TWI354782B - - Google Patents
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- Publication number
- TWI354782B TWI354782B TW096134557A TW96134557A TWI354782B TW I354782 B TWI354782 B TW I354782B TW 096134557 A TW096134557 A TW 096134557A TW 96134557 A TW96134557 A TW 96134557A TW I354782 B TWI354782 B TW I354782B
- Authority
- TW
- Taiwan
- Prior art keywords
- optical waveguide
- layer
- sample
- type surface
- waveguide type
- Prior art date
Links
- 230000003287 optical effect Effects 0.000 claims description 82
- 239000000758 substrate Substances 0.000 claims description 27
- 238000011068 loading method Methods 0.000 claims description 26
- 229910052751 metal Inorganic materials 0.000 claims description 17
- 239000002184 metal Substances 0.000 claims description 17
- 239000000463 material Substances 0.000 claims description 14
- 238000005259 measurement Methods 0.000 claims description 14
- 230000002745 absorbent Effects 0.000 claims description 8
- 239000002250 absorbent Substances 0.000 claims description 8
- 229910000420 cerium oxide Inorganic materials 0.000 claims description 8
- BMMGVYCKOGBVEV-UHFFFAOYSA-N oxo(oxoceriooxy)cerium Chemical compound [Ce]=O.O=[Ce]=O BMMGVYCKOGBVEV-UHFFFAOYSA-N 0.000 claims description 8
- 239000000020 Nitrocellulose Substances 0.000 claims description 5
- 229920001220 nitrocellulos Polymers 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 4
- 230000013011 mating Effects 0.000 claims description 4
- 108020004707 nucleic acids Proteins 0.000 claims description 4
- 102000039446 nucleic acids Human genes 0.000 claims description 4
- 150000007523 nucleic acids Chemical class 0.000 claims description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims description 3
- 239000000956 alloy Substances 0.000 claims description 3
- 229910045601 alloy Inorganic materials 0.000 claims description 3
- 229920002120 photoresistant polymer Polymers 0.000 claims description 3
- 239000002861 polymer material Substances 0.000 claims description 3
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- 102000004169 proteins and genes Human genes 0.000 claims description 3
- 239000011521 glass Substances 0.000 claims description 2
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- 108090000765 processed proteins & peptides Proteins 0.000 claims description 2
- RAHZWNYVWXNFOC-UHFFFAOYSA-N Sulphur dioxide Chemical compound O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 2
- 235000010269 sulphur dioxide Nutrition 0.000 claims 2
- 239000004291 sulphur dioxide Substances 0.000 claims 2
- 239000000523 sample Substances 0.000 description 42
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 description 22
- 239000000243 solution Substances 0.000 description 8
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- 230000007246 mechanism Effects 0.000 description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 238000001514 detection method Methods 0.000 description 4
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 4
- 229910052737 gold Inorganic materials 0.000 description 4
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- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 description 2
- 229910052684 Cerium Inorganic materials 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 239000012491 analyte Substances 0.000 description 2
- 239000000427 antigen Substances 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 108091007433 antigens Proteins 0.000 description 2
- 238000005102 attenuated total reflection Methods 0.000 description 2
- 238000005842 biochemical reaction Methods 0.000 description 2
- 229910052796 boron Inorganic materials 0.000 description 2
- GWXLDORMOJMVQZ-UHFFFAOYSA-N cerium Chemical compound [Ce] GWXLDORMOJMVQZ-UHFFFAOYSA-N 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 238000013461 design Methods 0.000 description 2
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- 238000001459 lithography Methods 0.000 description 2
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- 239000011148 porous material Substances 0.000 description 2
- 239000004065 semiconductor Substances 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 241000323253 Avian leukosis virus ev/J Species 0.000 description 1
- 238000000018 DNA microarray Methods 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241001415849 Strigiformes Species 0.000 description 1
- 229920006221 acetate fiber Polymers 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000002238 attenuated effect Effects 0.000 description 1
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- 229920002301 cellulose acetate Polymers 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
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- 238000007877 drug screening Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 229910052741 iridium Inorganic materials 0.000 description 1
- GKOZUEZYRPOHIO-UHFFFAOYSA-N iridium atom Chemical compound [Ir] GKOZUEZYRPOHIO-UHFFFAOYSA-N 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 230000001546 nitrifying effect Effects 0.000 description 1
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- 238000002310 reflectometry Methods 0.000 description 1
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- 229910052709 silver Inorganic materials 0.000 description 1
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- 238000001228 spectrum Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
- G01N21/552—Attenuated total reflection
- G01N21/553—Attenuated total reflection and using surface plasmons
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW096134557A TW200912279A (en) | 2007-09-14 | 2007-09-14 | Optical waveguide-type surface plasma resonance sensing device |
| US12/076,203 US7679749B2 (en) | 2007-09-14 | 2008-03-14 | Optical waveguide surface plasmon resonance sensor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW096134557A TW200912279A (en) | 2007-09-14 | 2007-09-14 | Optical waveguide-type surface plasma resonance sensing device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW200912279A TW200912279A (en) | 2009-03-16 |
| TWI354782B true TWI354782B (https=) | 2011-12-21 |
Family
ID=40454086
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW096134557A TW200912279A (en) | 2007-09-14 | 2007-09-14 | Optical waveguide-type surface plasma resonance sensing device |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US7679749B2 (https=) |
| TW (1) | TW200912279A (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI657278B (zh) * | 2013-08-20 | 2019-04-21 | 美商通用電機股份有限公司 | 電漿界面及製造電漿界面的方法 |
| TWI680285B (zh) * | 2014-05-21 | 2019-12-21 | 美商康寧公司 | 稜鏡耦合系統及用於對層深度大的波導件標定特徵之方法 |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI428600B (zh) * | 2009-09-11 | 2014-03-01 | Forward Electronics Co Ltd | 生物微流道檢測裝置及其分子檢測方法 |
| JP2012021936A (ja) | 2010-07-16 | 2012-02-02 | Toshiba Corp | 光導波路型センサチップおよび光導波路型センサ |
| US8965737B2 (en) | 2011-10-28 | 2015-02-24 | International Business Machines Corporation | Ultrasensitive biological and chemical detection using surface plasmon resonance |
| CN103376244B (zh) * | 2012-04-18 | 2016-09-21 | 中国科学院电子学研究所 | 表面等离子体共振芯片及应用该芯片的传感器 |
| TWI512963B (zh) | 2014-01-13 | 2015-12-11 | Univ Nat Taiwan | 光偵測器 |
| US9348099B2 (en) | 2014-07-18 | 2016-05-24 | Intel Corporation | Optical coupler |
| JP2016148655A (ja) * | 2015-02-05 | 2016-08-18 | 日東電工株式会社 | 計測装置 |
| CN107422403B (zh) * | 2017-09-21 | 2019-12-03 | 京东方科技集团股份有限公司 | 用于控制光出射方向的光学部件及其制造方法 |
| CN110045107B (zh) * | 2019-04-28 | 2021-12-07 | 南京信息工程大学 | 基于等离激元效应波导的实时生物检测装置及制备方法 |
| TWI898330B (zh) * | 2023-11-22 | 2025-09-21 | 農先生技股份有限公司 | 具高靈敏度的半抗原檢測方法及裝置 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6330064B1 (en) * | 2000-03-13 | 2001-12-11 | Satcon Technology Corporation | Doubly-differential interferometer and method for evanescent wave surface detection |
-
2007
- 2007-09-14 TW TW096134557A patent/TW200912279A/zh not_active IP Right Cessation
-
2008
- 2008-03-14 US US12/076,203 patent/US7679749B2/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI657278B (zh) * | 2013-08-20 | 2019-04-21 | 美商通用電機股份有限公司 | 電漿界面及製造電漿界面的方法 |
| TWI680285B (zh) * | 2014-05-21 | 2019-12-21 | 美商康寧公司 | 稜鏡耦合系統及用於對層深度大的波導件標定特徵之方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| TW200912279A (en) | 2009-03-16 |
| US20090073420A1 (en) | 2009-03-19 |
| US7679749B2 (en) | 2010-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Annulment or lapse of patent due to non-payment of fees |