TWI797787B - Device for controlling raman spectrometer - Google Patents

Device for controlling raman spectrometer Download PDF

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TWI797787B
TWI797787B TW110138976A TW110138976A TWI797787B TW I797787 B TWI797787 B TW I797787B TW 110138976 A TW110138976 A TW 110138976A TW 110138976 A TW110138976 A TW 110138976A TW I797787 B TWI797787 B TW I797787B
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block
mode
analysis level
priority analysis
mode module
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TW202317949A (en
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張惟誠
徐俊義
莊學誠
王康
吳金隆
劉俊宏
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炳碩生醫股份有限公司
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Abstract

A device for controlling Raman spectrometer is provided. The device includes an image capturing and analysis unit, a processing unit, a human-machine interface unit, and a carrier control unit. The image capturing and analysis unit is used to capture image information of a subject to be tested, and to divide the image information into a plurality of blocks each having corresponding block information. The processing unit is electrically connected to the image capturing and analysis unit. The processing unit compares one of the block information with a predetermined range of values or threshold of image information to determine whether or not the corresponding block has a first priority. The human-machine interface unit is electrically connected to the image capturing and analysis unit and the processing unit. The human-machine interface unit receives a user input for the block having the first priority so as to record whether or not the block with the first priority has a second priority. The carrier control unit is electrically connected to the human-machine interface unit, and controls a movement of the subject to be tested according to the block having the second priority, so as to enable the block having the second priority to be detected by the Raman spectroscopy.

Description

用於控制拉曼光譜儀的裝置Apparatus for controlling the Raman spectrometer

本發明涉及一種控制裝置,特別是涉及一種用於控制拉曼光譜儀的裝置。The invention relates to a control device, in particular to a device for controlling a Raman spectrometer.

現行主要微生物檢測技術包含生化檢測、基質輔助雷射脫附游離飛行時間(matrix-assisted laser desorption ionization time-of-flight,MALDI-TOF)質譜檢測及拉曼光譜檢測等。生化檢測需長時間的微生物培養,且不同微生物可能需要特定生物反應方法進行鑑定,無法達到直接、快速且準確的微生物檢測。MALDI-TOF質譜檢測應用待測微生物不同蛋白質樣本經離子化後在真空飛行管中產生蛋白質的質量/電荷比圖譜進行微生物鑑定,雖較生化檢測快速,但不同微生物可能具有類似的蛋白質圖譜而影響其鑑別準確率;此外, MALDI-TOF質譜儀設備昂貴,運作環境要求嚴苛,且後續使用耗材及維護費用高,限制其用於微生物檢測之廣泛性。The current main microbial detection technologies include biochemical detection, matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry detection and Raman spectroscopy detection. Biochemical detection requires long-term microbial cultivation, and different microorganisms may require specific biological reaction methods for identification, which cannot achieve direct, rapid and accurate microbial detection. MALDI-TOF mass spectrometry detection uses the mass/charge ratio spectrum of the protein produced in the vacuum flight tube after ionization of different protein samples of the microorganisms to be tested for microbial identification. Although it is faster than biochemical detection, different microorganisms may have similar protein patterns and affect Its identification accuracy; in addition, MALDI-TOF mass spectrometer equipment is expensive, the operating environment is strict, and the subsequent use of consumables and maintenance costs are high, which limits its extensiveness for microbial detection.

拉曼光譜儀相較MALDI-TOF質譜儀來說,具有設備成本低及環境要求較簡單等優點,且適用於檢測廣泛的微生物種類(例如細菌、真菌、病毒等)。再者,隨著人工智慧的影像辨識功能日益強大,將其與拉曼光譜儀檢測結果結合,可精準快速的鑑定微生物種類,提供後續臨床診斷及治療的指引。Compared with MALDI-TOF mass spectrometer, Raman spectrometer has the advantages of low equipment cost and simpler environmental requirements, and is suitable for detecting a wide range of microorganisms (such as bacteria, fungi, viruses, etc.). Furthermore, as the image recognition function of artificial intelligence becomes more and more powerful, combining it with the detection results of Raman spectroscopy can accurately and quickly identify microbial species and provide guidance for subsequent clinical diagnosis and treatment.

本發明提供一種用於控制拉曼光譜儀的裝置,藉以強化拉曼光譜儀的控制。The invention provides a device for controlling a Raman spectrometer, thereby strengthening the control of the Raman spectrometer.

為了解決上述的技術問題,本發明所採用的其中一技術方案是提供一種用於控制拉曼光譜儀的裝置,其包括一影像擷取分析單元、一處理單元、一人機介面單元以及一載物控制單元。影像擷取分析單元用於獲取一待測物的一影像資訊,並將影像資訊分為多個區塊,每一區塊具有對應的一區塊資訊。處理單元電性連接所述影像擷取分析單元。處理單元將其中一區塊資訊與一預定影像資訊數值範圍或門檻值比對以決定對應的區塊是否具有第一優先分析等級。人機介面單元電性連接影像擷取分析單元及處理單元。人機介面單元針對具有第一優先分析等級的各個區塊分別接收一使用者輸入,以記錄各個區塊是否具有第二優先分析等級。載物控制單元電性連接所述人機介面單元。載物控制單元針對具有第二優先分析等級的區塊控制待測物之位置,並使具有第二優先分析等級的區塊進行拉曼光譜檢測。In order to solve the above-mentioned technical problems, one of the technical solutions adopted by the present invention is to provide a device for controlling a Raman spectrometer, which includes an image capture and analysis unit, a processing unit, a man-machine interface unit, and a load control unit unit. The image capturing and analyzing unit is used to acquire an image information of an object under test, and divide the image information into a plurality of blocks, and each block has a corresponding piece of block information. The processing unit is electrically connected to the image capture and analysis unit. The processing unit compares one of the block information with a predetermined value range or threshold value of the image information to determine whether the corresponding block has the first priority analysis level. The man-machine interface unit is electrically connected to the image capture analysis unit and the processing unit. The man-machine interface unit respectively receives a user input for each block with the first priority analysis level to record whether each block has the second priority analysis level. The load control unit is electrically connected to the man-machine interface unit. The load control unit controls the position of the object to be tested for the block with the second priority analysis level, and makes the block with the second priority analysis level perform Raman spectrum detection.

本發明的其中一有益效果在於,本發明所提供的用於控制拉曼光譜儀的裝置,其能通過“系統自動比對以決定對應的區塊是否具有第一優先分析等級,以及使用者輸入確認各個區塊是否具有第二優先分析等級”的技術方案,以加強使用者與拉曼光譜儀之間的人機互動,並提升拉曼光譜儀的控制,減少量測時間及優化檢測結果。One of the beneficial effects of the present invention is that the device for controlling the Raman spectrometer provided by the present invention can determine whether the corresponding block has the first priority analysis level through "system automatic comparison, and user input confirmation Whether each block has a second priority analysis level" technical solution to strengthen the human-computer interaction between the user and the Raman spectrometer, and improve the control of the Raman spectrometer, reduce the measurement time and optimize the detection results.

為使能更進一步瞭解本發明的特徵及技術內容,請參閱以下有關本發明的詳細說明與圖式,然而所提供的圖式僅用於提供參考與說明,並非用來對本發明加以限制。In order to further understand the features and technical content of the present invention, please refer to the following detailed description and drawings related to the present invention. However, the provided drawings are only for reference and description, and are not intended to limit the present invention.

以下是通過特定的具體實施例來說明本發明所公開有關“用於控制拉曼光譜儀的裝置”的實施方式,本領域技術人員可由本說明書所公開的內容瞭解本發明的優點與效果。本發明可通過其他不同的具體實施例加以施行或應用,本說明書中的各項細節也可基於不同觀點與應用,在不背離本發明的構思下進行各種修改與變更。另外,本發明的附圖僅為簡單示意說明,並非依實際尺寸的描繪,事先聲明。以下的實施方式將進一步詳細說明本發明的相關技術內容,但所公開的內容並非用以限制本發明的保護範圍。另外,本文中所使用的術語“或”,應視實際情況可能包括相關聯的列出項目中的任一個或者多個的組合。The implementation of the "device for controlling a Raman spectrometer" disclosed in the present invention is described below through specific specific examples. Those skilled in the art can understand the advantages and effects of the present invention from the content disclosed in this specification. The present invention can be implemented or applied through other different specific embodiments, and various modifications and changes can be made to the details in this specification based on different viewpoints and applications without departing from the concept of the present invention. In addition, the drawings of the present invention are only for simple illustration, and are not drawn according to the actual size, which is stated in advance. The following embodiments will further describe the relevant technical content of the present invention in detail, but the disclosed content is not intended to limit the protection scope of the present invention. In addition, the term "or" used herein may include any one or a combination of more of the associated listed items depending on the actual situation.

[第一實施例][first embodiment]

參閱圖1所示,本發明第一實施例提供一種用於控制拉曼光譜儀的裝置D,用於控制拉曼光譜儀的裝置D可以設置於一拉曼光譜儀內或外接於拉曼光譜儀,其包括:一影像擷取分析單元1、一處理單元2、一人機介面單元3以及一載物控制單元4。Referring to Fig. 1, the first embodiment of the present invention provides a device D for controlling a Raman spectrometer, the device D for controlling a Raman spectrometer can be arranged in a Raman spectrometer or externally connected to a Raman spectrometer, which includes : an image capturing and analyzing unit 1 , a processing unit 2 , a man-machine interface unit 3 and a loading control unit 4 .

影像擷取分析單元1用以拍攝一待測物M,以獲得待測物M的影像資訊IMG。影像擷取分析單元1可以包括光學感測元件,例如但不限於電荷耦合裝置(charge coupled device,CCD)或互補式金屬氧化物半導體(complementary metal-oxide semiconductor,CMOS)影像感應器。在一實施例中,影像擷取分析單元1連接一光學鏡頭,光學鏡頭擷取待測物M的影像,影像擷取分析單元1則可分析待測物M的影像以獲得一影像資訊IMG,並將影像資訊IMG分為多個區塊,且每一區塊具有其對應的區塊資訊。舉例來說,影像資訊IMG可以是待測物M的光學特徵,例如外型輪廓、亮度、色彩等,但本發明不予限制。更進一步,區塊資訊可以是區塊的光學特徵,例如亮度、色彩、灰階值、色塊密度、色塊面積等,但本發明不予限制。The image capturing and analyzing unit 1 is used for photographing an object M to obtain image information IMG of the object M. The image capturing and analyzing unit 1 may include an optical sensing element, such as but not limited to a charge coupled device (CCD) or a complementary metal-oxide semiconductor (CMOS) image sensor. In one embodiment, the image capturing and analyzing unit 1 is connected with an optical lens, and the optical lens captures an image of the object M to be measured, and the image capturing and analyzing unit 1 can analyze the image of the object M to obtain image information IMG. And the image information IMG is divided into multiple blocks, and each block has its corresponding block information. For example, the image information IMG may be the optical characteristics of the object under test M, such as outline, brightness, color, etc., but the present invention is not limited thereto. Furthermore, the block information may be the optical characteristics of the block, such as brightness, color, gray scale value, color block density, color block area, etc., but the present invention is not limited thereto.

處理單元2電性連接影像擷取分析單元1。處理單元2可以將影像資訊IMG的多個區塊分別與一預定影像資訊數值範圍比對以決定每一區塊的第一優先分析等級。舉例來說,預定影像資訊數值範圍可以是一預定亮度數值範圍,而預定亮度數值範圍為影像灰階值介於120至250,當多個區塊的其中之一區塊的區塊資訊數值落在預定亮度數值範圍時,即區塊影像灰階值介於120至250時,處理單元2將多個區塊的其中之一區塊紀錄為具有第一優先分析等級。當多個區塊的另外之一區塊的區塊資訊數值未落在預定亮度數值範圍時,即區塊影像灰階值小於120或大於250時,處理單元2將多個區塊的另外之一區塊紀錄為不具有第一優先分析等級。須說明的是,在本實施例中,雖然以數值範圍作為比對的基礎,但在其他實施例中亦可以一門檻值作為比對的基礎,本發明不以此為限。The processing unit 2 is electrically connected to the image capturing and analyzing unit 1 . The processing unit 2 can compare the multiple blocks of the image information IMG with a predetermined value range of the image information to determine the first priority analysis level of each block. For example, the predetermined image information value range may be a predetermined brightness value range, and the predetermined brightness value range is an image grayscale value between 120 and 250, when the block information value of one of the multiple blocks falls When the brightness value range is predetermined, that is, when the grayscale value of the block image is between 120 and 250, the processing unit 2 records one of the blocks as having the first priority analysis level. When the block information value of another block of the multiple blocks does not fall within the predetermined brightness value range, that is, when the gray scale value of the block image is less than 120 or greater than 250, the processing unit 2 converts the other block of the multiple blocks to A block record does not have the first priority analysis level. It should be noted that, in this embodiment, although the numerical range is used as the basis for comparison, in other embodiments, a threshold value may also be used as the basis for comparison, and the present invention is not limited thereto.

此外,用於控制拉曼光譜儀的裝置D還可以包括一資料庫(未示於圖中),資料庫可以電性連接或是通訊連接處理單元2及人機介面單元3。資料庫可存儲不同種類生物或非生物的影像資訊或拉曼光譜型態,可用以與待測物M比較分析以預測或決定待測物M的分類。In addition, the device D for controlling the Raman spectrometer may also include a database (not shown in the figure), and the database may be electrically or communicatively connected to the processing unit 2 and the man-machine interface unit 3 . The database can store image information or Raman spectrum patterns of different types of organisms or non-organisms, which can be used for comparison and analysis with the analyte M to predict or determine the classification of the analyte M.

人機介面單元3電性連接影像擷取分析單元1及處理單元2。如圖2所示,人機介面單元3可包括一使用者介面,使用者介面可用以儲存並顯示關於影像資訊IMG或區塊資訊的使用者介面配置數據,且使用者介面可以是具有液晶顯示器(Liquid-crystal display,LCD)或有機發光二極體(Organic light-emitting diode,OLED)顯示器等的裝置,本發明不以此為限。舉例來說,如圖2所示,使用者介面可以配置有一顯示模組31,顯示模組31可通過顯示器的畫面顯示待測物M的一即時影像或一非即時影像,以提供給一使用者參考。此外,人機介面單元3可以通過鍵盤、滑鼠、觸控板或觸控螢幕的輸入裝置接收來自使用者的使用者輸入,本發明不以此為限。使用者介面還可以配置人機介面控制模組32,通過人機介面控制模組32,待測物M的檢測過程中的不同階段可被控制,舉例來說,檢測過程中的不同階段可包括檢測開始功能、檢測結束功能、顯示模組31顯示待測物M的影像控制功能等,而人機介面控制模組32的配置可根據使用者需求進行調整,本發明不以此為限。此外,人機介面控制模組32還可配置一使用者手動控制單元,以便於檢測過程中控制承載待測物M的載台移動(包括移入/移出拉曼光譜儀等)功能、雷射參數(包括雷射能量、時間、收發次數等)功能、雷射偵測器溫度功能、及量測模式(包括快速、精確、高精確模式等)功能等。使用者手動控制單元的配置可根據使用者需求進行調整,本發明不以此為限。The man-machine interface unit 3 is electrically connected to the image capture analysis unit 1 and the processing unit 2 . As shown in Figure 2, the man-machine interface unit 3 can include a user interface, which can be used to store and display user interface configuration data about image information IMG or block information, and the user interface can have a liquid crystal display (Liquid-crystal display, LCD) or organic light-emitting diode (Organic light-emitting diode, OLED) display and other devices, the present invention is not limited thereto. For example, as shown in FIG. 2, the user interface can be configured with a display module 31, and the display module 31 can display a real-time image or a non-real-time image of the object under test M through the screen of the display, so as to provide a user reference. In addition, the man-machine interface unit 3 can receive user input from the user through an input device such as a keyboard, a mouse, a touch panel or a touch screen, and the present invention is not limited thereto. The user interface can also be configured with a man-machine interface control module 32. Through the man-machine interface control module 32, different stages in the detection process of the object under test M can be controlled. For example, different stages in the detection process can include The detection start function, the detection end function, the image control function of the display module 31 displaying the object under test M, etc., and the configuration of the man-machine interface control module 32 can be adjusted according to user needs, and the present invention is not limited thereto. In addition, the man-machine interface control module 32 can also be equipped with a user manual control unit, so as to control the movement of the stage carrying the object M to be tested (including moving in/out of the Raman spectrometer, etc.) function, laser parameters ( Including laser energy, time, times of sending and receiving, etc.), laser detector temperature function, and measurement mode (including fast, accurate, high-precision mode, etc.) functions, etc. The configuration of the user's manual control unit can be adjusted according to the needs of the user, and the present invention is not limited thereto.

此外,使用者介面還可以配置一待測物配置模組33,用以顯示待測物M的一配置模式,並可提供待測物M的快速定位功能。使用者介面可以再配置一拉曼光譜圖形模組34,拉曼光譜圖形模組34可顯示待測物M的一即時拉曼光譜圖形影像或一非即時拉曼光譜圖形影像。使用者介面可以再配置一拉曼光譜預測結果顯示模組35,拉曼光譜預測結果顯示模組35可顯示待測物M的拉曼光譜預測結果,以提供給使用者決定是否進行後續拉曼光譜結果分析。In addition, the user interface can also be configured with a DUT configuration module 33 for displaying a configuration mode of the DUT M and providing a quick positioning function of the UUT M. The user interface can further be configured with a Raman spectrum graphics module 34, and the Raman spectrum graphics module 34 can display a real-time Raman spectrum graphics image or a non-real-time Raman spectrum graphics image of the object M to be measured. The user interface can be configured with a Raman spectrum prediction result display module 35. The Raman spectrum prediction result display module 35 can display the Raman spectrum prediction result of the object M to provide for the user to decide whether to perform subsequent Raman. Analysis of spectral results.

進一步而言,人機介面單元3可以包括一第一全自動模式模組,第一全自動模式模組包括一第一全自動模式。詳細來說,如圖3所示,在第一全自動模式下,人機介面單元3的第一全自動模式模組根據處理單元2分析結果自動決定與記錄每一區塊是否具有第一優先分析等級,接著自動記錄具有一第二優先分析等級的取樣區域,並傳送一第一全自動控制訊號ACS1至載物控制單元4以通過載物控制單元4控制取樣區域進行位移,及根據包括取樣區域的影像資訊IMG或區塊資訊進行拉曼光譜分析。也就是說,在第一全自動模式下,人機介面單元3可自動完成所有拉曼光譜檢測過程。需說明的是,此處的第一優先分析等級之判斷例如是根據分析影像資訊IMG或區塊資訊來識別該區塊中是否存在或具有足夠的樣本數量;而第二優先分析等級之判斷例如是根據分析影像資訊IMG或區塊資訊來識別該區塊中的樣本密度。然而,本發明不以此為限,判斷具有第一優先分析等級或第二優先分析等級的依據可以依照使用者的需求改變。Further, the man-machine interface unit 3 may include a first fully automatic mode module, and the first fully automatic mode module includes a first fully automatic mode. In detail, as shown in FIG. 3, in the first fully automatic mode, the first fully automatic mode module of the man-machine interface unit 3 automatically determines and records whether each block has the first priority according to the analysis result of the processing unit 2. Analysis level, then automatically record the sampling area with a second priority analysis level, and send a first fully automatic control signal ACS1 to the loading control unit 4 to control the displacement of the sampling area through the loading control unit 4, and according to the included sampling The image information IMG or block information of the region is analyzed by Raman spectroscopy. That is to say, in the first fully automatic mode, the man-machine interface unit 3 can automatically complete all Raman spectrum detection processes. It should be noted that the judgment of the first priority analysis level here is, for example, based on the analysis of image information IMG or block information to identify whether the block exists or has a sufficient number of samples; and the judgment of the second priority analysis level is, for example, The sample density in the block is identified according to the analyzed image information IMG or the block information. However, the present invention is not limited thereto, and the basis for judging whether to have the first priority analysis level or the second priority analysis level can be changed according to the needs of users.

更進一步地,人機介面單元3還可包括一第一模式模組與一第二模式模組。第一模式模組包括一第一模式,且第一模式為一半自動量測模式。第二模式模組包括一第二模式,且第二模式為一使用者手動量測模式。Furthermore, the man-machine interface unit 3 may further include a first mode module and a second mode module. The first mode module includes a first mode, and the first mode is a semi-automatic measurement mode. The second mode module includes a second mode, and the second mode is a user manual measurement mode.

如圖4所示,在第一模式下,人機介面單元3的第一模式模組根據處理單元2的分析結果,自動決定與記錄每一區塊是否具有第一優先分析等級,並提供一第一指示給使用者。之後,針對一對應第一指示的使用者輸入,人機介面單元3的第一模式模組對應地自動記錄具有一第二優先分析等級的取樣區域,並傳送一第一控制訊號CS1至載物控制單元4以通過載物控制單元4控制取樣區域進行位移,並根據取樣區域的影像資訊IMG或區塊資訊進行拉曼光譜分析。As shown in Figure 4, in the first mode, the first mode module of the man-machine interface unit 3 automatically determines and records whether each block has the first priority analysis level according to the analysis result of the processing unit 2, and provides a The first instruction is to the user. Afterwards, in response to a user input corresponding to the first instruction, the first mode module of the man-machine interface unit 3 correspondingly automatically records the sampling area with a second priority analysis level, and sends a first control signal CS1 to the load The control unit 4 controls the displacement of the sampling area through the loading control unit 4, and performs Raman spectrum analysis according to the image information IMG or block information of the sampling area.

如圖5所示,在第二模式下,人機介面單元3根據使用者輸入決定取樣區域。在一實施例中,人機介面單元3接收一使用者輸入(對應使用者欲選擇一取樣區域)後,人機介面單元3的第二模式模組根據取樣區域的影像資訊IMG或區塊資訊是否具有第一優先分析等級來提供一第二指示給使用者。之後,針對一對應第二指示的使用者指示,人機介面單元3的第二模式模組對應地決定是否紀錄取樣區域具有第二優先分析等級,並根據取樣區域是否具有第二優先分析等級傳送一第二控制訊號CS2至載物控制單元4,以通過載物控制單元4控制待測物M的位置,使具有第二優先分析等級的取樣區域進行位移,並根據包括取樣區域的影像資訊IMG或區塊資訊進行拉曼光譜分析。在一實施例中,人機介面單元3的第二模式模組提供的第二指示是根據區域範圍的影像資訊IMG或區塊資訊具有第一優先分析等級,因此第二指示的內容可以為「建議使用者決定紀錄取樣區域具有第二優先分析等級」。在另一實施例中,人機介面單元3的第二模式模組提供的第二指示是「根據區域範圍的影像資訊IMG或區塊資訊不具有第一優先分析等級」,因此第二指示的內容可以為「建議使用者不要紀錄取樣區域具有第二優先分析等級」。然而,使用者也可以不依照第二指示的內容,並依其需要決定是否輸入對應第二指示的使用者指示,使用者也可以重新選取取樣區域,並再次執行第二模式的運作。此外,第二指示可以根據實際需求進行調整,本發明不以此為限。As shown in FIG. 5 , in the second mode, the man-machine interface unit 3 determines the sampling area according to user input. In one embodiment, after the human-machine interface unit 3 receives a user input (corresponding to the user's desire to select a sampling area), the second mode module of the human-machine interface unit 3 according to the image information IMG or block information of the sampling area Whether there is a first priority analysis level to provide a second indication to the user. Afterwards, for a user instruction corresponding to the second instruction, the second mode module of the man-machine interface unit 3 correspondingly determines whether the record sampling area has the second priority analysis level, and transmits according to whether the sampling area has the second priority analysis level. A second control signal CS2 is sent to the loading control unit 4, so as to control the position of the object M to be tested through the loading control unit 4, so that the sampling area with the second priority analysis level is displaced, and according to the image information IMG including the sampling area or block information for Raman spectroscopy analysis. In one embodiment, the second instruction provided by the second mode module of the man-machine interface unit 3 is based on the image information IMG or block information of the area range having the first priority analysis level, so the content of the second instruction can be " It is recommended that users decide to record the sampling area as having a second priority level of analysis." In another embodiment, the second instruction provided by the second mode module of the man-machine interface unit 3 is "the image information IMG or block information according to the area range does not have the first priority analysis level", so the second instruction The content can be "recommend users not to record that the sampling area has the second priority analysis level". However, the user can also decide whether to input the user instruction corresponding to the second instruction according to his need, not according to the content of the second instruction. The user can also reselect the sampling area and execute the operation of the second mode again. In addition, the second indication may be adjusted according to actual needs, and the present invention is not limited thereto.

載物控制單元4電性連接人機介面單元3。在第一模式下,人機介面單元3的第一模式模組根據對應第一指示的使用者輸入,自動記錄具有第二優先分析等級的取樣區域,並傳送第一控制訊號CS1至載物控制單元4。或者,在第二模式下,人機介面單元3的第二模式模組根據對應第二指示的使用者輸入,記錄具有第二優先分析等級的取樣區域,並傳送第二控制訊號CS2至載物控制單元4。藉此,通過載物控制單元4控制移動待測物M,以使具有第二優先分析等級的取樣區域進行拉曼光譜檢測。載物控制單元4連接設置於拉曼光譜儀內的一載台,載台由一步進馬達或一伺服馬達驅動。在一較佳實施例中,載物控制單元4連接伺服馬達驅動的載台。此外,載物控制單元4連接的載台可以為一單軸載台或一多軸載台。在一較佳實施例中,載物控制單元4連接的載台為多軸載台。在一更佳實施例中,載物控制單元4連接的載台為一三軸載台。更進一步,載台大小及形狀可以根據實際需求進行調整,且載台上承載待測物M之區域的面積、形狀亦可以根據實際需求進行調整,本發明不予限制。The load control unit 4 is electrically connected to the man-machine interface unit 3 . In the first mode, the first mode module of the man-machine interface unit 3 automatically records the sampling area with the second priority analysis level according to the user input corresponding to the first instruction, and sends the first control signal CS1 to the loading control Unit 4. Or, in the second mode, the second mode module of the human-machine interface unit 3 records the sampling area with the second priority analysis level according to the user input corresponding to the second instruction, and sends the second control signal CS2 to the load control unit4. In this way, the object M to be moved is controlled by the object control unit 4, so that the sampling area with the second priority analysis level can be detected by Raman spectroscopy. The object control unit 4 is connected to a stage set in the Raman spectrometer, and the stage is driven by a stepping motor or a servo motor. In a preferred embodiment, the load control unit 4 is connected to a stage driven by a servo motor. In addition, the stage connected to the object control unit 4 can be a single-axis stage or a multi-axis stage. In a preferred embodiment, the stage connected to the object control unit 4 is a multi-axis stage. In a more preferred embodiment, the stage connected to the object control unit 4 is a three-axis stage. Furthermore, the size and shape of the stage can be adjusted according to actual needs, and the area and shape of the area carrying the object M to be measured on the stage can also be adjusted according to actual needs, which is not limited by the present invention.

然而,上述所舉的例子只是其中一可行的實施例而並非用以限定本發明。However, the above-mentioned example is only one possible embodiment and is not intended to limit the present invention.

[第二實施例][Second embodiment]

第二實施例與第一實施例的差別在於雷射量測控制單元,也就是說,本發明的用於控制拉曼光譜儀的裝置可以具有一雷射量測控制單元。另外,須說明的是,第二實施例所提供的用於控制拉曼光譜儀的裝置D的其他結構與前述第一實施例相仿,在此不再贅述。The difference between the second embodiment and the first embodiment lies in the laser measurement control unit, that is to say, the device for controlling a Raman spectrometer of the present invention may have a laser measurement control unit. In addition, it should be noted that other structures of the device D for controlling a Raman spectrometer provided by the second embodiment are similar to those of the first embodiment, and will not be repeated here.

參閱圖6所示,在本實施例中,本發明提供的用於控制拉曼光譜儀的裝置D還可以包括一雷射量測控制單元5。雷射量測控制單元5電性連接人機介面單元3及載物控制單元4。雷射量測控制單元5對應第一指示或第二指示的使用者輸入,對於被記錄具有第二優先分析等級的取樣區域的影像資訊IMG或區塊資訊分析,並決定取樣區域的雷射量測相關參數。Referring to FIG. 6 , in this embodiment, the device D for controlling a Raman spectrometer provided by the present invention may further include a laser measurement control unit 5 . The laser measurement control unit 5 is electrically connected to the man-machine interface unit 3 and the load control unit 4 . The laser measurement control unit 5 responds to the user input of the first instruction or the second instruction, analyzes the image information IMG or block information of the sampling area recorded with the second priority analysis level, and determines the laser dose of the sampling area Measure the relevant parameters.

類似於第一實施例所述,在本實施例中,人機介面單元3也可包括一第二全自動模式模組,且第二全自動模式模組包括一第二全自動模式。詳細來說,如圖7所示,在第二全自動模式下,人機介面單元3的第二全自動模式模組根據處理單元2分析結果自動決定與記錄每一區塊是否具有第一優先分析等級,接著自動記錄具有一第二優先分析等級的取樣區域並傳送至雷射量測控制單元5。雷射量測控制單元5根據具有第二優先分析等級的取樣區域的影像資訊IMG或區塊資訊進行分析,並自動決定是否紀錄取樣區域具有第三優先分析等級,並傳送一第二全自動控制訊號ACS2至載物控制單元4以通過載物控制單元4控制取樣區域進行位移,及根據包括取樣區域的影像資訊IMG或區塊資訊進行拉曼光譜分析。也就是說,在第二全自動模式下,人機介面單元3及雷射量測控制單元5可自動完成所有拉曼光譜檢測過程。需說明的是,此處的第一優先分析等級之判斷例如是根據分析影像資訊IMG或區塊資訊來識別該區塊中是否存在或具有足夠的樣本數量;而第二優先分析等級之判斷例如是根據分析影像資訊IMG或區塊資訊來識別該區塊中的樣本密度;第三優先分析等級之判斷例如是根據分析影像資訊IMG或區塊資訊來識別該區塊中的色彩、灰階分布等。然而,本發明不以此為限,判斷具有第一優先分析等級、第二優先分析等級、第三優先分析等級的依據可以依照使用者的需求改變。Similar to the first embodiment, in this embodiment, the man-machine interface unit 3 may also include a second fully automatic mode module, and the second fully automatic mode module includes a second fully automatic mode. In detail, as shown in FIG. 7, in the second fully automatic mode, the second fully automatic mode module of the man-machine interface unit 3 automatically determines and records whether each block has the first priority according to the analysis result of the processing unit 2. The analysis level, and then automatically record the sampling area with a second priority analysis level and send it to the laser measurement control unit 5 . The laser measurement control unit 5 analyzes the image information IMG or block information of the sampling area with the second priority analysis level, and automatically determines whether to record the sampling area with the third priority analysis level, and sends a second automatic control The signal ACS2 is sent to the object control unit 4 to control the displacement of the sampling area through the object control unit 4, and perform Raman spectrum analysis according to the image information IMG or block information including the sampling area. That is to say, in the second fully automatic mode, the man-machine interface unit 3 and the laser measurement control unit 5 can automatically complete all the Raman spectrum detection processes. It should be noted that the judgment of the first priority analysis level here is, for example, to identify whether the block exists or has a sufficient number of samples according to the analysis of image information IMG or block information; and the judgment of the second priority analysis level is, for example, The sample density in the block is identified based on the analysis of image information IMG or block information; the judgment of the third priority analysis level is, for example, based on the analysis of image information IMG or block information to identify the color and grayscale distribution in the block wait. However, the present invention is not limited thereto, and the basis for judging whether there is a first priority analysis level, a second priority analysis level, or a third priority analysis level can be changed according to user requirements.

在本實施例中,人機介面單元3還可包括一第三模式模組及一第四模式模組。第三模式模組包括一第三模式,第三模式為一半自動量測模式,且第三模式中的前半段程序已隱含了第一模式,或是說第三模式中的後半段程序可與第一模式串聯運作。第四模式模組包括一第四模式,且第四模式為一使用者手動量測模式。In this embodiment, the man-machine interface unit 3 may further include a third mode module and a fourth mode module. The third mode module includes a third mode, the third mode is a semi-automatic measurement mode, and the first half of the program in the third mode has implied the first mode, or the second half of the program in the third mode can be Operates in tandem with the first mode. The fourth mode module includes a fourth mode, and the fourth mode is a user manual measurement mode.

如圖8所示,在第三模式下,人機介面單元3的第三模式模組根據處理單元2的分析結果自動決定與記錄每一區塊是否具有第一優先分析等級,並提供第三指示給使用者,針對對應第三指示的使用者輸入,人機介面單元3的第三模式模組自動記錄具有第二優先分析等級的取樣區域並傳送至人機介面單元3的第三模式模組。人機介面單元3的第三模式模組再將記錄具有第二優先分析等級的取樣區域的影像資訊IMG或區塊資訊傳送至雷射量測控制單元5。雷射量測控制單元5根據具有第二優先分析等級的取樣區域的影像資訊IMG或區塊資訊進行分析,並決定取樣區域是否具有第三優先分析等級。接著,雷射量測控制單元5傳送一第三指示訊號至人機介面單元3的第三模式模組。人機介面單元3的第三模式模組自動記錄具有第三優先分析等級的取樣區域,並傳送一第三控制訊號CS3至載物控制單元4以通過載物控制單元4控制具有第三優先分析等及的取樣區域進行位移,及根據包括取樣區域的影像資訊IMG或區塊資訊進行拉曼光譜分析。As shown in Figure 8, in the third mode, the third mode module of the man-machine interface unit 3 automatically determines and records whether each block has the first priority analysis level according to the analysis result of the processing unit 2, and provides the third Indicate to the user, for the user input corresponding to the third instruction, the third mode module of the man-machine interface unit 3 automatically records the sampling area with the second priority analysis level and sends it to the third mode module of the man-machine interface unit 3 Group. The third mode module of the man-machine interface unit 3 then sends the image information IMG or block information recording the sampling area with the second priority analysis level to the laser measurement control unit 5 . The laser measurement control unit 5 analyzes according to the image information IMG or block information of the sampling area with the second priority analysis level, and determines whether the sampling area has the third priority analysis level. Next, the laser measurement control unit 5 sends a third instruction signal to the third mode module of the man-machine interface unit 3 . The third mode module of the man-machine interface unit 3 automatically records the sampling area with the third priority analysis level, and sends a third control signal CS3 to the loading control unit 4 to control the analysis with the third priority through the loading control unit 4 The equal sampling area is shifted, and the Raman spectrum analysis is performed according to the image information IMG or block information including the sampling area.

如圖9所示,在第四模式下,人機介面單元3的第四模式模組接收使用者的一使用者輸入(對應使用者欲選擇一取樣區域)決定紀錄取樣區域具有第二優先分析等級,雷射量測控制單元5根據具有第二優先分析等級的取樣區域的影像資訊IMG或區塊資訊進行分析,並決定取樣區域是否具有第三優先分析等級。接著,雷射量測控制單元5傳送一第四指示訊號至人機介面單元3的第四模式模組,人機介面單元3的第四模式模組提供一第四指示給使用者。之後,針對一對應第四指示的使用者輸入,人機介面單元3的第四模式模組對應地決定是否紀錄取樣區域具有第三優先分析等級,並根據取樣區域是否具有第三優先分析等級傳送一第四控制訊號CS4至載物控制單元4,以通過載物控制單元4控制待測物M的位置,使具有第三優先分析等級的取樣區域進行位移,並根據包括取樣區域的影像資訊IMG或區塊資訊進行拉曼光譜分析。在一實施例中,人機介面單元3的第四模式模組提供的第四指示是「根據區域範圍的影像資訊IMG或區塊資訊具有第三優先分析等級」,因此第四指示的內容可以為「建議使用者決定紀錄取樣區域具有第三優先分析等級」。在另一實施例中,人機介面單元3的第四模式模組提供的第四指示是「根據區域範圍的影像資訊IMG或區塊資訊不具有第三優先分析等級」,因此第四指示的內容可以為「建議使用者不要紀錄取樣區域具有第三優先分析等級」。然而,使用者也可以不依照第四指示的內容,並依其需要決定是否輸入對應第四指示的使用者指示,使用者也可以重新選取取樣區域,並再次執行第四模式的運作。此外,第四指示可以跟據實際需求進行調整,本發明不以此為限。As shown in Figure 9, in the fourth mode, the fourth mode module of the human-machine interface unit 3 receives a user input from the user (corresponding to the user's desire to select a sampling area) and determines that the recording sampling area has the second priority analysis level, the laser measurement control unit 5 analyzes the image information IMG or block information of the sampling area with the second priority analysis level, and determines whether the sampling area has the third priority analysis level. Next, the laser measurement control unit 5 sends a fourth indication signal to the fourth mode module of the man-machine interface unit 3, and the fourth mode module of the man-machine interface unit 3 provides a fourth indication to the user. Afterwards, for a user input corresponding to the fourth instruction, the fourth mode module of the man-machine interface unit 3 correspondingly determines whether the record sampling area has the third priority analysis level, and transmits according to whether the sampling area has the third priority analysis level. A fourth control signal CS4 is sent to the loading control unit 4 to control the position of the object M to be tested through the loading control unit 4, so that the sampling area with the third priority analysis level is displaced, and according to the image information IMG including the sampling area or block information for Raman spectroscopy analysis. In one embodiment, the fourth instruction provided by the fourth mode module of the man-machine interface unit 3 is "the image information IMG or block information of the area range has the third priority analysis level", so the content of the fourth instruction can be It is "recommended that the user decides to record the sampling area with the third priority level of analysis". In another embodiment, the fourth instruction provided by the fourth mode module of the man-machine interface unit 3 is "the image information IMG or block information according to the area range does not have the third priority analysis level", so the fourth instruction The content can be "recommend users not to record that the sampling area has the third priority analysis level". However, the user may not follow the content of the fourth instruction, but may decide whether to input the user instruction corresponding to the fourth instruction according to his needs. The user may also re-select the sampling area and execute the operation of the fourth mode again. In addition, the fourth indication can be adjusted according to actual needs, and the present invention is not limited thereto.

然而,上述所舉的例子只是其中一可行的實施例而並非用以限定本發明。However, the above-mentioned example is only one possible embodiment and is not intended to limit the present invention.

[第三實施例][Third embodiment]

第三實施例與第一實施例或第二實施例的差別在於清潔控制單元,也就是說,本發明的用於控制拉曼光譜儀的裝置可以具有一清潔控制單元。另外,須說明的是,第三實施例所提供的用於控制拉曼光譜儀的裝置D的其他結構與前述第一實施例或第二實施例相仿,在此不再贅述。The difference between the third embodiment and the first embodiment or the second embodiment lies in the cleaning control unit, that is to say, the device for controlling a Raman spectrometer of the present invention may have a cleaning control unit. In addition, it should be noted that other structures of the device D for controlling a Raman spectrometer provided by the third embodiment are similar to those of the first embodiment or the second embodiment, and will not be repeated here.

參閱圖10所示,在本實施例中,本發明提供的用於控制拉曼光譜儀的裝置D還可以包括一清潔控制單元6。清潔控制單元6電性連接人機介面單元3。Referring to FIG. 10 , in this embodiment, the device D for controlling a Raman spectrometer provided by the present invention may further include a cleaning control unit 6 . The cleaning control unit 6 is electrically connected to the man-machine interface unit 3 .

在一實施例中,清潔控制單元6可以在每次拉曼光譜儀啟動後自動傳送一清潔控制訊號CCS至設置於拉曼光譜儀內的一清潔單元,以使清潔單元對拉曼光譜儀內一檢測空間進行清潔。清潔單元可以包括一紫外線模組,本發明不以此為限。In one embodiment, the cleaning control unit 6 can automatically send a cleaning control signal CCS to a cleaning unit provided in the Raman spectrometer after each Raman spectrometer is started, so that the cleaning unit can control a detection space in the Raman spectrometer Clean up. The cleaning unit may include an ultraviolet module, but the invention is not limited thereto.

在一實施例中,人機介面單元3還可以包括一第五模式模組,且第五模式模組包括一第五模式。如圖11所示,在第五模式中,載台每次退離拉曼光譜儀的檢測空間後,清潔控制單元6可根據承載待測物M的一基板的使用次數、載台進出拉曼光譜儀的檢測空間的次數、或拉曼光譜儀持續啟動狀態的時間傳送一第五指示訊號至人機介面單元3的第五模式模組,人機介面單元3的第五模式模組根據第五指示訊號提供一第五指示。針對一對應第五指示的使用者輸入,人機介面單元3的第五模式模組決定是否傳送一第五控制訊號CS5至清潔控制單元6,以使清潔控制單元6傳送清潔控制訊號CCS至拉曼光譜儀內的清潔單元,以清潔拉曼光譜儀內的檢測空間。In an embodiment, the man-machine interface unit 3 may further include a fifth mode module, and the fifth mode module includes a fifth mode. As shown in FIG. 11 , in the fifth mode, after the stage leaves the detection space of the Raman spectrometer each time, the cleaning control unit 6 can enter and exit the Raman spectrometer according to the number of times of use of a substrate carrying the object M to be measured. The number of times of the detection space, or the time that the Raman spectrometer is continuously activated, sends a fifth indication signal to the fifth mode module of the man-machine interface unit 3, and the fifth mode module of the man-machine interface unit 3 according to the fifth indication signal A fifth instruction is provided. For a user input corresponding to the fifth instruction, the fifth mode module of the man-machine interface unit 3 determines whether to send a fifth control signal CS5 to the cleaning control unit 6, so that the cleaning control unit 6 sends the cleaning control signal CCS to the pull The cleaning unit in the Raman spectrometer to clean the detection space in the Raman spectrometer.

然而,上述所舉的例子只是其中一可行的實施例而並非用以限定本發明。However, the above-mentioned example is only one possible embodiment and is not intended to limit the present invention.

此外,上述的第一模式模組、第二模式模組、第三模式模組、第四模式模組及第五模式模組可以是軟體、韌體、硬體或其他可以達成上述功能之軟體、韌體、硬體之組合。In addition, the above-mentioned first mode module, second mode module, third mode module, fourth mode module and fifth mode module can be software, firmware, hardware or other software that can achieve the above functions , firmware, and hardware combination.

[實施例的有益效果][Advantageous Effects of Embodiment]

本發明的其中一有益效果在於,本發明所提供的用於控制拉曼光譜儀的裝置,其能通過“影像擷取分析單元用於獲取一待測物的一影像資訊,並將影像資訊分為多個區塊,每一區塊具有對應的一區塊資訊,處理單元將其中一區塊資訊與一預定影像資訊數值範圍或門檻值比對以決定對應的區塊是否具有第一優先分析等級,人機介面單元針對具有第一優先分析等級的各個區塊分別接收一使用者輸入,以記錄各個區塊是否具有第二優先分析等級”的技術方案,以加強使用者與拉曼光譜儀之間的人機互動,並提升拉曼光譜儀的控制,減少量測時間及優化檢測結果。One of the beneficial effects of the present invention is that the device for controlling the Raman spectrometer provided by the present invention can be used to obtain an image information of an object under test through the "image capture and analysis unit, and divide the image information into A plurality of blocks, each block has a corresponding piece of block information, and the processing unit compares one of the block information with a predetermined image information value range or threshold value to determine whether the corresponding block has the first priority analysis level , the human-machine interface unit receives a user input for each block with the first priority analysis level, to record whether each block has the second priority analysis level "technical solution to strengthen the relationship between the user and the Raman spectrometer Human-computer interaction, and improve the control of Raman spectrometers, reduce measurement time and optimize detection results.

以上所公開的內容僅為本發明的優選可行實施例,並非因此侷限本發明的申請專利範圍,所以凡是運用本發明說明書及圖式內容所做的等效技術變化,均包含於本發明的申請專利範圍內。The content disclosed above is only a preferred feasible embodiment of the present invention, and does not therefore limit the scope of the patent application of the present invention. Therefore, all equivalent technical changes made by using the description and drawings of the present invention are included in the application of the present invention. within the scope of the patent.

D:用於控制拉曼光譜儀的裝置 1:影像擷取分析單元 2:處理單元 3:人機介面單元 31:顯示模組 32:人機介面控制模組 33:待測物配置模組 34:拉曼光譜圖形模組 35:拉曼光譜預測結果顯示模組 4:載物控制單元 5:雷射量測控制單元 6:清潔控制單元 D: The device used to control the Raman spectrometer 1: Image capture and analysis unit 2: Processing unit 3: Human-machine interface unit 31: Display module 32: Man-machine interface control module 33: DUT configuration module 34: Raman spectrum graphics module 35: Raman spectrum prediction result display module 4:Load control unit 5: Laser measurement control unit 6: Clean the control unit

圖1為本發明第一實施例的用於控制拉曼光譜儀的裝置的功能方塊圖。FIG. 1 is a functional block diagram of a device for controlling a Raman spectrometer according to a first embodiment of the present invention.

圖2為本發明第一實施例的用於控制拉曼光譜儀的裝置的使用者介面示意圖。FIG. 2 is a schematic diagram of a user interface of the device for controlling a Raman spectrometer according to the first embodiment of the present invention.

圖3為本發明第一實施例的用於控制拉曼光譜儀的裝置的第一全自動模式模組的第一全自動模式流程圖。3 is a flow chart of the first full-automatic mode of the first full-automatic mode module of the device for controlling a Raman spectrometer according to the first embodiment of the present invention.

圖4為本發明第一實施例的用於控制拉曼光譜儀的裝置的第一模式模組的第一模式流程圖。FIG. 4 is a flow chart of the first mode of the first mode module of the device for controlling a Raman spectrometer according to the first embodiment of the present invention.

圖5為本發明第一實施例的用於控制拉曼光譜儀的裝置的第二模式模組的第二模式流程圖。5 is a flow chart of the second mode of the second mode module of the device for controlling a Raman spectrometer according to the first embodiment of the present invention.

圖6為本發明第二實施例的用於控制拉曼光譜儀的裝置的功能方塊圖。FIG. 6 is a functional block diagram of an apparatus for controlling a Raman spectrometer according to a second embodiment of the present invention.

圖7為本發明第二實施例的用於控制拉曼光譜儀的裝置的第二全自動模式模組的第二全自動模式流程圖。FIG. 7 is a flow chart of the second full-automatic mode of the second full-automatic mode module of the device for controlling a Raman spectrometer according to the second embodiment of the present invention.

圖8為本發明第二實施例的用於控制拉曼光譜儀的裝置的第三模式模組的第三模式流程圖。FIG. 8 is a flow chart of the third mode of the third mode module of the device for controlling a Raman spectrometer according to the second embodiment of the present invention.

圖9為本發明第二實施例的用於控制拉曼光譜儀的裝置的第四模式模組的第四模式流程圖。FIG. 9 is a flow chart of the fourth mode of the fourth mode module of the device for controlling a Raman spectrometer according to the second embodiment of the present invention.

圖10為本發明第三實施例的用於控制拉曼光譜儀的裝置的功能方塊圖。FIG. 10 is a functional block diagram of an apparatus for controlling a Raman spectrometer according to a third embodiment of the present invention.

圖11為本發明第三實施例的用於控制拉曼光譜儀的裝置的第五模式模組的第五模式流程圖。Fig. 11 is a flow chart of the fifth mode of the fifth mode module of the device for controlling a Raman spectrometer according to the third embodiment of the present invention.

1:影像擷取分析單元 1: Image capture and analysis unit

2:處理單元 2: Processing unit

3:人機介面單元 3: Human-machine interface unit

4:載物控制單元 4:Load control unit

5:雷射量測控制單元 5: Laser measurement control unit

D:用於控制拉曼光譜儀的裝置 D: The device used to control the Raman spectrometer

Claims (7)

一種用於控制拉曼光譜儀的裝置,其包括:一影像擷取分析單元,用於獲取一待測物的一影像資訊,並將所述影像資訊分為多個區塊,每一區塊具有對應的一區塊資訊;一處理單元,電性連接所述影像擷取分析單元,所述處理單元將其中一區塊資訊與一預定影像資訊數值範圍或門檻值比對以決定對應的區塊是否具有第一優先分析等級;一人機介面單元,電性連接所述影像擷取分析單元及所述處理單元,所述人機介面單元針對具有所述第一優先分析等級的各個區塊分別接收一使用者輸入,以紀錄各個區塊是否具有第二優先分析等級;及一載物控制單元,電性連接所述人機介面單元,並針對具有所述第二優先分析等級的區塊控制所述待測物之位置,並使具有所述第二優先分析等級的區塊進行拉曼光譜檢測;其中,所述處理單元將所述區塊資訊與所述預定影像資訊數值範圍或門檻值比對以決定對應的區塊是否具有所述第一優先分析等級時,當所述區塊資訊落在所述預定影像資訊數值範圍時,所述處理單元決定對應的區塊具有所述第一優先分析等級,當所述區塊資訊未落在所述預定影像資訊數值範圍時,所述處理單元決定對應的區塊不具有所述第一優先分析等級。 A device for controlling a Raman spectrometer, which includes: an image capture and analysis unit, used to acquire an image information of an object to be measured, and divide the image information into multiple blocks, each block has Corresponding block information; a processing unit electrically connected to the image capture and analysis unit, the processing unit compares one block information with a predetermined image information value range or threshold value to determine the corresponding block Whether it has the first priority analysis level; a man-machine interface unit is electrically connected to the image capture analysis unit and the processing unit, and the man-machine interface unit receives each block with the first priority analysis level respectively a user input to record whether each block has a second priority analysis level; and a loading control unit electrically connected to the man-machine interface unit and controlling all blocks with the second priority analysis level The location of the object to be detected, and make the block with the second priority analysis level to perform Raman spectrum detection; wherein, the processing unit compares the block information with the predetermined image information value range or threshold value When determining whether the corresponding block has the first priority analysis level, when the block information falls within the predetermined image information value range, the processing unit determines that the corresponding block has the first priority An analysis level, when the block information does not fall within the predetermined value range of the image information, the processing unit determines that the corresponding block does not have the first priority analysis level. 一種用於控制拉曼光譜儀的裝置,其包括:一影像擷取分析單元,用於獲取一待測物的一影像資訊,並將所述影像資訊分為多個區塊,每一區塊具有對應的一區塊資訊;一處理單元,電性連接所述影像擷取分析單元,所述處理單 元將其中一區塊資訊與一預定影像資訊數值範圍或門檻值比對以決定對應的區塊是否具有第一優先分析等級;一人機介面單元,電性連接所述影像擷取分析單元及所述處理單元,所述人機介面單元針對具有所述第一優先分析等級的各個區塊分別接收一使用者輸入,以紀錄各個區塊是否具有第二優先分析等級;及一載物控制單元,電性連接所述人機介面單元,並針對具有所述第二優先分析等級的區塊控制所述待測物之位置,並使具有所述第二優先分析等級的區塊進行拉曼光譜檢測;其中,所述人機介面單元包括一第一模式模組與一第二模式模組,所述第一模式模組包括一第一模式;在所述第一模式下,所述第一模式模組針對具有所述第一優先分析等級的各個區塊提供一第一指示給一使用者,所述第一模式模組針對一對應所述第一指示的使用者輸入對應地自動記錄各個區塊是否具有所述第二優先分析等級;所述第二模式模組包括一第二模式,在所述第二模式下,所述第二模式模組針對所述使用者所決定的各個區塊是否具有所述第一優先分析等級提供一第二指示給所述使用者,所述第二模式模組針對一對應所述第二指示的使用者輸入對應地決定是否記錄所述使用者所決定的各個區塊是否具有所述第二優先分析等級。 A device for controlling a Raman spectrometer, which includes: an image capture and analysis unit, used to acquire an image information of an object to be measured, and divide the image information into multiple blocks, each block has A corresponding piece of block information; a processing unit electrically connected to the image capture and analysis unit, the processing unit The unit compares one of the block information with a predetermined image information value range or threshold value to determine whether the corresponding block has the first priority analysis level; a man-machine interface unit is electrically connected to the image capture analysis unit and the The processing unit, the man-machine interface unit respectively receives a user input for each block with the first priority analysis level to record whether each block has a second priority analysis level; and a load control unit, Electrically connect the man-machine interface unit, and control the position of the object under test for the block with the second priority analysis level, and make the block with the second priority analysis level perform Raman spectrum detection ; Wherein, the man-machine interface unit includes a first mode module and a second mode module, and the first mode module includes a first mode; in the first mode, the first mode The module provides a first indication to a user for each block with the first priority analysis level, and the first mode module automatically records each area correspondingly to a user input corresponding to the first indication Whether the block has the second priority analysis level; the second mode module includes a second mode, in the second mode, the second mode module is for each block determined by the user Whether the first priority analysis level provides a second indication to the user, the second mode module correspondingly determines whether to record the user's decision in response to a user input corresponding to the second indication Whether each block of has the second priority analysis level. 如請求項2所述的用於控制拉曼光譜儀的裝置,還包括:一雷射量測控制單元,電性連接所述人機介面單元及所述載物控制單元。 The device for controlling a Raman spectrometer according to claim 2 further includes: a laser measurement control unit electrically connected to the man-machine interface unit and the object control unit. 如請求項3所述的用於控制拉曼光譜儀的裝置,其中,所述人機介面單元包括一第三模式模組與一第四模式模組;所述第三模式模組包括一第三模式,在所述第三模式下,所述第 三模式模組針對具有所述第一優先分析等級的各個區塊提供一第三指示給所述使用者,所述第三模式模組針對一對應所述第三指示的使用者輸入對應地自動記錄各個區塊是否具有所述第二優先分析等級並將所述具有第二優先分析等級的區塊資訊傳送至所述雷射量測控制單元,所述雷射量測控制單元分析決定所述具有第二優先分析等級的區塊資訊是否具有第三優先分析等級並傳送所述具有第三優先分析等級的區塊資訊至所述第三模式模組,所述第三模式模組對應地自動記錄各個區塊是否具有所述第三優先分析等級;所述第四模式模組包括一第四模式,在所述第四模式下,所述第四模式模組將各個所述使用者所決定具有所述第二優先分析等級的區塊資訊傳送至所述雷射量測控制單元,所述雷射量測控制單元分析決定所述具有第二優先分析等級的區塊資訊是否具有所述第三優先分析等級並傳送至所述第四模式模組,所述第四模式模組針對所述使用者所決定的各個區塊是否具有第三優先分析等級提供一第四指示給所述使用者,所述第四模式模組針對一對應第四指示的使用者輸入對應地記錄各個區塊是否具有第三優先分析等級。 The device for controlling a Raman spectrometer as described in claim 3, wherein the man-machine interface unit includes a third mode module and a fourth mode module; the third mode module includes a third mode, in the third mode, the first The three-mode module provides a third indication to the user for each block with the first priority analysis level, and the third mode module correspondingly automatically responds to a user input corresponding to the third indication. recording whether each block has the second priority analysis level and sending the block information with the second priority analysis level to the laser measurement control unit, and the laser measurement control unit analyzes and determines the Whether the block information with the second priority analysis level has the third priority analysis level and transmit the block information with the third priority analysis level to the third mode module, and the third mode module automatically correspondingly record whether each block has the third priority analysis level; the fourth mode module includes a fourth mode, in the fourth mode, the fourth mode module will The block information with the second priority analysis level is sent to the laser measurement control unit, and the laser measurement control unit analyzes and determines whether the block information with the second priority analysis level has the first Three priority analysis levels are sent to the fourth mode module, and the fourth mode module provides a fourth indication to the user whether each block determined by the user has a third priority analysis level , the fourth mode module correspondingly records whether each block has the third priority analysis level for a user input corresponding to a fourth instruction. 如請求項2至4中任一項所述的用於控制拉曼光譜儀的裝置,還包括:一清潔控制單元,電性連接所述人機介面單元。 The device for controlling a Raman spectrometer according to any one of claims 2 to 4, further comprising: a cleaning control unit electrically connected to the man-machine interface unit. 如請求項5所述的用於控制拉曼光譜儀的裝置,其中,所述清潔控制單元執行一自動控制以清潔所述拉曼光譜儀內的一檢測空間。 The device for controlling a Raman spectrometer according to claim 5, wherein the cleaning control unit performs an automatic control to clean a detection space in the Raman spectrometer. 如請求項5所述的用於控制拉曼光譜儀的裝置,其中,所述人機介面單元包括一第五模式模組,所述第五模式模組包括一第五模式,在所述第五模式下,所述第五模式模組針對承 載所述待測物的一基板的一使用次數、所述拉曼光譜儀的一載台的一進出拉曼光譜儀的所述檢測空間的次數、或所述拉曼光譜儀持續啟動狀態的時間提供一第五指示給所述使用者,所述第五模式模組針對一對應第五指示的使用者輸入對應地決定是否清潔所述拉曼光譜儀的所述檢測空間。 The device for controlling a Raman spectrometer as described in claim 5, wherein the man-machine interface unit includes a fifth mode module, and the fifth mode module includes a fifth mode, and in the fifth mode, the fifth mode module for bearing The number of times a substrate carrying the analyte is used, the number of times a stage of the Raman spectrometer enters and exits the detection space of the Raman spectrometer, or the time for which the Raman spectrometer continues to start the state provides a The fifth instruction is given to the user, and the fifth mode module correspondingly determines whether to clean the detection space of the Raman spectrometer according to a user input corresponding to the fifth instruction.
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