TWI379000B - - Google Patents

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Publication number
TWI379000B
TWI379000B TW98132918A TW98132918A TWI379000B TW I379000 B TWI379000 B TW I379000B TW 98132918 A TW98132918 A TW 98132918A TW 98132918 A TW98132918 A TW 98132918A TW I379000 B TWI379000 B TW I379000B
Authority
TW
Taiwan
Prior art keywords
pressure
culture
chamber
mechanical force
patent application
Prior art date
Application number
TW98132918A
Other languages
English (en)
Chinese (zh)
Other versions
TW201111501A (en
Original Assignee
Univ Chang Gung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Chang Gung filed Critical Univ Chang Gung
Priority to TW98132918A priority Critical patent/TW201111501A/zh
Priority to US12/651,905 priority patent/US8980624B2/en
Publication of TW201111501A publication Critical patent/TW201111501A/zh
Application granted granted Critical
Publication of TWI379000B publication Critical patent/TWI379000B/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/44—Multiple separable units; Modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/14—Pressurized fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Clinical Laboratory Science (AREA)
  • Mechanical Engineering (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
TW98132918A 2009-09-29 2009-09-29 High throughput cell culture system capable of providing mechanical force pressing stimulation TW201111501A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
TW98132918A TW201111501A (en) 2009-09-29 2009-09-29 High throughput cell culture system capable of providing mechanical force pressing stimulation
US12/651,905 US8980624B2 (en) 2009-09-29 2010-01-04 Apparatus for high-throughput cell culture with mechanical compression stimulation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TW98132918A TW201111501A (en) 2009-09-29 2009-09-29 High throughput cell culture system capable of providing mechanical force pressing stimulation

Publications (2)

Publication Number Publication Date
TW201111501A TW201111501A (en) 2011-04-01
TWI379000B true TWI379000B (enExample) 2012-12-11

Family

ID=43780825

Family Applications (1)

Application Number Title Priority Date Filing Date
TW98132918A TW201111501A (en) 2009-09-29 2009-09-29 High throughput cell culture system capable of providing mechanical force pressing stimulation

Country Status (2)

Country Link
US (1) US8980624B2 (enExample)
TW (1) TW201111501A (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10066198B2 (en) * 2013-09-05 2018-09-04 Universität Bern Device for in-vitro modelling in-vivo tissues of organs
CN108026214B (zh) 2015-05-30 2021-03-02 基因组股份公司 乙烯基异构酶-脱水酶、烯醇脱水酶、芳樟醇脱水酶和/或巴豆醇脱水酶及其制备和使用
CN107603878B (zh) * 2017-09-05 2025-08-08 广东省第二人民医院 一种体外模拟按压环境下的细胞培养装置
EP3707235B1 (en) 2017-11-06 2022-07-06 Fondazione Istituto Firc Di Oncologia Molecolare (IFOM) Cell compression device
CN108728360B (zh) * 2018-06-09 2024-04-09 上海天引生物科技有限公司 一种细胞共培养的装置及其方法
TWI732357B (zh) 2018-12-27 2021-07-01 財團法人工業技術研究院 細胞培養裝置及方法
JP2020110117A (ja) * 2019-01-15 2020-07-27 株式会社島津製作所 細胞処理容器及び細胞処理装置
CN112877212A (zh) * 2021-03-08 2021-06-01 大连医科大学附属第一医院 一种基于微流控芯片的仿生体内关节软骨微环境的结构
CN120173741B (zh) * 2025-05-21 2025-08-12 江苏艾玮得生物科技有限公司 体外模型培养芯片、装置及动态培养系统

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5153136A (en) * 1988-07-22 1992-10-06 Vandenburgh Herman H Apparatus for growing tissue specimens in vitro
US6048723A (en) * 1997-12-02 2000-04-11 Flexcell International Corporation Flexible bottom culture plate for applying mechanical load to cell cultures
FR2803852B1 (fr) * 2000-01-17 2004-11-05 Farzin Sarem Dispositif de culture cellulaire et tissulaire a circulation de fluide de culture controlee
US6653124B1 (en) * 2000-11-10 2003-11-25 Cytoplex Biosciences Inc. Array-based microenvironment for cell culturing, cell monitoring and drug-target validation
WO2004094586A2 (en) * 2003-04-18 2004-11-04 Carnegie Mellon University Three-dimentional, flexible cell growth substrate and related methods
US8557582B2 (en) * 2007-09-28 2013-10-15 Christopher MORAES System, apparatus and method for applying mechanical force to a material

Also Published As

Publication number Publication date
TW201111501A (en) 2011-04-01
US20110076758A1 (en) 2011-03-31
US8980624B2 (en) 2015-03-17

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MM4A Annulment or lapse of patent due to non-payment of fees