TWI393559B - Blood-collecting initial flow removing bag, blood-collecting initial flow removing set - Google Patents

Description

Blood collection first stream removal bag, blood collection primary flow removal group and blood bag

The present invention relates to a blood collection primary flow removal bag and a blood collection primary flow removal group which can take initial blood and simultaneously perform blood for examination at the time of blood collection operation.

In a blood collection operation for blood transfusion in a medical institution or a blood center, the following operations are generally performed: when the blood taken from the blood collection needle is introduced into the blood bag, the puncture position of the blood donor is sufficiently disinfected by alcohol or the like to prevent blood collection. The pollution of the blood. However, even if the disinfection is carried out with care and caution, bacteria (inherent bacteria) such as Staphylococcus epidermidis or acne bacteria present in the skin or under the skin may be mixed into the blood taken. The reason for this is considered to be that the puncture needle passes through the skin line in which the bacteria are present, or is mixed with the small skin piece attached to the bacteria cut by the puncture needle.

These bacteria are also proliferated during storage in the blood bag depending on the type of the bacteria. If the bacteria are not used for blood transfusion, the blood transfused patients may cause infectious diseases, etc., which may become a serious situation. Hey.

It is well known that the contaminated blood caused by such bacteria is mixed into the initial flow of blood taken. In this regard, in particular, the device for removing blood from the initial flow at the time of blood collection has completed various proposals to prevent bacterial contamination of the blood taken.

Patent Document 1 describes a sampling system that can take blood for examination while maintaining the sterility between the blood donor and the collection container at the beginning of the blood donation sequence.

The discharge pipe 43 is formed to extend toward the substantially circular inner chamber 54 to which the holder 68 for holding the liquid sampling bottle 70 is connected to the outlet port 50 that is connected to the discharge pipe 43. Further, in the internal chamber 54, the blood inside the internal chamber 54 is sucked from the container 42 to the sampling bottle by the discharge pipe 43 extending to the vicinity of the inlet port 46, and the air cannot enter the sampling bottle. .

Patent Document 2 to Patent Document 5 describe a container-connected body that can take the initial flow of blood collected, and describes the accuracy of the bacteria test for blood-sucking blood and the workability during the blood test, and can be improved. The safety of blood collection.

Specifically, for example, in Patent Document 4, a tube 91 is connected to a branch joint 92 formed in a tube 15 having a blood collection bag 10 connected to the blood collection bag 10 and a blood collection needle 152 connected by a tube 15, and a tube 91 is attached thereto. A bag 20 for temporarily storing blood is connected to the part. In the bag 20, a tube 96 having a sampling port 71 formed therein is connected to the front end. The blood collection device 1 can perform the bacteria inspection by easily and safely introducing the taken-out blood to the blood collection tube connected to the sampling port 71, so that the reliability of the bacteria test is high.

Further, Patent Document 6 describes a blood bag in which the storage chamber 42 of the blood component and the outflow path 41 of the blood component lower layer are formed in the blood collection bag 32 by the partition portion 40. The blocking members 10, 20, and 43 are attached near the upstream of the passage 39 formed by the partition portion 40.

By dividing the blood bag into the blood bag by the partition portion 40, and separating the upper layer, the intermediate layer, and the lower layer by the centrifugal separation process, the intermediate layer is retained in the blood collection bag 32 while the intermediate layer is maintained in a state in which the blood components are not mixed with each other. The upper flow outlet 39a is separated and removed from the separation bag 33, and the lower layer breaks the clogging members 10, 20, and 43 and is separated and discharged to the discharge port 39b and the separation bag 34 via the outflow path 41 formed by the partition portion 40.

In the invention of Patent Document 1, when the blood in the container 42 is taken, it is difficult to take in the air by the discharge pipe 43 even if the sampling system is reversed, but it is not possible to prevent the air inside the discharge pipe 43 from being taken into the sampling bottle. Further, since the blood is taken in through the discharge tube 43, only a small amount of blood can be taken in the sample bottle, and the operation from the container 42 to the blood of the sample bottle cannot be quickly performed. Moreover, when blood in the container 42 is taken, there is a limit to the necessity of reversing the sampling system.

In the inventions of Patent Document 2 to Patent Document 5, it is possible to perform the removal of the primary blood and the sampling of the blood. However, in the configuration of the bag, the blood collection device is located at a low position when the blood is collected from the blood donor, so the operator must Sampling blood in a more stubborn position such as bending or squatting, especially in a narrow place such as a blood donation cart, it is very painful to perform the same work many times.

Further, the partition portion 40 formed in the bag 31 of Patent Document 6 is the outlet of the separated blood, and it is necessary to attach the blocking members 10, 20, and 43.

In view of the above prior art, the applicant of the present invention first proposed an invention relating to a blood collection primary flow removing bag as disclosed in Patent Document 7.

That is, the proposed invention provides a method in which an operator can quickly adopt a blood blood collection primary flow removing bag, a blood collection primary flow removing group, and a blood bag without using a relatively strong posture.

The invention relates to a blood collection primary flow removing bag for storing blood from a blood donor, which is a blood collection primary flow removing bag BA', BD: an inlet 23 for initial blood flow and an initial blood flow in the bag body 21. The outlet 24 forms the first partition portion P1, the second partition portion P2, and the third partition portion P3 inside the bag body 21, thereby dividing the inside of the bag body 21 into the blood storing portion S1 and the air storing portion S2, and forming a blood passage. When W1 and the air passage W2 store the primary blood in the empty bag body 21, the primary blood is stored in the blood storage unit S1 via the inlet 23 and the blood passage W1, and the air in the blood storage unit S1 is stored in the air storage unit S2. (Refer to Fig. 6 and Fig. 8).

The invention is effective in the following effects: (1) The operator does not need to adopt a relatively strong posture such as bending, and the blood can be quickly sampled by the blood collection first bag BA', BD; (2) The air passage W2 formed in the bag body 21 does not move to the blood storage portion S1 again when the air is rushed to the air storage portion S2 during the initial blood collection. Therefore, even when the blood is taken to the vacuum blood collection tube, even if the blood is collected The flow removing bag BA' and the BD are reversed, and the air is not taken in the vacuum blood collecting tube; and (3) the predetermined amount of blood to be taken can be easily determined in the blood collecting primary flow removing bag BA' and BD.

However, in the blood collection primary flow removing bag (BA', BD) described in Patent Document 7, the spacers (P1 to P3) are formed in the bag body 21, whereby the air storage portion S2 is formed, and thus the spacer is not formed ( Compared with the blood collection primary flow removing bag of P1 to P3), there is a problem that it takes time to collect blood (longer blood collection time). Here, the "blood collection time", in the blood collection preliminary flow removal bag BD in Patent Document 7, means that the blood flow is stuck in the blood storage portion S1 from the blood collection needle, and the blood reaches the upper opening portion O1. The time until the first drop of the blood falls into the air storage portion S2 (the time until the initial blood flow is completed).

In this way, if it takes time to collect blood from the initial blood, the working time of the blood collector becomes longer (low productivity), and the burden on the body of one of the donors is longer, so the blood collection time is longer. Both sides are better for a slightly shorter blood collection time.

[Previous Technical Literature] [Patent Literature]

[Patent Document 1] Japanese Patent Laid-Open Publication No. 2003-505185 ([Patent Application Scope], [0026], [0034])

[Patent Document 2] Japanese Patent Laid-Open No. Hei 10-84942 ( [Application Patent Area], Fig. 1)

[Patent Document 3] Japanese Patent Laid-Open No. Hei 11-197236 ([Application Patent Area], Fig. 1)

[Patent Document 4] Japanese Patent Laid-Open Publication No. 2001-17539 ([0085] to [0093], Fig. 1)

[Patent Document 5] Japanese Patent Laid-Open Publication No. 2005-279289 ([0037], Fig. 1)

[Patent Document 6] Patent No. 3179208 ([Patent No. 3], [0015], [0016], FIG. 5)

[Patent Document 7] Japanese Patent Laid-Open Publication No. 2008-131962 (Fig. 6, Fig. 8)

The subject to be solved by the present invention is:

The blood collection primary flow removing bag (BA', BD) described in Patent Document 7 exhibits various excellent effects, but forms a space portion (P1 to P3) in the bag body 21 to form an air storage portion S2. Therefore, it takes time to collect blood from the primary blood as compared with the blood collection primary flow removing bag in which the spacers (P1 to P3) are not formed.

An object of the present invention is to shorten the blood collection time of the primary blood even if the spacers (P1 to P3) are formed in the bag body 21.

Therefore, in order to solve the above problems, the inventors of the present invention have completed the following inventions in order to solve the above problems.

[1] According to the present invention, the following blood collection primary flow removing bags B and BB can be provided.

A blood collection primary flow removing bag (B, BB), which is a person who stores blood from a blood donor and is used for blood for examination thereafter; and is characterized in that: a bag body (21) for storing initial blood is provided. Forming an inlet (23) for the primary blood in the upper portion of the bag body (21), and forming an outlet (24) for the primary blood in the lower portion of the bag body (21), the bag body (21) having at least a zone The upper upper wall surface (UD, WD) and the side wall surface (SD) of the partition side, the inside of the bag body (21) is composed of a plurality of first partitions (P1), second spacers (P2), and third a spacer (P3) partitioned into a blood storage unit (S1) for storing blood and an air storage unit (S2) for storing air removed by the blood, wherein the first spacer (P1) is from the bag a partition wall is formed in a substantially oblique direction in a substantially oblique direction inside the main body (21), and the second partition portion (P2) forms a partition wall along a substantially longitudinal direction inside the bag body (21), and the third partition portion ( P3) forming a partition wall in a substantially oblique direction or a substantially lateral direction inside the bag body (21), and the first spacer (P1) is from the second The lower portion of the partition (P2) is continuously formed across the side wall surface (SD) of the bag body (21) on the side opposite to the second partition portion (P2), and the second partition portion (P2) is attached to The side portion of the first partition portion (P1) opposite to the side wall surface (SD) of the bag body (21) is continuously formed to stand in the upward direction, and the third partition portion (P3) is continuously formed. The second partition portion (P2) is formed between the upper wall surface (UD) of the bag body (21), and the air introduced into the air storage portion (S2) is formed at an upper portion of the second partition portion (P2). The inducing portion (R2) forms an inducing portion (R1) for introducing blood into the blood storing portion (S1) at a lower portion of the third spacer portion (P3), and the air inducing portion (R2) and the first portion 3, between the partitions (P3), an air passage (W2) for introducing air into the air storage portion (S2), a front end portion of the air inducing portion (R2) and an upper wall surface of the bag body (21) (WD) Between the third opening portion (O3) functioning as an inlet for introducing air into the air storage portion (S2), the third partition portion (P3) and the bag body (21) are formed. a blood passage (W1) for forming blood of the blood collected between the upper wall surfaces (UD), and formed between the blood inducing portion (R1) and the side wall surface (SD) of the bag body (21) The first opening portion (O1) functioning as an inlet port for blood to the blood storing portion (S1), the blood inducing portion (R1) and the second spacer portion (P2) in the third spacer portion (P3) a second opening portion (O2) having a function as an inlet to the air in the air storage portion (S2), wherein the blood passage (W1) is opened through the inlet (23) of the primary blood and the first opening a portion (O1) communicating with the blood storage portion (S1), wherein the air passage (W2) communicates with the blood storage portion (S1) via the second opening portion (O2), and passes through the third opening portion ( O3) is in communication with the air storage unit (S2), and has a first opening portion (O1) having a function as an inlet port for blood to the blood storage portion (S1), and having a function as the air storage portion (S2) The second opening portion (O2) functioning as the inlet of the air is interposed between the third partition portion (P3) The blood inducing portion (R1) is adjacent to each other; viewed from the left upper wall surface (UD) to the left side wall surface (SD) direction of the bag body (21) to the left upper wall surface of the bag body (21) ( The blood passage (W1) is formed by contacting UD) to the left side wall surface (SD), and the air passage is formed in a substantially central direction of the bag body (21) along the blood passage (W1) ( W2).

[2] Further, according to the present invention, there is provided a blood collection primary flow removing bag (B, BB) according to [1], wherein the first spacer portion (P1) and the second spacer portion (P2) are from the above One side of the bag body (21) is continuous in the direction of the upper direction and the inlet (23) of the primary blood flow through the substantially central direction, and is formed substantially Word shape.

[3] Further, according to the present invention, there is provided a blood collection primary flow removing bag (BB) according to [1] or [2], wherein the blood inducing portion (R1) is from the third spacer portion (P3) The extension is provided to the vicinity of the intersection of the side end portion of the first spacer portion (P1) and the lower end portion of the second spacer portion (P2).

[4] Further, according to the present invention, the blood collection primary flow removing bag (BB) according to any one of [1] to [3], wherein the second spacer (P3) and the blood are induced A first air passage (W2.1) is formed between the portions (R1), and a second air passage (W2.2) is formed between the air inducing portion (R2) and the third partition portion (P3). The first air passage (W2.1) and the second air passage (W2.2) have It functions as an exhaust flow path of the air introduced into the air storage unit (S2).

[5] Further, according to the present invention, there is provided a blood collection primary flow removing bag (B) according to [1] or [2], wherein the blood inducing portion (R1) faces the lower portion of the bag body (21), The end portion of the second spacer portion (P2) extends from the upper end portion of the second spacer portion (P2) to a position substantially 1/4 to 1/3 of the entire length of the second spacer portion (P2).

[6] Further, according to the present invention, the blood collection primary flow removing bag (B) according to any one of [1], [2], and [5], wherein the bag body (21) is formed in the bag body (21) The space (S) between the second spacer (P2) and the side wall surface (SD) of the bag body (21) has a blood inflow path as blood introduced into the blood storage unit (S1). And the function of introducing both of the exhaust flow paths of the air to the air storage unit (S2).

[7] Further, according to the present invention, the blood collection primary flow removing bag (B, BB) according to any one of [1] to [6], wherein the air passage (W2) is formed larger than the width of the air passage (W2) The width of the blood passage (W1) is 100 with respect to the width of the air passage (W2), and the width of the blood passage (W1) is 120 to 300.

[8] Further, according to the present invention, the blood collection primary flow removing bag (B, BB) according to any one of [1] to [7], wherein the inlet (23) of the primary blood is substantially At the center, the upper wall surface (UD) of the bag body (21) is formed so as to be inclined toward the inlet (23) of the primary blood, and the air inducing portion (R2) of the upper portion of the second spacer (P2) is Similarly, the upper wall surface (UD) of the bag body (21) is formed to be inclined toward the inlet (23) of the primary blood.

[9] Further, according to the present invention, the blood collection primary flow removing bag (B, BB) according to any one of [1] to [8], wherein the upper wall surface (UD) of the bag body (21) is provided The air inducing portion (R2) on the upper portion of the second partition portion (P2) is formed so as to be inclined substantially parallel to the inlet (23) direction of the primary blood.

[10] Further, according to the present invention, the blood collection primary flow removing bag (B, BB) according to any one of [1] to [9], wherein the initial blood is initially supplied from the bag body (21) When the inlet (23) of the upper first blood flow is introduced and stored in the empty blood storage portion (S1) of the bag body (21), the air in the blood storage portion (S1) is excluded by the blood taking. And stored in the air storage unit (S2) via the second opening unit (O2), the air passage (W2), and the third opening unit (O3).

[11] Further, according to the present invention, the blood collection primary flow removing bag (B, BB) according to any one of [1] to [10], wherein, from the blood storage portion (S1) to the above, When blood is accumulated in the third open unit (O3), it can be regarded as the prescribed amount of blood that can be taken.

[12] Further, according to the present invention, the following blood collection primary flow removal group can be provided.

A blood collection initial flow removal group (1), which is characterized by:

In the first blood collection bag (B, BB) of any one of [1] to [11], the blood outlet (24) of the first blood is removed, thereby forming a means for taking blood to the outer container.

[13] Further, according to the present invention, a blood bag (2) having an initial flow removing function, which is composed of a mother bag (4) for taking blood and a plurality of sub-bags (5, 6), is characterized in that: The primary blood introduction tube (T2) is connected to a branch tube (13a) disposed in the middle of the blood collection tube (T1) to which the blood collection needle (8) is connected upstream, and the blood collection initial flow removal group (1) is as follows [1] Connected to the downstream of the primary blood introduction tube (T2).

The blood collection primary flow removing bags B and BB of the present invention have the following effects.

In the present invention, the first to third spacers (P1, P2, P3) are formed in the bag body 21, and are viewed from the left upper wall surface UD of the bag body 21 to the left side wall surface SD (SDL) direction to be in contact with the bag body. The blood passage W1 is formed to contact the left upper wall surface UD of the 21 to the left side wall surface SD, and the air passage W2 is formed in the substantially central direction of the bag body 21 along the blood passage W1.

<1> As a result, in the blood collection primary flow removing bag B (FIG. 1), the space S is formed between the second partition portion P2 in the bag body 21 and the side wall surface SD of the bag body 21. The space S has both a function of (i) a blood inflow path of blood introduced into the blood storage unit S1, and (ii) an exhaust flow path of air introduced into the air storage unit S2. As a result, the length of the flow path of the combined blood flow path and the air flow path is substantially shortened. Therefore, the blood collection first flow in Patent Document 7 in which the partition portion (P1, P2, P3) is formed in the bag body 21 in the same manner. Compared with the bag (BA', BD), the blood collection time can be greatly shortened. In this sense, the space S is a space for forming an "integral flow path".

<2> On the other hand, in the blood collection first flow removing bag BB (FIG. 4), the blood storage portion S1 expands due to the inflow of blood, and the air passage W2 is easily expanded, and the air is easily and smoothly retained in the air storage portion S2. When the blood flows in, the blood collection time can be shortened because it becomes difficult to apply resistance.

<3> Further, in the blood collection first flow removing bags B and BB, the width of the blood passage W1 is formed larger than the width of the air passage W2, and as a result, the width (area) of the blood passage W1 in the bag body 21 is largely formed. Therefore, this can help shorten the blood collection time.

<4> Since the blood inflow flow path and the exhaust flow path have a larger area than the blood collection primary flow removing bag (BA', BD) in Patent Document 7, the blood is easily infiltrated and the air is easily discharged.

<5> The third opening portion O3 is disposed at the uppermost portion of the air storage portion S2, and during the reverse operation after blood collection [see FIG. 3(D)], the blood BL' flows into the air storage portion S2, and the air storage portion The air in S2 is pressed upwards, so that the backflow of air can be prevented when blood is collected by vacuum blood collection tubes. (The blood BL' in the air storage portion S2 prevents the air from flowing back)

Hereinafter, the present invention will be described in detail with reference to the drawings.

The blood collection primary flow removal group 1 of the present invention is formed as shown in Fig. 1, and is mainly formed by the blood collection primary flow removal bag B (or the blood collection primary flow removal bag BB of Fig. 4). Further, as shown in FIG. 2, the primary flow removal group 1 is a blood collection and storage system for a blood bag, that is, a blood bag 2 for collecting blood from a blood donor (donor) and storing it in blood for blood transfusion, The blood collection primary flow removal group 1 is loaded into a portion of the blood collection circuit and has an initial flow removal function.

(Pumplet first stream removal group 1)

First blood flow line for removing a group of the following operator: in other blood collection, separation and the major portion of blood taken, for example, about 10 to 30 ml of the initial portion of the donor's blood (First blood flow), which was taken The bag B is removed from the blood collection first, thereby preventing the incorporation of bacteria or the like which are present in the skin or subcutaneous portion of the needle puncture portion, and is also used for inspecting the blood for the blood flowing into the bag B.

The blood collection primary flow removing group 1 is composed of a blood collection primary flow removing bag B (or a bag BB) for storing an initial flow and a means for taking the stored blood (for example, a vacuum blood collection tube holder 22 to be described later). The primary flow removal group 1 is as shown in FIG. 1, and more specifically, as shown in FIG. 2, the blood collection and storage system for the blood bag 2 is connected to the branch pipe 13a disposed in the middle of the blood collection tube T1. The first flow is connected to the downstream (end) of the blood introduction tube T2 and used.

(Blood blood removal bag B, BB)

The blood collection first flow removal bags B and BB are mainly the ones which constitute the blood collection primary flow removal group 1 of the present invention, and are used for storing the blood from the blood donors and performing the blood for inspection thereafter.

As shown in FIG. 1 and FIG. 4, the primary flow removing bags B and BB respectively include a bag body 21 for storing primary blood, and a top portion of the bag body 21 is formed to take the taken blood into the bag body. The inlet 23 for the initial blood flow in 21 forms an outlet 24 for taking out the blood taken at the lower portion of the bag body 21. Further, the bag body 21 includes at least a side portion (or a side wall surface SD) that partitions an upper upper wall surface UD and a partitioned side surface.

A spacer is formed inside the bag body 21, and is roughly formed by a bonding means such as heat welding, ultrasonic welding, or bonding, and the bag body is disposed along a portion corresponding to the spacer. The inner wall surface is thermally welded to serve as a partition wall. In this manner, a plurality of spacers (the first spacer P1, the second spacer P2, and the third spacer P3) are formed, whereby the blood storage unit S1 that stores blood is stored and stored by the blood collection The air storage portion S2 of the air is excluded. That is, the partition walls of the spacers are divided into a blood reservoir S1 and an air reservoir S2.

<1st to 3rd spacers (P1 to P3)>

The following describes the specific arrangement of P1 to P3.

The first partition portion P1 forms a partition wall in a substantially lateral direction from a substantially oblique direction inside the bag body 21.

The second spacer P2 forms a partition wall in a substantially longitudinal direction inside the bag body 21.

The third partition portion P3 forms a partition wall in a substantially oblique direction or a substantially lateral direction inside the bag body 21.

In this regard, as described in more detail, the first spacer P1 and the third spacer P3 are formed in the "substantially oblique direction (or substantially the lateral direction)", and the reference may be along only the "oblique direction" and only along the " The horizontal direction is formed, or a straight line (curve) of the "oblique direction" and the "lateral direction" may be combined.

The second spacer P2 is formed in the "substantially longitudinal direction", and may be formed only in the "longitudinal direction" (vertical direction), or may be included in the (right or left) side wall surface SD direction of the bag body 21. It is formed in the "longitudinal direction" with a slight inclination.

<Positional relationship of the first to third spacers (P1 to P3)>

The first partition portion P1 is formed continuously from the lower portion of the second partition portion P2 to the (right) side wall surface SD (SDR) of the bag body 21 on the side opposite to the second partition portion P2. In other words, the partition portion is extended to the side portion SD (SDR), and the front end thereof is in contact with the wall surface SD and integrated to close, thereby defining the air storage portion S2.

The second partition portion P2 is formed on the side opposite to the side wall surface SD of the bag body 21 of the first partition portion P1, and is formed to be continuous in the upward direction. P2 and P1 together define the air storage portion S2, and form a space S between the opposing wall surface S for forming a comprehensive path or conduit.

In this regard, if it is described in more detail, the phrase "continuously formed in the upward direction" means that it may be formed to be vertically erected as shown in FIG. 1, or may be directed to the bag body 21. Side wall (right or left) The surface SD direction is formed by being slightly inclined and standing up. In short, it suffices that the air storage portion S2 and the space S can be formed.

The third partition portion P3 is formed between the air inducing portion R2 and the upper portion (left) wall surface UD of the bag body 21. The P3 system delimits the blood passage W1 and the rising air flow path W2.

<Additional Configuration of First to Third Spacer Parts (P1 to P3)>

An air introducing portion R2 introduced into the air storage portion S2 is formed in an upper portion of the second partition portion P2.

In this regard, as will be described in more detail, the air inducing portion R2 is inclined in the upper direction from the upper portion (end portion) of the second partition portion P2 to guide the blood inlet 23 or the upper (right) wall toward the bag body 21. The air rising in the direction of WD.

An inducer R1 for introducing blood into the blood reservoir S1 is formed below the third spacer P3.

In this regard, as will be described in more detail, the blood inducing portion R1 is formed to hang down in a substantially vertical direction from the lower portion (end portion) of the third partition portion P3. The term "following in a substantially vertical direction" means that it may be formed only in the "longitudinal direction", or may be slightly inclined in the "vertical direction" in the SD direction of the side wall surface of the bag body 21 (right or left). form.

The blood inducing portion R1 is formed in a short period in the blood collecting primary flow removing bag B of Fig. 1, and is formed longer in the blood collecting primary flow removing bag BB of Fig. 4, and can be optimally adapted according to the purpose. length.

Referring to Fig. 1, in the bag B, the blood inducing portion R1 is extended so as to protrude slightly in the downward direction from a position where the upper end portion of the second partition portion P2 intersects with the lower end portion of the air inducing portion R2.

In other words, the blood inducing portion R1 extends toward the lower portion of the bag body 21, and extends from the upper end portion of the second partition portion P2 to a position approximately 1/4 to 1/3 of the entire length of the second spacer portion P2. It depends on the requirement to define the space S for forming the overall flow path.

Further, referring to Fig. 4, in the case of the bag BB, the blood inducing portion R1 is substantially extended until the left end portion of the first spacer portion P1 and the lower end portion of the second spacer portion P2 intersect each other.

In other words, the blood inducing portion R1 extends toward the lower portion of the bag body 21, and is extended to a position substantially the same as the lower end portion of the second spacer portion P2 (allowing more or less the upper and lower offset).

<Formation position of the passage and the opening section> (in the case of bag B)

An air passage W2 that introduces air into the air storage portion S2 is formed between the air inducing portion R2 and the third partition portion P3. (Further, strictly speaking, the air passage W2 is a flow path mainly for circulating air, but it may also pass through one part of the blood that has been collected by blood sampling as will be described later.)

A third opening portion O3 that functions as an inlet for introducing air into the air storage portion S2 is formed between the front end portion of the air inducing portion R2 and the upper portion (right) wall surface WD of the bag body 21. (In addition, strictly speaking, regarding the third open part O3, as described later, it also passes through one part of the blood that has been collected by blood collection)

A blood passage W1 for blood to be collected is formed between the third partition portion P3 and the upper portion (left) wall surface UD of the bag body 21.

A first opening portion O1 (blood opening portion) having a function as an inlet of blood to the blood storing portion S1 is formed between the blood inducing portion R1 and the (left) side wall surface SD (SDL) of the bag body 21.

A second opening portion O2 (air inflow portion) having a function as an inlet to the air to the air storage portion S2 is formed between the blood inducing portion R1 and the second spacer portion P2 of the third partition portion P3. (Strictly speaking, regarding the second open part O2, as will be described later, one part of the blood that has passed through the collected blood)

(in the case of bag BB)

In the blood collection primary flow removing bag BB of Fig. 4, the blood inducing portion R1 is formed relatively long as described above, so that the defined air flow path W2 is further composed of two flow paths, and the air inducing portion R2 A second air passage W2.2 is formed between the third partition portion P3, and a first air passage W2.1 is formed between the second partition portion P3 and the blood inducing portion R1.

(Further, in the following, the first air passage W2.1 and the second air passage W2.2 are combined and referred to as the air passage W2.)

A blood passage W1.1 of the first blood is formed between the third partition portion P3 and the upper portion (left) wall surface UD of the bag body 21, and the blood inducing portion R1 and the (left) side wall surface SD of the bag body 21 ( A blood passage W1.2 of the second blood is formed between SDL). (The following is a case where the blood passage W1.1 of the first blood and the blood passage W1.2 of the second blood are combined only as the blood passage W1)

A first opening portion O1 (blood opening portion) having a function as an inlet of blood to the blood storing portion S1 is formed between the blood inducing portion R1 and the (left) side wall surface SD (SDL) of the bag body 21.

A second opening portion O2 (air inflow portion) having a function of opening the air to the air storage portion S2 is formed between the blood inducing portion R1 and the second spacer portion P2.

Further, the following contents are collectively recorded. The blood collection primary flow removing bags B and BB of the present invention are viewed from the left upper wall surface UD of the bag body 21 to the left side wall surface SD (SDL) direction with reference to Figs. 1 and 4, and to the upper left portion of the bag body 21. The blood passage W1 is formed in such a manner that the wall surface UD is in contact with the left side wall surface SD (SDL), and is formed in the bag body 21 along the blood passage W1 formed to be in contact with the left upper wall surface UD to the left side wall surface SD (SDL). The air passage W2 is formed near the substantially central direction.

In the blood collection primary flow removing bag B of Fig. 1, the term "close to the substantially central direction" means that the third spacer portion P3 is formed between the third spacer portion P3 and the air inducing portion R2 (not in contact with the left upper wall surface UD). Air passage W2.

In the blood collection primary flow removal bag BB of FIG. 4, the "close to the substantially central direction" is (not in contact with the left upper wall surface UD to the left side wall surface SD (SDL)) along the third partition portion P3 and the air. The air passage W2 is formed between the inducing portion R2 and between the second partition portion P2 and the blood inducing portion R1.

<Connectivity between the passage and the open part and the storage part>

The blood passage W1 communicates with the blood storage portion S1 via the inlet 23 of the primary blood and the first opening portion O1 (blood opening portion).

The air passage W2 communicates with the blood storage portion S1 via the second opening portion O2 (air inflow portion), and communicates with the air storage portion S2 via the third opening portion O3 (air opening portion).

<Location relationship of the open department>

The first opening portion O1 (blood opening portion) having a function as an inlet port for blood to the blood storing portion S1 and a second opening portion O2 (air inflow portion) having a function as an inlet to the air to the air storing portion S2 The blood inducing portion R1 is placed adjacent to each other via the third spacer P3.

The first opening portion O1 is formed in contact with the left side wall surface SD (SDL), and the second opening portion O2 (not in contact with the left side wall surface SD and the upper wall surface UD) is in the blood inducing portion R1 and the first spacer portion. The left end portion of P1 (the lower end portion of the second partition portion P2) is formed between the right upper wall surface WD and the right end portion of the air induction portion R2 so as to be in contact with the right upper wall surface WD. .

<Integration of blood and air flow paths (formation of the overall flow path)>

In the blood collection primary flow removing bag B of Fig. 1, the space S between the second partition portion P2 formed in the bag body 21 and the side wall surface SD (SDL) of the bag body 21 is also introduced as a blood storage portion. The function of both the blood inflow path of the blood of S1 and the exhaust gas flow path of the air introduced into the air storage unit S2 is a so-called overall flow path.

On the other hand, in the blood collection primary flow removing bag BB of FIG. 4, the first air passage W2.1 and the second air passage W2.2 have a function as an exhaust flow path of the air introduced into the air storage portion S2.

<(The first to third spacers (P1 to P3), the specific components such as the induction portions R1 and R2)>

The first partition portion P1 and the second partition portion P2 are formed in the direction from the (right) side portion of the bag body 21 in the direction of the upper portion and further in the direction of the inlet 23 of the primary blood flow through the substantially central direction. Word shape Font).

The inlet 23 of the primary blood is substantially at the center, and the inlet 23 of the primary blood is inclined upward (in a rising manner) to form an upper (left) wall surface UD of the bag body 21 (as shown in FIG. The side closer to the partition P3).

The upper (right) wall surface WD of the other bag body 21 is also inclined toward the inlet 23 of the primary blood (in a rising manner) (the side farther from the third spacer P3 as shown in FIG. 1). It is preferable that the inclination of the upper (right) wall surface WD is gentler than that of the upper (left) wall surface UD. The reason why the inclination of the left upper wall surface UD is larger is that the inner wall surface of the UD needs to form a part of the flow path that smoothly receives the blood and flows it down.

Similarly to the upper (left) wall surface UD of the bag body 21, the air inducing portion R2 at the upper portion of the second partition portion P2 is inclined toward the inlet 23 of the primary blood (in a rising manner). It all depends on the requirement to ensure a smooth flow of blood or air.

Further, the upper (left) wall surface UD of the bag body 21 and the air inducing portion R2 at the upper portion of the second partition portion P2 are inclined substantially parallel to the inlet 23 of the primary blood (in a rising manner).

The third spacer P3 is inclined toward the inlet 23 of the primary blood (in a rising manner).

The upper (left) wall surface UD, the third partition portion P3, and the air inducing portion R2 of the bag body 21 are preferably inclined so as to be substantially parallel to each other, toward the inlet 23 of the primary blood (in a rising manner). .

When the initial blood is introduced from the inlet 23 of the primary blood in the upper portion of the bag body 21 and stored in the empty blood storage portion S1 of the bag body 21, the air in the blood storage portion S1 is removed by the blood taken. The air is stored in the air storage unit S2 via the second opening portion O2 (air inflow portion), the air passage W2, and the third opening portion O3 (air opening portion).

(the size of the air passage, etc.)

It is preferable that the width of the air passage W2 is set to about 2 to 5 mm. When the width of the air passage W2 is narrower than this, when the blood is taken, there is a possibility that the air cannot smoothly move to the air storage portion S2. On the contrary, if the width of the air passage W2 is too wide, the air cannot be surely It is not preferable to move to the air storage portion S2, or the air that has moved to the air storage portion S2 once is reversed from the vacuum blood collection tube holder 22 to the vacuum blood collection tube.

Further, it is preferable that a narrow portion (not shown) is formed in a portion of the middle of the air passage W2, and the flow path is narrowed locally, and the difference in fluid resistance between the air and the blood is used to make it easy for air to pass through the blood. Construction. In the narrowed portion of the narrowed portion, the diameter of the passage is suitably about 0.5 to 2 mm. Further, it is preferable that the stenosis portion is formed at a position where the blood follows the air and blood when the blood is collected by a predetermined amount. Further, instead of narrowing a part of the passage of the air passage W2, a backflow prevention valve or the like (for example, a one-way valve such as a duckbill valve) may be provided.

The above-described structure regarding the air passage is used in the blood collection operation, in order to prevent the blood from being excessively taken when the blood reaches a predetermined amount, and to prevent the excessive use of the blood, and to take the air to the air storage portion S2 once from the vacuum blood collection tube holder 22 When the blood is taken from a blood collection tube, it is prevented from flowing back.

Further, as described above, in the air passage W2, the portion corresponding to the second partition portion P2 and the third partition portion P3 is substantially parallel to the upper (left) wall surface UD in the inner wall surface of the bag body 21 The spacers P2 and P3 are formed by heat welding or the like, and are formed as an air passage W2 between the upper (left) wall surface UD, but the first opening portion O1 located at the lower portion of the spacers P2 and P3. The open portion O2 is formed as a portion where the heat fusion or the like is not welded. The third opening portion O3 located above the air inducing portion R2 is formed by not performing the heat welding or the like.

Further, the reason why the second opening portion O2 (non-welding portion) is the same as the width of the air passage W2 is preferably set to about 2 to 5 mm.

Further, when the primary blood flows into the blood reservoir S1, the first open portion O1 (non-welded portion) and the excluded air (the initial air) originally present in the bag body 21 are retained (air storage portion S2). It is connected so that it is preferably formed wider (larger) than the second opening portion O2 (non-welded portion) to store air.

Further, when the air storage portion S2 is formed sufficiently wide, the air that has been removed and accommodated in the air storage portion S2 during the blood collection is compressed in the bag, and the inside of the bag is not excessively pressurized. Therefore, the force exerted by the elastic force of the bag or the air at the time of blood collection does not substantially exert its effect on the pressure of the inflowing blood, and the blood can be smoothly collected in a desired amount, so that the amount of blood collection is insufficient, so that good.

Further, when the volume of the blood storing portion S1 is formed substantially in the same manner as the predetermined amount of blood to be taken, when the blood is completely filled in the blood storing portion S1, the blood starts to overflow into the air storing portion S2. Therefore, in such a configuration, the moment when the blood starts to overflow, the blood can be easily confirmed to reach a predetermined amount, and the application of the end operation or the like can be quickly taken.

In the present invention, when the blood is retained from the blood storage portion S1 to the third open portion O3, it can be considered that the predetermined amount of blood to be taken can be taken.

(size of blood pathway)

It is preferable that the width of the blood passage W1 is set to 3 to 7 mm, preferably 6 to 10 mm, more preferably 7 to 8 mm. If the width is too narrow (especially if it is less than 3 mm), when the blood is taken, there is a possibility that the blood of the first blood collection will not flow down to the blood storage portion S1 rapidly. If it is wide (especially if it exceeds 10 mm), the first air in the blood storage portion is caught in the blood flowing down, and it is not preferable to remove only the air to the air storage portion S2.

(The relationship between the size of the blood passage and the air passage, etc.)

In the present invention, the width of the blood passage W1 is formed larger than the width of the air passage W2, and as a result, the width of the blood passage of the blood collection primary flow removing bag (BD) described in Fig. 8 of Patent Document 7 is wider. The "width of the blood passage W1" is formed more.

Further, the width of the blood passage W1 is set to be equal to or greater than 120 and less than 300, preferably equal to or greater than 120 and less than 200, and more preferably greater than the width of the air passage W2. Equal to 120 and less than 150.

(take measures to the blood of the outer container)

The means for taking the blood taken into the blood collection bag B or the bag BB to the external container for inspection or the like is not particularly limited as long as blood can be taken to the external container. For example, as shown in FIG. The outlet 24 of 21 is used by mounting the vacuum blood collection tube holder 22. Alternatively, a connector tube (connecting the connector at the front end of the tube) may be used.

As a specific means for taking blood to the external container, when the vacuum blood collection tube holder 22 shown in Fig. 1 is used, as shown in Fig. 1, the needle 25 for the initial blood is attached to the outlet 24, and the needle is taken. A vacuum blood collection tube holder 22 is attached to the periphery of 25. The needle 25 is taken up by the sheath 26.

After the blood is taken in the blood storage portion S1 of the bag body 21, a vacuum blood collection tube (not shown) is inserted into the vacuum blood collection tube holder 22, and the blood in the bag body 21 is collected in the vacuum blood collection tube.

(blood bag 2)

In the present invention, the blood bag 2 is, for example, as shown in FIG. 2 (or FIG. 5), in a narrow sense, the mother bag 4, the blood filter 3, the first sub-bag 5, the second sub-bag 6, and the bag 7 containing the red blood cell preservation liquid ( And a blood bank including the blood circuit, which is a unified name of a plurality of bags for storing blood collected from a blood donor (donor) as a blood transfusion circuit, and broadly includes a blood collection circuit It is used to construct a blood bag 2 in which the blood collection and storage system of the blood bag having the initial flow removing function is incorporated in a portion of the blood collection circuit.

A blood collection tube T1 is connected upstream of the mother bag 4 to form a blood collection circuit. In the blood collection tube T1, a blood collection needle 8, a branch tube 13a, and a flow path clogging means 12 are connected from the front end (upstream) to the middle thereof. In the branch pipe 13a, the blood collection primary flow removing group 1 is connected to the preliminary blood introducing pipe T2 (in the intermediate mounting jig 11a) as a portion forming an initial flow removing circuit which is an additional feature of the present invention.

In this regard, in more detail, as illustrated in FIG. 1, the flow path clogging means 12 may be a communication piece disposed inside the blood collection tube T1 (in the initial preset setting, the piece closes the fluid flow path, The primary flow is forcibly introduced into the tube T2. By breaking the closure, the self-collecting blood vessel T1 is opened to the liquid flow path of the mother bag 4. Further, as exemplified in Fig. 2, the jigs 11a and 11c which are attached to the outer sides of the respective tubes T1, T2, and T3 and which are closed by the switch, can open and close the liquid flow path.

The blood filter 3 and the first sub-bag 5 are connected to the downstream of the mother bag 4 via a connecting tube T3. The blood filter 3 is a white blood cell that captures and removes a cause of side effects such as fever in the blood, and is filled with a porous fiber material such as a nonwoven fabric having a fine fiber diameter in a substantially disk-shaped resin case (housing). In Fig. 2, a plan view of the outer casing is described, and the blood inlets on the back side of the paper surface and the blood outlets on the surface (front surface) of the paper surface are respectively connected to the tube T.

Further, the first sub-bag 5 is connected to the second sub-bag 6 and the bag 7 containing the red blood cell preservation liquid via the connection tube T4, the branch tube 13b, and the connection tubes T5 and T6.

In order to prevent or preserve the coagulation of blood during blood collection or blood transfusion, the mother bag 4 and the bag 7 containing the red blood cell preservation solution contain, for example, ACD (Acid Citrate Dextrose) liquid, CPD (Citrate Phosphate). Dextrose, dextran citrate phosphate, CPDA (Citrate Phosphate Dextrose Adenine), anticoagulant or MAP (Mannitol Adenine Phosphate) Red blood cell preservation solution.

(material, etc.)

As a material constituting the pouch of the blood collection first stream removing bag B (or BB) and the blood bag 2, for example, it is possible to use, without limitation, a resin which is generally used such as polyvinyl chloride or polyethylene or polypropylene. Synthetic resin.

(Example of use of blood collection first stream removal group 1 or blood collection primary flow removal bag B, BB)

An example of a method of using the blood collection primary flow removing group 1 or the blood sampling primary flow removing bag B of the present invention as shown in Fig. 1 or Fig. 2 described in detail above will be described with reference to Fig. 3 (or Fig. 6).

(i) Steps from (A) to (B) of Figure 3 and Figure 6:

Fig. 3 and Fig. 6(A) show the blood primary flow removal group 1 before blood collection is started, and the blood is not introduced into the blood collection primary flow bag B, and only the first air exists in both S1 and S2.

3 and 6(B) show a state in which blood collection is performed, and the primary blood BL is introduced into the blood storage unit S1 from the inlet 23 through the blood passages W1 (W1.1, W1.2) and the first opening portion O1. On the other hand, the first air of the blood reservoir S1 is extruded by the introduction of the primary blood, and is introduced to the second opening O2, the air passage W2 (W2.1, W2.2), and the third opening O3. In the air storage unit S2.

(ii) Steps in Figure 3 and Figure 6(C):

When the introduction of the primary blood is continued, as shown in FIG. 3(C), the primary blood BL overflows from the blood storage unit S1, and the blood level is filled with the air passage W2 from the second opening O2 (W2.1, W2). .2) While rising, through the air passages W2 (W2.1, W2.2) and the third opening portion O3, a part of the blood BL' is introduced into the air storage portion S2.

(iii) Steps from (D) to (E) of Figures 3 and 6:

The step of changing the initial blood collection bag B (inverted) and taking the stored initial blood at the time point of changing to FIG. 3 and FIG. 6(C) is performed on the upwardly facing vacuum blood collection tube holder 22 The needle 25 is equipped with a vacuum blood collection tube (not shown) to take primary blood.

When the bag is reversed, as shown in Figs. 3 and 6(D), the primary blood is moved from the blood storage unit S1 to the air storage unit S2 by its own weight, and is introduced into the air storage unit at one time. Then, in the step of taking blood by taking the needle 25 and taking a blood collection tube (not shown), the blood BL in the air storage portion S2 gradually passes through the third opening portion O3 as shown in FIGS. 3 and 6(E). The air passages W2 (W2.1, W2.2) and the second opening portion O2 are again moved to the blood storage portion S1, and are taken to a vacuum blood collection tube (not shown) via the take-up needle 25. Then, the air in the air storage portion S2 is completely sealed in the air storage portion S2, and is not moved to the blood storage portion S1 via the third opening portion O3, the air passages W2 (W2.1, W2.2), and the second opening portion O2. .

In the blood collection primary flow removing bag B of Fig. 1 of the present invention, the space S formed between the second partition portion P2 formed in the bag body 21 and the side wall surface SD of the bag body 21 serves as the introduction into the blood storing portion S1. Since the blood inflow path of the blood and the function of the air flow path of the air introduced into the air storage unit S2 form an entire flow path, it is described in Patent Document 7 [by a plurality of spacers (P1). The P2 and P3) are formed by the blood collection unit S2, and the blood collection time removal bag (BA', BD) formed by separating the blood passage W1 and the air passage W2 on both sides can shorten the "blood collection time".

In the blood collection primary flow removing bag BB of FIG. 4 according to another embodiment of the present invention, the air passage W2 (including the first air passage W2.1 and the second air passage W2.2) is provided as an air introduction portion S2. The function of the exhaust flow path of the air (the air extruded through the first blood passage W1.1 and the second blood passage W1.2 along the air passage).

It is considered that the blood collection preliminary flow removing bag BB of the present invention is viewed from the left upper wall surface UD of the bag body 21 to the left side wall surface SD (SDL) direction, and to the left upper wall surface UD of the bag body 21 to the left side wall surface SD. The blood passage W1 is formed by contact, and the air passage W2 is formed in the substantially central direction of the bag body 21 (in the manner of forming the blood passage W1 that is in contact with the left upper wall surface UD to the left side wall surface SD). Therefore, the present invention In the blood collection primary flow removing bag BB of FIG. 4, the blood storage portion S1 expands due to the inflow of blood, and the air passage W2 is easily expanded to allow the air to smoothly flow, and the air is likely to remain in the air storage portion S2. Along with this, it can be considered that the blood collection time can be shortened because it is difficult to apply the resistance when the blood flows in.

On the other hand, in the blood collection primary flow removing bag (BA', BD) described in FIGS. 6 and 8 of Patent Document 7, the blood passage W1 is separated from the air passage W2 so as to be in contact with the side wall surface of the bag body. Formed, so it is obvious that this effect is not exerted.

In the blood collection primary flow removing bags B and BB of the present invention, as described above, the width of the blood passage W1 is formed to be wide, thereby contributing to shortening of the blood collection time of the primary blood.

In the blood collection primary flow removing bags B and BB of the present invention, as described above, the width of the blood passage W1 is larger than the width of the air passage W2, and the width (area) of the blood passage W1 occupied in the bag body is large.

In other words, with respect to the width 100 of the blood passage W1 of the blood collection primary flow removing bag (BD) described in Fig. 8 of Patent Document 7, in the present invention, the width of the blood passage W1 of the blood collection primary flow removing bag (B, BB) is removed. It is preferably formed to be, for example, 100 to 200, more preferably 140 to 180. It was confirmed that the blood collection time can be shortened, for example, by forming the width of W1 to 175 (1.75 times).

In the first embodiment (the blood collection preliminary flow removing bag B of Fig. 1) and the second embodiment (the blood collecting primary flow removing bag BB of Fig. 4), the width of the blood passage W1 was "7 mm", and Comparative Example 1 [ In the blood collection primary flow removal bag (BD) described in FIG. 8 of Patent Document 7, the width of the blood passage W1 is set to "4 mm", and the blood collection time is compared, and it can be confirmed that the blood collection time is greatly shortened in comparison with the comparative example. .

[Examples]

An example in which a blood collection bag using the blood collection preliminary flow removing bags B and BB of the present invention is actually subjected to a simulated blood sampling test to measure the blood collection time will be described.

(1) As the first embodiment and the second embodiment, the blood bag 2 (the blood collection primary flow removing bag B, BB) having the configuration shown in Fig. 2 was used. That is, as the first embodiment, the blood bag 2 (B) having the configuration of Fig. 2 was used, and as the second embodiment, the bag (BB) of Fig. 4 was used instead of the bag 2 (B) of Fig. 2 .

(2) As the comparative example 1, in the blood bag 2 of Fig. 2, the blood collection primary flow removing bag BD shown in Fig. 8 of Patent Document 7 is used instead of the blood collection primary flow removing bags B and BB.

(3) Measurement conditions, etc.

(i) Regarding the "blood collection time θ", in the blood collection first flow removal bags B and BB of the first embodiment and the second embodiment, the blood flow from the blood donor is puncture, and the first blood is retained in the blood storage unit S1. 3 The air opening portion O3 until the time when one drop falls into the air storage portion S2 (the time until the end of the initial blood flow is completed).

Further, in the blood collection preliminary flow removing bag BD of Comparative Example 1 (described in FIG. 8 of Patent Document 7), the blood collection time θ is that the first blood stagnates in the blood storage portion S1 and reaches the upper opening portion O1 until one drop falls into the air. The time until the storage unit S2 (the time until the end of the initial blood flow is completed).

(ii) As test blood, use (A) "human blood", (B) "artificial blood" (PVP (polyvinyl pyrrolidone) and sorbitol mixture, PVP: 3 wt%, sorbitol : 5 wt%) The measurement was performed separately.

(4) Experimental content and test results

In the test using (A) "human blood", 6 tests were carried out in Example 1, and 20 tests were carried out in Example 2. In the test of "artificial blood" in (B), the first blood-removing bag of the present invention (Example 1, Example 2) was subjected to 20 tests, and the first blood-removing bag of Comparative Example 1 was subjected to 10 tests.

The results are shown in Table 1.

(Exploration of results)

As can be seen from Table 1, it can be confirmed that in Example 1 in which the blood bag B was used, the average value of the fastest value and the slowest value of the blood collection time θ was compared with that of Comparative Example 1, and the average of (A) "human blood" was shortened. 15 seconds (about 30%) of blood collection time, (B) "artificial blood" reduced by an average of 14 seconds (about 36%) blood collection time.

Further, in Example 2 in which the blood bag BB was used, the average value of the blood collection time θ was similar to that of the comparative example 1 in that (A) "human blood" was shortened by an average of 15 seconds (about 30%). In (B) "artificial blood" was shortened by an average of 14 seconds (about 36%).

As a result, the blood collection preliminary flow removing bags B and BB of the present invention have a significant reduction in the blood sampling time compared with the blood collection primary flow removing bag BD of Comparative Example 1 using a conventional blood bag, and the medical treatment thereof is exhibited. The significance of the scene is great.

1‧‧‧ Blood collection first stream removal group

2‧‧‧blood bag

3‧‧‧Blood filter

4‧‧‧ mother bag

5‧‧‧1st sub-bag

6‧‧‧2nd sub-bag

7‧‧‧Bag with red blood cell preservation solution

8‧‧ ‧ blood collection needle

10‧‧‧ needle cover

11a, 11c‧‧‧ fixture

12‧‧‧Flow path blocking means (connecting piece)

13a, 13b‧‧‧ branch pipe

21‧‧‧ bag body

22‧‧‧Vacuum blood collection stent

23‧‧‧ (primary blood) entrance

24‧‧‧ (primary blood) exports

25‧‧‧ (primary blood) needle

26‧‧‧ sheath

B, BB‧‧ ‧ blood collection first stream removal bag

O1‧‧1 first open department (inlet of blood, open part of blood)

O2‧‧‧2nd opening (air inlet, air inflow)

O3‧‧‧3rd Open Department (air entrance, air opening department)

P1‧‧‧1st compartment

P2‧‧‧2nd spacer

P3‧‧‧3rd spacer

R1‧‧‧ Blood Induction Department

R2‧‧‧Air Induction Department

S‧‧‧ used to form the space of the overall flow path

S1‧‧‧ Blood Storage Department

S2‧‧‧Air Storage Department

SD‧‧‧ side wall

SDL‧‧‧ left side wall

SDR‧‧‧ right side wall

T1. . . Blood collection tube

T2. . . Primary blood introduction tube

T3, T4, T5, T6. . . Connecting tube

UD. . . Upper left wall

WD. . . Right upper wall

W1. . . Blood pathway

W1.1. . . First blood passage

W1.2. . . Second blood passage

W2. . . Air passage

W2.1. . . First air passage

W2.2. . . Second air passage

Fig. 1 is a schematic view of the blood collection primary flow removing group 1 of the present invention including the blood sampling primary flow removing bag B.

Fig. 2 is a schematic view showing a blood collection and storage system for the blood bag 2 to which the blood collection primary flow removing group 1 of the present invention (including the blood collection primary flow removing bag B) is applied.

3(A) to 3(E) are schematic diagrams showing an example of a method of using the blood collection primary flow removing bag B in Fig. 1.

Fig. 4 is a schematic view showing a blood collection primary flow removing bag BB as another embodiment (Embodiment) of the present invention.

Fig. 5 is a schematic view showing a blood collection and storage system for the blood bag 2 to which the blood collection primary flow removing group 1 of the present invention (including the case of the blood sampling primary flow removing bag BB) is applied.

6(A) to 6(E) are schematic diagrams showing an example of a method of using the blood collection primary flow removing bag BB in Fig. 4.

1. . . Blood collection first stream removal group

8. . . Blood collection needle

10. . . Needle cover

11a. . . Fixture

12. . . Flow path blocking means (connecting piece)

13a. . . Branch tube

twenty one. . . Bag body

twenty two. . . Vacuum blood collection tube stent

twenty three. . . (primary blood) entrance

twenty four. . . (primary blood) export

25. . . Taking a needle (initial blood)

26. . . jacket

B. . . Blood collection first stream removal bag

O1. . . The first open part (the entrance of the blood, the open part of the blood)

O2. . . The second open part (air inlet, air inflow part)

O3. . . The third open part (air entrance, air open part)

P1. . . First spacer

P2. . . Second spacer

P3. . . Third spacer

R1. . . Blood induction department

R2. . . Air induction department

S. . . Space used to form the overall flow path

S1. . . Blood storage department

S2. . . Air storage department

SD. . . Side wall

SDL. . . Left side wall

SDR. . . Right side wall

T1. . . Blood collection tube

T2. . . Primary blood introduction tube

UD. . . Upper left wall

WD. . . Right upper wall

W1. . . Blood pathway

W2. . . Air passage

Claims (13)

A blood collection primary flow removing bag (B, BB), which is a person who stores blood from a blood donor and is used for blood for examination thereafter; and is characterized in that: a bag body (21) for storing initial blood is provided. Forming an inlet (23) for the primary blood on the upper portion of the bag body (21), forming an outlet (24) for the primary blood at a lower portion of the bag body (21); the bag body (21) having at least a zone The upper upper wall surface (UD, WD) and the side wall surface (SD) of the partition side; the inside of the bag body (21) is composed of a plurality of first partitions (P1), second spacers (P2), and third a partition (P3) partitioned into a blood storage unit (S1) for storing blood and an air storage unit (S2) for storing air removed by the blood; the first spacer (P1) is from the bag a partition wall is formed in a substantially oblique direction in a substantially oblique direction inside the main body (21), and the second partition portion (P2) forms a partition wall along a substantially longitudinal direction inside the bag body (21); the third partition portion ( P3) forming a partition wall in a substantially oblique direction or a substantially lateral direction inside the bag body (21); the first spacer (P1) is from the second Spacer portion (P2) portion from below, and across to the second spacer portion (P2) opposite to the bag body (21) of the side portion of the side wall (SD) are formed continuously; The second partition portion (P2) is formed on the side opposite to the side wall surface (SD) of the bag body (21) of the first partition portion (P1), and is continuously formed to stand in the upward direction. The third spacer (P3) is formed between the second spacer (P2) and the upper wall surface (UD) of the bag body (21), and is introduced at the upper portion of the second spacer (P2). An air inducing portion (R2) to the air storage portion (S2); an inducing portion (R1) for introducing blood into the blood storing portion (S1) at a lower portion of the third partition portion (P3); An air passage (W2) for introducing air to the air storage portion (S2) is formed between the air inducing portion (R2) and the third partition portion (P3); and at the front end portion of the air inducing portion (R2) A third opening portion (O3) that functions as an inlet for introducing air into the air storage portion (S2) is formed between the upper wall surfaces (WD) of the bag body (21); and the third spacer portion is formed in the third spacer portion. (P3) a blood passage (W1) for blood to be collected between the upper wall surface (UD) of the bag body (21); the blood inducing portion (R1) and the bag body (21) Between the side wall surfaces (SD), a first opening portion (O1) having a function as an inlet port for blood to the blood storing portion (S1), and a blood introducing portion at the third spacer portion (P3) are formed. Between (R1) and the second spacer (P2), a second opening (O2) having a function as an inlet to the air of the air storage unit (S2) is formed; The blood passage (W1) communicates with the blood storage unit (S1) via the inlet (23) of the primary blood and the first opening (O1), and the air passage (W2) is opened via the second opening The portion (O2) communicates with the blood storage portion (S1), communicates with the air storage portion (S2) via the third opening portion (O3), and has an inlet for blood to the blood storage portion (S1). The first open portion (O1) of the function and the second open portion (O2) having a function as an inlet for the air to the air storage portion (S2), the blood interposed between the third spacer (P3) The inducing portion (R1) is adjacent to each other; viewed from the left upper wall surface (UD) to the left side wall surface (SD) direction of the bag body (21), and to the left upper wall surface (UD) of the bag body (21) to The blood passage (W1) is formed so as to be in contact with the left side wall surface (SD), and the air passage (W2) is formed in the substantially central direction of the bag body (21) along the blood passage (W1). The blood collection primary flow removing bag (B, BB) according to the first aspect of the patent application, wherein the first spacer (P1) and the second spacer (P2) are from one side of the bag body (21) The direction is continuous in the direction of the upper direction and the inlet (23) of the primary blood through the substantially central direction. Word shape. The blood collection primary flow removing bag (BB) according to the second aspect of the invention, wherein the blood inducing portion (R1) extends from the third partition portion (P3) to the first partition portion (P1). The side end portion is adjacent to the intersection of the lower end portion of the second spacer portion (P2). The blood collection primary flow removing bag (BB) according to the third aspect of the patent application, wherein the first air passage (W2.1) is formed between the second partition portion (P3) and the blood inducing portion (R1). a second air passage (W2.2) is formed between the air inducing portion (R2) and the third partition portion (P3); the first air passage (W2.1) and the second air The passage (W2.2) has a function as an exhaust flow path of the air introduced into the air storage portion (S2). The blood collection primary flow removing bag (B) according to the second aspect of the invention, wherein the blood inducing portion (R1) faces the lower portion of the bag body (21), from the upper end portion of the second spacer portion (P2) The extension is set to a position of approximately 1/4 to 1/3 of the entire length of the second spacer (P2). The blood collection primary flow removing bag (B) according to the fifth aspect of the patent application, wherein the second partition portion (P2) formed in the bag body (21) and the side wall surface of the bag body (21) (SD) The space (S) between the two is a function of both the blood inflow path as the blood introduced into the blood storage unit (S1) and the exhaust flow path of the air introduced into the air storage unit (S2). . The blood priming bag (B, BB) of claim 2, wherein a width of the blood passage (W1) is formed larger than a width of the air passage (W2); and the air passage (W2) is opposite to the air passage (W2) The width is 100, and the width of the blood passage (W1) is 120 to 300. For example, the blood initial flow removal bag (B, BB) of the second application patent scope, wherein The upper wall surface (UD) of the bag body (21) is formed so as to be inclined toward the inlet (23) of the primary blood, and the second spacer (P2) is formed so as to be substantially at the entrance (23) of the primary blood. The upper air inducing portion (R2) is formed to be inclined toward the inlet (23) of the primary blood, similarly to the upper wall surface (UD) of the bag body (21). The blood collection primary flow removing bag (B, BB) according to the second aspect of the patent application, wherein the upper wall surface (UD) of the bag body (21) and the air inducing portion of the upper portion of the second spacer portion (P2) (R2) ) are formed so as to be inclined substantially parallel to the inlet (23) of the primary blood. For example, the blood collection primary flow removing bag (B, BB) of the second application of the patent scope, wherein the initial blood is initially introduced from the inlet (23) of the primary blood in the upper part of the bag body (21) and stored in the empty one. In the blood storage unit (S1) of the bag body (21), the air in the blood storage unit (S1) is removed by the blood taken, and passes through the second opening portion (O2) and the air passage (W2). The third open portion (O3) is housed in the air storage portion (S2). For example, in the first blood collection bag (B, BB) of the second application of the patent scope, when blood is accumulated from the blood storage unit (S1) to the third opening (O3), it can be regarded as The prescribed amount of blood taken. A blood collection primary flow removal group (1), characterized in that: the first blood collection outlet (24) of the blood collection primary flow removal bag (B, BB) in any one of claims 1 to 11 of the patent application form, thereby forming Take the means to the blood of the outer container. A blood bag (2) having an initial flow removing function, which is composed of a blood mother bag (4) and a plurality of sub-bags (5, 6); characterized in that: an initial blood introduction tube (T2) is connected to a branch pipe (13a) disposed in the middle of the blood collection tube (T1) to which the blood collection needle (8) is connected upstream, and the blood collection initial flow removal group (1) of the patent application scope 12 is connected to the preliminary blood introduction tube Downstream of (T2).