TWI795620B - Wearable device for flexible sensing patch - Google Patents

Abstract

A wearable device having a flexible sensing patch, wherein the device comprises a PPG sensor, a housing and an extension cable, wherein the extension connecting line is used for electrically connecting the PPG sensor and the outer casing so that the PPG sensor does not directly move when the outer casing moves. The PPG sensor comprises an organic light emitting diode, an organic photodiode and a flexible substrate, wherein the organic light emitting diode is used to emit a light source; The organic photodiode is configured to receive the light source and generate an optical signal; the flexible substrate is configured to place the organic light emitting diode and the organic photodiode. The housing comprises a microprocessor, a battery and a circuit board, wherein the microprocessor is configured to analyze the optical signal by using an algorithm; the battery is used to supply the microprocessor power; the circuit board is used to place the microprocessor and the battery.

Description

Wearable device with flexible sensing patch

The invention relates to a wearable device with a flexible sensing patch.

Affected by the way of life in recent years, chronic diseases (such as heart disease, diabetes, stroke and cancer) have replaced acute infectious diseases as modern civilization diseases that plague many people. In addition to damaging personal health, chronic diseases will also impose a heavy burden on the family economy and national medical expenditure. Therefore, the prevention and treatment of chronic diseases has become an issue that countries all over the world must face. At present, hospitals have a variety of chronic disease detection methods, but many patients often have passed the time for early treatment when chronic diseases are detected. Therefore, if regular detection can be implemented at any place and time, the effect of early detection and early treatment can be brought into play.

Therefore, at present, major technology factories in the world are launching portable or wearable personal health detection devices one after another, and the detection devices for detecting cardiovascular diseases occupy most of the market. Because according to the statistics of the World Health Organization, coronary artery disease and stroke rank first and second in the top ten causes of death in the world, respectively. In Taiwan, although cancer still occupies the top ten causes of death, heart disease and cerebrovascular disease occupy the second and third places, and among the top ten causes of death, half of them are related to cardiovascular diseases, and the combined deaths The percentage exceeds the number one cancer, which shows the seriousness of this threat. Therefore, wearable detection devices for detecting cardiovascular diseases are springing up.

At present, the main technology used in wearable detection devices for detecting cardiovascular diseases is blood pulsation volume change (Photoplethysmography, PPG) (or called photoplethysmography), which uses Irradiate the skin surface with infrared light sensing elements, use the principle of blood absorbing light energy, and record the signal induced by the change of light. When the heart beats periodically, the blood volume will also change periodically, so the infrared light received by the light sensing element will also induce voltage and generate a signal with the change of blood volume, so the photoplethysmography (PPG) ) The amplitude of the signal will change in proportion to the blood entering and leaving the tissue. The photoplethysmography signal is easy to obtain. Compared with other instruments, the photoplethysmography method has the advantages of portable equipment, simple operation, non-invasiveness, high affinity and low cost, so many scholars have invested in research.

However, most known wearable devices that use photoplethysmography physiological sensors to detect cardiovascular diseases today have problems of poor signal quality, inflexible use, and poor patch fixation. The reason is that the sensor and the shell used in wearable devices are fixed together. Therefore, when the human body is in motion, the movement of the shell will have a linkage relationship with the sensor, so that there is a gap between the human body and the sensor. The relative displacement of the sensor causes interference noise, thus causing motion artifact (Motion artifact) noise between the human body and the sensor. And sometimes when the patch is attached to the expected position of the wrist artery, because the sensor is made of hard material, the structure of the sensor cannot change with the structure of the wrist, resulting in insufficient adhesion of the patch and the detection of the sensor. to the problem of environmental noise. It may also be applied to other wrist positions because the user does not know the correct position of the artery, thus causing the sensor to detect signals generated by other non-wrist arteries.

Therefore, in order to solve the above problems, this case proposes a solution of a wearable device with a flexible sensing patch. Wherein the device comprises a photoplethysmography sensor, a microprocessor module and an extension connection line, and the extension connection line is used to electrically connect the photoplethysmography sensor and the microprocessor module so as to When the microprocessor module moves, it does not directly drive the photoplethysmography sensor to move. The photoplethysmography sensor includes an organic light emitting diode (OLED), an organic photodiode (OPD) and a flexible substrate, wherein the organic light emitting diode is used to emit light source; the organic photodiode is used to receive the light source and generate light signals; the flexible substrate is used to place the organic light emitting diode and the organic photodiode. The microprocessor module includes a casing, a microprocessor, a battery and a circuit board, wherein the microprocessor is used to analyze the optical signal using an algorithm; the battery is used to provide power to the microprocessor; the circuit board is used to place the microprocessor and the battery.

According to an embodiment, the organic light-emitting diode, the organic photodiode and the flexible substrate included in the photoplethysmography sensor are all made of soft materials, which can be bent according to the structure of the skin surface. To fully fit the wrist structure so that the gap between the patch and the hand can be closer and closer to the skin for good measurements of motion artifact noise cancellation.

According to an embodiment, the organic light-emitting diodes and the organic photodiodes in the photoplethysmography sensor are arranged in an array arrangement, and the array arrangement is a method suitable for detecting cardiovascular diseases. Array arrangement.

According to an embodiment, the above-mentioned photoplethysmography sensor can be in the shape of a strip and attached to the entire wrist skin surface, and the organic light-emitting diodes and organic photodiodes on the photoplethysmography sensor can be arrayed The arrangement extends over the entire photoplethysmographic sensor so that all signals on the skin surface of the wrist can be detected.

According to an embodiment, the relative distance between the organic light emitting diode and the organic photodiode is related to the wavelength of the light source, and the longer the wavelength of the light source is, the larger the relative distance between the elements is.

According to an embodiment, the above-mentioned algorithm is a calculation method specially used for analyzing cardiac arrhythmia signals. The algorithm can use the strongest signal as the arterial signal, and the rest as reference signals to achieve a noise elimination mechanism.

According to an embodiment, the above-mentioned microprocessor is used to generate a cardiac arrhythmia (Atrial fibrillation, AF) graph, which is an electrocardiogram used to detect atrial fibrillation, and the electrocardiogram can be used to check cardiovascular diseases.

A wearable device with a flexible sensing patch, wherein the device includes a photoplethysmography sensor and a microprocessor module, wherein the surface of the photoplethysmography sensor has an adhesive substance for sticking to the skin On the surface, the microprocessor module is electrically connected with the photoplethysmography sensor by an extension cable. Therefore, the microprocessor module can be separated from the photoplethysmography sensor to prevent the photoplethysmography sensor from moving due to the movement of the microprocessor module.

According to an embodiment, the relative position between the microprocessor module and the photoplethysmography sensor may have a relative displacement, but the relative position between the photoplethysmography sensor and the skin surface is not. Relative displacement, so motion artifact noise can be avoided.

According to an embodiment, the above-mentioned motion artifact noise is a kind of noise interference generated in the motion state of the human body, because the motion state causes the displacement of the photoplethysmography sensor, so that the photoplethysmography sensor detects Irregular signal, so that the arrhythmia graph appears irregular beating graphics.

100, 200, 300: photoplethysmography sensor

101, 301: organic light-emitting diodes

103, 303: Organic photodiodes

105, 305: flexible substrate

110, 210, 310: Microprocessor module

112, 212, 312: Shell

111, 211, 311: battery

113, 213, 313: microprocessor

115, 215, 315: circuit board

120, 220, 320: extension cable

201: light emitting diode

203: Photodiode

205: Rigid substrate

Figure 1 is a schematic diagram of a flexible OLED-OPD sensor patch wearable device

Figure 2 is a schematic diagram of the LED-PD sensing patch wearable device

FIG. 3 is a schematic diagram of a flexible OLED-OPD extended sensing patch wearable device.

In order to make the purpose, technical solutions and advantages of this creation clearer, the creation will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, but not to limit the present invention.

Example 1

Please refer to FIG. 1 , the invention is a wearable device with a flexible sensing patch, including a photoplethysmography sensor 100 , a microprocessor module 110 and an extension cable 120 . Wherein the photoplethysmography sensor 100 is used to emit light source and receive light source, and generate a light signal, the surface of the photoplethysmography sensor 100 has a viscous substance for sticking on the human skin, and the microprocessing The processor module 110 has a casing 112, and the casing 112 is a hard material for fixing on an object, for example, fixing the microprocessor module 110 on a wrist or an arm of a human body. The photoplethysmography sensor 100 is separated from the microprocessor module 110, and the microprocessor module 110 and the photoplethysmography sensor 100 are electrically connected through the extension connection line 120, and the extension connection line 120 is used for transmitting the light signal generated by the photoplethysmography sensor 100 to the microprocessor module 110 . Therefore, when the microprocessor module 110 has a relative displacement with the wrist, the photoplethysmography sensor 100 will not have a relative displacement with the wrist along with the microprocessor module 110, which can be used to avoid motion artifacts. Shadow noise, wherein the motion artifact noise is a kind of noise interference generated in a state of human body movement.

Please refer to FIG. 1 , the photoplethysmography sensor 100 includes an organic light emitting diode 101 , an organic photodiode 103 and a flexible substrate 105 . Wherein the organic light emitting diode 101 is a kind of soft material, which can be bent according to the structure of the wrist, so as to fit the wrist completely, and can emit light. The organic photodiode 103 is a kind of soft material, which can be bent according to the structure of the wrist , to receive the light source. The organic light emitting diode 101 and the organic photodiode 103 are placed on the flexible substrate 105 for fixing the relative positions of the organic light emitting diode 101 and the organic photodiode 103 and arranged in an array The relative positions are arranged in an array arrangement, wherein the relative distance between the array arrangements is related to the wavelength of the light source. The flexible substrate 105 is a soft material, which can be bent according to the structure of the wrist so as to fit the wrist completely.

Please refer to FIG. 1 , the microprocessor module 110 includes a housing 112 , a battery 111 , a microprocessor 113 and a circuit board 115 . Wherein the battery 111 can be a flexible lithium ceramic battery, the battery is used to provide electric energy to the microprocessor 113, and the microprocessor 113 is used to receive the light signal transmitted from the photoplethysmography sensor 100, The microprocessor 113 calculates and analyzes the light signal using an algorithm specially used for cardiac arrhythmia, and obtains a cardiac arrhythmia map. The battery 111 and the microprocessor 113 are placed on the circuit board 115 for fixing the relative positions of the battery 111 and the microprocessor 113 . The shell 112 is used to cover the battery 111 , the microprocessor 113 and the circuit board 115 so that the above-mentioned components are fixed on the wrist.

Please refer to FIG. 1 , the organic light emitting diode 101 and the organic photodiode 103 are placed on the flexible substrate 105 . The organic light emitting diode 101 is used to emit a light source, and the light source penetrates the surface layer of the skin to irradiate capillaries or arteries. The blood flow of the capillaries or arteries determines the amount of reflected light of the light source. After receiving the reflected light signal, the photoplethysmography sensor 100 generates a light signal, and the light signal is sent to the microprocessor 113 in the microprocessor module 110 through the extension cable 120 .

Please refer to FIG. 1 , the battery 111 and the microprocessor 113 are placed on the circuit board 115 . The battery 111 can be a flexible lithium ceramic battery. The battery 111 is used to provide power to the microprocessor 113. The microprocessor 113 uses an algorithm to analyze the light generated from the photoplethysmography sensor 110. signal, the algorithm is an algorithm for mapping the optical signal into a fibrillation map, wherein the fibrillation map is an electrocardiogram used to detect arrhythmias.

Example 2

Please refer to FIG. 2 , the invention is a wearable device with a flexible sensing patch, including a photoplethysmography sensor 200 , a microprocessor module 210 and an extension cable 220 . Wherein the photoplethysmography sensor 200 is used to emit light source and receive light source, and generate light signal, the light body The surface of the plethysmography sensor 200 has an adhesive substance for sticking on the human skin, and the microprocessor module 210 has a casing 212, and the casing 212 is a hard material for fixing on an object, for example The microprocessor module 210 is fixed on the wrist or arm of the human body. The photoplethysmography sensor 200 is separated from the microprocessor module 210, and the microprocessor module 210 and the photoplethysmography sensor 200 are electrically connected through the extension connection line 220, and the extension connection line 220 is used for transmitting the light signal generated by the photoplethysmography sensor 200 to the microprocessor module 210 . Therefore, when the microprocessor module 210 has a relative displacement with the wrist, the photoplethysmography sensor 200 will not have a relative displacement with the wrist along with the microprocessor module 210, which can be used to avoid motion artifacts. Shadow noise, wherein the motion artifact noise is a kind of noise interference generated in a state of human body movement.

Please refer to FIG. 2, the photoplethysmography sensor 200 includes a light-emitting diode 201, a photodiode 203 and a rigid substrate 205. The light-emitting diode 201 is a rigid material, which can The polar body 201 is made very small so as to fit roughly with the arm or wrist, and can emit a light source. The photodiode 203 is a hard material for receiving the light source. The light emitting diode 201 and the photodiode The body 203 is placed on the rigid substrate 205, and the rigid substrate 205 can be a hard glass material, which is used to fix the relative positions of the light emitting diode 201 and the photodiode 203, and arrange the light emitting diodes 201 in an array arrangement. Relative positions, wherein the relative distance between the array arrangements is related to the wavelength of the light source.

Please refer to FIG. 2 , the microprocessor module 210 includes a housing 212 , a battery 211 , a microprocessor 213 and a circuit board 215 . Wherein the battery 211 can be a flexible lithium ceramic battery, the battery is used to provide electric energy to the microprocessor 213, and the microprocessor 213 is used to receive the light signal transmitted from the photoplethysmography sensor 200, The microprocessor 213 calculates and analyzes the light signal using an algorithm specially used for cardiac arrhythmia, and obtains a cardiac arrhythmia map. The battery 211 and the microprocessor 213 are placed in the circuit The board 215 is used to fix the relative positions of the battery 211 and the microprocessor 213 . The casing 212 is used to cover the battery 211 , the microprocessor 213 and the circuit board 215 so that the above-mentioned components are fixed on the wrist.

Please refer to FIG. 2 , the light emitting diode 201 and the photodiode 203 are placed on the rigid substrate 205 . The light emitting diode 201 is used to emit a light source, and the light source penetrates the surface layer of the skin to irradiate capillaries or arteries. The blood flow of the capillaries or the arteries determines the amount of reflected light of the light source. After the light signal is received, the photoplethysmography sensor 200 generates a light signal, and the light signal is sent to the microprocessor 213 in the microprocessor module 210 through the extension cable 220 .

Please refer to FIG. 2 , the battery 211 and the microprocessor 213 are placed on the circuit board 215 . The battery 211 can be a flexible lithium ceramic battery. The battery 211 is used to provide power to the microprocessor 213. The microprocessor 213 uses an algorithm to analyze the light generated from the photoplethysmography sensor 210. signal, the algorithm is an algorithm for mapping the optical signal into a fibrillation map, wherein the fibrillation map is an electrocardiogram used to detect arrhythmias.

Example 3

Please refer to Figure 3, this creation is a wearable device with a flexible sensing patch, including a photoplethysmography sensor 300, a microprocessor module 310 and an extension cable 320, wherein the photoplethysmography The tracing sensor 300 is used for sensing and receiving the light source. The photoplethysmography sensor 300 has an adhesive substance on its surface, which is used to stick on the human skin. All the signals on the surface of the wrist skin, so that when the user detects the arteries and cannot find the arteries, he can first detect all the signals on the wrist, and then use the algorithm to use the strongest signal as the arterial signal, and other signals as reference signals. Used as a noise cancellation mechanism. And this microprocessor module 310 has shell 312, and this shell 312 is a It is a hard material for fixing on an object, for example fixing the microprocessor module 310 on the wrist or arm of the human body. The photoplethysmography sensor 300 is separated from the microprocessor module 310, and the microprocessor module 310 and the photoplethysmography sensor 300 are electrically connected through the extension connection line 320, and the extension connection line 320 is used for transmitting the light signal generated by the photoplethysmography sensor 300 to the microprocessor module 310 . Therefore, when the microprocessor module 310 has a relative displacement with the wrist, the photoplethysmography sensor 300 will not have a relative displacement with the wrist along with the microprocessor module 310, which can be used to avoid motion artifacts. Shadow noise, wherein the motion artifact noise is a kind of noise interference generated in a state of human body movement.

Please refer to FIG. 3, the photoplethysmography sensor 300 includes an organic light emitting diode 301, an organic photodiode 303, and a flexible substrate 305. The organic light emitting diode 301 is a flexible material that can be used according to The structure of the wrist is bent to fit the wrist completely and emit light. The organic photodiode 303 is a soft material that can be bent according to the structure of the wrist to receive the light. The organic light emitting diode 301 and the organic photodiode 303 are placed on the flexible substrate 305 for fixing the relative positions of the organic light emitting diode 301 and the organic photodiode 303 and arranged in an array The relative positions are arranged in a manner, wherein the relative distance between the array arrangements is related to the wavelength of the light source. The organic light-emitting diodes 301 and organic photodiodes 303 on the photoplethysmography sensor 300 can extend to the entire photoplethysmography sensor 300 in an array arrangement, so that the skin surface of the wrist can be detected. For all signals on the wrist, the flexible substrate 305 is a soft material that can be bent according to the structure of the wrist so as to fit the wrist completely.

Please refer to FIG. 3 , the microprocessor module 310 includes a housing 312 , a battery 311 , a microprocessor 313 and a circuit board 315 . Wherein the battery 311 can be a flexible lithium ceramic battery, and the battery is used to provide electric energy to the microprocessor 313, and the microprocessor 313 is used to receive the sensor from the photoplethysmography method. The light signal transmitted by the detector 300, the microprocessor 313 calculates and analyzes the light signal using an algorithm specially used for cardiac arrhythmia, and obtains a cardiac arrhythmia map. The battery 311 and the microprocessor 313 are placed on the circuit board 315 for fixing the relative positions of the battery 311 and the microprocessor 313 . The shell 312 is used to cover the battery 311 , the microprocessor 313 and the circuit board 315 so that the above-mentioned components are fixed on the wrist.

Please refer to FIG. 3 , the organic light emitting diode 301 and the organic photodiode 303 are placed on the flexible substrate 305 . The organic light emitting diode 301 is used to emit a light source, and the light source penetrates the surface layer of the skin to irradiate capillaries or arteries. The blood flow of the capillaries or arteries determines the amount of reflected light of the light source. After receiving the reflected light signal, the photoplethysmography sensor 300 generates a light signal, and the light signal is sent to the microprocessor 313 in the microprocessor module 310 through the extension connection line 320 .

Please refer to FIG. 3 , the battery 311 and the microprocessor 313 are placed on the circuit board 315 . The battery 311 can be a flexible lithium ceramic battery for providing electric energy to the microprocessor 313, and the microprocessor 313 uses an algorithm to analyze the light signal generated by the photoplethysmography sensor 310, the algorithm The method is a calculation method for drawing the optical signal into a heart rhythm fibrillation map, which is to use the detected stronger signal as the arterial signal, use the weaker signal as the reference signal, and use the reference signal mixed with the arterial signal cancel to achieve a noise cancellation mechanism and obtain a fibrillation map, wherein the fibrillation map is an electrocardiogram used to detect cardiac arrhythmias.

To sum up, the present invention proposes a wearable device with a flexible sensing patch, the photoplethysmography sensor of the device is separated from the microprocessor module, and the surface of the photoplethysmography sensor uses The viscous substance sticks to the surface of the skin, and it is only connected with the microprocessor module by an extension cable, so when the microprocessor module and the wrist have relative displacement, the photoplethysmography sensor will not Due to the linkage of the microprocessor module, there is a relative displacement with the wrist, so it can avoid motion artifacts and noises in the cardiac arrhythmia and fibrillation images. In addition, the photoplethysmography sensor can be made of soft material, which can be bent with the structure of the wrist to avoid the detection of environmental noise caused by insufficient adhesion. And the photoplethysmography sensor can be pasted on the entire wrist skin surface in the shape of a strip, and the organic light-emitting diodes and organic photodiodes on the photoplethysmography sensor can be extended in an array arrangement To the entire photoplethysmography sensor, so it can detect all the signals on the surface of the wrist skin, and use the algorithm to use the stronger signal as the arterial signal, and the rest of the signal as the reference signal, which can have the effect of noise elimination mechanism. Therefore, the wearable device with the flexible sensing patch can remove the motion artifact noise and obtain the arrhythmia map with less noise.

However, the illustrations and descriptions disclosed above are only preferred embodiments of the present invention, and are not intended to limit the implementation of the present invention. Those who are familiar with the art generally make changes based on the spirit of the present invention Or modification, should be covered in the scope of the patent application of the following case.

100: Photoplethysmography sensor

101: Organic Light Emitting Diodes

103:Organic photodiode

105: Flexible substrate

110: Microprocessor module

112: shell

111: battery

113: Microprocessor

115: circuit board

120: extension cable

Claims (9)

A wearable device with a flexible sensing patch, comprising: a photoplethysmography sensor, the surface of the photoplethysmography sensor has an adhesive substance for sticking to the skin of a human body, the photoplethysmography sensor The tracing method sensor includes: an organic light emitting diode for emitting a light source; an organic photodiode for receiving the light source and generating a light signal; and a flexible substrate for placing the organic light emitting diode The diode and the organic photodiode, wherein the organic light-emitting diode, the organic photodiode and the flexible substrate are made of soft materials for bending according to the structure of the skin surface of the human body; a micro The processor module is fixed on the wrist or shoulder of the human body, and is separated from the position of the photoplethysmography sensor and does not overlap. The microprocessor module includes: a shell for fixing the microprocessor The processor module is on the wrist or shoulder of the human body: a microprocessor is used to analyze the light signal using an algorithm; a battery is used to provide power to the microprocessor; and a circuit board is used to placing the microprocessor and the battery; and an extension cable for electrically connecting the photoplethysmography sensor and the microprocessor module, whereby when the microprocessor module moves, It does not directly drive the photoplethysmography sensor to move, wherein the relative position between the microprocessor module and the photoplethysmography sensor has a relative displacement, but the photoplethysmography sensor and the photoplethysmography sensor There is no relative displacement between the skin surfaces to avoid a motion artifact noise. The wearable device with a flexible sensing patch as claimed in Claim 1, wherein the battery is a flexible lithium ceramic battery. The wearable device with a flexible sensing patch as described in Claim 1, wherein the organic light-emitting diode and the organic photodiode in the photoplethysmography sensor are arranged in an array arrangement . The wearable device with a flexible sensing patch as claimed in Claim 1, wherein the relative distance between the organic light emitting diode and the organic photodiode is related to the wavelength of the light source. The wearable device with a flexible sensing patch as described in Claim 1, wherein the algorithm is an algorithm specially used for analyzing cardiac arrhythmia signals. The wearable device with the flexible sensing patch as claimed in claim 1, wherein the microprocessor is used to generate a cardiac arrhythmia, and the cardiac arrhythmia is an electrocardiogram for detecting atrial fibrillation. The wearable device with a flexible sensing patch as claimed in Claim 1, wherein the motion artifact noise is a noise interference generated in a state of human body motion. The wearable device with a flexible sensing patch as described in claim 1, wherein the photoplethysmography sensor further has a strip shape, which is used to stick on the skin surface of the entire wrist or shoulder . The wearable device with a flexible sensing patch as described in Claim 8, further includes when the photoplethysmography sensor is attached to the skin surface of the entire wrist or shoulder in the strip shape to receive the patch When there are multiple signals covering the area, the microprocessor will detect the strongest signal among the signals as an arterial signal through the algorithm, wherein the signals that are excluded from the strongest signal will be used as a plurality of reference signals. as a basis for judging noise.

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