TWI358540B - A novel method for chromatographic finger printing - Google Patents

Description

V. INSTRUCTIONS (1) 5 ~ 1 Field of the Invention Technical scope: Standardization of treatment. A new method for characterization can be used for chemistry and organic and organometallic molecules. The chromatographic characterization of the present invention is related to matter, animal or any other; m-visible radiation absorption characteristics in the plant. The present invention facilitates the production of a bar code for early u- or compound drug abilities. The present invention also relates to all of the components of the characterization information regarding the rate: commercial use of the levied database, with the development and use of enterprise resources (erp, 11 erprise Resource P 1 ann i ng) Information about customer relationship management ('Customer Relationship Management') computer network geese vending machine. ~ Using a layer such as the spectrum of the experimental material (the invention utilizes a contour of an herbal and formula and 3-D color layer Contour and 3-D chromatograms), developed from a standard (chemical and instrumental) environment, a new method is proposed As the drug analysis feature. Further, the present invention relates to a color chromatogram of a computer using a method of using a computer. This new method is very useful for the reliable identification of the chemical chemistry of a single drug and formulation. Thousands >

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5-2 Background of the Invention History of Traditional Herbs in the World After many years of evolution, the ancients began to think about themselves and tried to understand that the self began to live under shelter, burrowing and living in groups. This thought process encourages people to understand nature and its internal activities including biology. Start using ...'' plants and animals to provide their daily needs, in ancient times. In the two plants and animal materials as their dietary and health needs are also too long to 'discover the nature of different ingredients in the world' such as various organisms /, plants, | J He Gezhi, the soul of And medicinal properties. This phenomenon occurs from the stone device + this + , ^

a ^ The guardian has a written record to begin with. Ancient people continued to explore 'standardization. Naturally available materials are used in day-to-day life. The process takes place in many parts of the globe, parallel to different parts of the world, and there is more development in places where more civilizations are developed by intellectuals. Therefore, the history of the drug has a direct relationship with the history of the culture. In India, there has been evidence of a well-organized system of drugs in Harappa and M〇hanzadaro (drug history in India)

'Histry of Medicine in India, Dr. Pr i y a Vrit Sharma, Indian National Science Academy, New D e 1 h i ). In the Indus culture, a system of drugs has become popular, using the 'animal and mineral sources of medicine' for vegetables. The Ossar Seak Tower (0sadhisukta) in Rigveda is the earliest

Page 6 1358540 V. INSTRUCTIONS (3) Knowledge documents on plants and herbs. The drug in India is due to the traditional knowledge of Atharveveda, of which Ayurveda is called Upaveda. Defining and narrating a large number of disease complications in the papers of Charaka and Suslut (8113 1'1^3), Sam Haitas // (Ding 116831111^7 35). The treatment is also prescribed in a systematic manner and on a reasonable basis. On the other hand, it can be understood that this biological phenomenon cannot be universally explained by mechanized tools when each individual in its basic composition changes. That is, when specifying a diet or medicine for a patient, it must be remembered. Prakruthi. The concept of duality, such as Prakriti-Purusha, Yin-Yang, normal-abnormality can be seen in most philosophies. Disease is a manifestation of fluid imbalance and must be treated extensively on a physical and psychological basis. Therefore, health is the balance between the psychological and spiritual levels of the body. Therefore, the three-dimensional definition of health proposed by Susrtuta is an ideal definition that has been accepted by the modern World Health Organization (WHO) and reflected in its definition. After discussion in the ancient literature, it was found that the drug can be standardized by the physical-chemical properties of its materials. Its color, texture, aroma and taste are used as a basis for judging the efficacy of any drug. Even the shape of the drug is used

Page 7 1358540 V. Description of the invention (4) to understand the drug's medicinal properties. A summary of the different philosophies and various elements used in therapy is presented in Tables 1-6, which are described later. Figure 1 specifically provides a detailed information on the individual philosophy and concepts in India. Awkal, the traditional Chinese medicine (HM's "Drug in China" and by Daniel Reid, Simon and Scots The 'Handbook of Chinese Herbal Medicine'; Medicine in China by Η. M. Sais and A hand book of Chinese Healing Herbs by Daniel Reid, Simon & Schuster) and general philosophy. The efficacy of a drug is ultimately based on the chemical composition used in the drug and the chemical nature of the component will bring about the necessary changes in the chemical composition of the organism. Many scholars of Ajal Verda (an Indian drug system) have defined and classified drugs in terms of color and efficacy. A short summary is presented in Table 7 and appears in a later narrative. Therefore, the physical and chemical properties of the material and human are included in consideration of its properties and used in therapy to achieve the desired therapeutic effect. Table 8-9, which appears in the later section, provides information on how its physical properties (color) and chemical properties (taste) are used to understand the efficacy of the drug and its effects on human physiology. Some of the work of the present invention also uses the same methodology, but is carried out with the instrument. In general, the constituent molecules present in medicines and foods can be broadly classified into three categories, such as polar, medium-polar and non-polar molecules. The total polarity of the molecule is based on the portion of the molecule that is attached to the total electrophilicity and nucleophilicity of the molecule in a conjugated form with the degree of unsaturation of the molecule. Living human body, animal body and plants

Page 8 1358540 V. INSTRUCTIONS (5) The body will also contain molecules of the same type in which molecules of different polarities will perform different functions. The disease can be treated with a drug of the same polarity as the chemical component that caused the disease. In other words, a messy drug can treat the same mess, as Dr. Hanemann said. The definition of herbal medicine by the World Health Organization, the World Health Organization has defined herbal medicine as a 'completed, labeled pharmaceutical product that includes an effective ingredient gas or a subterranean part of a plant, or other plant material or whatever It is in the unprocessed state or as a component of plant blending. Plant materials include their juices, gums, fatty oils, essential oils, and any other natural substances. Herbs may include adjuvants (e X c i p i e n t s ) attached to the active ingredient. Drugs containing plant material that are combined with chemically defined active substances, including chemically defined substances isolated from plants, are not considered herbal medicines. Exceptionally, herbs in some countries also contain, naturally, non-plant derived natural organic or inorganic active ingredients. 〃 Therefore, the purpose of these guidelines is to define the basic norms for the quality and safety of herbs, so that government authorities, scientific institutions, and manufacturers can guarantee a certificate. / Power of Attorney / Evaluation of relevant files in the care of such products. Well, as in the general rule of the evaluation, traditional experience refers to the long-term use of these products and the medicinal, historical and ethnographic backgrounds that must be considered. The definition of long-term use may vary from country to country, but it must be at least several centuries. Therefore, the evaluation needs to consider a description in a medicinal/pharmaceutical literature or similar source, or a

1358540 V. INSTRUCTIONS (6) There is no clear definition of knowledge voucher in the application of herbs. Authorization for the sale of similar products must also be considered. According to the report > The evaluation of this quality is carried out with the following variables? · The World Health Organization's guidelines provide an assessment of the effectiveness of the finished product, its activity, and the product that must support its signs and combinations. Many herbal medicines are made up of a combination of several active ingredients, and although the experience of traditional medicine is usually based on a combination of products, there must be different evaluations between new and old combinations. The same need for an evaluation of the old and new combination products ί will result in an inappropriate evaluation of a traditional medicine. In the case of traditionally used combination products, the credentials of the traditional use (such as the classic version of Ajalta, traditional Chinese medicine, Unani and Sidha) and experience can be used as its efficacy. prove. An explanation of the new combination of known substances, including the effective dose range and suitability, must be attached to each of the traditional components of a single component. Each active ingredient contributes to the utility of the drug. Clinical research is necessary to define the utility of a new ingredient and its positive impact on the overall portfolio. It is also important to note in this report that the manufacturing process and molecular formula, including the amount of the adjuvant, must be described in detail. A completed product manual must be confirmed. A method of confirmation and, if possible, the quantification of the plant material in the finished product should also be confirmed. If it is impossible to confirm its live

Page 10 1358540 V. INSTRUCTIONS (7) The principle of sexuality must be sufficient to identify a distinctive substance or mixture (for example, ''chromatographic characterization') to ensure the quality of the product. The finished product is subject to the general requirements for special dosage forms. For imported finished products, a complete status confirmation in the exporting country must be provided. The WHO certification program must be applied to the quality of pharmaceutical products entering international trade. Put more assessments of stability, safety and use into the above-mentioned World Health Organization report. The effective control of the quality of the herbs entering international trade also requires close liaison between national agencies to maintain a standard review of all production directions and use of herbs. Similarly, an evaluable study that directs or initiates the utility, toxicity, safety, acceptability, cost, and associated value is compared to the currently used drugs. Therefore, as mentioned above, there is a need for a reliable method of quality control in this work. A match is required, all methods that explicitly mention the above objectives. The recommended analytical method will provide answers to almost all of the above needs. Existing Standardization Methods: Prior to explaining the standardized methods of the present invention, existing standardization methods (chemical and therapeutic) and chromatographic characterization methods are described below. Existing technology in the standardization of chemistry:

Page 11 1358540 V. Description of invention (8) i) Traditionally: The great sage Charaka explained in his Charaka Samhita that 'the understanding of the whole picture will not come from one. Fragment of knowledge 〃 (Sherokka. Sam Haita V 1. 4. 5). This makes it clear to us that the standardization and efficacy of any drug will be in vain if all of its ingredients are not taken into account. The approximate quality and quantity of an herbal medicine will vary depending on many factors, such as geological, ecological factors, time of collection, location of collection, age of collection, and weather during collection. Traditional herbalists are accustomed to selecting a drug based on sensory methods, and at that time, using the color, texture, breath and taste to evaluate the chemistry and treatment of the drug. These methods include intrinsic knowledge and therapeutic effects between or within the drug and body composition to cure the disease. This knowledge varies from individual to individual and depends on individual skills and abilities. In fact, this method is difficult to justify any interpretative agency. Therefore, modern science uses instruments to make various assumptions to eliminate individual factors and promote the reproducibility of data and data. i i ) Modern: The therapeutic properties of any food or drug will depend on its chemical and physical state. Thus, using its physical-chemical properties to understand the chemical formation

Page 12 1358540 V. Inventive Note (9) . A copy will help to understand the efficacy of the drug. The physical-chemical nature of the drug plays an important role in the therapeutic activity of the drug. The properties of these molecules can be studied with two variables, polarity and conjugate properties. Polarity is the result of electrochemical properties because of the different properties of the electrons (nuclear, nuc 1 e 〇phi 1 ic) and accepting electrons (electrophilic, e 1 ectrophi 1 ic ) along the molecule An unsaturated double bond or a bond is attached to the molecule. This phenomenon will affect the rate of activity or reactivity of the molecule in a chemical or biochemical reaction. A full assessment of the total polarity of the molecule will provide a single molecule or group of molecules for chemical and therapeutic efficacy. Therefore, any standardization used to evaluate these characteristics will help to understand its activity. Like the polarity, it is mainly related to the electrochemical properties of the molecule, and the physical structure of the molecule also plays a very important role in the activity of the molecule. The more active sites are attached to the molecule, the more active the molecule will be. The more conjugated (double-bonded or bonded) the molecule, the more chemically and therapeutically the molecule will be. The second variable affecting the activity of the molecule is the arrangement of atoms in the same molecule, which will vary from structure to structure. According to this factor, the isomerized (geometric and optical) molecules play an important role in their biological activities. The nature of this stereoselection allows the molecule to be high in a living organism that undergoes a large number of biochemical reactions simultaneously without interfering with or interfering with each other.

Page 13 1358540 V. INSTRUCTIONS (ίο) Degree selectivity. Therefore, the chemistry of optically active drugs has become very important. In other words, no key (optical molecule) can open a different lock (receptor). Plants typically prepare a combinatorial library of molecules that have the same basic parent structure and differ in the attached functional groups. For example, yellow δ ( (flavones), errones and flavonoids of chaconcones will behave like a compound when they are found in nature and a single plant has the form of these molecules. Drug). Usually with unsaturation and many conjugated molecules will absorb electromagnetic radiation in the ultraviolet-visible region (200-800 nm). When the molecule interacts with radiation, the molecule will be based on its chemical conjugate and structural properties. Absorbs a special wavelength (maximum absorption). This is called the characteristic wavelength (characteristic wave 1 enth). A molecule may have more than one maximum absorption depending on the nature of its structure and functional groups. When a molecule absorbs a particular color from white light, the molecule will exhibit other synthetic colors that are not absorbed. Therefore, the material will exhibit different colors depending on its chemical composition from different colors of white light and show that the color is caused by different functional groups attached to the molecule (the table 10 0 appearing in the later description has the same explanation of). The same principle is used for the measurement of chemical and physical properties on spectrophotometry.

Page 14 1358540 V. INSTRUCTIONS (10) How modern science completes standardization. According to reports (WWW//Shilajit, Fulvic acid etc, html), a drug that is very important in the Indian medicinal system, reported that many components are present with Fulvicacid, and For the principle of effectiveness. When collecting bituminous chemicals from many years after storage on land, it can be seen that the longer they are stored on land, the more effective they will be. However, changes in the 'global' geology may not produce the same molecules in all samples from around the world. Another chemical factor affecting these drugs is the process of their purification, which also needs to be standardized. According to the report (WWW//Herbology.html), most of the standardization for key components has been completed. This standardization is empirically and scientifically proven to be very helpful for human systems. So generally, a certain standardization beyond all existing molecules that have been found to be active. However, the addition of other ingredients in the drug makes the overall profile of the drug mandatory for its efficacy considerations. According to the report (WWW//Tribulus Terrestrius puncture vine, html), the alcohol extract of the fruit of the Tribulus Terrestrius showed anti-urethral stones (a n t i u r ο 1 i t h i a t i c ). In addition to this, the extract also showed a significant diuretic activity. The biochemical Harman was reported to have come from the herb and the Harmine is from its seeds. The plant contains saponins,

Page 16 1358540 V. INSTRUCTIONS (13) Steroidal saponin can be produced after hydrolysis. Many molecules in natural flavonoids have been reported to find saponin in their principle of activity. This analysis provides heavy metal analysis and total saponin content (20% w/w). According to the report (WWW// Chra k_ com.—Quality control page-html), human life is a collaboration between psychophysiology and the components of the soul, which is related to the Indian philosophy mentioned in Ajul, Pita (Pi Tta), Kapha, and Vata are considered to be the basis of human health as a whole. The more detailed part of the standardization is placed in the narrative of the standardization of treatment in traditional methods. According to the report (WWW//Standardized Herbal Extracts\ A Herbalists Perspective^, Dr. M i chea 1 T i erra L. Ac. 0. M. D html), due to the European Guaranteed Potency Law Standardization becomes mandatory. The standardized meaning of herbs is defined as the quantification of an active ingredient or labeled extract if the activity of the drug is primarily attributed to these ingredients. According to the explanation (Frank R Stermitz et al, PAINS/Febl 5, 200/Vol 97, No 4, ppl 433-143?), in the plant Berber is Aristata, the antibacterial property of the extract is due to In the presence of 5-Hydroxy Hydnocarpin, this berberine plays a role in fighting microbes. 'Nothing is not enough. Therefore, when dealing with an herb that has more than one active ingredient, the addition of all its ingredients must be tested.

Page 17 1358540 V. Description of invention (14). The World Health Organization clearly mentions the drug in its local publication (Dr. Runzit Roy. Jodrill, Herbs for Human Health; Dr. Ranjit Roy Choudary, Hrebal Medicine for Human Health, Searo no 20) The best practice on what is standardization and how Member States should implement it. The acidic and anatory role can be known from the different pH values of the extract used in the extraction of the drug. This helps to understand the release of the drug in the intestine because the consumption of the drug will vary depending on the pH of the intestines. In understanding the efficacy of a drug, carefully study its role in acidity and alkalinity. The acidity and alkalinity of organic and inorganic molecules have been thoroughly studied to understand their properties as shown in Table 11, which appears in later description. It shows a healthy and acidic character in terms of acidity and alkalinity (, the health of the hands is written by Divandra Fola, the Navalite publication (India) is limited; Health in Hands by Devendra Vora, Navaneet publications (Indea) Ltd). According to the report (WWW//Chewing. Html), it was found in a study that people with acidic constitutions absorbed more pollutants than those who had established appropriate blood alkaline islands. Acid testing (p Η value) balance is important for normal cellular function. A more detailed section will be discussed in the article. Therefore, the discussion of acidic or basic (organic or inorganic), in terms of 'polarity', will provide information on the efficacy of the drug. Therefore, the current method is competent for this work and will be used in large quantities to understand the efficacy of the drug. Use the recommended party

Page 18 1358540 V. The invention (15) method can determine the acidity and alkalinity used in the standardization of the treatment of drugs. The above references will explain the common and reported methods of standardization in which the individual components are separated onto a prepared scale and compared qualitatively and quantitatively to the same compound present in the study sample. One of the newspapers, J. et al., US Patent 6, Palmetto, Khwaja, Out, a different part of the Balmian sawtooth palm, also discussed the total fatty acid in the test containing half of the effective concentration in the linoleic acid ethyl laurate B. (1 auric out. Each part of it is calculated for males. The analysis has been calculated for its molecular weight and individual lipid activity. The linoleic acid and lauric acid beta (pharmaceutical grade of Balmer sawtooth palm , Kui 039, 950; Pharmaceutical grade Saw et al US Patent 6, 039, 950) The alcohol extract of the middle finger (Saw Palmetto) was used to study its biological activity in the inhibition of male hormone receptor binding (1C 50). Detection of the content of the substance and individual parts. (linoleic acid ethyl ester) and part of the monthly acid ethyl ester) have been identified to inhibit the binding of hormonal receptors. Activity can be counted as the total biological activity of the comparison of the sample. The fatty acid content has been identified and included in the extract. The total biological activity is calculated as an overall percentage of the activity of the ester moiety. In the standardization of this traditional medicine, its overall profile must be included in the consideration of the efficacy of the herb. Therefore, in today’s method of using computer instruments,

Page 19 1358540 V. INSTRUCTIONS (16) All ingredients ^ are considered to be the top of the traditional concept world with biomass. The characteristics of the drug are proposed to be a visible tool and proof of the effectiveness of many special traditional drugs. Prior to discussing the method of the invention, the existing analytical methods are described below. Existing analytical methods for chemical standardization. The improvement and use of modern analytical methods and instruments has clearly led to the advantages of drug quality control. Improvements in analysis have led to many of the above-mentioned herbs having more accurate results and helping to prepare standardized extracts. Any one can provide a reliable identification as the characteristics of the plant. Although there are many medicinal plants using microscopic and physical methods, the traditional methods of Zhongding, such as sensory, but in terms of their chemical profile, there is no flaw.

Therefore, the chromatographic characterization method is more useful in the quality control of medicinal plants to replace other sensory and microscopic studies. Finally, a large number of chemical ingredients involved in the efficacy of the drug, along with other properties of the herb; S Hai chemical composition analysis data must provide reliable efficacy of the drug. The characteristics of a body seem to provide its own characteristics. Until such as 5" Thin Layer Chromatography (TLC) to the effect of this thin layer analysis (High Performance Thin

Layer Chr*〇raat〇graphy, HPTLC), and high pressure (performance) liquid chromatography (High pressure (Performance) Liquid

Page 20 Γ/Ι358540 V. Description of invention (17) --

Chromatography) is a method generally used for the analysis of organic or organometallic compounds and features. However, these methods have advantages and disadvantages when used in the reliable analysis of a drug. Table 丨2 appears in a later narrative comparing several existing analytical methods and provides a general insight into the advantages and disadvantages of the method. Figure 4 of this specification shows how a color chromatogram developed by the thin-layer analysis method, chromatographic characterization, can be used on the labeling of commercial products. This feature does not provide any information other than the analysis of the ingredients. After reviewing the above table, it was found that the technical chromatographic layer method '' is most suitable for use in mixture analysis, which provides an overview of the mixture after separation and identification by a suitable detector. Among the techniques of several layers of color analysis, the most suitable one is high pressure liquid color.

High pressure Liquid Chromatography (HPLC). Although the analysis of thin color layers has been used to date, advances in the field of high-pressure liquid phase chromatography and separation columns have completely changed the field of analysis of color sounds. Beta knife n Most pharmaceutical analyses are reported in the form of a color chromatogram. The chromatogram contains some of the absorption peaks obtained after the molecules have been extracted from the official data or pharmacopoeia (m 〇 b i 1 e p h a s e ). The p-forming method is performed on a separation column subjected to high-pressure liquid chromatography analysis.

Page 21 1358540 V. INSTRUCTIONS (18) After analysis with any appropriate detector. Usually, the chromatography method uses a reference standard (internal standard method or external standard method) during operation. If a standard reference is missing, the analysis does not make any sense because the absorption peak on the chromatogram does not provide any chemistry about the compound being flushed. Therefore, the qualitative and quantitative confirmation of the composition (spectral or chemical) becomes unclear. In the qualitative and quantitative analysis of medicines/drugs (single or formulation), the main emphasis is on the spectral and chemical properties of the components being flushed after the samples have been analyzed. The completion of the analysis is based on the effect of electromagnetic radiation (referred to as UV-visible radiation) on the analyte and the response of the analyte. In existing chromatographic methods, the analytical report, that is, the chromatogram does not provide any chemical properties such as polarity and UV-visible absorption properties of the component. The chromatogram does not show those 'maximum absorptions 11 that do not absorb at this wavelength or have a different wavelength than the set wavelength (2 2 5 or 2 5 4 nm). Even though the sample is 100% pure, even though it is a known molecule and the analysis is at an acceptable fixed wavelength, it is highly impractical in a drug case containing more than one active molecule. A number of examples at a single wavelength are shown in Figure 5-1, where there are many different wavelengths. None of the single chromatograms provide the complete chemical properties of the ingredients of conventional drugs containing more than one active substance. When these chromatograms are compared to features, the use of the feature can be understood.

Page 22 1358540 V. INSTRUCTIONS (19) Therefore, any chromatogram at a particular wavelength does not provide a complete chemical profile of the material in a single drug and a formulation. Therefore, this chromatogram is part of its report and is unacceptable. Any method of analysis, if it is impossible to present complete information about the analysis, is not scientific. In the analysis of an herb, different kinds of molecules with different spectral properties (maximum absorption) at a fixed single wavelength chromatogram will no longer be meaningful analytical reports or chromatograms. In the use of herbal medicines, the overall drug is used in the standard treatment environment specified in some ancient literature or manuscripts. Therefore, the concept of finding an effective ingredient is considered to be incomplete because the complete profile is the cause of the drug's medicinal properties. Therefore, any analytical method would not be useful without the complete chemical nature of all the components of the drug in the study. State and life, multi-generational years of collection, the collection of points and the steepness of the point. When the time is equal, etc., the situation of the medicine is set in the form of a collection of winds, such as the plot of the season, and the collection of the monosyllabic elements has been mentioned (Frank R. Stelmiltz et al.) (Frank R Stermirtz Et al), the additive effect associated with the main component is also important, since the addition cannot function without the presence of other components in the extract, as explained earlier.

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Standardization of treatment Traditional methods: The nature of great Indian medicine, the composition and body fluids into the interior created between them, the basic concept contains roles. It is said to consist of the human body Saptahatus). There are three. The role of any tantra's pancha combination in the universe will affect its existing philosophers who understand its physics and chemistry: the definition of biology and the understanding of traditional philosophical Tahatus , ,Tridosha) elements (Pan Tong's change and understanding will help its efficacy. The concept of the world society Saints have understood and defined the concept of Indian medicine by clarity. The relationship between it and the nature In human body fluids are composed of seven components (Sarp 5 general disorders (promoting the material nature of the Idira material due to five bhutas). These elements are unhealthy. So 'the nature of these properties' and can be used to understand the development of this The class is suitable for its traditions and the ancient Indian era (pa Samhitlc and pre Susrutic peri〇d in India) in the former St. Haitick and the former Seslutik, the healer 'J with Nadis sasi: Ra; study pulse to promote Yidu Xia (cutting tower, Kafa, and Pita) at the time of diagnosis of the second brother) Γ ϊ The health status of the patient. The special kind of pulse (not the heart) Pulse) 7 to explain the types of diseases the patient (history of medicine in India, Puglia • Special • Dr. Sharma made known book, the Indian National Academy of Sciences; History

Medicine in India by Dr. Priya Vrat Sharma, I n d i a η N a t i 〇 n a 1 S c i e n c e A c a d e m y ).

Page 24 1358540 V. INSTRUCTIONS (21) The type of dosha (s) used to understand the patient at the time of diagnosis and the case where the disease was damaged during the treatment. But this study, Nadi's technology, only approves those who have a high level of personal skills and a large amount of training. Therefore, not every traditional practitioner can implement this technology. In order to overcome this phenomenon, it is necessary to develop and standardize the technique of understanding the physical-chemical properties of drugs and human body fluids. These internal and interrelated relationships that affect the natural properties of health have been studied and standardized so that the pharmacology and pharmacotherapeutic techniques are developed by the therapist. The efficacy of a drug is defined by the use of a substance that produces a (pharmacological) effect in the human body (Kryagnaput, Kriyagunavat) and due to several factors in the collection work (Samafa Akaranan, Samavayikaranam, just as the production of the same piece of cloth is the result of a joint performance of many ingredients. There are two main types of organisms in the world, animals and plants. It has also been said that the world is composed of five important elements, namely, the water and the wind (known as the 'Pancha Titas' in Ajulda). There are two basic properties of these substances, called intense (strong) and light (soft). If we agree with this very criticized logic, we can say that it is the combination of all the changes in the world that are due to the above-mentioned nature.

Page 25 1358540 V. INSTRUCTIONS (22) The strength provides a wide range of properties and changes in materials that exist in nature and are considered by nature. This ingredient will contribute to the consistency referred to in Ajal. The two factors mentioned above appear in the table described later. The Chinese medicine's taste for the human body is as described above. These factors are returned. The claim for this factor is completed as will be considered. Most bioenergy centers are directly or indirectly used. Reported on other philosophical points. In Pancha Bu Tike (promoting the concept of Idusia (Pitta, plays an important role in the human body, Saptadhatus). Ayur's emphasis on disease introduction is mostly in the five traditional ingredients of the traditional medicine world. Into the composition of the body to understand the disease and discomfort of the patient. This kind of 'Prussian', in the traditional Chinese medicine called 'Yin and Yang 6' proposed in China's system how to use classification and definition to classify treatment and disease standard state into Yin and Yang are manifested in sadness and quickness due to the different nature of the drug and the chemical, physiological and social factors of the Chinese medicine and the human body. The factors in the acupuncture treatment technology Both have similarities with Chinese medicine, panchabhautic), after learning, the card is issued, and the pagoda) is made up of seven ingredients in traditional Indian medicine (Sapta de Hatus, who believes in all the philosophy of life and The treatment of diseases. All the methods of Ajul are to promote the soul, the mind and the body are the three parts of life and when these are in the balance and harmony of function, Called good health (Ah, if Geya, Arogya). When they are in imbalance and disharmony, the state is called disease (penalty grief enjoy Asian,

Page 26 1358540 V. Description of invention (23)

Va i shamya ) ° "According to Ajul, we promoted the physical characteristics of various systems under the function of the function. In other words, the harmony of Yiduxia implies a good =, and the disharmony of Yidu Xia will cause disease... Hey, most of the 'waiting: Yiduxia must discuss when choosing the music for the discussion of any disease. Promote Idusia.疋戾病会靖Ϊ: The definition is, 'anything will bring sorrow or misfortune to this person (Pu 2: The thing is disease " can be divided into four:;., ς野根塔瓦哈, agantavaha) 2 The body produces (Sali Ϊ 3. Psychologically produced (Minna, Manasah) and 4. Since Qiu Ba from the god card abhavlkah). For this reason, the traditional concept of the Big 4 is to treat diseases in a way that is combined with others. The gods will be divided into three categories based on the rules of life and the standard. I.curable & (Sadya, ahya) 2. Can be moderated or controllable (Asian and West γ,: Healed (Assaya, Dijon, Plus)) 3. Can not be this body = * Ρ). As mentioned above, the main consideration is that the reason for the occurrence of the card: ηί is via the opposite of the promotion of Iduh, that is, the slashing of the card, and the pita and the blood, either individually or separately. Then a is combined with a reason for the reason. Then β is not caused by the reasons, such as psychological factors, the disease is caused by different methods* test _ a. 丨 '\~ 佚 瘆 瘆 瘆 瘅广Μ Μ 1 to deal with. It is appropriate to consider why any traditional concept is included in the mental factors of the disease. Doshas = 1358540 V. Description of invention (24) The individual nature is explained as follows. Yes, the pagoda or vajud 〇sha deals with endocrine, neuromuscular and neurotransmitter-derived activities that cause vital or total motility, and those that cause gas production can be classified in this category. Pitta dosha is related to digestion and chemistry Rasa kriya is roughly associated with Kapha dosha, which provides stability and bonding and lubrication. Like the first summer, the 'vata' is considered to affect the other two factors. It is considered to be the main cause of all diseases. A detailed description of these body fluids has been placed elsewhere in the main body of this article. The reduction of the pagoda will cause slow activity. Therefore, this kind of drug that can reduce the late purity will be Huatahela. (Vata H ara). This reduction in digestive capacity is called Pita Ducha. A drug that can increase the digestive capacity or activate bile (bi 1 e ) mechanism will be natural Pita Hera. To understand the different traditional medicine worlds, a detailed description of all such factors is placed in various philosophies. Tables 1 and 2 (shown in later narratives) provide an Ayuvedic philosophy in India and its A detailed description of the various components. Therefore, in order to understand the efficacy of a drug or food, it is necessary to understand its physical and chemical properties. In ancient times, people used sensory methods, such as

Page 28 1358540 V. INSTRUCTIONS (25) The taste, breath and color of the material are to be understood. These basic properties can be divided into 1 · taste (Risa), 2. quality (Guna, Guna), 3. effectiveness (Veliya, Veerya), 4. Assimilation and influence brought by this component (Vipa) Card, Vipaka) and 5. Special effects (Pulaberhava, .prabhava, geometric and optical isomers). These three factors, the Doshas, the Dhatus, and the Maias, are mainly used to treat diseases or disorders. If the nature of the drug is consistent with the summer, the summer will be damaged or neutralized, so the disease can be cured. The drug is classified and distinguished according to the pharmacokinetics and genetic rules of Ajurda. The situation of doshi c's advantage varies. In other words, there is a correlation between the Drava Gunas (drug) and Duchas (disorder). The increase or decrease of one or more drugs may be forced to the patient who has the same disease and has a different combination of Duchas or Dusit. Therefore, Ajul's drug therapy is more generalized in terms of personalism based on the summer advantage of the patient and not as much as the drug treatment of modern medicine. The identification of the nature of the summer (Roussa, Guna, Vera, Vipaca and Prabhavar) is the only and reliable drug treatment in Ajal. i i ) Modern methods of treatment standardization:

Page 29 1358540 V. INSTRUCTIONS (26) Existing medical treatments do not take into account the above concepts. Phytochemologists are only interested in the separation, purification and structural description of the principle of activity isolated from plants and studied by pharmacologists for biological activity. The pharmacologist then scans the pharmacological activity of the molecule, establishes its role, and generally evaluates its efficacy against existing standards and drugs that have been used in modern medicine. This concept will not help the practitioner of traditional medicine to completely change the full properties of the drug and its efficacy because of the separation of this principle of activity. Substituting the solvent extraction fraction, the principle of activity, etc., from individual plants, using a solvent suitable for human cells and human cell membranes to analyze the total extract from a drug will be evaluated in the pharmacology of these drugs. It is very useful in terms of activity. In the modern clinical trials led by treatment standardization, three phases have been completed (fourth in the case of international utility), involving a large number of people. The information related to a new drug is submitted to the Drug Controller. The usual components are: 1. Chemical structure 2. Pharmacological types 3. Formulation details 4. Animal data includes toxicity study data 5. Clinical pharmacology data includes pharmacokinetics (

Page 30 1358540 V. INSTRUCTIONS (27) Pharmacokinetics) (Pharmaceutical behavior in the human body) 6. Pharmacodynamics (the role of drugs in the body) 7. Special study of the drug's remaining amount in the world And state 8. Data on biobalance studies The first phase of the study focused on the safety assessment of the drug to understand how the drug is absorbed, metabolized and excreted in the human body, and the assessment also envisages estimating the drug's attachment. Function and dose. The second phase of the study focused on testing the efficacy of the drug in a randomized manner. The real medicine will be given to a group of patients and the other group will be a placebo. In the third phase of the study, a number of tests will begin to study the efficacy, benefits, and range of possible adverse effects of the drug. After successfully completing this step, the company will market the drug. In the final phase of II I and I V research, pharmaceutical companies will have many goals. The study will help to understand the efficacy of the new drug compared to existing drugs. The long-term effects and effects of the new drug on the quality of life of a patient will be known. It is also known that the drug therapy has a relative cost-effective relationship with other traditional and new one therapies. But all of the above studies are expensive and time consuming. It won't take into account

Page 31 1358540 V. INSTRUCTIONS (28) Ecological factors, genetic training (eg, proficiency in family and marriage in India), mental, social, and other variables of the patient. This will limit the efficacy of the drug to only a specific ethnic group or human genotype. C. Barcode and Enterprise Resource Planning (ERP) Customer Relationship Management Applications Prior Art Modern methods of manufacturing ownership of any commercial goods are bar codes. Bar codes have been widely used in many ways for all commercial transactions. In order to make the drug recognizable as a monopoly product, a new method of code making is proposed in the present invention. According to the report (Peerne t bar-code store (Java Active X servlet e-business)), there are 1800 characters and 2700 digits (or 9,9 9 , 999) to satisfy a commercially available bar code creation software. Generate a bar code for any item. When a numeric value and/or a numerical representation is supplied to the barcode creation software, the barcode creation software generates a special barcode pattern via which the software ownership is assigned to represent a user. 〃 〃 窗 示 显 显 显 显 显 显 显 显 显 显 显 显 显 = = = = = = = = = = = = = = = = = = = = = = = = = = =0 = = =0 = = = Waiting for the customer's code and the reading of the account can be sourced from the source of the business, what is the product of the sale of a network of equipment, the detector of the ball, or the eye can be over-coded.

Page 32 1358540 V. Description of the invention (29) Read from the application of the management. The number of catalogues has now been bar coded to identify its machine and related products, in particular without any of the characteristics of the products mentioned in the method. 5 - 3 OBJECTS AND SUMMARY: The main object of the present invention is to recommend a new method for the characterization of chromatography, standardization of chemistry and treatment, and from a plant, animal or naturally available or artificially manufactured drug. The material is made of organic and organic metal molecules in bar code. Another object of the present invention is to provide a new method of chromatographic identification for herbs and formulations that eliminates the aforementioned complex disadvantages. Another object of the invention is to provide a complete chemical analysis for studying the composition of a drug. The conjugate nature of the ingredients developed with the new software indicates the efficacy of the traditional concept of the drug. A further object of the present invention is to provide a new method for the chromatographic characterization of herbal medicines which facilitates the rapid identification of actual profiles of compounds having therapeutic ingredients in the drugs used.

Page 33 1358540 V. INSTRUCTIONS (30) A further object of the present invention is to provide a new chromatographic feature for the herb and formula using the contour map of the herbal and formula and the three-dimensional (3-D) chromatogram. Identification method.再 A further object of the present invention is to provide a new chromatographic characterization method for herbal medicines which helps to confirm the presence of impurities in the drug. ""^ A further object of the present invention is to prepare a standard analytical parameter of the ethanol solvent for extraction, the same extraction time, the same dynamic ^ ") and (10) at 5. 5_7.5. T, β Γ The same UV-Vis wavelength range 2〇〇-8〇〇η. Food cold liquid, and the phase of the invention Gg α λα θ and evaluate the polarity and conjugate; The three-dimensional and contour chromatographic drugs are classified on the body fluid as two components: the classification and quantification of the components, and the effect of the (intelligence). The peak of the selected one of the invention provides a code. '疋 is one of the images. The numerator is further developed by the present invention. A database of codes is a further object of the invention for the application of various databases. θ All the details of the sample are shown in the sample. Such as three-dimensional and contour features, barcodes,

Page 34 1358540 V. Description of invention (31) Details of source (factory or country), date of manufacture, date of expiration, reported summer, individual use component, sample test, production serial number, cargo number, M. R · P (maximum retail price) and more. A further object of the present invention is to add separate bar codes to the display window to aid in the processing of the display window as it is used as data and data sources. It is yet another object of the present invention to create a database of display windows for production and affiliated with respective bar codes for use in enterprise resource planning and customer relationship management applications for all commercial transactions of the drug and sample. A further object of the present invention is to create a database of codes and display windows and any information that is particularly desirable for regulatory authorities that control the import and export of drugs in a country. A further object of the present invention is that the ultraviolet-visible spectrum of the compound will provide the conjugated nature of the molecule and the individual concentration of the molecule with the polarity of the molecule. A further object of the invention is that the profile and 3-of spectrum will be chemistry. The basis of the ingredient identification is to define the scope of the invention. A further object of the present invention is for noisy food and drug samples, alternative and contradictory food and drug samples, and commercial food and drug samples.

Page 35 1358540 V. INSTRUCTIONS (32) The sample develops a method of characterization and identifies its purity and inclusions. A further object of the present invention is to develop a method of characterization of organic and organic metal components in various samples to identify chemical components therein as standardization of various purposes and processes for quality control. A further object of the invention is for the treatment of allopathic, Ajul, Homoeo, Siddha, Unani, China, Tibet, Kanpo (Kam ρ 〇, Japan) Drug sample development - a method of characterization as standardization of quality control and chemistry and treatment. A further object of the present invention is to develop a method for characterizing and characterizing the chemical constituents of different naturally occurring or synthetically produced samples. A further object of the present invention is to develop a method for characterization in order to study the different chemical compositions of naturally occurring or synthetically produced samples and to identify and modify them due to geological, ecological, genetic, and phenotypic changes. Factors that cause differences in the chemical composition of the standardization. A further object of the present invention is to develop a method for characterization in order to study and characterize chemical constituents in herbal products of single and compound drug samples as standardization of chemistry and therapy.

Page 36 1358540 V. INSTRUCTION DESCRIPTION (33) A further object of the present invention is to develop a method of characterization for the purpose of studying and characterizing differences in chemical composition in biological samples. A further object of the present invention is to create a vast database that will provide a number of generalizations for the efficacy of a particular group of plants that are classified into one class by a particular disease or treatment classification. It is a further object of the present invention to provide a method for utilizing the conjugate and polar nature of a single component and the drug as a whole to understand and standardize the physico-chemical properties of the drug for use in conventional therapeutic methods such as color standardization. It is a further object of the present invention to provide a method for utilizing the conjugate and polar nature of a single component and the drug as a whole to understand and apply the drug to the physico-chemical properties of a conventional method of standardization such as taste, ie, acid. Salty, spicy, bitter, and astringent (as mentioned in Alla, Lavuna, Kathu, Ticta, and Caxia); Amla, Lavana, Katu, Tikta, and Kashaya) standardization. It is a further object of the present invention to provide a method for understanding and determining the physical properties of a drug, such as quality, efficacy, metabolites in absorption or such changes, and specific properties such as the optical activity of the molecule (eg, in Abu Dhabi’s mention of Guna, Vera, Wipaca, and Prabha

Page 37 1358540 V. INSTRUCTIONS (34) Standardization of cutting. A further object of the present invention is to provide a method for utilizing the properties of the single component and the overall car and polarity of the drug to understand and apply the drug to the physical chemistry of the conventional method of standardization such as heavy, light, cold , hot, gentle, smooth, dry, blunt, pointed (as in the Aluer, as described in Gulu, Lagu, Xita, Youxu, Sni Gododa, Manda, Tickerna; Guru, Laghu, Sheeta, Ushna, Snigdha, Manda, Teekshna) Standardization. In accordance with the above objects, the present invention relates to a method for using chromatographic characterization techniques for detecting and identifying extracts from plants or animals, natural or synthetic sources, the steps of the above method comprising at least: (i) a suitable solvent to extract the organic or organometallic molecule; (ii) subjecting the extract obtained in step (i) to separation analysis using high pressure liquid chromatography; (iii) according to p Η value and polarity The composition is used to generate contours and 3D tomograms; (i ν ) converts the resulting 3D and contour tones into color images, and uses the coordinates representing the three-dimensional nature of the color image to analyze individual colors in the image. By means of a built-in software; (ν) indicates the concentration of the different components that are rushed over time; (vi) the chromatogram produced by color analysis, with the presence of the common properties of the molecule Different retention time

Page 38 1358540 V. The absorption peak of invention (35); (vii) confirm the compound in the above composition with the UV-visible absorption properties of the different components in the image; (viii) hedge against polarity and coplanar nature The proposed compounds are identified, categorized and classified into polarity, medium polarity and low polarity or non-polar; (i X) produces a code with the X-axis as the residence time, the Y-axis as the wavelength, and R is the red image point (pi X e 1 s), G is the green image point and the B blue image point to represent the selected absorption peak; and (X) generates a database of features and barcodes and confirms the individual compounds in the sample. 5 - 4 Detailed Description of the Invention: Thus, the new basis of the current method is to propose a new method of characterization of the chemical properties of the chemical composition in the 3D and contour chromatograms. The chromatograms produced by this method provide the common and polar nature of the individual molecules in the therapeutic drug. In one molecule, the UV-visible absorption capacity of the molecule depends on the structure of the molecule. When a double bond or a triple bond of the molecule alternates in its structure, it is called a conjugation. If the molecule has more conjugation, the chemical and biological properties of the molecule will be more active. Therefore, if the molecule has more conjugation, the therapeutic activity is stronger. Therefore, the measurement of the conjugate nature will provide the efficacy of the drug. Therefore, the use of this conjugated property as a standard of treatment is a new aspect of the present invention.

Page 39 1358540 V. Description of invention (36) Dependence. A new method for quality control of herbs and formulas that facilitates the characterization and standardization of traditional drugs (chemical and therapeutic), unlike the methods used today to analyze a single active component of a drug at a single wavelength (not yet Know that it exists in many herbs). The method provides an overall overview of the chemical composition of the conventional drug as the physical and chemical properties of the compound (referred to as UV-visible absorption characteristics and polarity). In the first part of the method, an image of the drug signature will be produced. However, because images cannot be transformed into analytical data, a computer-based approach is developed to provide qualitative and quantitative data for the constituents in the form of an analytical chromatographic report. This method is also proposed as a novelty of the method of the present invention. The activity of any molecule will depend on the number of double and triple bonds in the molecule along with the position of electrophilic and nucleophilic on the molecule. The provision of electrons and electron accepting will create a difference in the total electron valence of the molecule. This phenomenon turns the molecule into polarity. Thus the polarity of the molecule will provide information about the ability of one molecule to provide or accept electrons with another molecule. This ability will control the activity of the molecule. Therefore, a molecule of polar data will convey the activity of the molecule. In the proposed method, the chromatogram proposed by this method will provide the properties of the conjugate and polarity of the components in a drug in the characterization. Therefore, this method is used for the standardization of drugs to understand the efficacy of the drug by using the conjugate and polarity properties of a drug. This is the novelty of the proposed method.

Page 40 1358540 V. INSTRUCTION DESCRIPTION (37) As noted above, the UV-visible spectrum and polarity of the compound will indicate the co- and polar nature of the compound and thereby indicate the chemical/medicinal properties of the drug. The spectral profile of all the components in a single picture, as proposed now, is characterized by a blueprint for the presence of the ingredient in herbs and recipes. This blueprint becomes a superior method to the identification and standardization of herbs, because the absorption peak will indicate the UV-visible nature or the conjugate and polarity properties of the component, unlike a common chromatogram taken from a single wavelength. Along with the quantification of this component. The color of the drug can be used to understand and standardize the efficacy of the drug as described in conventional standardized methods. The color of the molecule can be understood by the absorption characteristics of the molecule in the ultraviolet-visible radiation range. The absorption of a particular wavelength is based on the structure of the molecule, the functional group, the conjugate nature and the degree of unsaturation. If the conjugated nature of the molecule is greater, the longer the wavelength the molecule will absorb. Therefore, UV-visible absorption of any molecule is widely used in the qualitative and quantitative properties of the composition. The color and efficacy of various drugs have been provided in ancient literature. Finally, the color of the molecule is due to a particular chemical nature of the molecule. This chemistry can also be understood when studying the same characteristics. The colors of the ancient flames were used for quality control of metals and related products, including spectrophotometric principles. Therefore, studying and understanding the role of this electromagnetic radiation will help to study the drug.

Page 41 1358540 V. The chemical nature and efficacy of the invention (38). The same principle has been used for characterization and standardization of existing spectrophotometric methods. The main novelty of this proposed method involves the distinction between the characteristics of wavelengths (conjugation) and residence time (polarity) into different treatment areas to understand the efficacy of a single or formulated drug (as is conventional). Use an instrument and software application program. Using the developed software for using a computer, a code is created to represent the selected absorption peak of a molecule in the provided image. Where X is the residence time, Y is the wavelength of the contour chromatogram and the absorption in the 3-D chromatogram, R is the red indicating the highest concentration of the component, G is the green indicating the lower concentration of the component, and B is still It is pointed out that the lower concentration of the blue component of the component is provided by the proposed software to satisfy any commercially available resaleable bar code making software, and the existing software can generate a code for a single component or for many components. . An image of the feature can be viewed on a display window attached to the bar code. This information will be displayed whenever the electric eye of the vending machine reads the bar code. This feature has been required to be another novelty of the method of the invention. When the polarity of the column is fixed and the polarity of the moving phase is continuously changed in increasing or decreasing order, on a reversed-phase column, the components in the sample will be the first with the highest polarity and the middle polarity. The composition is followed by the order of the non-polar components. It should be noted that in the process of extracting the component, the order of increasing or decreasing polarity makes the component without any polarity finish.

Page 42 1358540 V. INSTRUCTIONS (39) After the total flushing, it remains in the column. This order and polarity can be applied to the reverse chromatography column as well as in the forward chromatography column, but it must be reversed. In a forward chromatography column, the non-polar component will be the first to be followed by a polarity component, according to the polarity sequence of the mobile phase used in the flush. Therefore, an evolving feature that aligns chemical components in increasing or decreasing polarity order will help to generalize the treatment of the drug. This is another novelty of the proposed method. The image of the contour tomogram developed after this analysis was divided into three regions on the X and Y axes. The conjugated property (radiation absorption at a particular wavelength) is placed on the Y-axis and the polarity is placed on the X-axis, with the polarity of the composition being controlled by the polarity of the composition. The unit of the Y-axis is now reported in the literature according to its efficacy, which is based on wavelength (color). All images are divided into six spaces in which the chemical composition has a special conjugate and polarity properties. This property is in turn proportional to the therapeutic effect of the components in this space. That is, when a drug characteristic is identified, the color of the particular wavelength is expressed in accordance with the color of the appearance and has a particular polarity, and the overall color in the area is calculated and interpreted as the therapeutic effect of the component in the drug. Therefore, standardization of all therapeutic effects and chemical standardization can be accomplished using this method. Most of the sample flushing is done from a high polarity phase to a low polarity phase. So appear in the first zone (Ζ ο n e - 1 ) in the characterization of the component

Page 43 1358540 V. The composition of the invention (40) will be highly polar in nature. The same mode is applied to other areas, the medium polarity component is flushed to the medium polarity zone (Zone-2) and the low polarity or non-polar component is flushed to the non-polar zone (Zone-3). When a forward chromatography column is used, the appearance of the characteristic of the component will be reversed due to the polarity of the extraction as described above. Most of them enter the decontamination system and carry out different Vipaca. In the process, the main part of the intestine part of the transient system acts in the body, the highly polar southern polarization system and the enzyme changes in the part. It should be classified as follows. The first part of the molecule that thermally deduces a heavy molecule appears there (the activity that occurs later in the aspiration (highly effective. Pita area) the role of the reaction machine. High chemical mouth When, then, the fraction of the action, digestive juice and sex can be compared to the high-polarity of the structure, which will indirectly refer to the immediate opening of the component with the organism will be in the Ayou enzyme. In response to the activity of the sub-reaction, the patient enters the stomach. In the beginning of the inhalation, the relationship between the child and the child is the sex. In the intestine, the life of the person, the performance of the person’s life is absorbed. After that, the blood with the absorbed component will carry it to the heart and the organ connected to the heart. The blood will then be sent to different organs of the body. In Ajal, the higher part of the human body is defined as the card-emitting area. The cold institutions there will play an important role. Therefore, the polar molecules will play an important role in the institutions associated with the region.

Page 44 1358540 V. INSTRUCTIONS (41) The low polarity and non-polar components will only be transported through the blood into the body. Therefore, an organ in the body that can only obtain the chemical component by blood will become the last species of the polarity. The non-polar oils, fats and other such molecules are classified as stalks in the body and all such disorders can be treated with the same type of material. The low polarity and non-polar components will be flushed to the last region of the feature. Therefore, the area (the third zone) is considered to be the pagoda zone. Therefore, the basic properties of a molecule can be classified according to its polarity, helping to understand what kind of disorder the molecule will act on. Therefore, the recommended method contributes to the standardization of drug treatment. Therefore, the entire composition appears in the Pita District of the first district, the second zone, and the third zone of the pagoda zone appears in a pie chart indicating the proportion of the drug in each of the disorders. Therefore, the drug has a ratio of 50:20:30, which will be a 50%: 20%: 30% ratio of the Iduzahira drug. Therefore, the efficacy can be standardized in quantity. The increment or decrement of any one or two of the other summers can be accomplished by formulating the drug via the addition of other drugs and making a suitable formulation suitable for treating a particular individual. Therefore, a feature with a conjugate size, absorption and polarity of the 3-D layer will provide information about the efficacy of the drug. The 3-D chromatogram of the drug is quantified using the properties of the so-called three-dimensional image of the image. For example, if the 3-D chromatogram is considered as a ‘capped hat cap

Page 45 1358540 V. Description of the invention (42) with a hood'), the three-dimensional combination of the entire hat, there is another sample of different qualitative and quantitative properties, the suitable range will be described as a certain and quantitative analysis report. Here the headscarf of the hat is used to compare the absorption peak of the molecule at a particular wavelength. A sample with many numbers would resemble a hat with many headscarves. Therefore, the cooperation of the three-dimensional coordinate axis will provide a very simple comparison and analysis method. This suitable coordinate axis will provide qualitative data and the appropriate range will provide quantitative data for the sample in the study. This phenomenon is made possible by special software made for this project. This method becomes a fundamental method of quality control. This method is another novelty of the method of the invention. The invention is also related to a software on a data processor for a 3-D chromatogram and a color contour image of a composition comprising an estimation tool and having the following capabilities: a. - analyzer (excerpt) Color) Regarding the analysis of the color contour image according to the selection of various colors (having the standards mentioned in the published notes, life cycle, processing) to indicate the concentration of various components that are rushed over time and according to the residence time Polarity; b. - analysis of the 3 -D chromatogram of the drug using all of the three-dimensional properties of the image; c. a tool for producing a molecule with a number of molecules that rush over time with a well-defined polarity order a conjugated property of a chromatogram of absorption peaks at different residence times; d. an identifier for confirming compounds in the above molecule by

Page 46 1358540 V. INSTRUCTIONS (43) UV-visible absorption properties of different components in the image; e. - The tool divides the features into therapeutic regions on the X and Y axes according to the polarity and conjugate properties of the molecule The nature of the treatment of the various components of the study drug, the nature of the treatment; f. A tool for generating a code representing a selected absorption peak using the image coordinate axis, that is, X is the residence time, Y is the wavelength , R is the number of red pixels, G is the number of green pixels, and B is the number of blue pixels, provided by the program's software; g. - the tool is about generating a database of features for the sample and Sample barcodes, facilitating the application of various functional databases such as enterprise resource planning and customer relationship management; and h. — tools for generating a 'display window' database for all of the enterprise resource planning and customer relationship management Type of commercial application. The acronym ERP used in this patent document: Enterprise Resource Planning CRM: Customer Relationship Management UV-Visible: Electromagnetic radiation in the range of 200 nm - 800 nm. Organic molecule: An organic molecule, a molecule having the basic elements of C, Η, N, 0, S in its structure.

Page 47 1358540

Organometallic molecule, a basic element of H'N, 〇, s, 0rgano-Me ta 11i c molecule has a metal in its structure accompanied by C, rimography, a chromatographic spectrum, ruthenium 4 Detector (P hot 〇D iode # 1 to range from 2 0 0 nm - 800

Contour Chromatogram: The data is generated from an optical dipole Array Detector (PDA), which is used to scan the sample. The resulting chromatogram will be mentioned

The residence time for the absorption in the X-axis '(10) range is on the γ-axis. Different colors will be used to indicate different concentrations of the individual ingredients. 3-D chromatogram: A three-dimensional chromatogram, generated using the same equipment as above. There is more information about the UV-visible spectrum of each component separated from a mixture. Helps to use the spectrum to identify its composition

Ayurveda: An Indian philosophy written by Indian sages that explains the systematic science of medicine and health training.

Oshadisukta: A chapter in Regal Vida that provides the detailed nature of drugs that have been used as medicine.

Rasa, Guna, Veerya, Vipaka, and Prabhava: the drug

Page 48 1358540 V. INSTRUCTIONS (45) The different physical-chemical properties of materials and materials can be used to understand the efficacy of drugs in Indian medical systems.

LokapurushaSamanya: Consistent original shell 1J in nature

Tri dosha: Three body fluids used to study the human body, namely the pita, the hairpin and the pagoda used in the Indian medical system.

Prakriti-Purusha: The first word is likened to 'nature' (woman) and the second word is the metaphor of 'person' (man) for the medical system of India.

Pi tta: - the name of the medical system used in India, which represents a body fluid in the body of a medical system in India to indicate that its character or disease exhibits the function of the digestive and chemical or general Reesalia in the human body. .

Kapha: The name of the medical system used in India, which represents a body fluid in the human body in India to indicate its character or disease. This factor provides shape, stability, and cohesion and lubrication in the human body.

Vata: The name of a medical system used in India that represents a body fluid in the human body in India to indicate that its character or disease exhibits this neurological, endocrinological and neurological activity in the human body.

Page 49 1358540 V. Description of invention (46)

Geological factors: Global differences in the nature of the soil and the composition of the groundwater, etc. on the composition of the Earth.

Ecological factors: Global differences in tropical regions, Indian monsoon environments and temperatures. »

Organoleptic methods: Identification of the nature of the drug such as 1. taste (such as acid (Allah), salty (Lavalna), spicy (Catu), bitter (Ticka), 涩 (Cascia) 2. Color , 3. Aroma and 4. Texture, etc., using organs that humans feel. Sexology - ο I 匕 66 τ to Guan Lie sense is the sense of field 撒 撒 兹 卜 卜 寸 寸 寸 寸 寸 寸 寸 寸 寸 寸 寸 寸 寸 寸 寸 寸 寸 寸 寸 寸 寸 寸 寸 C C C C C C C C C C 味Geologically explicit and identifiable, the quality of the substance, and the neutralization of the drug. The standardization of the drug is to use its properties such as taste (Rui Sa), quality (Guna) effectiveness (Veliya), The state after assimilation and the influence of this component (Vipaka) and special effects (Pulaberhaval).

Saptadha tus: seven elements such as Russell (body's secretion), Rakta (blood) 'Mansa (Mamsa), Muscle (Majja, bone marrow), Aspir (Asthology) Medas (fat) and Shukra (reproductive) ingredients have been used in the human body in India. ;

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Panchbhutas: Five natural elements such as Prithivi (Earth), Epp (Ap, Water), Iron (Teja, Fire), Vayu (Vayu), and Akasha (Akasha, Empty) exists in the medical system that has been used in India on Earth.

Nadisastra: A science that explains the health of the human body and has been used in India's medical systems to study people's pulse. In India's medical system, the factors that cause disease can be explained by Agantavaha (unexpected), Sharirah (Sarirah, body-generated), Manassa (Manaasah, psychologically produced) and Swah. Bobhavikah (natural). Diseases can be divided into three categories as each Indian medical system. They are treatable (Shandhi, Sadhya), moderate or controllable (Yapia, Yapya) and incurable (Ashandhya, Asadhya).

Conjugative property: A phenomenon in which a molecule has a single bond and a double bond with the error and the nature of electron supply and acceptance. This phenomenon is called a common vehicle. This phenomenon can be seen in the ultraviolet-visible spectrum of one molecule. According to the energy absorbed by a molecule of sigma and pi electrons from the excitation of this electromagnetic radiation, the molecule will absorb a particular wavelength of radiation. The maximum absorption of this molecule will therefore indicate the conjugate nature of the study molecule.

Page 51 1358540 V. Description of invention (48)

Polarity property: Polarity, if a molecule differs in its electrochemical properties, it is called polar. It depends on the atom belonging to the molecule having a moiety (electrophilic) or accepting an electron (electrophilic) or a g-group having a difference in the number of electron valences in its molecular orbital domain. This causes the molecule to have a positive endpoint and a negative endpoint. Such molecules are called polar molecules. The range and type of the electronic valence will cause the molecule to be polar, medium-polar or non-polar.

Gradient or ternary system of HPLC: - HPLC instrument having two or three liquid phase pumps to vary the ratio of the aqueous or non-aqueous solution. This will help control the overall polarity of the phase through the instrument. Abbreviations in some software: J D K . J a v a development kit (java development kit)

Con: contour chromatogram (c〇nt〇ur Chromatogram) 3 — D: di-unary chromatogram (3_j) imenti〇nal Chromatogram) WOS: /With units (Without Scale) X : indicates the chromatogram Retention time Y: indicates the absorption in the 3-D chromatogram and the wavelength range in the contour chromatogram R: the red intensity G at a particular image point: the green intensity B at a particular image point : Blue intensity at a special image point location

1358540 V. INSTRUCTIONS (49) EXAMPLES One embodiment of the present invention relates to a method for chromatographic identification of features, chemical and therapeutic standardization from a plant, animal or a naturally available or artificial The bar code of the organic and organometallic molecules of the manufactured materials is made. Another embodiment of the present invention relates to chromatographic identification of a novel method for use in the characteristics of herbs and formulations. The method can eliminate the disadvantages of the prior invention. A further embodiment of the present invention relates to a method for A complete analysis of the composition of the study drug and the conjugate nature of the component indicate the efficacy when the traditional component of the drug is developed with new software. Still another embodiment of the present invention is directed to a practical method for the characterization of a drug characteristic for the actual profile of a drug component and the consequent rapid identification of the component's therapeutic effect. Still another embodiment of the present invention relates to a new concept of chromatographic identification of the characteristics of the herb and the formulation using the profile and 3-D chromatogram proposed by the herb and the formulation. These chromatograms were developed on an optical dipole array detector of a high pressure liquid chromatography. The chromatogram is a description of the spectral properties of the herbal component that was formulated under the analytical conditions of the experiment.

Page 53 1358540 V. INSTRUCTION DESCRIPTION (50) A further embodiment of the present invention is directed to the use of chromatographic characterization from a drug extract. The drug contains any molecule that absorbs radiation in the ultraviolet and visible range (200-800 nm) or any range of electromagnetic radiation. In another embodiment of the invention, the ultraviolet-visible spectrum of the compound provides a co-roll of the molecule. Nature and individual concentrations of the molecule. In another embodiment of the invention, the development of a feature of the same drug at different pH values facilitates understanding of the release of the drug in the intestinal system of a different pH value of the body. In still another embodiment of the invention, the ultraviolet-visible light spectrum of all of the components has been shown in a single image π-chromatographic feature ". In still another embodiment of the invention, the feature becomes a blueprint of the composition of the herbal or formula as a test and rapid identification of the study drug. In still another embodiment of the invention, the use profile and the 3_D chromatogram are characterized by the identification of existing and/or newly formed chemical constituents. In still another embodiment of the invention, the ultraviolet-visible light spectrum and polarity of the component indicate the co-roller and polar nature of the compound thereby indicating the drug

Page 54 1358540 V. INSTRUCTIONS (51) The chemical-medicinal properties of matter. The spectral profile of all components in a single image, "characterization" is now a blueprint for the composition of a herbal or formula. This becomes a better method than the identification and standardization of existing herbal medicines. When the absorption peak exhibits the ultraviolet-visible nature or the characteristics of the composition or the co-vehicle and polar properties, it is not like an ordinary chromatographic spectrum. This component is quantified by a single wavelength. In still another embodiment of the invention, the feature is differentiated into different treatment regions based on the wavelength (co-consumption) and residence time (polarity) to understand the efficacy of a single or formulated drug (as is conventional)完成 It is done by using an instrument and a software-using program. In still another embodiment of the present invention, a large database of plants prepared using the method provides a number of generalized effects of a particular group of plants, and is effectively classified into a group of specific diseases. In still another embodiment of the present invention, 舴X, Y, R, G, B is taken as a coordinate axis of an absorption peak selected in the feature, and a code is generated by using a code making software, the barcode making the drug Ownership belongs to a business In yet another embodiment of the invention, the 3-D chromatogram of the drug is used for all three-dimensional properties of the image. If the 3-D chromatogram can be considered as a hat with a headscarf, the three-dimensional fit of the entire hat has another one.

Page 55 1358540 V. INSTRUCTIONS (52) For samples of qualitative and quantitative nature, the appropriate range can be described as a qualitative and quantitative analysis report. Here the headscarf of the hat is used to compare the absorption peak of the molecule at a particular wavelength. A sample with many numbers would be similar to a hat with many headscarves. Therefore, the cooperation of the three-dimensional coordinate axis will provide a very simple comparison and analysis method. This suitable coordinate axis will provide a qualitative and suitable range that will provide quantitative data for the samples in this study. This phenomenon was made possible by the special software made for the plan. This method becomes a fundamental method of quality control. In still another embodiment of the present invention, a novel method provides a chromatographic identification of the characteristics of the herb and the formulation using a profile and a 3-D chromatogram of the herb and the formulation. These chromatograms were developed on an optical dipole array detector of a high pressure liquid phase analyzer. The chromatogram is a data describing the spectral properties of the herbal ingredients that were formulated with a particular polarity under the analytical conditions of the experiment. In still another embodiment of the invention, the use of the ultraviolet-visible spectrum of the compound provides conjugate and polar nature of the molecule and provides individual concentrations of the molecule with the polarity of the molecule. In still another embodiment of the present invention, a method is provided for providing an ultraviolet-visible light spectrum of all components displayed in a single image "chromatographic feature". This feature thus becomes a blueprint for the ingredients of a herbal or formula as a test and rapid confirmation of the study drug.

Page 56 1358540 V. INSTRUCTION DESCRIPTION (53) In still another embodiment of the present invention, the features of the contour and the 3-D chromatogram are used as the basis for the identification of the chemical composition to define the scope of the invention. In still another embodiment of the present invention, a method has standard analytical parameters such as extraction with an ethanol solvent, maintaining the same extraction time of 0 -6 0 minutes, using the same mobile phase acetonitrile and pH. The phosphate buffer solution at 5.5 - 7.5, and the same UV-Vis wavelength range of 200-800 nm. In still another embodiment of the invention, a method uses standard analytical parameters such as ethanol solvent to extract all samples as a characteristic treatment of a particular treatment population of the sample to establish a standardized treatment. In still another embodiment of the present invention, a method for identifying characteristics of a noisy food, drug, and chemical sample is confirmed and the pure substance and impurities are confirmed. In still another embodiment of the present invention, a method for identifying characteristics of a substituted food, drug, and chemical sample is identified and the pure substance and the substitute are confirmed. In still another embodiment of the present invention, it is a method for identifying characteristics of a commercial sample of a food, a drug, and confirming the pure substance and the substitute.

Page 57 1358540 V. INSTRUCTION DESCRIPTION (54) In still another embodiment of the present invention, a method for identifying characteristics of organic and organometallic components in various samples to confirm chemical composition therein for various quality control The purpose and process are standardized. In still another embodiment of the present invention, a method for characterization is used for anti-therapeutic therapy, Ayur's, homeopathic, Seadha, Younani, China, Tibet, Kanpo (曰本Drug samples as standardization for their quality control and chemistry and treatment. In still another embodiment of the present invention, a method for characterization is used to study and identify various naturally occurring chemical components and to normalize chemical components therein. In still another embodiment of the present invention, a method for characterization is used to study various naturally occurring chemical components and to confirm that the differences caused by their chemical composition due to geological and ecological changes are standardized. In still another embodiment of the present invention, a method for characterization is used to study various naturally occurring chemical components and to identify and normalize differences in their chemical composition due to genetic and phenotypic variation factors. In still another embodiment of the present invention, a method for identifying a feature

Page 58 1358540 V. INSTRUCTIONS (55) Use to study the chemical composition of the synthesized samples and to identify the parts that have been applied to the chemical and therapeutic standardization of their chemical components. In still another embodiment of the present invention, a method for characterization is used for the study and identification of chemical constituents in single and multi-drug formulated herbal medicines as standardization of chemistry and treatment. In still another embodiment of the present invention, a method for characterization is used for the study of the difference in chemical composition in a biological sample and to identify and normalize the chemical components therein. In still another embodiment of the present invention, a method for characterization is used to study the differences in chemical composition between single and formulated food and drug samples of different trademarks and to identify chemical components therein as standardization of chemistry and treatment. In still another embodiment of the present invention, a method for making a database provides a plurality of generalizations of the efficacy of a particular group of plants, and is classified into a classification as a particular disease or treatment. In still another embodiment of the present invention, a method for developing a feature identification and classifying it with a drug component is quantified based on polarity and a total of from a 3-D and rim chromatogram.

Page 59 1358540 V. INSTRUCTION DESCRIPTION (56) In still another embodiment of the present invention, a method is provided for providing a code to a selected absorption peak of a molecule in the image, wherein X-residence time, γ_wavelength, The number of red image points, the number of G-green image points, and the number of β_blue image points are provided by the current computer (Microchip, Dongle switch, hardware and software locked) software, and satisfy any commercially available The resulting resaleable barcode making software is present in the proposed software to produce a single code. Some examples of images show the coordinate axis X-residence time of a particular absorption peak, Υ-wavelength, the number of R_red image points 'G - the number of green image points and the number of B-blue image points' are unique to the product And the resulting barcode is closed. In yet another embodiment of the present invention, a method is described for making a database of one code such that the development of the feature facilitates the application of various databases. In still another embodiment of the invention, all of the characterized samples have been developed. All details such as 3-D and contour features of the country), manufacturing period 'expiration', its test, production serial number, and information on the label. When the label is displayed on the additional display window. The application helps to understand that the drug is a method in a further embodiment of the invention, which helps to display the sample in the "display window" The 'bar code, the source of the details (factory or 'reported Du Xia' individual use of the object number, MRP and any of the bar code displayed in front of the vending machine, will not show up in various management and things The conviction of chemistry and treatment is addressed in an application that attaches barcodes to the data and sources of the display window.

1358540 V. Description of the invention (57) Display window. In still another embodiment of the present invention, a method of creating a database of display windows is generated and attached to respective barcodes for use in enterprise resource planning and customer relationship management applications for all of the databases. Commercial online transactions of drugs and samples. In still another embodiment of the present invention, a method of making a database of codes and display windows and any information, particularly the management authority necessary for the import and export control of the drug in the country. In yet another embodiment of the invention, a method for identifying features can be used to understand and standardize the physical chemical properties of the drug, such as color, as a standard for chemistry and treatment of drugs and body fluids. In still another embodiment of the present invention, a method for characterization is used to understand and physico-chemical properties of the drug such as taste (Rousse) such as acid (Allah), salty (Lavaline), spicy ( Kathu), Bitter (Ticka), and 涩 (Kashaya) are standardized for the standardization of chemistry and treatment of drugs and body fluids. In still another embodiment of the present invention, a method for characterization is used to understand and physical chemistry of the drug such as cold, hot, slow, strong, heavy, light, soft Smooth, supple

Page 61 1358540 V. Description of the invention (58), dry (Guna's such as Xita, Youxu, Manda, Ticker, Gulu, Lagu, Sni Goddah, and Luksha (Rooksha ) as standardized in Ajal, as standardization of the drug treatment. In still another embodiment of the present invention, a method for characterization is used to understand and analyze the physical chemistry of the drug, such as potency, absorption metabolism, and special properties such as Charlotte of the molecule (C har 1 〇 11 e, explained as Vera, Vipaca and Prabhavar as a standard for the chemistry and treatment of drugs and body fluids. In still another embodiment of the present invention, a data processor for providing a soft contour image and a 3-D chromatogram based on a composition is provided. The method of the invention is described in turn in the subsequent tables, figures, flowcharts and examples. The above is only the preferred embodiment of the present invention, and is not intended to limit the scope of the present invention; all other equivalent changes or modifications which are not departing from the spirit of the present invention should be included. Within the scope of the patent application. The invention is described in detail with reference to the accompanying drawings, the drawings, and the accompanying drawings, and the description of the invention. Method of chemical standardization:

Page 62 13!) 854〇, invention description (59) Therefore, unlike the current method, one chromatogram provides only strip conditions: two wavelengths, a new method of chemical standardization, providing features铿Set and =, use 3-D and contour image. This method provides a complete chemical profile of the complex drug and the chemical composition of the formulation or any drug | such as & polarity ^ and * conjugate properties. Furthermore, the characterization will result in a number of commercial features in dealing with such drugs used in enterprise resource planning and customer relationship management applications. Relationship 6 can only be used to develop a layer in its various mass spectrometers. Therefore, the help of $ expensive technology in a special: m a chromatographic feature tlc # levy identification method, as shown in Figure 4, 'inspection of a component. This method does not provide any & co-consumption or polarity. Another-characteristic method, with HP = 2 瑨 at one wavelength in the morning can be described as the "layer 2" of the drug, - the selected absorption is chemically confirmed by the same : characteristics: analytical techniques such as nuclear magnetic resonance spectroscopy (阙, liquid Phase:: (LC-MS) and far-outline spectrometer (IR) as its knot 2 The single chromatogram cannot be explained in other no more expensive conditions. In this case, the drug is only explained by itself: two m miscellaneous Herbs and a variety of organic and inorganic drugs::: 疋> The formulation for oral use will be very impractical, and the quality of any formulated drug will be based on the pharmacy or pharmacist. For the 3:, the process, what is actually needed is a quantity that can be provided in a single:: or two: quality control (quantitative and qualitative), and the composition of the study T. Simple treatment

1358540 V. Description of invention (60) Analysis method. Therefore, any method that does not provide the above information is incomplete. In the chemical standardization method of the present invention, the component is first extracted into a suitable solvent. The extract was separated into individual components by a high pressure liquid chromatograph under standardized analytical conditions. It is then converted into a tomographic image by the 3-D and contour chromatograms provided by the instrument. The image is analyzed using image analysis software specially created for the analysis of the image. This output data can be used to illustrate the above standardization. A detailed description of the method has been presented to the experimental description of the method. Standardization of treatment: The standardization of this traditional treatment, according to the doctor's ability and preparation, is highly individualistic. The general availability of such methods will actually be difficult. But the existing scientific scheme emphasizes that any method or institution needs to be standardized and reproducible. Therefore, in today's standardized methods of chemistry and treatment, an instrumentation method is proposed to reduce human factors. This is made possible by an instrumental analysis that explains the chemistry and therapeutic utility of the drug being studied in a simple way. In most modern scientific scientific and organized societies, knowledge of the efficacy of the drug must be interpreted in a reasonable-defense rather than individual techniques and abilities, as it varies from individual to individual and is not reproducible. The idea of the method of the invention is likewise not divorced from the conventional concept.

Page 64 1358540 V. INSTRUCTIONS (61) As described above, the evaluation of the drug can be performed by physico-chemical properties (polarity and co-consumption: standardization of the treatment::: The activity, thus achieving the quality can be considered in the d:: method, the conjugate and the polarity of the τ estimate - the effect of the music. In ancient physics, a chemical, structure, odor is completed. Table 8 how the color makes the soil The composition of the species and the efficacy of the medicinal plant is based on the quality of the literature and the plants in which the needles can be collected, and used in the age of the land to be affected by the objects. The homology point, for a soil effect, the color of the 0 diverse and clear and collected a clear classification of the soil and plants has been proposed according to the guidelines. According to the guidelines, color selection for a particular disease has been different The influence of the body part shows that the sex is also mentioned when selecting a drug. The influence of the climate is mentioned in the medicinal use. Because the chemical ecology in the plant is different, it refers to The time of the guide (seasonal and daily) and the need for special treatment functions. According to the plants that have been used for common disease types, the plants can be divided into 3 categories (Sas Lushan's wealth, κ · Η. Krishna Moss, India's Ayur, the Institute of Research's Coimbatore, India - originally from the Susluta Samhaita Tatras 38 () Wealth of Susrutha, Κ. Η Krishnamurthy, Indian Institute of Ayurveda, Coimbatore, India—originally from Susruta Samhita suhasthana 3 8). Therefore, such plants must contain chemical components with similar therapeutic effects on the reported disease.

Page 65 1358540 V. INSTRUCTIONS (62) When studying different types of features, some common features about the efficacy of the plant can be found. This same utility is also reported in the traditional literature. In other words, the results of this experiment are the same as those reported. Therefore, the study of different drugs has different effects to confirm the method.

Figure 13 presents all yellow color drugs. All of these drugs are classified into the genus Haridra in the ancient literature of Ajal, and all these two-kappa drugs are similar in color to turmeric. When this feature was studied, it was found that these drugs have been reported to act as Kahera, a disorder of damage related to the body's mucogeneous composition. Therefore, it is understandable that the color of the drug is directly related to its therapeutic effect. In terms of rationality, the effect of this color and the drug is due to its chemical composition and its physical-chemical properties. β Hai single drug such as valerian, Saraca Indica, Hu Huanglian 'P hy 1 1 anthus N iruri and formula such as & Roggia Verde Hauni (A rogya V ardhini ) and Avipattakara Churna have been shown in FIG. The molecule raised to the first region by the β indicates the presence of a polar component in accordance with the elution pattern of the set analytical conditions. One of the general trends in the drug's extraction pattern has been reported to be Pitta Hera, which confirms that the action of this highly polar component is mainly similar to Pitta Hera.

Page 66 1358540 V. INSTRUCTIONS (63) The characteristics of this single drug, such as Zinziber of f icinal is (processed), innula racimosa ), Sausserea Lappa St. Basil's Glycerzia glabra and Xu Lajit were reported as Kahra. The elution to the second region of the molecule $ out of the presence of polar components. A general trend that has been reported as a mode of extraction for Kapela drugs confirms that the role of the medium polarity component is similar to that of Kapela as shown in Figure 15. The single drug such as galangal, ramie and formula such as Survarna yogara ja Guggulu, Brihatvata chintamani has Svalnamark Exploration (swarnamakshkam) 'Huthasana and Mahayogaraja Guggulu have been shown in this. The molecules eluted to the third zone indicate the presence of very low or non-polar components based on the scoping of the set analytical conditions, which are mostly oily in nature. It can be observed that any drug used in the disorder contains or is mixed with oil, and the type of oil of the component, the organometallic molecule 1 of the herb's mineral has been extracted into the region and has also been found in Huata, which can be reported. A general trend in the extraction mode of the felled Tahra drug confirms that the action of low or non-polar components is mainly similar to that shown in Fig. 6.

The single drug, such as the Indian elm, Curcuma i〇nga, Holarrheaana

Page 67 1358540

V. Description of invention (64)

Antidyssentrica), Psoralia Cordifolia and Citrullus Colosynthis have been shown in this figure. The molecules eluted to the first and second zones may indicate the presence of highly polar or medium polar components. Therefore, these components with medium polarity have been found to be Pita-Kafahra. This phenomenon confirms that the efficacy of the drug can be understood by the polarity of the components therein, as shown in Fig. 17. Characterization of the single drug, such as 蒺Cai, Moringa, Dipping Sauce and formula such as Trikatu, indicates that the effects of the ingredients present in the second and third zones are essentially similar to those of Kafka-Vatahra,丨8 has the same explanation. Characterization of the single drug, such as Pseudomonas, wood butterfly and formula, such as Kanchanara Guggulu, indicates that the effects of the components present in the first and third zones are essentially similar to Pita Tatta In a formula called Knadabhairavi, 'Herweed' has been reported to have the effect of Pitavatta Hera but it can be found through the characteristics of the card. This phenomenon indicates that the artificial production of the drug did not successfully produce the drug with the desired efficacy. Therefore, the previously mentioned = method is useful in standardizing the process of making complex recipes. Figure 19 points out the same conclusion.特征 Characterization of the single drug, such as A1丨iuin Cepa, Withinia Pubiscence (red

Page 68 1358540 V. INSTRUCTIONS (65) Seed), Intralika Offiinaris and formulas such as Mahalakshmi vilas ras indicate that the ingredient is present in all three The full range of the polarities of the molecules present in regions 1, 2 and 3. This phenomenon indicates that it will belong to the promotion of Iduah Hera by efficacy. The presence of two similar forms of the molecule in the characterization of Mahaphra Verras is considered to be essentially isomeric. When such isomeric (geometric and optical) components are present, the Prabhavar effect is understood by the type of drug. Figure 20 shows the characteristics of all drugs that promote Idusha. Φ Kalimusali (Curculig0 〇rchi〇idis) and Safedmusali (Espargus Edelence) The characteristics of (Asparagus Adescendens) indicate that the two plants of different families can be divided into the same treatment group. This feature shows that the Yi-Du Chagha property is experimentally indicated in all three of the three regions with a slight difference in the same composition, as indicated in Figure 21. A single drug from two different sources is characterized by Citrulus Colosynthis for the provided Azur and homeopathic remedies. In the observation of this feature, a component containing three polarities can be found 'but usually a high polarity molecule is dominant. In the careful observation of this feature, it was found that the appearance and disappearance of the molecule at 12 minutes is the only difference between these images. The first drug tastes very bitter when compared to the other two. So some people have suggested using its taste as the efficacy of the drug.

Page 69 1358540 V. A trade-off of the invention description (66) is shown in 2 2 . This was the main method used in the #代文文, as shown in the figure, Lalina Antin took the Center 4 丄·"., w Rika (Hollarrena

Antidyssentrica), — μ ^ ^ α s is a collection of two different sites in a country, A , ^ 1L ^ ^ , which shows many different points. This is now! ^ ^ t 'Ecological, phenotypic and other causes of influence on the music, the influence of the thousands of knives, this phenomenon has been explained in Figure 23.

A huge difference can be seen in two beet le leaves from Andhra Pradesh and Calcutta, as shown in Figure 24. This phenomenon confirms the role of its geological, ecological, phenotypic and other variables in the chemical composition of the plant part. In Figure 25, India's ecological regions, rainfall, temperature and climate are shown to understand the ecological role of the seasons in flora and fauna. Changes in the season will cause an impact on the chemical composition of the herb and the drug will be produced. This phenomenon applies globally, whenever a herbal plant is harvested from different parts of the globe. Two formulations for cosmetics such as herbal shampoos are provided here. The characteristics of this pure herbal material are completely different from the characteristics of the dopant. Artificial detergents and foaming agents are applied at 25 to 40 minutes in the doped sample

1

Page 70 1358540 V. INSTRUCTIONS (67) It is clearly found that it is very alkaline and soapy in nature. This phenomenon supports the method of the present invention to assist the regulatory authority in testing the drug of traditional drugs containing dopants and substitutes, as explained in Figure 26. The characteristics of one of the two different trademarks, called 'Trichatu', differed in their assays. This phenomenon may be due to the fact that the treatment of a single drug can be used to prepare the formulation from different sources. This existing method exhibits a range of quantitative and qualitative differences that facilitate the preparation of standardized drug and herbal extracts, as shown in Figure 27. Formulations of one of three different trademarks of the same food material, such as turmeric, have been shown in Figure 28. In the characterization of the natural turmeric, the yellow curcumin molecule was found to be flushed at 20 minutes. This same molecule is commonly found in all trademarks. The difference in this profile is because the commercial sample is prepared from processed (cooked) turmeric underground stems from unprocessed (uncooked) underground stems. Figures 2-9 to 9 provide features developed from different drugs and the image parameters (height and rotation) have been used for the 3-D and contour chromatograms of the drugs in Table 13. In Table 14, the analytical drugs have been classified according to their efficacy. The analysis of the characteristics of individual drugs using the proposed software for analysis will support the utility of the patent claims in the treatment standardization of the present invention. This phenomenon confirms that this method contributes to many uses in the treatment of traditional medicines. For modern medicines, it is also helpful to understand its traditional efficacy.

Page 1358540 Barcode Production 'Enterprise Resources In the current method, the software is divided into residence time, Y is the wavelength, the number of points, and B is the blue image point spectrum and uses the software of the computer (hardware and software specific absorption peak. When The data is resold by a random image point value in the bar code making software, and all the details of the product are studied. The method of the customer relationship management application analyzes the image and can show that the coordinate axis XR is the number of red image points. , G is the number of green maps. Now for a contour tomography Microchip, Dongle switch, locked), one of the unique features of the product has been converted/supplied to an original built-in, automatically from the image. Absorption bee

An additional 'display window' is generated with the code. The method of the β-the invention helps to barcode all the data of the components in the chromatographic features of an herb. 'Use X as the retention time, Υ as the wavelength, R is the number of red pixels, and G is the number of green pixels. And B is the number of blue pixels as the coordinate axis, which is provided by the software of the current computer (Microchip, Dongle ^witch, hardware and software locked) and the value of each component is provided by the current software. These factors will present the chemical and therapeutic benefits of the ingredient. Thus, instead of the bar code production that currently uses only the number of records, a new bar code making method is proposed here, and the coordinate values of the components will be displayed along with other details. Therefore, the bar code and coordinates will describe the chemical and therapeutic properties of the product. The method becomes a management authority such as a drug manager, a government analyst,

1358540 V. INSTRUCTIONS (69) Food Doping Executive, legal tool. And when it is inspected, it should be controlled by a differently labeled department and drug label of the same drug department center to how to provide a specific absorption value of the image to create a display code. Figure 9 5, 9 6 is how the window will display the bar code that the display window code will be able to represent. When a large amount of Internet access is available, any computer network uses enterprise resources to calculate what is needed for any enterprise resource planning, and when the data is drawn and used, the characteristics of the customer's herbal products can be printed. This method also has a screen. Figure 93 to the coordinates of the peak. The resulting strips of herbs are all marked by the display window add-on library for this product and customer relationship management. Figure 9 9 shows the management of the household relationship management in a standard to help a 9 4 statement will provide the code. The details of the logo are in the prepared application. The computer network should be on the goods tax and the factory monitors the software. These numbers are 97,98. This separate product allows it to be used by the network. The various steps of the present invention are used in current analytical methods - efficient high pressure liquid chromatography, a pump with a binary gradient system, an optical dipole array detector (PDA) and a software-using data. The processor is for the presentation of the chromatogram. After all the components have been completely flushed, the 3_D and contour chromatograms (with information on the UV-visible spectrum, absorption and retention time of all components in a single drug or formulation) can be converted into a proposal as a feature bond. image. This method enjoys the advantages of no internal or external standards for reliable qualitative and quantitative analysis of all ingredients in a drug, unlike current drug analysis methods.

Page 73 1358540 V. INSTRUCTIONS (70) Experimental Description of the Method: The recommended method can be described in four steps, with reference to the accompanying figures, flowcharts and examples, to illustrate embodiments of the invention, and The concept of the invention as embodied herein is not to be construed as limiting the scope of the invention. The entire method can be described as the steps mentioned below: Step 1: Drug selection and component extraction step 2: Separating the component into individual components and generating and converting the 3-D and contour chromatograms into features Identification Step 3: Analyze the feature using the developed software Step 4: Interpretation of the data Description of the current analytical method: Step 1 Sample preparation: Extract the ingredients from the drug using ethanol, based on the chemical nature of the sample ( Polarity) to select the solvent. When the pH of the aqueous ethanol extract changes, the extract of the component will also vary. The pH-acquisitive extract extracts more components than the acidic pH extract. Choose the appropriate pH to extract the different drugs and use a buffer solution to maintain a constant pH. Acidic and anatory roles must be considered when selecting the pH of the extraction. Step 2 Complete the experimental work on the instrument:

Page 74 1358540 V. INSTRUCTIONS (71) The extract was subjected to separation analysis using a high pressure liquid chromatography. In the current analytical method, an effective high pressure liquid chromatography is used, a pump equipped with a binary gradient system, an optical dipole array detector (PD A) and a software processor using software for this layer. The presentation of the spectrum. A sample of this extract (approximately 20 m 1 ) was injected into a syringe (suitable for a sample loop of 20 μm, 1 ο ο p ). The sample is eluted in a time-programmed gradient system of the appropriate phase, at a fixed flow rate (1 m 1 /m i η). It should be noted that no unexposed samples remain in the column. The analysis conditions of this flow are set for this analysis. Using a reversed-phase column, a phosphate buffer solution (pH range of 5.9 - 7.5) was eluted with a time-stylized gradient and a non-aqueous solvent was used according to the chemical nature of the sample ( Ethyl or sterol) as a rinse. A wavelength range of 2 0 0 to 800 nm is used in the PDA debt detector and the analysis time is fixed to be the same as the time program. This time program is used to change the proportion of organic solvents such as 0-100% of the non-aqueous solvent, which has been used in the instrument parameters of the instrument. The instrument was started immediately after the sample was injected into the syringe to analyze the sample. The program stops when the analysis is complete or the instrument will automatically stop when the entire time program is completed.

Page 75 1358540 V. Description of the Invention (72) In the three data display modes, the chromatogram, one window shows the chromatogram at a specific wavelength, and in another display the contour chromatogram shows The analyte retention time (analysis time) is on the X-axis and the wavelength range is on the Y-axis. In another window, the 3D chromatogram of the sample is displayed, wherein the retention time (analysis time) of the analyte is displayed on the X-axis, the concentration range is displayed on the Y-axis, and the wavelength range is displayed on the Z-axis. The 3-D and contour chromatogram developed by the system can be converted into an image. The resulting image is analyzed via a recommended software that provides a new chromatogram and qualitative and quantitative analytical data for the elements of the drug. The image point values are represented by different colors, from purple, ochre, blue, green, yellow, plucked and red, due to the quantitative determination of the concentration of the component proportional to the color. Each of the above colors is extracted and each color is represented by a different window. This method is the basis of chemical standardization. Some of the resulting chromatograms have been shown in Figure 1 0 0 - 1 0 2 . The resulting chromatogram also provides information on the conjugation of each component (expressed by the ultraviolet-visible absorption) and polarity by the software. The image can be divided into three regions, the first region (high polarity region), the second region (middle polarity region) and the third region (low or non-polar region), which are determined according to the retention time of the extraction mode. Scale, depending on the column used and its phase. If the analysis condition is reversed, the brewing mode can be reversed. The 3-D chromatogram of the drug will be analyzed using the three-dimensional nature of the above image. If the 3-D chromatogram can be considered as a 'headed hat',

Page 76 1358540 V. INSTRUCTIONS (73) The entire three-dimensional fit of the hat has a different qualitative and quantitative nature of the sample, and the appropriate range can be described as a qualitative and quantitative analysis report. Here the headscarf of the hat is used to compare the absorption peak of the molecule at a particular wavelength. A sample with many numbers would resemble a hat with many headscarves. Therefore, the cooperation of the three-dimensional coordinate axis will provide a very simple comparison and analysis method. This suitable coordinate axis will provide qualitative data and the appropriate range will provide quantitative data for the sample in the study. It is made possible by special software made for this purpose. This method becomes the fundamental method of quality control. This method separates the polar interaction of the molecule, and the polarity of the static phase used and the polarity of the phase used control the extraction of the sample to control the elution mode of the molecule. The effect of the internal combination of all three and other relevant parameters, such as temperature, determines the mode of extraction and the order in which the component is extracted based on its polarity. Therefore, all polar molecules in a drug will first be flushed to the 'first zone' (the polar region of the image), and all the polar molecules will be flushed to the 'second zone' (the middle polarity region of the image) and all Low or non-polar molecules will be eluted to the 'third zone' (the non-polar region of the image). When the molecule is extracted into these three areas with many characteristics, a number of generalizations that focus on the chemistry and therapeutic utility of the drug can be made. This is the basis for another standard of treatment. These areas have been significantly represented in Figure 10 3- 1 0 5 . Therefore, the chromatogram provides this information on how the chromatogram will function as a chemical and therapeutic. When individual ingredients are present in each area and vividly

Page 77 1358540 V. INSTRUCTIONS (74) Painted or represented by any data, the total composition of the respective area provides the percentage that will be applied to the particular summer. So the data explains how the drug will play a therapeutic role in the damage of each summer based on the quantitative and qualitative nature of the ingredients in the drug. For example, if the drug has 30% of the components in the high polarity region (the image points many different colors such as a specific region of green, yellow, orange and red as the amount) 70% in the middle polarity region can be expressed as a drug effect 3 0 secret Pita and 7 0 ° / on the card, as the color is represented as a different concentration in the feature. Therefore, a drug can be assessed as belonging to Pita-Kafahra (30-70%). Therefore, the damage of the summer has been quantified. This helps the doctor understand the effectiveness of the drug and determine its dosage. Some examples of pie charts have been placed in Figure 1 〇 6 - 1 0 8 . The reported 3-D and contour chromatograms of the herbs can be developed into reports for the analytical conditions. The thumbnail view of the drug shows how the characterization is controlled via a software because the software used to process the human features has been completed. All of this feature is suitable for searching for similar objects and comparing similar features, etc., by inserting the required software features. A sketch of the characteristics of the different drugs is provided in Figures 109-11. A list of drugs represented by this feature is set forth in Table 15. Step 3 Analyze the image using image analysis software: After completing the flushing of all components, the 3-D and contour chromatograms can be converted into images and proposed as features. The method can be enjoyed in a drug

Page 78 1358540 V. INSTRUCTIONS (75) The reliable qualitative and quantitative analysis of all components does not require the advantages of any internal or external standards, unlike current analytical methods. After developing the image of the 3-D and contour chromatograms of the study drug (hereinafter referred to as chromatographic characterization), the image can be characterized by different software for the analysis of the components by the recommended software. Quantitative properties to analyze. Scientifically, an image cannot be transformed into an analytical data, so a computerized image analysis software (protected software and hardware) is developed to analyze the software and appear in different residence times depending on the color of the component. And the image point value of the image to provide the concentration ratio of the components of the study drug. An image of this feature is now provided to the image analysis software as described above. The analysis of the different colors is represented by the absorption peak of the chromatogram to complete and thereby provide the chromatogram as a new one, presented in a colored strip pattern. The graph shows the amount of the compound and its conjugating properties, the UV-visible absorption properties of all of the proposed components. A detailed description of the process is included in the analysis of the image and has been discussed in the technical features of the software.

The strip pattern of the chromatogram thus developed provides a scale with a residence time (0 - 60) on the X-axis and a wavelength range of 2 0 0 - 800 nm at Y.

Page 79 1358540 V. INSTRUCTIONS (76) Chromatography on the axis. The chromatogram provides the number of pixels to be used for each color in the image in each of the images, aiding in the qualitative and quantitative analysis of individual components. Therefore, the resulting chromatogram is showing the number of components in a drug and its ultraviolet absorption range, and has a number of spots proportional to the concentration of the molecule. The image can be divided into three regions depending on the elution mode of the molecule and the change in its polarity. When the column used is a reverse phase column, the first zone is the polar zone, the second zone is the medium polarity zone, the medium polar molecules are extracted to the zone, and the last zone is the low or non-polar zone because Non-polar or very low polarity molecules will be eluted into this region. Therefore, the molecules that are flushed to the first zone will be polar, and the molecules that are eluted to the second zone will essentially be of medium polarity and the molecules that are flushed to the third zone will be very low in nature or Non-polar. Thus the three regions of the image will provide the polarity of all of the proposed components. Depending on the polarity of the molecule being clarified, the drug can be classified according to the traditional system of efficacy, which has been found to be Pita Hera, the medium polar molecule is Kahera and the very low or non-polar molecule It is Huata Hera. This is the basis for the standardization of the efficacy of the drug. The polarity of this component can be compared to a continuous spectrum of radiation, in which summer can be classified into a dramatic to chronic summer. The starting area is intense and the last area is chronic. Therefore, the compound appearing in the above region will act on the above disease strength.

Page 80 1358540 V. INSTRUCTIONS (77) Table 1 6 shows that the feature is differentiated into different treatment areas depending on the color and polarity of the absorption. The scale on the X-axis shows the polarity of the molecule according to the polarity of the phase, and the Y-axis shows the wavelength range of absorption (200-800 nm). According to the literature, the efficacy of different drugs is standardized based on the efficacy and experimentation of the physico-chemical properties (color and chemical properties). Some errors have been found to be due to the effects of different environmental factors affecting the chemical composition of the drug. Therefore, this method will help to understand the efficacy of the study drug. Therefore, the proposed method will become a novel and simple method to understand the efficacy of a reported or new or single or formulated drug. The analysis of this image was done using software developed for this purpose of analysis. Details of the software have been provided in the published notes and in Figure 115. Step 4 Interpretation of the data: The characteristics produced are analyzed to understand the nature of their chemistry and treatment. A basic feature of a feature can be found to be: 1) the polar region to which the component has been addressed; and 2) the conjugate nature exhibited by the individual component. The polarity of the column is fixed. Its static phase is normal or reverse phase. In positive

Page 81 1358540 V. INSTRUCTIONS (78) The phase of the phase chromatography column will be the polarity of the non-polar phase. The phase of the phase using the phase of the phase is changed, the phase of the phase will be any polarity of the polarity of the polarity. When the complete polarity needs to be changed, the surface polarity is proposed to be flushed to the static phase in the order. That is, the polarity will also be polar, and the polarity will be increased in the composition of the sample. So the separation of ingredients. It will be the component of the south of the column of the additive brand. Most of it is decremented from the same type of tube that is controlled by the governor I. The buffer-dissolving polarity will be flushed into the polar phase in the polarity-selective polar and non-polar sub-columns, resulting in a reverse phase reverse phase static phase liquid and the same phase. The polarity of the chromatographic tube or the positive phase of the positive phase is raised in an ascending order, the fraction will be in the order of reordering, so that the polarity is left, the control needs to be in the column, in the static column Will be controlled by. When or decreasing, the polarity is non-polar or the phase is changed so that the phase is not available to obtain the polarity order and properties to be used in the example of the normal phase column for the reverse phase column. Medium is appropriate, but only needs to be reversed into a reverse phase column. The non-polar molecules will be rushed first, followed by the polar molecules, depending on the polar order of the mobile phase used during the flushing. Therefore, in the current flushing, the flushing of the component is also controlled and operated in the desired mode by controlling the polarity of the phase and changing its order in a sequential manner.

Page 82 1358540 V. INSTRUCTIONS (79) The flushing of most samples is done from a high polarity phase to a low polarity phase. Therefore, the components present in the first zone in this characterization will be inherently highly polar. The same mode is applied to other regions, the medium polarity component is flushed to the medium polarity region (second region) and the low polarity or non-polar component is extracted to the non-polar region (third region). When a positive phase column is used, the pattern will be reversed due to its eluting properties as described above. Most highly polar molecules are chemically and thus will be highly reactive in biological activity. When it enters the first part of the digestive system, it will immediately begin to act on the biological system and the enzyme will appear there. The component then enters the stomach and intestines and undergoes different changes (later absorption, Vipaca in Ajal) due to the digestive juices and enzymes that appear in this part. Molecules with high activity (high polarity) during this absorption will immediately begin to interact with the biological system and demonstrate its efficacy. Compared to the Ayurveda, the intestine part of the human body can be classified into a pita area in which high-polarity molecules play a major role. The institutions caused by heat will play an important role in the parts related to diseases and biological institutions. It indirectly indicates that the molecule is a highly active, highly polar molecule. After this absorption, all of the blood that has absorbed the component will carry it to the heart and the portion that is connected to the heart. The blood will then be delivered to different parts of the body. In Ajal, the higher part of the human body is defined as the card-issuing area, in which cold institutions will play an important role. So the medium-polarity molecule will play an important role in the institutions associated with the area.

Page 83 1358540 V. INSTRUCTIONS (80) The low polarity or non-polar component will only be transported into the body via blood. Therefore, an organ in the human body that can only obtain the chemical component by blood will become the last species of the polarity. The non-polar oils, fats and other such molecules and mechanisms in the human body can be classified as pagoda disorders, and other such disorders can be treated with the same type of material. This low polarity or non-polar component will be flushed to the last region of the feature. Therefore, the area (the third zone) can be regarded as the pagoda zone. Thus the basic body fluid of the molecule can be defined to help to understand what disorder it will act on (in summer) via its polarity. Therefore, the recommended method contributes to the standardization of drug treatment. The image can be divided into three regions on the X and Y axes. The conjugated property (the absorption of radiation of a particular wavelength) has been presented on the Y-axis and the polarity can be present on the X-axis, using the polarity of the mobile phase to control the elution of the component. Now, as reported in the literature, the Y-axis has been equated according to the wavelength (color) according to the effect. The entire image can be divided into six spaces in which the chemical has special conjugate and polar properties. This property is in turn proportional to the component therapy in that space. Therefore, when the characteristics of a drug are identified, the absorption of a particular wavelength and the presence of a particular polarity based on the color appearing, the estimation of all colors in the region and interpretation of the efficacy of the components of the drug. Therefore, standardization of all therapeutic effects and chemical standardization can be accomplished using this method. A summary narrative has been provided in Table 15 to indicate that a drug does not

Page 84 1358540 V. INSTRUCTIONS (81) The relationship between the efficacy of the same component and the coexistence and polarity. The 3_D chromatogram of the drug will be analyzed using all of the three-dimensional properties of the above images. If the 3-D chromatogram can be considered as a 'heads with a headscarf', the entire three-dimensional fit of the hat, there is another sample of different qualitative and quantitative properties, the suitable range will be described as certain and quantitative analysis report. Here the headscarf of the hat is used to compare the absorption peak of the molecule at a particular wavelength. A sample with many numbers would resemble a hat with many headscarves. Therefore, the cooperation of the three-dimensional coordinate axis will provide a very simple comparison and analysis method. This suitable coordinate axis will provide qualitative data and the appropriate range will provide quantitative data for the sample in the study. It is made possible by special software made for the plan. This method becomes a fundamental method of quality control. But any method that lacks quantification will not work. Thus, all colors of the components in the image of a particular region can be considered as a representation of the number of polar components in the drug. Therefore, all of the components appear in the Pita area of the first zone, the second zone of the card-issuing zone, and the components of the third zone of the pagoda zone are presented in the form of a pie chart indicating the efficacy of the drug in each disorder. The proportion of the effect on the. Therefore, a drug having a composition of 5 0 : 2 0 : 30 order will be a drug of the order of 50%: 20%: 3 〇 %. This can be done using the developed software. Therefore, the therapeutic effect can be quantitatively standardized. Increasing or reducing any one or two other summers can be accomplished by formulating the drug to add other drugs and prepare a suitable formula to treat a particular individual.

Page 85 1358540 V. INSTRUCTIONS (82) The standardization of the chemistry can be accomplished by quantifying the individual components by using the software based on the concentration of the component represented by its color. The range of wavelengths absorbed by a molecule represents its conjugate nature. As described in traditional standardized methods, the color of the drug is classified according to its color and efficacy. It can even be applied to any molecule example. The color of Table 8 and its efficacy will explain how color is used for the standardization of a drug's efficacy. The color of the molecule can be understood by the nature of its ultraviolet-visible radiation absorption range. In the color of Table 10 and its relationship to wavelength, the color of the drug and its characteristic wavelength have been provided. Depending on the structure, the functional group, conjugate, and unsaturation will affect the absorption wavelength (maximum absorption) of the molecule. If the conjugate of the molecule is more, the absorption wavelength will be longer. Therefore, the ultraviolet-visible absorption of any molecule can be widely used for the qualitative and quantitative properties of the component. The color of different drugs and their efficacy have been provided in ancient literature. The color of the molecule is due to the special chemical nature of the molecule. The color of the flame has been used for qualitative testing of metals and related products, including the basic spectrophotometric principle. Therefore, the study and understanding of the interaction of electromagnetic radiation will contribute to the study of the chemical nature and efficacy of the drug. The same principle has been applied to the current method of characterization and standardization of spectrophotometers. In other respects, an existing concept has been presented in the form of a novel analytical method to remove artifacts. All in the form of the drug's efficacy

Page 86 1358540 V. INSTRUCTIONS (83) Drugs that have developed identification features are provided in Table 14. Details of the software technology have been provided in the comments posted by the software. Notes on recommended software 1) System requirements (minimum) Information processor: Pentium II II or higher Operating system: Window 95, Window 98, Win NT 4.0 and Linux Random access memory: 64 MB or higher :14"Color Screen (1024 X 768) or higher: Java Development Tool (jdk 1.2. X) II) The operating mechanism of the software can be described as follows: The sequence of operations has different powers. Figure 1 1 5. The title of the eight red ί soft body: rainbow (an image analysis software for the identification of tomography) The wind θ * π ρ of the software, for the identification of the chromatogram and the subtle image

User Interface, a special image for the tomography

# ί 软 软 疋 GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI GUI ^

3. The report is in the form of a chart S

1358540 V. INSTRUCTIONS (84) 4. Life cycle a. Input: Image b. Processing: Analysis includes the extracted color (standard 7 colors and some different chromaticities) Re-made according to a certain size, divided into 20 minutes The three areas are represented by graphs (bar graph and pie chart). The standard basis for bar code selection is: The software uses eight colors, namely red, green, blue, yellow, cyan, magenta and color. . Any color is not absolute. Rather, the shades of the following colors appear before and after mixing, which vary within a range of values. The range of colors used to define the respective values provided by the color has been taken from the internationally standardized 256 gradation. The value used for the current software is: For Red Red Blue Green 20 0 - 2 5 5 0-64 0-64 and 192-200 0-64 0-32

Page 88 1358540 V. Description of invention (85) For green red blue green 0-64 0-48 200-255 0-65 0-64 65-191 For green live blue green 0-96 200-255 0-191 Other colors can be used as a standard for color selection. (These colors are specific to the current software requirements and can be modified as needed.) "^ The point storage image will be merged and imaged, and the color will be sold. The soft quasi-figure is the standard shape, and the color strip is as if the sub-analytic index of the sub-paragraph is in accordance with the image, and the image is converted into a trans-field value area. If the image is like a shadow, the image will be left like a stagnation, X. If the data is stored in the digital display, the data will be transferred from the long-wave data. Produced by Lu 4. The body standard soft IV·-181 seat layer D system 1 3 color code and blue bar profile { wheel B built t and other \ly > to - color value shadow C number, the or 1 change

Page 89 1358540 V. Invention Description (86) Barcode. d. User interaction: Allows the user to interact with the product in a variety of ways. 1. Enter the desired image (one or more) 2. Re-create the image size to the desired size and analyze it. 3. Save the image, resize the image, and graph it. 4. Print the image, resize the image, and graph it. III) Technical Features of the Software 1. The soft body name is 'Rainbow' 2. The software has chromatographic feature images of different formats (range) such as BMP, JPEG, TIF, GIF from its folder. The ability is analyzed in different colors that appear in the image with a single point of view sensitivity. 3. The software has the ability to display the information of the phase point in the form 1. A chart with X (0- (min. time unit) and Y (200-800 nm) coordinates and a pie chart with each The individual values of the absorption peaks automatically or manually are in two separate columns next to the figure. 4. A software has the ability to print data generated after all analyses by using a printed image (PRINTI c ο η ).

Page 90 1358540 V. INSTRUCTIONS (87) 5. The software has the ability to change the page settings of the print by using a PAGE SETUP Icon. 6. The software has the ability to select a partial image and analyze it by using a RESIZE Icon. 7. The software has any number of image analysis windows open for different images and the status is displayed in the WINDOW Icon. 0 8. The software has the ability to distinguish the image into three areas at a distance of 2 minutes. Use the area image (Z0NE Ic〇n). 9. A software has the ability to invert the selected image by using an inverted image (INVERT IC0n). 1. A software has the ability to convert the image into Notepad, Word pad and MS W〇rd by using an EDITOR Icon. In the first place, the body has the ability to characterize various operational information of the software by using an auxiliary image (HELp ic〇n). Silly ^ f has the ability to store the generated data, using the save new image (SAVE AS Ic〇n)' into the *.jpEG file format.

1358540 V. INSTRUCTIONS (88) IV) Installation instructions for the software: a. J ava 1. 2. The installation program of the X software platform (the current software work) detects the Java CD - R Ο Μ Jdkl_2.0/jdkl.2.1/jdkl.2.2 setup icoη double-click this setting will unlock the file and confirm from the user whether to load the software in the system, click on 'Yes' to enter its requirements The path to install the file will be via the implied value. The path c:\ jdk 1. 2 If you want to install it in the "d" slot, change the path and install the software. Once the installation is complete, go back to c: and open the name. Provide the next path for the 'autoexec, bat' file to open aut 〇e X e . B at the autoexec.bat slot and write it down as follows, set path = d:\jdkl.2\bin:% path% setup Class path = d:\jdkl.2\lib\classes. jar;% classpath% restart ii using b _ recommended image analysis software installation 1. copy the image analysis software folder from the CD on the system To the required path.

Page 92 1358540 V. INSTRUCTIONS (89) 2. Exploring the batch of files in the software folder formed in the copied image analysis software. 3. Right click on it and click 'Send to Desktop as a shortcut' 4. A 'MS dos' shortcut button appears on the desktop. Press the right button on the button and enter the properties, select the program tab and check the 'close on exit check box', and convert the window state to minimize 〇 5. Apply and Close. 6. The image analysis software is now ready for use. Press twice on the image analysis button and the software will start working. 7. In the window that opens, a box with 'CSIR' will be opened, where the password 'dvk' needs to be typed. 8. Click the arrow symbol in the lower right corner of the open window to launch the software. 9. Turn on the path for the unconstrained contour image and choose to analyze the image. The image will be displayed on the image window. 1 0. Click on the red analysis window marked with red. A pie chart will follow a chromatogram with a residence time on the X-axis and a nanometer on the Y-axis. 1 1. Select green, yellow and orange for lower concentration components. Other colors are almost at the baseline or lower and can therefore be ignored. 1 2. The details of the other features used in the software have been provided in the software. The auxiliary project list contains various features and applications of the software.

Page 93 1358540 V. INSTRUCTIONS (90) V) Known program errors: No use of v I) abbreviations: JDK: Java development tools C ο η: rim chromatography 3 - D: three-dimensional layer Spectrum W0S: no unit X: indicates the retention time of the chromatogram Υ: indicates the absorption in the 3-D spectrum and the wavelength range R in the wheel waste chromatogram: at a particular image point Red intensity G: Green intensity at a particular image point Β: Blue intensity at a particular image point VII) Meaning of various images (icons) and functions a. Printing images will help print all The data generated after the analysis. b. The page setup image will help to change the settings of the print page. c. Re-evaluating the image will help select a portion of the image and analyze the selected portion of the image. d. The window image will help open any number of image analysis windows and status displays for different images. e. The area image will help to separate the image into two areas at a distance of 20 minutes.

Page 94 1358540 V. INSTRUCTIONS (91) f. Reversing the image will help reverse the selected image. g. Editing the image will help to convert to Notepad, Word padA MS Word ° h. The auxiliary image will help you to learn about the various features of the software operation. i. Saving a new image will help to store the resulting data in a JPEG file format. VIII) Constraint: a) The current software only acts on contour profiles without units. b) The unit on the X-axis is 1 - (belongs to "minute") to represent the residence time of the profile spectrum c) The unit on the Y-axis is 200-800 nm to present the wavelength range that guides the analysis. d) The resulting image must be sized via the image soft weight to match its analysis time and wavelength range on the X and Y axes. e) The image after the analysis will only be stored in JPEG format without unit 〇 f) The image should be stored in the extension of X 4 and the Y 2 and Y 2 of the S. The main advantages of the present invention are: 1 _ drug contour layer cup ^ • and tender u μ i A \ η analysis 4 becomes a feature of the drug. Because the spectrum contains an ultraviolet-visible spectral band with a thickness of 77, which is accompanied by

1358540 V. INSTRUCTIONS (92) The polarity of the molecule. The characterization of an identical drug extracted at different p Η values helps to understand the release of the drug in the intestinal system at different pH values to promote the drug thermodynamics of the study drug. 2. The spectral band of all components can be provided in a single picture to assess the efficacy and nature of the drug, which is very easy. There is a sub-division of S. The sub-division of each sub-element is as follows: one has been singled out, one finger is in the form, and the permutation spectrum is analyzed. g-plasma-D-light 3 has} the extreme length of the sex 3 and the yoke of the yoke heart r& ηβ material to the public levy of the special administration of the medicine to the grass gate to the door to the sea and the national court One method. In the use of the use of more than misleading, and the use of the control of the quality of the 4 medicines in the grass help 5. The database also provides medical evaluation of various medicinal plant areas in the country (by efficacy classification) Information and the role of this ecological factor in the chemical composition of the same plants available in various tropical regions of the country. It may facilitate a medical expert or an herbalist to select a plant for the collection of herbs suitable for the treatment. 6. The use of this software for characterization can provide ecological considerations for different herbs available in the country and can be used for quality control. The courts and customs departments manage the use and misuse of herbs of concern to the country.

Page 96 1358540 V. INSTRUCTIONS (93) 7 • This characterization helps to understand the efficacy of the drug as reported in the ancient literature for physico-chemical properties. 8. The analysis also provides information on the medicinal evaluation of various medicinal plants in the country and the chemical composition of the ecological factors in the various regions available in the country. 9. The characteristics of the treatment and its classification of ethanol-phytochemical characteristics help to bring about some generalizations that can help doctors and researchers analyze the characteristics and have a complete understanding of the traditional medicine. 10. By making the image of the drug/plant extract/plant barcode to avoid plagiarism, the device using the image creates a code via a notebook tool. 11. The barcode can be used in all commercial transactions of modern enterprise resource planning and customer relationship management applications. Efficacy of the Applicability of the Invention Internationally, the present invention facilitates the characterization and patenting of traditional medicines in the country in any country. Because the characteristics of a single medicinal plant will not be related to the same plant in another place or country due to differences in their chemical profiles.

Page 97 1358540 V. INSTRUCTIONS (94) The characteristics are similar. The difference in this chemical profile is due to the influence of this ecological factor such as the difference in its tropics, the soil, the water quality and the chemical differences of the flora and fauna in the plant. This approach helps the country to implement the regulations developed by the World Health Organization and to standardize the methods for the utility and quality management of the drug and its regulations. In the country, the present invention contributes to the prevention of international plagiarism of traditional medicines by virtue of a law developed by a medicinal plant that is characterized by the state's assets. A patent may be objectionable if it applies to any type of patent in various parts of the world, and if the identification feature is in accordance with the characterization of the drug, which is available from the challenge country. In strategy, the barcode design of the identification characteristics of the drug contributes to the reliable management and protection of the medicinal plant. Business and management work is made easier by converting the bar code of the feature into a machine readable language. The drug is characterized by the food and drug manager, the Customs and Central Goods Tax Department, which manages and inspects the use, misuse and theft of the drug within the country, and when such drugs are approved for import. In the industry

Page 98 1358540 V. INSTRUCTIONS (95) A characterization developed for a drug or formulation can help the company protect its process technology by comparing it to the characteristics of the same drug from other brands. Therefore, the present invention helps to enforce its patent regulations more efficiently. This characterization helps to monitor how the drug changes its drug properties by the addition of another drug at different stages of the process of preparing a formulation. The industry can use this library of signatures for all native plants available in the country as a selection of locations for a drug. The database can help the industry, part of the country, and the local season to be suitable for the collection of the herb when the ecological factors change the efficacy of the drug. Scientifically, this method helps researchers understand the formulation of traditional formulations. It also helps monitor new formulations in a formulation. It helps to understand how new molecules are formed when formulating a complex traditional recipe. This feature, developed for the extraction of the same drug at different pH values, helps to understand the release of the drug in the intestinal system at different pH values. The profile chromatogram of the drug becomes a feature of the drug. Because the spectrum contains a concentration with this component, along with the polarity of the molecule, the ultraviolet-visible spectral band. The spectral bands of all components have been provided in a single plot, so it is very easy to assess the efficacy and nature of the drug.

Page 99 1358540 V. INSTRUCTIONS (96) The 3-D chromatogram becomes a photograph of all spectra of all wavelengths of each component in a single picture, indicating the chemistry of the proposed molecule (common and polar) )nature. The database also provides information on the medical assessment of various medicinal plant areas in the country (by efficacy) and the role of this ecological factor in the chemical composition of the same plants available in various tropical regions of the country. It helps a medical professional or an herbalist to select a plant for the collection of herbs suitable for the treatment. The characteristics of this treatment and the classification of ethanol-vegetable features help to bring some generalizations to help doctors and researchers have a holistic understanding of the traditional drug by analyzing the feature. Current methods facilitate the chromatographic characterization of prepared herbs and formulations, and are useful for many quality control and management purposes. Current methods facilitate the chemical standardization (qualitative and quantitative) of the above drugs by providing co- and polar traits of individual molecules in the drug or any organic or organic-metal compound having UV-visible absorption properties. This type of analysis is part of the analysis of most of the herbs used in single and compound herbs, where the use of external or internal standards is virtually impossible. The present invention facilitates research, understanding and monitoring the efficacy of the drugs in the above studies. The present invention helps to understand the role of this treatment and the nature of conventional drugs that have been reported in ancient literature and to identify the same portion in the form of a reproducible analytical data. Accordingly, the present invention provides therapeutic standardization of the study drug. The present invention exhibits polar regions such as polarity in the sample, medium polarity and

Page 100. 1358540 V. INSTRUCTIONS (97) Non-polar molecules help to understand the overall efficacy of the drug. The present invention facilitates the re-standardization of the reported drug to current therapeutic needs. This method helps to monitor and study the formulation of new organic and organic-metal molecules with UV-visible absorption properties during the preparation of a reported or new formulation. It also helps to standardize the process technology of a reported or new formulation by monitoring changes in the composition and its chemical and therapeutic properties. The invention facilitates generating a code by a built-in barcode making software, wherein X is a residence time, Y is a wavelength, R is a red image point, G is a green image point, and B is a blue image point, by current software. The coordinates provided. The present invention can also facilitate the production of one or more of the components appearing in the feature to facilitate the transaction of the business, by enterprise resource accounting and customer relationship management applications. A prepared database can help management to monitor the dynamics of the above drugs from production to consumer inside or outside the country. The thus prepared barcode database becomes a resource for an ERP vending machine or any such <: the machine will display all details of the drug such as the company's chemical characteristics and the efficacy of the drug. The present invention makes the identification of the drug more reliable than before. The use of this method to generate a library of features helps to bring about a generalization of the efficacy of plants of a particular therapeutic class. So, find out why a particular plant is assigned to that species. This reason has been explained in Table 1 4 〇 The characteristics printed on the label of the drug can help the doctor understand the efficacy of the drug before use and confirm the quality control of each batch of the drug.

Page 101 1358540 V. Description of invention (98) Analysis of the same layer of the drug should be fcBl hL·% of its various help) There are decomposed complexes and any developed philosophical images like a single image (contour layer Many uses of the profiling step. In the society, the present invention is directed to a consumer to help him understand that the efficacy of a single or complex drug that has been proposed on the label is the same as determining its inclusion. The present invention can help consumers To monitor the quality control of the market-sold herbal medicines and to protect the interests of consumers. Image analysis of chromatographic characterization images (contoured tomography) of any developed philosophical (single and compound) drugs on the additive, Helps with the determination of any additives in the drug.

Page 102 1358540 V. Description of invention (99) - • zc but 萆-35- --^- & take E bsi: r's ^^"ί>h>ui: 3ss-- 0SS-?>; T二73 25>5·) ^-^--•.系均ϋ- "13·®; !::,asif is 4.ΛΙ.;# κ^^ΐ&-ίΛ-ι-ι- 1..?-ι--νιν-'Jks) •-----gam,-") '-.mK^-Msnlhwi.si3 ^-(Ε--^ϊ ALs3s{NCSI-r£•jt ^stMkhri'^^) 2.-^.^---1-^-=. ,M- •/"s--p-^.-*"- -3⁄4 i· pr per -αΛ-ίί {£- 2,i 3·λ 4.? ys--two>ri >rx$>;lr-£ •ίϊ-ε I Iwawa. /3⁄4) 3.s"--;mi* -- Uiulvml-JL) lu (s;·^-/;"-"(chu, y^, >1-'-(Mry-*- •r-7/iE-<lgr-a- 1. ;K 2. h •Λ昤 and I.SM1. J- •^^(Nccr.^} 3-r(Thcc.^s"-->gl5' 4. -ii(vayu.?) 5. K -il(>kasa. ΰ --5 -5···5 I.-2.- -·- 1.·ϊ-ίΞ,Β;1π11. i-flssll·-) 3.ssr"(sl. -.'") 4"Agricultural^r??u>uldi-ii) I·- 2.c'-3k -.tt 5. Guest 1: s:--?i£ 2-y -Mri=5 3:3sir<nco-} "-s'--vipilkam) 1·ίκδ-;轵-6 -i--'-Jsi--l^J! 20 H-ts&i//5'2 iTs- _3 5..iHas^i'--·"一ιΐϊ- 31-5 -i^-l-1·2 ·ί1·ίϊ 1.^60 2---- 3.S -.-s -'ss^: all 涔.-;.·3'·'-淳- ^-ssi:: 1.-1,3⁄4^iMM2ilhs<Kml.^.Al.ri:-Ns) •^-^namya.-^'"--- ,-/®,Hr-surccha:&amp ;"ss'2=·- 4. •vuitiMMU ii V- iy-.'*sff'g/,vs ) v^s^s^-···.-^- ^s-^Ji-^LcszunsBdull} L.^^^sisN.la.^8·*5^'-'^;.2 Khrg-'Jk^) S(I -&羿(Ts-.sa) 'Kvss·85^.*- 6.3 ^--:11--.-1= '/fcLiKhl-ia.it*-"^) rs^ 2. JkA* 3. Ai a 4.S 5-·- l.&wUKauam3-m>3 '-^-sil-la-N-us--ίν^^^κο/-ιιρρυ--2";" ^--^^l-umbu-klllc) •^^^j^/l—vindhu. Karu, -Net,-屮) |;'>"-·^ 2.";.^ ,ϋι •ss '",is 7'-t?s "ϋ:, Γί-5-3 ^u^r^^--MHJUiJP^l·1-"-^^怠-ψπ-ι-έ^- ♦ I.^-'(I3C5 ^-^(Barai) 3.sAr3(-asccna) it ^^'ri Ma> l.^s-yae 2-soci-l) 砝-一淤朵辛-* ι·&-2;1 a) a-s<2utram) •-ts'iiuvcrv-' ) 1-^.5.0==--1-2. ;M-£2utra) sus\vcda) ^片^-老Π-Μ>·Λ- lllllll Page 103 1358540 V. Invention Description (100) y N Rz (a - O factory

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R^0 2. nrjttr;3. st4. siis 5. ^53⁄46. ^-5 i->juiL s- (s-adruch-s) akJr^s.JiL b.£p c.-lss d_-£ ZHJily: 2^-^-:^^^-^ ^3s l./uf zinc buckle (vaishcshik) •-^^{sanlanya) •^-^i&ns) :£·啦薄淬 as^=: _ϋ (5) ^卟(^®) 纹听泫(渰s) sAL#ii (抻舞艺,斿2s,抻垚s)珐AIL (-s) ^ Is- 3(;-s) 3.-3铎-2 4 .-I*--•^-liL-^i'iuts a. ?+mis b. K-AL(>glli)+ ? c. ^^clala) 十St- ALdk+舆fjtb+is.圉茧ss- (ΜΑ—υτΛ RELATIONS WITH DHATUS) a. ^^-^实贫b. -农容- d.-t-^^^ c"--5"^^- ^ f &-itBsiyi琀a. '^i-iLb. ^4p c.^^3-13-*·,5^^^ckJ^A-iL d.+sc^J^^-i-'^s. c+ letter ".刼农,卟卟-钤扣均Γ.+函砮吟^SIS55 # --s+ (vipaka)s =--3-An 3 quenching) Painting·· 104th page 1358540 V. Invention description (101) -t - UJ to one SINo. 睁h- Element-Η α β Receptor bladder detachment! ss ώ 胆 腹 (Pus) Kidney lung spleen heart liver (Tsangs) fear c; w happy angry emotion skeleton _μ__ muscle vascular脉衣,二* *«* -&* QH- miscellaneous steam 4 〇 ping ο·知萃4:^孩畀厗扣+函比-fe-e-st,*r唞玢尹黟艺网今格萃£>ii!£t!Mt~sipl-> cooking t-Λ UJ Ο SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI SI ι ι ι ι ι ι ι ι ι ι ra ra ra ra ra ra ra ra ra ra ra ra ra ra ra ra ra ra ra ra ra 芩 芩 芩 芩 芩 芩 芩 芩 芩Description of the invention (102) Wife m's sexuality 1 Definite disease (3 Disorders of ugly ugliness, harmful cold, tidal night, bright 旸 (hillside 60 dark side) Husband | Good male | Negative | P7 beautiful and beneficial it> dry © dark yin (bright side of the hillside) 馋 6 6: iu&^it^-c-匦輮aluminous f 靼13⁄4 S t-铋\〇'j on UJ h· Bu h· W 令«Λ *Λ OU ίν i χ>ς> CS G^ 睁h· upgrade element 〇OC 〇\ to as> Cffr as> Crrr 1φ 1Φ •Λ «-Λ4 c>C>> 昤m Element £=>£=> ffi^T π>π>Π>Π>0> C^' Μ* Ling S m C: Ϊ Μ η P? ?? S3 > + a 知莩 S: Knowing the choice of iluL-6·輮輮倍渰^'_53艺芸尜涔拉盆芽芽

Page 106 1358540 V. INSTRUCTIONS (103) 枓嗥淞 s&+>^诤1!0-耷私-+ 1 The name of the animal/material 33⁄4 in the name of Sanctuary (Name in Sancrit ) -1色-1 Sueha Cliuna (Lime) Kak eats Priscilla (Kaclihapa Prisla, also shell) Cyclone Ha (Slumkha, Conch) Shankti (Shukti, pearl-like) Varati Card (Varatika, small shell) Bruce Xun ^ (13rushtashma, grayed stone) Satan Kara (^rkara, sugar) * Nagaki roots through the mountain Vijayantu by Vaidya Narahari Lltf From Shukla Varga White 铯物古森跋蒲彡 Mpa (KusimibaPuslipa) 佥 Suka (Bimca Monosperma) (Kimshuka, Bulca monosperma) Harry Della (Longdra) (Maridra, Curcuma longa) Patanga (Caesalpinia sappan) (MaeJayantika, Lasonia Incrmis) * Pull Rasarnava 丄ii m It Pccta Varga Yellow scorpion Dharma (Puni Karnateng) (Dadima, Punic a granatum) Palasha, Butca monosperma (Laksha, Laccifcra lacca) Bandhuka (Hardud) (Kiarumra, Curcuma longa) (Kusumba Pushpa) ttSita (Manbiasta, Rubia cordifolia) *Kajanighamu GhiVCTtiv q$ Rakta varga Red drug card Kadali, Musa paradisiaca (Karavcllika, Momordia charantia) Terry Fara ( (Triphala, Three myribalans) (Ncclika, Indigofcra Tinctoria) (Ncclika, Indigofcra Tinctoria) Nala (Nippon Bosphorus) Cymbophogan species) Panka, Lolus Kaseesa (Fc2Sj) Barrama (Unripen Mango) *Rasendra Cluidamani Guide mi free! IL 纳 invention (Krishna Varga) — Ο.-—-- black mother 11 round __11

Page 107 1358540 V. Description of invention (104) Treasures containing enamel and brazing (?-Art Xue bud Benz Ben 3莩121-:;; 1 for &0>'诤. MT^piHirisv^ 2. 癖11 is - 3. Net 莽 -irri · 5. ΪΓΪ-6. 3⁄4% - ooMiiL - 9.S2H1& - 0. sss^- 1. ^Isochrome - 2. Raspberry-«-|二十一众- 4.莽Φ -|> 钤 舶 f f 1. -ri'ssse 2. ^is.3=vJk 陶 3. ^-/1 ssg 4.3?-^ 5kutis ¢ 3 6.s^ l.-&sst .a% 43⁄43⁄4 5.?H./S- 6.S 7.弇#垆荔oo.lva^^- 1.3⁄4•苕Fi? ^β -2.S 3.f»iA 4.1^23⁄4 5. Mail m 1 .EN-Tsis' 2.& soap 60 potential and · 3.萆孬60 hot 袅 - 4.irr·'*. 5. Ί..Β - 6. 丄〇-12-0 ;衮7. Very difficult> Axe 6011^ 8.41MS - o.if/Nl-^f - 1. Body 6〇iilHCT 爿π 2. 萆S-2-孬Ilie 3. #,fu3rrJ 4. -&amp ;^4*ίφί' 1. Ma Zi 2.S 3. 瘁 4a; il 5. 3⁄43⁄4. 6. E-5 7.SSJ泠8.Τ.ΒΨΪΨΪ [Β>夺·ύ>'. η 耷C5&gt Lang choose-C ο* 茚ο Poor # _关第108页1358540 V. Invention description (105) 枓亩> Tea 垚 畀 聆 聆 聆 聆 聆 会 会 洚溆 洚溆 洚溆 ow ow ow ow ow ow ow ow ow 卡 卡 卡 卡 卡Asia) Bitter (Ticka) Building (Calgu) Lavalna) Acid (Allah) Correction (Ma Deming, Miidluii·) 1 + V·· + · + + $ + + The main element of the 伐塔ΐ Pita and Kafa 4· 伐塔ΐ Pita and Kafa 丄Pita with 塔塔t 卡发i Pita and Kafa ΐ 1 丄 丄 丄 与 与 卡 卡 卡 卡 4 卡 卡 卡 卡 卡 卡 卡 卡 卡 卡 卡 卡 卡 卡 卡 卡 卡 卡 卡 在 在 在 在 在 在 在 在 在 在 在 在 在 在 在 在 在 在 在 A A A A A A A A A ), pepper, red bell pepper, dried Ginger (Zinger) 陲 望 ,, 脱 脱 milk, squid milk, raw mango 荔 dad tg win ^ ίρ - card full J ^ S 9- diet items | fa- r Temii丨ialia chcbula, Trcminalia Bcllcrica, pearl, coral Azadiracta indica, Stytia yaleta Svverlia cliiraita), Tinospora Cordifolin Piper longum Embalika oiTicinalis Gry.3⁄4海扎拉拉拉 (Glyccrrhiza Glabra), Asparagus Raccmoscs, gold > 赛 ^ 畀轵 畀轵 畀轵 捽 捽 捽 捽 捽 捽 弈 弈 弈 弈 弈 弈 弈 弈 弈 弈 弈 弈 弈 弈 弈 弈) Off the insult Qi smelt 33: offend all dressed leather total cen

_1_画第109页1358540 V. Invention description (106) Zifuwei translation of the bud;|2|;1 preparation 12-^60笤@苒因私^^3~-1:.^丨$莽笤| !1&0洚芹^知-%&&0苕^. >780 650-780 595-650 580-595 560-580 500-560 490-560 | 480-490 435-480 380-435 <380 Wavelength nm Near Infrared Red Twilight Yellow Yellow Green Green Blue Green Green Blue Basket color purple UV color (absorbed from white light) Blue green green blue blue purple purple red red color color yellow green toe color (transmitted) or complementary color * s s.. IBii

Page 110 1358540 V. Description of invention (107) Net " Dilution buffer (: 02 excretion H4 absorption CPS abk -^It"- Λ -"cps-^ -=1"--〇60洚- -- UILS-Hua acid scorpion venom normal base + poison death page 111 1358540

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Description of the invention ([TMT 5 preparation Jss^s-^iu-saiL^iHrro-PLC) ^sn^^^-r 射萍择^iuap^^s-lpLC) atBiuifL^^-ri. quenching, β) P-^s-5 l"ss-iilh>--E-涔詗. 2. ^3^^^^--^ 兹-'-衮埘妄昤fe--vr7-s 今-r 3. - ;n3-D^ar--> lt--^^^s^^r- ^ββ 4-ϋκίΓ, ~·ρ l.lsfs^铤ϋ-^^-ί/;-si-buxit笛菡.Ηι-Β60··'>+ •33". ;*哞8^,7-^^ Cave 200,800 1^ES^--iuuo 洚-·^^;?; 呤 一一^帘孟斧绔 绔 soft 洚 ^ 3- ^ 5 ^ +. •^^^sl®"1--'5*3芘芽^^^^^'''"so-iJUSJirNtuwHO5 ^-· 5. s^T^^ill-s Luo $t-&- a stupid &""" 珀* •^-:-丨- 异-洛铱荽忘铒-Θ 糸ii ("塔弈s^^^s — jmils 粦薛弈3琴筘朵猝£岧- · l.ii-sa>铎2-"涔涔兹绞4n s宇"a if 筘ai> ^^ti-gls^-f -.3⁄4 · •-3--.^^. •-衾卜-坊汸芦-.s but · 2,-3;-£we----Jls-tHi" ~Do not 刼5烟邰?:功(荈卡丨丨.^ iut^^^'-'- If^ifM2 •^^s---ii 烟片-^保三呙81-?,/,- -iui vh-rl-:lw 1 .s^3-tss 4^--33⁄4 and bucket--£ /i^s忠/rp^Ar -3 •-Fan-Wen-Lengyi泠3丨饮-奔薛妗妗-呦交琪呤今驽-S bag fresh furnace^因今窆^乂涔Y宫_L · • This stupid smoke 5 drink-s: 0 奔-^-^^^-g-/iKSJPEG-^--"^^-^^t-/A^^sid-f&ls. 4 .铋- 冶汶-琛琛踣; Palace--X1=Y2 - 葜 葜. 浼旮^34α-&Λυ Ait> S mixed with enemy-^孑萁-translation. ~科相拉"»刼功- Today's bed sweet palace 泠古诔51--- s^ island film - smoke s-JU£"^4u/M5-?,)^ •^^όο^ϋ-gong3.射^5#; --功•--吕-^年冷竺》^ 3 .^4钤00-烟薛-抑&筇^冷-"士-'和斿>汶榷•妗相私芪s^fN-v^^^iiua^^tr^--fe^-^ 5.刼^60夯-- ut-p-iilL ^^'i-^ •爿^岭5^ Ready to dissolve 异-Different ^Art Today Dart 3. 爿4ws-iilB-^&棼免'·'-"--'-'^^卜迕45 4. 矜相拉芪效^坤芑令笨穿甜^斧-铋玄-'-·-"^-^^ -涔&'^孕烟齐 SS >--^lu Zhou Yi-? ';rs. si Page 112 1358540 V. Description of the invention (109) Table 13: Parameter drawing for the development of the characteristics of the drug. Number of the plant's botanical name. Part of the 3-D parameter used by the common name of the plant. Rotation degree 29 ABEL MOSCHUS MOSCHATUS MEDICUM KASTURJ BENDA Whole plant 20 15 30 Hedgehog (ACACIA SUMA) SWETHAKHADIRA Bark 15 65 31 Indian 戗笕 ( ACALYPHA INDICA) Kuppinta (KUPPINTA) Young leaves 10 60 32 ADHATODA VASAKA Vasa (VASA) Leaves 25 45 33 ADIANTUM CAUDATUM MAYURASHIKHI Leaves 20 40 34 Smelly Pile Fine 包 包 (AILANTHUS EXCELSA) 艾拉卢 (ARALU) Stem Bark 10 65 35 ACORUS CALAMUS VACHA Underground stem 10 130 36 Allium PORUM MAHALASUNA Larsen (LASS ΑΝ). 单独 Individual bulbs 20 130 37 Garlic (ALLIUM SATIVAM) LASUNA 'Lasen, small bulb 20 130 38 South Ginger (ALPINIA GALANGA) Large Ginger plant (GREATER GALANGA) Underground stem 20 75 39 South Ginger (ALPINIA OFFIdNARUM) Smaller Zingiberaceae (LESSER GALANGA) Underground stem 15 75 40 Apricot (ALPrNIA SPECIOSA) Lighter Ginger plant (LIGHTER GALANGA) Underground stem 10 60 41 Areca (ARECA CATECHU) BEETLE NUT Unprocessed fruit, nut 15 40 42 Leaf fruit processed 15 40 43 ARECA KATEEH RAKTHA KHADIRA Fruit nut bark 15 65 Η Page 113 1358540 44 Arnica Arnica whole plant 10 55 45 BACOPA MONNIERI BRAHMI Whole plant 15 45 46 BERBERIS ARISTATA DARUHARIDRA Root bark 15 170 47 Berhaivi Yadi Fusa (BO RRHIEVIA DIFFUSA) PRNANARNAVA Whole plant 15 55 48 CAPSCICUM ANNUM L Mohi (MIRCH) Large, peeling fruit. 10 70 49 Fan Moqi big, unpeeled Open fruit 10 70 50 Bell pepper Mochi small * Unstripped fruit 10 70 51 Cousin Nirvana FENESTRATIUM LATA DARVI I skin 15 125 52 buckle West COCCINIDIUM GRANDIS DONDA Roots and Leaves 25 30 53 Bamboo Grass (Upright) DACTLYLACTINIUM AEGYPTIUM (ERECT) GRASS Leaves 25 40 54 Bamboo Grass (匐匐的(PROSTRATE) Glas leaves 25 40 55 Dristachis CINERARIA TUMMA Leaves and bark 20 15 56 Inbarrica Ou Fahinaris Amarama (AMALAKI) Fruit Exocarp 5 50 57 Beauty Cleansing Cream (FACE PACK) Trademark 1 Formula 20 25 58 Beauty Cleansing Cream Trademark 2 Formulation 20 25 59 Glycyr HZRA GLABRA Yasiti Madhu (YASHTI MADHU) Roots 15 130 60 Grischenya Graber Yasiti Madhu powder 15 130 61 GYMNEMA SYLVESTRAE PODAPATRI Whole plant 25 15 62 HOLLERONA ANTIDYSENTRICA ) KUTAJA Stem skin 10 60 Figure _ hidden 1 Page 114 1358540 63 INNULA RECEMOSA PUSHKARAMUL A Root 5 45 64 MICHELLIA CHAMPAKA MANU SAMPENGA a*·化20 40 65 MORINGA OLIFERA MUNAGA leaves 25 40 66 MYRICA CEREFERA Laurel berry (BAY BERRY) Fruits and seeds 20 35 67. NAHAI All-in-one (NAHI) Whole plant 10 130 68 Wood butterfly (OROXYLUM INDICUM) SYONAKA Stem skin 10 170 69 OCIMUM SANCTUM Ramatuura (RAMA TULASI) Leaves 15 130 70 PLUCHEA LANCEOLATA PATRA RASNA Leaves 10 65 71 PICRORRHIZA KURROH KATUKI ROHINI Stem 15 125 72 PER ( (PIPER BEETLE) 荖 leaf (BEETLE) Leaf 25 160 73 PSORALIA CORILIFOLIA BAKUCHI Seed 25 60 74 Large dish (RAPHANUS SATIVUS) Mulanji, white (MULLANGI, WHITE) Leaves 15 25 75 ϋ RICINUS CUMMUNIS ERANDA MULA Root 10 135 76 'RUBIA CORDIFOLIA MANJISTA Stem, root 10 40 77 SAUSSREA LAPPA Bitter Tree Tower (KUSHTA) Root 5 80 78 SPHERANTHUS INDICUS MUNDI Whole plant 15 70 111 Page 115 1358540 V. INSTRUCTIONS (112) 79 信普罹库斯拉希莫瑟斯SYMPLOCUS RACEMOSUS) LODHRA Bark 15 65 80 TERMiNALIA CHEBULA HARITAKI Fruit 10 40 81 TERMiNALIA BELLERICA VIBHITAKI Fruit 20 35 82 Fenugreek (TRIGONELLA FAENUM G.) 曼HI (MENTHI) whole plant 15 160 83 蒺 ( (TRIBULUS TERRESTRIAS) 钩 徐拉 (GOSHURA) stem and root 25 45 84 Tylophhora ASTHMATICA leaves 10 65 85 pod fans (VIBURN UM) Drugs with similar sources of dyes 20 15 86 WITHINIA SOMNIFERA ASWAGANDHA Root 5 50 87 ZINZIBER OFFIONAUS Sun Ti ( SHUNTI) Processed Ginger, underground stem 15 130 88 Emerpata Karajerna Ayou® Weida Formula Powder 25 60 89 KamaduGA Sidha Formula Powder 10 25 90 Kumaraasa Ajurda Pharmaceutical Liquid 10 35 91 Maharac Mustavilis Sidha Formula Powder 20 35 92 Suvarna Ugraga Gulu Lusedha Formula Powder 10 40 wavelength range, All other parameters of the magnitude of the absorption and the residence time are shown in the individual enthalpy. Painting_1关第116页1358540 V. Invention description (113) 0^ Miscellaneous ^ fr 抅 a» m SS =t private shovel A §1*3 ^ 1W $ ^ < a» > 7S >.淤>泠2S σ η > KUMARAYASAVA Kama reading each 3 r~ ^ > HS % ^ > κ hole old 1 o S Ο ς«* 2寐= dad Annander ANANDABHAIRAVI Indian shovel 1 Ai Mopata Karajal The botanical name of the plant Herbaceous ruptures Ashioka (ASHOICA) Fermentation process Έ 3Λ Philippine Blue PHYLLANTHUS URINARIA Herb HIZRBOMINERAL HARITA MANJARI A common name for a formula plant of Ayou Μ 达 % gynecological diseases gynecological diseases, yellow sputum peptic ulcer yellow - should be sick liver disease, skin wide Disease 3. ^- laxative, peptic ulcer, 痔疥4- <- <r- <r~ <- <- <- Ducha Hera (confidence on it) cF&gt ; Xue 4 whole plant herb ρ 邾屮 part of the use ♦

II1I11I Page 117 1358540 V. Invention description (114) --^^^^- ^si (Hmlsnus AIBIEr MOS.1US) -13⁄4 (CHOPACH1NYAD1 OHURMAM) =&".&^恝 malaria neck enough >D1OD>v>SIn>)

Stsrt04i,i-A*fs>s (ASPARAGUS ADlmSOElzDlE'zTUM) Α·--υ-- (LATA ICASTi) .^s J,i>s 63⁄4 士丨画-钵(KATUVEER.A) 专-^斗^ Food ^^钵弈澄s (SAFE) MUSArl) si蝌 is the key y; 5 slightly poor ^^ {-hcsllma roga, pricha), &^癖=, when"^澄(panduroga, _Rasayalla) " Negative, -"- ---热袅^Jfp #r^i1t (swwsa)

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圆··I Page 118 1358540 Explain the hair, five *R £3} Berri Hatvata Talmani + Svarnamark Skankan (URIIIATVATACHINTAMAN) + SWAUNAMAKSHKAM) 7^ 銶 (VDI1V1A1VH1SV VnOHdOlAl) 〇• Χΐ. •ψν特> 7P P-S &Punnarnava (PUNARNAVA) £ buds fr S η έ 銶 &% >c> Ai Wei Dewei Xu (AJADWBSHI) c> I a> s , , Mocha, white (MULKA, WHITE) Μ >a> I m ·§ί =3⁄4 with Γώ % S 孬 s 揉 揉 揉 Μ Μ Disorders), ncut-racculicals Φ into 4AA. + production 1 耔耷>«. v?-lr» — <- <- <- <- <- &lt ;r~ <- — <- <- <r- 莽M jet Ά lei w. ~A vi^kr,r 屮Stuffing sj* a> 3Ε(* 屮\lAk 屮 %

1丨丽__匪第119页1358540 V. Invention description (116) (C1TRULLUSnolbsYNTms) ^猝, mp^^s (AZAR1D1CTA IND1CA) 3⁄43⁄4 ίπ&·£ίί1σ> s (ΛΟΛ01Λ OATECHU) (V>T> GAJANKUSA RAS) ^JLS^ii-isri-ii-ai-ct· , 1^||0! 锌 § (SHISi) ^ΙιΗ1ϊίϊ42!ρ·ΛΟ α& ^♦ and 耷^ mold buckle 驽 (R1QNUS 0OMMUZ1S) ^热&殍Zn^. {i.l>Y〇G>RAJ> GUGGUlr-u) St. Zhang itching and euthasaza)

Bi^itK.^从.(INDRAVApoi) {N1MB>^^>4丨(KRAMUKA) ^料^^^^隹(RA- Kl.lll> Μ·£ί ^^•ss# ^ί si^ ulRiii&gt ;钵(ER>ZD> MCrA) s4$^i 耷 88&single ερ &.ISP, salary^p, 13⁄4.3⁄43⁄4

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J 1358540 V. INSTRUCTIONS INSTRUCTIONS (117) Solaria de Liferia | Houlerona Antiche Sentrika I Houlerona Antiche Sentrika Rose | (EUGENIA JAMBOLONA 1 SIZYG1UMCUMINI) Bamboo grass (匍匐 and erect) 桫金扣西规恩芬尼斯特拉蒂恩金金锻金(CURCUMA LONGA) 巴庠其由古斯塔库路加库塔加布 (JAMBU) 禾Undergraduate Plant (GRASS) j Harry Della! (HARIDRA) 1 Latadarvi.. 淖 姜黄白病, Dermatological skin disease White J&L disease blood purifier abdominal cramps, all government-sponsored diseases i Abdominal temperature, vomiting, diabetes, dysentery and diuresis Agent, improve skin tone S (3⁄4 5 ^ ^ diabetes, obesity, skin disease - ±浒i浐(J 23⁄4 4- <r- <- <- <- <- <- <- < - <- <- — <- — <- species +, scorpion oil stem, root · ρ poetry; ί> blood S # taken from the stem of ANDHItA PREADESH Peel fruit 丨 whole plant leaves · raw underground stem 1_:_:_ :S. -^ UJ Commercial powder-2 Commercial powder-1 _ 继汇1 Page 121 1358540 V. Invention description (118) Card发 塔 塔 赫 i i i i i i i i i i i i i i i i i i i i i i i i i i i i i i i i i i NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA ) SIGRU (CHAMPAKA) Formula Kumali (KUMAR1) Vacha Dream Dillondra (LODHRA) Mansika (METHIKA) card round its enemy Henika Kas, Vassar, digestive system diseases, abscesses, water and limb cosmetics, skin diseases, indigestion, skin diseases, gynecological diseases, liver cancer (hepatomegaly), spleen cancer (splccno megalyX burns, uterus disease gas 1 s)| answer A CB & Yi Yi I |· Private "3* 3·· Ping Pong | Out of the disease, stocks full, dysentery sugar disease, acute abdominal pain laxative liver disease -> -> <- 4- <- <- &lt ;-- <- <- <- <- <- <- <- <- <Γ- 4- From the leaves of Anda Pradesh The juice of the leaves, the whole stem, the whole plant, the herb, the bark, the whole plant, and the herb. 筠 1_画1111 第.122 页1358540 V. Invention description (119) KANCHANARA GUGGULU 茵妮扣斯坦妮玛ENICOSTEMMA AXILLAE DICROSTACI-IYS CINERA ψ Annan De Bohai Lavi Acacia Syma Herb Formula 1 1 Nahai Villatalu, Guma ( VE12RATARU, TUMMA) Brami Herb Minerals Swede Cadillac Inflammatory Disease Malaria Heli Hiidya, Obesity Medhaia, Skin Disease Pramaha<-<r~<- <--><-<r~<r-<- Formulation Herbaceous plant m and bark whole plant herb formula

^ S 1 桊洛拉拉艾斯马提卡特里卡圆秋纳GH-3 (TRIKATU CIIUKNA GH-3) 特里卡圆秋纳 SP-2 (TRIKATU CHURNA SP-2) Trika 圃chuna - 1 (TRIKATU CHURNA-1) Formulation of Acacia de Nubola Xula single wood formula of eucalyptus 萆 的 纳 纳 纳 纳 纳 纳 纳 纳 纳 , , , , , , , , , , , , , , , • • • • • • • • • • • • Bad Caesar, Swassa, Digestive Diseases -> <- <- <- 4r- — <- — — <- — I» Γ4 5J肆屮$ llllill Page 123 1358540 V. DESCRIPTION OF THE INVENTION (120), J';®.(0N10NSM>F) >»-«·-£3;.οΝ10Ν BIG) -ι:—®φ^ϋ 拉鸯 (KARPURAD1 RAS)

Ets:^^殍JM^^SS (E2BLo> OFF) CINALls) (ocnnUUGo ORnHlolDES) es:^呤&耷(ASPARAGUS ABSOENDEZSPS) Dad;#衣拉-s-hsNongla 3: Unloading®ϋ/5 (PALANDU) 姑>60 buds dedicated to sr (HAEMORRHOID_^_ (ΑΜΑΓ-ΛΚ1) KALI 2CSAL1 makeup cold 筘ίιΜρ·(icl.l, KATIVEERA) sstv.-'> itch array (SWETHA MUSAU ) ±5S, ^. Hanging eggplant, 蛘^13⁄43⁄4 % β, Μ a-airfrw, 蛑^防签^4-22:-|-杂40鸯

Ji$rK-i,ss^-3rr Wood Butterfly, ϋOnaka edema Digestive diseases 4- 4-

S 83⁄4 se.^· 亩圆_ϋ Page 124 1358540 V. Description of invention (121) Similar drug additives waxy mahogany. Wax scented mahogany jinjinping this shampoo powder (13) extract shampoo powder ( G) Beauty Cleansing Bones 3) Beauty Skin Cream (G) WITHINIAPUB. Dye Source Laurel Dried Nuts Laurel Dried Nuts Aesva Ganda Red Plant Roots (ASWAGANDHA RED SEEDS PLANT ROOT) Gynecological diseases The protection of the liver The protection of the liver after the effects of the injury relieves the pain of the miscellaneous to the hair agent. No foaming agent is found to lack some important ingredients such as the scorpion scorpion (sedria) (kushta) (sausscrea) Lappa) and the genus genus (such as jibia) (rubia cordifolia), causing the 66-party, the utility of the poor general effect, rejuvenation <- similar drugs similar Pigment Source Trademark-2 Similar Pigment Source Trademark-1 Similar Pigment Sources S own Formula Formulations 7=

Page 125 1358540 V. INSTRUCTIONS (122) Isolated compound needle cone cone 薜 Diabetic herbaceous material 1 AZAMALYCIN oyster sleeve (VITEXNEGUNDO) 1 .. separated standard compound [single Compound single compound i Pramanha 1 Liver protection 1_ Berberine standard (Froca) BERBARIN STD (Γ1ΛΙΚΛ) The 4& compound (ALLOPATHIC AMIDE) component of a diuretic anti-therapeutic therapy is isolated separately The compound is yellow-like (Λ FLAV0N01D) mh (7-HYDR0XY QUERCETIN) 11111 Page 126 1358540 V. Description of invention (123) Table 15: The name of the drug is indicated by the characterization of the sample. Therapeutic Drugs 圊109 Vitamin-B Group Commercial Trademark Analgin Commercial Trademark Atenolol Commercial Trademark Bromoflexin Commercial Trademark Citerizine Commercial Trademark Furazoli^ine commercial trademark Isoprofen-Paracetamol Logo for Paracetamol Commercial Samples for Herbal Cosmetics Figure 110 Beauty Cleansing Cream (Effective) Commercial Trademark Beauty Cleansing Cream (Efficacy) Commercial Trademark Shampoo (Lack of efficacy) ) Commercial trademark shampoo (full-featured) Commercial trademark herbal formula 圊 111 Agnie Dondina commercial trademark Anandre Bohai Lava commercial trademark Arogyavardhani Commercial trademark cypress Rihart Watatar Tamani Mani + Svarnamark Sukkan Commercial Trademark Qiu Pachin Yadi butan commercial trademark commercial turmeric trademark 1 commercial trademark commercial base yellow trademark 2 commercial trademark commercial a yellow Trademark 3 Commercial Trademark Lake Lucerne Commercial Trademark Similar Drugs Figure 112 Arnica Dye Source Calendula Dyes Source Carolusus (Colosynthis) Diffuse Source Separation Drugs @ 113 栎 精分分磅 from Vitex flavonoids Dixamethasone, Weimeng Ai Mamarisin, Weimei mm, page 127, 1358540 V. Invention Description (124) Single Drug 圊114 Aloe Vera Leaf Indian Paper 苋 Leaves Inbarrica Ou Fahinaris Fruit Aila Luk Bark Betel Seeds Esva Ganda Red Fruit Roots Eswa Ganda White Fruit Roots 之 之 安Laplacian leaves with clasps (Culcutta) leaves clasped with heathine (Coscinium) stems of bamboo grass (erect) leaves of bamboo grass (匍匐) leaves up to Luhari de la stalk Harid Laguna's underground stems, Kalagamun, fruit onion bulbs, kutaga, bark, scorpion, scorpion, sauerkraut, Raktakhadira, heartwood, Xu Laji, special processing of evil green source 1 Xu Laji special processing S Qing source 2 Lajit leaves Φ

Page 128 1358540 V. Inventions (125) 泠 泠 & Pregnancy - ^ 拃洚 拃洚 拃洚 凇 凇 !! A dock.岭兹,, > 屮s^赏.f±琦泠狯畀^ 洚 办 办 冷 冷 冷 冷 冷 冷 冷 冷 冷 冷 冷 冷 冷 冷 冷 冷 冷 冷 冷 冷 冷0 芦和奋£码谇+苏许今莩> Zinc will be Nie-邙-& .6-IS-s»/^P 烟+3⁄4萍佘^12>-Art every 泠.槔嗒洚今 S 3ΜΠ·弈托旮ίιε·Quenching s#rvsiv/ia> S 烊 I-it 洚 tCT±c-o 蚱岑-爿扣洚·Itis 5?. »τ ^--Jls^^'s-"^-) -"-菡详~择系泞/f. 20 40 60 S 1^^^ ί —MrHILP $ir· - 2: 5i-ip 1 ! Pita-Vata Pitta-Cafapita〇>, 1 -V ^'rk owed 00 nm ^or-p 600 i -tp --) um S0 200 i ☆ - Broken till Page 129 1358540 BRIEF DESCRIPTION OF THE DRAWINGS The following examples are provided by way of illustration and should not be construed as limiting the scope of the invention. I. Form 1. The table states the different philosophies and various specific terms used in different medicines. 2. The table states the relationship between body fluid properties and different parts of the human body. - Ajal's method 3. Table stated in Chinese medicine The distinction between the big universe and the universe 4. The table states the distinction between small universes in Chinese medicine. 5. The table states the relationship between five natural elements and their related objects. The table states the meaning of yin and yang in Chinese medicine. The table states the color of the medical efficacy classification according to the table 8. The effect of different colors on different diseases is stated in the table. 9. The table states the nature of the six flavors (the ruthenium in Ajal, and their properties and effects). The table states the correlation between color and wavelength. 1 1. The table states the role of acidity and alkalinity in the human body. 1. 2. Table states the comparison of different analytical techniques used for characterization and chemical standardization. 1. Table statement for the characteristics of the drug. Parameters for development 1 4. The table states the classification of the efficacy of the drug in the proposed invention. 15. The table showing the drug in short text 1 6. The table states that the feature is based on the conjugate Polarity differentiation

Page 130 1358540 Brief description of the diagram I I . Figure 1 A and B illustrate the five basic elements of Chinese medicine and their relationship. Any imbalance of one element (excess or lack) can cause the other elements to be disturbed and become the root cause of a disease. Human health is achieved by managing and controlling the above-mentioned elements of medical order in China. Figure 2 illustrates the effect of color on the basic body fluids in order to damage the associated body fluids by selecting the same color of the drug. The color of a drug is caused by the chemical nature of the ingredients therein, and thus the chemical nature is indirectly used in the standardization of treatment. Figure 3 illustrates the characteristics of the two different trademarks. The chemical profile in this feature shows that the efficacy is due to the presence of more molecules with sufficient conjugation properties. The chemical profile varies with the age of the sample, which is consumed in the soil, and the older the sample, the more effective it may be and may vary depending on where it is collected and the purification process. Figure 4 illustrates the existing use of feature chromatography on a label. Figure 5 illustrates the commercial color chromatogram of turmeric (food). Figure 6 illustrates the color chromatogram of Furazolidine. A color chromatogram of the Krimikutara Ras (formula) is presented in Figure 8 to illustrate the color chromatogram of Xu Lai Te (good in terms of efficacy)

Page 131 1358540 Schematic description of the figure Figure 9 illustrates the color chromatogram of Xu Lai Te (inferior in terms of efficacy) Figure 10 shows the color chromatogram of Suryavarti (recipe) 1 1 statement Color Chromatogram of Tea (Food) Figure 12 states that the color chromatogram of Trikatu (Formula) states the characteristics of all yellow drugs. In this case, Sandiddha Dravyas (a controversial drug) stated a distinct difference, making the identification easier. Figure 14 illustrates the characteristics of all drugs in Pittala in nature. The ingredients appearing in the first zone indicate the efficacy of the drug. Figure 15 illustrates the characteristics of all drugs in nature of Kapela. The ingredients appearing in the second zone indicate the efficacy of the drug. Figure 16 illustrates the characteristics of all drugs in nature of katahla. The appearance in the third zone indicates the efficacy of the drug. Figure 17 illustrates the nature of all the drugs in Pitakafa Hera. The ingredients appearing in the first zone and the second zone indicate the efficacy of the drug. Figure 18 illustrates the nature of all drugs in the card. The ingredients appearing in the second and third zones indicate the efficacy of the drug. Figure 19 illustrates the nature of all drugs in Pittavatahra in nature. The ingredients appearing in the first and third zones indicate the efficacy of the drug. Figure 20 illustrates the characteristics of all drugs that promote Idishahira in nature. The ingredients appearing in all two regions indicate the efficacy of the drug. Figure 2 1 states that Carrima is used as a drug for the Iraqi-Ducha

Page 132 1358540 Schematic description of the characteristics of Kali musali and safed musali. Figure 22 illustrates the characteristics of different samples of Citrallus C〇1〇 Synthis. This feature indicates that the lack of some components is due to the standardization of the extraction process used for the same color source from the plant. Figure 23 illustrates the characteristics of different samples collected from different locations in the country, Holarrena Antidyssentric. This feature shows the effect of ecological factors on the chemical composition of the plant material. Figure 24 illustrates the characteristics of two temporal lobe samples from different locations. Flavonoids that occur over a 30-40 minute time period exhibit genetic, phenotypic differences and ecological factors in the chemical composition of the plant material. Figure 2 5 shows a photograph of an artificial satellite in India. These satellite photos indicate that India has different tropical climate zones. Figure 2 6 illustrates the characteristics of two formulations for cosmetics such as herbal shampoo. Figure 27 illustrates the characteristics of two different trademarks, TRIKATU. The difference in its s-test can be due to the difference in the composition of the TRIKATU. Figure 28 illustrates the characteristics of the turmeric and its three different commercial products. A common absorption peak appears in 2 of these features in all of these features. (Figures 2-9 to 9 show no characterization of all the drugs reported in Table 丨3)

Page 133 1358540 Brief description of the diagram Figure 29 illustrates the characteristics of the whole plant of both Abel moschus and Moschatus medium. Figure 30 illustrates two characteristics of the bark of the Acacia suma. Figure 31 illustrates the two characteristics of the young leaves of the Indian scorpion (Acaltpha indica). Figure 32 illustrates the two characteristics of the leaves of Adhatoda vasaka. Figure 33 illustrates two characteristics of the leaves of Adiantum caudatum. Figure 34 illustrates two characteristics of the stem bark of Ailanthus excelsa. 4 Figure 35 illustrates the two characteristics of the underground stem of Acorus calamus. Figure 36 illustrates two characteristics of a large single small bulb of Allium porum. Figure 37 illustrates two characteristics of small bulbs of garlic (Allium sativam). Figure 38 illustrates two characteristics of the underground stem of Alpinia galanga. Figure 39 illustrates two characteristics of the underground stem of 1^Alpinia officinarum. 〇 Figure 40 illustrates the two characteristics of the underground stem of Alpinia speciosa. Figure 41 illustrates the raw nut fruit of Areca catechu

Page 134 1358540 Schematic description - two characteristics. Figure 4 2 illustrates two characteristics of emulsion processing nuts in the floor. Figure 43 illustrates the two characteristics of the stem bark of 乂瑞卡卡提 reca kateeh). Heart Network Figure 44 illustrates the two characteristics of the same source of dye from Arnica. Figure 45 illustrates two features of the whole plant of the Bacopa monneri. Figure 4 6 illustrates two characteristics of the bark of the needle stalk. Figure 47 illustrates two characteristics of the entire plant of Borrhievia diffusa. Figure 48 illustrates the two characteristics of the large, peeled fruit of Capscicium Annum linn. Figure 49 illustrates the two characteristics of the 'unstripped fruit' of the large pepper. Figure 50 illustrates two characteristics of small, unstripped fruits of bell pepper. Figure 51 illustrates the two characteristics of the stem bark of the Coscinium fenestratum. Figure 52 illustrates the two characteristics of the roots and leaves of the Coccinidium gr*aridis. Figure 53 illustrates the two characteristics of the leaves of Dactlylactinium Aegyptium (erect). Figure 5 4 illustrates two characteristics of the leaves of the bamboo grass (prone). Figure 55 illustrates the characteristics of the leaves and bark of the genus Diristachis cineraria.

Page 135 1358540 Brief description of the diagram Figure 5 6 Statement of the exocarp of the fruit of Emb 1 i ca officinalis Figure 57 presents a dedication of a beauty cleansing cream Figure 58 states a beauty The two characteristics of the cleansing cream are shown in Fig. 59, which describes the two characteristics of Grissingiag. The two characteristics of the root bark of glabra. Figure 60 shows the two characteristics of Grischenya. Figure 61 illustrates the two characteristics of the whole plant of Jinnamasi vista (Sylvestrae). Figure 62 shows the two characteristics of the stems of Hollerona Antidysentrica. . Figure 63 illustrates the two characteristics of the roots of Innu Resimos r 'm v Innula recemosa. Figure 6 4 illustrates the characteristics of the Magnolia. Figure 65 illustrates the two characteristics of the leaves of Moringa 〇lifera. Two characteristics (G1ycerrhz i a o The whole plant's powder (Gymnema)

Two flowers of Michelia champaka) Figure 66 illustrates two characteristics of the same source of dye from MyriCa cerefera. Figure 67 illustrates two characteristics of the whole plant of Nahi axi 1 lae. Figure 68 illustrates the two characteristics of the bark of the wood butterfly (〇r〇xylum indicum).

Page 136 1358540 Brief description of the diagram Figure 69 illustrates the two characteristics of the leaves of Ocimum sanctum. Figure 70 illustrates the two characteristics of the leaves of the Pluchea lanceolata. Figure 71 illustrates two characteristics of the stem bark of Picrorrhiza kurroh. Figure 72 illustrates the two characteristics of the leaves of the Piper beetle. Figure 73 illustrates two characteristics of the seeds of Ps〇ralia cori 1 i fol ia. Figure 74 illustrates two characteristics of the leaves of the large dish (Raphanus sativus). Figure 75 illustrates two characteristics of the root of Ricinus cummunis. Figure 76 illustrates the two characteristics of stem and root of _@草(Rubia cordifolia). Figure 77 illustrates the two characteristics of the root of Saussrea lappa. Figure 78 illustrates two characteristics of the entire plant of Spheranthus indicus. Figure 7 9 illustrates two characteristics of the stem bark of s y m p 1 〇 c u s racemosus. Figure 80 illustrates two characteristics of the fruit of Terminalia chebula.

Page 137 1358540 Brief description of the diagram Figure 81 illustrates the two characteristics of the fruit of Terminal ia bel lerica. Figure 82 illustrates two features of the entire plant of Trigonella faenumg. Figure 83 illustrates the two characteristics of the stem and root of the (Tri) (Tribulus terrestrias). Figure 84 illustrates the two characteristics of the leaves of Tyloph ora asthmatica. Figure 85 illustrates two characteristics of the same source dye of the drug pod (Viburnum). Figure 86 illustrates the two characteristics of the roots of Withinia somnifera. Figure 8 7 illustrates the two characteristics of the underground stem of the processed Zinziber 〇fficinalis. Figure 88 illustrates two features of the powder of Avipattakara churna. Figure 89 illustrates the two characteristics of a herbal formula for Kamauga Ras. Figure 90 illustrates Kumarayasava—the two characteristics of the herb through the fermentation process. Figure 91 illustrates two characteristics of a herbal formula of Mahalakshmi vilas ras. Figure 92 illustrates two characteristics of a herb formulation of Suvarna yoga raj a Guggulu.

Page 138

1OJ0D4U Schematic description of the figure Figure 9 3 shows the characteristics of Anandreha Hirawi Ras>. Right click on any particular absorption (AnandabhairaVi software will show the x of the absorption peak), the image is on the bar code production. These coordinates are displayed on the ^ 8 coordinate axis, have been used and appear in the tool list. Approaching the absorption peak Figure 94 states that Crimy Coutarei displays a bar code value for a particular absorption peak. • The image software is presented in Figure 9.5 by Anand Bob Lavitu 96 stated by Crimicu The barcode of Tracy's f. Figure 97 shows the code of Annan Deborah Lavis. Figure 98 shows the display of Crimique Coutures. The two solid diagrams 9 show how the computer network will make the invention The database is applied in the enterprise resource planning and customer relationship management = the legal map produced by the law 100 stated in a collection of Indian smashed 'indica' in February. The soft leaves in the color strip diagram ' (Azadiracta Figure 1 0 1 Stated a herbal formula, Annan Deborah Ravi, = color f spectrum color bar graph of the new color chromatogram, Rees's drug in Figure 1 0 2 stated a herbal formula, Crimicut ^ New color chromatograms in color bar graphs Adams pharmaceutical FIG Chen said Kerry 103 meters Tela Reese library 104 of FIG. Annan Chen said primary de Swiss-dimensional Gaussian-shaped sea pull FIG Chen said Kerry 105 meters library Tela Reese

I color chromatographic cake

Page 139 1358540 Schematic description of the figure Figure 1 0 6 Chen Figure 1 0 7 Chen Figure 108 Chen Figure 1 0 9 statement the amount of the quantity that describes the amount of the damage that is used in a database and has been used (Du Xia)'s pie-shaped damage disorder (Du Xia)'s pie-shaped damage disorder (Du Xia)'s pie-shaped map with several kinds of herbal 3_D and contour images, for various corporate resources Project and customer relationship management applications. The 3D and outline images of several herbs are presented for various corporate resource plans and customer relationship management. Figure 1 1 0 states that this application is specifically for use in a database. Figure 1 1 1 illustrates the characteristics of the noisy cosmetic sample in 3-D and profile images. Figure 1 1 2 states that features of a parent pigment such as 3-D and contour images can be used to find the dilution of the master pigment. Figure 1 1 3 illustrates the characteristics of an isolated drug and its UV spectrum as represented by 3-D and contour images. Anti-therapeutic drugs are 3-D and contour images. Figure of the operation sequence of a software with several functions Figure 1 1 4 a pair of statements Figure 115 shows a table.

Page 140

Claims (1)

1358540 • (more) Correction VI. Application---- 1. A method for the detection and identification of structures derived from the natural source of extracts from plants or animals, using chromatographic identification techniques, The method comprises at least the steps of: i) extracting an organic or organometallic molecule using a suitable solvent; ii) extracting the extract obtained in step (i) by a separation using high pressure liquid chromatography; (iii) The components are based on the p Η value and polarity to understand the 3 - D chromatogram; iv) the resulting 3-D and contour chromatograms are imaged by a built-in soft color, from the individual colors of the above images The coordinates used are all the 3-D properties of the image to analyze the color image; v) the concentration of the various components that have been flushed out in time. vi) a chromatogram is generated from the analyzed color, along with the conjugate component There are peaks that appear at different residence times; 'vii) compounds that are recognized in the above components by the UV-visible absorption of the components in the image; ' viii ) according to their polar compounds A total of confirmation, classification and classification into polarity, excellent and low or non-polar i X) for a selected peak using the X-axis for the retention time, Y-axis length, R is the red image point, G is the green image point and B The blue image is used to generate the code; and X) generates a database of features and barcodes and confirms the compound in the sample. Or man-made eigenanalysis, such that the rotation is expressed in one to represent the degree; the symmetry of the sub is used to confirm the yoke property; Page 141 1358540 _ Case No. 90100326 _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ Alternatively, ethanol can be used for the standardization of drugs. 3. The method of claim 1, wherein the above features are developed to extract the same drug at different pH ranges. 4. The method of claim 1, wherein the high pressure liquid chromatography apparatus is selected from any commercially available high pressure liquid chromatography apparatus having an optical dipole array detector, preferably A pump with a gradient or ternary system. 5. The method of claim 1, wherein the pH and polarity of the mobile phase are changed by using an aqueous solvent, water or a desired p Η value by using a salt such as potassium phosphate or hydrogen phosphate. The buffer ratio of di-potassium and phosphoric acid to maintain the desired ρ Η value, and a non-aqueous solvent, is controlled from 0 to 100%. 6. The method of claim 1, wherein the non-aqueous, organic and aqueous, water or buffer at a known pH is used in step 1 (iii) and is based on its polarity range s Choice. 7. The method of claim 1, further comprising converting the above-described profile chromatogram into a color comprising a conjugated and polar nature of the study drug Page 142 1358540 _• Case No. 90100326_年月日日__ VI. Application for patent coverage Image. 8. As in the method of claim 1, a drug (single or compound) is evaluated by the amount of the component present in a particular polarity and ultraviolet-visible absorption region. ·· 9. If applying the method of item 1 of the patent scope, the software generates a code for one or more sets of peaks or images selected, using the X. axis as the retention time, the Y axis as the wavelength, and R as the red image point. G is the green image point and the B blue image point as coordinates, which are provided by the software to make the product property go to the enterprise. 10. The method of claim 1, wherein the software used above is called "rainbow" and has at least the following characteristics: (a) - the software has an opening from the folder in a different format (range) such as BMP , JPEG, TIF, GIF tomographic image capabilities, and analyzed in different colors appearing in the image with a single point sensitivity; (b) - the software has the ability to display the information of the image point in form 1 A chart with X (0- (min. time unit) and Y (200-800 nm) coordinates and 2. - a cake with two peaks in each of the separate columns with automatic or manual individual values (c) The ability of a software to print data generated by all analyses by using a printed image; (d) - the ability of the software to change the page settings of the print by using a page to set the image ; Page 143 1358540 Case No. 90100326 Issue Amendment VI. Patent Application (e)—The ability of the software to select a portion of the image and analyze it by using a re-evaluation image; (f) A software has any means for opening different images The number of image analysis windows and the ability of the status to be displayed in the window image; (g) - the software has the ability to distinguish the image into three regions in a 2 minute library * fine by the use area image; (h) - The software has the ability to reverse the selected image by using an inverted image; (Ο The software has the ability to convert the β-Hui image into Notepad 'Word pad and MS Word, by using the edit image; (j) a software with The ability to manipulate the features of the various operational information of the software by using the auxiliary image; and, (k) a software having the ability to store the generated data 'using the saved new image' into the .JPEG file format. A method in which a software is used for data processing of a chromatogram includes: a color contour image of a component and 3 _ D , and the above data processing method is at least packaged according to different Color (with the standard mentioned in the published notes a, · life cycle, plus, mentioned in the standard) to analyze (extract color) the color ίΐί image, and indicate the rolling of various ingredients that are rushed over time Secondary roots according to the polarity of the residence time; ^ the three-dimensional nature of all the drugs in the image to analyze the 3-D chromatogram of the 4*; 1358540 Nickname 90100326 VI. Scope of Application C. Produce a chromatogram with a number of polar sequences with / π occurring with the conjugate nature of the molecule presented at a read time; peaks appearing at different residence times d. Confirm the compound in the above molecule by the oath of the different components of the image; ', τ & light* ° and the property e. According to the polarity and conjugate properties of the molecule, the identification and the axis are divided into therapeutic regions. To correlate the therapeutic properties of the X and Y organisms in the study drug; the various components have been reported f. Use the coordinates of the image, ie the X axis is stagnation, R is the red image point, and G is the green image The point and B · s Y-axis are provided for the wave recommendation software, for the selected peak shame + orphan image point, by pushing τ from 玍 ~ bar code. g. The utility of generating a feature and bar code resource database for the sample For example, the enterprise resource plan library is arbitrarily h. For all the applications that have been used for commercial applications; and the relationship management type of sample generation -1, 3 enterprise resource planning and customer /, with display window' database. 1 2 · If the patent application scope is 丨丨. Item name, Rainbow, the new software is used for 31) and the 钤夂 method, wherein the above-mentioned use one provides a relief profile when there are retention on the X and γ axes. Analysis of the chromatogram of the software B /, wavelength. 13. As set forth in the U.S. Patent Application Serial No. U provides a percentage method for indicating the =, wherein the above analysis uses a 3D and contour chromatogram. The new software of the degree of knowledge is 1358540 _ case number 90100326_年月日日__ VI. Patent application scope 14. The method of claim 1 of the patent scope, wherein the above-mentioned software called 'Rainbow' At least the following features: i. A software having the ability to open tomographic features in different formats (ranges) such as BMP, JPEG, TIF, GIF from the folder, and having a single point of view sensitivity in the image Different colors to analyze the image ii. A software has the ability to display the information of the image point, in the form of 1. One having X (0- (min. time unit) and Y (200-800 nm) coordinates Chart and 2. - Pie chart with individual values for each peak automatically or manually in two separate columns next to the graph; ii i. The ability of a software to print data generated by all analyses by using a column Print image; i v. - the ability of the software to change the page settings of the print by using a page to set the image; v. a software having the ability to select a portion of the image and analyze it by using a re-evaluation image; a soft The ability to open any number of image analysis windows and states for viewing on a window image for different images; vi i. A software has the ability to distinguish the image into three regions over a 20 minute range, using the region image ; viii · The software has the ability to reverse the selected image using the inverted image; ix. - the software has the ability to convert the image into Notepad, Word pad and MS Word, by using the edit image; Page 146 1358540 Case No. 90100326 修正 Amendment 6. Patent Application X. — The ability of the software to have features relating to various operational information on the operation of the software, by using auxiliary images; and xi. A software has the effect of storing the generated Data, the ability to create a .JPEG file format by using a new file. 15. A computer method for the standardization of chromatographic characterization, chemistry and therapy, and bar code fabrication of organic or organometallic molecules from a plant, animal or a naturally available or artificially achievable material, the method comprising at least: a) selection of the drug and extraction of the component; b) separation of the component into individual components to produce an ultraviolet-visible spectrum of the individual component, followed by the 3-D of the individual component from the ultraviolet-visible spectrum of the individual component Contour map, and convert the 3-D and contour map into identification features; c) analyze the feature with a developed software, wherein the developed software has the following characteristics: i. A soft body has an open tomographic feature image to Different formats (range) capabilities such as BMP, JPEG, TIF, GIF are from the folder and are analyzed in different colors appearing in the image with a single point sensitivity; ii. A software has the display The ability of phase information to be in the form 1. A graph with X (0- (min. time unit) and Y (200-800 nm) coordinates and a pie chart with each peak Automatically or manually separate the two individual number next to the bar graph in; Page 147 1358540 ._Case No. 901Q0326_年月日日__ VI. Patent Application ii i. A software has the ability to print data generated after all analyses by using a printed image; i v. —Software The ability to change the page settings of the print by using a page to set the image; v. - the software has the ability to select a portion of the image and analyze it by using a re-evaluation image; vi. - the software has been turned on for different images The ability of any number of image analysis windows and states to be displayed in a window image; vi i. - the ability of the software to distinguish the image into three regions in the range of 20 minutes, by using the region image; vi ii. The software has the ability to reverse the selected image using the inverted image; ix. - the software has the ability to convert the image into Notepad, Word pad and MS Word by using the edit image; X. A software has operations on the software The ability to apply various features of the information by using the auxiliary image; and xi. - the software has the data stored, and by using the saved new image, the .JPEG The ability of the file format; and d) the interpretation of the data obtained. 16. The method of claim 15, wherein the chemical analysis of the components of the study drug, and the co-consumption and polarity properties of the drug are provided by using the developed new software. Page 148 1358540 _ Case No. 90100326_年月日日_Amendment _ VI. Patent application scope 17. The method of claim 15, wherein the above-mentioned new concept of providing a chromatographic identification method for herbal medicine helps to quickly confirm The actual profile of the compound being used in the drug. 18. The method of claim 15, wherein the above-mentioned use of the herbal and formula outline and 3-D chromatogram, the chromatogram developed from a high pressure liquid chromatography analyzer optical couple A polar array detector provides a new chromatographic method for identifying one of the herbs and formulations, describing data describing the specific properties of the ingredients in the herb, and rushing in a particular order of polarity under similar experimental conditions. 19. The method of claim 15, wherein the ultraviolet-visible spectrum of the compound provided by the above method has been shown to have a conjugate and polar nature of the molecule and an individual concentration of the molecule accompanying the polarity of the molecule. The method of claim 15, wherein the ultraviolet-visible spectrum of all the components provided by the above method is displayed in a single image "chromatographic identification feature", the above characteristics are changed into an herb or a formulation The blueprint of the ingredients can be used as a test and rapid confirmation of the study drug. 21. The method of claim 20, wherein the above parameters are analyzed by the same standard, such as extraction with the same solvent ethanol, the same experimental time 0-6 minutes, the same phase is accompanied by a pH range of 5. 5 -7. 5 phosphate buffer and a similar UV-Vis range 200-800 Page 149 1358540 _ Case No. 90100326_Yearly 曰 Amendment _ VI. Application for patent range nm for characterization and standardization of chemistry and treatment. 22. The method of claim 20, wherein the feature identification described above can be used for the study of noisy, alternative, contractual, and commercial food and drug samples and to confirm their purity and impurities. : 23. The method of claim 20, wherein the above-described characterization method has been used to confirm that the ingredients are for process standardization, quality management behavior and anti-therapeutic, Ajal, homeopathic Standardization of the treatment of drugs in Shedha, Younani, China, Tibet, and Kanpo (Japan). 24 For example, in the method of claim 20, wherein the above-mentioned characterization method can be used to study the difference in chemical composition due to ecological factors, factors of euphoria, genotype and phenotypic changes caused by naturally occurring samples ( In plants), and to confirm and standardize the chemical components therein. 25. The method of claim 20, wherein the characterization is used to study the chemical composition of the synthetic sample and to standardize and normalize the chemical composition therein for the appropriate chemistry and treatment. The method of claim 20, wherein the above characterization has been used to study the chemical composition of the herbal product of a single drug sample and to confirm the chemical composition of the chemical components therein. Page 150 1358540 _ Case No. 90100326_年月曰_ί±ί._ VI. Patent Application Area 27. The method of claim 20, wherein the above identification has been used to study the herb in the compound drug sample. The chemical composition of the product and the chemical standardization of the chemical components in it are confirmed. 2 8. The method of claim 20, wherein the feature identification method has been used to study the difference in chemical composition in a biological sample and to confirm and normalize the chemical composition therein. 29. The method of claim 20, wherein the characterization method has been used to study the difference in chemical composition between single and compound food and drug samples of the trademark product and to confirm and standardize the chemical composition therein. 3 如 As in the method of claim 20, one of the large sample database preparations provides a number of generalizations for a particular plant group, which are grouped together by a particular disease or treatment classification. 31. The method of claim 20, wherein the characterization of the drug aids in classifying a component of a drug and the component is based on polarity and conjugation from a 3-D and contour chromatogram Quantify and evaluate the effect (damage) of the drug on body fluids. 32. The method of claim 20, wherein the characterizing is identifiable, and the physical chemistry of the drug, such as color, is resolved and normalized. Page 151 1358540 _+ Case No. 90100326_Yearly 曰 Amendment _ VI. Scope of Patent Application The standardized use of the treatment of bodily fluids utilizes the conjugate and polar properties provided in the chromatographic features. 33. The method of claim 20, wherein the above characterization identifies and normalizes the physical chemistry of the drug, such as the taste, acid, salt, spicy, bitter, and sputum (eg, Standardization of treatment for Allah, Lavala, Kathu, Ticeta, and Caxia, respectively referred to in Ajal, using the symmetry and polarity properties shown in the chromatographic features 34 The method of claim 20, wherein the above characterization can understand and standardize physical chemistry of the drug such as properties, potencies, metabolites, specific properties such as optical activity of the molecule (Guna, Vera, Verapaka, Prabhavar) Standardization for this treatment utilizes the entire drug exhibited by the conjugate and polar properties of the individual components in the chromatographic features. 35. The method of claim 20, wherein the above characterization can be used to understand and standardize the physico-chemical properties of the drug (Gunas) such as cold, hot, slow-acting, intense, heavy Light, soft, smooth, supple, dry (Guna's such as Xita, Youxun, Manda, Tikena, Gulu, Lagu, Snigoda, and Luksharu Standardization for this treatment, as described in Ajalta, utilizes the conjugate and polar properties of the drug as shown in the chromatographic features. Page 152 1358540 _ Case No. 90100326_Yearly revision _ Six, the scope of application for patents 36. A software has been used for a part of the color contour image and 3-D chromatographic data processor, the above processor at least Includes calculation tools and the following capabilities: i) an analyzer (extracted color) for the analysis of the color contour image according to the choice of different colors (with the mentioned standards in the published notes, life cycle, processing) The concentration of the component that is rushed over time and the polarity according to the residence time; ii) an analyzer analyzing the 3-D chromatogram of the drug using all of the three-dimensional properties of the image; iii) a tool with respect to generating one Many chromatograms appearing at peaks of different residence times with a conjugated nature of the molecules oscillated over time in a well-defined polarity sequence; iv) - the identifier for ultraviolet-visible light with different components in the image Absorbing properties to identify compounds in the above molecules; v) - the tool will characterize X according to the polarity and conjugate properties of the molecule And the Y-axis is divided into therapeutic regions to make the various components of the study drug have been reported to be related to the nature of the treatment; vi) - the tool uses the coordinates of the image, ie the X-axis is the retention time and the Y-axis is the wavelength. R is a red image point, G is a green image point, and B is a blue image point, provided by the recommended software, generating a code for the selected peak; vii) generating a database of features and barcodes for the sample to enhance various Database utilities such as enterprise resource planning and customer relationship management applications; and Page 153 1358540 Case No. 90100326 Year Month a Amendment VI. Patent Application v i i i ) Generate a database with 'display windows' for all samples of enterprise resource planning and customer relationship management that have been used for commercial applications. 37. The data processor of claim 36, wherein the solvent used for the extraction is selected based on its polarity, the hydrophilicity and hydrophobicity of the component, the sample and its components. 38. The data processor of claim 36, wherein the high pressure liquid chromatography apparatus used above is selected from any commercially available high pressure liquid chromatography apparatus having an optical dipole array detection. Preferably, it is a pump with a gradient or ternary system. 3. The data processor of claim 36, wherein the polarity of the mobile phase of a non-aqueous solvent and a specific p-valued aqueous solvent is changed by changing an aqueous solvent such as water or a known ρ The ratio of the devaluation buffer to a non-aqueous solvent is controlled from 0 to 100%. 40. For the data processor of patent application No. 36, wherein the above uses a new software for 'Rainbow' for 3D and contour tomography analysis, the software provides a retention on the X and the Υ axis. Chromatography of time and wavelength. 41. The data processor of claim 36, wherein the use of the above provides a 3D. and contour chromatogram analysis by providing a new software that can indicate the degree of damage in summer. Page 154 1358540 _ Case No. 90100326_Year of the month __ VI. Patent application scope 42. For the data processor of claim 36, a single solvent ethanol can be used to extract the component; the same analytical conditions and instruments Parameters have been used for all samples to standardize the proposed treatment. Thereby achieving standardization of the treatment. 43. The data processor of claim 36, wherein the software described above using the rainbow has at least the following characteristics: (a) the software is named 'Rainbow. (b) - the software has a different format (range) Such as BMP, JPEG, T IF, GIF, the ability to open a tomographic image from the folder, and analyze the image with different colors appearing in the image with a single point sensitivity; (c) a software with The ability to display the information of the image point is in the form of 1. A chart with X (0- (min. time unit) and Y (200-800 nm) coordinates and a pie chart with each peak automatically Or manual individual values in two separate columns next to the figure; (d) - the ability of the software to print the data produced by all analyses by using a list of prints; (e) - the software has a change print The ability to set a page by using a page to set the image; (f) a software having the ability to select a portion of the image and analyze it by using a re-evaluation image; (g) - the software has any number of images open for different images Image score Page 155 1358540 Case No. 90100326 6. The application scope analysis window and status are displayed in the window image; (h) - the software has the ability to distinguish the image into three regions at a distance of 2 minutes, by using the area image; A software has the ability to reverse the selected image using the inverted image (j). The software has the ability to convert the image into N〇tepad, word pad and MS Word, using the edit image; (k) a software with The ability of the software to operate various features of the operational information, using auxiliary images; and (l) a software having the ability to store the generated data, using the saved new image 'in a .JPEG file format. 44. The data processor of claim 36, wherein the use of the rim of the above chemical music and the characteristics of the 3~~D chromatogram is the basis for confirmation of the chemical composition. Page 156