TWI720075B - 使用微核醣核酸前驅物作爲誘導ｃｄ３４陽性成體幹細胞增殖之藥物 - Google Patents
使用微核醣核酸前驅物作爲誘導ｃｄ３４陽性成體幹細胞增殖之藥物 Download PDFInfo
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| US201562262280P | 2015-12-02 | 2015-12-02 | |
| US62/262,280 | 2015-12-02 | ||
| US15/048,964 US10519440B2 (en) | 2012-08-10 | 2016-02-19 | Composition and method of using miR-302 precursors as drugs for treating Alzheimer's diseases |
| US15/048,964 | 2016-02-19 | ||
| US15/167,226 | 2016-05-27 | ||
| US15/167,226 US9879263B2 (en) | 2011-08-12 | 2016-05-27 | Use of microRNA precursors as drugs for inducing CD34-positive adult stem cell expansion |
| WOPCT/US16/49583 | 2016-08-31 | ||
| PCT/US2016/049583 WO2017095489A1 (en) | 2015-12-02 | 2016-08-31 | Use of microrna precursors as drugs for inducing cd34-positive adult stem cell expansion |
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| TW201735932A TW201735932A (zh) | 2017-10-16 |
| TWI720075B true TWI720075B (zh) | 2021-03-01 |
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| US11624067B2 (en) | 2008-05-07 | 2023-04-11 | Shi-Lung Lin | In-vitro induction of adult stem cell expansion and derivation |
| EP3818158B1 (en) * | 2018-07-02 | 2025-10-08 | Shi-Lung Lin | In-vitro induction of adult stem cell expansion and derivation |
| CN112430596B (zh) * | 2019-08-26 | 2025-10-28 | 中国科学院上海营养与健康研究所 | 一类小rna分子及其类似物在抗衰老中的应用 |
| US20220396778A1 (en) * | 2021-06-12 | 2022-12-15 | Shi-Lung Lin | Novel RNA Composition and Production Method for Use in iPS Cell Generation |
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| TW201321507A (zh) * | 2011-08-12 | 2013-06-01 | Mello Biotechnology Inc | 用於在原核細胞內使用真核第二型聚合酶啟動子驅動之轉錄作用的可誘導之基因表現組成物及其應用 |
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| WO1998046722A1 (en) | 1997-04-16 | 1998-10-22 | Unigene Laboratories Inc. | Direct expression of peptides into culture media |
| US9453219B2 (en) | 2003-05-15 | 2016-09-27 | Mello Biotech Taiwan Co., Ltd. | Cosmetic designs and products using intronic RNA |
| EP1836316A4 (en) | 2004-12-22 | 2009-07-22 | Ambrx Inc | PROCESS FOR EXPRESSION AND CLEANING OF RECOMBINANT HUMAN GROWTH HORMONE |
| WO2009091659A2 (en) * | 2008-01-16 | 2009-07-23 | Shi-Lung Lin | Generation of tumor-free embryonic stem-like pluripotent cells using inducible recombinant rna agents |
| US9879263B2 (en) * | 2011-08-12 | 2018-01-30 | Mello Biotechnology, Inc. | Use of microRNA precursors as drugs for inducing CD34-positive adult stem cell expansion |
| US9422559B2 (en) * | 2010-06-02 | 2016-08-23 | Shi-Lung Lin | Production and utilization of a novel anti-cancer drug in therapy |
| US10196662B2 (en) * | 2012-08-10 | 2019-02-05 | Mello Biotechnology, Inc. | Composition for producing microRNA precursors as drugs for enhancing wound healing and production method of the microRNA precursors |
| CN105143459B (zh) * | 2012-08-10 | 2020-04-14 | 林希龙 | 新颖治疗用抗癌药的制造与使用 |
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| TW201321507A (zh) * | 2011-08-12 | 2013-06-01 | Mello Biotechnology Inc | 用於在原核細胞內使用真核第二型聚合酶啟動子驅動之轉錄作用的可誘導之基因表現組成物及其應用 |
Non-Patent Citations (1)
| Title |
|---|
| Ming Yan.et al. Modulation of Gene Expression by Polymer Nanocapsule Delivery of DNA Cassettes Encoding Small RNAs. PLOS ONE | DOI:10.1371/journal.pone.0127986 June 2, 2015. * |
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| WO2017095489A1 (en) | 2017-06-08 |
| TW201735932A (zh) | 2017-10-16 |
| EP3384026A1 (en) | 2018-10-10 |
| CN108431227A (zh) | 2018-08-21 |
| JP2018535684A (ja) | 2018-12-06 |
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