TWI722035B - Ｃｇｒｐ受體拮抗劑 - Google Patents
Ｃｇｒｐ受體拮抗劑 Download PDFInfo
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- TWI722035B TWI722035B TW105135022A TW105135022A TWI722035B TW I722035 B TWI722035 B TW I722035B TW 105135022 A TW105135022 A TW 105135022A TW 105135022 A TW105135022 A TW 105135022A TW I722035 B TWI722035 B TW I722035B
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- compound
- oxo
- pyridin
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
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Landscapes
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| WO2018178938A1 (en) * | 2017-03-31 | 2018-10-04 | Heptares Therapeutics Limited | Cgrp receptor antagonists |
| DK4088720T3 (da) * | 2018-03-25 | 2025-09-29 | Pfizer Ireland Pharmaceuticals Unlimited Company | Rimegepant til cgrp-relaterede lidelser |
| US20210361774A1 (en) | 2018-10-16 | 2021-11-25 | Dana-Farber Cancer Institute, Inc. | Degraders of wild-type and mutant forms of lrrk2 |
| AU2019371400B2 (en) | 2018-11-02 | 2024-10-17 | Dana-Farber Cancer Institute, Inc. | Acetylation writer inhibitor development and uses thereof |
| GB201908420D0 (en) * | 2019-06-12 | 2019-07-24 | Heptares Therapeutics Ltd | Cgrp antagonist compounds |
| GB201908430D0 (en) | 2019-06-12 | 2019-07-24 | Heptares Therapeutics Ltd | Cgrp antagonist compounds |
| WO2021141662A1 (en) | 2020-01-10 | 2021-07-15 | Massachusetts Institute Of Technology | Proteolysis targeting chimeric molecules (protacs) with functional handles and uses thereof |
| CN115697378A (zh) * | 2020-03-23 | 2023-02-03 | 拜尔哈文制药股份有限公司 | 用cgrp抑制剂治疗肺部损伤的方法 |
| WO2022183006A1 (en) | 2021-02-25 | 2022-09-01 | Mayo Foundation For Medical Education And Research | Compounds for programmable protein degradation and methods of use for the disease treatment |
| WO2023034466A1 (en) * | 2021-09-02 | 2023-03-09 | Pfizer Ireland Pharmaceuticals | Cgrp antagonists for treating psoriasis |
| CN116023391B (zh) * | 2022-12-13 | 2024-09-06 | 药康众拓(江苏)医药科技有限公司 | 一类氘代哌啶酰胺类cgrp抑制剂药物及用途 |
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| WO2004037811A1 (de) * | 2002-10-25 | 2004-05-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ausgewählte cgrp-antagonisten, verfahren zu deren herstellung sowie deren verwendung als arzneimittel |
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| US20180015085A1 (en) | 2018-01-18 |
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| BR112018008423A2 (pt) | 2018-11-06 |
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| AR106486A1 (es) | 2018-01-17 |
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| US20210213011A1 (en) | 2021-07-15 |
| IL258892A (en) | 2018-06-28 |
| CN108473465A (zh) | 2018-08-31 |
| US10888561B2 (en) | 2021-01-12 |
| US9808457B2 (en) | 2017-11-07 |
| AU2016347521A1 (en) | 2018-05-17 |
| US10300056B2 (en) | 2019-05-28 |
| US12178813B2 (en) | 2024-12-31 |
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| CN108473465B (zh) | 2021-03-02 |
| EP3368525A1 (en) | 2018-09-05 |
| US20170121348A1 (en) | 2017-05-04 |
| GB201519196D0 (en) | 2015-12-16 |
| BR112018008423B1 (pt) | 2024-02-15 |
| CA3002621A1 (en) | 2017-05-04 |
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