TWI778456B - Tangential flow filtration module and tangential flow filtration assembly - Google Patents

Tangential flow filtration module and tangential flow filtration assembly Download PDF

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TWI778456B
TWI778456B TW109141211A TW109141211A TWI778456B TW I778456 B TWI778456 B TW I778456B TW 109141211 A TW109141211 A TW 109141211A TW 109141211 A TW109141211 A TW 109141211A TW I778456 B TWI778456 B TW I778456B
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flange
joint
unit
tangential flow
plate units
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TW109141211A
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TW202220745A (en
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洪正翰
吳俊穆
劉宗鑫
曾柏翰
黃堯焜
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財團法人金屬工業研究發展中心
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Abstract

A tangential flow filtration module includes plural plate units serially connected in sequence. Each of the plate units includes a main body, a first combing portion, a second combing portion, a first flange and a second flange. The main body has a first side surface, a second side surface and a through hole. The first side surface is opposite to the second side surface, and the through hole extends from the first side surface to the second side surface. The first combing portion and the second combing portion respective protrude from the first side surface and the second side surface and surround the through hole. A first combing portion of one of the plate units abuts on the second combing portion of another one of the plate units adjacent to the one of the plate units, so that a sieving structure can be formed by the first flange of the one of the plate units and the second flange of the another one of the plate units adjacent to the one of the plate units.

Description

切向流過濾模組及切向流過濾組件Tangential flow filter module and tangential flow filter assembly

本發明是有關於一種過濾模組,且特別是有關於一種切向流過濾模組以及使用此切向流過濾模組之切向流過濾組件。The present invention relates to a filter module, and more particularly, to a tangential flow filter module and a tangential flow filter assembly using the tangential flow filter module.

近年來,微球生產與應用日益廣泛,且微球的應用基本需求為粒徑的均一性,故通常會使用篩網來過篩微球,以獲得尺寸相近的微球。In recent years, the production and application of microspheres have become increasingly widespread, and the basic requirement for the application of microspheres is the uniformity of particle size, so a screen is usually used to sieve the microspheres to obtain microspheres of similar size.

然而,目前常見的篩網通常都是透過編織製成,故篩孔尺寸難以掌握,且精度不佳。此外,篩網使用時間久了常會發生篩孔阻塞,而嚴重影響篩選效果。However, the common screen meshes are usually made by weaving, so the size of the screen holes is difficult to grasp and the precision is poor. In addition, when the screen is used for a long time, the screen hole will often be blocked, which will seriously affect the screening effect.

因此,本發明之一目的是在提供一種切向流過濾模組及使用此切向流過濾模組之切向流過濾組件,其可提升微球的過濾精度與效率。Therefore, one objective of the present invention is to provide a tangential flow filter module and a tangential flow filter assembly using the tangential flow filter module, which can improve the filtration precision and efficiency of microspheres.

根據本發明之上述目的,提出一種切向流過濾模組。此切向流過濾模組包含依序串接之複數個板片單元。每一個板片單元包含本體、第一接合部、第二接合部、第一凸緣及一第二凸緣。本體具有第一側面、第二側面以及穿孔,其中第一側面相對第二側面,且穿孔從第一側面貫穿至第二側面。第一接合部與第二接合部分別凸設於第一側面與第二側面。第一凸緣與第二凸緣分別凸伸於第一側面與第二側面,且環繞穿孔。其中,任一板片單元的第一接合部與相鄰之板片單元的第二接合部互相抵接,使任一板片單元的第一凸緣與相鄰之板片單元的第二凸緣共同形成微篩結構。According to the above objective of the present invention, a tangential flow filter module is proposed. The tangential flow filter module includes a plurality of plate units connected in series. Each plate unit includes a body, a first joint portion, a second joint portion, a first flange and a second flange. The body has a first side surface, a second side surface and a through hole, wherein the first side surface is opposite to the second side surface, and the through hole penetrates from the first side surface to the second side surface. The first joint portion and the second joint portion are respectively protruded from the first side surface and the second side surface. The first flange and the second flange respectively protrude from the first side surface and the second side surface, and surround the through hole. Wherein, the first joint part of any plate unit and the second joint part of the adjacent plate unit are in contact with each other, so that the first flange of any plate unit and the second protrusion of the adjacent plate unit The edges together form a microsieve structure.

依據本發明之一實施例,其中上述之第一凸緣具有第一外表面,第一外表面是從第一側面往穿孔之中心軸的方向延伸至第一凸緣之頂端。第二凸緣具有第二外表面,第二外表面是從第二側面往穿孔之中心軸的方向延伸至第二凸緣之頂端。任一板片單元的第一凸緣之第一外表面與相鄰之板片單元的第二凸緣之第二外表面共同形成寬度漸變之微篩結構。According to an embodiment of the present invention, the first flange has a first outer surface, and the first outer surface extends from the first side surface toward the center axis of the through hole to the top of the first flange. The second flange has a second outer surface, and the second outer surface extends from the second side to the top of the second flange in the direction of the central axis of the through hole. The first outer surface of the first flange of any plate unit and the second outer surface of the second flange of the adjacent plate unit together form a micro-sieve structure with a gradual width.

依據本發明之一實施例,其中上述之第一接合部與第一凸緣之間具有第一高度差。第二接合部與第二凸緣之間具有第二高度差。其中第一高度差與第二高度差共同形成微篩結構之開口寬度。According to an embodiment of the present invention, there is a first height difference between the first joint portion and the first flange. There is a second height difference between the second engaging portion and the second flange. The first height difference and the second height difference together form the opening width of the micro-sieve structure.

依據本發明之一實施例,其中上述之每一個板片單元之表面鍍有疏水性膜或光滑膜。According to an embodiment of the present invention, the surface of each of the above-mentioned plate units is coated with a hydrophobic film or a smooth film.

依據本發明之一實施例,其中上述之切向流過濾模組更包含第一接頭單元及第二接頭單元。第一接頭單元與第二接頭單元分別包含裝配塊本體、管部以及接合部。裝配塊本體具有外側面、裝配面以及通孔,其中外側面相對裝配面,且通孔從外側面貫穿至裝配面。管部設置在外側面上,且連通通孔。接合部凸設於裝配面上。其中,第一接頭單元組接於板片單元中之第一個板片單元之第二接合部,且第二接頭單元組接於板片單元中之最後一個板片單元之第一接合部。According to an embodiment of the present invention, the above-mentioned tangential flow filter module further includes a first joint unit and a second joint unit. The first joint unit and the second joint unit respectively comprise an assembly block body, a pipe part and a joint part. The mounting block body has an outer side surface, a mounting surface and a through hole, wherein the outer side surface is opposite to the mounting surface, and the through hole penetrates from the outer side surface to the mounting surface. The pipe portion is provided on the outer side and communicates with the through hole. The joint portion is protruded on the assembling surface. Wherein, the first joint unit is assembled with the second joint part of the first plate unit of the plate units, and the second joint unit is assembled with the first joint part of the last plate unit of the plate units.

依據本發明之一實施例,其中上述之第一接頭單元與第二接頭單元分別更包含凸緣,凸緣凸伸於裝配面,且環繞通孔。其中,第一接頭單元的凸緣與板片單元中之第一個板片單元之第二凸緣共同形成另一微篩結構,第二接頭單元的凸緣與板片單元中之最後一個板片單元之第一凸緣共同形成又一微篩結構。According to an embodiment of the present invention, the first joint unit and the second joint unit further include flanges, respectively, and the flanges protrude from the mounting surface and surround the through holes. Wherein, the flange of the first joint unit and the second flange of the first plate unit in the plate unit together form another micro-sieve structure, and the flange of the second joint unit and the last plate of the plate unit The first flanges of the sheet units together form yet another microsieve structure.

依據本發明之一實施例,其中上述之切向流過濾模組更包含彈性元件,裝設於相鄰之兩板片單元之些本體間。According to an embodiment of the present invention, the above-mentioned tangential flow filter module further includes an elastic element installed between the bodies of the two adjacent plate units.

根據本發明之上述目的,另提出一種切向流過濾組件。此切向流過濾組件包含上述之切向流過濾模組以及外管。外管具有第一端、相對第一端之第二端、以及容置空間。其中,切向流過濾模組設置在容置空間中,且第一接頭單元的管部延伸在第一端外,第二接頭單元的管部延伸在第二端外。其中,當待過濾液體從第一接頭單元的管部流經板片單元的穿孔而往第二接頭單元的管部流動時,待過濾液體中的小於微篩結構尺寸的微球將通過微篩結構進入容置空間中。According to the above objective of the present invention, another tangential flow filter assembly is proposed. The tangential flow filter assembly includes the above-mentioned tangential flow filter module and an outer tube. The outer tube has a first end, a second end opposite to the first end, and an accommodating space. The tangential flow filter module is arranged in the accommodating space, the pipe portion of the first joint unit extends outside the first end, and the pipe portion of the second joint unit extends outside the second end. Wherein, when the liquid to be filtered flows from the pipe part of the first joint unit through the perforation of the plate unit to the pipe part of the second joint unit, the microspheres in the liquid to be filtered that are smaller than the structure size of the microsieve will pass through the microsieve The structure enters the accommodating space.

依據本發明之一實施例,上述之每一個板片單元之第一凸緣具有第一外表面,第一外表面是從第一側面往穿孔之中心軸的方向延伸至第一凸緣之頂端。上述之每一個板片單元之第二凸緣具有第二外表面,第二外表面是從第二側面往穿孔之中心軸的方向延伸至第二凸緣之頂端。任一個板片單元的第一凸緣之第一外表面與相鄰之板片單元的第二凸緣之第二外表面共同形成寬度漸變之微篩結構。According to an embodiment of the present invention, the first flange of each of the above-mentioned plate units has a first outer surface, and the first outer surface extends from the first side toward the center axis of the through hole to the top of the first flange . The second flange of each of the above-mentioned plate units has a second outer surface, and the second outer surface extends from the second side to the top of the second flange in the direction of the center axis of the through hole. The first outer surface of the first flange of any one plate unit and the second outer surface of the second flange of the adjacent plate unit together form a micro-sieve structure with a gradual width.

依據本發明之一實施例,上述之每一個板片單元之第一接合部與第一凸緣之間具有第一高度差。每一個板片單元之第二接合部與第二凸緣之間具有第二高度差。其中,第一高度差與第二高度差共同形成微篩結構之開口寬度。According to an embodiment of the present invention, there is a first height difference between the first joint portion and the first flange of each of the above-mentioned plate units. There is a second height difference between the second joint portion of each plate unit and the second flange. Wherein, the first height difference and the second height difference together form the opening width of the micro-sieve structure.

依據本發明之一實施例,上述之每一個板片單元之表面鍍有疏水性膜或光滑膜。According to an embodiment of the present invention, the surface of each of the above-mentioned plate units is coated with a hydrophobic film or a smooth film.

由上述可知,本發明主要是將模組化的板片單元堆疊形成待過濾液體流道以及微篩結構,透過搭配管線配置與加壓幫浦可達到循環式的微球篩選之目的。另一方面,利用堆疊組裝板片單元形成微篩結構的方式,可方便控制微篩結構的微粒篩選尺寸,提升整體的篩選精度。此外,模組化的板片單元除了容易量產外,板片單元本身也容易組裝與拆卸,故具有容易清洗保養之優點。As can be seen from the above, the present invention mainly stacks modular plate units to form the liquid flow channel to be filtered and the micro-sieve structure, and the purpose of circulating micro-sphere screening can be achieved by matching the pipeline configuration and the pressurized pump. On the other hand, by stacking and assembling plate units to form a micro-sieve structure, the particle size of the micro-sieve structure can be easily controlled and the overall screening accuracy can be improved. In addition, the modular plate unit is easy to mass-produce, and the plate unit itself is also easy to assemble and disassemble, so it has the advantage of easy cleaning and maintenance.

請參照圖1,其係繪示依照本揭露之一實施方式的一種切向流過濾組件的裝置示意圖。本實施方式之切向流過濾組件10主要包含外管20以及切向流過濾模組30。外管20具有第一端21、第二端22以及容置空間23。其中,第一端21相對第二端22,容置空間23為外管20之內部空間。切向流過濾模組30設置在外管20的容置空間23中,且外管20主要是用來承接經由切向流過濾模組30過濾出之液體。Please refer to FIG. 1 , which is a schematic diagram of an apparatus of a tangential flow filter element according to an embodiment of the present disclosure. The tangential flow filter assembly 10 of this embodiment mainly includes an outer tube 20 and a tangential flow filter module 30 . The outer tube 20 has a first end 21 , a second end 22 and an accommodating space 23 . The first end 21 is opposite to the second end 22 , and the accommodating space 23 is the inner space of the outer tube 20 . The tangential flow filter module 30 is disposed in the accommodating space 23 of the outer tube 20 , and the outer tube 20 is mainly used for receiving the liquid filtered by the tangential flow filter module 30 .

請一併參照圖2及圖3,其中圖2係繪示依照本揭露之一實施方式的一種板片單元之結構示意圖,圖3係繪示依照本揭露之一實施方式的一種板片單元之側面示意圖。本實施方式之切向流過濾模組30包含依序串接之複數個板片單元31。其中,每一個板片單元31包含本體311、第一接合部312、第二接合部313、第一凸緣314及第二凸緣315。其中,本體311具有第一側面311a、第二側面311b以及穿孔311c,第一側面311a相對第二側面311b,且穿孔311c從第一側面311a貫穿至第二側面311b。Please refer to FIG. 2 and FIG. 3 together, wherein FIG. 2 is a schematic structural diagram of a plate unit according to an embodiment of the present disclosure, and FIG. 3 is a schematic diagram of a plate unit according to an embodiment of the present disclosure. Side view. The tangential flow filter module 30 of this embodiment includes a plurality of plate units 31 connected in series. Wherein, each plate unit 31 includes a body 311 , a first engaging portion 312 , a second engaging portion 313 , a first flange 314 and a second flange 315 . The body 311 has a first side 311a, a second side 311b and a through hole 311c, the first side 311a is opposite to the second side 311b, and the through hole 311c penetrates from the first side 311a to the second side 311b.

如圖2及圖3所示,第一接合部312凸設於第一側面311a。具體而言,第一接合部312是從第一側面311a的四個角落凸出之凸塊。第一凸緣314凸伸於第一側面311a,且環繞穿孔311c。同樣地,第二接合部313凸設於第二側面311b。具體而言,第二接合部313是從第二側面311b的四個角落凸出之凸塊。第二凸緣315凸伸於第二側面311b,且環繞穿孔311c。在一實施例中,第一凸緣314的凸伸高度略低於第一接合部312的凸伸高度,且第一凸緣314與第一接合部312之間具有第一高度差H1。同樣地,第二接合部313的凸伸高度略低於第二凸緣315的凸伸高度,且第二接合部313與第二凸緣315之間具有第二高度差H2。藉此,當數個板片單元31串接在一起時,如圖3及圖5所示,任一板片單元31的第一接合部312與相鄰之板片單元31的第二接合部313互相抵接,使任一板片單元31的第一凸緣314與相鄰之板片單元31的第二凸緣315共同形成微篩結構A1,且此微篩結構A1的開口寬度是由第一高度差H1與相鄰之板片單元之第二高度差H2所結合形成的開口寬度。As shown in FIG. 2 and FIG. 3 , the first engaging portion 312 is protruded from the first side surface 311 a. Specifically, the first engaging portion 312 is a protrusion protruding from the four corners of the first side surface 311a. The first flange 314 protrudes from the first side surface 311a and surrounds the through hole 311c. Similarly, the second engaging portion 313 is protruded from the second side surface 311b. Specifically, the second engaging portion 313 is a protrusion protruding from the four corners of the second side surface 311b. The second flange 315 protrudes from the second side surface 311b and surrounds the through hole 311c. In one embodiment, the protruding height of the first flange 314 is slightly lower than the protruding height of the first engaging portion 312 , and there is a first height difference H1 between the first flange 314 and the first engaging portion 312 . Similarly, the protruding height of the second engaging portion 313 is slightly lower than the protruding height of the second flange 315 , and there is a second height difference H2 between the second engaging portion 313 and the second flange 315 . Thereby, when several plate units 31 are connected in series, as shown in FIG. 3 and FIG. 5 , the first joint 312 of any plate unit 31 and the second joint of the adjacent plate unit 31 313 abut each other, so that the first flange 314 of any plate unit 31 and the second flange 315 of the adjacent plate unit 31 together form a micro-sieve structure A1, and the opening width of the micro-sieve structure A1 is determined by The width of the opening formed by the combination of the first height difference H1 and the second height difference H2 of the adjacent plate units.

在一些實施例中,板片單元31之間、或板片單元31與第一接頭單元32及第二接頭單元33之間,可透過桿體(圖未示)互相連接,且透過改變板片單元31之間的抵緊程度,可微調微篩結構A1之開口寬度,以達到精確控制欲篩選的微球尺寸的目的。在一實施例中,改變板片單元31之間的抵緊程度可透過板片單元31本身的材料些微形變來實現。或者,在另一例子中,亦可於二相鄰板片單元31之本體311之間設置一彈性元件(圖未示)來達到改變板片單元31之間的抵緊程度之目的。具體而言,彈性元件之一端連接於二相鄰板片單元中一者之第一結合部312,彈性元件之另一端連接於二相鄰板片單元中另一者之第二結合部,透過彈性元件的壓縮或拉伸,可調整兩相鄰板片單元31之間距,以達到調整微篩結構A1之開口寬度之目的。在一些具體實施例中,彈性元件可包含彈簧、橡膠或彈性片,且不以此些為限。In some embodiments, the plate units 31, or between the plate units 31 and the first joint unit 32 and the second joint unit 33, can be connected to each other through a rod body (not shown), and by changing the plates The tightness between the units 31 can fine-tune the opening width of the micro-sieve structure A1, so as to precisely control the size of the microspheres to be screened. In one embodiment, changing the degree of contact between the plate units 31 can be achieved by slightly deforming the material of the plate units 31 themselves. Or, in another example, an elastic element (not shown) can also be arranged between the bodies 311 of two adjacent plate units 31 to achieve the purpose of changing the degree of pressing between the plate units 31 . Specifically, one end of the elastic element is connected to the first joint 312 of one of the two adjacent plate units, and the other end of the elastic element is connected to the second joint of the other of the two adjacent plate units. The compression or tension of the elastic element can adjust the distance between two adjacent plate units 31, so as to achieve the purpose of adjusting the opening width of the micro-sieve structure A1. In some specific embodiments, the elastic element may include a spring, a rubber or an elastic sheet, but not limited thereto.

在一實施例中,如圖2及圖5所示,為使微篩結構A1之開口寬度的調整過程能夠穩定,每一板片單元31設置有一貫穿本體311使第一結合部312與第二結合部313連通之穿孔T1。透過桿體穿過每一板片單元31之穿孔T1,可達到串接各板片單元31之目的。在其他實施例中,前述之彈性元件可套設於桿體上,以避免彈性元件鬆脫。在一些實施例中,桿體更包含螺紋,螺紋可為連續螺紋或不連續螺紋,其中連續螺紋意指其多個螺紋部相互連接,透過二螺帽螺合於該連續螺紋之起始端與結尾端,可透過移動位於連續螺紋之起始端與結尾端之板片單元31來以一次性調整所有微篩結構A1之寬度;不連續螺紋意指其多個螺紋部未相互連接,透過二螺帽螺合於不連續螺紋,可透過移動位於二螺帽之間的板片單元31來調整二螺帽之間所有微篩結構A1之寬度。在一具體例子中,桿體可為螺絲等鎖固件。In one embodiment, as shown in FIG. 2 and FIG. 5 , in order to stabilize the adjustment process of the opening width of the micro-sieve structure A1, each plate unit 31 is provided with a through body 311 so that the first joint 312 and the second The connecting portion 313 communicates with the through hole T1. Through the rod body passing through the through hole T1 of each plate unit 31 , the purpose of connecting the plate units 31 in series can be achieved. In other embodiments, the aforementioned elastic element can be sleeved on the rod body to prevent the elastic element from loosening. In some embodiments, the rod body further includes a thread, and the thread can be a continuous thread or a discontinuous thread, wherein the continuous thread means that a plurality of threaded portions thereof are connected to each other, and are screwed to the starting end and the end of the continuous thread through two nuts The width of all the micro-sieve structures A1 can be adjusted at one time by moving the plate units 31 located at the start and end ends of the continuous thread; the discontinuous thread means that its multiple thread parts are not connected to each other, through the two nuts Screwed to the discontinuous thread, the width of all the micro-sieve structures A1 between the two nuts can be adjusted by moving the plate unit 31 between the two nuts. In a specific example, the rod body can be a fastener such as a screw.

請繼續參照圖2、圖3及圖5,在一實施例中,第一凸緣314具有第一外表面,第一外表面可為一斜面,且從第一側面311a往穿孔311c之中心軸S1的方向延伸至第一凸緣314的頂端。第二凸緣315具有第二外表面,第二外表面可為斜面,且從第二側面311b往穿孔311c之中心軸S1的方向延伸至第二凸緣315的頂端。具體而言,分別環繞穿孔311c之第一凸緣314與第二凸緣315分別形成火山口形狀之設計。藉此,當數個板片單元31串接在一起時,如圖3所示,任一板片單元31的第一凸緣314之第一外表面與相鄰之板片單元31的第二凸緣315之第二外表面可共同形成寬度漸變之微篩結構A1。具體而言,微篩結構A1的寬度是從靠近穿孔311c的一端往遠離穿孔311c之另一端變大(如圖5所示)。藉此,當數個板片單元31串接在一起時,這些板片單元31之穿孔311c會形成流道,且當待過濾液體沿著板片單元31的排列方向流動而通過這些穿孔311c時,待過濾液體中的小於微篩結構A1之開口寬度的微球將會沿著垂直於板片單元31的排列方向的方向通過微篩結構A1,而達到過濾特定尺寸微球之目的。微篩結構A1的寬度漸變的設計,除了減小微球通過摩擦力外,亦可在流體中產生壓力差以增加微球通過的速率。Please continue to refer to FIG. 2 , FIG. 3 and FIG. 5 , in one embodiment, the first flange 314 has a first outer surface, the first outer surface may be an inclined surface, and the center axis from the first side surface 311 a to the through hole 311 c The direction of S1 extends to the top end of the first flange 314 . The second flange 315 has a second outer surface, the second outer surface may be an inclined surface, and extends from the second side surface 311b toward the center axis S1 of the through hole 311c to the top of the second flange 315 . Specifically, the first flange 314 and the second flange 315 surrounding the through hole 311c respectively form a design in the shape of a crater. Therefore, when several plate units 31 are connected in series, as shown in FIG. 3 , the first outer surface of the first flange 314 of any plate unit 31 is The second outer surfaces of the flanges 315 may collectively form a micro-sieve structure A1 with a gradual width. Specifically, the width of the micro-sieve structure A1 increases from one end close to the through hole 311c to the other end away from the through hole 311c (as shown in FIG. 5 ). Thereby, when several plate units 31 are connected in series, the through holes 311c of these plate units 31 will form flow channels, and when the liquid to be filtered flows along the arrangement direction of the plate units 31 and passes through these through holes 311c , the microspheres in the liquid to be filtered that are smaller than the opening width of the microsieve structure A1 will pass through the microsieve structure A1 along the direction perpendicular to the arrangement direction of the plate units 31 to achieve the purpose of filtering microspheres of a specific size. The width-gradient design of the microsieve structure A1 not only reduces the frictional force of the microspheres passing through, but also generates a pressure difference in the fluid to increase the speed of the microspheres passing through.

請同時參照圖1及圖4,其中圖4係繪示依照本揭露之一實施方式的一種第一接頭單元之結構示意圖。在一實施例中,切向流過濾模組30包含第一接頭單元32及第二接頭單元33。其中,第一接頭單元32組接於依序串接之板片單元31中之第一個板片單元31上,且第二接頭單元33組接於依序串接之板片單元31中之最後一個板片單元31上。如圖4所示,第一接頭單元32包含裝配塊本體321、管部322、接合部323及凸緣324。裝配塊本體321具有外側面321a、裝配面321b以及通孔321c。其中外側面321a相對於裝配面321b,且通孔321c從外側面321a貫穿至裝配面321b。管部322設置在外側面321a上,且連通於通孔321c。接合部323凸設於裝配面321b上。具體而言,接合部323是從裝配面321b的四個角落凸出之凸塊。凸緣324凸伸於裝配面321b,且環繞通孔321c。在一實施例中,接合部323凸伸於裝配面321b之高度略高於凸緣324的凸伸高度。欲陳明者,第二接頭單元33的結構與第一接頭單元32的結構實質相同,故於此不再贅述。Please refer to FIG. 1 and FIG. 4 at the same time, wherein FIG. 4 is a schematic structural diagram of a first connector unit according to an embodiment of the present disclosure. In one embodiment, the tangential flow filter module 30 includes a first joint unit 32 and a second joint unit 33 . The first connector unit 32 is assembled on the first board unit 31 of the serially connected board units 31 , and the second connector unit 33 is assembled on the first board unit 31 of the serially connected board units 31 . on the last plate unit 31. As shown in FIG. 4 , the first joint unit 32 includes an assembly block body 321 , a pipe portion 322 , a joint portion 323 and a flange 324 . The assembly block body 321 has an outer side surface 321a, an assembly surface 321b and a through hole 321c. The outer side surface 321a is opposite to the mounting surface 321b, and the through hole 321c penetrates from the outer side surface 321a to the mounting surface 321b. The pipe portion 322 is provided on the outer side surface 321a, and communicates with the through hole 321c. The engaging portion 323 protrudes from the mounting surface 321b. Specifically, the engaging portions 323 are protrusions protruding from the four corners of the mounting surface 321b. The flange 324 protrudes from the mounting surface 321b and surrounds the through hole 321c. In one embodiment, the height of the engaging portion 323 protruding from the mounting surface 321b is slightly higher than the protruding height of the flange 324 . To illustrate, the structure of the second connector unit 33 is substantially the same as that of the first connector unit 32 , and thus will not be repeated here.

如圖1、圖3及圖4所示,當第一接頭單元32組接於第一個板片單元31時,第一接頭單元32的接合部323是與第一個板片單元31之第二接合部313互相抵接,使第一接頭單元32的凸緣324與第一個板片單元31的第二凸緣315共同形成微篩結構。同樣地,當第二接頭單元33組接於最後一個板片單元31時,第二接頭單元33的接合部323是與最後一個板片單元31的第一接合部312互相抵接,使第二接頭單元33的凸緣324與最後一個板片單元31的第一凸緣314共同形成微篩結構。As shown in FIG. 1 , FIG. 3 and FIG. 4 , when the first joint unit 32 is assembled with the first plate unit 31 , the joint portion 323 of the first joint unit 32 is the first joint with the first plate unit 31 . The two joint portions 313 are in contact with each other, so that the flange 324 of the first joint unit 32 and the second flange 315 of the first plate unit 31 together form a micro-sieve structure. Similarly, when the second joint unit 33 is assembled with the last plate unit 31, the joint part 323 of the second joint unit 33 is in contact with the first joint part 312 of the last plate unit 31, so that the second joint part 323 The flange 324 of the joint unit 33 and the first flange 314 of the last plate unit 31 together form a micro-sieve structure.

請同時參照圖1及圖5,圖5係繪示依照本揭露之第一實施方式的一種切向流過濾模組的剖面示意圖。在一實施例中,當切向流過濾模組30設置在外管20的容置空間23中時,第一接頭單元32的管部322延伸在外管20的第一端21外,第二接頭單元33的管部322延伸在外管20的第二端22外。藉此,當待過濾液體可從第一接頭單元32的管部322流經板片單元31的穿孔311c,而往第二接頭單元33的管部322流動時,待過濾液體中的小於微篩結構A1尺寸的微球將通過微篩結構A1進入容置空間23中,達到篩選待過濾液體中微球之目的。Please refer to FIG. 1 and FIG. 5 at the same time. FIG. 5 is a schematic cross-sectional view of a tangential flow filter module according to the first embodiment of the present disclosure. In one embodiment, when the tangential flow filter module 30 is disposed in the accommodating space 23 of the outer pipe 20, the pipe portion 322 of the first joint unit 32 extends outside the first end 21 of the outer pipe 20, and the second joint unit Tube portion 322 of 33 extends beyond second end 22 of outer tube 20 . Thereby, when the liquid to be filtered can flow from the pipe portion 322 of the first joint unit 32 through the perforations 311c of the plate unit 31 to the pipe portion 322 of the second joint unit 33, the liquid to be filtered is smaller than the microsieve. The microspheres of the size of the structure A1 will enter the accommodating space 23 through the microsieve structure A1 to achieve the purpose of screening the microspheres in the liquid to be filtered.

在一些實施例中,可在每一片板片單元31的表面鍍上疏水性膜或光滑膜,藉以增加流體及微球之流動性。In some embodiments, a hydrophobic film or a smooth film may be plated on the surface of each plate unit 31 to increase the fluidity of the fluid and the microspheres.

由上述本發明實施方式可知,本發明主要是將模組化的板片單元堆疊形成待過濾液體流道以及微篩結構,透過搭配管線配置與加壓幫浦可達到循環式的微球篩選之目的。另一方面,利用堆疊組裝板片單元形成微篩結構的方式,可方便控制微篩結構的微粒篩選尺寸,提升整體的篩選精度。此外,模組化的板片單元除了容易量產外,板片單元本身也容易組裝與拆卸,故具有容易清洗保養之優點。As can be seen from the above-mentioned embodiments of the present invention, the present invention mainly stacks modular plate units to form a liquid flow channel to be filtered and a micro-sieve structure, and a cyclic micro-sphere screening can be achieved by matching the pipeline configuration and the pressurized pump. Purpose. On the other hand, by stacking and assembling plate units to form a micro-sieve structure, the particle size of the micro-sieve structure can be easily controlled and the overall screening accuracy can be improved. In addition, the modular plate unit is easy to mass-produce, and the plate unit itself is also easy to assemble and disassemble, so it has the advantage of easy cleaning and maintenance.

雖然本揭露之實施例已以實施例揭露如上,然其並非用以限定本揭露之實施例,任何所屬技術領域中具有通常知識者,在不脫離本揭露之實施例的精神和範圍內,當可作些許的更動與潤飾,故本揭露之實施例的保護範圍當視後附的申請專利範圍所界定者為準。Although the embodiments of the present disclosure have been disclosed above with examples, they are not intended to limit the embodiments of the present disclosure. Anyone with ordinary knowledge in the technical field, without departing from the spirit and scope of the embodiments of the present disclosure, should Slight changes and modifications may be made, so the protection scope of the embodiments of the present disclosure should be determined by the scope of the appended patent application.

10:切向流過濾組件 20:外管 21:第一端 22:第二端 23:容置空間 30:切向流過濾模組 31:板片單元 311:本體 311a:第一側面 311b:第二側面 311c:穿孔 312:第一接合部 313:第二接合部 314:第一凸緣 315:第二凸緣 32:第一接頭單元 321:裝配塊本體 321a:外側面 321b:裝配面 321c:通孔 322:管部 323:接合部 324:凸緣 33:第二接頭單元 A1:微篩結構 S1:中心軸 H1: 第一高度差 H2: 第二高度差 T1:穿孔 10: Tangential flow filter assembly 20: Outer tube 21: First End 22: Second End 23: Accommodating space 30: Tangential flow filter module 31: Plate unit 311: Ontology 311a: first side 311b: second side 311c: Perforated 312: The first joint 313: Second Joint 314: First flange 315: Second flange 32: The first connector unit 321: Assembly block body 321a: outer side 321b: Mounting Surface 321c: Through hole 322: Tube Department 323: Joint 324: Flange 33: Second connector unit A1: Microsieve structure S1: Center axis H1: first height difference H2: Second height difference T1: perforated

為讓本揭露之上述和其他目的、特徵、優點與實施例能更明顯易懂,所附圖式之說明如下: 圖1係繪示依照本揭露之一實施方式的一種切向流過濾組件的裝置示意圖; 圖2係繪示依照本揭露之一實施方式的一種板片單元之結構示意圖; 圖3係繪示依照本揭露之一實施方式的一種板片單元之側面示意圖; 圖4係繪示依照本揭露之一實施方式的一種第一接頭單元之結構示意圖; 圖5係繪示依照本揭露之第一實施方式的一種切向流過濾模組的剖面示意圖。 In order to make the above and other objects, features, advantages and embodiments of the present disclosure more clearly understood, the accompanying drawings are described as follows: FIG. 1 is a schematic diagram illustrating a device of a tangential flow filter assembly according to an embodiment of the present disclosure; FIG. 2 is a schematic structural diagram of a plate unit according to an embodiment of the present disclosure; 3 is a schematic side view of a plate unit according to an embodiment of the present disclosure; 4 is a schematic structural diagram of a first connector unit according to an embodiment of the present disclosure; 5 is a schematic cross-sectional view of a tangential flow filter module according to the first embodiment of the present disclosure.

國內寄存資訊(請依寄存機構、日期、號碼順序註記) 無 國外寄存資訊(請依寄存國家、機構、日期、號碼順序註記) 無 Domestic storage information (please note in the order of storage institution, date and number) none Foreign deposit information (please note in the order of deposit country, institution, date and number) none

10:切向流過濾組件 20:外管 21:第一端 22:第二端 23:容置空間 30:切向流過濾模組 31:板片單元 32:第一接頭單元 321c:通孔 322:管部 33:第二接頭單元 10: Tangential flow filter assembly 20: Outer tube 21: First End 22: Second End 23: Accommodating space 30: Tangential flow filter module 31: Plate unit 32: The first connector unit 321c: Through hole 322: Tube Department 33: Second connector unit

Claims (10)

一種切向流過濾模組,包含依序串接之複數個板片單元,其中每一該些板片單元包含:一本體,具有一第一側面、一第二側面以及一穿孔,其中該第一側面相對該第二側面,且該穿孔從該第一側面貫穿至該第二側面;一第一接合部與一第二接合部,分別凸設於該第一側面與該第二側面;一第一凸緣與一第二凸緣,分別凸伸於該第一側面與該第二側面,且環繞該穿孔;以及一第一接頭單元與一第二接頭單元,其中該第一接頭單元與該第二接頭單元分別包含:一裝配塊本體,具有一外側面、一裝配面以及一通孔,其中該外側面相對該裝配面,且該通孔從該外側面貫穿至該裝配面;一管部,設置在該外側面上,且連通該通孔;以及一接合部,凸設於該裝配面上;其中,任一該板片單元的該第一接合部與相鄰之該板片單元的該第二接合部互相抵接,使任一該板片單元的該第一凸緣與相鄰之該板片單元的該第二凸緣共同形成一微篩結構;其中,該第一接頭單元組接於該些板片單元中之第一個該板片單元之該第二接合部,且該第二接頭單元組接於該 些板片單元中之最後一個該板片單元之該第一接合部。 A tangential flow filter module, comprising a plurality of plate units serially connected in series, wherein each of the plate units includes: a body having a first side surface, a second side surface and a perforation, wherein the first side surface A side surface is opposite to the second side surface, and the through hole penetrates from the first side surface to the second side surface; a first joint portion and a second joint portion are respectively protruded from the first side surface and the second side surface; a A first flange and a second flange respectively protrude from the first side surface and the second side surface and surround the through hole; and a first joint unit and a second joint unit, wherein the first joint unit and the The second joint units respectively include: an assembly block body having an outer side surface, an assembly surface and a through hole, wherein the outer side surface is opposite to the assembly surface, and the through hole penetrates from the outer side surface to the assembly surface; a pipe a joint part, which is arranged on the outer surface and communicates with the through hole; and a joint part, which is protruded on the assembling surface; wherein, the first joint part of any one of the plate units is connected to the adjacent plate unit The second joint parts of the two abut each other, so that the first flange of any plate unit and the second flange of the adjacent plate unit together form a micro-sieve structure; wherein, the first joint The unit is assembled to the second joint part of the first one of the plate units, and the second connector unit is assembled to the the first joint of the last one of the plate units. 如請求項1所述之切向流過濾模組,其中該第一凸緣具有一第一外表面,該第一外表面是從該第一側面往該穿孔之一中心軸的方向延伸至該第一凸緣之頂端;該第二凸緣具有一第二外表面,該第二外表面是從該第二側面往該穿孔之該中心軸的方向延伸至該第二凸緣之頂端;任一該板片單元的該第一凸緣之該第一外表面與相鄰之該板片單元的該第二凸緣之該第二外表面共同形成寬度漸變之該微篩結構。 The tangential flow filter module as claimed in claim 1, wherein the first flange has a first outer surface, and the first outer surface extends from the first side to the direction of a central axis of the through hole to the The top end of the first flange; the second flange has a second outer surface, and the second outer surface extends from the second side to the top of the second flange in the direction of the center axis of the through hole; any The first outer surface of the first flange of the plate unit and the second outer surface of the second flange of the adjacent plate unit together form the micro-sieve structure with a gradual width. 如請求項1所述之切向流過濾模組,其中該第一接合部與該第一凸緣之間具有一第一高度差;該第二接合部與該第二凸緣之間具有一第二高度差;其中,該第一高度差與該第二高度差共同形成該微篩結構之一開口寬度。 The tangential flow filter module of claim 1, wherein there is a first height difference between the first joint portion and the first flange; and a first height difference is formed between the second joint portion and the second flange a second height difference; wherein, the first height difference and the second height difference together form an opening width of the micro-sieve structure. 如請求項1所述之切向流過濾模組,其中每一該些板片單元之表面鍍有疏水性膜或光滑膜。 The tangential flow filter module according to claim 1, wherein the surface of each of the plate units is coated with a hydrophobic film or a smooth film. 如請求項1所述之切向流過濾模組,其中該第一接頭單元與該第二接頭單元分別更包含一凸緣, 該凸緣凸伸於該裝配面,且環繞該通孔;該第一接頭單元的該凸緣與該些板片單元中之第一個該板片單元之該第二凸緣共同形成另一微篩結構,該第二接頭單元的該凸緣與該些板片單元中之最後一個該板片單元之該第一凸緣共同形成又一微篩結構。 The tangential flow filter module according to claim 1, wherein the first joint unit and the second joint unit further comprise a flange, respectively, The flange protrudes from the mounting surface and surrounds the through hole; the flange of the first connector unit and the second flange of the first one of the plate units together form another In the micro-sieve structure, the flange of the second joint unit and the first flange of the last plate unit of the plate units together form another micro-sieve structure. 如請求項1所述之切向流過濾模組,更包含一彈性元件,裝設於相鄰之兩板片單元之該些本體間。 The tangential flow filter module according to claim 1 further comprises an elastic element installed between the bodies of the two adjacent plate units. 一種切向流過濾組件,包含:一如請求項1所述之切向流過濾模組;以及一外管,具有一第一端、相對該第一端之一第二端、以及一容置空間,其中該切向流過濾模組設置在該容置空間中,且該第一接頭單元的該管部延伸在該第一端外,該第二接頭單元的該管部延伸在該第二端外;其中,當待過濾液體從該第一接頭單元的該管部流經該些板片單元的該些穿孔,而往該第二接頭單元的該管部流動時,待過濾液體中的小於該些微篩結構尺寸的微球將通過該些微篩結構進入該容置空間中。 A tangential flow filter assembly, comprising: a tangential flow filter module as described in claim 1; and an outer tube having a first end, a second end opposite to the first end, and an accommodating space, wherein the tangential flow filter module is arranged in the accommodating space, and the pipe portion of the first joint unit extends outside the first end, and the pipe portion of the second joint unit extends beyond the second joint unit Wherein, when the liquid to be filtered flows from the pipe part of the first joint unit through the perforations of the plate units and flows to the pipe part of the second joint unit, the liquid to be filtered in the liquid Microspheres smaller than the size of the micro-sieve structures will enter the accommodating space through the micro-sieve structures. 如請求項7所述之切向流過濾組件,其中每一該些板片單元之該第一凸緣具有一第一外表面,該第一外表面是從該第一側面往該穿孔之一中心軸的方向延伸至該第一凸緣之頂端; 每一該些板片單元之該第二凸緣具有一第二外表面,該第二外表面是從該第二側面往該穿孔之該中心軸的方向延伸至該第二凸緣之頂端;以及任一該板片單元的該第一凸緣之該第一外表面與相鄰之該板片單元的該第二凸緣之該第二外表面共同形成寬度漸變之該微篩結構。 The tangential flow filter assembly of claim 7, wherein the first flange of each of the plate units has a first outer surface, the first outer surface extending from the first side to one of the through holes The direction of the central axis extends to the top of the first flange; The second flange of each of the plate units has a second outer surface, and the second outer surface extends from the second side to the top of the second flange in the direction of the central axis of the through hole; and the first outer surface of the first flange of any one of the plate units and the second outer surface of the second flange of the adjacent plate unit together form the micro-sieve structure with a gradual width. 如請求項7所述之切向流過濾組件,其中每一該些板片單元之該第一接合部與該第一凸緣之間具有一第一高度差;每一該些板片單元之該第二接合部與該第二凸緣之間具有一第二高度差;其中,該第一高度差與該第二高度差共同形成該微篩結構之一開口寬度。 The tangential flow filter assembly of claim 7, wherein there is a first height difference between the first joint and the first flange of each of the plate units; There is a second height difference between the second joint portion and the second flange; wherein, the first height difference and the second height difference together form an opening width of the micro-sieve structure. 如請求項7所述之切向流過濾組件,其中每一該些板片單元之表面鍍有疏水性膜或光滑膜。The tangential flow filter assembly according to claim 7, wherein the surface of each of the plate units is coated with a hydrophobic film or a smooth film.
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004237208A (en) * 2003-02-06 2004-08-26 Corona Industry Co Ltd Filter structure of solid-liquid separator
TWI333427B (en) * 2008-02-19 2010-11-21 Yeu Ming Tai Chemical Ind Co Ltd
WO2018234593A1 (en) * 2017-06-20 2018-12-27 Novhidro, S.L. Modular element for compartmentalised filtration

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004237208A (en) * 2003-02-06 2004-08-26 Corona Industry Co Ltd Filter structure of solid-liquid separator
TWI333427B (en) * 2008-02-19 2010-11-21 Yeu Ming Tai Chemical Ind Co Ltd
WO2018234593A1 (en) * 2017-06-20 2018-12-27 Novhidro, S.L. Modular element for compartmentalised filtration

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