TWI860281B - 廣效型抗病毒治療的組合物及方法 - Google Patents

廣效型抗病毒治療的組合物及方法 Download PDF

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Publication number
TWI860281B
TWI860281B TW107136527A TW107136527A TWI860281B TW I860281 B TWI860281 B TW I860281B TW 107136527 A TW107136527 A TW 107136527A TW 107136527 A TW107136527 A TW 107136527A TW I860281 B TWI860281 B TW I860281B
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Taiwan
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virus
mers
cov
cells
viral
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TW107136527A
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English (en)
Chinese (zh)
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TW201927293A (zh
Inventor
碩峰 袁
福和 陳
軒 朱
耀南 劉
國勇 袁
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香港商港大科橋有限公司
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW107136527A 2017-10-18 2018-10-17 廣效型抗病毒治療的組合物及方法 TWI860281B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762573933P 2017-10-18 2017-10-18
US62/573,933 2017-10-18

Publications (2)

Publication Number Publication Date
TW201927293A TW201927293A (zh) 2019-07-16
TWI860281B true TWI860281B (zh) 2024-11-01

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Family Applications (1)

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TW107136527A TWI860281B (zh) 2017-10-18 2018-10-17 廣效型抗病毒治療的組合物及方法

Country Status (6)

Country Link
US (1) US12213955B2 (enExample)
EP (1) EP3697404B1 (enExample)
JP (1) JP7466907B2 (enExample)
CN (1) CN111886008B (enExample)
TW (1) TWI860281B (enExample)
WO (1) WO2019079339A1 (enExample)

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WO2018089306A1 (en) 2016-11-10 2018-05-17 Oyagen, Inc. Methods of treating and inhibiting ebola virus infection
WO2020258159A1 (en) * 2019-06-27 2020-12-30 Guangdong Oppo Mobile Telecommunications Corp., Ltd. Method and device for indicating spatial relation information
US11738025B2 (en) 2020-02-04 2023-08-29 Oyagen, Inc. Method for treating coronavirus infections
MX2022011111A (es) * 2020-03-08 2023-03-02 Humanigen Inc Métodos para tratar infección de coronavirus y lesión pulmonar inducida por inflamación resultante.
US11628165B1 (en) * 2020-03-25 2023-04-18 Helen Feng Method of boosting immune system against viral infection
ES2862462B2 (es) * 2020-04-06 2023-04-27 Servicio Andaluz De Salud Compuestos para la profilaxis y/o el tratamiento del sindrome de dificultad respiratoria aguda
WO2021211738A1 (en) * 2020-04-15 2021-10-21 Sanford Burnham Prebys Medical Discovery Institute Methods and compositions for antiviral treatment
WO2021226479A1 (en) * 2020-05-07 2021-11-11 The Regents Of The University Of California Inhaled statins for treatment of viral respiratory diseases
CN116033894A (zh) * 2020-05-22 2023-04-28 卡洛斯·阿尔贝托·里维罗斯 用于减少气道粘膜中的病毒复制的系统、方法和药物使用
WO2021249240A1 (zh) * 2020-06-11 2021-12-16 养生堂有限公司 Palovarotene在抗hbv病毒治疗中的用途
WO2022006446A1 (en) * 2020-07-02 2022-01-06 The Uab Research Foundation Compositions and methods of treating conditions
CN112390731B (zh) * 2020-11-16 2022-11-25 成都大学 一种具有多靶点的维甲酸类衍生物及其制备方法与应用
US11998562B2 (en) 2021-01-25 2024-06-04 University Of South Florida Ophthalmological formulations for the prevention of a coronavirus infection
JP2024504728A (ja) 2021-01-26 2024-02-01 サイトケアズ （シャンハイ） インコーポレイテッド キメラ抗原受容体（ｃａｒ）構築物およびｃａｒ構築物を発現するｎｋ細胞
US20220378727A1 (en) * 2021-05-14 2022-12-01 The University Of Hong Kong Dry powder formulations of tamibarotene for pulmonary and intranasal delivery
CN116891497B (zh) * 2022-04-02 2025-12-16 上海旭成医药科技有限公司 视黄酸受体激动剂、其制备方法、中间体、药物组合物和应用
CN119013012A (zh) * 2022-04-28 2024-11-22 国立大学法人东海国立大学机构 用于治疗伴随有舒张障碍的心力衰竭的药物组合物
CN119454680B (zh) * 2024-12-06 2025-06-17 华南农业大学 贝沙罗汀在制备抗prrsv或治疗猪蓝耳病的药物中的应用
CN121177272A (zh) * 2025-11-10 2025-12-23 北京市农林科学院 化合物am580在预防或治疗塞内卡病毒病中的用途

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WO2005120479A1 (en) * 2004-06-09 2005-12-22 Gpc Biotech Ag Use of selenium or a selenium salt and a retinoid acid or a retinoid in the treatment of viral hepatitis c
WO2014079709A1 (en) * 2012-11-23 2014-05-30 Ab Science Use of small molecule inhibitors/activators in combination with (deoxy)nucleoside or (deoxy)nucleotide analogs for treatment of cancer and hematological malignancies or viral infections
CN106572663A (zh) * 2014-03-10 2017-04-19 康奈尔大学 用于头颈癌的联合疗法

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US7341717B2 (en) * 2001-04-13 2008-03-11 Gpc Biotech Ag Therapeutic targets for treatment of HCV infections, methods of treating HCV infections and compounds useful therefor
CA2509955A1 (en) * 2002-11-29 2004-06-17 Gpc Biotech Ag Formulations useful against hepatitis c virus infections
EP1886685A1 (en) 2006-08-11 2008-02-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods, uses and compositions for modulating replication of hcv through the farnesoid x receptor (fxr) activation or inhibition
JP2010516702A (ja) 2007-01-18 2010-05-20 エヴォルヴァ エスアー 置換１，３−ジオキサンのプロドラッグおよびそれらの使用
CN104662036B (zh) 2012-04-25 2018-11-09 华辉安健（北京）生物科技有限公司 乙肝肝炎病毒功能性受体的组成以及相关应用
MX2016010699A (es) * 2014-02-18 2017-10-11 Children's Hospital Los Angeles Composiciones y metodos para tratar neutropenia.
WO2018054891A1 (en) * 2016-09-20 2018-03-29 Ruprecht-Karls-Universität Compounds and combinations thereof for preventing and/or treating hbv and/or hdv infections

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005120479A1 (en) * 2004-06-09 2005-12-22 Gpc Biotech Ag Use of selenium or a selenium salt and a retinoid acid or a retinoid in the treatment of viral hepatitis c
WO2014079709A1 (en) * 2012-11-23 2014-05-30 Ab Science Use of small molecule inhibitors/activators in combination with (deoxy)nucleoside or (deoxy)nucleotide analogs for treatment of cancer and hematological malignancies or viral infections
CN106572663A (zh) * 2014-03-10 2017-04-19 康奈尔大学 用于头颈癌的联合疗法

Also Published As

Publication number Publication date
EP3697404A1 (en) 2020-08-26
EP3697404B1 (en) 2025-03-26
US12213955B2 (en) 2025-02-04
WO2019079339A1 (en) 2019-04-25
EP3697404A4 (en) 2021-07-21
JP2021500400A (ja) 2021-01-07
CN111886008A (zh) 2020-11-03
JP7466907B2 (ja) 2024-04-15
TW201927293A (zh) 2019-07-16
CN111886008B (zh) 2024-05-31
US20200338032A1 (en) 2020-10-29

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