TWI458478B - 用於代謝症候群與第２型糖尿病的反式氯米芬 - Google Patents

用於代謝症候群與第２型糖尿病的反式氯米芬 Download PDF

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Publication number
TWI458478B
TWI458478B TW098137209A TW98137209A TWI458478B TW I458478 B TWI458478 B TW I458478B TW 098137209 A TW098137209 A TW 098137209A TW 98137209 A TW98137209 A TW 98137209A TW I458478 B TWI458478 B TW I458478B
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TW
Taiwan
Prior art keywords
clomiphene
trans
individual
levels
serum
Prior art date
Application number
TW098137209A
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English (en)
Chinese (zh)
Other versions
TW201031400A (en
Inventor
As Andre Van
Original Assignee
Repros Therapeutics Inc
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41404260&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TWI458478(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Repros Therapeutics Inc filed Critical Repros Therapeutics Inc
Publication of TW201031400A publication Critical patent/TW201031400A/zh
Application granted granted Critical
Publication of TWI458478B publication Critical patent/TWI458478B/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW098137209A 2008-11-07 2009-11-03 用於代謝症候群與第２型糖尿病的反式氯米芬 TWI458478B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11245808P 2008-11-07 2008-11-07

Publications (2)

Publication Number Publication Date
TW201031400A TW201031400A (en) 2010-09-01
TWI458478B true TWI458478B (zh) 2014-11-01

Family

ID=41404260

Family Applications (2)

Application Number Title Priority Date Filing Date
TW098137209A TWI458478B (zh) 2008-11-07 2009-11-03 用於代謝症候群與第２型糖尿病的反式氯米芬
TW103133928A TW201500041A (zh) 2008-11-07 2009-11-03 用於代謝症候群與第２型糖尿病的反式氯米芬

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW103133928A TW201500041A (zh) 2008-11-07 2009-11-03 用於代謝症候群與第２型糖尿病的反式氯米芬

Country Status (4)

Country Link
AR (1) AR074302A1 (es)
CL (1) CL2009002036A1 (es)
TW (2) TWI458478B (es)
WO (1) WO2010054248A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2312593T3 (es) 2001-07-09 2009-03-01 Repros Therapeutics Inc. Procedimientos y materiales para el tratamiento de la deficiencia de testosterona en hombres.
UA113291C2 (xx) 2011-08-04 2017-01-10 Метаболіти транскломіфену і їх застосування
JP2015506988A (ja) * 2012-02-14 2015-03-05 レプロス セラピューティクス インコーポレイティド 半減期の短い選択的エストロゲン受容体モジュレーターおよびその使用
UA113324C2 (xx) * 2012-08-21 2017-01-10 Склади транс-кломіфену та їх застосування
CA2889770A1 (en) * 2012-11-02 2014-05-08 Repros Therapeutics Inc. Trans-clomiphene for use in cancer therapy
WO2017147264A1 (en) * 2016-02-25 2017-08-31 Aspen Park Pharmaceuticals, Inc. Oral dosage form of both clomiphene isomers and method of using same to treat secondary hypogonadism
US10364212B2 (en) 2016-04-22 2019-07-30 F.I.S.—Fabbrica Italiana Sintetici S.p.A. Process for the preparation of enclomiphene citrate having needle shaped crystal habit

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7067557B2 (en) * 2000-05-26 2006-06-27 Harry Fisch Methods of treating androgen deficiency in men using selective antiestrogens

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3071412A1 (en) * 2005-03-22 2006-09-28 Allergan Pharmaceuticals International Limited Dosing regimes for trans-clomiphene
EP1829534A1 (en) * 2006-03-02 2007-09-05 Laboratorios Del Dr. Esteve, S.A. Use of compounds binding to the sigma receptor for the treatment of metabolic syndrome
MX2010004195A (es) * 2007-10-16 2010-06-02 Repros Therapeutics Inc Trans-clomifeno para el sindrome metabolico.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7067557B2 (en) * 2000-05-26 2006-06-27 Harry Fisch Methods of treating androgen deficiency in men using selective antiestrogens

Also Published As

Publication number Publication date
WO2010054248A1 (en) 2010-05-14
TW201031400A (en) 2010-09-01
AR074302A1 (es) 2011-01-05
TW201500041A (zh) 2015-01-01
CL2009002036A1 (es) 2010-02-05

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