TWI438190B - ３－（苯氧基苯基甲基）吡咯啶化合物 - Google Patents

Info

Publication number

TWI438190B

TWI438190B TW098124917A TW98124917A TWI438190B TW I438190 B TWI438190 B TW I438190B TW 098124917 A TW098124917 A TW 098124917A TW 98124917 A TW98124917 A TW 98124917A TW I438190 B TWI438190 B TW I438190B

Authority

TW

Taiwan

Prior art keywords

alkyl

halo

compound

optionally substituted

independently

Prior art date

2008-07-24

Links

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• DZXJNYJKRVCFEZ-UHFFFAOYSA-N 3-[phenoxy(phenyl)methyl]pyrrolidine Chemical class C1NCCC1C(C=1C=CC=CC=1)OC1=CC=CC=C1 DZXJNYJKRVCFEZ-UHFFFAOYSA-N 0.000 title description 3
• 150000001875 compounds Chemical class 0.000 claims description 518
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• 125000005843 halogen group Chemical group 0.000 claims description 302
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• -1 -C 0-6 alkyl-OH Chemical group 0.000 claims description 81
• 125000001153 fluoro group Chemical group F* 0.000 claims description 69
• 150000003839 salts Chemical class 0.000 claims description 55
• 208000002193 Pain Diseases 0.000 claims description 49
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• 125000002947 alkylene group Chemical group 0.000 claims description 17
• 229940124597 therapeutic agent Drugs 0.000 claims description 16
• 125000005037 alkyl phenyl group Chemical group 0.000 claims description 13
• 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 13
• 239000003937 drug carrier Substances 0.000 claims description 13
• 150000001335 aliphatic alkanes Chemical class 0.000 claims description 11
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