop to measure the relationship between the first probe 2 and the human body Interference data at the contact point; among them, the working circuit includes: a signal processing module 9 for filtering and adjusting the data intercepted by each electrode; a storage unit 10 for storing the data of the user's blood test for the first correction; micro-processing 11 is used to process the data obtained by the signal processing module 9, and the power module 12 is used to supply power to all components; the first electrode 4, the second electrode 5, the third electrode 6 and the fourth electrode 7 and the signal processing The module 9 is connected, the microprocessor 11 is connected to the signal processing module 9, the storage unit 10 is connected to the microprocessor 11, and the power module 12 supplies power to each component through the circuit.

Unlike the existing technology, this new model does not simply use two electrodes to form a loop with the human body to detect blood glucose data, but uses four electrodes distributed on two probes to form multiple circuits with the human body to achieve the reduction of interference data. Operational functions make the inspection data more accurate.

The working principle of each electrode is shown in Figure 3. The four electrodes are respectively arranged on two probes and contact different positions of the human body. Preferably, the first probe 2 contacts the palm of a person and the second probe 3 contacts the thumb of the other hand. Among them, the first electrode 4 provided on the first probe 2 and the second electrode 5 provided on the second probe 3 form a loop, which can be energized to detect electronic data without intrusion. However, when the probe is in contact with human skin, it is easily affected by external factors such as contact effectiveness, humidity, and foreign objects, causing interference near the contact and affecting the stability and accuracy of the data. Therefore, in the present invention, a third electrode 6 and a fourth electrode 7 are provided at the first probe 2 to form a loop, and a deduction loop is formed at the contact point of the palm, which is specially used to detect and reduce external interference near the contact point.

In addition to the design of the electrode, the present invention also provides a storage unit 10 in the circuit, which is used to store the real blood glucose value measured by the user by blood drawing and the electronic data measured by the electrode, so as to realize the calibration of the data. Therefore, the present invention does not simply measure electronic signals. The specific calibration method will be described in detail in the blood glucose detection method below.

It should be noted that various buttons, switches and the like may be installed on the housing 1 to realize various control functions. However, these components are not the technical focus of this new model and are not much related to the technical solution, and will not be repeated in this new model. In addition, this structure is omitted in the drawings of the specification.

Preferably, the signal processing module 9 includes a signal filter circuit 13, a signal amplifying circuit 14 and a conversion circuit 15; the signal filter circuit 13 and the signal amplifying circuit 14 are connected to the first electrode 4 and the second electrode 5 by the first Three electrodes 6 and fourth electrodes 7 On the two circuits formed; the conversion circuit 15 is connected to the signal amplifying circuit 14, and the microprocessor 11 is connected to the conversion circuit 15.

The signal amplifying circuit 14 is used to receive and amplify the electrical signals transmitted by the electrodes, so that the weak electrical signals are more sensitive after amplification. The signal filtering circuit 13 is used for rectifying and filtering noise to obtain a clean signal. The conversion circuit 15 is used to convert the analog signal into a digital signal.

As a further preference, a first capacitor 16 and a second capacitor 17 are connected between the signal filtering circuit 13 and the signal amplifying circuit 14 for storing the signal current formed by the loop after being filtered and rectified by the signal filtering circuit 13 and stored therein .

For the distribution and structure of the electrodes on the first probe 2, the following structure is preferably adopted. The first probe 2 is respectively provided with two middle conductors, and a ring conductor is provided on the periphery of the two middle conductors, serving as the first electrode 4, the third electrode 6 and the fourth electrode 7, respectively.

It should be noted that which of the three conductors corresponds to the first electrode 4, the third electrode 6, or the fourth electrode 7 is not actually the technical focus of the present invention. In general, it is preferable to use a ring conductor as the third electrode 6 and two middle conductors as the first electrode 4 and the fourth electrode 7, respectively. However, a ring-shaped conductor may be used as the first electrode 4 and two middle conductors may be used as the third electrode 6 and the fourth electrode 7, respectively. The main purpose of setting three electrodes on the first probe 2 is to eliminate contact interference and improve data acquisition accuracy. Therefore, the arrangement of the first electrode 4, the third electrode 6, and the fourth electrode 7 is not excessively limited without departing from this design goal.

Preferably, it also includes a display unit 8 for outputting the results of data processing; The display unit 8 is connected to the microprocessor 11 and is exposed to the housing 1. It also includes an input unit for inputting the data of the user's blood test to the storage unit 10, and the input unit is connected to the microprocessor 11.

Of course, it is not excluded that the present invention itself does not have the display unit 8 and displays the result by means of signal transmission to an external display device. Similarly, it is also possible that the present invention does not have an input unit itself, and it is also a feasible solution to log data to the storage unit 10 by means of wireless or wired transmission by external devices.

The present invention provides an anti-interference non-invasive blood glucose detection. By designing multiple electrodes to form multiple circuits, the interference of the external environment during the detection process can be reduced by data deduction, so that the detected data is more accurate. And the design of the circuit has the function of signal amplification and filtering, which further improves the sensitivity and accuracy of data detection.

Example 2

This embodiment details an anti-interference non-invasive blood glucose detection, and its essence is also the working process of the non-invasive anti-interference blood glucose detector described in the first embodiment.

An anti-interference non-invasive blood glucose detection, including the following steps: S01, make the first probe with the electrode and the second probe with the electrode respectively contact different positions of the human body to form a loop, and draw a current to the electrode on the first probe , Detect the electronic data, calculate and store it in the storage unit; S02, then use the hospital blood test to detect the user's blood glucose value, and store the corrected blood glucose value, using the data obtained in step S01 as the school The positive data matches the corrected blood glucose value; S03. When the blood glucose value needs to be detected, repeat step S01, use the data measured at that time as real-time data, and compare it with the corrected data and corrected blood glucose value obtained at step S02 to obtain the time The user's real-time blood glucose value.

This method advocates calibration and matching calculation with the real blood glucose value measured by blood drawing. Therefore, the detection of blood glucose value is not just a simple electronic data, but a value that actually matches the blood glucose value of the human body. This method is scientific and reasonable, and has high accuracy, which helps to accurately determine the blood glucose situation of the user and will not delay the diagnosis and treatment.

As mentioned above, simply intercepting electronic data itself has no real effect on blood glucose testing, and no real blood glucose value is obtained. Therefore, the present invention devises a calibration process, that is, step S02 needs to be implemented, and the user's real blood glucose value is measured by way of blood sampling in the hospital and input into the blood glucose meter. Before inputting the blood glucose data, non-intrusive detection through normal electrodes is used to intercept high-precision electronic data, which can be matched with the real blood glucose value measured in step S02 to achieve calibration. This process is actually a learning process carried out by the blood glucose detector according to the actual physical condition of the user. Through calibration, a data matching system can be constructed to know the blood glucose value corresponding to different electronic data. Even a database can be established to match the corresponding blood glucose level to inform the user of his physical condition.

It is generally recommended that calibration be performed at regular intervals to maintain the accuracy of the data Certainty, because changes in blood glucose levels will change over time and changes in body state. For diabetics, it is generally 1.5-3 months as a course of treatment, so it is scientific and reasonable to calibrate the blood test blood glucose at intervals.

The process of calibrating the blood drawn blood glucose value is an important technical breakthrough of the new method. The electronic data detected by electronic methods, even if the accuracy is high, is only a set of electronic data, not real blood glucose data. Even the widely used blood-gathering blood glucose meter at home is easily affected by factors such as impurities, blood concentration, and whether the blood reacts adequately in the instrument, leading to distortion of blood glucose values. The blood glucose value measured by the instrument is accurate only when the method of blood sampling in the hospital is used to detect the blood glucose value and the real blood glucose value is obtained for comparison and calibration.

For example, in the previously measured electronic data, the current value is 100 milliamperes, and the blood glucose value corresponding to the electronic data is known. In the electronic data measured after that, the current value becomes 150 milliamperes, then the corresponding blood glucose value at the time of occurrence can be calculated.

More specifically, in the steps S02 to S03, the current I ₁ drawn by the first electrode 4 and the current I ₁ +I ₂ drawn by the first electrode 4 and the third electrode 6 are stored in the first capacitor 16 and the second capacitor 17, and then discharge the electricity of the first capacitor 16 and the second capacitor 17, respectively, to obtain the electronic data of the measurement circuit and the deduction circuit.

Each time the electrode is not invasively detected, the data can be repeatedly intercepted in certain steps, and valid data can be selected for calculation to further improve the accuracy of the detected data. Preferred Whenever steps S01 to S04 are executed, the step S02 is repeatedly executed multiple times at a certain time interval before step S03, and the data with the most repetitions is taken as the electronic data of the measurement loop.

For example, the first electrode 4 emits a minute current I ₁ to the human body every 0.1 seconds, and the third electrode 6 emits a minute current I ₂ to the human body every 0.5 seconds. Then, 0.5 seconds ago, the first electrode 4 performed current energization detection multiple times (that is, the step S02 was repeatedly performed multiple times), and the data with the most repetitions could be captured as electronic data of the measurement loop. At the 0.5th second, the first electrode 4 and the third electrode 6 draw currents at the same time, and the current value used in the calculation is the sum of I ₁ +I ₂ .

It has been found through experiments that after the first probe 2 comes into contact with the human body contacts, it is not immediately possible to energize to obtain stable electronic data, but to stimulate the user for a certain time before the data tends to be stable. Therefore, preferably, whenever steps S01 to S04 are executed, after stimulating the user for 0.8-1.1 seconds in step S01, steps S02 to S04 are executed again, which is beneficial to obtain stable electronic data.

Furthermore, in addition to waiting for the data to stabilize, it is also possible to obtain valid data by repeatedly intercepting the data after the electrode contacts the contact of the human body. Preferably, whenever steps S01 to S04 are executed, steps S02 to S04 are repeatedly executed to obtain the high-precision data with the most repetitions.

For example, after the electrode comes into contact with the contact of the human body, stable data appears in 0.8-1.1 seconds. Then intercept data in the interval of 0.8-1.1 seconds, and restart multiple times in this Intercept multiple data in the time interval and grab the valid data.

For further improvement of the measurement calculation method, before all steps, there may be a pre-processing step S00, which has the following steps, S001, according to the severity of blood glucose level to classify different levels of blood glucose levels; S002, in different classifications Based on the standard blood glucose value, the interval values of each category are calculated according to the positive and negative tolerances, and a database of numerical intervals of different categories is established; the real-time blood glucose value obtained in step S06 is compared with the database created in step S002 to obtain The state of the user.

For example, according to the severity of blood sugar level, it can be roughly divided into:

The tolerance value can be selected to be ±10%, and the interval value is determined:

The instant blood glucose value measured in step S06 can be directly compared with the blood glucose value interval, and immediately know which state the user is in, which is convenient for the doctor to track the treatment and adjust the medication. Since the electronic signal is very weak, everyone's response to the electronic will also be different. By correcting the type of the user's landing first, and then supplementing with a certain percentage of probability errors to narrow the range to approximate accuracy.

The above-mentioned numerical interval distribution is just an application example, even if the numerical interval distribution is different, or further subdivided, it belongs to the concept of the new type.

1‧‧‧Housing

2‧‧‧First probe

3‧‧‧Second Probe

4‧‧‧First electrode

5‧‧‧Second electrode

6‧‧‧third electrode

7‧‧‧The fourth electrode

8‧‧‧Display screen

Claims (6)

A non-invasive anti-interference blood glucose detector, which is characterized by comprising a first electrode, a second electrode, a third electrode and a fourth electrode made of a conductor exposed outside the casing; and a working circuit; wherein, the first The electrode, the third electrode and the fourth electrode are provided at one end of the casing to form a first probe, and the second electrode is separately provided at the other end of the casing to form a second probe; the first electrode is connected to the second electrode for contact Two different positions of the human body form a loop to measure the data; the third electrode is connected to the fourth electrode to contact the human body at the first probe to form a loop to measure the interference data at the contact point between the first probe and the human body; , The working circuit includes: a signal processing module for filtering and adjusting the data intercepted by each electrode; a storage unit for storing the data of the user's blood test for the first correction; a microprocessor for the signal processing module for arithmetic processing Obtained data; power module for power supply of all components; the first electrode, the second electrode, the third electrode and the fourth electrode are connected to the signal processing module, the microprocessor is connected to the signal processing module, and the storage unit is connected to The microprocessor is connected, and the power module supplies power to each component through the circuit. The non-invasive anti-interference blood glucose detector according to claim 1, characterized The signal processing module includes a signal filtering circuit, a signal amplifying circuit and a conversion circuit; the signal filtering circuit and the signal amplifying circuit are connected to two parts composed of a first electrode and a second electrode, and a third electrode and a fourth electrode On the loop; the conversion circuit is connected to the signal amplification circuit, and the microprocessor is connected to the conversion circuit. The non-invasive anti-interference blood glucose detector according to claim 2, characterized in that: a first capacitor and a second capacitor are connected between the signal filtering circuit and the signal amplifying circuit for signal current formed by the loop, Stored in the signal filter circuit after filtering and rectification. The non-invasive anti-interference blood glucose detector according to claim 1, wherein the first probe is provided with two middle conductors respectively, and a ring conductor is provided around the two middle conductors as the first electrodes , The third electrode and the fourth electrode. The non-invasive anti-interference blood glucose detector according to claim 1, further comprising a display unit for outputting the results of data processing; the display unit is connected to the microprocessor and is exposed to the casing. The non-invasive anti-interference blood glucose detector according to claim 1, further comprising an input unit for inputting the data of the user's blood test to the storage unit, and the input unit is connected to the microprocessor.

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