JP4879704B2 - Blood collection initial flow removal bag, blood collection initial flow removal set and blood bag - Google Patents

Blood collection initial flow removal bag, blood collection initial flow removal set and blood bag Download PDF

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JP4879704B2
JP4879704B2 JP2006294611A JP2006294611A JP4879704B2 JP 4879704 B2 JP4879704 B2 JP 4879704B2 JP 2006294611 A JP2006294611 A JP 2006294611A JP 2006294611 A JP2006294611 A JP 2006294611A JP 4879704 B2 JP4879704 B2 JP 4879704B2
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blood
bag
partition
bag body
blood collection
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JP2008110043A (en
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聡 徳光
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川澄化学工業株式会社
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Description

  The present invention relates to a blood collection initial flow removal bag and a blood collection initial flow removal set capable of collecting initial flow blood and easily collecting test blood.

When blood collected from a blood collection needle is introduced into a blood bag, the donor's puncture position is sterilized with alcohol, etc., but even if the sterilization is performed, bacteria existing in the skin and subcutaneous will be mixed into the collected blood. Sometimes.
Depending on the type of bacteria, the contaminated bacteria can grow even while the blood bag is stored, and if used for blood transfusion without noticing the growth of the bacteria, it can cause infections in the transfused patient and cause serious infections. There is also a risk that this will happen.
Therefore, a system for removing the initial blood at the time of blood collection has been invented so that the collected blood can be prevented from being contaminated with bacteria.

Patent Document 1 describes a sampling system that can collect test blood while maintaining sterility between a blood donor and a collection container at the beginning of a blood donation procedure.
A discharge tube 43 extends into a substantially circular inner chamber 54, and a holder 60 that holds a liquid sample vial 70 is formed so as to be connected to an outlet port 50 that communicates with the discharge tube 43. Further, when blood or the like in the internal chamber 54 is drawn from the container 42 to the sampling vial by the discharge tube 43 extending to the vicinity of the inlet port 46 in the internal chamber 54, air is not allowed to enter the sampling vial. ing.

Patent Document 2 to Patent Document 5 describe a container assembly that can collect a collected blood initial flow, and can improve the accuracy of a bacterial test of the collected blood and the workability in the bacterial test, It is described that the safety when using the collected blood can be improved.
Specifically, for example, in Patent Document 4, a tube 91 is connected to a branch connector 92 formed in the middle of the tube 15 of the blood collection device 1 having the blood collection bag 10 and the blood collection needle 152 connected by the tube 15, A blood bag 20 for temporarily storing blood is connected to the end. A tube 96 having a sampling port 71 formed at the tip is connected to the bag 20. Since the blood collection device 1 can easily and safely introduce the collected initial blood into a blood collection tube connected to the sampling port 71 and perform a bacterial test, the reliability of the bacterial test is increased.

Patent Document 6 describes a blood bag that is divided into a blood component storage chamber 42 and a blood component lower outlet channel 41 by forming a partition 40 in the blood collection bag 32. In the vicinity of the upstream side of the passage 39 formed by the partition portion 40, the closing members 10, 20, and 43 are mounted.
By partitioning the blood bag with the partition 40, the intermediate layer remains in the blood bag 32 while maintaining the state in which the blood components are not mixed with each other after separation into an upper layer, an intermediate layer, and a lower layer by centrifugation. In addition, the upper layer breaks down the blocking members 10, 20, 43 from the upper outlet 39 a to the separation bag 33, and separates and discharges to the outlet 39 b and the separation bag 34 through the outflow passage 41 formed by the partition 40. Can be made.

In the invention of Patent Document 1, when collecting blood in the container 42, it is difficult to take in air even if the sampling system is inverted by the discharge tube 43, but it is not possible to prevent the air inside the discharge tube 43 from being taken into the sampling vial. . Further, since blood is taken in through the discharge tube 43, blood can be taken into the sampling vial little by little, and blood collection work from the container 42 to the sampling vial cannot be performed quickly. Further, there is a restriction that the sampling system must be inverted when collecting blood in the container 42.
In the inventions of Patent Document 2 to Patent Document 5, although the removal of initial blood and blood sampling can be performed, the blood collection device is in a low position when collecting blood from a blood donor due to the structure of the bag. Blood must be sampled from an unreasonable posture such as crouching or crouching, and it is very painful to perform the same work many times in a narrow place such as a blood donation car.
In addition, it is necessary to keep an eye on the mark attached to the bag when collecting a prescribed amount of blood in the bag, and further, the patient will bend in the sampling, so the donor's observation will be neglected and the donor's condition will change May not be able to respond immediately.
Moreover, the partition part 40 currently formed in the bag 31 of patent document 6 is an outflow port of the isolate | separated blood, and mounting | wearing of the obstruction | occlusion members 10, 20, and 43 is required.

JP-T-2003-505185 ([Claims], [0026], [0034]) Japanese Patent Laid-Open No. 10-84942 ([Claims], FIG. 1) JP 11-197236 A ([Claims], FIG. 1) JP 2001-17539 A ([0085] to [0093], FIG. 1) Japanese Patent Laying-Open No. 2005-279289 ([0037], FIG. 1) Japanese Patent No. 3179208 ([Claim 3], [0015], [0016], FIG. 5)

  The problem to be solved by the present invention is that when blood collected in the blood collection initial flow removal bag is collected into a vacuum blood collection tube from an external blood collection means such as a vacuum blood collection tube holder, air must be taken into the vacuum blood collection tube. In order to prevent air from being taken in, the structure of the blood bag makes the blood from the unreasonable posture that the operator bends or crouches because the blood collection system is in the low position during blood collection. In the past, it was confirmed that the specified blood volume was collected in the initial blood removal bag by matching the mark on the bag with the blood level. In other words, excessive or insufficient blood collection may occur.

[1] The present invention is a blood collection initial flow removal bag for storing initial flow blood collected from a blood donor,
The bag body (21) has a longitudinal direction extending in the longitudinal direction and a lateral direction intersecting with the longitudinal direction in a direction substantially perpendicular to the longitudinal direction. The longitudinal direction has an upper part and a lower part. A first side corresponding to the right side of the bag body (21) and a second side corresponding to the left side;
Forming an initial blood inlet (23) at the top of the bag body (21), forming an initial blood outlet (24) at the bottom of the bag body (21);
A first partition (P1) and a second partition (P2) are formed inside the bag body (21),
The first partition part (P1) and the second partition part (P2) are respectively located on the proximal end on the side close to the inlet (23) of the primary blood and on the outlet (24) side of the primary blood. With a distal end on the near side,
The first partition (P1) is formed so as to be along the substantially vertical direction of the bag body (21),
The second partition (P2) is formed so as to be along the substantially vertical direction of the bag body (21),
The proximal end of the first partition (P1) is formed near the top of the bag body (21) and not in contact with the top,
The distal end of the first partition (P1) is formed continuously from the lower part of the bag body (21),
The proximal end of the second partition (P2) is formed continuously on the upper part of the bag body (21),
The distal end of the second partition (P2) is formed so as not to contact the lower part of the bag body (21),
The first partition part (P1) and the second partition part (P2) partition the interior of the bag body (21) into a blood reservoir (S1) and an air reservoir (S2), and a blood passage (W1). Forming an air passage (W2),
An upper open part (O1) and an air reservoir (S2) are formed from the proximal end toward the distal end between the first partition part (P1) and the second side part of the bag body (21). And
Between the second partition part (P2) and the first side part of the bag body (21), from the proximal end toward the distal end, the blood passage (W1), the first lower opening part (O2 ′) )
An air passage (W2) and a second lower opening (O2) are formed between the first partition (P1) and the second partition (P2),
The blood inlet (23) communicates with the blood reservoir (S1) via the blood passage (W1) and the first lower opening (O2 ′),
The blood reservoir (S1) communicates with the air reservoir (S2) via the second lower opening (O2), the air passage (W2) and the upper opening (O1).
Blood collection with a closure means (C) capable of closing the blood passage (W1) and the air passage (W2) from the first side to the second side outside the bag body (21) Provide first stream removal bags (BE, BF).
[2] The present invention is a blood collection initial flow removal bag for storing initial flow blood collected from a blood donor,
A partition (P) is formed inside the bag body (21), and the bag body (21) is partitioned into a blood reservoir (S1) and an air reservoir (S2),
Forming an initial blood inlet (23), an initial blood outlet (24) and an air outlet (23 ') on the blood reservoir (S1) side of the bag body (21);
An air inlet (23 ″) is formed on the air reservoir (S2) side of the bag body (21),
Connecting the air outlet (23 ′) and the air inlet (23 ″) via a connecting tube (T7);
Blocking that can block the flow path of the tube (T2, T7) to the first blood introduction tube (T2) connected to the inlet (23) of the first blood of the bag body (21) and the connecting tube (T7). A blood collection initial flow removal bag (BH) equipped with means (C) is provided.
[3] The blood collection initial flow removal bag according to [1] or [2], wherein the blood reservoir (S1) has a volume substantially the same as a prescribed amount of blood to be collected. (BE, BF, BH).
[4]
[1] to [3] The blood collection initial flow in which the blood collection means to the external container is formed at the initial blood outlet (24) of the blood collection initial flow removal bag (BE, BF, BH) according to any one of [3] Provide removal set (1E, 1F, 1H).
[5]
In a blood bag (2) comprising a parent bag (4) for collecting blood and a plurality of child bags (5, 6),
The initial blood introduction tube (T2) is connected to the branch tube (13a) arranged in the middle of the blood collection tube (T1) to which the blood collection needle (8) is connected upstream, and the initial flow blood introduction tube (T2) A blood bag (2) to which the blood collection initial flow removal set (1E, 1F, 1H) described in any one of [1] to [4] is connected downstream is provided.

By configuring the blood collection initial flow removal bag and the blood collection initial flow removal set of the present invention as described above,
(1) The blood can be quickly sampled from the blood collection initial flow removal bag B without an unreasonable posture such as the operator bending down.
(2) When blood is collected in the vacuum blood collection tube, the air passage W2 formed in the bag body 21 does not move again to the blood reservoir S1 during the initial blood collection, so that the air is not moved again to the blood reservoir S1. In addition, even if the initial blood collection bag B is inverted, air is not sucked into the vacuum blood collection tube.
(3) It can be easily determined that the specified amount of blood to be collected in the blood collection initial flow removal bag B has been collected.
(4) After closing the blood passage W1 and the air passage W2 (initial flow blood introduction tube T2 and connection tube T7), the bag is sealed in the air reservoir S2 (air reservoir container S2 ′) no matter how the bag is handled. The trapped air does not flow back into the blood reservoir S1, and there is no fear that air is sucked into the vacuum blood collection tube during initial blood collection.

FIG. 1 is a schematic diagram of a blood collection initial flow removal set 1E, and FIG. 2 is a schematic diagram of a blood bag 2. 3 and 5 are schematic views of blood collection initial flow removal sets 1F and 1H showing another embodiment of FIG. FIG. 4 is a schematic diagram of a blood collection initial flow removal set 1G showing a reference example.
[Blood initial flow removal set 1E, 1F, 1G, 1H]
The blood collection initial flow removal set 1E collects the blood of the blood donor in the blood collection initial flow removal bag BE, BF, BG, BH at the time of blood collection, etc., so that bacteria or the like existing in the skin of the needle puncture site or subcutaneous In this case, the initial blood collected in the blood collection initial flow removal bag BE, BF, BG, BH is also used as blood for testing.
This blood collection initial flow removal set 1E, 1F, 1G, 1H includes blood collection initial flow removal bags BE, BF, BG, BH and blood collection means (for example, a blood collection tube holder 22 described later), for example, the blood bag of FIG. 2 is connected to the downstream (end portion) of the initial blood introduction tube T2 connected to the branch tube 13a disposed in the middle of the blood collection tube T1.

[Bleeding initial removal bag BE, BF]
In the blood collection initial flow removal bags BE and BF, the initial flow blood collected from the blood donor is stored.
The main body 21 of the blood collection initial flow removal bag BE, BF has a longitudinal direction extending in the longitudinal direction and a lateral direction intersecting the substantially perpendicular direction with respect to the longitudinal direction, and the longitudinal direction includes an upper part and a lower part. And the lateral direction has a first side corresponding to the right side of the bag body (21) and a second side corresponding to the left side.
In the upper part of the bag body 21, an inlet 23 for taking the initial blood to be collected into the bag body 21 is formed, and in the lower part of the bag body 21, an outlet 24 for taking out the collected blood is formed. .
The first partition P1 and the second partition P2 are formed in the bag body 21 by means such as heat welding.
The first partition P1 and the second partition P2 have a proximal end on the side close to the initial blood inlet 23 and a distal end near the initial blood outlet 24 side.
The 1st partition part P1 and the 2nd partition part P2 are formed so that the substantially vertical direction of the bag main body 21 may be followed.
The proximal end of the first partition P1 is formed near the top of the bag body 21 and does not contact the top, and the distal end of the first partition P1 is continuous with the bottom of the bag body 21. And formed.
The proximal end of the second partition part P2 is formed continuously on the upper part of the bag body 21, and the distal end of the second partition part P2 is formed so as not to contact the lower part of the bag body 21.
The first partition P1 and the second partition P2 divide the interior of the bag body 21 into a blood reservoir S1 and an air reservoir S2, and a blood passage W1 and an air passage W2.
An air passage W2 formed between the first partition portion P1 and the second partition portion P2, and a blood passage W1 formed between the second partition portion P2 and the second side portion of the bag body 21 are separated from the bag body. 21 is closed by the closing means C from the outside.
Between the 1st partition part P1 and the 2nd side part of the bag main body 21, the upper open part O1 and the air reservoir S2 are formed toward the distal end from the proximal end.
Between the second partition portion P2 and the first side portion of the bag body 21, a blood passage W1 and a first lower open portion O2 ′ are formed from the proximal end toward the distal end, and the first partition portion P1 is formed. An air passage W2 and a second lower open portion O2 are formed between the first partition portion P2 and the second partition portion P2.
The blood inlet 23 communicates with the blood reservoir S1 via the blood passage W1 and the first lower opening portion O2 ′, and the blood reservoir S1 passes through the second lower opening portion O2, the air passage W2 and the upper opening portion O1, It communicates with the air reservoir S2.
A closing means C capable of closing the blood passage W1 and the air passage W2 is attached to the outside of the bag body 21 from the first side portion to the second side portion.
The closing means C may be anything, for example, a clamp, a lever, etc., as long as it can be attached to the outside of the bag body 21 and can close the air passage W2 and the blood passage W1 with external pressure.
The obstruction means C is intended to reduce the blood collection rate when the blood reaches a predetermined amount before obstruction and prevent excessive collection of blood, and after the obstruction, the air once moved to the air reservoir S2 is used in the vacuum blood collection tube holder. It is attached for the purpose of preventing backflow when the sample is collected into the vacuum blood collection tube.

In the blood collection initial flow removal bag BE illustrated in FIG. 1, the first partition P <b> 1 and the second partition P <b> 2 are formed in a substantially vertical direction of the bag body 21.
The blood collection initial flow removal bag BF illustrated in FIG. 3 is formed by forming the first partition P1 and the second partition P2 close to each other and narrowing the air passage W2 therebetween. That is, the upper part of the first partition P1 is formed in an oblique direction from the middle (these are called bent portions R ′), and further extended in the vertical direction (downward) from the terminal portion of the bent portion R ′.
By narrowing the air passage W2, it is easier to close the air passage W2 than when it is formed wide, and the closing means C can be made compact.
As described above, the inside of the bag body 21 is divided into the blood reservoir S1 and the air reservoir S2.
During the first partition portion P1 and the second partition portion P2, to form the upper opening O1 and the second lower opening O2, first lower opening between the second partition portion P2 and the bag body 21 side O2 ′ Is formed.
When the initial blood is stored in the blood reservoir S1 of the empty bag body 21, the blood passes through the blood passage W1 and is stored in the blood reservoir S1. Blood passage W1 reliably guides blood to blood reservoir S1 and prevents blood from entering air passage W2 prior to air.
The air in the blood reservoir S1 is stored in the air reservoir S2 via the lower opening O2, the air passage W2, and the upper opening O1.
The width of the air passage W2 is preferably set to about 2 to 5 mm.

If the width of the air passage W2 is too narrow, there is a possibility that the air cannot smoothly move to the air reservoir S2 when blood is collected, and conversely if the air passage W2 is too wide, the air is surely collected. This is not preferable because the air that cannot be moved to S2 and is difficult to close by the closing means C and that has once moved to the air reservoir S2 may flow back to the vacuum blood collection tube 22 from the vacuum blood collection tube holder 22.
Further, the upper opening O1 (non-welded portion) of the first partition P1 is preferably set to about 2 to 5 mm for the same reason as the setting of the width of the air passage W2.
In addition, it is preferable to form the air reservoir S2 sufficiently wide, because the elasticity of the bag or air during blood collection does not cause a force to push back the inflowing blood and the possibility of insufficient blood collection is reduced.
Furthermore, by designing and forming the volume of the blood reservoir S1 so as to be substantially the same as the prescribed amount of blood to be collected, when the blood is full (full) in the blood reservoir S1, At the moment of overflowing into the air reservoir S2, it can be easily confirmed that the specified amount has been reached.

[Blood collection means in external container]
As a means for collecting blood collected in the initial blood collection bag B into an external container for examination or the like, a vacuum blood collection tube holder 22 or a tube with a connector (a connector is connected to the tube tip) at the outlet 24 of the bag body 21. May be formed. In short, anything can be used as long as blood can be collected in an external container.
For example, when a vacuum blood collection tube holder 22 as shown in FIG. 1 is employed as a specific means for collecting blood in an external container, for example, a first blood collection needle 25 is attached to the outlet 24, and the collection needle 25 A vacuum blood collection tube holder 22 is attached to the outer periphery of the tube. The collection needle 25 is covered with a sheath 26.
After collecting blood in the blood reservoir S1 of the bag body 21, a vacuum blood collection tube (not shown) is inserted into the vacuum blood collection tube holder 22, and the blood in the bag body 21 is collected in the vacuum blood collection tube.

[Blood bag 2]
For example, as shown in FIG. 2, the blood bag 2 includes a parent bag 4, a blood collection initial flow removal set 1, a blood filter 3, a first child bag 5, a second child bag 6, and a red blood cell storage solution containing bag 7. .
A blood collection tube T1 is connected upstream of the parent bag 4. A blood collection needle 8, a branch pipe 13a, and a flow path blocking means 12 are connected and arranged from the tip (upstream) to the middle of the blood collection tube T1. A blood collection initial flow removal set 1E is connected to the branch pipe 13a via a first blood introduction tube T2 (with a clamp 11 attached in the middle).
As illustrated in FIG. 1, the channel closing means 12 may be a communication piece 12 (one that partially breaks and opens the liquid channel) disposed inside the blood collection tube T <b> 1, and is illustrated in FIG. 1. The clamps 11a, 11b, and 11c that are attached to the outside of the tubes T1, T2, and T3 and can open and close the liquid flow path by opening and closing the tubes may be used.
Further, the blood filter 3 and the first child bag 5 are connected to the downstream of the parent bag 4 via a connecting tube T3. Further, the first child bag 5 is connected to the second child bag 6 and the red blood cell storage solution containing bag 7 through the connection tube T4, the branch tube 13b, and the connection tubes T5 and T6.
The parent bag 4 and the erythrocyte storage solution-containing bag 7 include, for example, an anticoagulant or an erythrocyte storage solution such as an ACD solution, a CPD solution, or a MAP solution for preventing or storing blood coagulation during blood collection or transfusion storage. Is housed.

  As a material constituting the initial blood collection bag BE or the like and the bags of the blood bag 2, for example, a flexible synthetic resin such as polyvinyl chloride or polyolefin is used.

[Usage example of blood collection initial flow removal set 1E]
(1) The first-stream blood collected from the supplier passes from the blood collection needle 8 punctured to the donor to the blood reservoir S1 through the branch tube 13a and the first-stream blood introduction tube T2, through the blood passage W1 of the bag body 21. Stored. As the blood is stored, the air in the blood reservoir S1 is driven by the blood, and is stored in the air reservoir S2 through the lower opening O2, the air passage W2, and the upper opening O1.
After the air is stored in the air reservoir S2, the air passage W2 and the blood passage W1 are closed from the outside of the bag body 21 by the closing means C, so that the air in the air reservoir S2 can be more reliably contained in the air reservoir S2. It can be contained inside.
(2) When the collection of the initial blood reaches a specified amount, the clamp 11a is closed to block the flow of blood to the blood collection initial flow removal bag B, and the communication piece 12 is broken to the parent bag 4. Stores blood.
(3) On the other hand, the blood stored in the blood reservoir S1 of the bag body 21 is collected from the vacuum blood collection tube holder 22 connected to the outlet 24 of the bag body 21 to the vacuum blood collection tube. At that time, even if the operator performs the sampling operation to the vacuum blood collection tube by inverting the blood collection initial flow removal bag B while keeping the standing posture in an easy posture without bending or squatting, it is stored in the air reservoir S2. The air does not enter the blood reservoir S1 again through the upper opening portion O1, the air passage W, and the lower opening portion O2, and therefore air does not enter the vacuum blood collection tube.

  The blood collection initial flow removal bags BE and BF are not limited to the forms illustrated in the above description and FIGS. 1 and 3. In short, the width of the air passage W2, the upper opening portion O1 (non-welded portion) of the first partition portion P1, the lower opening portion O2 (non-welding portion) and the lower opening portion O2 ′ (non-welding portion) of the second partition portion P2. The size (length, width), etc. is such that when the initial blood is stored in the blood reservoir S1 of the empty bag body 21, the air in the blood reservoir S1 is opened to the lower opening O2, the air passage W, and the upper opening. The air stored in the air reservoir S2 is stored in the air reservoir S2 through the portion O1, and the blood stored in the air reservoir S2 is contained in the blood reservoir S1 through the upper open portion O1, the air passage W2, and the lower open portion O2. Any form that does not flow backward is acceptable.

Other reference examples (FIG. 4) and examples (FIG. 5) of the blood collection initial flow removal bags BE, BF (blood collection initial flow removal sets 1E, 1F) illustrated in FIGS. 1 and 3 will be described in detail below.

[Blood sampling initial removal bag BG]
The blood collection initial flow removal bag BG (blood collection initial flow removal set 1G) illustrated in FIG. 4 is compared with the blood collection initial flow removal bags BE and BF (blood collection initial flow removal sets 1E and 1F) illustrated in FIGS. Thus, the partition portions P1 and P2 inside the bag body 21 are eliminated, and an air reservoir S2 ′ is connected via a connecting tube T7 instead.
In the initial blood collection bag BG, the initial blood is collected inside the bag body 21, and the air inside the bag body 21 is expelled to the air reservoir S2 ′ via the outlet 23 ′, the connecting tube T7, and the inlet 23 ″. As illustrated in FIG. 4, the positions close to the bag main body 21 and the air reservoir S <b> 2 ′ of the initial blood introduction tube T <b> 2 and the connection tube T <b> 2 are closed by the closing means C, respectively. As a result, the air in the air reservoir S2 ′ can be more reliably contained in the container S2 ′.

[Blood initial removal bag BH]
The blood collection initial flow removal bag BH (blood collection initial flow removal set 1H) illustrated in FIG. 5 is the bag body 21 and the air reservoir S2 ′ of the blood collection initial flow removal bag BG (blood collection initial flow removal set 1G) illustrated in FIG. Are integrated.
More specifically, a partition P is formed inside the bag body 21, and the bag body 21 is partitioned into a blood reservoir S1 and an air reservoir S2.
An initial blood inlet 23, an initial blood outlet 24, and an air outlet 23 'are formed on the blood reservoir S1 side of the bag body 21, and an air inlet 23 "is formed on the air reservoir S2 side. These air outlet 23 ′ and inlet 23 ″ are connected via a connecting tube T7, and the initial blood flow connected to the initial blood inlet 23 of the bag body 21 is similar to the blood collection initial flow removal bag BG of FIG. A closing means C capable of closing the blood flow introduction tube T2 and the connecting tube T7 is attached.

  It is preferable that each blood collection initial flow removal bag BE, BF, BG, BH is designed to have a prescribed blood collection amount when the blood reservoir S1 is full (full). After the blood passage W1 and the air passage W2 are once closed by simultaneously closing the blood passage W1 (tube T2) and the air passage W2 (tube T7) with the closing means C (or they may be closed separately). No matter how the bag is handled, the air trapped in the air reservoir S2 (air reservoir S2 ′) does not flow back into the blood reservoir S1, and the vacuum blood collection tube ( There is no concern about inhaling air (not shown).

An example of the closing means C will be described.
As an example of the closing means C, a clamp 31 illustrated in FIG. 6 is used.
The clamp 31 forms two clamping parts (a first clamping part 33 and a second clamping part 34) on both sides of the hinge part 32, and the other clamping part is provided at one end of the clamping parts 33 and 34. An engaging portion 36 of the end portion 35 of 33, 34 is formed.
A mounting groove 37 for the tubes T2 and T7 may be formed inside the hinge portion 32.
In short, the closing means C has two holding portions (first holding portion 33 and second holding portion 34) that can close the blood passage W1 and the air passage W2 of the bag body 21 and the flow paths of the tubes T2 and T7. Anything is fine. The hinge part 32, the engaging part 34, the mounting groove 36, and the like may be optionally formed.

[Usage example of closing means C (clamp 31)]
In the blood collection initial flow removal bags BE and BF of FIGS. 1 and 3, the bag body 21 is sandwiched between the two sandwiching portions (the first sandwiching portion 33 and the second sandwiching portion 34), and the bag body 21 is externally attached. In order to close the blood passage W1 and the air passage W2 and maintain the closed state, for example, the end portion of the first clamping portion 33 is engaged with the engaging portion 36.
In the blood collection initial flow removal bags BG and BF of FIGS. 4 and 5, the tubes T2 and T7 are sandwiched between the two clamping parts (the first clamping part 33 and the second clamping part 34). In order to close the flow path and maintain the closed state, for example, the end portion of the first clamping portion 33 is engaged with the engaging portion 36. When there is a tube mounting groove 36, the clamp 31 can be mounted on either the tube T2 or T7.

Schematic of blood collection initial flow removal set 1E (blood collection initial flow removal bag BE) Schematic diagram of blood bag 2 Schematic of the blood collection initial flow removal set 1F (blood collection initial flow removal bag BF) showing another embodiment of FIG. Schematic of the blood collection initial flow removal set 1G (blood collection initial flow removal bag BG) showing another reference example of FIG. Schematic diagram of the blood collection initial flow removal set 1H (blood collection initial flow removal bag BH) showing another embodiment of FIG. Schematic showing an example of closing means

Explanation of symbols

1E, 1F, 1G, 1H
Blood collection initial flow removal set 2 Blood bag BE, BF, BG, BF Blood collection initial flow removal bag 3 Blood filter 4 Parent bag 5 First child bag 6 Second child bag 7 Red blood cell storage solution bag 8 Blood collection needle 10 Needle cover 11a, 11b, 11c Clamp 12 Communication piece 13a, 13b Branch tube 21 Bag body 22 Vacuum blood collection tube holder 23 (primary blood) inlet 23 '(air) outlet 23 "(air) inlet 24 (primary blood) Outlet 25 (Initial blood) collection needle 26 Sheath S1 Blood reservoir S2 Air reservoir S2 ′ Air reservoir P1 First partition P2 Second partition P Partition O1 Upper open portion O2 ′ First lower open portion
O2 second lower opening
W1 Blood passage W2 Air passage R ′ Bending portion T1 Blood collection tube T2 Initial flow blood introduction tube T3, T4, T5, T6, T7 Connection tube C Blocking means 31 Clamp 32 Hinge 33 First clamping portion 34 Second clamping portion 35 End portion 36 Engaging portion 37 Tube mounting groove

Claims (5)

  1. A blood collection initial flow removal bag for storing initial blood collected from a blood donor,
    The bag body (21) has a longitudinal direction extending in the longitudinal direction and a lateral direction intersecting with the longitudinal direction in a direction substantially perpendicular to the longitudinal direction. The longitudinal direction has an upper part and a lower part. A first side corresponding to the right side of the bag body (21) and a second side corresponding to the left side;
    Forming an initial blood inlet (23) at the top of the bag body (21), forming an initial blood outlet (24) at the bottom of the bag body (21);
    A first partition (P1) and a second partition (P2) are formed inside the bag body (21),
    The first partition part (P1) and the second partition part (P2) are respectively located on the proximal end on the side close to the inlet (23) of the primary blood and on the outlet (24) side of the primary blood. With a distal end on the near side,
    The first partition (P1) is formed so as to be along the substantially vertical direction of the bag body (21),
    The second partition (P2) is formed so as to be along the substantially vertical direction of the bag body (21),
    The proximal end of the first partition (P1) is formed near the top of the bag body (21) and not in contact with the top,
    The distal end of the first partition (P1) is formed continuously from the lower part of the bag body (21),
    The proximal end of the second partition (P2) is formed continuously on the upper part of the bag body (21),
    The distal end of the second partition (P2) is formed so as not to contact the lower part of the bag body (21),
    The first partition part (P1) and the second partition part (P2) partition the interior of the bag body (21) into a blood reservoir (S1) and an air reservoir (S2), and a blood passage (W1). Forming an air passage (W2),
    An upper open part (O1) and an air reservoir (S2) are formed from the proximal end toward the distal end between the first partition part (P1) and the second side part of the bag body (21). And
    Between the second partition part (P2) and the first side part of the bag body (21), from the proximal end toward the distal end, the blood passage (W1), the first lower opening part (O2 ′) )
    An air passage (W2) and a second lower opening (O2) are formed between the first partition (P1) and the second partition (P2),
    The blood inlet (23) communicates with the blood reservoir (S1) via the blood passage (W1) and the first lower opening (O2 ′),
    The blood reservoir (S1) communicates with the air reservoir (S2) via the second lower opening (O2), the air passage (W2) and the upper opening (O1).
    A closing means (C) capable of closing the blood passage (W1) and the air passage (W2) from the first side portion to the second side portion is attached to the outside of the bag body (21).
    A blood collection initial flow removal bag (BE, BF).
  2. A blood collection initial flow removal bag for storing initial blood collected from a blood donor,
    A partition (P) is formed inside the bag body (21), and the bag body (21) is partitioned into a blood reservoir (S1) and an air reservoir (S2),
    Forming an initial blood inlet (23), an initial blood outlet (24) and an air outlet (23 ') on the blood reservoir (S1) side of the bag body (21);
    An air inlet (23 ″) is formed on the air reservoir (S2) side of the bag body (21),
    Connecting the air outlet (23 ′) and the air inlet (23 ″) via a connecting tube (T7);
    Blocking that can block the flow path of the tube (T2, T7) to the first blood introduction tube (T2) connected to the inlet (23) of the first blood of the bag body (21) and the connecting tube (T7). A blood collection initial flow removal bag (BH), which is equipped with the means (C).
  3. The blood collection initial flow removal bag (BE) according to claim 1 or 2 , wherein the volume of the blood reservoir (S1) is formed to be substantially the same as a prescribed amount of blood to be collected. , BF, BH).
  4. The blood collection means for the external container is formed at the outlet (24) of the initial blood of the initial blood collection bag (BE, BF, BH) according to any one of claims 1 to 3 . A blood collection initial flow removal set (1E, 1F, 1H).
  5. In a blood bag (2) comprising a parent bag (4) for collecting blood and a plurality of child bags (5, 6),
    The initial blood introduction tube (T2) is connected to the branch tube (13a) arranged in the middle of the blood collection tube (T1) to which the blood collection needle (8) is connected upstream, and the initial flow blood introduction tube (T2) A blood bag (2), wherein the blood collection initial flow removal set (1E, 1F, 1H) according to any one of claims 1 to 4 is connected downstream.
JP2006294611A 2006-10-30 2006-10-30 Blood collection initial flow removal bag, blood collection initial flow removal set and blood bag Expired - Fee Related JP4879704B2 (en)

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JP5368466B2 (en) * 2008-10-10 2013-12-18 川澄化学工業株式会社 Blood collection initial flow removal bag, blood collection initial flow removal set and blood bag
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US7824343B2 (en) * 1999-07-29 2010-11-02 Fenwal, Inc. Method and apparatus for blood sampling
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WO2013137361A1 (en) * 2012-03-14 2013-09-19 テルモ株式会社 Container for testing blood and blood sampling instrument
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JPWO2013137359A1 (en) * 2012-03-14 2015-08-03 テルモ株式会社 Laboratory blood container and blood collection device

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