TWI748349B - 腫瘤特異性多肽序列及其應用 - Google Patents

腫瘤特異性多肽序列及其應用 Download PDF

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Publication number
TWI748349B
TWI748349B TW109105388A TW109105388A TWI748349B TW I748349 B TWI748349 B TW I748349B TW 109105388 A TW109105388 A TW 109105388A TW 109105388 A TW109105388 A TW 109105388A TW I748349 B TWI748349 B TW I748349B
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Taiwan
Prior art keywords
seq
polypeptide
tumor
peptide
cells
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TW109105388A
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English (en)
Chinese (zh)
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TW202118772A (zh
Inventor
邱思
李波
李佑平
張樂
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大陸商武漢華大吉諾因生物科技有限公司
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
TW109105388A 2019-11-07 2020-02-20 腫瘤特異性多肽序列及其應用 TWI748349B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/CN2019/116164 WO2021087839A1 (fr) 2019-11-07 2019-11-07 Séquence polypeptidique spécifique d'une tumeur et application associée
CNPCT/CN2019/116164 2019-11-07

Publications (2)

Publication Number Publication Date
TW202118772A TW202118772A (zh) 2021-05-16
TWI748349B true TWI748349B (zh) 2021-12-01

Family

ID=75849465

Family Applications (1)

Application Number Title Priority Date Filing Date
TW109105388A TWI748349B (zh) 2019-11-07 2020-02-20 腫瘤特異性多肽序列及其應用

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CN (1) CN114651002A (fr)
TW (1) TWI748349B (fr)
WO (1) WO2021087839A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117316273B (zh) * 2023-11-02 2024-09-06 聊城市人民医院 基于图神经网络的肿瘤个体化新抗原多肽筛选方法及装置

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201930340A (zh) * 2017-12-18 2019-08-01 美商尼恩醫療公司 新抗原及其用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8828957B2 (en) * 2003-12-11 2014-09-09 Microvax, Llc Methods for generating immunity to antigen
ATE439383T1 (de) * 2005-09-20 2009-08-15 Peter Jon Nelson Gewebeinhibitor für metalloproteinasen (timp) gebunden an ein glycosylphosphatidylinositol (gpi-) anker zur behandlung von krebs
DE602005015733D1 (de) * 2005-12-02 2009-09-10 Apceth Gmbh & Co Kg Chemokin-Mucin Fusionsproteine mit einer GPI-Ankerdomäne und deren Verwendung als Tumor-Immun-Adjuvanzien oder in der Geweberegeneration
WO2014193999A2 (fr) * 2013-05-28 2014-12-04 Caris Science, Inc. Méthodes et compositions d'identification de biomarqueurs
DK3288581T3 (da) * 2015-04-27 2021-01-11 Cancer Research Tech Ltd Fremgangsmåde til behandling af cancer
US11548925B2 (en) * 2016-09-30 2023-01-10 Genoimmune Therapeutics Co., Ltd. CACNA1H-derived tumor antigen polypeptide and use thereof
CN110272874A (zh) * 2018-03-15 2019-09-24 北京卡替医疗技术有限公司 一种包含负载新抗原的b细胞疫苗的免疫细胞药物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201930340A (zh) * 2017-12-18 2019-08-01 美商尼恩醫療公司 新抗原及其用途

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Liang, Zhaoduan, et al., "The common neoantigens in colorectal cancer are predicted and validated to be presented or immunogenic",bioRxiv, June, 2019, page 1-38. *

Also Published As

Publication number Publication date
CN114651002A (zh) 2022-06-21
TW202118772A (zh) 2021-05-16
WO2021087839A1 (fr) 2021-05-14

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