TWI799842B - 核酸的檢測方法及寡核苷酸探針 - Google Patents

核酸的檢測方法及寡核苷酸探針 Download PDF

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Publication number
TWI799842B
TWI799842B TW110114450A TW110114450A TWI799842B TW I799842 B TWI799842 B TW I799842B TW 110114450 A TW110114450 A TW 110114450A TW 110114450 A TW110114450 A TW 110114450A TW I799842 B TWI799842 B TW I799842B
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TW
Taiwan
Prior art keywords
detecting
nucleic acid
oligonucleotide probe
oligonucleotide
probe
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TW110114450A
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English (en)
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TW202223390A (zh
Inventor
岡部綾子
中社彩香
法木左近
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日商日華化學股份有限公司
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Publication of TW202223390A publication Critical patent/TW202223390A/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
TW110114450A 2020-04-22 2021-04-22 核酸的檢測方法及寡核苷酸探針 TWI799842B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020076369 2020-04-22
JP2020-076369 2020-04-22

Publications (2)

Publication Number Publication Date
TW202223390A TW202223390A (zh) 2022-06-16
TWI799842B true TWI799842B (zh) 2023-04-21

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ID=78269139

Family Applications (1)

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TW110114450A TWI799842B (zh) 2020-04-22 2021-04-22 核酸的檢測方法及寡核苷酸探針

Country Status (6)

Country Link
US (1) US20230193398A1 (zh)
EP (1) EP4141115A4 (zh)
JP (1) JPWO2021215428A1 (zh)
CN (1) CN115803462A (zh)
TW (1) TWI799842B (zh)
WO (1) WO2021215428A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113025611B (zh) * 2021-03-16 2022-06-21 华中农业大学 π-FISH定位单分子的探针组合物及其在核酸原位检测中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104803865A (zh) * 2004-12-22 2015-07-29 Ambrx公司 含有非天然氨基酸和多肽的组合物、涉及非天然氨基酸和多肽的方法以及其用途
CN105263627A (zh) * 2013-01-18 2016-01-20 生米公司 分析设备

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5582985A (en) * 1994-08-05 1996-12-10 The Regents Of The University Of California Detection of mycobacteria
EP1105539A2 (en) * 1998-08-21 2001-06-13 Naxcor Assays using crosslinkable immobilized nucleic acids
EP1313881A2 (en) * 2000-06-06 2003-05-28 TM Bioscience Corporation Capture moieties for nucleic acids and uses thereof
CA2763321C (en) 2009-05-29 2018-10-16 Ventana Medical Systems, Inc. Methods of scoring gene copy number in a biological sample using in situ hybridization
EP2292633A1 (en) * 2009-09-08 2011-03-09 Humboldt Universität zu Berlin Probes comprising fluorescent artificial nucleobases and use thereof for detection of single base alteration
US8658780B2 (en) * 2010-05-18 2014-02-25 California Institute Of Technology Triggered covalent probes for imaging and silencing genetic expression
CA2908379C (en) 2013-03-28 2021-03-30 Japan Advanced Institute Of Science And Technology Photoresponsive nucleotide analogue having photocrosslinking ability
JP2015073523A (ja) * 2013-10-11 2015-04-20 国立大学法人 東京大学 核酸の検出方法、検出プローブ、マイクロアレイ、核酸検出キット、核酸‐検出プローブ‐捕捉プローブ複合体、核酸固定化担体、及び流体デバイス
JP2016145299A (ja) 2015-02-09 2016-08-12 日立化成株式会社 導電材料及びそれを用いた導電体
JP6781975B2 (ja) 2016-05-26 2020-11-11 国立大学法人北陸先端科学技術大学院大学 アンチジーン法用光応答性人工核酸プローブ
JP6920689B2 (ja) 2017-07-26 2021-08-18 日華化学株式会社 可視光域で光架橋可能な光応答性ヌクレオチドアナログ

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104803865A (zh) * 2004-12-22 2015-07-29 Ambrx公司 含有非天然氨基酸和多肽的组合物、涉及非天然氨基酸和多肽的方法以及其用途
CN105263627A (zh) * 2013-01-18 2016-01-20 生米公司 分析设备

Also Published As

Publication number Publication date
EP4141115A1 (en) 2023-03-01
CN115803462A (zh) 2023-03-14
US20230193398A1 (en) 2023-06-22
WO2021215428A1 (ja) 2021-10-28
JPWO2021215428A1 (zh) 2021-10-28
EP4141115A4 (en) 2024-09-11
TW202223390A (zh) 2022-06-16

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