TWI577792B - Botanic soap formula with an anti-bacterial effect for acne bacteria in vitro - Google Patents

Description

Botanical soap with antibacterial effect against acne bacteria in vitro

The invention relates to a vegetable soap which has antibacterial effect against acne bacteria in vitro, in particular, saponification using a plurality of vegetable oils to form a soap containing no drug and an antibacterial agent, and can effectively inhibit acne bacteria.

According to, acne is the most common skin disease, the incidence of adolescents is as high as 85%, the adult prevalence is 11%, most of the acne occurs in the face, the current treatment of acne is local and systemic antibiotic treatment, and Topical antibiotics can easily cause dry skin, redness, irritation and skin irritation. Oral antibiotics may also cause gastrointestinal dysfunction and increase the risk of venous thromboembolism. Antibiotic treatment is caused worldwide due to rapid bacterial mutation and resistance to acne bacteria. There is a less effective situation.

Therefore, how to solve the long-term problems and shortcomings of the above-mentioned practices is the subject of research and development that the relevant industry is keen to develop.

The main object of the present invention is to use a vegetable soap which does not contain a drug and an antibacterial agent for skin cleansing, to effectively inhibit acne bacteria, to improve pores, to reduce oil secretion, to soothe inflammation, and to have a moisturizing effect.

In order to achieve the above object, the soap of the present invention is formed by saponification of a plurality of vegetable oil mixed alkali liquors, and the vegetable oils are coconut oil, neem oil, borage oil and hazelnut oil in a weight ratio of 21:36:5. The ratio of 36 is configured to allow the user to use the soap of the present invention to continuously clean the skin suffering from acne, thereby effectively inhibiting the acne bacillus, and allowing the oil secretion, soothing inflammation and pores to be significantly improved, and the skin is lifted. Keep humidity.

Further, the coconut oil, neem oil, borage oil and hazelnut oil are organic coconut oil, organic neem oil, organic borage oil and organic hazelnut oil.

The soap of the present invention is produced by the following steps:

1. Preparation of vegetable oil: Cocos nucifera Oil, Azadirachta indica Oil, Borago Officinalis Oil and Corylus avellana Oil in a weight ratio of 21:36 : 5:36 ratio is mixed and heated to a specific temperature of 45 degrees Celsius by water heating and stirred until completely mixed to form a merlot.

2. Prepare lye: According to the weight and saponification price of coconut oil, neem oil, borage oil and hazelnut oil, prepare appropriate weight of sodium hydroxide (NaOH), mix the sodium hydroxide with distilled water and cool to a specific temperature. A lye is formed at 45 degrees Celsius.

3. Mixing: Slowly add the lye to the vegetable oil, stir and mix until it is thick, and pour into the model and place it in the styrofoam box, and maintain a stable temperature to 58 degrees Celsius. The saponification of the lye and vegetable oil is completed. To form soap, the time required for curing is preferably 48 hours.

As mentioned above, in the process of soap drying, the soap must be in a constant temperature and constant humidity condition, and the soap will have a weight decrease with time, and the soap is evaporated and almost matured in the 10th week.

Since the coconut oil used in the present invention contains lauric acid, it can increase the hardness, detergency and foaming property of the soap, and is easily soluble in water, while the neem oil contains oleic acid, which can exert a moisturizing effect, and the neem oil has Nimbidin active ingredient, effective for the treatment of skin diseases, such as: eczema, acne, psoriasis, arsenic dermatitis, acne and seborrheic dermatitis, the active ingredient Azadirachtin (C35H44O16) in neem oil contains tetranortriterpenoid (limonoid) function similar to steroids And the role of steroids is anti-inflammatory; and other chemicals in neem oil can produce synergistic effects such as Nimbin can antipyretic and anti-inflammatory; Nimbidol can also antipyretic; Nimbidin has antibacterial function; Quercentin is a very good anti-inflammatory substance Sulfur compounds such as nimbidin, nimbosterol can eliminate the acne bacteria in the deepest pores of the skin and effectively reduce the swelling of the skin and acne skin. The sulfur compounds can remove excess oil and dissolve the angle plug on the skin surface, and have anti-inflammatory effect; The linoleic acid and hazelnut oil in oleagin oil contain oleic acid, in addition to moisturizing effect It can also reduce the inflammation of the skin. Therefore, the soap prepared by the invention has been proved by experiments to have an effect of improving the skin of the acne, effectively inhibiting the acne bacillus, and allowing the oil secretion, soothing inflammation and pores to be significantly improved and improved. Skin moisturization, and because it does not contain drugs or antibacterial agents, there are no problems such as adverse side effects or drug resistance.

Furthermore, the aforementioned coconut oil, neem oil, borage oil and hazelnut oil can further improve the effect of the present invention by using organic coconut oil, organic neem oil, organic borage oil and organic hazelnut oil. In the present invention, the definition of organic is that no solvent extraction is carried out at room temperature (referred to as Cold Press).

Claims (3)

A vegetable soap having antibacterial activity against Acne Bacillus in vitro, which is Cocos nucifera Oil, Azadirachta indica Oil, Borago Officinalis Oil and Capolis (Corylus avellana) Oil) is formed by saponification of mixed alkali liquor. The weight ratio of coconut oil, neem oil, borage oil and hazelnut oil is 21:36:5:36. A vegetable soap having antibacterial activity against Acne Bacillus in vitro according to claim 1, wherein the coconut oil, neem oil, borage oil and hazelnut oil are organic coconut oil, organic neem oil, organic borage oil With organic hazelnut oil. A vegetable soap having bacteriostatic effect against acne bacteria in vitro according to claim 1, wherein the lye is made of sodium hydroxide (NaOH) mixed distilled water.