TWI379664B - Device and method for estimating physical age index by measuring bioimpedance phase angle - Google Patents

Device and method for estimating physical age index by measuring bioimpedance phase angle Download PDF

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TWI379664B
TWI379664B TW97140366A TW97140366A TWI379664B TW I379664 B TWI379664 B TW I379664B TW 97140366 A TW97140366 A TW 97140366A TW 97140366 A TW97140366 A TW 97140366A TW I379664 B TWI379664 B TW I379664B
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phase angle
value
bioimpedance
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age
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TW97140366A
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Chinese (zh)
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TW201016194A (en
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Kun Chang Hsieh
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Charder Electronic Co Ltd
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1379664 _______ 101年8月q日修正替換頁 六、發明說明: 【發明所屬之技術領域】 本發明係為一種人體量測生物阻抗相位角估測生理年 齡指標之裝置與方法’尤指一種直接量測受測者之生物阻抗 相位角估測等人體資訊,其中’可直接經由原受測者之生物 阻抗相位角估測與相位角配合於相位角評估平台上產生各 項比對之對照值,以使受測者可有效快速的得知自己生理年 齡與實驗統計之標準值差距為何者。 【先前技術】 按生物阻抗法分析(Bioelectrical Impedance Analysis)對於醫學電阻抗的研究最早始於μ世紀末,生 物阻抗技術是利用生物組織與器官的電性特性(阻抗、介電 常數等)及其變化提取人體生理、病理狀況相關的生物醫學 訊息的非侵人式檢測技術。通常是借助於皮膚表面的電極系 統向受測者發射-微小較流電流或電壓,檢測相應的阻抗 及其變化情況’然後根據不同的應用目的,獲取相關的生理 與病理訊息。這種技術具非侵入、便宜、安全、 宝 ::單等特點,醫護人員與病人接易於接受,具有二 生物電阻抗分析法综合阻抗法與全身水量法 能夠導電的性質給受測對象 彻人體 傲h的電流,改變電流的頻 1379664 丨❶1年8月巧日修正替換頁 率使其在人體中的穿透深度發生變化,人體^身既有卩£^^ 有谷性,所以不同頻率的電流穿透人體組織的深度不同。許 夕的研究中,當電流頻率在較高的頻率上時電流可穿透人體 細胞膜,此時或在此之後繼續加大電流頻率所測量的阻抗值 及為人體全身阻抗。當較低頻率時電流僅在細胞外通路中傳 播,這時測得的電阻值是人體細胞外阻抗,人體中的的水分 主要包括細胞内液與細胞外液。人體中的脂肪由於其含水量 極小被認為是絕緣體,所以;當電流施加於人體後,將隨人 體内的水分遍及全身,作為人體内唯一的導電物質,人體的 電阻值將主要由人體中的水量決定。 關於生物阻抗相位角的研究應用上,〇Uver曾針對健康 受測者、醫院病人與肝硬化的病人,針對其生物組抗相位角 差異進行研究比對。Lukaski對於懷孕婦女初、中、末與生 產過後時間之相位角進行研究。Bi*ab〇se-Si!va分別對於居 住於都市832、1135名男女進行其年齡與相位角之關係研 九Marra對於有厭食症的女性以相位角進行基礎代謝率 (Basal Metabolic Rate__預測關係研究。⑶池等人對 於不同肥胖程度的老人,進行年齡、肥胖程度、相位角關係 之研究。除此之外關於相位角在人體測量臨床上的應用尚有 許多應研究’包含在HIV的觀測、肺癌(Lung⑽㈣、血 液透析(hem〇dialysis)、嚴重疾病(Critically in)等等都 有其應用。 5 山” L A Li01年8月η日修正替換頁 由L上的文獻回射得知,生物阻抗法- 大都均是針對某些特定族群或病患,在上述所提及的研究 中’可清楚歸納出相㈣的減小,與健康狀況的惡化有著正 相關關係,接紐著年齡的增加,有著隨之減少的趨勢,故 如以受測者相對相位角的增加與減少,為判斷受測者或者病 患的生理年齡狀態之重要指標。此外;生物阻抗法近年來多 用於人體組成成分的分析與推估,相㈣是否與肥胖有何關 係,在現有的研究與專利方面,應較為少見。 生物阻抗法係將人體細胞浸於導電的細胞外液 =二二擇性^些離子的細胞膜包裹著導電的細 胞内液組成’細胞外液、細胞⑽的電學性質接近 而細胞膜則可能等效電容。因此人體料效電路應當是 =:t:聯電路。為此’人_τ多種的等效 示由的三元件等效電路模型則如第1圖所 /' Θ Rl ' Re與C分別為細胞内液電阻、^ 液電阻與細胞膜電容,則其總阻抗可以表示為:胞外 Z = Re / / (ZC + Ri ) 生物阻抗刀析的基本原理在於生物組織對外加電 2不同導電作用,當在人體表面加一固定頻率的^ 含水膨X上的肌肉域是良好導體 了電 脂肪組織近似絕绫俨m 向3水較少的 纖、,邑緣體,因此通過測出阻抗值,配合 析’可以估算出身體組成成分,生物阻抗分析用於人= 1379664 1〇1年8月日修正替換頁 勿析是假设人體為一圓柱的幾何外型,生物組織中的水與電 解質的分佈均勻且值定。根據Cole~Cole理論,RC三元件 生物阻抗模型在複平面上的阻抗執跡圖是在第四象限的一 段圓弧’如第2圖騎,這可解釋為等效電路1Mi與C串 聯的結果。 而目刖對於大量健康人士進行之生物阻抗法相位角之 研九刀別有Anja與Antonio等人,其中分別對國地區健康 人士、非拉丁裔白人(n〇n-Hispanic white)、非拉丁裔黑人 (non-Hispanic black)與墨西哥裔美國人(Mexican1379664 _______ Correction and replacement page of August, 2010, Q. Description of the invention: [Technical field of invention] The present invention relates to a device and method for estimating a physiological age index of a bioimpedance phase angle of a human body, especially a direct quantity The human body information such as the bioimpedance phase angle estimation of the subject is measured, wherein the bioacoustic phase angle estimation and the phase angle of the original subject are directly matched with the phase angle evaluation platform to generate comparison values of the comparisons. In order to enable the subject to quickly and effectively know the difference between his physiological age and the standard value of the experimental statistics. [Prior Art] According to Bioelectrical Impedance Analysis, the study of medical electrical impedance begins at the end of the μ century. Bioimpedance technology uses the electrical properties (impedance, dielectric constant, etc.) of biological tissues and organs and their changes. A non-invasive detection technique for extracting biomedical information related to physiological and pathological conditions of the human body. Usually, the electrode system on the surface of the skin is used to emit a small current or voltage to detect the corresponding impedance and its changes. Then, relevant physiological and pathological information is obtained according to different application purposes. This technology has the characteristics of non-invasive, cheap, safe, and treasure:: single, medical personnel and patients are easy to accept, with two bioelectrical impedance analysis method, comprehensive impedance method and whole body water method can conduct electricity to the test object to the human body. The current of the proud h, the frequency of changing the current is 1396664. In August 1st, the corrected replacement page rate is changed to make the penetration depth in the human body change. The human body has both ^£^^ gluten, so different frequencies The depth at which current penetrates human tissue is different. In Xu Xi's research, when the current frequency is at a higher frequency, the current can penetrate the human cell membrane, and at this time or after that, the impedance value measured by the current frequency is continuously increased and the whole body impedance is taken. When the current is transmitted in the extracellular pathway at a lower frequency, the measured resistance value is the extracellular impedance of the human body, and the water in the human body mainly includes the intracellular fluid and the extracellular fluid. The fat in the human body is considered to be an insulator because of its extremely small water content. Therefore, when the current is applied to the human body, the water in the human body will spread throughout the body. As the only conductive substance in the human body, the resistance value of the human body will be mainly from the human body. The amount of water is determined. Regarding the research and application of bioimpedance phase angle, 〇Uver has compared the anti-phase angle differences of healthy subjects against healthy subjects, hospital patients and patients with cirrhosis. Lukaski studied the phase angles of pregnant women at the beginning, middle and end of the day and after birth. Bi*ab〇se-Si!va has a relationship between age and phase angle for 832 and 1135 men and women living in cities respectively. Studying Marra has a basal metabolic rate (Basal Metabolic Rate__ predictive relationship) for women with anorexia. Research. (3) Chi et al. studied the relationship between age, obesity, and phase angle for elderly people with different degrees of obesity. In addition to the clinical application of phase angle in anthropometrics, there are still many studies that should be studied. Lung cancer (Lung (10) (four), hemodialysis (hem dialysis), severe disease (Critically in), etc. have their application. 5 "Lan" LA Li August η day correction replacement page is known from the literature on L, retrospective Impedance method - most of them are for certain ethnic groups or patients. In the above mentioned studies, the reduction of phase (4) can be clearly summarized, and it is positively correlated with the deterioration of health status. There is a tendency to decrease accordingly, so if the relative phase angle of the subject is increased or decreased, it is an important indicator for judging the physiological age state of the subject or the patient. In recent years, the impedance method has been mostly used for the analysis and estimation of human body components, and whether phase (4) has a relationship with obesity. It should be relatively rare in existing research and patents. Bioimpedance method immerses human cells in conductive extracellular fluid. = two or two selective ion membranes wrapped with conductive intracellular fluid composition 'extracellular fluid, cells (10) electrical properties are close to the cell membrane may be equivalent capacitance. Therefore, the human body effect circuit should be =: t: joint circuit For this reason, the equivalent three-element equivalent circuit model of 'human_τ is as shown in Fig. 1' Θ Rl 'Re and C are intracellular liquid resistance, liquid resistance and cell membrane capacitance, respectively. The total impedance can be expressed as: extracellular Z = Re / / (ZC + Ri) The basic principle of bioimpedance knife analysis is that the biological tissue is externally powered by 2 different conductive effects when adding a fixed frequency to the surface of the human body. The muscle domain is a good conductor. The electrical fat tissue is approximately the same as the fiber with less water, and the rim body. Therefore, by measuring the impedance value, the body composition can be estimated by using the analysis, and bioimpedance analysis is used. people = 1379664 1 8 1 8 修正 修正 修正 修正 是 是 是 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设 假设The impedance trace of the model on the complex plane is a circular arc in the fourth quadrant, as shown in Figure 2, which can be interpreted as the result of the concatenation of the equivalent circuit 1Mi and C. There are also Anja and Antonio in the phase angle of the impedance method. Among them are healthy people in the country, non-Latin whites, non-Hispanic blacks and Mexicans. American (Mexican

American)進行研究’使相位角研究的結果更為可信度提 同’則相同測试環境或者大量的的取樣數就變得非常重要, 惟目刖對於此-研究之應用,仍屬少數。 【發明内容】 有鑑於斯’本案發明人乃經詳思細索,並積多年從事各 種里測人體各項指數之產品與技術研發的經驗,終於開發出 種人體量測&物阻抗相位角估測生理年齡指標之裝置與 方法。 本發月之目的在於提供一種人體量測生物限抗相位角 估測生理年齡指標之裂置與方法,其主要係藉由—相位角評 估平口以及其對應之相位角模組產生,經由該相位角評估平 σ内之相位角資料庫透過資料之建立,域定對應之模組, 7 1379664 日修正替換頁 經簡單量測受測者的阻抗值與相位角’即可由模組中得到才#、 準之相位角、生物阻抗相位角估測與生理年齡等數值,並經 比對整合後,即可獲得對照值、標準值以及參考值,並於建 議資料庫中取得相關建議之資料’而產生表單,而達到快速 量測以及簡單取得受測者目前生理狀態數值之目的者。 本發明之目的係在於提供一種人體量測生物卩且抗相位 角估測生理年齡指標之裝置與方法,而其模組之建立,主要 係經過大量健康人士之進行過生物阻抗測量與資料庫建立 與統計研究,並將其測量群組分別以身體質量指數為區分等 級分成多個群組,每個群組又分別以年齡分成次群組詳細 的將各個群組與次群組的對應的生物電阻值 ^Resistance)、生物電抗值Xc(Reactance)其平均值與標準 f發表於該研究上,其關係係經由統計方法釐清其關係^並 稭以為估測人體生理年齡之方法與機制。 該方法之流程係包括: 輸入資料:輸入受測者的身高、 料’包括:人種膚色等資料; 選擇比對標準模組:經相 組:經相位角評估孚台American) conducting research 'to make the results of the phase angle study more credible' is the same test environment or a large number of samples becomes very important, but the application is still a minority for this application. [Invention] In view of the fact that the inventor of this case has carefully studied and accumulated years of experience in product and technology research and development of various human body indices, he has finally developed a human body measurement & impedance phase angle. Apparatus and method for estimating physiological age indicators. The purpose of this month is to provide a method and method for estimating the physiological age index of the human body measurement biological limit phase angle estimation, which is mainly generated by the phase angle evaluation flat port and its corresponding phase angle module, through which the phase is generated. The angle angle database in the angle evaluation σ is established through the data, and the corresponding module is determined. 7 1379664 The corrected replacement page is simply measured by the measured impedance value and phase angle of the subject. , the quasi-phase angle, the bioimpedance phase angle estimation and the physiological age, etc., and after comparison and integration, the control value, the standard value and the reference value can be obtained, and the relevant suggestion data can be obtained in the suggestion database. The form is generated, and the person who achieves the rapid measurement and simply obtains the current physiological state value of the subject is obtained. The object of the present invention is to provide a device and a method for measuring a biological body and measuring a physiological age index against a phase angle, and the establishment of the module is mainly carried out by a large number of healthy persons to perform bioimpedance measurement and database establishment. And statistical research, and the measurement group is divided into multiple groups according to the body mass index, and each group is divided into the subgroup by age, and the corresponding creatures of each group and the subgroup are detailed. Resistance value (Resistance), bioreactor value Xc (Reactance) The average value and standard f are published in the study, and the relationship is based on statistical methods to clarify the relationship ^ and straw as a method and mechanism for estimating the physiological age of human body. The flow of the method includes: input data: input the height and material of the subject' includes: data such as ethnic color; selection standard module: phase group: evaluation of phase angle

、相位角等數值; $剛受測者之比對數 值:藉由針對於人 體重與年齡或其他資 之相位資料庫建 生物阻抗相位角 體之四肢設置電 8 1379664 月日修正替換頁 極’經電極之發射與接收電極對透過單晶片了 控制’分別量測對應電阻抗值以及各項的對照值,其中,包 括:對照生理年齡、對照相位角以及對照生物阻抗相位角估 測,並於該相位角評估平台中經由該對照值得出相對之參考 值; 比對:於該相位角評估平台中進行比較,使對照值參 考值與標準值等數值進行標準差分析; 整合··將該標準差内容與建議資料庫内之資料比對整 合; ' 產生表單:將前述建議與數值列表,受測者可輕易的由 • 表單得知該相位角、生物阻抗相位角估測與生理年齡與標準 值間之差異。 而前述之模組之建立流程係包括·· 量測:針較測者量測阻抗值、生物阻抗相位角估測以 及相位角等數值,運用生物阻抗法進行量測,分別得到前述 各數值内容; ㈣相位角評估平台··針對各受測者之年齡、身體狀 態 '性別㈣㈣構出不同之標準模組,並形成以相位角、 年齡與生物阻抗相位角估測等條件予以統計分析形成相位 角S平估平台以及相位角資料庫; 形成資料庫:於不同條件之標準模組部份,以累積受測 者之方式予以統計分析並統一標準化形成各模組之標準值 9 1379664 而予以記錄者。 101年修正替拖頁 以藉由該準確之標準值内容,包括:電阻值、相位角、 生物阻抗相位角估測以及年齡或其他資料等資料庫配合量 測出各受測者各部份數值,直接形成一實際年齡以及生理年 齡等各項數值之差異性,以強化受測者各部份之異常,而達 到提供與建議受測者各項生理數值以及應對補救之内容者。 【實施方式】 說明之 有關本發明為達成上述目的,所採用之技術、手段及其 他之功⑵舉—較佳可行實施例並配合圖式詳細說明如 后,相k本發明上述之目的、特徵及其他之優點,當可由之 得一深人而㈣之瞭解,惟本發㈣摊―之實施例,容此 ::明之置測生物阻抗相位角估測生理年齡指 咖主㈣♦巾本發明之量測 ^ . 天慝理态11 ’中央處理器11主要連 :二角:料庫㈣及—建議資料庫㈣形成-相 ’而該中央處理器11另連接-電源 輸出裝置15、至少一 ^·λ壯aa 測器17,盆中,輪入裳置16以及複數個輪入感 相位角資料座Θ11即為—般的電腦之處理器, 性m係各標準模組之資料内容,包括:年齡、 體月匕狀況、人種、電阻值、生物阻抗相位角话測 Μ ^㈣㈣庫13則為各魏值欠缺 方法與内容者;該電源14則可為一般之電池電源亦可交流 電電源者;該輸出襄置15係為顯示褒置,包括:電腦之螢 輪入裝置16則可為鍵盤、或按鍵或觸控營幕,·輪入感 測器17則為接於受測者肢體上之電極對者。 忒相位角6乎估平台2〇係為前述之相位角資料庫η架構 成者》玄相位角评估平台2〇係為一相位角0與受測者之 年齡Age以及生物阻抗相位角估測BMI的關係形態之平台 者。 ° 其中,該量測方法3〇之流程係包括: 輸入貝料31 .受測者於前述之量測裝置1()的輸入裝置 16上輸入本身之資料包括:受測者的身高、體重、年齡、性 別與體能狀況等資料; ^擇比對標準模組32:藉由電腦_,以前述之 資料中,於相位角評估平台 有 相近於受測者之桿準模相山位角資料庫12選取最 铽皁模組’並取出該標準 值21,包括:相位角样 、、·^之谷項‘準 及電阻值標準值; 生物阻抗相位角估測標準值以 4者之比對數值33:藉由 體設置之量測裝置1()> & 野於受測者人體之肢 』发置10之各輸入感測器17 測者肢體之末端,量其電、可各別設於受 角估測,以形成對昭值 几 角以及生物阻抗相位 威I值22,該對照值22係包括:電阻抗值、 ^/9664 物阻抗相位祕測等指數之數 时17係為一電極對結構’透過量測裝置1〇之單晶片中央處 理:Π配合相位角資料庫12與建議資料庫13形成一相位 角=平台2〇 ’以使前述之各對照值22可經由該相位角評 估平〇 20之轉換形成前述各數值之參考值23。 比對34 :於該相位角評估平台2〇針對各標準值21、對 照值22以及參考值23進再行比對者; 整合35 :將前步驟中之值比對後,以各同質性之各數值 形成各別之標準差’進八建議資料庫13巾崎資料之搜尋, 使符口各項標準差之建議内容得以取出; 議資前述之各項數值以及經統計分析後由建 ^ +取得之魏内容共同列於同-表單上者; 装生理2予以取用’即可由該數值上之差異以及建議得知 其生理年齡狀態。 而^述之相㈣資料庫12結構予以有效的被建立, 該相位角資料庫12模組建立流程40係包括: 乂及相位s ^對又财$測阻抗值、生物阻抗相位角估測 述各^内谷,大量且不同的受測者進行量測; 建構相位角評估平台42: 態、性別等條件建構出不同之又"之年齡、身體狀 年齡與生物阻抗相位角估測等::且’並形成以相位角、 等條件予以統計分析形成相位 1379664 • . 日修正替換頁 角評估平台20以及相位角資料庫12 ; —~— 形成資料庫43:於不同條件之標準模組部份,以累積受 . 測者之方式予以統計分析並統一標準化形成各模組之標準 值而予以記錄者。 其中,該相位角評估平台20之模組化分析,係以統計 分析為之,若以各國人種為對象,其相位角Θ與受測者之年 齡Age以及生物阻抗相位角估測BMI的關係式如下: male : (Θ) =Clmale+C2male x Age+C3male x BMI Female : (^) = ClFemale+C2Female x Age +C3Femalex BMI 其中,C1-C6為統計分析所得係數,故前述之對照值& 可兩兩代入各標準模組中之關係式中,分別得出不同之參考 值23,經由對照值22與參考值23間之差異以及對照值^ 與^準值21之標準差,可得知,受測者之實況與標準 值或參考值相差之數值為何?,受測者即可經由該一相位角 評估平台20各關係式中獲得各項差值,關至建議資料庫 13選取對應之内容,而可由表單中輸出觀之者。 其中,藉由對照值22與標準值21間之差異可知,受測 者身體狀況與該巾之鱗相差H可㈣照值22 與參考值23之比對而得知各項數值可能變異之方向者。 综上所述’本案發明所揭露人體量測生物阻抗相位角估 13 1379664 101年8月q日修正替換頁 測生理年齡指標之裝置與方法,特殊之設計已『具有產業之 可利用性』應已毋庸置疑,除此之外,在本案創作所揭露出 的技術特徵,於申請之前並未曾見於諸刊物,亦未曾被公開 使用,加之又具有如上所述功效增進之事實,是故,本發明 的『新穎性』及『進步性』均符合專利法規定,爰依法提出 創作專利之申請,析請惠予審查並早曰賜准專利,實感德便。 【圖式簡單說明】 第1圖係傳統生物阻抗法分析示意圖。 第2圖係傳統相位角示意圖。 第3圖係本發明量測裝置示意圖。 第4圖係本發明量測方法示意圖。 第5圖係本發相位角資料庫建制流程示意圖。 【主要元件符號說明】 量測裝置10 中央處理器11 相位角資料庫12 建議資料庫13 電源14 輸出裝置15 輸入裝置16 輸入感測器17 相位角評估平台20 標準值21 對照值22 參考值23 量測方法30 輸入資料31 選擇比對標準模組32 比對34 量測受測者之比對數值33 1379664 整合35 101年8月e日修正替換頁 產生表單36 模組建立流程40 • 量測41 建構相位角評估平台42 形成資料庫43 15Value of phase angle; value of $ just-tested pair: by setting the bio-impedance phase angle body for the human body weight and age or other phase data library 8 8379664 month correction correction page pole ' The transmitting and receiving electrode pairs of the electrodes are controlled by the single wafer to respectively measure the corresponding electrical impedance values and the comparison values of the respective values, including: the control physiological age, the control phase angle, and the control bioimpedance phase angle estimation, and In the phase angle evaluation platform, a relative reference value is obtained via the comparison; comparison: comparing in the phase angle evaluation platform, and performing standard deviation analysis on the reference value of the reference value and the standard value; The difference between the content and the information in the suggested database is integrated; 'Generate the form: the above list of suggestions and values, the subject can easily know the phase angle, bioimpedance phase angle estimation and physiological age and standard from the form The difference between the values. The above-mentioned module establishment process includes: · Measurement: the needle measures the impedance value, the bio-impedance phase angle estimation and the phase angle, etc., and uses the bio-impedance method to measure and obtain the above numerical contents respectively. (4) Phase angle evaluation platform ·························································································· Angle S flat evaluation platform and phase angle database; Forming a database: in the standard module part of different conditions, statistical analysis is carried out in the form of cumulative test subjects and standardized to form the standard value of each module 9 1379664 and recorded By. The 101-year revision is for the drag page to measure the values of each part of the subject by the accuracy of the standard value content, including: resistance value, phase angle, bio-impedance phase angle estimation, and age or other data. Directly form a difference between the actual age and the physiological age to enhance the abnormalities of the various parts of the subject, and to achieve the physiological values of the testee and the content of the remedy. EMBODIMENT OF THE INVENTION The present invention has been made in view of the above objects, the techniques, the means and the other functions (2), the preferred embodiments, and the detailed description of the present invention. And other advantages, when you can get a deep person and (4) understand, but the hair (four) booth - the embodiment, let this:: Ming measured bioimpedance phase angle estimated physiological age refers to the coffee master (four) ♦ towel invention The measurement of ^. Tianyi state 11 'Central processor 11 main connection: two corners: material library (four) and - suggested database (four) form - phase 'and the central processor 11 is connected - power output device 15, at least one ^·λstrong aa detector 17, in the basin, wheeled into the skirt 16 and a number of wheeled sense phase angle data Θ 11 is the general computer processor, the m is the standard module data content, including : age, body month, state, ethnicity, resistance value, bioimpedance phase angle measurement Μ ^ (4) (4) Library 13 is the method and content of each Wei value; the power supply 14 can be a general battery power supply or AC power supply The output device 15 is a display device. Comprising: computer means of firefly wheel into the sensing device 16 may be a keyboard, or a touch button or tents, round-electrode 17 was connected to the sensing of a subject's limb.忒Phase angle 6 is estimated to be the platform 2 为 is the aforementioned phase angle database η frame constitutor 》 玄 phase angle evaluation platform 2 〇 is a phase angle 0 and the age of the subject Age and bioimpedance phase angle estimation BMI The platform of the relationship form. The process of the measuring method includes: inputting the shell material 31. The subject inputs the data of the subject on the input device 16 of the measuring device 1 (), including: the height and weight of the subject, Age, gender, and physical status; ^Selection standard module 32: By computer _, in the above-mentioned data, the phase angle evaluation platform has a close-to-tester pole-mode mountain angle database 12Select the most soap system 'and take the standard value 21, including: phase angle sample, · ^谷谷 'quasi- and resistance value standard value; bio-impedance phase angle estimation standard value is the ratio of 4 33: The measuring device 1()>& is placed in the body of the human body of the subject, and the input sensor 17 of the body of the subject is measured at the end of the limb, and the electric quantity can be set separately. The angle is estimated to form a pair of angles and a bioimpedance phase I value of 22, the control value 22 includes: an electrical impedance value, a ^/9664 object impedance phase secret, etc. The electrode pair structure 'through the single-chip central processing of the measuring device 1 Π: Π cooperate with the phase angle database 12 and construction Database 13 is formed by a phase angle = 2〇 internet 'so that each of the control values may be estimated 22 billion level converter 20 via the phase angle of the formed assessment of the value of each of the reference value 23. Alignment 34: the phase angle evaluation platform 2 再 re-aligns the standard value 21, the comparison value 22, and the reference value 23; integration 35: compares the values in the previous steps, and uses homogeneity Each value forms a search for the standard deviation of each of the 'standards' data, and the recommended content of the standard deviation of the mouth is taken out. The values of the above-mentioned factors and the statistical analysis are built. The acquired Wei content is listed on the same-form; the physiology 2 is taken to use 'the difference between the value and the suggestion to know its physiological age status. The phase (4) database 12 structure is effectively established. The phase angle database 12 module establishment process 40 includes: 乂 and phase s ^ 又 财 $ measured impedance value, bioimpedance phase angle estimation Each of the valleys, a large number of different subjects are measured; the construction of the phase angle evaluation platform 42: state, gender and other conditions to construct different ages, body age and bioimpedance phase angle estimation, etc.: : and 'and form a phase angle, and other conditions for statistical analysis to form a phase 1371664 • . Day correction replacement page angle evaluation platform 20 and phase angle database 12; -~ - form database 43: standard module department under different conditions The records are statistically analyzed by means of cumulative measurement and standardized to form the standard values of each module and recorded. The modular analysis of the phase angle evaluation platform 20 is based on statistical analysis. If the national race is targeted, the relationship between the phase angle Θ and the age of the subject and the bioimpedance phase angle estimation BMI The formula is as follows: male : (Θ) = Clmale + C2male x Age + C3male x BMI Female : (^) = ClFemale + C2Female x Age + C3Femalex BMI where C1-C6 are the coefficients obtained by statistical analysis, so the aforementioned comparison value & Two or two can be substituted into the relationship between the standard modules to obtain different reference values 23, which can be known by the difference between the comparison value 22 and the reference value 23 and the standard deviation between the comparison value ^ and the standard value 21. What is the difference between the actual situation of the subject and the standard value or the reference value? The subject can obtain the difference values in each relationship of the phase angle evaluation platform 20, and close to the suggestion database 13 to select the corresponding content, and the output can be viewed from the form. Among them, by the difference between the control value 22 and the standard value 21, the physical condition of the subject is different from the scale of the towel. H can be compared with the reference value 23 to know the direction in which the values may be mutated. By. In summary, the invention discloses a device and method for measuring the bioimpedance phase angle of the human body. 13 1379664 The correction of the replacement page to measure the physiological age indicator in August 101, the special design has been "having industrial availability" Undoubtedly, in addition to this, the technical features revealed in the creation of this case have not been seen in publications before the application, nor have they been used publicly, and in addition to the fact that the effects are enhanced as described above, the present invention The "novelty" and "progressiveness" are in line with the provisions of the Patent Law, and the application for the creation of a patent is filed according to law, and the application is reviewed and the patent is granted as soon as possible. [Simple description of the diagram] Figure 1 is a schematic diagram of traditional bioimpedance analysis. Figure 2 is a schematic diagram of a conventional phase angle. Figure 3 is a schematic view of the measuring device of the present invention. Figure 4 is a schematic diagram of the measurement method of the present invention. Figure 5 is a schematic diagram of the process of establishing the phase angle database of the present invention. [Main component symbol description] Measuring device 10 Central processing unit 11 Phase angle database 12 Recommended database 13 Power supply 14 Output device 15 Input device 16 Input sensor 17 Phase angle evaluation platform 20 Standard value 21 Control value 22 Reference value 23 Measurement Method 30 Input Data 31 Selection Comparison Standard Module 32 Comparison 34 Measurement of the Testee's Alignment Value 33 1379664 Integration 35 August 2011 e-Revision Replacement Page Generation Form 36 Module Creation Process 40 • Measurement 41 Constructing a phase angle evaluation platform 42 forming a database 43 15

Claims (1)

/y〇〇4 七、申請專利範圍: - 1、一種人體量測生物阻抗相位角估測生理年齡指標之 I置’其中’該量測I置係包括: 一中央處理1 ’該中央處理ϋ連接有-相位角資料庫以 及一建議資料庫’以形成—相位角評估平台之主體,而該中 央處理器另連接-電源、—輸出裝置、至少—輸人I置以及 複數個輸入感測器; -玄相位角„平估平台係為一相位角0與受測者之年齡八狀 以及身體質量指數BMI的關係平台; 該相位角資料庫係各標準模組之資料内容,包括:年 齡、性別、體能狀況、人種、國別、電阻值、生物阻抗相位 . 角估測與相位角; 、 該建4¼料庫則為各項數值欠缺或超出時之因應方法 與内容者; 該輸入感測器則為接於受測者肢體上之電極對者。 2 .如申請專利範圍第1項所述的人體量測生物阻抗相 位角蚀測生理年齡指標之裝置,其中,該中央處理器為一電 腦之處理器,相位角評估平台係與人體電抗值無關;該電源 則為〆電池電源或交流電電源者;該輸出裳置係為顯示裝 置’係包括:電腦之螢幕;輸入裝置則為鍵盤或按鍵或觸控 螢幕者。 1379664 3 •一種人體量測生物阻抗相位角估測&年^ 方法,其中,該量測方法之流程係包括: 輸入資料:受測者於—量測裝置的輸人裝置上輸入本身 之資料包括:受測者的身高、體重、年齡、性職體能狀況 等資料; 選擇比對標準模組:藉由電腦判斷,以前述之受測者資 料中’於-相位角評估平台中之相位角資料庫選取最相近於 受測者之標準模組’並取出該標準模組中之各項標準值,包 括:相位角標準值、生物阻抗相位角估測標準值以及電阻值 標準值; 里測又射之比對數值:藉由針對於受測者人體之肢體 /量測裝置之各輸人感測器,該輪人感測器其可各別 設於受測者肢體之末端,量其修抗值、相㈣以及生物阻 抗相位角估測,以形成對照值,該對照值係包括:電阻抗值、 相位角以及生物阻抗相位角估測等指數之數值;而輸入感測 盗係為-電崎結構,透過該量職置之片中錢理器配合 才目位角資料庫與建議資料庫形成i位㈣估平台,以使前 =各對照值可經由該相位角評估平台之轉換形成前述各 數值之參考值; 比fi :於目㈣評估平台針對各標準值對照值以及 參考值進再行比對者; 整合:將前步驟中之值比對後,進入建議資料庫中進行 =;斗之拽尋,使符合各項建議内容得以取出, 101年8月?^日修正替換頁 得產生表單:將前述之各項數值以及經由建議資料庫中取 侍之建議内容共同列於同一表單上者; 文測者予以取用,即可由該數值上之差異以及建議得知 /、生理年齡狀態。 4 一種人體量測生物阻抗相位角估測生理年齡指標之 方法,其中,該相位角資料庫之模組建立流程係包括: 里測·針對受測者量測阻抗值、生物阻抗相位角估測以 及相位料數值,運用生物阻抗法進行量測,分別得到前述 各數值内谷,大量且不同的受測者進行量測; a建構相位角評估平台:針對各受測者之年齡、身體狀 態、性別等條件建構出不同之標準模組,並形成以相位角、 年齡與生物阻抗相位角估測等條件予以統計分析 角評估平台以及相位角資料庫; 形成資料庫:於不同條件之標準模組部份,以累積受測 者之方式予以統計分析並統—標準化形成各模組之標準值 而予以記錄者; 該相位角評估平台之模組化分析,係以統計分析為之, 係為-相位角Θ與受測者之年齡Age以及生物阻抗相位角估 測BMI的關係如下: male : (0) =Clmale+C2male x Age+C3male X BMI 1379664 101年8月q日修正替換頁 Female : (0) = ClFemale+C2Female X Age +C3Femalex BMI。 19/y〇〇4 VII. Patent application scope: - 1. A human body measurement bioimpedance phase angle estimation physiological age indicator I set 'where' the measurement I system includes: a central processing 1 'the central processing ϋ Connected with a - phase angle database and a suggested database 'to form a body of the phase angle evaluation platform, and the central processor is further connected - power supply, - output device, at least - input I and a plurality of input sensors - The mysterious phase angle „ flat evaluation platform is a platform for the relationship between the phase angle 0 and the age of the subject and the body mass index BMI; the phase angle database is the data content of each standard module, including: age, Gender, physical condition, race, country, resistance value, bioimpedance phase. Angle estimation and phase angle; The construction of the 41⁄4 library is the method and content for the lack or excess of various values; The measuring device is an electrode pair connected to the limb of the subject. 2. The device for measuring the physiological impedance of the bioimpedance phase angle eclipse according to the first aspect of the patent application, wherein the central portion The device is a computer processor, and the phase angle evaluation platform is independent of the human body reactance value; the power source is a battery power source or an alternating current power source; the output is a display device that includes: a computer screen; the input device is For keyboard or button or touch screen. 1379664 3 • A human body measurement bioimpedance phase angle estimation & year ^ method, wherein the measurement method includes: Input data: the subject is measured The information input on the device's input device includes: the height, weight, age, and physical fitness status of the subject; the selection of the standard module: by computer judgment, in the above-mentioned subject data The phase angle database in the phase angle evaluation platform selects the standard module closest to the subject' and extracts the standard values in the standard module, including: phase angle standard value, bioimpedance phase angle estimation The standard value and the standard value of the resistance value; the ratio of the measured value to the measured value: the human sensor is sensed by the input sensor for the limb/measuring device of the human body of the subject They can be placed at the end of the limb of the subject, and the value of the repair, phase (4) and bioimpedance phase angle are estimated to form a control value, which includes: electrical impedance value, phase angle, and bioimpedance phase. The value of the index is estimated by the angle; and the input sensing thief is the structure of the electric wave, and the i-bit (four) estimation platform is formed by the money processor and the recommended database in the film of the volume. The former = each control value can be converted by the phase angle evaluation platform to form a reference value of each of the foregoing values; the ratio fi: the target (4) evaluation platform for each standard value comparison value and the reference value to be re-aligned; integration: After the comparison of the values in the previous steps, enter the recommended database for the test; to find out that the contents of the recommendations are taken out, and the correction of the replacement page in August, 101? The values and the suggestions submitted through the suggestion database are listed on the same form. If the tester takes it, the difference between the value and the suggestion can be known as / physiological age status. 4 A method for estimating a physiological age indicator by a human body measuring a phase angle of a bioimpedance, wherein the module establishment process of the phase angle database comprises: a measurement method, a measurement impedance value for the subject, and a bioimpedance phase angle estimation And the value of the phase material is measured by the bioimpedance method, and the above-mentioned numerical values are obtained, and a large number of different subjects are measured; a constructing phase angle evaluation platform: for each subject's age, body state, Gender and other conditions construct different standard modules, and form a statistical analysis angle evaluation platform and phase angle database based on phase angle, age and bioimpedance phase angle estimation; form a database: standard modules under different conditions In part, statistical analysis is carried out in the form of cumulative test subjects, and the standard values of each module are standardized and recorded. The modular analysis of the phase angle evaluation platform is based on statistical analysis. The relationship between the phase angle Θ and the age of the subject and the bioimpedance phase angle estimation BMI is as follows: male : (0) = Clmale + C2male x Age + C3male XB MI 1379664 Correction replacement page for August 101, 2011 Female: (0) = ClFemale+C2Female X Age +C3Femalex BMI. 19
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