TWI555518B - Absorbent items - Google Patents

Description

Absorbent article

The present invention relates to absorbent articles for sanitary napkins, sanitary pads, disposable diapers, incontinence pads, incontinence pads and the like.

In an absorbent article such as a sanitary napkin or a disposable diaper, it is known that embossing is applied to the surface of the top sheet in contact with the skin of the user to form irregularities (Patent Documents 1 to 3). By forming a large number of irregularities by embossing on the skin contact surface of the user, the contact area between the top sheet and the user's skin is reduced.

[Previous Technical Literature]

[Patent Document]

[Patent Document 1] Japanese Patent Laid-Open Publication No. 2008-136563

[Patent Document 2] Japanese Patent Laid-Open Publication No. 2009-512

[Patent Document 3] Japanese Patent Laid-Open Publication No. 2011-15707

However, when the top sheet is embossed to form a large number of irregularities, the embossed portion is compressed and densified, and liquid tends to remain. Therefore, it gives a sticky feeling when used, and gives a visually unpleasant feeling when the product is exchanged after use.

Therefore, the present invention has an object of providing a novel absorbent article having a small contact area between the top sheet and the skin of the user and a small amount of liquid residue on the surface.

In order to solve the above problems, the present invention provides an absorbent article comprising a top sheet, a back sheet, and an absorbent body provided between the top sheet and the back sheet, wherein the top sheet is a liquid supply region for receiving liquid supply. a liquid permeable sheet having an extensible region in which an extensible snake abdomen is formed and a flexible region surrounding the stretchable region, wherein the liquid permeable sheet is stretched once in a second extension of the snake belly, and the aforementioned The stretchable region is provided in such a manner that a raised ridge is formed in the thickness direction of the absorbent article.

The absorbent article of the present invention has the following effects.

The top sheet of the absorbent article of the present invention has a raised portion in the thickness direction of the absorbent article in the liquid supply region, and the contact area with the skin of the user is small. Therefore, the skin touch of the top sheet is improved while preventing stickiness, stuffiness, itching, and the like.

Further, the absorbent article of the present invention is stretched in the liquid supply region, and is stretched once when the liquid is supplied to the supply region side. The snake's abdomen is stretched twice, so that the absorbent body becomes less susceptible to being squeezed by the liquid supply region, preventing excessive compression of the absorbent body due to deformation of the absorbent article and accompanying back bleed.

Further, the absorbent article of the present invention changes the bending angle When the edge is deformed (for example, when the wearer of the absorbent article changes his or her posture, the bending angle of the absorbent article becomes an acute angle or an obtuse angle), the elastic restoring force (rebounding force) of the flexible region is caused by the top sheet. It is easily deformed by deformation of the absorbent article, and prevents the deflection of the top sheet caused by the secondary stretching of the snake abdomen and the adhesion of the deflected sheet to the skin.

According to the present invention, there is provided a novel absorbent article in which the contact area between the top sheet and the skin of the user is small and the body fluid remains on the surface.

1‧‧‧Physical sanitary napkins (absorbent articles)

2‧‧‧Top sheet

3‧‧‧ Back sheet

4‧‧‧Acceptor

20‧‧‧Excretion supply area (liquid supply area)

21‧‧‧Extended area

22‧‧‧Flexible area

200‧‧‧ Uplift

210‧‧‧ snake belly

S‧‧‧liquid permeable sheets

Fig. 1 is a perspective view showing a sanitary napkin according to an embodiment of the present invention.

Fig. 2 is a schematic cross-sectional view showing a section taken along line A-A of Fig. 1.

Fig. 3 is a plan view showing a liquid permeable sheet used as a top sheet in a sanitary napkin according to an embodiment of the present invention.

Fig. 4 is a partial cross-sectional perspective view showing a stretchable region and a flexible region of a liquid permeable sheet used as a top sheet in a sanitary napkin according to an embodiment of the present invention.

Fig. 5 is a perspective view showing a state in which a sanitary napkin is deformed in a convex shape according to an embodiment of the present invention.

Fig. 6 is a view for explaining a method of producing a sanitary napkin according to an embodiment of the present invention.

Fig. 7 is a view for explaining a recess forming roller used for the production of the sanitary napkin according to the embodiment of the present invention.

8] FIG. 8 is a view for explaining a region in which a concave portion is formed by a concave portion forming roller in a top sheet.

Fig. 9 is a view for explaining an upper roll of an extended tooth roll used for the production of the sanitary napkin according to the embodiment of the present invention.

Fig. 10 is a view for explaining a lower roll of an extended tooth roll used for the production of the sanitary napkin according to the embodiment of the present invention.

Fig. 11 is a view for explaining a top sheet extending with an extending tooth roll.

Fig. 12 is an electron micrograph of the skin contact surface of the top sheet in the sanitary napkin of the top sheet containing the three C2L oil fatty acid glycerides.

Fig. 13 is a photomicrograph of menstrual blood with or without a blood modifying agent.

Fig. 14 is a view for explaining a method of measuring surface tension.

[Best Practice for Carrying Out the Invention]

Hereinafter, the absorbent article of the present invention will be described.

In the absorbent article of the present invention, the liquid supply region is preferably set in the top sheet and the liquid permeable sheet serving as the top sheet in accordance with the type and use of the absorbent article, and the position and area of the liquid supply region. Not particularly limited. The liquid supply region may be set to be slightly the same as the liquid supply region or set to be larger than the liquid supply region. However, it is preferable to set the region to be larger than the liquid supply region from the viewpoint of preventing liquid from oozing out to the outside.

In the absorbent article of the present invention, the stretchable region is a snake An area of the abdomen that stretches and stretches. The snake abdomen has a repeating structure of a mountain fold and a valley fold, and can extend in the plane direction of the stretchable region. In addition to stretchability, the snake's abdomen can also have contractility. Further, even when the snake abdomen has contractility, the stretched snake abdomen does not completely contract to the original state due to the material of the snake's abdomen or the number of the snake's abdomen, and maintains a state slightly extended compared with the original state.

In the absorbent article of the present invention, the flexible region is The deformation has an area of elastic restoring force (rebound force). Although the flexible region can be stretched by the force applied during deformation, it is preferable that the elastic restoring force against deformation is substantially not stretched by the force applied during the deformation.

In the absorbent article of the present invention, the flexible region surrounds the stretch All or part of the surrounding area. In the case of convex deformation of the absorbent article, the flexible region surrounds the entire circumference of the stretchable region by 30 to 100 from the viewpoint of effectively generating the secondary stretch of the stretched snake belly and the elastic restoring force of the flexible region. % is better, surrounded by 50~100% better, surrounded by 100% best.

In the absorbent article of the present invention, the liquid permeable sheet is The snake abdomen may be stretched once in a second extension, and the stretchable region is provided in such a manner that a raised ridge is formed in the thickness direction of the absorbent article, and a liquid is supplied to the top sheet to form a bulge in the thickness direction of the absorbent article. Uplift. "Secondary extension" means that the snake's abdomen that has been stretched once is not fully extended and can be further stretched. The first stretch rate is usually 10 to 80% of the maximum stretch of the snake's abdomen. When the convex shape of the absorbent article is deformed, it is preferably 10 to 60% from the viewpoint of effectively generating the stretched belly of the snake belly. ~50% is better.

In the absorbent article of the present invention, the top sheet has a liquid The body-provided region is formed with a plurality of extensible regions of the stretchable snake abdomen and a liquid-permeable sheet surrounding the flexible region of each stretchable region, and the liquid-permeable sheet can be stretched twice with the snake belly of each stretchable region. The stretching is performed once, and each of the stretchable regions is formed so as to form a raised portion in the thickness direction of the absorbent article (Section 1). In the aspect 1, the contact area between the top sheet and the user's skin becomes smaller, the skin contact of the top sheet is increased, and the stickiness, stuffiness, itching, and the like are further prevented.

In the aspect 1, the flexible region is formed into a mesh shape, each It is preferable that the stretched region is formed inside the mesh (Stage 2). In the aspect 2, the snake abdomen is easily stretched once, and the stretchable region is easily swelled in the thickness direction of the absorbent article. Further, in the case of the convex deformation of the absorbent article, the secondary stretching of the snake belly and the elastic restoring force of the flexible region are effectively generated, so that the excessive compression of the absorbent body is effectively prevented, and the snake belly is simultaneously The deflection of the top sheet caused by the secondary stretching and the deflection of the sheet to the muscle The adhesion of the skin is effectively prevented.

In the second aspect, the flexible region has a liquid permeability The first region having a substantially linear shape extending in the direction in which the longitudinal direction of the sheet intersects and being arranged in a slightly parallel manner is preferably a second region which is slightly linear in a direction parallel to the first region and which is arranged in parallel with the first region. Sample 3). In the third aspect, when the absorbent article is convexly deformed, the secondary stretching of the snake belly and the elastic restoring force of the flexible region are effectively generated, so that excessive compression of the absorbent body is effectively prevented, and at the same time The deflection of the top sheet caused by the secondary stretching of the snake's abdomen and the adhesion of the deflected sheet to the skin are effectively prevented.

In the absorbent article of the present invention, the snake abdomen is exposed to liquid The through sheets are extended in the longitudinal direction, and are arranged side by side in the width direction of the liquid permeable sheet, and it is preferable that the cross section in the width direction has a wavy mountain fold portion and a valley fold portion (Section 4). In the aspect 4, when the absorbent article is bent along the longitudinal direction thereof and convexly deformed toward the liquid supply region side, the secondary stretch of the serpent belly which is once stretched toward the width direction of the absorbent article and the elasticity of the flexible region Since the restoring force is effectively generated, the excessive compression of the absorbent body is effectively prevented, and the deflection of the top sheet caused by the secondary stretching of the snake abdomen and the adhesion of the deflected sheet to the skin are effectively prevented.

In the absorbent article of the present invention, the liquid permeable sheet is The manner in which the interior of the ridge is filled with a portion of the absorber is set to be good (Stage 5). In the aspect 5, it is easy to maintain the shape of the ridge portion at the time of pressurization or the shape of the ridge portion after the liquid is transmitted, so that the contact area between the top sheet and the skin of the user is easily maintained at a small value. Also, because it is directly under the liquid permeable sheet The absorber is placed, so that the instantaneous liquid moves to the absorber, and the liquid residue on the surface is further reduced.

In the absorbent article of the present invention, the liquid permeable sheet is The liquid is convexly deformed by the supply region, and one portion of the absorber is compressed by the elastic restoring force of the flexible region due to the convex deformation, compared to the absorber filled in the interior of the ridge In one part, it is preferable that a part of the absorber which is compressed due to the elastic restoring force of the flexible region becomes high density (state 6). In the aspect 6, due to the coarse gradient of the absorber, the liquid that has passed through the ridge is rapidly moved from the portion of the absorber filled in the inside of the ridge to the portion of the absorber that is compressed by the elastic restoring force of the flexible region. In particular, the aspect 6 is preferably combined with the aspect 7. That is, the liquid permeation hole is formed in the stretchable region, the liquid permeation hole is not formed in the flexible region, the liquid permeability of the raised portion is improved, and the absorber is moved to the elastic body which is compressed by the elastic restoring force of the flexible region. Part of the liquid becomes less prone to backflow.

In the absorbent article of the present invention, the stretchable region is formed It is preferable that the liquid permeation hole and the flexible region do not form a liquid permeation hole (Section 7). In the case of the convex deformation of the absorbent article, the flexible region in which the tension is directly applied to the stretchable region where the tension is not directly applied and the tension is directly formed does not form the liquid permeation hole, thereby preventing the liquid from being transmitted through the tension. The holes are stretched and the absorber is exposed.

In the absorbent article of the present invention, in the liquid supply area It is preferred that the peripheral portion of the domain form a compression groove (state 8). The compression groove is formed by integrating the peripheral portion of the liquid supply region with the absorber and then integrating it. Concave. In the aspect 8, the absorbent article is used as a starting point, and the absorbent article is easily deformed convexly. When the absorbent article is convexly deformed, the second stretch of the snake belly and the elastic region of the flexible region are restored. Since the force is effectively generated, the excessive compression of the absorbent body is effectively prevented, and the deflection of the top sheet caused by the secondary stretching of the snake abdomen and the adhesion of the deflected sheet to the skin are effectively prevented.

In the absorbent article of the present invention, the liquid permeable sheet is A blood modifying agent containing a water solubility of 0.000 to 0.60 IOB, a melting point of 45 ° C or less, and a water content of 100 g of water at 25 ° C of 0.00 to 0.05 g is preferable (Section 9). In the aspect 9, when the absorption target of the absorbent article is menstrual blood, the menstrual blood reaching the liquid permeable sheet is modified by contact with the blood modifying agent, and the menstrual blood having high viscosity is less likely to remain in the liquid permeable sheet or the liquid permeable sheet. The sticky feeling is reduced, the refreshing feeling is improved, and the user is not easy to have a visual unpleasant feeling.

In the aspect 9, the blood modifying agent is, for example, the following (i) to (iii): (i) a hydrocarbon; (ii) a CC having (ii-1) a hydrocarbon moiety and (ii-2) the aforementioned hydrocarbon moiety; a compound of one or more of the same or different groups selected from the group consisting of a carbonyl group (-CO-) and an oxy group (-O-) inserted between the single bonds; and (iii) having (iii-1) a hydrocarbon a portion or a plurality of identical or different groups selected from the group consisting of a carbonyl group (-CO-) and an oxy group (-O-) inserted between the CC single bond of the hydrocarbon moiety (iii-2) And (iii-3) a carboxyl group (-COOH) and a hydroxyl group (-) which replace the hydrogen atom of the aforementioned hydrocarbon moiety OH) a compound selected from one or a plurality of identical or different groups selected in the group; and a group consisting of any combination thereof, wherein, in the compound of (ii) or (iii), When two or more oxy groups are inserted, each oxy group is not adjacent (the aspect 10).

In the aspect 9 or 10, the blood modifying agent is, for example, the following (i') to (iii'): (i') hydrocarbon; (ii') has (ii'-1) hydrocarbon moiety, and (ii' -2) a carbonyl bond (-CO-), an ester bond (-COO-), a carbonate bond (-OCOO-), and an ether bond (-O-) inserted between the CC single bonds of the aforementioned hydrocarbon moiety One or a plurality of identical or different bonded compounds selected in the group; and (iii') a CC single having (iii'-1) hydrocarbon moiety and (iii'-2) the aforementioned hydrocarbon moiety One or plural selected from the group consisting of a carbonyl bond (-CO-), an ester bond (-COO-), a carbonate bond (-OCOO-), and an ether bond (-O-) inserted between the bonds One or a plurality of identical or different linkages, one or more selected from the group consisting of (iii'-3) a carboxyl group (-COOH) and a hydroxyl group (-OH) replacing a hydrogen atom of the aforementioned hydrocarbon moiety And a compound consisting of any combination thereof, wherein, in the compound of (ii') or (iii'), when two or more identical or different bonds are inserted, each The bonds are not adjacent (Stage 11).

In the aspects 9 to 11, the blood modifying agent is, for example, 2 to 4 having a chain hydrocarbon portion and a hydrogen atom replacing the aforementioned chain hydrocarbon portion by (A) to (F): (A) (A1) a compound having a hydroxyl group and (A2) an ester having a chain hydrocarbon moiety and a compound which substitutes one carboxyl group of a hydrogen atom of the chain hydrocarbon moiety; (B) (B1) has a chain hydrocarbon moiety and a substituted chain a compound having 2 to 4 hydroxyl groups of a hydrogen atom of a hydrocarbon moiety and (B2) an ether having a chain hydrocarbon moiety and a compound having one hydroxyl group substituted for the hydrogen atom of the chain hydrocarbon moiety; (C) (C1) containing a chain a hydrocarbon moiety, a carboxylic acid, a hydroxy acid, an alkoxy acid or a pendant oxyacid which replaces 2 to 4 carboxyl groups of a hydrogen atom of the aforementioned chain hydrocarbon moiety, and (C2) has a chain hydrocarbon moiety and a substituted chain hydrocarbon An ester of a compound having a hydroxyl group of a part of a hydrogen atom; (D) an ether bond (-O-) having a chain hydrocarbon moiety interposed between a CC single bond of the aforementioned chain hydrocarbon moiety, and a carbonyl bond (-CO-) ), an ester bond (-COO-), and a carbonate bond (-OCOO-) according to any of the groups selected from a compound bonded; (E) polyoxy C _{2 ~ 6} alkyl diol, or an alkoxy a base ester or an alkyl ether; and (F) a chain hydrocarbon; And any combination of their being in the selected groups (aspect 12).

In the aspects 9 to 12, the blood modifying agent is, for example, an ester of (a ₁ ) chain hydrocarbon tetraol with at least one fatty acid, (a ₂ ) chain hydrocarbon triol and at least one fatty acid ester, (a ₃ ) an ester of a chain hydrocarbon diol with at least one fatty acid, (b ₁ ) a chain hydrocarbon tetraol and at least one aliphatic monohydric alcohol ether, (b ₂ ) a chain hydrocarbon triol and at least one fat a hydrocarbon of a monohydric alcohol, (b ₃ ) a chain hydrocarbon diol and an ether of at least one aliphatic monohydric alcohol, (c ₁ ) a chain hydrocarbon tetracarboxylic acid having four carboxyl groups, a hydroxy acid, an alkoxy group An acid or an acid ester of a oxo acid with at least one aliphatic monohydric alcohol, (c ₂ ) a chain hydrocarbon tricarboxylic acid having three carboxyl groups, a hydroxy acid, an alkoxy acid or a oxo acid and at least one aliphatic a monohydric alcohol ester, (c ₃ ) a chain hydrocarbon dicarboxylic acid having two carboxyl groups, a hydroxy acid, an alkoxy acid or a side acid and an ester of at least one aliphatic monohydric alcohol, (d ₁ ) fat An ether of a monohydric alcohol and an aliphatic monohydric alcohol, (d ₂ )dialkyl ketone, an ester of a (d ₃ ) fatty acid and an aliphatic monohydric alcohol, (d ₄ ) a dialkyl carbonate, (e ₁ ) polyoxy C _{2 ~ 6} alkanediols, (e ₂₎ polyoxy C _{2 ~ 6} alkylene glycol and at least one ester of fatty acid, (e ₃₎ polyoxy C _{2 ~ 6} alkanediol Ether least one of an aliphatic monohydric alcohol, (e ₄₎ polyoxy C _{2 ~ 6} alkylene glycol and a chain hydrocarbon tetracarboxylic acid, chain hydrocarbon tricarboxylic acid, a dicarboxylic acid of chain hydrocarbon or ester, ( e ₅ ) polyoxy C _2-6 alkanediol and chain hydrocarbon tetraol, chain hydrocarbon triol, or ether of chain hydrocarbon diol, and (f ₁ ) chain alkane, and any combination thereof Selected in the group (Stage 13).

In the absorbent article of the present invention, the combination can be 1 to 13 More than two kinds of patterns.

The type and use of the absorbent article of the present invention are not special Do not limit, but for example, sanitary napkins, sanitary pads, disposable diapers, incontinence pads, incontinence pads, sweating sheets and other sanitary products. Physiological items, such as human beings, or animals other than people such as pets. The liquid to be absorbed by the absorbent article is not particularly limited, for example, use Liquid excrement, body fluid, etc.

Hereinafter, an embodiment of the absorbent article of the present invention will be described using a sanitary napkin as an example.

<First embodiment>

As shown in FIG. 1 and FIG. 2, the sanitary napkin 1 of the first embodiment includes a liquid-permeable top sheet 2, a liquid-impermeable back sheet 3, and a top sheet 2 and a back sheet 3. Absorber 4.

In Fig. 1, the X-axis direction is the width of the sanitary napkin 1 The direction and the Y-axis direction are the longitudinal direction of the sanitary napkin 1 and the direction of the plane of the X-axis Y-axis is the plane direction of the sanitary napkin 1 . The same is true in other figures. Further, in Fig. 1, the mesh-like flexible region 22 formed in a slightly overall shape of the top sheet 2 and the stretchable region 21 in each mesh are omitted, and in Fig. 2, the bellows formed in the top sheet 2 is omitted. Part 210.

Physiological cotton 1 for absorbing liquid excretions (especially Blood) is used by the user for the purpose. At this time, the top sheet 2 is placed on the skin side of the user, and the back sheet 3 is placed on the side of the user's clothes (underpants), and is used by the user. The liquid excrement is absorbed through the top sheet 2 to the absorber 4 and absorbed by the absorber 4. Reserved. Absorbed by the absorber 4. Leakage of the retained liquid excrement is prevented by the back sheet 3.

As shown in Figure 1 and Figure 2, the top sheet 2 and the back are thin The sheet 3, the end portions in the longitudinal direction are joined to each other by the sealing portions 7a, 7b, and the body portion 11 is formed, while the end portions in the width direction are joined to each other by the sealing portions 8a, 8b to form a substantially rectangular shape extending from the main body portion 11 in the width direction. Wing Parts 12a, 12b. The peripheral portions of the top sheet 2 and the back sheet 3 are joined by the sealing portions 7a, 7b, 8a, 8b to prevent separation of the sheets when the sanitary napkin 1 is deformed.

The shape of the body portion 11 can be matched with the body of the woman. The range of pants and the like is suitably changed, and may be, for example, a slightly rectangular shape, a slightly elliptical shape, or a slightly gourd shape. The extension of the main body portion 11 in the longitudinal direction is usually 100 to 500 mm, preferably 150 to 350 mm, and the extension of the main body portion 11 in the width direction is usually 30 to 200 mm, preferably 40 to 180 mm.

The joint pattern of the sealing portions 7a, 7b, 8a, 8b can be exemplified Such as embossing, ultrasonic, hot melt adhesives and so on. In order to increase the bonding strength, two or more bonding patterns may be combined (for example, embossing or the like after bonding by a hot-melt type adhesive).

Embossing processing, for example, making the top sheet 2 and the back The sheet 3 is embossed by a patterning embossing roll and a flat roll (referred to as a so-called Round seal method). In this method, since the sheets are softened by the heating of the embossing roll and/or the flat roll, the sealing portion is apparently easily formed. The embossed pattern may be, for example, a lattice pattern, a staggered pattern, or a wavy pattern. At the boundary of the sealing portion, the sanitary napkin 1 becomes less likely to be bent, and the embossed pattern is preferably intermittent or elongated.

Hot melt adhesive, for example, styrene-ethylene-butyl Rubber such as styrene-styrene (SEBS), styrene-butadiene-styrene (SBS), styrene-isoprene-styrene (SIS), or the like, or a linear low-density polymer A pressure-sensitive adhesive in which an olefin such as ethylene is a main component Or a heat-sensitive adhesive; a feeling of a water-soluble polymer (for example, polyvinyl alcohol, carboxymethyl cellulose, gelatin, etc.) or a water-swellable polymer (for example, polyvinyl acetate, sodium polyacrylate, etc.) Aqueous adhesives, etc. Examples of the coating method of the subsequent agent include spiral coating, applicator coating, curtain coater coating, and SUMMITGUN coating.

As shown in Figure 2, at the back forming the wings 12a, 12b Adhesive portions 9a, 9b are provided on the garment side of the sheet 3, and an adhesive portion 9c is provided on the garment side of the back sheet 3 on which the main body portion 11 is formed. The adhesive portion 9c is adhered to the crotch portion of the undergarment, and the wings 12a, 12b are bent on the outer side of the undergarment, and the adhesive portions 9a, 9b are adhered to the crotch portion of the undergarment, and the sanitary napkin 1 is stably fixed to the undergarment.

Adhesives contained in the adhesive portions 9a, 9b, and 9c can be exemplified Styrene such as styrene-ethylene-butylene-styrene block copolymer, styrene-butene polymer, styrene-butene-styrene block copolymer, styrene-isobutylene-styrene copolymer Polymer; C5-based petroleum resin, C9-based petroleum resin, dicyclopentadiene petroleum resin, rosin-based petroleum resin, polydecene resin, terpene phenol resin, etc.; adhesion agent; tricresyl phosphate, benzene A monomer plasticizer such as dibutyl formate or dioctyl phthalate; a polymer plasticizer such as an ethylene polymer or a polyester.

The top sheet 2 is provided on the surface in contact with the user's skin for the purpose of enhancing the skin contact when the user uses the sanitary napkin 1.

As shown in FIG. 1 and FIG. 2, in the top sheet 2, the excrement supply area 20 for receiving the supply of liquid excretion from the user is set. The excrement supply area 20 includes an excretory opening that contacts the user (for example) The first region 20a of the labia minora, the labia majora, the vaginal opening, and the like, and the second region 20b located around the first region 20a, the length of the excrement supply region 20, usually 50 to 200 mm, preferably 70 ~150mm, width is usually 10~80mm, preferably 20~50mm. The first region 20a is configured to increase the absorbency of the liquid excrement, and is larger than the excretory opening region of the user actually contacting the user. The second region 20b is disposed around the first region 20a in order to prevent leakage of liquid excrement from the first region 20a that is not absorbed. The second region 20b is particularly effective in preventing leakage from the width direction of the sanitary napkin 1 in the leakage of the liquid exudates that are not absorbed from the first region 20a.

In the present embodiment, as the top sheet 2, as shown in FIG. And the liquid permeable sheet S shown in Fig. 4 . In addition, in the longitudinal direction and the width direction of the liquid permeable sheet S, respectively, the longitudinal direction (Y-axis direction) and the width direction (X-axis direction) of the sanitary napkin 1 are matched.

The liquid permeable sheet S is composed of a flexible material. can The flexible material is a material having an elastic restoring force (rebounding force) to deformation. Although the flexible material can be stretched by the force applied during deformation, it is preferable that the elastic restoring force against deformation is substantially not stretched by the force applied during the deformation.

Flexible material, for example, synthetic resin, synthetic tree The grease may, for example, be a copolymer of an olefin with another monomer such as an acrylate or a vinyl acetate; a polyolefin of a low density polyethylene, a linear low density polyethylene, a high density polyethylene, a polypropylene, or the like; a polyethylene to benzene Polycarboxylate Ester; polyacetamide; cellulose acetate, etc., etc., in view of high flexibility and little irritation to the skin, a copolymer of an olefin and another monomer, a polyolefin, or the like is preferred. The flexible material is a mixed material of two or more kinds of synthetic resins, for example, a mixed material of 20 to 60% of low-density polyethylene, 30 to 60% of linear low-density polyethylene, and 5 to 20% of high-density polyethylene. .

As shown in Fig. 3, in the liquid permeable sheet S, The excrement is supplied to the entire area of the supply region 20, and the flexible region 22 is formed in a mesh shape, and the stretchable region 21 is formed inside each of the meshes.

As shown in FIG. 3 and FIG. 4, in the stretchable region 21, the shape A snake abdomen 210 having a repeating structure of a mountain fold and a valley fold is formed. By the mountain fold and the valley fold being stretched, the snake belly 210 becomes stretchable in the direction of the stretchable region 21. In addition, in FIG. 4, when the top sheet 2 side is the upper side and the back sheet 3 side is the lower side, the upper side convex part is a mountain fold part, and the lower side convex part is a valley fold part.

As shown in Figure 3 and Figure 4, the mountain part of the snake abdomen 210 The valley-folding portions are extended in the longitudinal direction of the liquid-permeable sheet S, and are arranged side by side in the width direction of the liquid-permeable sheet S. With this arrangement, the snake abdomen 210 becomes easy to extend in the width direction of the sanitary napkin 1 and the sanitary napkin 1 is bent along the longitudinal direction and convexly deformed toward the top sheet 2 side, thereby preventing the absorbent body 4 from being deformed. The secondary stretching of the over-compressed snake abdomen 210 is effectively generated.

As shown in Fig. 4, along the width of the liquid permeable sheet S The cross section of the snake's abdomen 210 in the direction is slightly wavy. In the slightly wavy shape, the U-shaped curve is made straight, and the U-shaped is inverted C. The shape is a shape in which the U shape is deformed such as a V shape.

The width of the uppermost part of the mountain fold and the width of the lowermost part of the valley fold Usually 0.1 to 2.0 mm, preferably 0.2 to 1.5 mm, the height of the mountain fold and the depth of the valley fold are usually 0.3 to 3.0 mm, preferably 0.5 to 1.5 mm, and the most adjacent mountain folds are The width of the upper portions and the width of the lowermost portions of the adjacent valley-folding portions are usually 0.3 to 3.0 mm, preferably 0.5 to 2.0 mm.

The snake abdomen 210 can also have contractility in addition to stretchability. However, even when the snake abdomen 210 has contractility, the stretched snake abdomen 210 does not completely contract to its original state and maintains a slightly extended state than the original state due to the material of the snake abdomen 210 and the number of the bellows.

When the snake abdomen 210 is contracted, it constitutes a liquid The elastomer material may be mixed with the flexible material of the permeable sheet S. Examples of the elastomer include polyester-based, urethane-based, olefin-based, styrene-based, polyamido-based thermoplastic elastomers, low-density polyethylene using a metallocene catalyst, and ethylene-α- Olefin copolymers, combinations of these, and the like.

The polyester elastomer may, for example, be an aromatic polyester-containing hard The chain link, the amorphous polyether, the aliphatic polyester is equal to the soft chain link, and the urethane type elastomer is, for example, a polyester as a thermoplastic elastomer, a low molecular weight diol, and a methyl bisexene. Examples of the polyurethane-based elastomer such as phenyl isocyanate and the olefin-based elastomer include a random copolymer of ethylene and an α-olefin, a random copolymer of ethylene and an α-olefin and a diene, and the like. The elastomer may be, for example, a block copolymer such as SEBS, SIS, SEPS or SBS, and the polyamine-based elastomer may contain, for example, a hard chain segment. Dragons and polyesters or polyols as soft links.

As shown in FIG. 3 and FIG. 4, the flexible regions 22 extending in a direction intersecting the liquid permeable longitudinal direction of the sheet S, the substantially straight shape substantially parallel to the m juxtaposed regions (hereinafter referred to as "region A _{1 -m} "), n-shaped areas (hereinafter referred to as "area B _1-n ") which are arranged in a direction slightly parallel to the area A _1-m and which are arranged in parallel, and the area A _1-m and the area B _1-n becomes mesh-like due to the intersection.

The angle α _{1 at} which the region A _1-m intersects with the longitudinal direction of the liquid-permeable sheet S is usually 1 ° ≦ α ₁ ≦ 90 °, preferably 10 ° ≦ α ₁ ≦ 80 °, and more preferably 30 ° ≦ α ₁ ≦ 60 °, the region B _1-n of the liquid crossing through the length of the sheet S in the direction of an angle α ₂ (however, the region B _1-n and the angle a _1-m intersection of region α ₁ + α _2), It is usually 1 ° ≦ α ₂ ≦ 90 °, preferably 10 ° ≦ α ₂ ≦ 80 °, and more preferably 30 ° ≦ α ₂ ≦ 60 °. However, the choice of α ₁ and α ₂ does not make α ₁ + α ₂ 180°. When α ₁ and α _{2 are} in the above range, the size of each mesh necessary for the formation of the snake abdomen 210 is ensured. Further, when the liquid permeable sheet S is attached to the sanitary napkin 1 as the top sheet 2, the region A _1-m and the region B _1-n are located on both sides of the physiological napkin 1 in the longitudinal direction. When the sanitary napkin 1 is bent and deformed in the longitudinal direction, the elastic deformation force (rebounding force) of the flexible region 22 is easily exhibited for the convex deformation.

The number (n) of the regions A _{1-m and} the number (n) of the regions B _1-n are not limited to the numbers shown in FIG. 3, and may be appropriately changed depending on the size of the liquid permeable sheet S and the like. m and n are the same or different values, and the numerical ranges of m and n are usually 4 to 60, preferably 8 to 40, and more preferably 10 to 35.

The width of each of the regions A _1-m and the regions B _1-n is usually 0.1 to 5 mm, preferably 0.3 to 3 mm, and more preferably 0.5 to 2 mm. The width of the region A _1-m and the region B _1-n is in the above range, and the size of each mesh necessary for the formation of the snake abdomen 210 is ensured. In addition, when the sanitary napkin 1 is convexly deformed, the elastic deformation force (rebounding force) of the flexible region 22 is easily exhibited for the convex deformation.

The shape of each mesh formed after the intersection of the region A _1-m and the region B _1-n is a slightly diamond shape as shown in FIGS. 3 and 4 . The present embodiment can also be modified such that the shape of each mesh has a slightly polygonal shape such as a slightly triangular shape, a slightly square shape, or a slightly pentagonal shape. The slightly polygonal shape includes a shape in which a straight line is formed to be rounded, and a straight line constituting one side is deformed into a curve or the like. Further, the present embodiment may be modified such that the regions A _1-m and the regions B _{1-n have} a curved shape, and the shape of each mesh is a substantially circular shape or a slightly elliptical shape.

The size of each mesh formed after the intersection of the region A _1-m and the region B _1-n is generally 3 to 40 mm, preferably 5 to 30 mm, and more preferably the length and width direction of the liquid-permeable sheet S. 10~20mm. The size of each mesh is in the above range, and the size of each mesh necessary for the formation of the snake abdomen 210 is ensured. In addition, when the sanitary napkin 1 is convexly deformed, the elastic deformation force (rebounding force) of the flexible region 22 is easily exhibited for the convex deformation.

The total number of mountain folds and valley folds formed on each mesh, It is usually 3 or more, preferably 5 to 19, and more preferably 7 to 15. However, the total number of mountain folds and valley folds is an odd number. Snake belly 210 mountain folds and valleys When the total number of the folded portions is within the above range, the first stretch of the bellows 210 forming the raised portion 200 is effectively generated, and when the sanitary napkin 1 is convexly deformed, the excessively compressed snake belly 210 of the absorbent body 4 is prevented from being twice. Stretching is effectively generated.

As shown in Figures 3 and 4, the flexible region 22 is surrounded by The entire circumference of the malleable region 21, the connection between the adjacent stretch regions is interrupted by the flexible region 22. This embodiment can also be modified such that a portion of the periphery of the stretchable region 21 is surrounded by the flexible region 22. In this case, in the case of the convex deformation of the sanitary napkin 1, the elastic expansion of the flexible region 22 for effectively preventing the secondary expansion of the bellows 210 preventing the excessive compression of the absorbent body 4 and preventing the deflection of the top sheet 2 is achieved. From the viewpoint of force, the flexible region 22 is preferably 30% or more of the entire circumference of the stretchable region 21, and more preferably 50% or more.

As shown in Figures 3 and 4, the flexible region 22 and the stretch The peripheral portion of the sexual region 21 is continuous. Moreover, as shown in FIG. 4, the flexible region 22 is continuous with the uppermost portion of the mountain fold of the snake belly 210. The present embodiment can also be modified so that the flexible region 22 and the lowermost portion of the valley portion of the bellied abdomen 210 are continuous. However, as shown in FIG. 4, the flexible region 22 is continuous with the uppermost portion of the mountain fold of the snake abdomen 210, as shown in FIG. good.

As shown in FIG. 4, in the liquid permeable sheet S, a complex is formed. The liquid passing through the hole 26 and the liquid excretion can permeate the absorber 4 through the liquid permeation hole 26. As shown in FIG. 4, the liquid permeation hole 26 is formed in the stretchable region 21 where the tension is not directly applied during the convex deformation (the snake abdomen 210) In the middle portion 25) where the uppermost portion of the mountain fold portion is connected to the lowermost portion of the valley fold portion, the flexible region 22 where tension is directly applied during the convex deformation is not formed. Therefore, the liquid permeation hole 26 is less likely to be stretched by the tension, and the absorber 4 that absorbs the liquid excrement is prevented from coming into contact with the skin of the user, giving the user a sticky feeling and an unpleasant feeling.

The opening area of one liquid permeation hole 26 is preferably 0.001 to 1 mm ² , and more preferably 0.01 to 0.1 mm ² . When the opening area of one liquid permeation hole 26 is smaller than 0.001 mm ² , liquid excretion becomes difficult to permeate, and when it exceeds 1 mm ² , liquid excrement absorbed by the absorber 4 passes through the liquid permeation hole 26 . In the case of a reverse flow or a case where the concealing property of the liquid permeable sheet S becomes small.

Total open area of the area relative to the liquid permeable sheet S The ratio of the opening ratio of the liquid permeable sheet S is preferably 5 to 20%. When the opening ratio of the liquid permeable sheet S is less than 5%, the permeability of the liquid excrement in the liquid permeable sheet S is deteriorated. When the aperture ratio of the liquid permeable sheet S exceeds 20%, once The body fluid absorbed by the absorber 4 passes through the liquid permeation hole 26 and flows back through the liquid permeation hole 26 to the liquid excrement absorbed by the absorber 4.

The thickness, the basis weight, and the like of the liquid permeable sheet S are appropriately adjusted from the viewpoints of the formability of the snake abdomen 210 of the stretchable region 21 and the flexibility of the flexible region 22. The basis weight of the liquid permeable sheet S is usually 10 g/m ² or more, preferably 10 to 40 g/m ² , more preferably 20 to 30 g/m ² , and the thickness of the liquid permeable sheet S is usually 0.01 to 3.0. Mm, preferably 0.1 to 1.5 mm.

From the point of view of improving the concealability of the liquid permeable sheet S, the liquid The body permeable sheet S may contain an inorganic filler such as titanium oxide, barium sulfate or calcium carbonate.

The liquid permeable sheet S may be a laminated film. The laminated film may, for example, be a laminated film of a synthetic resin film layer and a fiber assembly layer provided on the side of the garment side. The fiber assembly layer contains, for example, a paper which is an aggregate of hydrophilic fibers, a nonwoven fabric, or the like. The nonwoven fabric used as the fiber assembly layer is preferably a woven fabric. The basis weight of the fabric refers to Kraft pulp, rayon or the like as the main component imparting wet strength of 10g / m ² or more, 20g / m ² or less of the thin paper. The thickness of the fiber collecting layer is preferably 0.1 to 0.5 mm. The fiber assembly layer imparts hydrophilicity and flexibility to the liquid permeable sheet S. In the case where a fabric is used in the fiber assembly layer, the fabric is inexpensive compared to other papers and non-woven fabrics, and is easily obtained because there are many in and out of the market. Although the strength of the fabric layer is low, the strength of the liquid permeable sheet S is ensured by being used together with the synthetic resin film layer.

Back sheet 3 to prevent liquid absorption absorbed by the absorbent body 4 For the purpose of leakage of the waste, it is placed on the surface in contact with the user's clothes (underpants). The back sheet 3 preferably has moisture permeability in addition to liquid impermeability in order to reduce the sultry heat during use.

The back sheet 3 may be, for example, a non-woven waterproofing treatment. a film, a synthetic resin (for example, polyethylene, polypropylene, polyethylene terephthalate, etc.) film, a composite sheet of a non-woven fabric and a synthetic resin film (for example, a synthetic resin film which is bonded to a nonwoven fabric such as spunbond or water entanglement) Composite film), can also use high-strength melt-blown nonwoven fabric with high strength The spunbonded non-woven fabric holds the SMS non-woven fabric and the like.

The absorbent body 4 has a layer of absorbent material. Absorbent material layer The absorbent material contained is not particularly limited as long as it absorbs liquid excretion from the user. Examples of the absorbent material include water-absorbent fibers and superabsorbent materials (for example, superabsorbent resins, superabsorbent fibers, and the like). The absorbent material layer may contain an anti-block agent, an ultraviolet absorber, a bismuth sticking agent, a matting agent, a colorant, and various other modifiers.

The water-absorbent fiber can be, for example, a conifer or a broad-leaved tree. Wood pulp obtained from raw materials (for example, mechanical pulp of crushed wood pulp, refined raw pulp, hot-milled mechanical pulp, chemical hot-milled mechanical pulp, etc.; chemical pulp of kraft pulp, sulfide pulp, alkali pulp, etc.; semi-chemical pulp, etc.) a mercerized pulp or crosslinked pulp obtained by chemically treating wood pulp; non-wood pulp such as bagasse, kenaf, bamboo, hemp, cotton (for example, cotton linters); rayon, fibrillated rayon, etc. Regenerated cellulose; semi-synthetic cellulose such as acetate or triacetate, etc., but it is preferred to pulverize pulp from the viewpoint of low cost and easy forming.

Highly water-absorptive materials, such as starch, cellulose A highly absorbent material based on synthetic polymers. Examples of the starch-based or cellulose-based superabsorbent material include a starch-acrylic acid (salt) graft copolymer, a starch-acrylonitrile copolymer saponified product, and a sodium carboxymethyl cellulose crosslinked product. Examples of the superabsorbent material of the system include polyacrylate type, polysulfonate type, anhydrous maleate type, polypropylene amide type, polyvinyl alcohol type, polyethylene oxide type, poly day. Aspartate, poly Highly water-absorbent resin (SAP) such as glutamate, polyalginate, starch or cellulose, but these are high in polyacrylate (especially sodium polyacrylate). A water-absorbent resin is preferred. The shape of the superabsorbent material is, for example, a particulate form, a fibrous form, or a scaly shape. When it is in the form of particles, the particle diameter is preferably 50 to 1000 μm, and more preferably 100 to 600 μm.

The amount of superabsorbent material contained in the layer of absorbent material, It is preferable to change the characteristics (for example, absorbability, lightness, etc.) which the sanitary napkin 1 should have, and it is usually 0 to 50% by mass, preferably 3 to 30% by mass, and more preferably the absorbent material layer. 5~15% by mass.

The thickness, the basis weight, the density, and the like of the absorbent material layer may be appropriately changed depending on the characteristics (for example, absorbability, lightness, etc.) which the sanitary napkin 1 should have. The thickness of the absorbent material layer is generally 1 ~ 20mm, preferably of 2 ~ 15mm, and more preferably of 2 ~ 10mm, the basis weight is generally 100 ~ 1000g / m ^2, preferably 150 ~ 700g / m ^2, yet more Preferably, it is 200 to 500 g/m ² , and the density is usually 0.005 to 0.5 g/cm ³ , preferably 0.01 to 0.2 g/cm ³ , and more preferably 0.01 to 0.1 g/cm ³ . Further, before and after the formation of the compression grooves 5a, 5b, there are cases where the thickness, the basis weight, the density, and the like of the absorbent material layer are changed (for example, the thickness of the absorbent material layer is reduced, and the basis weight and density are increased).

The absorber 4 can be covered by the covering material but located in the excrement The portion (absorbent bodies 4a, 4b) on the side of the back sheet 3 of the supply region 20 is preferably not covered. The coating material is not particularly limited in terms of liquid permeability and absorber retention, and is low cost and absorbent retention. It is preferable to use a pulverized pulp as a main material and a fabric formed by a wet method.

As shown in Figures 1 and 2, in the top sheet 2, in the row The first region 20a of the waste supply region 20 and the peripheral portion of the second region 20b form compression grooves 5a and 5b, respectively. Since the sanitary napkin 1 is stably deformed convexly by using the compression grooves 5a and 5b as a starting point, when the sanitary napkin 1 is convexly deformed, the secondary stretching of the excessively compressed snake belly 210 of the absorbent body 4 is prevented. The elastic restoring force of the flexible region 22 that prevents the deflection of the top sheet 2 is efficiently generated.

The compression grooves 5a, 5b are embossed by, for example, using a heating roller The processing is performed by compressing and integrating the peripheral portion of the first region 20a and the second region 20b of the excrement supply region 20 and the absorber 4.

As shown in Figures 1 and 2, the compression grooves 5a, 5b are respectively shaped The entire peripheral portion of the first region 20a and the second region 20b of the excrement supply region 20 is formed. The present embodiment may be modified, and the compression grooves 5a, 5b may be formed in a part of the peripheral portion of the first region 20a and the second region 20b of the excrement supply region 20.

The absorber 4 is divided into rows by the compression grooves 5a, 5b The absorber 4a on the back sheet 3 side of the first region 20a of the waste supply region 20 and the absorber 4b on the back sheet 3 side of the second region 20b of the excrement supply region 20 are provided. The thickness of the excrement is supplied to the supply region 20 by the absorber 4a in advance, and since the compression grooves 5a, 5b can induce the stable excrement to be convexly deformed by the supply region 20, the excrement of the user is attached to the supply region 20. Improved compatibility. The absorber 4b is denser than the absorber 4a Since it is easy to maintain rigidity even after the excrement is absorbed, it is prevented from collapsing the entire sanitary napkin 1 after the excrement is absorbed.

The liquid permeable sheet S is in the excrement supply region 20 In the first region 20a, the snake abdomen 210 of the stretchable region 21 is stretched twice, and the stretchable region 21 is formed in such a manner that the raised ridge portion 200 is formed in the thickness direction of the sanitary napkin 1 as shown in the figure. As shown in Fig. 2, in the first region 20a of the excrement supply region 20 of the top sheet 2, a plurality of raised portions 200 are formed in the thickness direction of the sanitary napkin 1.

In the present embodiment, the formation of the compression groove 5a is realized. The formation of the ridges 200. That is, the compressed body 4 compressed at the time of formation of the compression groove 5a is expanded in the direction of the stretchable region 21, so that the snake belly portion 210 of the stretchable region 21 can be stretched once in a stretched manner, so that the stretchable region 21 is used for physiological hygiene. The thickness direction of the cotton 1 is raised. Therefore, as shown in FIG. 2, a portion of the absorber 4 is filled inside the ridge portion 200. The inside of the ridge portion 200 is filled with a portion of the absorber 4, and the shape of the ridge portion 400 at the time of pressurization or the shape of the ridge portion 200 after the liquid exudate is transmitted is easily maintained, so that the top sheet 2 and the use are used. The contact area of the skin is easily maintained at a small value.

The stretch of the snake's abdomen 210 is the highest of the snake's abdomen 210. The large stretch is usually 10 to 80%, preferably 10 to 60%, and more preferably 10 to 50%. When the snake abdomen 210 is stretched in the above range, when the physiological sanitary napkin 1 is convexly deformed, the excessive compression of the absorbent body 4 is effectively prevented by the secondary stretching of the snake annulus 210 which is once stretched.

The liquid permeable sheet S is supplied to the region 20 as excrement The convex deformation is performed, and one portion of the absorbent body 4 is compressed by the elastic restoring force of the flexible region 22 due to the convex deformation, and is compared with the absorbent body filled in the interior of the raised portion 200. In one of the portions 4, a part of the absorber 4 compressed by the elastic restoring force of the flexible region 22 has a high density. By the coarse gradient of the absorber 4, the liquid excrement that has passed through the ridge portion 200 is rapidly moved from the absorber portion filled in the inside of the ridge portion 200 to the absorber body that is compressed by the elastic restoring force of the flexible region 22. section. In particular, in the present embodiment, since the liquid permeation hole 26 is formed in the stretchable region 21, the liquid permeation hole 26 is not formed in the flexible region 22, so that the liquid permeability of the raised portion 200 is improved and moved to the flexibility. The liquid of the absorber portion compressed by the elastic restoring force of the region 22 is less likely to flow back.

In the present embodiment, the formation of the compression groove 5a is realized. The coarse gradient of the absorber 4. That is, at the time of formation of the compression groove 5a, the excrement is convexly deformed (dome-shaped deformation) by the supply region 20, and the body 4 is absorbed by the elastic restoring force of the flexible region 22 due to the convex deformation. Part of it is compressed. Further, the compressed absorbent body 4 is expanded in the direction of the stretchable region 21, and the inside of the raised portion 200 is filled with a portion of the absorbent body 4. Therefore, a part of the absorber 4 compressed by the elastic restoring force of the flexible region 22 has a high density as compared with a portion of the absorber 4 which is filled in the inside of the raised portion 200.

In the sanitary napkin 1, the excrement in the top sheet 2 The supplied area 20 is formed in the thickness direction of the sanitary napkin 1 Since the plurality of ridges 200 are formed, the contact area between the top sheet 2 and the skin of the user becomes small. Therefore, the skin contact of the top sheet 2 is lifted while preventing stickiness, stuffiness, itching, and the like.

Physiological cotton 1 is held in the user's inner stock, at the top When the excrement of the partial sheet 2 is bent by the supply region 20 and is convexly deformed toward the excrement supply region 20 side, as shown in FIG. 5, the snake an abdomen 210 that is stretched once is secondarily stretched, so that it is absorbed. The body 4 becomes less likely to be pressed by the liquid supply region 20, and the excessive compression of the absorbent body 4 caused by the deformation of the sanitary napkin 1 and the subsequent backflow thereof are prevented.

When the sanitary napkin 1 is deformed while changing the bending angle (for example, when the user of the sanitary napkin 1 changes posture, the bending angle of the sanitary napkin 1 becomes an acute angle or an obtuse angle), by being flexible The elastic restoring force (rebounding force) of the sexual region 22, the top sheet 2 is easily deformed by the physiological sanitary napkin 1, so that the deflection and the deflected sheet of the top sheet 2 caused by the secondary stretching of the snake belly 210 are prevented from adhering to the skin.

<Second embodiment>

In the second embodiment, a blood modifying agent is applied to the surface of the top sheet 2 of the sanitary napkin 1 . The menstrual blood discharged from the top sheet 2 has a viscosity and a surface tension which are lowered by the blood modifying agent, so that the top sheet 2 is quickly moved to the absorbent body 4 and absorbed by the absorbent body 4. By the increase in the menstrual blood absorption rate of the absorbent body 4, the top sheet 2 becomes less likely to retain menstrual blood having a high viscosity, so that the sticky feeling of the top sheet 2 is lowered, the surface dryness of the top sheet 2 is improved, and the user becomes difficult I feel uncomfortable visually. and then, The menstrual blood discharged from the top sheet 2 is prevented from leaking from the width direction side of the sanitary napkin 1.

The area where the blood modifying agent is applied may be the top sheet 2 The entire surface or a part of the surface, but preferably includes at least an area contacting the user's excretory opening (vaginal opening). The blood modifying agent preferably adheres the blood modifying agent to the top sheet 2 in the form of droplets or particles so as not to block the liquid permeating holes of the top sheet 2.

The basis weight of the blood modifying agent applied to the top sheet 2 is preferably from 1 to 30 g/m ² and more preferably from 3 to 10 g/m ² . When the coating weight of the blood modifying agent is less than 1 g/m ² , it is difficult to stably apply the blood modifying agent to the top sheet 2, and the coating weight of the blood modifying agent is larger than 30 g/m ² . Then there is a case where the top sheet 2 is slippery.

The coating method of the blood modifying agent can be, for example, heated to a period After the temperature is desired, a method of coating is carried out using a contact coater such as a slit coater, a spray applicator, a curtain coater, or a spiral coater. The method of coating using a non-contact coater is preferred from the viewpoint that the top sheet 2, the droplet-shaped blood modifying agent can be uniformly dispersed, and the top sheet 2 is not damaged.

Coating the blood modifying agent at the time of the top sheet 2 is not special However, it is preferable to apply a blood modifying agent to the top sheet 2 in the manufacturing step of the sanitary napkin 1 from the viewpoint of suppressing equipment investment and the like. When the blood modifying agent is applied to the top sheet 2 in the manufacturing step of the sanitary napkin 1, the blood modifying agent is applied to the top in the step of approaching the final step from the viewpoint of suppressing the reduction of the blood modifying agent. Sheet 2 is preferred. For example, The blood modifying agent is applied to the top sheet 2 immediately before the packaging step of the sanitary napkin 1 is performed.

In the top sheet 2, a region coated with a blood modifying agent can be used. The domain is coated with a hydrophilic agent, a water repellent, or the like, or imparted hydrophilicity by corona treatment, plasma treatment, or the like. Therefore, when the blood modifying agent is lipophilic, in the blood modifying agent application region, the hydrophilic portion and the lipophilic portion become sporadically coexist, and the hydrophilic component (mainly plasma) and lipophilic component of the menstrual blood (main Both of the blood cells are quickly moved from the top sheet 2 to the absorber 4.

Further, the blood modifying agent will be described in detail.

<Method of Manufacturing Absorbent Article>

Hereinafter, an embodiment of a method for producing an absorbent article will be described by taking a method for producing a sanitary napkin as an example.

The manufacturing method of the present embodiment includes a step of forming the absorber 4 (step 1A), a step of laminating the top sheet 2 in the absorber 4 (step 2A), a step of forming a compression groove in the laminate (step 3A), and lamination. a step of the back sheet 3 (step 4A), a step of cutting out the sanitary napkin 1 (step 5A), a step of applying the blood modifying agent to the sanitary napkin 1 (step 6A), and using the method shown in FIG. The device 100 is manufactured.

[Step 1A]

On the circumferential surface of the suction drum 120 that rotates in the machine direction MD, as a model in which the absorber material 122 is filled, the concave portion 124 is formed at a required pitch in the circumferential direction. The suction drum 120 rotates and the recess 124 enters the material for In the feeding portion 121, the suction portion 126 acts on the concave portion 124, and the absorbent material 122 supplied from the material supply portion 121 is vacuum-attracted to the concave portion 124. The material supply unit 121 is formed to cover the suction drum 120. The material supply unit 121 supplies the absorber material 122 to the concave portion 124 by air transportation, and forms the absorber 4 in the concave portion 124. The absorber 4 formed by the recess 124 is transferred onto the carrier sheet 110 that advances in the machine direction MD.

[Step 2A]

The top sheet 2 is laminated to the absorber 4 to form a laminate 262. Moreover, the manufacturing method of the top sheet 2 is mentioned later.

[Step 3A]

The laminate 262 forms a compression groove on the laminate 262 by passing between the upper roller 131 and the lower roller 132 of the embossing device 130. A convex portion (not shown) corresponding to the shape of the compression groove is provided on the outer circumferential surface of the upper roller 131. The lower stage roller 132 is a flat roll having a smooth outer peripheral surface. When the laminate 262 passes between the upper roller 131 and the lower roller 132 of the embossing processing device 130, the laminate 262 is compressed in the thickness direction, and the compression grooves 5a and 5b are formed in the laminate 262. The compression grooves 5a and 5b are formed in the peripheral portion of the first region 20a and the second region 20b of the excrement supply region 20 in the top sheet 2, and the excrement is supplied to the region 20 by the formation of the compression grooves 5a and 5b. The peripheral portion of the first region 20a and the second region 20b is integrated with the absorber 4. At this time, the excrement is deformed into a dome shape by the first region 20a of the supply region 20, and the flexible region is generated by the dome-shaped deformation. The elastic restoring force of the field 21 causes the absorber 4 to be compressed. The compressed absorbent body 4 is expanded in the direction of the stretchable region 21, so that the snake's abdomen 210 of the stretchable region 21 can be stretched once to extend the stretchable region 21 at a time.

[Step 4A]

The back sheet 3 supplied from the back sheet roll 140 is laminated on the lower side of the laminate 134 on which the compression groove is formed (opposite side of the top sheet) through the adhesive layer to form a continuous body 144 of the sanitary napkin 1 .

[Step 5A]

The sterilized body 144 of the sanitary napkin 1 is cut by the cutter 150, and the sanitary napkin 1 is cut out.

[Step 6A]

The sprayer 160 is applied with a blood modifying agent, and the blood modifying agent 161 is applied to the central portion of the sanitary napkin 1 to form a blood modifying agent layer on the surface of the top sheet 2.

a layer of blood modifying agent to form excrement of the top sheet 2 It is preferable that at least the first region 20a of the supply region 20 is provided.

In the present embodiment, the sanitary napkin 1 is cut out. Thereafter, the blood modifying agent is applied, but it may be applied at any stage before the cutting or in the manufacturing step of the top sheet 2 to be described later. In order to prevent the flow of the blood modifying agent applied during the manufacturing process, at a stage downstream of the manufacturing step, for example It is preferred to apply the blood modifying agent before the packaging of the sanitary napkin 1 .

Method for manufacturing physiological sanitary napkin 1 except steps 1A to 6A Further, the steps of forming the sealing portions 7a, 7b, 8a, and 8b, the steps of forming the adhesive portions 9a, 9b, and 9c, and the like are included.

<Method for Producing Liquid Permeable Sheet>

Hereinafter, an embodiment of the method for producing the liquid permeable sheet of the present invention will be described by taking a method of producing the top sheet 2 of the sanitary napkin 1 as an example.

The manufacturing method of the present embodiment includes a step (1B) of forming a concave portion in the synthetic resin film sheet and a step (2B) of extending the synthetic resin film sheet.

[Step 1B]

As shown in Fig. 6, the synthetic resin film sheet 212 supplied from the roller 210 is formed into a concave portion 2141 by the concave portion forming roller 220, and the synthetic resin film sheet 212 is formed (refer to Fig. 8 for reference). The recess forming roller 220 is composed of an embossing roller 221 and a preheating roller 222 having a smooth surface.

7(a) and 7(b) are views showing an example of the embossing roll 221. Fig. 7(a) is a view showing the entirety of the embossing roll 221, and Fig. 7(b) is a view showing the enlarged portion 223 of the outer peripheral surface of the emboss roll 221. Fig. 7 (c) is a view showing an example of the preheating roller 222 having a smooth surface. On the surface 223 of the embossing roll 221, a lattice-like convex portion 224 is provided. Thereby, a rhombic recess 225 is formed on the surface of the embossing roll 221 . Again, embossing roller The shape of the recess 225 of 221 is not limited to a diamond shape, and may be a shape of a square, a rectangle, a parallelogram, a trapezoid, a triangle, a hexagon, or the like.

Among the lattice-like convex portions 224, the convex portions 224 arranged in parallel The center line spacing, that is, the pitch of the lattice-like convex portions 224, is preferably 0.2 to 10 mm, more preferably 0.4 to 2 mm. The width of the lattice-like convex portion 224 is preferably 0.01 to 1 mm, and more preferably 0.03 to 0.1 mm. The length of one side of the rhombic recess 225 is preferably 0.1 to 5 mm, and more preferably 0.2 to 1 mm. The range of these is preferably from the viewpoint of improving the formability of the concave portion of the synthetic resin film sheet.

Preheating roller 222 with smooth surface, maintaining 70 ° C~ The supplied synthetic resin film sheet 212 is heated at a temperature of 100 °C. Thereby, the synthetic resin film sheet 212 becomes soft and can be easily formed.

Synthetic resin film sheet 212 passes between rolls 221 and 222 In the synthetic resin film sheet 212, a portion in contact with the lattice-like convex portion 224 receives a strong pressure in the thickness direction. Thereby, as shown in FIG. 8, a thin concave portion 2141 is formed in the synthetic resin film sheet 214. Further, in actuality, the number of recesses 2141 formed in the synthetic resin film sheet 212 is smaller than that shown in Fig. 8, and the number of recesses 2141 per unit area is larger than that shown in Fig. 8. The concave portion 2141 is formed in the region 2143 of the synthetic resin film sheet 214 corresponding to the central region of the sanitary napkin 1. Further, the region corresponding to the sanitary napkin 1 in the synthetic resin film sheet 214 is a region indicated by a broken line of symbol 2142.

[Step 2B]

By extending the synthetic resin film sheet 214 having the concave portion through the extending tooth roll 230, the region of the synthetic resin film sheet 214 corresponding to the stretchable region 21 of the top sheet 2 is bent, and a synthetic resin film sheet on which the snake belly 210 is formed is produced. 216. In the synthetic resin film sheet 216, the bellied abdomen 210 is extended in the machine direction (MD) and arranged in the width direction, and the shape of the cross section in the width direction is a wave shape in which a substantially U-shaped curve is combined. In the synthetic resin film sheet 216, the snake belly 210 extending in the machine direction is interrupted at a plurality of places. That is, in the synthetic resin film sheet 216, the snake belly portion 210 is formed discontinuously, and in the discontinuous portion, the synthetic resin film sheet 214 is not bent. This discontinuous portion corresponds to the flexible region 22 of the top sheet 2.

The extension tooth roller 230 includes an upper roller 231 and a lower roller 232. Fig. 9(a) is a view for explaining the upper roller 231 of the extension tooth roller 230, and Fig. 9(b) is a view for explaining the gear teeth 233 disposed on the outer circumferential surface of the upper roller 231, and Fig. 9(c) is a view Fig. 9(b) is a cross-sectional view taken along line BB. The gear teeth 233 extend discontinuously in the circumferential direction of the upper roller 231. That is, the gear teeth 233 extending in the circumferential direction of the upper roller 231 are interrupted at a plurality of places. Since the gear teeth 233 are cut at the middle 234, a discontinuous portion corresponding to the flexible region 22 of the top sheet 2 is formed. The cut-away portion 234 of the gear teeth 233 is disposed so as to be aligned on a straight line in a direction in which the direction in which the gear teeth 233 extend is inclined.

The width of the gear teeth 233, for example, 0.3 to 0.5 mm, adjacent The distance between the centers of the gear teeth 233 is, for example, 1.0 to 1.2 mm.

Figure 10 (a) is used to illustrate the lower roller of the extension tooth roller 230 FIG. 10(b) is a view for explaining the gear teeth 235 disposed on the outer circumferential surface of the lower roller 232, and FIG. 10(c) is a cross-sectional view taken along line C-C of FIG. 10(b). The gear teeth 235 extend in the circumferential direction of the lower roller 232. The lower roller 232 does not have the above-described roller 231, and the plurality of places are interrupted. The width of the gear teeth 235 is equal to, for example, the width of the gear teeth 233 of the upper roller 231, and the distance between the centers of the adjacent gear teeth 235 is, for example, equal to the distance between the centers of the gear teeth 233 of the upper roller 231.

Gear teeth 233 of the upper roller 231 and teeth of the lower roller 232 The length of the portion of the upper roller 231 that the teeth 235 engages in the radial direction, that is, the nip depth is, for example, 1.25 mm. The gap between the gear teeth 233 of the upper roller 231 and the gear teeth 235 of the lower roller 232 when the gear teeth 233 of the upper roller 231 are engaged with the gear teeth 235 of the lower roller 232 is, for example, 0.25 to 0.45 mm.

The synthetic resin film sheet 214 passes through the extending tooth roll 230 At the time, in the region 2143 of the synthetic resin film sheet 214 where the concave portion 2141 is formed (see FIG. 8 for reference), an opening portion corresponding to the liquid permeation hole 26 (see FIG. 4 as a reference) of the top sheet 2 is formed.

Referring to Fig. 11, the synthetic resin film sheet 214 is passed through. When the tooth roll 230 is extended, the principle of forming an opening in the synthetic resin film sheet 214 is obtained. Moreover, the principle does not limit the invention.

Synthetic resin film sheet 214 gear of the upper roller 231 The portion 236 where the teeth 233 are engaged with the gear teeth 235 of the lower roller 232 is substantially extended. In the concave portion forming step, the portion in which the concave portion 2141 is formed (refer to FIG. 8 as a reference) is thinned by the synthetic resin film sheet 214, and further The lattice-shaped convex portion 224 of the embossing roll 221 is weak in the portion where the injury is caused, and the concave portion 2141 of the synthetic resin film sheet 214 is broken by being extended. Therefore, in the extending portion 236 of the synthetic resin film sheet 214, the concave portion 2141 of the synthetic resin film sheet 214 is broken, and the broken portion of the synthetic resin film sheet 214 is enlarged to form an opening.

Synthetic resin film sheet 214 in the gear of the upper roller 231 The portions 237, 238 of the teeth 233 and the gear teeth 235 of the lower roller 232 that are not engaged are less extended. Therefore, in the synthetic resin film sheet 214, the gear teeth 233 of the upper roller 231 and the portions 237, 238 where the gear teeth 235 of the lower roller 232 are not engaged, even if the synthetic resin film sheet 214 passes through the extending tooth roller 230, in the above-described concave portion forming step, The formed concave portion 2141 does not break and cannot be an opening portion.

The recess 2141 is not formed in the synthetic resin film sheet 214 In the region 236 where the gear teeth 233 of the upper roller 231 and the gear teeth 235 of the lower roller 232 are engaged, the synthetic resin film sheet 214 is not extended, and the opening portion is not formed.

<blood modifier>

The blood modifying agent of the present invention is a blood modifying agent having a water solubility of about 0.00 to about 0.60 IOB, a melting point of about 45 ° C or less, and a water solubility of about 0.00 to about 0.05 g for 100 g of water at 25 ° C.

IOB (Inorganic Organic Balance) means hydrophilic The indicator of the balance between sex and lipophilicity, in this specification, refers to the Oda Below formula: IOB = inorganic value / organic value

The calculated value. In addition, the inorganic value and the organic value are organic concept maps based on Fujita Mu's "Estimation of Organic Compounds and Organic Concepts" Chemical Region Vol. 11, No. 10 (1957) p. 719-725).

The organic value and inorganic value of the main base of Fujita are as shown in Table 1 below.

For example, in the case of an ester of a tetradecanoic acid having a carbon number of 14 and a dodecyl alcohol having a carbon number of 12, the organic value is 520 (CH ₂ , 20 × 26), and the inorganic value is 60 (-COOR, 60 ×). 1), so IOB=0.12.

In the blood modifying agent of the present invention, although the IOB is about 0.00~ It is about 0.60, preferably about 0.00 to about 0.50, more preferably from about 0.00 to about 0.40, still more preferably from about 0 to about 0.30. Because of the lower IOB, the organicity is high and the affinity with blood cells is increased.

In this specification, the "melting point" indicates the differential scanning heat score. In the analysis, the peak top temperature of the endothermic peak when the solid shape was changed to a liquid state at the temperature increase rate of 10 ° C /min was measured. The melting point can be measured, for example, using a DSC-60 type DSC measuring apparatus manufactured by Shimadzu Corporation.

The blood modifying agent of the present invention has a temperature of about 45 ° C or less The melting point may be a liquid or a solid at room temperature, that is, the melting point may be above about 25 ° C, or less than about 25 ° C, and may, for example, have a melting point of about -5 ° C, about -20 ° C, or the like. The melting point of the blood modifying agent of the present invention is about 45 ° C or less, as will be described later.

The blood modifying agent of the invention has a melting point which does not exist under Limited, but it is better for its low vapor pressure. The blood pressure modifier of the present invention has a vapor pressure of preferably from about 0 to about 200 Pa at 25 ° C (1 atm), more preferably from about 0 to about 100 Pa, more preferably from about 0 to about 10 Pa, still more preferably from about 0 to about 1 Pa. More preferably, about 0.0 to about 0.1 Pa is particularly preferred. The absorbent article is used in contact with the human body. The vapor pressure is preferably from about 0 to about 700 Pa at 40 ° C (1 atm), more preferably from about 0 to about 100 Pa, more preferably from about 0 to about 10 Pa, and even more preferably from about 0 to about 1 Pa. More preferably, it is particularly good from about 0.0 to about 0.1 Pa. When the vapor pressure is high, there is a problem that gasification during storage, a decrease in the amount of the blood modifying agent, and an odor during use are caused.

The melting point of the blood modifying agent of the invention can be adapted to the climate, It varies with the length of time, etc. For example, in an area where the average temperature is about 10 ° C or less, it is considered that by using a blood modifying agent having a melting point of about 10 ° C or lower, the blood modifying agent can stabilize the blood after excretion by blood, even when it is cooled by the ambient temperature. Upgraded.

When the absorbent article is used for a long time, the blood of the present invention The melting point of the liquid modifier is preferably in the range of 45 ° C or less. The blood modifying agent does not easily move even when it is used for a long period of time due to the influence of sweating and friction during use.

The water solubility of 0.00~0.05g can be obtained by using at 25 °C. After adding 0.05 g of the sample to 100 g of deionized water, it was allowed to stand for 24 hours, and after 24 hours, it was gently stirred as necessary, and then visually evaluated whether the sample was dissolved or not.

In addition, in this specification, regarding water solubility, "dissolution" The case where the sample is completely dissolved in deionized water to form a homogeneous mixture, and the sample is completely emulsified. Also, "completely" means a mass that has no sample in deionized water.

In this technical field, to change the surface tension of blood, etc. For the purpose of rapid absorption of blood, the surface of the top sheet was coated with a surfactant. However, since the surfactant generally has high water solubility, the top sheet coated with the surfactant tends to have good compatibility with hydrophilic components (plasma, etc.) in the blood, and tends to cause the blood to remain in the top sheet. It is considered that the blood modifying agent of the present invention has a low water solubility, and unlike conventional surfactants, blood does not remain in the top sheet and can be quickly moved to the absorber.

In the present specification, the solubility in 100 g of water at 25 ° C is referred to as "water solubility".

In the present specification, the "weight average molecular weight" includes a compound derived from a polydisperse system (for example, a compound produced by sequential polymerization, an ester of a plurality of fatty acids and a plurality of aliphatic monohydric alcohols) and a single compound (for example, one type) concept fatty acids with one kind of aliphatic monohydric alcohol esters generated), the mean molecular weight molecules N _i of M _i (i = 1, or i = 1,2 ...) composed of lines, The following formula: M _w =ΣN _i M _i ² /ΣN _i M _i

The obtained M _w .

In this specification, the weight average molecular weight means the colloidal seepage The value of polystyrene conversion obtained by transmission chromatography (GPC).

The measurement conditions of GPC can be exemplified as follows.

Model: High-speed liquid tomography Lachrom Elite by Hitachi High-Technologies

Pipe column: SHODEX KF-801, KF-803 and KF-804 made by Showa Denko Electric Co., Ltd.

Dissolution: THF

Flow rate: 1.0mL/min

Injection volume: 100μL

Detection: RI (differential refractometer)

Moreover, the weight average molecular weight described in the examples of the present specification is measured under the above conditions.

The blood modifying agent of the present invention preferably has the following (i) to (iii), (i) hydrocarbons, (ii) a hydrocarbon having (ii-1) a hydrocarbon moiety, and (ii-2) the above hydrocarbon moiety. Insertion of a single bond between a group of carbonyl (-CO-) and oxy (-O-) One or more of the same or different base compounds selected, and (iii) selected from the group consisting of a carbonyl group (-CO-) and an oxy group (-O-) having a (iii-1) hydrocarbon moiety and a CC single bond interposed between (iii-2) and the above hydrocarbon moiety. One or a plurality of identical or different groups, one or plural selected from the group consisting of a carboxyl group (-COOH) and a hydroxyl group (-OH) substituted with a hydrogen atom of the above hydrocarbon moiety (iii-3) or The compounds of the different bases, and any combination of them, are selected in the group.

In the present specification, the "hydrocarbon" is a compound composed of carbon and hydrogen, and the chain hydrocarbon may, for example, be a liquid paraffinic hydrocarbon (also referred to as an alkane having no double or triple bond) or an olefinic hydrocarbon (also including one). a double bond olefin), an acetylene hydrocarbon (also known as an alkyne having one triple bond), and a bonded hydrocarbon selected from the group consisting of two or more double bonds and triple bonds, and a cyclic hydrocarbon. For example, aromatic hydrocarbons, alicyclic hydrocarbons.

The above hydrocarbons, preferably chain hydrocarbons and alicyclic hydrocarbons, chain hydrocarbons More preferably, paraffinic hydrocarbons, olefinic hydrocarbons, and hydrocarbons having two or more double bonds (excluding triple bonds) are more preferred, and paraffinic hydrocarbons are preferred.

The chain hydrocarbons include a linear hydrocarbon and a branched hydrocarbon.

Among the compounds of (ii) and (iii) above, 2 are inserted. In the case of the above oxy group (-O-), each oxy group (-O-) is not adjacent. Therefore, among the compounds of the above (ii) and (iii), a compound having a continuous oxy group (so-called peroxide) is not contained.

Further, in the compound of the above (iii), compared to the hydrocarbon portion a compound in which at least one hydrogen atom is replaced by a carboxyl group (-COOH), A compound in which at least one hydrogen atom of the hydrocarbon moiety is substituted by a hydroxyl group (-OH) is preferred. As shown in Table 1, since the carboxyl group is bonded to the metal in the hydroxy blood, and the inorganic value is greatly increased from 150 to 400 or more, the blood modifying agent having a carboxyl group has a value of IOB of more than about 0.60 when used. The possibility of a decrease in affinity with blood cells.

More preferably, the blood modifying agent of the present invention has (i') to (iii'), (i') hydrocarbon, (ii') (ii'-1) hydrocarbon moiety, and (ii'-2) The intervening between the CC single bonds of the above hydrocarbon moiety is formed by a carbonyl bond (-CO-), an ester bond (-COO-), a carbonate bond (-OCOO-), and an ether bond (-O-). One or a plurality of identical or different bonded compounds selected in the group, and (iii') having a (iii'-1) hydrocarbon moiety and (iii'-2) a CC single bond intercalation between the hydrocarbon moiety One or a plurality of the same selected from the group consisting of a carbonyl bond (-CO-), an ester bond (-COO-), a carbonate bond (-OCOO-), and an ether bond (-O-) Or a different bond, one or a plurality of the same or different selected from the group consisting of a carboxyl group (-COOH) and a hydroxyl group (-OH) substituted with (iii'-3) a hydrogen atom of the above hydrocarbon moiety The compounds of the group, and any combination thereof, are selected in the group.

In the above compounds (ii') and (iii'), when two or more identical or different linkages are inserted, that is, two or more carbonyl linkages (-CO-) and esters are inserted. The same or different bond junctions of bond (-COO-), carbonate bond (-OCOO-), and ether bond (-O-) The bonds are not adjacent and have at least one carbon atom between the bonds.

The blood modifying agent of the present invention is more preferably a hydrocarbon moiety In the case of 10 carbon atoms, there are about 1.8 or less carbonyl bond (-CO-), 2 or less ester bonds (-COO-), and carbonate bond (-OCOO-) about 1.5 or less, and ether bond. (-O-) is about 6 or less, a carboxyl group (-COOH) of about 0.8 or less, and/or a hydroxyl group (-OH) of about 1.2 or less.

More preferably, the blood modifying agent of the present invention has a chain hydrocarbon moiety and 2 to 4 hydroxyl groups which replace the hydrogen atom of the chain hydrocarbon moiety described below by (A) to (F) and (A) (A1). And (A) a compound having a chain hydrocarbon moiety and a compound which substitutes one carboxyl group of a hydrogen atom of the above-mentioned chain hydrocarbon moiety, (B) (B1) having a chain hydrocarbon moiety and a hydrogen replacing the above chain hydrocarbon moiety; a compound having 2 to 4 hydroxyl groups of an atom and (B2) an ether having a chain hydrocarbon moiety and a hydroxyl group substituted for a hydrogen atom of the chain hydrocarbon moiety; (C) (C1) containing a chain hydrocarbon moiety and a substitution a carboxylic acid, a hydroxy acid, an alkoxy acid or a pendant oxyacid having 2 to 4 carboxyl groups of a hydrogen atom of the above-mentioned chain hydrocarbon moiety and (C2) having a chain hydrocarbon moiety and a hydrogen atom replacing the above chain hydrocarbon moiety An ester of a hydroxyl group compound, (D) having a chain hydrocarbon moiety, an ether bond (-O-), a carbonyl bond (-CO-), an ester bond interposed between a CC single bond of the above chain hydrocarbon moiety ( -COO-), and a compound selected from a group of carbonate linkages (-OCOO-), (E) polyoxy C _2-6 alkanediol, or an alkyl ester or alkyl ether thereof And (F) chain hydrocarbons, and their Any combination is selected in the group.

Hereinafter, the blood modifying agents of (A) to (F) will be described in detail.

[(A) (A1) A compound having a chain hydrocarbon moiety and 2 to 4 hydroxyl groups which replace the hydrogen atom of the above-mentioned chain hydrocarbon moiety, and (A2) having a chain hydrocarbon moiety and a hydrogen atom replacing the above chain hydrocarbon moiety; Ester of a compound of a carboxyl group]

(A) (A1) a compound having a chain hydrocarbon moiety and 2 to 4 hydroxyl groups which replace the hydrogen atom of the above-mentioned chain hydrocarbon moiety, and (A2) 1 having a chain hydrocarbon moiety and a hydrogen atom replacing the above chain hydrocarbon moiety The ester of a compound having a carboxyl group (hereinafter also referred to as "the compound (A)") may have a hydroxyl group which may not be esterified under the above-mentioned IOB, melting point and water solubility.

(A1) having a chain hydrocarbon moiety and replacing the above chain hydrocarbon portion A compound having 2 to 4 hydroxyl groups of a hydrogen atom (hereinafter also referred to as "compound (A1)") may, for example, be a chain hydrocarbon tetraol, for example, an alkanetetraol, for example, pentaerythritol or a chain hydrocarbon triol. For example, alkanol triols, such as glycerol, and chain hydrocarbon diols, such as alkane diols, such as diols.

(A2) A compound having a chain hydrocarbon moiety and one carboxyl group which replaces the hydrogen atom of the above-mentioned chain hydrocarbon moiety (hereinafter also referred to as "compound (A2)"), for example, one hydrogen atom on a hydrocarbon A compound substituted with one carboxy group (-COOH), for example, a fatty acid.

The compound (A) may, for example, be an ester of (a ₁ ) chain hydrocarbon tetraol with at least one fatty acid, (a ₂ ) a chain hydrocarbon triol with at least one fatty acid ester, and (a ₃ ) a chain hydrocarbon. An ester of a diol with at least one fatty acid.

[(a ₁ ) an ester of a chain hydrocarbon tetraol with at least one fatty acid]

The ester of the above chain hydrocarbon tetraol and at least one fatty acid can be exemplified by the following formula (1):

a tetraester of pentaerythritol and a fatty acid, the following formula (2):

a pentaerythritol and a fatty acid triester, the following formula (3):

Diester of pentaerythritol and fatty acid, the following formula (4):

a monoester of pentaerythritol and a fatty acid.

(wherein, R ¹ to R ⁴ are each a chain hydrocarbon)

The fatty acid (R ¹ COOH, R ² COOH, R ³ COOH, and R ⁴ COOH) constituting the ester of pentaerythritol and a fatty acid is not particularly limited as long as the ester of pentaerythritol and a fatty acid satisfies the above requirements of IOB, melting point, and water solubility. For example, a saturated fatty acid, for example, a C ₂ - C ₃₀ saturated fatty acid, such as acetic acid (C ₂ ) (C ₂ represents a carbon number, and is equivalent to a carbon number of R ¹ C, R ² C, R ³ C or R ⁴ C, the same applies hereinafter) , propane acid (C ₃ ), butanoic acid (C ₄ ) and isomers thereof, such as 2-methylpropanic acid (C ₄ ), pentanoic acid (C ₅ ) and isomers thereof, such as 2-A Butyric acid (C ₅ ), 2,2-dimethylpropane acid (C ₅ ), hexane acid (C ₆ ), heptanoic acid (C ₇ ), octanoic acid (C ₈ ) and their isomers For example, 2-ethylhexane acid (C ₈ ), decanoic acid (C ₉ ), decanoic acid (C ₁₀ ), dodecanoic acid (C ₁₂ ), myristic acid (C ₁₄ ), ten Hexanoic acid (C ₁₆ ), heptadecanoic acid (C ₁₇ ), octadecanoic acid (C ₁₈ ), eicosanoic acid (C ₂₀ ), behenic acid (C ₂₂ ), tetracosanoic acid (C ₂₄ ), dihexadecanoic acid (C ₂₆ ), octadecanoic acid (C ₂₈ ), tridecanoic acid (C ₃₀ ), and the like, and the isomers thereof (other than the above).

The above fatty acid may be an unsaturated fatty acid. The above unsaturated fatty acid may, for example, be a C ₃ - C ₂₀ unsaturated fatty acid such as a monounsaturated fatty acid such as crotonic acid (C ₄ ), tetradecenoic acid (C ₁₄ ) or hexadecenoic acid (C _16). ), oleic acid (C ₁₈ ), trans-octadecenoic acid (C ₁₈ ), octadecenoic acid (C ₁₈ ), eicosenoic acid (C ₂₀ ), eicosenoic acid (C ₂₀ ), etc. a di-unsaturated fatty acid such as linoleic acid (C ₁₈ ), eicosadienoic acid (C ₂₀ ), etc., a triunsaturated fatty acid such as linoleic acid, such as α-linolenic acid (C ₁₈ ) and γ- Linoleic acid (C ₁₈ ), pine nut oleic acid (C ₁₈ ), tung oil, such as α-tricoleic acid (C ₁₈ ) and β-ternic acid (C ₁₈ ), metic acid (C ₂₀ ), di- γ - linoleic acid (C ₂₀ ), eicosatrienoic acid (C ₂₀ ), etc., tetraunsaturated fatty acids, such as stearic acid (C ₂₀ ), arachidonic acid (C ₂₀ ), twenty carbon four Acetate (C ₂₀ ), etc., penta-unsaturated fatty acids, such as bosseopentaenoic acid (C ₁₈ ), eicosapentaenoic acid (C ₂₀ ), etc., and some of these hydrogen additions Things.

As the ester of the above pentaerythritol and fatty acid, The possibility of denaturation by oxidation or the like is preferably an ester of pentaerythritol and a fatty acid derived from a saturated fatty acid, that is, an ester of pentaerythritol and a saturated fatty acid.

Further, as the ester of pentaerythritol and a fatty acid, in order to make IOB smaller and more hydrophobic, a diester, a triester or a tetraester is preferred, a triester or a tetraester is more preferable, and a tetraester is more preferable.

In the above tetrakis pentaerythritol and a fatty acid tetraester, the total number of carbon atoms of the fatty acid constituting the tetraester of pentaerythritol and the fatty acid, that is, the R ¹ C, R ² C, R ³ C and R ⁴ C portions in the above formula (1) When the total carbon number is 15, the IOB becomes 0.60. Therefore, in the case where the above-mentioned pentaerythritol and the fatty acid tetraester have a total carbon number of about 15 or more, the IOB satisfies the requirements of about 0.00 to about 0.60.

In the above tetraester of pentaerythritol and a fatty acid, for example, pentaerythritol and hexane acid (C ₆ ), heptanoic acid (C ₇ ), octanoic acid (C ₈ ), for example, 2-ethylhexane acid (C ₈ ) may be mentioned. , nonanoic acid (C _9), capric acid (C ₁₀₎ and / or lauric acid (C ₁₂₎ of the tetraester.

In the above-mentioned formula (2), the total number of carbon atoms of the R ¹ C, R ² C and R ³ C moieties is the total number of carbon atoms of the fatty acid triester of the pentaerythritol and the fatty acid. In the case of 19, the IOB became 0.58. Therefore, in the case where the total number of carbon atoms of the above-mentioned pentaerythritol and fatty acid triester and fatty acid is about 19 or more, the IOB satisfies the requirement of about 0.00 to about 0.60.

In the above formula (3), the carbon number of the R ¹ C and R ² C moieties is 22 in total, in the case where the diester of the pentaerythritol and the fatty acid is a total of the carbon number of the fatty acid of the diester of the pentaerythritol and the fatty acid. The IOB became 0.59. Therefore, in the case where the total number of carbon atoms of the above-mentioned pentaerythritol and fatty acid diester and fatty acid is about 22 or more, the IOB satisfies the requirements of about 0.00 to about 0.60.

In the monoester of pentaerythritol and a fatty acid, the carbon number of the fatty acid constituting the monoester of pentaerythritol and a fatty acid, that is, in the above formula (4), when the carbon number of the R ¹ C moiety is 25, the IOB is 0.60. Therefore, in the case where the above-mentioned pentaerythritol and a monoester of a fatty acid have a carbon number of about 25 or more, the IOB satisfies the requirements of about 0.00 to about 0.60.

Further, in the above calculation, the effects of the double bond, the triple bond, the iso branch, and the tert branch are not considered.

A commercial product of the above-mentioned ester of pentaerythritol and a fatty acid, For example, UNISTAR H-408BRS, H-2408BRS-22 (mixed product), etc. (above, manufactured by Nippon Oil Co., Ltd.).

[(a ₂ ) an ester of a chain hydrocarbon triol with at least one fatty acid]

The ester of the above chain hydrocarbon triol and at least one fatty acid can be exemplified by the following formula (5):

The triglyceride of glycerol and fatty acid, the following formula (6):

The diester of glycerol and fatty acid, and the following formula (7):

(wherein, R ⁵ to R ⁷ are each a chain hydrocarbon)

Monoester of glycerol and fatty acids.

The fatty acid (R ⁵ COOH, R ⁶ COOH, and R ⁷ COOH) constituting the ester of the glycerin and the fatty acid, and the ester of the glycerin and the fatty acid are not particularly limited as long as the above-mentioned IOB, melting point, and water solubility are satisfied, for example, "(a ₁ ) The fatty acid exemplified in the ester of a chain hydrocarbon tetraol and at least one fatty acid, that is, a saturated fatty acid or an unsaturated fatty acid, for example, may be denatured by oxidation or the like, and may be derived from a saturated fatty acid. An ester of glycerin with a fatty acid, that is, an ester of glycerin and a saturated fatty acid is preferred.

Further, in order to make the IOB smaller and more hydrophobic, the ester of the glycerin and the fatty acid is preferably a diester or a triester, and more preferably a triester.

The above triglyceride of glycerol and fatty acid, also known as triglyceride, such as triester of glycerol and octanoic acid (C ₈ ), triester of glycerol and decanoic acid (C ₁₀ ), glycerol and dodecanoic acid (C ₁₂ a triester, and a triester of glycerin with two or three fatty acids, and mixtures thereof.

Examples of the glycerin and the triester of two or more kinds of fatty acids include triglycerides of glycerol and octanoic acid (C ₈ ) and decanoic acid (C ₁₀ ), glycerin and octanoic acid (C ₈ ), and decanoic acid ( C ₁₀ ) and the triester of dodecanoic acid (C ₁₂ ), glycerol and octanoic acid (C ₈ ), decanoic acid (C ₁₀ ), dodecanoic acid (C ₁₂ ), myristic acid (C ₁₄ ), a triester of palmitic acid (C ₁₆ ) and octadecanoic acid (C ₁₈ ).

In the above-mentioned glycerin and fatty acid triester, in order to make the melting point be lower than about 45 ° C, the carbon number of the fatty acid constituting the triester of glycerin and fatty acid is total, that is, in the formula (5), R ⁵ C, R ⁶ C and R ^The total carbon number of the ⁷ C portion is preferably about 40 or less.

Further, in the above-mentioned triglyceride of glycerin and fatty acid, the carbon number of the fatty acid constituting the triester of glycerin and fatty acid is total, that is, the total carbon number of the R ⁵ C, R ⁶ C and R ⁷ C portions in the formula (5) In the case of 12, the IOB becomes 0.60. Therefore, in the case where the total number of carbon atoms of the glycerin and the fatty acid triester and the fatty acid is about 12 or more, the IOB satisfies the requirement of about 0.00 to about 0.60.

The above-mentioned triglyceride of glycerin and fatty acid is a so-called fat, and it is a component of a human body, and it is preferable from a viewpoint of safety.

Commercial products of the above glycerin and fatty acid triester can be exemplified For example, tricocohol fatty acid glyceride, NA36, Panaseate 800, Panasate 800B, and Panasate 810S, and three C2L oil fatty acid glycerides and tri-CL oil fatty acid glycerides (above, manufactured by Nippon Oil Co., Ltd.).

The above diglycerides of glycerol and fatty acid are also called diglycerides, such as diesters of glycerol and decanoic acid (C ₁₀ ), diesters of glycerol and dodecanoic acid (C ₁₂ ), glycerol and palmitic acid (C ₁₆ a diester, and a diester of glycerin and two fatty acids, and mixtures thereof.

In the case where the glycerin and the fatty acid diester are combined with the carbon number of the fatty acid constituting the diester of the glycerin and the fatty acid, that is, in the formula (6), when the total carbon number of the R ⁵ C and R ⁶ C moieties is 16, IOB Become 0.58. Therefore, in the case where the total number of carbon atoms of the glycerin and the fatty acid diester and the fatty acid is about 16 or more, the IOB satisfies the requirements of about 0.00 to about 0.60.

The monoester of the above glycerin and fatty acid is also called a monoglyceride, for example, a monoalcoholic acid (C ₂₀ ) monoester of glycerin, a behenic acid (C ₂₂ ) monoester of glycerin or the like.

In the case where the monoester of glycerin and a fatty acid constitutes a carbon number of a fatty acid which constitutes a monoester of glycerin and a fatty acid, that is, in the formula (7), when the carbon number of the R ⁵ C moiety is 19, IOB is 0.59. Therefore, in the case where the carbon number of the glycerin and the fatty acid monoester and the fatty acid is about 19 or more, the IOB satisfies the requirements of about 0.00 to about 0.60.

[(a ₃ ) an ester of a chain hydrocarbon diol with at least one fatty acid]

The ester of the chain hydrocarbon diol and at least one fatty acid may, for example, be a C ₂ -C ₆ chain hydrocarbon diol, for example, a C ₂ -C ₆ diol such as ethylene glycol, propylene glycol or butylene glycol. a monoester or diester of pentanediol or hexanediol with a fatty acid.

Specifically, the ester of the above chain hydrocarbon diol and at least one fatty acid can be exemplified by the following formula (8): R ⁸ COOC _k H _2k OCOR ⁹ (8)

(wherein, k is an integer from 2 to 6, and R ⁸ and R ⁹ are each a chain hydrocarbon)

a diester of a C ₂ -C ₆ diol and a fatty acid, and the following formula (9): R ⁸ COOC _k H _2k OH (9)

(where k is an integer from 2 to 6, and R ⁸ is a chain hydrocarbon)

a monoester of a C ₂ ~C ₆ diol and a fatty acid.

Among the above-mentioned esters of C ₂ -C ₆ diols and fatty acids, it is desired to esterify fatty acids (in the formulas (8) and (9), which are equivalent to R ⁸ COOH and R ⁹ COOH), C ₂ -C ₆ diols and fatty acids. The ester is not particularly limited as long as it satisfies the above requirements for IOB, melting point and water solubility, for example, the fatty acid listed in "(a ₁ ) chain hydrocarbon tetraol and at least one fatty acid ester", that is, saturated fatty acid and unsaturated For fatty acids, it is preferred to use saturated fatty acids in consideration of the possibility of denaturation by oxidation or the like.

When the total number of carbon atoms of the butanediol (k=4) represented by the formula (8) and the diester of the fatty acid and the R ⁸ C and R ⁹ C moieties is 6, the IOB becomes 0.60. Therefore, in the case where the butanediol (k=4) represented by the formula (8) and the diester of the fatty acid have a total carbon number of about 6 or more, the IOB satisfies the requirements of about 0.00 to about 0.60. Further, in the case of the ethylene glycol (k=2) represented by the formula (9) and the monoester of the fatty acid, and the carbon number of the R ⁸ C moiety is 12, the IOB is 0.57. Therefore, in the case of the ethylene glycol (k=2) represented by the formula (9) and the monoester of the fatty acid, and the carbon number of the fatty acid is about 12 or more, the IOB satisfies the requirement of about 0.00 to about 0.60.

In the case of the above-mentioned ester of a C ₂ -C ₆ diol and a fatty acid, considering the possibility of denaturation by oxidation or the like, an ester of a C ₂ -C ₆ diol derived from a saturated fatty acid and a fatty acid, that is, a C ₂ -C ₆ II Esters of alcohols and saturated fatty acids are preferred.

Further, in terms of the ester of the C ₂ -C ₆ diol and the fatty acid, in order to make the IOB smaller and more hydrophobic, an ester of an alcohol and a fatty acid derived from a diol having a large carbon number, for example, from butanediol or pentane Esters of alcohols and fatty acids of diol or hexanediol are preferred.

Further, in terms of the ester of the C ₂ -C ₆ diol and the fatty acid, in order to make the IOB smaller and more hydrophobic, a diester is preferred.

The commercially available product of the above-mentioned ester of a C ₂ -C ₆ diol and a fatty acid may, for example, be a Cobopol BL or a Cotomboru BS (above, manufactured by Nippon Oil Co., Ltd.).

[(B)(B1) has a chain hydrocarbon moiety and replaces the above a compound having 2 to 4 hydroxyl groups of a hydrogen atom of a chain hydrocarbon moiety and (B2) an ether having a chain hydrocarbon moiety and a compound which substitutes one hydroxyl group of a hydrogen atom of the above chain hydrocarbon moiety]

(B) (B1) a compound having a chain hydrocarbon moiety and 2 to 4 hydroxyl groups which replace the hydrogen atom of the above-mentioned chain hydrocarbon moiety, and (B2) 1 having a chain hydrocarbon moiety and a hydrogen atom replacing the above chain hydrocarbon moiety The ether of a hydroxy group compound (hereinafter also referred to as "compound (B)") may have an ether group which is not completely etherified by having the above-mentioned IOB, melting point and water solubility.

(B1) having a chain hydrocarbon moiety and replacing the above chain hydrocarbon moiety In the compound "A1", for example, pentaerythritol, glycerin, and a diol are mentioned as the compound (A1) in the compound of the 2 to 4 hydroxyl groups of the hydrogen atom.

(B2) a hydrogen atom having a chain hydrocarbon portion and a portion replacing the above chain hydrocarbon portion A compound having one hydroxyl group (hereinafter also referred to as "compound (B2)") may, for example, be a compound in which one hydrogen atom of a hydrocarbon is substituted with one hydroxyl group (-OH), for example, an aliphatic one. Alcohols such as saturated aliphatic monohydric alcohols and unsaturated aliphatic monohydric alcohols.

The saturated aliphatic monohydric alcohol may, for example, be a C ₁ to C ₂₀ saturated aliphatic monohydric alcohol, for example, methyl alcohol (C ₁ ) (C ₁ represents a carbon number, the same applies hereinafter), and ethyl alcohol (C ₂ ) , propyl alcohol (C ₃ ) and isomers thereof, such as isopropyl alcohol (C ₃ ), butyl alcohol (C ₄ ) and isomers thereof, such as sec-butyl alcohol (C ₄ ) and tert- Butyl alcohol (C ₄ ), pentyl alcohol (C ₅ ), hexyl alcohol (C ₆ ), heptyl alcohol (C ₇ ), octyl alcohol (C ₈ ) and isomers thereof, such as 2-ethylhexyl Alcohol (C ₈ ), mercapto alcohol (C ₉ ), mercapto alcohol (C ₁₀ ), dodecyl alcohol (C ₁₂ ), tetradecyl alcohol (C ₁₄ ), hexadecanol (C ₁₆ ), seventeen alcohol (C _17), octadecyl alcohol (C _18), and eicosyl alcohol (C _20), and of these isomers thereof not enumerated.

The above unsaturated aliphatic monohydric alcohol may, for example, be One of the C-C single bonds of the saturated aliphatic monohydric alcohol is substituted with a C=C double bond, such as an oleyl alcohol, for example, New Japan Physical and Chemical Co., Ltd. is sold under the Rikacol series and the Agilent series name.

The compound (B) may, for example, be an ether of a (b ₁ ) chain hydrocarbon tetraol and at least one aliphatic monohydric alcohol, for example, a monoether, a diether, a triether and a tetraether, preferably a diether or a triether. And a tetraether, more preferably a triether and a tetraether, more preferably a tetraether, (b ₂ ) a chain hydrocarbon triol and an ether of at least one aliphatic monohydric alcohol, such as a monoether, a diether and a triether, preferably diether ether and three, three and more preferably an ether, and (b ₃₎ a chain hydrocarbon diol and at least one of an aliphatic monohydric alcohol ethers, monoethers and diethers, for example, and preferably two ether.

The ether of the above chain hydrocarbon tetraol and at least one aliphatic monohydric alcohol can be exemplified by the following formulas (10) to (13):

(wherein R ¹⁰ to R ¹³ are each a chain hydrocarbon.)

The pentaerythritol and the tetraether, triether, diether and monoether of the aliphatic monohydric alcohol.

The ether of the above chain hydrocarbon triol and at least one aliphatic monohydric alcohol can be exemplified by the following formulas (14) to (16):

(wherein R ¹⁴ to R ¹⁶ are each a chain hydrocarbon.)

The triglyceride, diether and monoether of glycerol and aliphatic monohydric alcohol.

The ether of the above chain hydrocarbon diol and at least one aliphatic monohydric alcohol can be exemplified by the following formula (17): R ¹⁷ OC _n H _2n OR ¹⁸ (17)

(wherein, n is an integer from 2 to 6, and R ¹⁷ and R ¹⁸ are each a chain hydrocarbon)

a diether of a C ₂ -C ₆ diol and an aliphatic monohydric alcohol, and the following formula (18): R ¹⁷ OC _n H _2n OH (18)

(wherein, n is an integer from 2 to 6, and R ¹⁷ is a chain hydrocarbon)

a monoether of a C ₂ -C ₆ diol and an aliphatic monohydric alcohol.

In the tetraether of the pentaerythritol and the aliphatic monohydric alcohol, the carbon number of the aliphatic monohydric alcohol constituting the tetraether of the pentaerythritol and the aliphatic monohydric alcohol, that is, R ¹⁰ and R ¹¹ in the above formula (10) When the total carbon number of the R ¹² and R ¹³ portions is 4, the IOB becomes 0.44. Therefore, when the total number of carbon atoms of the above-mentioned pentaerythritol and the aliphatic monohydric alcohol and the aliphatic monohydric alcohol is about 4 or more, the IOB satisfies the requirements of about 0.00 to about 0.60.

The total number of carbon atoms of the aliphatic monohydric alcohol forming the pentaerythritol and the triether of the aliphatic monohydric alcohol in the above-mentioned pentaerythritol and the aliphatic trihydric alcohol triol, that is, in the above formula (11), R ¹⁰ and R ¹¹ When the total carbon number of the R ¹² portion is 9, the IOB becomes 0.57. Therefore, in the case where the total number of carbon atoms of the above-mentioned pentaerythritol and the aliphatic trihydric alcohol and the aliphatic monohydric alcohol is about 9 or more, the IOB satisfies the requirements of about 0.00 to about 0.60.

In the diether of the pentaerythritol and the aliphatic monohydric alcohol, the carbon number of the aliphatic monohydric alcohol constituting the diether of the pentaerythritol and the aliphatic monohydric alcohol, that is, R ¹⁰ and R ¹¹ in the above formula (12) When the total carbon number is 15 in total, the IOB becomes 0.60. Therefore, when the total number of carbon atoms of the above-mentioned pentaerythritol and the aliphatic dihydric alcohol and the aliphatic monohydric alcohol is about 15 or more, the IOB satisfies the requirements of about 0.00 to about 0.60.

The carbon number of the aliphatic monohydric alcohol which constitutes the monoether of pentaerythritol and the aliphatic monohydric alcohol in the monoether of the pentaerythritol and the aliphatic monohydric alcohol, that is, the carbon number of the R ¹⁰ moiety in the above formula (13) For the case of 22, the IOB becomes 0.59. Therefore, in the case where the carbon number of the above-mentioned pentaerythritol and the aliphatic monohydric alcohol and the aliphatic monohydric alcohol is about 22 or more, the IOB satisfies the requirements of about 0.00 to about 0.60.

Further, in the triether of the glycerin and the aliphatic monohydric alcohol, the carbon number of the aliphatic monohydric alcohol constituting the triether of glycerin and the aliphatic monohydric alcohol, that is, R ¹⁴ and R in the formula (14) ^{When the} total carbon number of the ¹⁵ and R ¹⁶ portions is 3, the IOB becomes 0.50. Therefore, when the total number of carbon atoms of the glycerin and the aliphatic trihydric alcohol and the aliphatic monohydric alcohol is about 3 or more, the IOB satisfies the requirements of about 0.00 to about 0.60.

In the diether of the glycerin and the aliphatic monohydric alcohol, the carbon number of the aliphatic monohydric alcohol constituting the diether of the glycerin and the aliphatic monohydric alcohol, that is, the R ¹⁴ and R ¹⁵ portions in the formula (15) When the total carbon number is 9, the IOB becomes 0.58. Therefore, in the case where the total number of carbon atoms of the glycerin and the aliphatic dihydric alcohol and the aliphatic monohydric alcohol is about 9 or more, the IOB satisfies the requirements of about 0.00 to about 0.60.

In the monoether of the glycerin and the aliphatic monohydric alcohol, the carbon number of the aliphatic monohydric alcohol constituting the monoether of the glycerin and the aliphatic monohydric alcohol, that is, in the formula (16), the carbon number of the R ¹⁴ moiety is On the 16th occasion, the IOB became 0.58. Therefore, in the case where the carbon number of the monoglyceride of the glycerin and the aliphatic monohydric alcohol and the aliphatic monohydric alcohol is about 16 or more, the IOB satisfies the requirement of about 0.00 to about 0.60.

When the total number of carbon atoms of the diphenyl diol (n = 4) represented by the formula (17) and the diester of the aliphatic monohydric alcohol and the R ¹⁷ and R ¹⁸ portions is 2, the IOB is 0.33. Therefore, when the total number of carbon atoms of the butanediol (n=4) represented by the formula (17) and the diester of the aliphatic monohydric alcohol and the aliphatic monohydric alcohol is 2 or more, the IOB satisfies about 0.00 to about 0.60. The essentials. Further, in the case of the ethylene glycol (n = 2) represented by the formula (18) and the monoether of the aliphatic monohydric alcohol, when the carbon number of the R ¹⁷ moiety is 8, the IOB is 0.60. Therefore, in the case where the ethylene glycol (n=2) represented by the formula (18) and the monoether of the aliphatic monohydric alcohol and the aliphatic monohydric alcohol have a carbon number of about 8 or more, the IOB satisfies about 0.00 to about 0.60. The essentials.

The compound (B) can be produced by subjecting the compound (B1) and the compound (B2) to dehydration condensation in the presence of an acid catalyst.

[(C) (C1) a carboxylic acid, a hydroxy acid, an alkoxy acid or a oxo acid having a chain hydrocarbon moiety and a 2-4 carboxyl group which replaces the hydrogen atom of the above-mentioned chain hydrocarbon moiety, and (C2) have a chain shape An ester of a hydrocarbon moiety and a compound substituted with one hydroxyl group of a hydrogen atom of the above-mentioned chain hydrocarbon moiety]

(C) (C1) a carboxylic acid, a hydroxy acid, an alkoxy acid or a pendant oxyacid having a chain hydrocarbon moiety and 2 to 4 carboxyl groups which replace the hydrogen atom of the above-mentioned chain hydrocarbon moiety, and (C2) having a chain hydrocarbon An ester of a compound partially substituted with one hydroxyl group of a hydrogen atom of the above-mentioned chain hydrocarbon moiety (hereinafter also referred to as "compound (C)") may have a carboxyl group which may have a carboxyl group having a melting point and a water solubility as described above. Esterification.

(C1) a carboxylic acid, a hydroxy acid, an alkoxy acid or a side oxyacid containing a chain hydrocarbon moiety and a 2-4 carboxyl group which replaces the hydrogen atom of the above-mentioned chain hydrocarbon moiety (hereinafter, also referred to as "compound (C1)" In the case of the chain, a chain hydrocarbon carboxylic acid having 2 to 4 carboxyl groups, for example, a chain hydrocarbon dicarboxylic acid, for example, an alkane dicarboxylic acid such as ethane diacid, propane diacid, butanedioic acid, Pentanedioic acid, hexanedioic acid, heptanedioic acid, octanedioic acid, decanedioic acid and decanedioic acid, chain hydrocarbon tricarboxylic acid, such as an alkanetricarboxylic acid, such as propane triacid, butane Triacid, pentanetricarboxylic acid, hexanetricarboxylic acid, heptanetricarboxylic acid, octanetricarboxylic acid, decanetricarboxylic acid and decanetricarboxylic acid, and chain hydrocarbon tetracarboxylic acid, for example Alkane tetracarboxylic acids, such as butane tetracarboxylic acid, pentane tetracarboxylic acid, hexanetetracarboxylic acid, heptanetetracarboxylic acid, octane tetracarboxylic acid, decanetetracarboxylic acid, and decane tetracarboxylic acid.

Further, the compound (C1) contains 2 to 4 carboxyl groups. a chain hydrocarbon hydroxy acid, such as malic acid, tartaric acid, citric acid, isocitric acid, etc., a chain hydrocarbon alkoxy acid having 2 to 4 carboxyl groups, such as O-ethyl citrate, and having 2 to 4 a carboxyl group-like hydrocarbon side acid.

(C2) The compound having a chain hydrocarbon moiety and a hydroxyl group which replaces the hydrogen atom of the chain hydrocarbon moiety, for example, those listed in "Compound (B)", for example, an aliphatic monohydric alcohol.

The compound (C) may, for example, be (c ₁ ) a chain hydrocarbon tetracarboxylic acid having four carboxyl groups, a hydroxy acid, an alkoxy acid or an ester of a side acid and at least one aliphatic monohydric alcohol, for example, a monoester. , diester, triesters and tetraesters, preferably diesters, triesters and tetraesters, more preferably triesters and triesters, more preferably tetraesters, (c ₂ ) chain hydrocarbons having 3 carboxyl groups An ester of a carboxylic acid, a hydroxy acid, an alkoxy acid or a oxo acid with at least one aliphatic monohydric alcohol, such as a monoester, a diester or a triester, preferably a diester and a triester, and more preferably three. And an ester of (c ₃ ) a chain hydrocarbon dicarboxylic acid having two carboxyl groups, a hydroxy acid, an alkoxy acid or a oxo acid with at least one aliphatic monohydric alcohol, such as a monoester or a diester, Jia is a diester.

Examples of the compound (C) include commercially available products such as dioctyl adipate, tributyl butyl ethoxide and the like.

[(D) has a chain hydrocarbon moiety, and the above chain hydrocarbon moiety Among the C-C single bonds, an ether bond (-O-), a carbonyl bond (-CO-), an ester bond (-COO-), and a carbonate bond (-OCOO-) are selected. Any of the bonded compounds]

(D) an ether bond (-O-), a carbonyl bond (-CO-), an ester bond (-COO-), and a carbonic acid having a chain hydrocarbon moiety and a CC single bond intercalated with the above chain hydrocarbon moiety Any of the compounds selected in the group in which the ester bond (-OCOO-) is selected (hereinafter, also referred to as "compound (D)"), for example, (d ₁ ) aliphatic monohydric alcohol and fat An ether of a monohydric alcohol, a (d ₂ ) dialkyl ketone, an ester of a (d ₃ ) fatty acid and an aliphatic monohydric alcohol, and (d ₄ ) a dialkyl carbonate.

[(d ₁ ) an ether of an aliphatic monohydric alcohol and an aliphatic monohydric alcohol]

The ether of the above aliphatic monohydric alcohol and the aliphatic monohydric alcohol may, for example, have the following formula (19): R ¹⁹ OR ²⁰ (19)

(wherein, R ¹⁹ and R ²⁰ are each a chain hydrocarbon)

Compound.

In the case of the aliphatic monohydric alcohol (equivalent to R ¹⁹ OH and R ²⁰ OH in the formula (19)), the ether is not particularly limited as long as it satisfies the above-mentioned requirements for IOB, melting point and water solubility, and for example, The aliphatic monohydric alcohol exemplified in the compound (B).

In the ether of the aliphatic monohydric alcohol and the aliphatic monohydric alcohol, the total number of carbon atoms of the aliphatic monohydric alcohol constituting the ether, that is, in the above formula (19), the total carbon number of the R ¹⁹ and R ²⁰ moieties is In the case of 2, since the IOB is 0.50, the total number of carbon atoms is about 2 or more, and the requirements of the above IOB are satisfied. However, the total carbon number is about 6, and the water solubility is about 2 g, which is also problematic in terms of vapor pressure. In order to satisfy the requirement that the water solubility is from about 0.00 to about 0.05 g, the total carbon number is preferably about 8 or more.

[(d ₂ )dialkyl ketone]

The above dialkyl ketone may, for example, have the following formula (20): R ²¹ COR ²² (20)

(wherein R ²¹ and R ²² are each an alkyl group)

Compound.

In the case where the total number of carbon atoms of R ²¹ and R ²² is 5, the IOB is 0.54. Therefore, if the total number of carbon atoms is about 5 or more, the requirements of the above IOB are satisfied. However, the total carbon number is about 5, and the water solubility is as high as about 2 g. Therefore, in order to satisfy the requirement that the water solubility is from about 0.00 to about 0.05 g, it is preferred that the total carbon number is about 8 or more. Further, when the vapor pressure is considered, the carbon number is preferably about 10 or more, and more preferably about 12 or more.

Further, when the total carbon number is about 8, for example, 5-nonanone has a melting point of about -50 ° C and a vapor pressure of about 230 Pa at 20 ° C.

The above dialkyl ketone can be obtained by a conventional method, for example, by oxidizing a second-stage alcohol with chromic acid or the like, in addition to a commercially available one.

[(d ₃ ) ester of fatty acid with aliphatic monohydric alcohol]

The ester of the above fatty acid and the aliphatic monohydric alcohol may, for example, have the following formula (21): R ²³ COOR ²⁴ (21)

(wherein, R ²³ and R ²⁴ are each a chain hydrocarbon)

Compound.

The fatty acid constituting the above-mentioned ester (corresponding to R ²³ COOH in the formula (21)) may, for example, be a fatty acid as exemplified in the "(a ₁ ) chain hydrocarbon tetraol and at least one fatty acid ester", that is, a saturated fatty acid. Or unsaturated fatty acids, if considering the possibility of denaturation by oxidation, etc., it is preferable to use a saturated fatty acid. The aliphatic monohydric alcohol (e.g., R ²⁴ OH in the formula (21)) constituting the above-mentioned ester may, for example, be an aliphatic monohydric alcohol as exemplified in the "compound (B)".

In addition, in the case where the carbon number of the fatty acid and the aliphatic monohydric alcohol, the fatty acid and the aliphatic monohydric alcohol are in total, that is, in the formula (21), the total carbon number of the R ²³ C and R ²⁴ moieties is 5 When the IOB is 0.60, the total number of carbon atoms in the R ²³ C and R ²⁴ portions is about 5 or more, and the requirements of the above IOB are satisfied. However, for example, in the case of the above-mentioned butyl acetate having a total carbon number of 6, the vapor pressure is as high as more than 2,000 Pa. Therefore, in consideration of the vapor pressure, it is preferred that the total carbon number is about 12 or more. Moreover, when the total carbon number is about 11 or more, the water solubility is about 0.00 to about 0.05 g.

Examples of the ester of the above fatty acid and the aliphatic monohydric alcohol include, for example, an ester of dodecanoic acid (C ₁₂ ) and dodecyl alcohol (C ₁₂ ), myristic acid (C ₁₄ ) and dodecyl alcohol (C _{12 ).} The commercial product of the ester of the above-mentioned fatty acid and the aliphatic monohydric alcohol is, for example, a Retru WE20 and a Retru WE40 (manufactured by Nippon Oil Co., Ltd.).

[(d ₄ )Dialkyl carbonate]

The above dialkyl carbonate may, for example, have the following formula (22): R ²⁵ OC(=O)OR ²⁶ (22)

(wherein, R ²⁵ and R ²⁶ are each an alkyl group)

Compound.

In the case where the total number of carbon atoms of R ²⁵ and R ²⁶ is 6 in the above dialkyl carbonate, the IOB is 0.57. Therefore, the total carbon number of R ²⁵ and R ²⁶ is about 6 or more to satisfy the requirements of IOB.

When the water solubility is considered, the total carbon number of R ²⁵ and R ²⁶ is preferably about 7 or more, and more preferably about 9 or more.

The above dialkyl carbonates can be synthesized by the reaction of phosgene with an alcohol, the reaction of a chlorinated formate with an alcohol or an alkoxide, and the reaction of silver carbonate with an alkyl iodide, in addition to those commercially available.

[(E) Polyoxygenated C _2-6 alkanediol, or its ester or ether]

The polyoxy C _2-6 alkanediol, or an ester or ether thereof (hereinafter, in the case of the compound (E)), for example, (e ₁ ) polyoxygenated C _2-6 alkanediol, (e ₂ ) polyoxidation An ester of C _2-6 alkanediol with at least one fatty acid, (e ₃ ) a polyoxy C _2-6 alkanediol and an ether of at least one aliphatic monohydric alcohol, (e ₄ ) a polyoxygenated C _2-6 An alkanediol with a chain hydrocarbon tetracarboxylic acid, a chain hydrocarbon tricarboxylic acid, or a chain hydrocarbon dicarboxylic acid ester, and (e ₅ ) a polyoxygenated C _2-6 alkanediol and a chain hydrocarbon tetraol, a chain An ether of a hydrocarbon triol or a chain hydrocarbon diol. The following description will be made.

[(e ₁ ) polyoxygenated C _2-6 alkanediol]

The above polyoxygenated C _2-6 alkanediol refers to i) an oxidized C _2-6 alkene skeleton, that is, having an oxyethylene skeleton, an oxypropylene skeleton, a oxidized butene skeleton, a pentene oxide skeleton, and an oxyhexene oxide. a homopolymer having a skeleton selected from a group of skeletons and having a hydroxyl group at both terminals, ii) a block copolymer having two or more kinds of skeletons selected from the above group and having a hydroxyl group at both terminals, or iii A random copolymer having two or more kinds of skeletons selected from the above groups and having hydroxyl groups at both terminals.

The oxidized C _2-6 alkene skeleton is preferably an oxypropylene skeleton, a oxidized butene skeleton, a pentene oxide skeleton, or an oxyhexene skeleton from the viewpoint of a decrease in IOB of the polyoxygenated C _2-6 alkanediol. The oxidized butene skeleton, the pentene oxide skeleton, or the hexene oxide skeleton is more preferable.

The above polyoxygenated C _2-6 alkanediol can be represented by the following formula (23): HO-(C _m H _2m O) _n -H (23)

(where m is an integer from 2 to 6)

To represent.

Moreover, the inventors confirmed that when polyethylene glycol (the homopolymer of m=2 in the formula (23)) is n≧45 (weight average molecular weight is more than about 2,000), it satisfies about 0.00 to about 0.60. The requirements of the IOB, but even where the weight average molecular weight exceeds about 4,000, the water solubility requirements are not met. Therefore, it is considered that (e ₁ ) polyoxygenated C _2-6 alkanediol does not contain a homopolymer of ethylene glycol, and ethylene glycol should be used as a block copolymer or random copolymer with other diols. Included in (e ₁ ) polyoxy C _2-6 alkanediol.

Therefore, the homopolymer of the formula (23) may contain a homopolymer of propylene glycol, butanediol, pentanediol or hexanediol.

From the above, in the formula (23), m is from about 3 to about 6, more preferably from about 4 to about 6, and n is 2 or more.

In the above formula (23), the value of n is a poly C _2-6 alkanediol having an IOB of from about 0.00 to about 0.60, a melting point of about 45 ° C or less, and a water of from about 0.00 to about 0.05 g for 100 g of water at 25 ° C. The value of the solubility.

For example, when the formula (23) is polypropylene glycol (m=3 homopolymer), when n=12, IOB is 0.58. Therefore, when the formula (23) is a polypropylene glycol (m=3 homopolymer), when m≧ is about 12, the requirements of the above IOB are satisfied.

Further, when the formula (21) is polytetramethylene glycol (m=4 homopolymer), when n=7, IOB is 0.57. Therefore, when the formula (23) is polytetramethylene glycol (m=4 homopolymer), when n≧ is about 7, the requirements of the above IOB are satisfied.

The weight average molecular weight of the polyoxygen C _4-6 alkanediol is preferably from about 200 to about 10,000, more preferably from about 250 to about 8,000, still more preferably from about 250 to about 5,000, from the viewpoints of IOB, melting point and water solubility. The scope.

Further, from the viewpoints of IOB, melting point and water solubility, the weight average molecular weight of the polyoxy C ₃ alkylene glycol, that is, the polypropylene glycol, is preferably from about 1,000 to about 10,000, more preferably from about 3,000 to about 8,000, more preferably. It is in the range of about 4,000 to about 5,000. If the weight average molecular weight is less than about 1000, the water solubility does not conform to the requirements, and the larger the weight average molecular weight, the higher the moving speed of the absorbent and the whiteness of the top sheet tend to increase.

Commercial products of the above-mentioned polyoxygenated C _2-6 alkanediol include, for example, UNIOL (trademark) D-1000, D-1200, D-2000, D-3000, D-4000, PB-500, PB-700, PB-1000 and PB-2000 (above, manufactured by Nippon Oil Co., Ltd.).

[(e ₂ ) an ester of polyoxygenated C _2-6 alkanediol with at least one fatty acid]

The above-mentioned polyoxyalkylene alkylene glycol C _{2 ~ 6} with at least one ester of a fatty acid includes, for example in "(e ₁₎ polyoxy C _{2 ~ 6} alkanediol" described polyoxyalkylene C _{2 ~ 6} alkanediols One or both of the OH ends are esterified with fatty acids, that is, monoesters and diesters.

In the ester of polyoxy C _2-6 alkanediol and at least one fatty acid, the fatty acid to be esterified, for example, the fatty acid listed in "(a ₁ ) chain hydrocarbon tetraol and at least one fatty acid ester", That is, a saturated fatty acid or an unsaturated fatty acid is preferably a saturated fatty acid in consideration of the possibility of denaturation by oxidation or the like.

A commercially available product of the above-mentioned ester of a polyoxy-C _2-6 alkanediol and a fatty acid is, for example, WILBRIDE cp9 (manufactured by Nippon Oil Co., Ltd.).

[(e ₃ ) an ether of polyoxygenated C _2-6 alkanediol and at least one aliphatic monohydric alcohol]

The above-mentioned polyoxyalkylene alkylene glycol C _{2 ~ 6} with at least one of an aliphatic monohydric alcohol ether includes, for example, "(e ₁₎ polyoxy C _{2 ~ 6} alkanediol" described in the polyoxyalkylene C _{2 ~ 6} One or both of the OH ends of the alkanediol are etherified with an aliphatic monohydric alcohol, that is, a monoether and a diether.

In the ether of the polyoxygenated C _{2 - 6} alkanediol and the at least one aliphatic monohydric alcohol, the aliphatic monohydric alcohol to be etherified may, for example, be an aliphatic monohydric alcohol listed in the "compound (B)". .

[(e ₄ ) an ester of polyoxygenated C _2-6 alkanediol with a chain hydrocarbon tetracarboxylic acid, a chain hydrocarbon tricarboxylic acid, or a chain hydrocarbon dicarboxylic acid]

In the ester of the polyoxy C _2-6 alkanediol and the chain hydrocarbon tetracarboxylic acid, the chain hydrocarbon tricarboxylic acid, or the chain hydrocarbon dicarboxylic acid, the polyoxy C _2-6 alkanediol may be esterified. among the Examples as "(e ₁₎ polyoxy C _{2 ~ 6} alkanediol" described polyoxyalkylene C _{2 ~ 6} alkanediol. Further, the chain hydrocarbon tetracarboxylic acid, the chain hydrocarbon tricarboxylic acid, and the chain hydrocarbon dicarboxylic acid are preferably esterified, for example, as described in "(Compound (C)".

The above-mentioned polyoxy C _2-6 alkanediol and an ester of a chain hydrocarbon tetracarboxylic acid, a chain hydrocarbon tricarboxylic acid, or a chain hydrocarbon dicarboxylic acid may be a chain hydrocarbon tetracarboxylic acid or a chain, in addition to a commercially available product. The hydrocarbon hydrocarbon tricarboxylic acid or the chain hydrocarbon dicarboxylic acid and the oxidized C _2-6 alkanediol are produced by polycondensation under a known condition.

[(e ₅ ) polyoxygenated C _2-6 alkanediol and chain hydrocarbon tetraol, chain hydrocarbon triol, or ether of chain hydrocarbon diol]

In the ether of the polyoxy C _2-6 alkanediol and the chain hydrocarbon tetraol, the chain hydrocarbon triol or the chain hydrocarbon diol, the polyoxy C _2-6 alkanediol to be etherified may, for example, be mentioned. among "(e ₁₎ polyoxy C _{2 ~ 6} alkanediol" described polyoxyalkylene C _{2 ~ 6} alkanediol. Further, examples of the chain hydrocarbon tetraol, the chain hydrocarbon triol, and the chain hydrocarbon diol to be etherified include "the compound (A)", for example, pentaerythritol, glycerin, and a diol.

Commercial products of the above-mentioned polyoxy C _2-6 alkanediol and a chain hydrocarbon tetraol, a chain hydrocarbon triol or a chain hydrocarbon diol may, for example, be UNILUBE (trademark) 5 TP-300 KB, and UNIOL ( Trademarks) TG-3000 and TG-4000 (made by Nippon Oil Co., Ltd.).

UNILUBE (trademark) 5TP-300KB is a compound which polycondenses pentaerythritol 1 molar with propylene glycol 65 mole and ethylene glycol 5 mole. Its IOB is 0.39, the melting point is less than 45 ° C, and the water solubility is less than 0.05 g.

Uniol (trademark) TG-3000 is glycerol 1 molar and propylene An alcohol 50 molar condensation product having an IOB of 0.42, a melting point of less than 45 ° C, a water solubility of less than 0.05 g, and a weight average molecular weight of about 3,000.

Uniol (trademark) TG-4000 is a compound in which glycerol 1 molar is condensed with propylene glycol 70, having an IOB of 0.40, a melting point of less than 45 ° C, a water solubility of less than 0.05 g, and a weight average molecular weight of about 4,000.

The polyoxy C _2-6 alkanediol and the chain hydrocarbon tetraol, the chain hydrocarbon triol, or the ether of the chain hydrocarbon diol can be further obtained by chain hydrocarbon tetraol, chain hydrocarbon triol, or The chain hydrocarbon diol and C _2-6 alkylene oxide are produced by addition under conventional conditions.

[(F) chain hydrocarbon]

The chain hydrocarbon may be contained in the blood modifying agent because the inorganic value is 0, the IOB is 0.00, and the water solubility is about 0 g. Therefore, the melting point is about 45 ° C or lower. The chain hydrocarbon may, for example, be a (f ₁ ) chain alkane, for example, a linear alkane or a branched alkane. For example, in the case of a linear alkane, when the melting point is about 45 ° C or less, the carbon number is preferably 22 or less. Further, when the vapor pressure is considered, it is likely to contain a carbon number of 13 or more. In the case of a branched paraffin, since the melting point is low in the same carbon number as the linear alkane, the carbon number may be 22 or more.

The commercial product of the above hydrocarbons may, for example, be PARLEAM6 (Nippon Oil Co., Ltd.).

The blood modifying agent of the invention is tested in detail together with the embodiment It was found to have at least a role in lowering blood viscosity and surface tension. The menstrual blood to be absorbed by the absorbent article is compared with the general blood, and the blood cells are connected to each other by the proteins such as the endometrial wall, and the blood cells are easily in a state of continuous alignment. Therefore, when the menstrual blood to be absorbed by the absorbent article tends to become highly viscous and the top sheet is non-woven or woven, the menstrual blood tends to block between the fibers, and the user tends to feel sticky, and the blood spreads on the surface of the top sheet. It becomes easy to leak. In this case, by applying the blood modifying agent of the present invention to the top sheet, the menstrual blood between the fibers of the top sheet is not easily blocked, and the menstrual blood can be quickly moved from the top sheet to the absorbent body.

The blood of the present invention is considered to have an IOB of from about 0.00 to about 0.60. The modifier is high in organicity and easily enters the blood cells, so that the blood cells can be stabilized and the blood cells are not easily formed into a chain structure. It is considered that the blood modifying agent of the present invention makes it easy to absorb menstrual blood by calming the blood cells and making the blood cells difficult to form a linked structure. For example, an acrylic high-absorbent polymer is known, that is, in an absorbent article containing SAP, which absorbs menstrual blood, the continuously arranged blood cells coat the surface of the SAP, and it becomes difficult for SAP to exert absorption performance, but by stabilizing the blood cells, SAP It becomes easy to exert absorption performance. Further, it is considered that the red blood cell membrane is not easily destroyed by the blood modifying agent having a high affinity with red blood cells to protect the red blood cell membrane.

The blood modifying agent of the present invention has a weight of about 2000 or less The amount average molecular weight is preferably and the weight average molecular weight of 1,000 or less is more preferable. When the weight average molecular weight is increased, the viscosity of the blood modifying agent becomes difficult to fall to a viscosity suitable for coating, and it is required to be diluted with a solvent. Moreover, when the weight average molecular weight is increased, the blood modifying agent is sticky and imparted The situation of unpleasant feelings.

According to the following examples, it was confirmed that the blood modifying agent has a function of lowering the viscosity and surface tension of blood.

[Examples]

Hereinafter, the present invention will be exemplified, but the present invention is not limited to these examples.

〔example 1〕 [Data of blood modifying agent]

Prepare commercially available sanitary napkins. The sanitary tampon is a top sheet formed by a hot air non-woven fabric treated with a hydrophilic agent (composite fiber composed of polyester and polyethylene terephthalate, basis weight: 35 g/m ² ), and hot air non-woven fabric (poly a composite sheet composed of an ester and a polyethylene terephthalate, a basis weight: 30 g/m ² ), a second sheet, a pulp (basis weight: 150 to 450 g/m ² , a large central portion), and acrylic acid It is formed of a high-absorbent polymer (basis weight: 15 g/m ² ) and a back sheet composed of an absorbent body as a core cladding fabric, a water-repellent-treated side sheet, and a polyethylene film.

The blood modifying agents used in the experiments are listed below.

[(a ₁ ) an ester of a chain hydrocarbon tetraol with at least one fatty acid]

. UNISTAR H-408BRS, manufactured by Nippon Oil Co., Ltd.

Tetrakilyl tetraethyl 4-hexyl carboxylate, weight average molecular weight: about 640

. UNISTAR H-2408BRS-22, manufactured by Nippon Oil Co., Ltd.

Tetrakilyl tetraethyl 2-ethyl hexane acid and neopentyl di 2-ethyl hexane acid Mixture of diols (58:42, weight ratio), weight average molecular weight: about 520

[(a ₂ ) an ester of a chain hydrocarbon triol with at least one fatty acid]

. Cetiol SB45DEO, manufactured by Cognis Japan Ltd.

Fatty acid is glycerol and fatty acid triester of oleic acid or stearic acid

. SOY42, made by Nippon Oil Co., Ltd.

C ₁₄ fatty acids: C ₁₆ fatty acids: C ₁₈ fatty acids: C ₂₀ fatty acids (including both saturated and unsaturated fatty acids) contain approximately 0.2:11:88:0.8 by weight of glycerol and fatty acid triesters , weight average molecular weight: 880

. Three C2L oil fatty acid glycerides, manufactured by Nippon Oil Co., Ltd.

C ₈ fatty acid: C ₁₀ fatty acid: C ₁₂ fatty acid contains about 37:7:56 by weight of glycerol and fatty acid triester, weight average molecular weight: about 570

. Tri-CL oil fatty acid glyceride, manufactured by Nippon Oil Co., Ltd.

C ₈ fatty acid: C ₁₂ fatty acid contains about 44:56 by weight of glycerol and fatty acid triester, weight average molecular weight: about 570

. Panasate 810s, manufactured by Nippon Oil Corporation

C ₈ fatty acid: C ₁₀ fatty acid contains about 85:15 by weight of glycerol and fatty acid triester, weight average molecular weight: about 480

. Panasate 800, manufactured by Nippon Oil Corporation

Fatty acid is all octane acid (C ₈ ) glycerol and fatty acid triester, weight average molecular weight: about 470

. Panasate 800B, manufactured by Nippon Oil Corporation

The fatty acid is all 2-ethyl hexane acid (C ₈ ) glycerol and fatty acid triester, weight average molecular weight: about 470

. NA36, manufactured by Nippon Oil Co., Ltd.

C ₁₆ fatty acids: C ₁₈ fatty acids: C ₂₀ fatty acids (including both saturated and unsaturated fatty acids) contain about 5:92:3 by weight of glycerol and fatty acid triesters, weight average molecular weight: about 880

. Three coconut oil fatty acid glyceride, manufactured by Nippon Oil Co., Ltd.

C ₈ fatty acids: C ₁₀ fatty acids: C ₁₂ fatty acids: C ₁₄ fatty acids: C ₁₆ fatty acids (including both saturated and unsaturated fatty acids) contain a weight ratio of about 4:8:60:25:3 Glycerol and fatty acid triester, weight average molecular weight: 670

. Dioctyl octanoate, manufactured by Nippon Oil Co., Ltd.

Fatty acid is a diester of glycerol and fatty acid of octanoic acid, weight average molecular weight: 340

[(a ₃ ) an ester of a chain hydrocarbon diol with at least one fatty acid]

. Kemubolu BL, made by Nippon Oil Co., Ltd.

Butyric acid (C ₁₂ ) monoester of butanediol, weight average molecular weight: about 270

. Kemubolu BS, manufactured by Nippon Oil Co., Ltd.

Octadecanoic acid (C ₁₈ ) monoester of butanediol, weight average molecular weight: about 350

. UNISTAR H-208BRS, manufactured by Nippon Oil Co., Ltd.

Diethyl 2-ethylhexane acid neopentyl glycol, weight average molecular weight: about 360

[(c ₂ ) an ester of a chain hydrocarbon tricarboxylic acid having three carboxyl groups, a hydroxy acid, an alkoxy acid or a side acid and at least one aliphatic monohydric alcohol]

. O-acetyl tributyl tributyl citrate, manufactured by Tokyo Chemical Industry Co., Ltd.

Weight average molecular weight: about 400

[(c ₃ ) an ester of a chain hydrocarbon dicarboxylic acid having two carboxyl groups, a hydroxy acid, an alkoxy acid or a pendant acid and at least one aliphatic monohydric alcohol]

. Dioctyl adipate, manufactured by Wako Pure Chemical Industries

Weight average molecular weight: about 380

[(d ₃ ) ester of fatty acid with aliphatic monohydric alcohol]

. At Retru WE20, Nippon Oil Co., Ltd.

Ester of dodecanoic acid (C ₁₂ ) and dodecyl alcohol (C ₁₂ ), weight average molecular weight: about 360

. At Leitru WE40, made by Nippon Oil Co., Ltd.

Ester of tetradecanoic acid (C ₁₄ ) and dodecyl alcohol (C ₁₂ ), weight average molecular weight: about 390

[(e ₁ ) polyoxygenated C _2-6 alkanediol]

. UNIOL D-1000, manufactured by Nippon Oil Co., Ltd.

Polypropylene glycol, weight average molecular weight: about 1000

. UNIOL D-1200, manufactured by Nippon Oil Co., Ltd.

Polypropylene glycol, weight average molecular weight: about 1200

. UNIOL D-3000, manufactured by Nippon Oil Co., Ltd.

Polypropylene glycol, weight average molecular weight: about 3000

. UNIOL D-4000, manufactured by Nippon Oil Co., Ltd.

Polypropylene glycol, weight average molecular weight: about 4000

. UNIOL PB500, manufactured by Nippon Oil Co., Ltd.

Polytetramethylene glycol, weight average molecular weight: about 500

. UNIOL PB700, manufactured by Nippon Oil Co., Ltd.

Polyoxybutylene polyoxypropylene glycol, weight average molecular weight: about 700

. UNIOL PB1000R, manufactured by Nippon Oil Co., Ltd.

Polytetramethylene glycol, weight average molecular weight: about 1000

[(e ₂ ) an ester of polyoxygenated C _2-6 alkanediol with at least one fatty acid]

. WILBRIDE cp9, manufactured by Nippon Oil Co., Ltd.

a compound in which an OH group at both ends of polytetramethylene glycol is esterified with palmitic acid (C ₁₆ ), weight average molecular weight: about 1150

[(e ₃ ) polyoxygenated C _2-6 alkanediol and at least one fatty acid ether]

. UNILUBE MS-70K, manufactured by Nippon Oil Co., Ltd.

Stearic acid decyl ether of polypropylene glycol, repeating unit of about 15, weight average molecular weight: about 1140

[(e ₅ ) polyoxygenated C _2-6 alkanediol and chain hydrocarbon tetraol, chain hydrocarbon triol, or ether of chain hydrocarbon diol]

. UNILUBE 5TP-300KB

Polyoxyethylene polyoxypropylene pentaerythritol ether formed by pentaerythritol 1 molar addition of ethylene oxide 5 moles and propylene oxide 65 moles, weight average molecular weight: 4130

. UNIOL TG-3000, manufactured by Nippon Oil Co., Ltd.

Glyceryl ether of polypropylene glycol, about 16 repeating units, weight average molecular weight: about 3000

. UNIOL TG-4000, manufactured by Nippon Oil Co., Ltd.

Glyceryl ether of polypropylene glycol, about 16 repeating units, weight average molecular weight: about 4000

[(f ₁ )chain alkanes]

. PARLEAM6, manufactured by Nippon Oil Co., Ltd.

a branched chain hydrocarbon produced by copolymerizing a flow of isoparaffin, isobutylene and n-butene, followed by addition of hydrogen, a degree of polymerization of from about 5 to about 10, and a weight average molecular weight of about 330.

[other materials]

. NA50, manufactured by Nippon Oil Co., Ltd.

Adding hydrogen to NA36, reducing the double bond ratio of glycerol and fatty acid from the unsaturated fatty acid of the raw material, weight average molecular weight: about 880

. (octanoic acid/capric acid) monoglyceride, manufactured by Nippon Oil Co., Ltd.

Octanoic acid (C ₈ ) and decanoic acid (C ₁₀ ) contain a monoester of glycerol and fatty acid in a weight ratio of about 85:15, weight average molecular weight: about 220

. Monomuls 90-L2 lauric acid monoglyceride, manufactured by Cognis Japan Ltd.

. Isopropyl citrate, manufactured by Tokyo Chemical Industry Co., Ltd.

Weight average molecular weight: about 230

. Diisostearyl malate

Weight average molecular weight: about 640

. UNIOL D-400, manufactured by Nippon Oil Co., Ltd.

Polypropylene glycol, weight average molecular weight: about 400

. PEG1500, made by Nippon Oil Co., Ltd.

Polyethylene glycol, weight average molecular weight: about 1500 ~ about 1600

. NONION S-6, manufactured by Nippon Oil Co., Ltd.

Polyoxyethylene monostearate, about 7 repeat units, weight average molecular weight: about 880

. WILBRIDE s753, manufactured by Nippon Oil Co., Ltd.

Polyoxyethylene polyoxypropylene polyoxybutylene glycerol, weight average molecular weight: about 960

. UNIOL TG-330, manufactured by Nippon Oil Co., Ltd.

Glyceryl ether of polypropylene glycol, repeating unit of about 6, weight average molecular weight: about 330

. UNIOL TG-1000, manufactured by Nippon Oil Co., Ltd.

Glyceryl ether of polypropylene glycol, about 16 repeating units, weight average molecular weight: about 1000

. UNILUBE DGP-700, manufactured by Nippon Oil Co., Ltd.

Diglyceryl ether of polypropylene glycol, repeating unit of about 9, weight average molecular weight: about 700

. UNIOX HC60, manufactured by Nippon Oil Co., Ltd.

Polyoxyethylene hardened castor oil, weight average molecular weight: about 3570

. Vaseline, manufactured by Cognis Japan Ltd.

Hydrocarbon, semi-solid from petroleum

The IOB of the above sample, the melting point and the water solubility are shown in Table 2 below.

Further, the water solubility was measured by adding 20.0 g to 100 g of demineralized water according to the above method, and the sample dissolved after 24 hours was evaluated as "20 g <", and in 100 g of demineralized water, the sample dissolved in 0.05 g but not dissolved in 1.00 g was evaluated as 0.05~1.00g.

Further, regarding the melting point, "<45" has a melting point of less than 45 °C.

The skin contact surface of the top sheet of the above sanitary napkin is coated with the above blood modifying agent. Each blood modifying agent and blood modifying agent are directly used at room temperature, and the blood modifying agent is heated to a melting point of +20 ° C when the room temperature is solid, and then, using a control seam HMA gun, each The blood modifying agent was micronized, and the entire skin contact surface of the top sheet was applied so that the basis weight was about 5 g/m ² .

Fig. 12 is an electron micrograph of the skin contact surface of the top sheet in the physiological sanitary napkin (No. 2-5) containing the top C 3L oil fatty acid glyceride. As can be understood from Fig. 12, the tri-C2L oil fatty acid glyceride adhered to the surface of the fiber in the form of fine particles.

According to the above operation method, the rewet rate and the moving speed of the absorber are measured. Knot The results are shown in Table 2 below.

〔experiment method〕

On the top sheet containing each blood modifying agent, an open acrylic plate (200 mm × 100 mm, 125 g, with a hole of 40 mm × 10 mm in the center) was placed, and the horse was EDTA blood (37 ± 1 ° C) from the above hole. In order to prevent coagulation, 3 g of ethylenediaminetetraacetic acid (hereinafter referred to as "EDTA") was added to the blood, and the mixture was dropped using a pipette (first time). After 1 minute, the horse was EDTA at 37±1 °C. 3 g of blood was dropped from the acupuncture point of the acrylic plate and the pipette was again dropped (the second time).

Immediately after the dropping of the second blood, the acrylic plate was removed, and 10 pieces of filter paper (ADVANTEC Toyo Co., Ltd. qualitative filter paper No. 2, 50 mm × 35 mm) were placed in the place where the blood was dropped, and the pressure was 30 g/ Place the weight in the way of cm ² . After 1 minute, the filter paper was taken out, and the "reverse bleed rate" was calculated by the following formula.

Infiltration rate (%) = 100 × (quality of filter paper after test - original filter paper quality) / 6

Further, in addition to the evaluation of the rewet rate, the time during which the blood is moved from the top sheet to the absorber after the second blood drop is measured is the "absorbent moving speed". The moving speed of the absorbent body refers to the time until the top sheet is put into the blood until the red color of the blood is not visible on the surface of the top sheet and inside.

The results of the rewet ratio and the moving speed of the absorbent body are shown in Table 2 below.

Next, the top sheet after the test of the moving speed of the absorber The whiteness of the skin contact surface was visually evaluated using the following criteria.

◎: The red color of the blood hardly remains, and it is impossible to distinguish between the place where the blood exists and the place where it does not exist.

○: Although there are some residues in the red color of the blood, it is difficult to distinguish between the place where the blood exists and the place where it does not exist.

△: There are some residues in the red color of the blood, and the place where the blood exists is known.

×: The red color of the blood directly remains

The results are shown in Table 2 below.

In the case of no blood modifying agent, the rate of reversion is 22.7%, and the absorption speed of the absorbent body exceeds 60 seconds, and the glycerin and the fatty acid triester have a back bleed rate of 7.0% or less and the absorbent moving speed of 8 seconds or less, so that the absorption performance is greatly improved. However, in the triester of glycerin and fatty acid, at the NA50 having a melting point exceeding 45 ° C, no significant improvement in the absorption performance was observed.

Similarly, it can be seen that it has a range of about 0.00 to about 0.60. IOB, a melting point of about 45 ° C or less, and a water modifying agent having a water solubility of about 0.00 to about 0.05 g for 100 g of water at 25 ° C, the absorption performance is greatly improved.

[Example 2]

Regarding the various blood types of animals, the rate of rewet is evaluated according to the above operation method. The blood that can be used in the experiment is as follows.

[animal species]

(1 person

(2) Horse

(3) sheep

[blood type]

. Defibration: After taking blood, stirring with a glass bead in an Erlenmeyer flask for about 5 minutes

. EDTA blood: Add 12% EDTA to venous blood 65mL. 2K physiological saline solution 0.5mL

[segmentation]

Serum or plasma: each defibrinated blood or EDTA blood was centrifuged at room temperature for about 10 minutes at room temperature for 10 minutes.

Blood cells: The serum is removed from the blood, and the residue is washed twice with phosphate buffered physiological saline (PBS), followed by phosphate buffered physiological saline solution containing serum.

An absorbent article was produced in the same manner as in Example 2 except that the trisodium C2L oil fatty acid glyceride was applied so that the basis weight was about 5 g/m ² , and the rewet ratio was evaluated for each of the above blood. Each blood was measured three times, and the average value was used.

The results are shown in Table 3 below.

The same tendency as the horse EDTA blood obtained in Example 2 And the blood of the sheep is also available. Also, the same tendency was observed in defibrinated blood and EDTA blood.

[Example 3] [Evaluation of blood retention]

The blood retention in the top sheet containing the blood modifying agent and the top sheet containing no blood modifying agent was evaluated.

〔experiment method〕

(1) In the skin contact surface of the top sheet formed by hot air non-woven fabric (composite fiber composed of polyester and polyethylene terephthalate, basis weight: 35 g/m ² ), three C2L oil fatty acid glyceride was used. The control joint HMA gun was micronized and applied so that the basis weight became about 5 g/m ² . Further, for comparison, those who do not apply the tri-C2L oil fatty acid glyceride are also prepared. Next, both the top sheet coated with the tri-C2L oil fatty acid glyceride and the uncoated top sheet were cut to a size of 0.2 g, and the mass (a) of the sterile cell filtration cap tube + top sheet was correctly determined.

(2) Add about 2 mL of horse EDTA blood from the skin contact surface side Add and let stand for 1 minute.

(3) The sterile cell filtration cap tube was placed in a centrifuge tube, and subjected to low-speed centrifugation to remove excess horse EDTA blood.

(4) Determine the weight (b) of the top sheet containing the sterile cell filter cap + horse EDTA blood.

(5) The initial absorption amount (g) per 1 g of the top sheet was calculated according to the following formula.

Initial absorption = [weight (b) - weight (a)] / 0.2

(6) The sterile cell filtration cap tube was further placed in a centrifuge tube, and centrifuged at about 1200 G for 1 minute at room temperature.

(7) Determination of sterile cell filter cap tube + horse EDTA The weight of the top sheet of blood (c).

(8) The amount of absorption (g) per 1 g of the top sheet after the test was calculated according to the following formula.

Absorption after test = [weight (c) - weight (a)] / 0.2

(9) The blood retention rate (%) was calculated according to the following formula.

Blood retention rate (%) = 100 × absorption after test / initial absorption Further, the measurement was carried out three times, and the average value thereof was used.

The results are shown in Table 4 below.

Implied blood retention of the top sheet containing the blood modifying agent Low, after absorbing blood, it can move quickly to the absorber.

[Example 4] [viscosity of blood containing blood modifying agent]

The viscosity of blood containing a blood modifying agent was measured using a Rheometric Expansion System ARES (Rheometric Scientific, Inc). The mass% of Panasate 810s was added to the horse's fiber, and the sample was gently stirred to form a sample. The sample was placed in a parallel plate having a diameter of 50 mm, and the gap was 100 μm, and the viscosity was measured at 37 ± 0.5 °C. Because of the parallel plate, although the uniform shear rate was not applied to the sample, the average shear rate indicated by the machine was 10 s ^-1 .

Viscosity of horse defibrinated blood containing 2% by mass of Panasate 810s It is 5.9mPa. S, on the other hand, the viscosity of the horse hair fiber without blood modifying agent is 50.4mPa. s. Therefore, it was found that the horse defibrinated blood containing 2% by mass of Panasete 810s decreased by about 90% in comparison with the case where the blood modifying agent was not contained.

The blood is known to contain components such as blood cells, and has the property of shaking. However, it is considered that the blood modifying agent of the present invention can lower the viscosity of blood in a low viscosity domain. It is believed that by reducing the viscosity of the blood, the absorbed menstrual blood can be quickly moved from the top sheet to the absorber.

[Example 5] [Micrograph of blood containing blood modifying agent]

The menstrual blood of the healthy volunteers was collected on the wrap film, and Panastate 810s dispersed in 10 times by mass of phosphate buffered physiological saline was added in such a manner that the concentration of Panaseate 810s was 1% by mass. The menstrual blood was dripped onto the slide glass, and the coverslip was covered, and the state of the red blood cells was observed with an optical microscope. The photomicrograph of the menstrual blood containing no blood modifying agent is shown in Fig. 13(a), and the photomicrograph of the menstrual blood containing Panasate 810s is shown in Fig. 13(b).

As can be seen from Fig. 13, although in the menstrual blood containing no blood modifying agent, A collection block in which red blood cells are continuously arranged, etc., but in menstrual blood containing Panasate 810s, the red blood cells are stably dispersed. Therefore, it is suggested that the blood modifying agent has a function of calming red blood cells in the blood.

[Example 6] [Surface tension of blood containing blood modifying agent]

The surface tension of the blood containing the blood modifying agent was measured by a drip method using a contact angle meter Drop Master 500 manufactured by Kyowa Interface Science Co., Ltd. The surface tension is applied to the sheep defibrinated blood, and a specific amount of the blood modifying agent is added and measured after shaking sufficiently.

The measurement was automatically performed by a machine, and the density γ was obtained by the following equation (see FIG. 14 for reference).

γ=g×ρ×(de) ² ×1/H

g: gravity constant

1/H: correction term determined by ds/de

ρ: density

De: maximum diameter

Ds: the diameter of the position where only the de is raised by the drop end

The density ρ is measured according to the vibration density test method of "Density test method and density, mass and capacity conversion table" of JIS K 2249-1995, and is measured at the temperature shown in Table 5 below.

The measurement was performed using DA-505 of Kyoto Electronics Industry Co., Ltd.

The results are shown in Table 5.

As can be seen from Table 5, the blood modifying agent has a water solubility of about 0.00 to about 0.05 g per 100 g of water at 25 ° C, and the solubility in water is extremely low, but the surface tension of blood can be lowered.

It is believed that the absorbed blood is not retained by lowering the surface tension of the blood. Between the fibers of the top sheet, it can move quickly to the absorber.

Claims (14)

An absorbent article comprising a top sheet, a back sheet, and an absorbent body provided between the top sheet and the back sheet, wherein the top sheet is formed in a liquid supply region for receiving liquid supply. a stretchable region of the stretchable snake abdomen and a liquid permeable sheet surrounding the flexible region surrounding the stretchable region, wherein the liquid permeable sheet is stretched once in a second extension of the snake belly, and the stretchable region It is provided in such a manner that a raised portion of the bulge is formed in the thickness direction of the absorbent article. The absorbent article according to claim 1, wherein the top sheet is a plurality of stretchable regions having an extensible snake abdomen formed in the liquid supply region, and a flexible region surrounding each stretch region. In the liquid permeable sheet, the liquid permeable sheet is stretched once in a stretched manner in the bellows of each stretchable region, and each stretchable region is provided so as to form a raised ridge in the thickness direction of the absorbent article. The absorbent article according to claim 2, wherein the flexible region is formed in a mesh shape, and the stretchable region is formed inside each mesh. The absorbent article according to claim 3, wherein the flexible region has a substantially linear first region extending in a direction intersecting the longitudinal direction of the liquid permeable sheet and arranged in parallel. The direction intersecting with the first region is extended and arranged in parallel and arranged in parallel The second area is slightly linear. The absorbent article according to any one of claims 1 to 4, wherein the abdomen is extended in the longitudinal direction of the liquid permeable sheet, and is arranged side by side in the width direction of the liquid permeable sheet, and has the aforementioned The cross section in the width direction is a wavy mountain fold and a valley fold. The absorbent article according to any one of claims 1 to 4, wherein the liquid permeable sheet is provided such that one of the absorbers is filled in the inside of the raised portion. The absorbent article according to claim 6, wherein the liquid permeable sheet is convexly deformed by the liquid supply region, and the absorbent body is elastically restored by the flexible region due to the convex deformation. a portion of the absorbent body that is compressed by the elastic restoring force of the flexible region as compared with a portion of the absorbent body that is filled in the interior of the raised portion More high density. The absorbent article according to any one of claims 1 to 4, wherein a liquid permeation hole is formed in the stretchable region, and a liquid permeation hole is not formed in the flexible region. The absorbent article according to any one of claims 1 to 4, wherein a compression groove is formed in a peripheral portion of the liquid supply region. The absorbent article according to any one of claims 1 to 4, wherein the top sheet contains an IOB of 0.00 to 0.60, a melting point of 45 ° C or less, and a water solubility of 0.00 to 0.05 g for 100 g of water at 25 ° C. Blood modifier. The absorbent article according to claim 10, wherein the blood modifying agent is composed of (i) to (iii): (i) hydrocarbon; (ii) having (ii-1) hydrocarbon portion, and (ii) -2) a compound of one or more of the same or different groups selected from the group consisting of a carbonyl group (-CO-) and an oxy group (-O-) interposed between the CC single bonds of the aforementioned hydrocarbon moiety; and (iii) a one selected from the group consisting of a carbonyl group (-CO-) and an oxy group (-O-) interposed between (iii-1) a hydrocarbon moiety and (iii-2) a CC single bond of the aforementioned hydrocarbon moiety a plurality of identical or different groups, one or a plurality of identical or different selected from the group consisting of (iii-3) a carboxyl group (-COOH) and a hydroxyl group (-OH) substituted for a hydrogen atom of the aforementioned hydrocarbon moiety In the compound of (ii) or (iii), when two or more oxy groups are inserted, each oxy group is not adjacent. The absorbent article according to claim 10, wherein the blood modifying agent is (i') to (iii'): (i') hydrocarbon; (ii') has (ii'-1) hydrocarbon portion And (ii'-2) a carbonyl bond (-CO-), an ester bond (-COO-), a carbonate bond (-OCOO-), and an ether bond inserted between the CC single bonds of the aforementioned hydrocarbon moiety (-O-) one or more of the same or different bonded compounds selected in the group; and (iii') having (iii'-1) a hydrocarbon moiety, and (iii'-2) in the foregoing Carbon bond (-CO-), ester bond (- inserted between CC single bonds of hydrocarbon moiety One or a plurality of identical or different linkages selected from the group consisting of COO-), carbonate linkage (-OCOO-), and ether linkage (-O-), and (iii'-3) are substituted for the foregoing a group of one or more compounds of the same or different groups selected from the group consisting of a carboxyl group (-COOH) of a hydrogen atom of a hydrocarbon moiety and a hydroxyl group (-OH); and a combination of any combination thereof, Here, in the compound of (ii') or (iii'), when two or more identical or different bonds are inserted, the bonds are not adjacent. The absorbent article according to claim 10, wherein the blood modifying agent has a chain hydrocarbon portion and a hydrogen substituted for the chain hydrocarbon portion (A) to (F): (A) (A1) a compound having 2 to 4 hydroxyl groups of an atom and (A2) an ester having a chain hydrocarbon moiety and a compound which substitutes one carboxyl group of a hydrogen atom of the chain hydrocarbon moiety; (B) (B1) has a chain hydrocarbon moiety; a compound of (2) a compound having 2 to 4 hydroxyl groups which replaces the hydrogen atom of the chain hydrocarbon moiety; and (B2) a compound having a chain hydrocarbon moiety and a hydroxyl group which replaces the hydrogen atom of the chain hydrocarbon moiety; (C1) a carboxylic acid, a hydroxy acid, an alkoxy acid or a oxo acid having a chain hydrocarbon moiety and a hydrogen atom of 2 to 4 groups which replaces the hydrogen atom of the chain hydrocarbon moiety, and (C2) having a chain hydrocarbon moiety, and An ester of a compound which replaces one hydroxyl group of a hydrogen atom of the aforementioned chain hydrocarbon moiety; (D) an ether bond (-O-) having a chain hydrocarbon moiety interposed between a CC single bond of the aforementioned chain hydrocarbon moiety, a carbonyl bond a compound selected from the group consisting of a knot (-CO-), an ester bond (-COO-), and a carbonate bond (-OCOO-); (E) a polyoxygenated C _2-6 alkane Alcohol, or its alkyl ester or The alkyl ether; and (F) chain hydrocarbon; and any combination of these are selected in the group. The absorbent article according to claim 10, wherein the blood modifying agent is an ester of (a ₁ ) chain hydrocarbon tetraol and at least one fatty acid, (a ₂ ) chain hydrocarbon triol and at least one fatty acid Ester, (a ₃ ) chain hydrocarbon diol and at least one fatty acid ester, (b ₁ ) chain hydrocarbon tetraol and at least one aliphatic monohydric alcohol ether, (b ₂ ) chain hydrocarbon triol And an ether of at least one aliphatic monohydric alcohol, (b ₃ ) a chain hydrocarbon diol and at least one aliphatic monohydric alcohol, (c ₁ ) a chain hydrocarbon tetracarboxylic acid having four carboxyl groups, a hydroxyl group An acid, alkoxy acid or an acid ester of a side acid with at least one aliphatic monohydric alcohol, (c ₂ ) a chain hydrocarbon tricarboxylic acid having three carboxyl groups, a hydroxy acid, an alkoxy acid or a side acid An ester of at least one aliphatic monohydric alcohol, (c ₃ ) a chain hydrocarbon dicarboxylic acid having two carboxyl groups, a hydroxy acid, an alkoxy acid or an ester of a side acid and at least one aliphatic monohydric alcohol; (d ₁ ) an aliphatic monohydric alcohol and an aliphatic monohydric alcohol ether, (d ₂ ) dialkyl ketone, (d ₃ ) fatty acid and an aliphatic monohydric alcohol ester, (d ₄ ) dialkyl carbonate And (e ₁ ) polyoxy C _2-6 alkanediol, (e ₂ ) polyoxygenated C _2-6 alkanediol and at least one fatty acid ester , (e ₃ ) polyoxy C _2-6 alkanediol and at least one aliphatic monohydric alcohol ether, (e ₄ ) polyoxygenated C _2-6 alkanediol and chain hydrocarbon tetracarboxylic acid, chain hydrocarbon An ester of a tricarboxylic acid or a chain hydrocarbon dicarboxylic acid, (e ₅ ) a polyoxy C _2-6 alkanediol and a chain hydrocarbon tetraol, a chain hydrocarbon triol, or an ether of a chain hydrocarbon diol, and (f ₁ ) a chain alkane, and any combination thereof, selected in the group.