TW471957B - Non-invasive blood pressure measuring method and device thereof - Google Patents

Abstract

The present invention relates to a non-invasive method for measuring blood pressure and a device thereof. The method mainly comprises using a stagewise pressurization and depressurization procedure and using curve fitting method to obtain a pulse encapsulated curve based on the sampled pulse composite wave; and using this encapsulated curve to determine the systolic pressure and the diastolic pressure. A blood pressure measuring device according to this measuring method can achieve the effects of comfortable, fast and accurate in blood pressure measurement.

Description

471957 V. Description of the invention (l) ------- [Scope of creation] I: Department of a non-invasive blood pressure measurement method and device 2. ::; mining! Segmented blood pressure measurement method and device for achieving comfortable and accurate measurement. [Background of creation] The human heart is a pulsating tube. The blood is intermittently pressed into the artery with each periodic contraction of the myocardium, and an irregular waveform of the pressure pulse wave (pu) is formed in the arterial system. i se wave), and at the same time, it also causes the artery to flex or vibrate (〇sc 1 1 iate). The baseline pressure presented in the pulse wave is the so-called diastolic pressure—approximately 80 miuHg, and the highest pressure is the systolic pressure—approximately 120mmHg. The difference between these two pressures—about 40 mmHg—is called pulse pressure; the other is called, mean arterial pressure (MAP) represents the blood pressure value weighted by time. It is known that there are various blood pressure measurement methods and devices that can measure the above-mentioned different blood pressure values. The most common way is to use a flat thin bag (cu ff) tied to the upper arm to compress the arteries in the arm after inflation. The blood flows, and then the gas in the thin bag is gently released, and the sound of the pulse is listened to by the stethoscope. This is the so-called Korotkoff sound. This Korotkoif sound is the sound that accompanies the normal flow of the liquid. If the pressure is further reduced, this Korotkoff sound will not be heard. So when you hear the first Korotkoi f sound, the thin bag pressure represents the systolic pressure.

Page 5 471957 V. Description of the invention (2) Diastolic blood pressure can be measured when K 〇 r 〇 t k o f f is not heard. The above method of measuring blood pressure is generally called " auscultatory method.

Auscultation can be applied to an electric blood pressure measurement device. A thin pump can be used to automatically inflate a thin bag 'and then convert a Korokoko sound into an electronic signal by a loudspeaker and detect it by a circuit'. Systolic and diastolic blood pressure were measured. Of course, there are many other blood house measurement methods, for example, one is to measure blood pressure by Doppler sh ifts caused by ultrasound reflection from the arterial wall. Another method is to insert the instrument directly. Blood pressure is measured in the blood vessels. But 'in addition to the 11 auscultation methods mentioned above, the other most commonly used blood pressure measurement method is the so-called osci1lometric method. Pulsation, that is, the change of the thin bag can be reached from the artery (comp (peak When the step is raised, the principle of the pulse wave mode is based on the fact that the injection of blood into the heart will cause the arteries to be adjacent to or located in the arm area covered by a thin bag. The pulsations of Huazao 4 will pass through the body, and this small change and thin bag carry,

= Place: The pressure transmitter—H pulsation is changed. This pulsation is called composite iexes) ’has been found to have -to-peak amplitude) ☆ From„

At the maximum value, physiologically, the complex wave caused by the thin bag pressure between systolic and diastolic pressure is present; in MAP; further, it has a special value J ^ 1 with systolic pressure and diastolic migration. The method " is based on extracting and testing the different generations / # 关 士 系. Therefore, '' u / composite wave vibration at pressure of the guide bag

471957 V. Description of the invention (3) Measurement of blood pressure value However, the continuous inflation of the above thin bag is generally inflated until it is tested for hypertension. There is considerable pain in the thin bag for a period of pain. The sense will be more uneconomical and effective for the user, and the method that the product cannot take into account the person's "pulse wave" has a blood pressure value that is much higher than the normal close of 180 ramHg to 240m. However, the discomfort, The reason is that the arm is tightly bound, creating blood pressure, especially for more serious and even more serious injuries. In addition, the design that does not need to be pressurized to that nature causes its disadvantage, which is that it needs to reduce the pressure when measuring. Value, for safety reasons, mHg varies, in order to meet the energy. So the blood pressure is caused by the inflation pressure is too high, so that the user must endure quite obese people. The blood pressure patients are also quite high in pressure, but because there are uncomfortable conditions in use, compared with the requirements of people's material life today, blood pressure measurement methods have been improved for many years. The need for improvement, how to take into account the accurate blood pressure measurement to make it more comfortable during the measurement process is relatively important. [Creation purpose and overview] In view of this, the purpose of this creation Provided is a blood pressure measurement method and a device that take both comfort and accurate measurement into consideration. According to the above-mentioned purpose of the present invention, a blood pressure measurement method provided includes the following steps: (a) applying a pressure to compress an artery of an object to block Blood flow in the arteries; (b) Continuously reducing the pressure on the arteries so that a gradually increasing blood flow can be produced in the arteries; (c) Detection during the above-mentioned hypotensive process

Page 7 471957 V. Description of the invention (4) Measure the pulses of different pulses into amplitude waves, and obtain the average motion of the pressure to the body and obtain the curve (the sci sealing curve is determined according to an inflatable plus a pressure transmission system). The internal pressure of the thin bag is higher than different pressure devices of 20 ~ 40mmH, which is connected to the curve fi 11 envelop which processes the voltage signal and amplitude wave. (D) Turn a voltage signal; (e) Process the voltage signal to form a series of vibrations and form a curve based on the peak value of each amplitude wave; (f). Repeat all steps to obtain the curve until the applied pressure is higher than the vein pressure (MAP) —predetermined value, for example, a curve of 20 ~ is sufficient to draw a pulsatile envelope envelop by curve fitting; and (g) systolic and diastolic blood pressure based on the pulsatile envelope. ❿ For the purpose of the above-mentioned creation, the blood pressure measurement device provided includes a thin bag for pressure and venting, a controller, a detector, a device, a processor, and a calculator. The controller is used to control the force, so that the thin bag can be pressurized and released in sections until the average arterial pressure (MAP) of the thin bag inflated object-a predetermined value, such as g; The pulsation caused by the back pressure of each artery on each time when pressure is applied; the pressure is transmitted to the thin bag to convert the pulsation into a voltage signal; and then a series of amplitude waves are formed by the processor number, and each peak value is based on each period of pressure release Connected into a curve, and the obtained curve is sufficient to draw a pulsation envelope curve (oscillometric: Finally, the heart pressure is determined by the calculator according to the pulsation envelope curve. Among them, the above obtained curve includes at least the amplitude as the vertical A rising curve, a curve with extreme values, and a falling curve plotted on the axis, and the average arterial pressure is a maximum value calculated from the aforementioned extreme curve

471957 V. Description of the invention (5) 〇 In order to make the above and other objects, features, and advantages of this creation more comprehensible, a preferred embodiment is given below in conjunction with the accompanying drawings for detailed description as follows. [Explanation of creation] Please refer to "Figure 1", which shows the corresponding relationship curve shown in the conventional measurement of blood pressure with time as the horizontal axis and the pressure or pulsation amplitude of inflation in the thin bag as the vertical axis. Icon. As shown in the figure, from the time T 0 when the blood pressure measurement is started, the thin bag needs to be continuously inflated and pressurized to a high pressure value PH preset by the sphygmomanometer. The M force value of this time is generally speaking. In order to ensure that the sphygmomanometer can measure the blood pressure of hypertension patients, it must be set to be much higher than the systolic blood pressure PS of normal human body, otherwise the dilemma of systolic blood pressure in patients with hypertension may occur. For example, P may be set to 1 80mmHg or higher value> Then, within the time T1 ~ T2 when the pressure in the thin bag is released, a pulsation will occur according to the aforementioned arteries. By measuring the amplitude of the complex wave at each different time point, The oscillometric envelop of curve 10 can be obtained by connecting the peaks. Finally, at time T2, it is known that the pressure has dropped to a sufficiently low value PL, for example, when the diastolic pressure PD is much lower than that of a normal human body, the pressure in the thin bag is completely released, and the measurement stroke of the entire sphygmomanometer is ended. . The conventional measurement method focuses on how to accurately obtain the pulsation of the counterpressure of the arteries during the pressure release process, so that the envelope curve drawn can be used to determine the systolic blood pressure PS and the diastolic blood pressure PD using various calculation methods. . However, the inflation pressure of the conventional blood pressure measuring device is to contract

Page 9 471957 V. Description of the invention (6) The pressure is the basis, so it is impossible to avoid a high inflation pressure. Please refer to "Figure 2" again. In contrast, the method for blood pressure measurement according to the present invention can clearly see the differences, that is, the method of segmented pressure is used, as in the preferred embodiment, the continuous operation is divided into three segments. Pressure section. In the first stage of pressurization, only the pressure is first increased to a Pi value, and then the pressure is released to a p2 value within the time ti to 12. The main purpose of this stage of pressure release is to pulsate the energy including diastolic pressure. The curve Ctl can be regarded as a descending curve close to T2 time with respect to the envelope curve 10 in FIG. 1. Then, when the pressure drops to P2, the pressure value is increased to a value of ρ3 exceeding 91 through inflation and pressurization, and then the pressure is released to a value of ρ4 within the time t3 to t4, which is just right in this preferred embodiment. The pulsating wave curve Ct2 containing the MAP obtained during the pressure release process in this section can be regarded as a section curve that generates an amplitude maximum value relative to the envelope curve 10 in FIG. 1. According to the curve Ct2, a MAP value can be calculated, and the disk pressure measurement method of the present invention uses the obtained MAP as a basis for determining the last stage of pressurization to a p5 value, that is, p5 is equal to the MAP plus a predetermined value. . Finally, the pressure is released to a p6 value within the time% to%, and the pulsation wave curve Ct3 including the contracted pressure is also measured during the pressure release process, and the measurement stroke of the entire sphygmomanometer is ended. Please refer to "Figure 3" again. According to the three-section curves Ct !, Ct2, and Ct3 in Figure 2, a _ shape with the pulse wave amplitude as the vertical axis and the thin bag pressure as the horizontal axis, and the curve ctl can be regarded as the corresponding The thick cpl curve, similarly, ct2 corresponds to cp2, and ct3 corresponds to cp3. Then, according to the pulse peak values obtained on cpl, cp2, and cp3, the pulsation envelope curve 30 can be obtained by a curve fitting method. Similar to the conventional methods, the enveloping curve 30 can determine the diastolic pressure PD and systolic pressure Ps.

Page 10 471957 V. Description of the invention (7) Analyze the differences between the blood pressure measurement method of the present invention and the conventional knowledge. The conventional knowledge is shown in Figure 1. Because it is impossible to know where the maximum systolic blood pressure measurement of the human body falls, Considering that it is suitable for various situations, the pressure of thin bag inflation must be set to a high value, 180minHg or even 240mmHg. However, for normal people, the systolic blood pressure may be around 1 30 mmHg, or for patients with suspected hypertension, the systolic blood pressure may be 160 mm H g or higher, but the point is that anyone can accept the same when measuring blood pressure. It is not a short process of pressing the arm with a high-pressure inflatable thin bag. Although the compression time can be shortened by fast inflation, it still needs to go through the high-pressure section and slowly release the pressure from the thin bag until the entire measurement stroke is completed. In addition, the blood vessels are pressurized by high pressure again and again, resulting in fatigue fatigue, which makes continuous blood pressure measurement impossible, otherwise there may be inaccuracies. In contrast, in the segmented measurement method adopted in the present invention, the highest thin bag inflation pressure, as the aforementioned p5, is not maintained above the MAP-predetermined value, which is set at, for example, 20mmHg ~ 40mmHg For a normal person with a MAP value of about 110 mm H g, with the measurement method of the present invention, as long as the inflation pressure reaches about 140 mm Hg, blood pressure can be easily and comfortably measured. The reason is that in the process of segmented pressure release, a curve such as the aforementioned Ct2 (Cp2) is bound to be obtained. This is an extreme value curve. From the Ct2 (Cp2) curve, the MAP of the object to be measured can be obtained first. Under general MAP with? ; In addition, the present invention must obtain another upward curve wct3 (cpl) and a downward curve such as ctl (cp3) in the process of stepwise pressure increase and pressure release, so the envelope curve 30 can be obtained by using curve fitting. At the same time, once an extreme value curve is obtained in the process of segmented pressure release, the inflation pressure value of the next stage of pressure release only needs to be increased from p4 to Ps equal to MAP plus a preliminary

Page 11 471957 V. Description of the invention (8) Setting value. In this way, the disadvantage of the uncomfortable measurement process is improved. Furthermore, according to the above-mentioned method of segmented blood pressure measurement, it can be seen that it provides the function of fuzzyc ο ntr ο 1. The maximum inflation pressure of the thin bag must be divided by The process of segment measurement is determined by different measurement strokes for different objects to be measured. In addition, if the pulse wave sampled during the stepwise pressure release process is accurate enough, it will not only shorten the time of the pressure release stages L ~ t2, t3 ~ t4, and 1: 5 ~ t6, but also speed up the blood pressure measurement. The enveloping curve obtained by curvefi 11 ing can also truly reflect the situation of vascular backpressure pulsation, so the determined systolic and diastolic blood pressure will be quite accurate. Of course, in the case of Fig. 2, it is preferable to obtain the Ct2 curve in the second stage of pressure release process, and only three stages of pressure release in the entire blood pressure measurement stroke to obtain the envelope curve 3 0 In different situations, there may be more than three stages of stepwise pressure release to measure blood pressure. In addition, in Figure 3 of the preferred embodiment, it is possible that Pβ or Ps falls on the Cpl or CPi curve of the sample, respectively, but it is also possible? ! > * PS is not included in the sampled pulse wave curve, but the envelope curve 3 Ο can also be obtained through the curvefi 11 ing step, and the final measured blood pressure value P is determined by the envelope curve 30 [] And Ps. Finally, according to the above-mentioned blood pressure measurement method of the present invention, a blood pressure measurement device can be correspondingly designed, which includes a thin bag that can be pressurized and deflated, a controller, a detector, a pressure transmitter, A processor as well as a calculator. The thin bag is usually wrapped around the arm of the human body, and the controller is used to control the pressure in the thin bag, so that the thin bag can be pressurized and released in sections until the inflation pressure of the thin bag is higher than the average arterial pressure (MAP) of the human body. Predetermined value, for example, 20 ~ 40mmHg; Detect the thin bag with a detector at each stage when the pressure is released.

Page 12 471957 V. Description of the invention (9) The pulsation caused by the back pressure of each artery at different pressure values. A pressure transmitter is connected to the thin bag to convert the pulsation into a voltage signal, and then the processor processes the voltage signal to form a series of amplitude waves, which are connected to each other according to the value of each amplitude wave during each pressure release. Curve, and the obtained curve is sufficient to draw a pulsating envelope curve from curvefi 11 ing. Finally, the systolic and diastolic blood pressure are determined by the calculator based on the pulsation envelope curve. Although this creation has been disclosed as above with a preferred embodiment, it is not intended to limit this creation. Anyone skilled in this art can make some changes and retouching without departing from the spirit and scope of this creation. Therefore, this creation The scope of protection shall be determined by the scope of the attached patent application.

Page 13 471957

Page 14

Claims (1)

471957 VI. Scope of patent application 1. A non-invasive blood pressure measurement method, including at least the following steps: applying a pressure to compress an artery of an object to block blood flow in the artery; continuously reducing the pressure on the artery makes the artery A gradual increase in blood flow can be generated in the process; during the above-mentioned depressurization process, the pulsation generated by each arterial back pressure at different pressure values is detected; the pulsation is converted into a voltage signal; the voltage signal is processed to form a series of amplitude waves And connect a curve according to the peak value of each of the amplitude waves; repeat all the steps of pressurizing to obtain the curve until the pressure applied is higher than the average arterial pressure (MAP) of the object-a predetermined value, and the obtained These curves are sufficient to draw an oscillometric envelop curve by curve fi 11 ing; and to determine the systolic and diastolic pressure according to the pulsatile envelop curve. 2. The blood pressure measurement method according to item 1 of the scope of patent application, wherein the obtained curve includes at least a rising curve, a curve with extreme values, and a falling curve drawn with the amplitude as the vertical axis. 3. The blood pressure measurement method as described in item 2 of the scope of patent application, wherein the average arterial pressure is a maximum value determined by the extreme curve. 4 The blood pressure as described in item 3 of the scope of patent application The measuring method, wherein the predetermined value is 20 to 40 mmHg. 5. A blood pressure measuring device, which is based on the pulsation generated by the arteries of an object. Page 15 r 891 No. 89117855 6. Patent application for measuring blood pressure, at least one of which is inflatable and pressurized, and one controller, which enables the thin bag to be detected by force higher than one of the object. A detector for each pressure transmitter at different pressure values, a signal; a processor for obtaining a pulsation envelope curve and a calculator based on each section of the release curve, and a calculator, according to Xinshu Pressure. 6. If the patent application scope curve contains at least one section with an extreme value of # 7, if the patent application scope the average arterial pressure is the 8th, if the patent application scope the predetermined value is 20 ~ 40mmH includes: A bag; a motor provides power to control the internal pressure of the thin bag to be gradually increased and released until the thin bag inflation pressure is equal to the average arterial pressure (MAP)-a predetermined value; the thin bag is detected in each artery during each stage of pressure release The pulsation produced by the back pressure; connected to the thin bag to convert the pulsation to a voltage to process the voltage signal to form a series of amplitude wave pressures. The curve of each of the amplitude wave peaks connected to one is sufficient to be plotted by curve fitting (osci1lometric envelop ); Use this pulsation envelope curve to determine the depressurization of the heart and the width of 5 items as vertical lines and 6 items · extreme values 7 items g. The blood pressure measuring device described above, wherein the axis has a section of a rising curve and a section of a falling curve. The blood pressure measuring device described above, wherein the curve determines a maximum value. The blood pressure measuring device described above, wherein the 11 1 ΙϋϋΙΙ 丽园 丨 11 1 Painting__ 圆 画 11 1 National IB Hidden Spirit Calendar Painting Page 16 2001.07. 26. 006