TW421587B - Disposable article having bodily waste component sensor - Google Patents

Disposable article having bodily waste component sensor Download PDF

Info

Publication number
TW421587B
TW421587B TW088110980A TW88110980A TW421587B TW 421587 B TW421587 B TW 421587B TW 088110980 A TW088110980 A TW 088110980A TW 88110980 A TW88110980 A TW 88110980A TW 421587 B TW421587 B TW 421587B
Authority
TW
Taiwan
Prior art keywords
disposable
scope
patent application
item
biosensor
Prior art date
Application number
TW088110980A
Other languages
Chinese (zh)
Inventor
Donald Carroll Roe
Andreas Muscat
Yury Igorevich Fedosov
Mikhail Leonidovich Kruchinin
Oleg Nikolaevich Khomiakov
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/107,561 external-priority patent/US6149636A/en
Priority claimed from US09/106,225 external-priority patent/US6186991B1/en
Priority claimed from EP98120476A external-priority patent/EP0997125A1/en
Priority claimed from US09/299,399 external-priority patent/US6713660B1/en
Application filed by Procter & Gamble filed Critical Procter & Gamble
Application granted granted Critical
Publication of TW421587B publication Critical patent/TW421587B/en

Links

Classifications

    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The present invention is directed to a disposable article that comprises a sensor adapted to detect one or more specific biological, health and/or nutrition markers in the wearer's feces. The article may also signal the caretaker, the wearer, or an actuator of the occurrence.

Description

421 587 經濟部智慧財產局員工消費合作社印製 A7 B7 五、發明說明(1 ) 發明領域 本發明有關一種可抛棄物件,且特別是有關一種具有可 偵測人體廢棄物中爲生物及/或其他生物分子之生物辨識 元件及/或適於偵測及/或測量可作爲健康及/或營養指標 之排泄物成分之感測器之可拋棄物件。 發明背景 現今之可拋棄物件如尿片、成人尿失禁墊片、衛生棉及 棉球已廣泛用於嬰兒及剛學走路幼兒之照顧及尿失禁成人 之照顧上’作爲包含、隔離及拋棄人體廢棄物之手段。該 等物件由於其便利性及可靠性,通常取代可再使用且可洗 滌之衣物内褲’作爲該等應用之較佳手段。可拋棄物件藉 吸收或包含沉積在物件上之人體廢棄物而反應排泄、排尿 或排放事件。有些可拋棄物件亦在發生排泄、排尿或排放 事件發生後發出訊號(如溼度指示劑、溫度改變偵測)。本 技藝已知之其他可拋棄吸收物件包括化學反應方式以偵測 穿戴者廢棄物如尿液中之各種物質如pH或離子。然而, 該等均無法特定地偵測標的潛在之致病原微生物如細菌、 病毒、眞菌及寄生蟲(如原蟲)及/或相關生物分子,其均 需要高度選擇性(亦即特異性)及對純化學藥劑之感應性。 再者’該等均無法偵測穿戴者廢棄物中爲潛在健康論點及 /或營養狀態之標記功能之化學成分,此外,物件無法預 測大約將發生健康或營養相關事件且在臨床觀察病徵發生 前對穿戴者或看護者發出預防或治療作用之訊號。 發明概述 -4- 本紙張尺度適用中园國家標準(CNS;IA4規格(210x297公釐) - -- - - ------ 裂------ - 訂---------線 (請先間讀背面之注意爹項声寫本頁) d21 587 ,·, A7 —--—-----------B7_____ 五、發明說明(2 ) 本發月有關種適用於穿戴者之可抛棄物件,包括:包 含至V冑生物辨識元件之生物感測器,生物感測器適於 制人體廢棄物中或穿戴者皮膚上之標的生物分析物。二 種適用於穿戴者之可拋棄物件,包括:適於偵測人體廢棄 物中或穿戴者皮膚上之健康標記或營養標記之感測器。 J式簡單説明 圖1爲依據本發明製得之物件成完全展開狀態之平面 圖,其部分結構經剖面以更清楚顯示物件結構,其中物件 爲尿片。 圖2顯不活化前呈壓縮狀態之本發明人體廢棄物隔離裝 置之透視圖。 圖2Α顯示沿著圖2之2八_2厶線之剖面圖。 圖3 Α顯不具有單一閥値之本發明不連續反應系統之理想 輸出函數。 圖3 Β顯示具有多個閥値之本發明不連績反應系統之理想 輸出函數。 圖4Α顯示本發明不連續反應系統之例舉輸出函數及輸出 函數之第一、第二及第三衍生値。 經濟部智慧財產局員工消費合作杜印製 圖4 Β顯示具有一系列具等時間常數之第一即遲滯之控制 系統之傳送函數。 圖5 Α及5 Β顯示包含電感測凝膠之本發明反應系統具體 例。 圖όΑ ' 6B及6 C顯示包含電感測凝膠之本發明反應系統 另一具體例。 -5- 本紙張尺度適用中國國家標準(CNS)A4規格(2]〇 X 297公釐) 經濟部中央標準局貝工消費合作社印製 a d \ ^ 〇 / ---- 第8811〇98〇號專利申請案 A7 (^年#月才日{女正 中文說明書修正頁(89年8月) B7 _ 五、發明説明(3 ) 圖7為本發明廢棄物袋具體例之透視圖。 圖8為包含廢棄物袋之吸收物件透視圖。 元件符號說明 20 尿片 62腰際 22 底部 90促動器 24 液體滲透上層 91壓差裝置 26 液體不滲透底層 94壓縮彈性材料 28 吸收核心 96空隙空間 30 側片 100長中心線 32 彈性腿摺邊 110側中心線 34 彈性腰部特徵 111廢棄物袋 36 第一腰部區域 112凸緣 37 分叉區域 120尿片 38 第二腰部區域 121 開口 40 固定系統 124上層 45 表面 485觸點 50 縱向緣 494電感應凝膠片 52 端緣 594電感應凝膠 60 感測器 595長方形格柵圖形 發明詳細說明 本文所用之“吸收物件”表示可吸收並包含人體排出物之 裝置,更特別是表示置於或鄰接於穿戴者身體以吸收並包 -6- 本紙張尺度適用中國國家標準(CNS ) A4規格(2丨Ο X M7公釐) ΐ^iT\ (請先閲讀背面之注意事項再填寫本頁) 421587 第8811〇980號專利申請案 中文說明書修正頁(89年8月) A7 B7421 587 Printed by the Consumers ’Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs A7 B7 V. Description of the Invention (1) Field of the Invention The present invention relates to a disposable object, and in particular to a biological and / or other object that has detectable human waste. Biomolecular biometric elements and / or disposables suitable for sensors that detect and / or measure excrement components that can be used as health and / or nutrition indicators. BACKGROUND OF THE INVENTION Today's disposable objects such as diapers, adult urinary incontinence pads, tampons and cotton balls have been widely used in the care of infants and toddlers who have just learned to walk and the care of adults with urinary incontinence as containment, isolation and disposal of human waste. Means of things. Due to their convenience and reliability, these items often replace reusable and washable underwear 'as a better means for such applications. Disposable objects respond to the event of excretion, urination, or discharge by absorbing or containing human waste deposited on the object. Some disposables also signal after an excretion, urination or discharge event (eg humidity indicator, temperature change detection). Other disposable absorbent articles known in the art include chemical reactions to detect various substances such as pH or ions in wearer waste such as urine. However, these are not able to specifically detect the target potential pathogenic microorganisms such as bacteria, viruses, roundworms and parasites (such as protozoa) and / or related biomolecules, all of which need to be highly selective (ie specific ) And sensitivity to pure chemicals. Moreover, none of these can detect the chemical composition of the wearer's waste as a marker of potential health issues and / or nutritional status. In addition, the object cannot predict that a health or nutrition-related event will occur approximately before clinical observation of symptoms Signals wearer or caregiver a preventative or therapeutic effect. Summary of the invention -4- The paper size is applicable to the China National Standard (CNS; IA4 specification (210x297 mm))--------- ------------- Order --------- --Line (please read the note on the back first to write this page) d21 587 , ·, A7 —————----------- B7_____ V. Description of the invention (2) This month The relevant types of disposable objects suitable for wearers include: biosensors containing V 至 biometric elements, and the biosensors are suitable for making target biological analytes in human waste or on the wearer's skin. Disposable items suitable for wearers include: sensors suitable for detecting health marks or nutrition marks in human waste or on the wearer's skin. J-type brief description Figure 1 is an object made according to the present invention. The plan view of the fully expanded state, part of the structure is shown in section to more clearly show the structure of the object, in which the object is a diaper. Figure 2 shows a perspective view of the human waste isolation device of the present invention in a compressed state before being inactivated. Fig. 2 is a sectional view taken along the line 2-8_2. Fig. 3 A shows the discontinuous reaction system of the present invention without a single valve. Figure 3B shows the ideal output function of the non-continuous reaction system of the present invention with multiple valves. Figure 4A shows the example output function and the first and second output functions of the discontinuous reaction system of the present invention. And the third derivative. The consumer cooperation of the Intellectual Property Bureau of the Ministry of Economic Affairs, Du printed Figure 4B shows the transfer function of a first control system with a series of time constants, ie, hysteresis. A specific example of the reaction system of the present invention for gels. Figures 6A and 6C show another specific example of the reaction system of the present invention including an inductive measurement gel. -5- This paper size is applicable to the Chinese National Standard (CNS) A4 specification (2 ] 〇X 297 mm) printed ad \ ^ 〇 / ---- Patent Application No. 8811〇9880 by the Central Standards Bureau of the Ministry of Economic Affairs A7 (^ 年 # 月 才 日 {Corporate Chinese Manual Amendment Page (August 89) B7 _ V. Description of the invention (3) Figure 7 is a perspective view of a specific example of a waste bag of the present invention. Figure 8 is a perspective view of an absorbent article containing a waste bag. Description of component symbols 20 Diapers 62 Waist 22 bottom 90 Device 24 Liquid penetrating upper layer 91 Pressure difference device 26 Liquid impermeable bottom layer 94 Compressing elastic material 28 Absorbing core 96 Void space 30 Side panel 100 long center line 32 Elastic leg hem 110 Side center line 34 Elastic waist feature 111 Waste bag 36 No. One waist region 112 flange 37 bifurcation region 120 diaper 38 second waist region 121 opening 40 fixing system 124 upper layer 45 surface 485 contact 50 longitudinal edge 494 electrical induction gel sheet 52 end edge 594 electrical induction gel 60 sensing 595 Rectangular grille graphic invention detailed description As used herein, "absorbent article" means a device that can absorb and contain human body waste, and more particularly means placed on or adjacent to the wearer's body to absorb and wrap -6- This paper is applicable to this standard Chinese National Standard (CNS) A4 specification (2 丨 〇 X M7 mm) ΐ ^ iT \ (Please read the precautions on the back before filling out this page) 421587 No. 8811〇980 Chinese Specification Correction Page (1989) August) A7 B7

年β月% I1· 3a 五、發明説明( 含由身體排出之各種排出物之裝置。本文中“可拋棄,,係用 以描述通常不|望洗務或者再儲存或再使用作為吸收物件 之吸收物件(亦及其在單次使用後即丟棄,且較好以環境 可相容方式回收、堆肥或處理)。(本文中“處理,,用以表示 尿片之元件於特定地方或位置與尿片其他元件形成(結合 或定位)單一結構或形成結合至尿片另一元件之個別元 件。本文中”結合”包含藉由直接將元件附接至其他元件而 使元件直接固定在另一元件之結構及將元件附接至中間元 件上接著再附接至其他元件而使元件間接固定至另一元件 之結構)。‘‘單一 ”吸收物件表示個別部分組合在一起形成 協調整體部分而不需要另外之操作部分如另外之固定物及 襯裡之吸收物件。本發明吸收物件之較佳具體例為單一可 掘棄吸收物件如圖1所示之尿片20。本文中“尿片,,表示通 常由嬰兒及尿失禁成人穿戴在下部軀幹之吸收物件。本發 明亦可用於其他吸收及非吸收物件如尿失禁塾片、尿失禁 内褲、吸收插入物、尿片固定物及觀裡、可据棄床整、用 於天然或人造肛門之結腸切開術型袋子、女性衛生衣物、 ί帛球、手帕、可拋棄毛巾、面紙、圍兜 '吸水性物件、吸 油性物件、溢出清洗袋、乾燥袋 '可拋棄拖把、箱帶、可 装-- (讀先閱讀背面之注意事項再填寫本頁) 經濟部中央標準局貝工消費合作社印製 6a- 本紙張尺度適用中國國家標準(CNS) A4規格(2IOXN7公釐) 經濟部智慧財產局員工消費合作社印製 421587 A7 ----—________ B7 _______ 五、發明說明(4 ) 抛棄醫藥衣物、可拋棄板及杯子、可拋棄食品製備物及切 割表面、/ct療膝趙、支撑物、可抛棄加熱替等。 圖1爲本發明之尿片2〇之平面圖,其於此圖中顯示爲呈 全面展開狀態之尿片’其部分結構經切開以更清楚顯示尿 片20之架構。尿冇2〇面向穿戴者之部分朝向觀圖者。如 圖1所示,尿片20較好包括液體滲透上層24 ;液體不滲透 底層26 ;吸收核心28 ,其較好置於至少部分之上層以及 底層2 6又間;側片3 0 ;彈性腿摺邊3 2 ;彈性腰部特徵 34;及通常表示爲40之固定系統。尿片2〇示於圖ι而具有 第一腰部區域36,相對於該第一腰部區域36之第二腰部 區域3 8及置於第一腰部區域及第二腰部區域間之分又區域 37。尿片20週邊由尿片20外緣所界定,其中縱向邊緣5〇 通常平行於尿片2 0之長中心線丨〇〇及端緣5 2通常平行於尿 片2 0之側中心線11 〇。 尿片20之底部22包括尿片2〇之主體。底部22包括至少 部分之吸收核心28及較好包含該上層24及底層26之外覆 蓋層。若吸收if勿件包括另外之固定物及襯裡,則底部通常 包括該固定物及襯裡。(例如,固定物可包括亦或多層可 形成物件外覆蓋物之物質且襯裡包括吸收裝配物,其包含 上層、底層及吸收核心。此例中,固定物及/或襯裡可包 含在使用期間用以將襯裡固定就位之固定元件)。對單— 吸收物件而言,底部2 2包括尿片之主結構並加有其他特徵 以形成複雜之尿片結構。雖然上層2 4、底層2 6及吸收核 心2 8可裝配成各種悉知結構,但較佳之尿片結構通常述於 本紙張尺度適用中國國家標準(CNS)A4規格(210X 297公爱) 丨-I------ - --------訂.-------- (請先閱讀背面』之注意爹項,k寫本頁) 42 158 A7 B7 五、發明說明(Year β month% I1 · 3a V. Description of the invention (including various discharge devices discharged from the body. In this article, "disposable," is used to describe generally not | Washing or restoring or reusing as an absorbent article Absorbent articles (and also discarded after a single use, and preferably recycled, composted, or disposed of in an environmentally compatible manner). (In this context, "disposal" is used to indicate that the components of a diaper are in a particular place or location and The other elements of the diaper form (bond or locate) a single structure or form individual elements that are bonded to another element of the diaper. "Combined" herein includes fixing an element directly to another element by directly attaching the element to another element Structure and a structure in which a component is attached to an intermediate component and then attached to another component to indirectly fix the component to another component.) A "single" absorbent object means that the individual parts are grouped together to form a coherent whole without the need for The other operation parts are other fixed articles and lining absorbent articles. A preferred specific example of the absorbent article of the present invention is a single disposable absorbent article, as shown in Figure 1. The diaper 20 shown herein. The term "diaper" herein refers to an absorbent article usually worn on the lower torso by infants and adults with urinary incontinence. The present invention can also be used for other absorbent and non-absorbent articles such as urinary incontinence tablets, urinary incontinence underwear , Absorptive inserts, diaper fixtures and watchers, disposable beds, colostomy bags for natural or artificial anus, feminine hygiene clothing, balls, handkerchiefs, disposable towels, tissues, The 'water-absorbent articles, oil-absorbent articles, overflow cleaning bags, dry bags' can be discarded mops, boxes, and can be installed-(read the precautions on the back before filling this page) Printed 6a- This paper size applies to Chinese National Standard (CNS) A4 specifications (2IOXN7 mm) Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs 421587 A7 ----—________ B7 _______ 5. Description of the invention (4) Discard medicine Clothing, disposable plates and cups, disposable food preparations and cutting surfaces, / ct knee pads, supports, disposable heating pads, etc. Figure 1 is a plan view of the diaper 20 of the present invention, The figure shows the diaper in a fully expanded state. Its partial structure has been cut open to more clearly show the structure of the diaper 20. The part of the diaper 20 facing the wearer faces the viewer. As shown in FIG. 1, the diaper 20 preferably includes a liquid-permeable upper layer 24; a liquid-impermeable bottom layer 26; an absorbent core 28, which is preferably placed on at least a portion of the upper layer and the bottom layer 26; side panels 3 0; elastic leg folds 3 2; elastic waist characteristics 34; and a fixing system generally indicated as 40. The diaper 20 is shown in the figure and has a first waist region 36, a second waist region 38 opposite the first waist region 36, and a first waist region and The division between the second waist region and the region 37. The periphery of the diaper 20 is defined by the outer edge of the diaper 20, wherein the longitudinal edge 50 is generally parallel to the long centerline of the diaper 20 and the end edge 52 is generally parallel On the side of the diaper 20 is the center line 11 〇. The bottom 22 of the diaper 20 includes a main body of the diaper 20. The bottom 22 includes at least a portion of the absorbent core 28 and preferably a cover layer other than the top layer 24 and the bottom layer 26. If the absorbent element does not include additional fixtures and linings, the bottom usually includes the fixtures and linings. (For example, the fixture may include or may form multiple layers of an outer covering of the article and the liner includes an absorbent assembly that includes an upper layer, a bottom layer, and an absorbent core. In this example, the fixture and / or liner may be included during use. To hold the lining in place). For single-absorbent articles, the bottom 22 includes the main structure of the diaper and adds other features to form a complex diaper structure. Although the upper layer 2 4, the lower layer 2 6 and the absorbing core 2 8 can be assembled into a variety of known structures, the better diaper structure is usually described in this paper standard applicable to the Chinese National Standard (CNS) A4 specification (210X 297 public love) 丨- I --------------- Order .-------- (Please read the note on the back first, k write this page) 42 158 A7 B7 V. Description of the invention (

Kenneth B. Buell於 1975年 1 月 1 4 日發證之 USP 3,860,003標 題爲“可拋棄尿片之可收縮側部Buell於1992年9月9日 發證之USP 5,151,〇92 ;及Buell於1993年6月22日發證之 USP 5,221,274 ;及Roe等人於1996年9月10日發證之 1^? 5,554,145標題爲“具有多區結構似彈性膜幅可伸展腰 部特徵之吸收物件”;Buell等人於1996年10月29日發證之 USP 5,5 69,234標題爲“抛棄拉開内褲”;Nease等人於1996 年12月3曰發證之USP 5,580,41 1標題爲“製造吸收物件側 片之零碎片方法,及Robles等人於1997年8月20日申請之 美國專利申請案第08/915,471標題爲“具多方向可伸展側片 之吸收物件”,各揭示均併於本文供參考。 底層26通常爲尿片20鄰置於吸收核心28之面向衣物之 表面45而可避免其内吸收併包含之排出物弄髒可與尿片 20接觸之物件,如床單及貼身衣物。底層26可藉本技藝 悉知之任何附接方式連接至底層2 4、吸收核心2 8或尿片 20之任何其他元件。適宜之底層膜包含由泰瑞豪特in之USP 3,860,003 issued by Kenneth B. Buell on January 14, 1975, entitled "Contractable Sides of Disposable Diapers Buell USP 5,151, 〇92 issued on September 9, 1992; and Buell USP 5,221,274, issued on June 22, 1993; and 1 ^? 5,554,145, issued by Roe et al. On September 10, 1996, entitled "Absorbent article with a multi-zone structure that resembles an elastic film web with stretchable waist characteristics" ; USP 5,5 69,234, issued by Buell et al. On October 29, 1996, entitled "Abandoned Underpants"; USP 5,580,41, issued by Nease et al. On December 3, 1996, entitled " A zero-fragment method for manufacturing side panels of absorbent articles, and U.S. Patent Application Serial No. 08 / 915,471 filed by Robles et al. On August 20, 1997 entitled "Absorbent Articles with Multi-Directional Extensible Side Panels", all disclosures are For reference. The bottom layer 26 is usually the garment-facing surface 45 of the diaper 20 adjacent to the absorbent core 28 to prevent the effluent absorbed and contained therein from contaminating objects that can come into contact with the diaper 20, such as bed sheets and undergarments. The bottom layer 26 may be connected to the bottom layer 24, the absorbent core 28 or any other element of the diaper 20 by any attachment means known in the art. Suitable base films include

Tredegar工業公司製造以商品名XI 5306、XI 0962及XI0964 銷售者。其他適宜底層材料包含可透氣物質如編織布、不 織布、複合材料如包膜不織布、及微孔膜如由日本三井東 壓公司製造以商品名稱ESPOIR NO銷售及由海岸城TX之 愛克森化學公司製造以商品名EXXAIRE銷售者;或整片膜 如得自辛辛那提〇H之Clopay公司以HYTREL摻合物 P1 8-3097銷售者。此種可透氣複合材料詳述於e丄杜邦公 司於1995年6月22曰公告之PCT申請號WO 95/16746 ; Curro 本紙張尺度適闬中舀國家標準(CNS)A4規格(210 x 297公釐) 請 先 閱 讀 背 面 之-注 意 項 I k 本 頁 訂 線 經濟部智慧財產局員工消費合作社印製 421587 經濟部智慧財產局員工消費合作社印制π B7 五、發明說明(6 ) 於1999年2月2日發證之USP 5,865,823 ; Dobrin等人於1996 年1 1月5曰發證之USP 5,57丨,096中。該等參考文件併於本 文供參考。 底層26或其任何材料可於一或多方向彈性伸展。—具體 例中’底層2 6可包括結構似彈性膜(“SELF”)幅。結構似彈 性膜幅爲在未另外使用彈性材料時可在縱向方向展現似彈 性行爲之可伸展材料。適用於本發明之SELF幅更詳述於Tredegar Industries manufactures sellers under the trade names XI 5306, XI 0962 and XI0964. Other suitable substrate materials include breathable materials such as woven fabrics, non-woven fabrics, composite materials such as coated non-woven fabrics, and microporous membranes such as those manufactured by Mitsui Toyo Corporation under the trade name ESPOIR NO and sold by Exxon Chemical Company of Coastal City TX Manufactured under the trade name EXXAIRE; or whole film sold by Clopay, Inc. of Cincinnati, HYTREL Blend P1 8-3097. This breathable composite material is described in detail in PCT Application No. WO 95/16746 published by e6DuPont on June 22, 1995; Curro This paper is suitable for National Standard (CNS) A4 (210 x 297) (%) Please read the back-note I k on this page. Printed on the page of the Intellectual Property Bureau of the Ministry of Economic Affairs, printed by the Consumer Cooperative Cooperative 421587 Printed by the Ministry of Economic Affairs, Intellectual Property Bureau of the Consumer Consumption Cooperative, π B7 V. Description of Invention (6) In 1999 2 USP 5,865,823 issued on May 2; USP 5,57 丨, 096 issued by Dobrin et al. On November 5, 1996. These references are incorporated herein by reference. The bottom layer 26 or any of its materials can be elastically stretched in one or more directions. — In the specific example, the 'bottom layer 2 6' may include a structural elastic-like membrane ("SELF") web. The structure-like elastic film web is a stretchable material that exhibits elastic-like behavior in the longitudinal direction when no elastic material is additionally used. The SELF pattern suitable for the present invention is described in more detail in

Chappell等人於1996年5月21日發證之USP 5,518,801標題 爲“展現似彈性行爲之幅材料”中,其並於本文供參考。另 一具體例中,底層2 6可包括彈性膜、發泡體、股或該等或 其他材料與不織布或合成膜之組合物。 上層24爲柔順、具柔軟感及對穿戴者皮膚無刺激性。適 立上層2 4可由廣泛材料製得如多孔發泡體;網狀發泡體: 穿孔塑膠膜;或天然纖維(如木材或棉纖維)、合成纖維 (如聚酯或聚丙晞纖维)或天然及合成纖維組合之織布或不 織布幅。若上層包含纖維,該纖維可爲紡織黏結、梳毛 者、濕平舖者、溶融吹塑、氫糾結或本技藝已知之其他加 工者。包括原料長度聚丙烯纖維之適宜上層24係由麻薩諸 塞州瓦坡之國際紙業公司分公司Veratec工業製造以商品名 P-8銷售者。 適宜形成之薄膜上層述於Thompson於1975年12月30曰發 澄之USP 3,929,1 3 5標題爲“具漸尖毛細管之吸收結構,,; Mullane等人於1 982年4月1 3日發證之USP 4 324 246標題爲 ‘‘具抗張上層之可拋棄吸收物件”;Radel等人於1982年8月 9- 本紙5長又度適用中0國家標準(CNS)A4規格(21^1^釐) J ^--------^---------線 ί請先閱讀背面V注意^項尹4寫本頁) 經濟部智慧財產局員工消費合作社印 421587 A7 ___________B7_____ 五、發明說明(7 ) 3日發證之USP 4,342,3 14標題爲“展現似纖維性質之彈性塑 膠幅” ;Ahr等人於1984年7月3 1日發證之USP 4,463,045標 題爲“展現非光澤可見表面及似布觸感之微觀可膨脹三維 塑膠幅及Baird於1991年4月9日發證之USP 5,006,394標 題爲“多層聚合膜’’。其他適宜之上層30係依據Curro等 人分別於1986年9月2日及1986年12月16日發證之 USP’s 4,609,5 1 8及4,629,643般製造,兩者均併於本文供參 考°此種形成膜由俄玄俄州辛辛那提之Procter及Gamble公 司以“DRI-WEAVE”提供及由印第安那州泰瑞豪特之 Tredegar公司以 “CLIFF-T”提供。 較好上層2 4係由疏水性材料所構成或處理成疏水性以隔 離穿戴者皮膚與吸收核心28所含之液體。若上層24係由 疏水性材料所製得,則較好上層2 4至少上表面經處理成親 水性使液體更快速移經上層。上層2 4可藉以界面活性劑處 理或併入界面活性劑於上層中而賦予親水性。以界面活性 劑處理上層2 4之適宜方法包含以界面活性劑噴霧上層2 4 並將材料浸於界面活性劑中。此處理及親水性更詳述於 1^1$111§等人於1991年1月29日發證之1]8? 4,988,344標題爲 “具多層吸收層之吸收物件”及Reising等人於丨991年i月29 日發if之USP 4,988,345標題爲“具快速吸納核心之吸收物 件於上層中併入界面活性劑之有些適宜方法更詳述於 Aziz等人於1997年7月1日公告之美國法規發明註册號 H1670中。各參考文獻併於本文供參考。 上層24任何部分可以本技藝悉知之乳液塗佈。適宜乳液 -10 - 本紙張尺度適用中园g家標準(CNS)A4規格(210 X 297公釐) J—lf;------------------ ^ t - ---- ― I (請先閱讀背面V注意穸項声;·寫本頁) 經濟部智慧財產局員工消費合作杜印製 421587 五、發明說明(8 ) 實例己含述於RGe則997年3月4日發證之usp 5,術,⑽標 題爲“具有含软化劑及多元醇聚酯固定劑之乳液化上層 乙可拋棄吸收物件”;尺⑼於””年3月】i日發證之 USP 5,609,5 87標題爲“具有含液體多元醇聚酯軟化劑及固 定劑之乳液上層之尿片”;Roe等人於1997年6月3曰發證 之USP 5,63 5,191標題爲“具有含聚矽氧烷軟化劑之乳液化 上層之尿片”;及尺〇6等人於1997年7月1曰發證之 USP 5,643’588標題爲‘‘具有乳液化上層之尿片,’。乳液可單 獨作用或與其他試劑组合使用如上述之疏水性處理。上層 亦可包含或以抗菌劑處理,其有些實例揭示於Theresa Johnsor^bPS年 9 月 14 日公告之PCT公告號 w〇 95/24173 方示題爲‘上層中含有抗菌劑供臭味控制之吸收物件,,。再 者’上層24、底層26或上層或底層任何部分可雕花及/或 糾結以提供更似布料之外觀。 上層24及底層26可藉本技藝已知之附接方式彼此結 合、結合至尿片2 0之吸收核心2 8或任何其他元件。例 如’附接方式可包含黏著劑之均勻連續層、黏著劑之圖形 層、或個別線、螺紋或點狀黏著劑排列。或者,附接方式 可包括熱鍵結、加壓鍵結、超音波鍵結、動力機械鍵結、 或任何其他適宜附接方式或該等附接方式之組合,如本技 藝悉知者。 吸收核心28可包括通常爲可壓縮、舒適及對穿戴者皮膚 無刺激性且可吸收並留住液體如尿液及其他某些身體排出 物之任何吸收材料。吸收核心2 8可製成廣泛種類之大小及 -11 - 本紙張尺度適用中國國家標準(CNS)A4規格(2】〇χ297公釐) -J ^ 裝--------訂---------線 (請先閱讀背面.之注意Ϋ-項尹i.寫本頁) A7 B7Chappell et al., USP 5,518,801, issued May 21, 1996, is entitled "Materials Showing Web-like Behavior" and is incorporated herein by reference. In another specific example, the bottom layer 26 may include an elastic film, a foam, a strand, or a combination of these or other materials with a non-woven fabric or a synthetic film. The upper layer 24 is compliant, soft and non-irritating to the wearer's skin. The suitable upper layer 2 4 can be made from a wide range of materials such as porous foam; reticulated foam: perforated plastic film; or natural fibers (such as wood or cotton fibers), synthetic fibers (such as polyester or polypropylene fibers) or Woven or non-woven webs of natural and synthetic fibres. If the upper layer contains fibers, the fibers may be textile bonded, carded, wet-laid, melt blow molded, hydrogen entangled, or other processors known in the art. A suitable upper layer 24 including raw length polypropylene fibers is manufactured by Veratec Industries, a division of International Paper Corporation of Wapo, Mass., Under the trade name P-8. A suitable upper layer of the film is described in USP 3,929,1 35, issued by Thompson on December 30, 1975, entitled "Absorption Structures with Tapered Capillaries," issued by Mullane et al. On April 13, 1982 USP 4 324 246 titled "Disposable Absorbent Articles with Tensioned Upper Layers"; Radel et al., August 9, 1982-This paper is 5 long and applicable to the China National Standard (CNS) A4 Specification (21 ^ 1 ^ Li) J ^ -------- ^ --------- line ί Please read the V on the back first ^ Yin Yin4 Write this page) Printed by the Intellectual Property Bureau of the Ministry of Economic Affairs and Consumer Cooperatives 421587 A7 ___________B7_____ V. Description of the invention (7) USP 4,342,3 14 issued on the 3rd is entitled "Elastic Plastic Webs Showing Fibrous Properties"; USP 4,463,045 issued on July 31, 1984 is entitled " A microscopic expandable three-dimensional plastic web exhibiting a non-gloss visible surface and a cloth-like feel, and USP 5,006,394 issued by Baird on April 9, 1991, entitled "Multilayer Polymeric Film". Other suitable upper layers 30 are manufactured according to USP's 4,609,5 1 8 and 4,629,643 issued by Curro et al. On September 2, 1986 and December 16, 1986, respectively, both of which are incorporated herein by reference. The formation film was provided by Procter and Gamble of Cincinnati, Russia as "DRI-WEAVE" and by Tredegar Company of Terre Haute, Indiana as "CLIFF-T". Preferably, the upper layer 24 is composed of a hydrophobic material or is treated to be hydrophobic to isolate the wearer's skin from the liquid contained in the absorbent core 28. If the upper layer 24 is made of a hydrophobic material, it is preferred that at least the upper surface of the upper layer 24 be treated to be hydrophilic so that the liquid moves more quickly through the upper layer. The upper layer 2 4 can be rendered hydrophilic by the surfactant treatment or by incorporating the surfactant in the upper layer. A suitable method of treating the upper layer 24 with a surfactant comprises spraying the upper layer 24 with a surfactant and immersing the material in the surfactant. This treatment and hydrophilicity are described in more detail in 1 ^ 1 $ 111§1 et al., Issued on January 29, 1991 1] 8? 4,988,344 entitled "Absorbent Articles with Multilayer Absorptivity Layers" and Reising et al. In 991 USP 4,988,345, which was issued on January 29th, entitled "Some suitable methods for incorporating absorbent articles with a fast-absorbing core in the upper layer to incorporate surfactants, are described in more detail in the US Regulation Invention published by Aziz et al. on July 1, 1997 Registration No. H1670. Each reference is hereby incorporated by reference. Any part of the upper layer 24 can be coated with emulsions known in the art. Suitable emulsions -10-This paper size is suitable for Zhongyuan Standard (CNS) A4 (210 X 297) Mm) J—lf; ------------------ ^ t----- ― I (please read the note on the back V first; write this page) Employees' cooperation of Intellectual Property Bureau of the Ministry of Economic Affairs printed 421587 V. Description of invention (8) The example has been described in the USP 5, issued by RGe on March 4, 997. The title is "with softener and multiple Emulsified upper layer of alcohol-polyester fixing agent can dispose of absorbent articles "; ruler" "March of the year" USP 5,609,5 87 issued on the i-title is entitled " Diapers with upper layers of emulsions containing liquid polyol polyester softeners and fixatives "; USP 5,63 5,191 issued by Roe et al. On June 3, 1997 entitled" Softening with polysiloxane Diapers with emulsified upper layers "; and USP 5,643'588 issued by July 06, 1997, entitled" Diapers with emulsified upper layers, ". The emulsion can be used alone or in combination with Other reagents are used in combination with the hydrophobic treatment as described above. The upper layer can also contain or be treated with antibacterial agents, some examples of which are disclosed in Theresa Johnsor ^ bPC PCT Bulletin No. w095 / 24173 published on September 14, 2009. The upper layer contains absorbent articles for anti-odor control, and, furthermore, 'the upper layer 24, the bottom layer 26, or any part of the upper layer or the bottom layer may be carved and / or tangled to provide a more cloth-like appearance. The upper layer 24 and the bottom layer 26 may The attachment methods known in the art are combined with each other, the absorbent core 28 or any other element of the diaper 20. For example, the 'attachment method may include a uniform continuous layer of adhesive, a graphic layer of adhesive, or individual lines, Arrangement of thread or dot adhesive. Alternatively, the attachment means may include hot bonding, pressure bonding, ultrasonic bonding, power mechanical bonding, or any other suitable attachment method or combination of these attachment methods, as known in the art. The core 28 may include any absorbent material that is generally compressible, comfortable, non-irritating to the wearer's skin, and absorbs and retains liquids such as urine and certain other body exudates. The absorbent core 28 can be made into a wide variety of Size and -11-This paper size applies to China National Standard (CNS) A4 specification (2) 0 × 297 mm) -J ^ Packing -------- Order --------- Line (Please First read the back. Note 项-Xiang Yin i. Write this page) A7 B7

421587 五、發明說明(9 ) 形狀(如長方形、鐘漏形、《Τ”形、不對稱形等)且可包括 廣泛種類之慣用於可抛棄尿片及其他吸收物件如粉碎木毁 (其通常稱爲空氣氈)之液體吸收材料。其他適宜吸收材料 實例包含皺紗纖維填塞物;熔融吹塑聚合物包含共形成 物;化學強化、改質或交聯之纖維素纖維;薄織物包含薄 披蓋物及薄層合物;悉收發泡體:吸收海綿;超吸收聚合 物•·吸收膠凝材料;或任何其他已知之吸收材料或該材料 之組合。 吸收核心2 8之組態及構成亦可變(如吸收核心或其他吸 收結構可具有可變厚度區、親水性梯度、超吸收梯度、或 較低之平均密度及較低之平均基重吸納區;或可包括一或 多層或結構)。 使用作爲吸收核心之吸收結構實例揭示於We ism an等人 於丨986年9月9日發證之USP 4,610,678標題爲“高密度 吸收結構’’ ;Weisman等人於1987年6月16日發證之 USP 4,673,402標題爲“具多層核心之吸收物件”;Alemany 等人於1989年5月30日發證之USP 4,834,735標題爲“具較 低密度及較低之平均基重吸納區之高密度吸收元件”; Angstadt於1989年1 2月1 9日發證之USP 4,888,231標題爲 “具撒粉層之吸收核心” ;Herron等人於1992年8月1 1日發 證之USP 5,1 37,537標題爲“含個別化聚羧酸交聯之木漿纖 維素纖維之吸收結構”;Young等人於1992年9月1 5曰發證 之USP 5,147,345標題爲“尿失禁處理之高效吸收物件”; Roe於1994年8月30日發證之USP 5,342,33 8標題爲“低黏度 -12- 本紙張尺度適用令國國家標準(CNS)A4規格(210 X 297公釐) -JI — ΪΓ!·裝! — 訂·! * 線 (請先閱讀背面·之注意篆項尹 < 寫本頁)421587 V. Description of the invention (9) The shape (such as rectangular, bell-shaped, "T" shape, asymmetrical shape, etc.) and can include a wide variety of conventionally used disposable diapers and other absorbent objects such as crushed wood (which is usually Liquid absorbent material called air felt). Other examples of suitable absorbent materials include crepe fiber fillers; melt blown polymers include coforms; chemically strengthened, modified or crosslinked cellulose fibers; thin fabrics containing thin drapes Covers and thin laminates; Received foam: Absorbent sponges; Superabsorbent polymers • Absorbent gelling materials; or any other known absorbent material or combination of materials. The configuration and composition of the absorbent core 28 can also be (Eg, the absorbent core or other absorbent structure may have variable thickness regions, hydrophilic gradients, superabsorption gradients, or lower average density and lower average basis weight absorption regions; or may include one or more layers or structures). An example of the use of an absorbent structure as an absorbent core is disclosed in Weisman et al., USP 4,610,678, issued September 9, 986, entitled "High-Density Absorbent Structures"; Weisman et al. USP 4,673,402, issued on June 16, 1987, is titled "Absorbing Articles with Multilayer Cores"; USP 4,834,735, issued by Alemany et al. On May 30, 1989, is titled "With Lower Density and Lower Average Base" High-density absorbing elements in the reabsorption zone "; USP 4,888,231 issued by Angstadt on December 19, 1989 entitled" Absorbing core with dusting layer "; Herron et al. Issued a certificate on August 11, 1992 USP 5,1 37,537 is entitled "Absorption Structure of Wood Pulp Cellulose Fibers Containing Individualized Polycarboxylic Acid Crosslinks"; USP 5,147,345, issued by Young et al. On September 15, 1992, is entitled "Urine Incontinence Treatment "Efficient absorbent articles"; USP 5,342,33 8 issued by Roe on August 30, 1994, entitled "Low Viscosity -12-This paper applies the national standard (CNS) A4 specification (210 X 297 mm) -JI — ΪΓ! · 装! — Ordered !! * Thread (please read the note on the back first, and note 篆 Item Yin & write this page)

經濟部智慧財產局員工消費合作社印*''VJ 421587 經濟部智慧財產局員工消費合作杜印鉍 A7 五、發明說明(1〇 ) 排泄物之可拋棄吸收物件,,;DesMarais等人於1993年1 i月 9曰發證之USP 5,260,345標題爲“水性體液之吸收發泡材料 及含該材料之吸收物件”;Dyer等人於1995年2月7日發證 之USP 5,387,207標題爲“水性體液之濕時仍薄之吸收發泡 材料及其製法”;及DesMarais等人於1 997年7月22日發證 之USP 5,625^22標述爲''由具有非常高水對油比例之高内 相乳液所製得之供水性流體用之吸收發泡材料,,。該等專 利均併於本文供參考。 尿片2 0可包括至少一個有助於提供改良合宜性及遏止性 之彈性腰部特徵3 4。彈性腰部特徵3 4較好自吸收核心2 8 之至少個腰際62故向向外延伸且通常形成物件2〇之至 少邵分端緣5 2。可拋棄尿片經常架構成具有兩個彈性腰部 特徵,一個位於第一腰邵區域3 6中及一個位於第二腰部區 域3 8。再者,雖然彈性腰部特徵3 4或其任何構成元件可 包括一或多個固定至物件2 〇個別成分,彈性腰部特徵3 4 可架構成擴張至物件20其他成分如底層26、上層24或底 層26及上層24兩者。 彈性腰部特徵3 4可架構成述種不同組態包含述於Kievit等 人於1 985年5月7日發證之USP 4,5 1 5,595 : Lash於1 987年1 2 月1日發澄之USP 4,710,189 : Buell於1992年9月9日發證 之USP 5, 151 ,092 :及Buell於1993年6月22日發證之 USP 5,221,274。其他適宜之腰部组態可包含腰布套特徵如 述於Robertson於1991年6月2 5日發證之USP 5,026,364及 Foreman於1989年3月2 8日發證之usp 4 816 〇25。所有上 各纸張尺度適用中囤國家標準(CNS)A-l (210 X 29? 裝--------訂---------線 f請先閱讀背面.之>i意>項#寫本頁) 經濟部智慧財產局員工消費合作钍印製 421587 A7 - B/ ..一 五、發明說明(u) 述參考文獻併於本文供參考。 尿片2 0亦可包含固定系統4 〇。固定系統40包括帶狀帶及/ 或勾及環固定成分,但任何其他已知之固定手段一般可接 受。有些例舉之固定系統揭示於Bueu於1974年1 1月1 9曰 發證之USP 3,M8,594標題爲“可拋棄尿片之膠帶 固定系統” ;Hirotsu等人於1987年5月5日發證之 USP B1 4,662,875標題爲“吸收物件” ;Scripps於1989年7月 11日發證之USP 4,846,815標題爲“具改良固定裝置之 可拋棄尿片” :Nestegard於1990年1月16日發證之 USP 4,894,060標題爲“具改良勾狀固定物部分之克抛棄尿 片’’ :Battrell於1990年δ月7曰發證之DSP 4,946,527標題爲 、、感壓型黏著固定物及其製法,’;及本文前述參考之Bueu於 1 992年9月9日發證之USP 5,151,092 :及Buell於1993年6月 2 2日發證之USP 5,22 1,274。固定系統亦可提供將物件固定 於可拋棄狀態之手段如揭示於R〇bertson等人於1990年1〇 月1 6日發證之USP 4,963,140者。該等專利各併於本文供參 考。另一具體例中,衣物相反侧可經縫合或密接形成内 褲。此可使物件作爲穿戴型尿片如訓練用内褲。 尿片2 0亦可包括側片3 〇。此側片3 0可具彈性或可伸展 以藉先舒適地使尿片20配合至穿戴者且當尿片2〇負載有 排泄物時由於彈性之側片30使尿片2〇側邊伸展並伸縮而 使其在整個穿戴期間保持適性而提供更舒適且更適於輪廓 之舒適感。 雖然本發明尿片20較好具有置於第二腰部區域38中之側 -14- ----- --------------裝--- t請先閱讀背面•之注意Ϋ·項#人寫本頁) ^OJ· ;線 42l587Printed by the Consumers ’Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs * '' VJ 421587 Consumption Cooperation of the Employees of the Intellectual Property Bureau of the Ministry of Economic Affairs by Du Yin Bi A7 V. Description of the Invention (1) Disposable absorbent articles of excreta; 1 The USP 5,260,345 issued on January 9 is entitled "Absorbable foamed material for aqueous body fluids and absorbent articles containing the same"; USP 5,387,207, issued on February 7, 1995, is entitled "Aqueous Body Fluids Absorptive foam materials and methods of making them that are still thin when wet "; and USP 5,625 ^ 22 issued by DesMarais et al. On July 22, 1997, labelled` `by a high internal phase with a very high water-to-oil ratio Absorbent foaming material for water-supply fluid prepared by emulsion. These patents are incorporated herein by reference. The diaper 20 may include at least one elastic waist feature 34 that helps provide improved suitability and containment. The elastic waist feature 3 4 preferably extends outwardly from at least one waist 62 of the absorbent core 2 8 and usually forms at least the edge 5 2 of the object 20. Disposable diapers are often constructed with two elastic waist features, one in the first waist region 36 and one in the second waist region 38. Furthermore, although the elastic waist feature 34 or any of its constituent elements may include one or more individual components fixed to the article 20, the elastic waist feature 34 may be constructed to expand to other components of the article 20 such as the bottom layer 26, the upper layer 24, or the bottom layer 26 and upper 24. Elastic waist features 3 4 can be framed and described in various configurations including USP 4,5 1 5,595 issued by Kievit et al. On May 7, 1985: Lash issued on February 1, 1987 USP 4,710,189: USP 5,151,092 issued by Buell on September 9, 1992: and USP 5,221,274, issued by Buell on June 22, 1993. Other suitable waist configurations may include waist cover features as described in USP 5,026,364 issued by Robertson on June 25, 1991 and usp 4 816 025 issued by Foreman on March 28, 1989. For all paper sizes, the national standard (CNS) Al (210 X 29?) Is installed .-------- Order --------- line f, please read the back first. Of > i I > item # write this page) Consumption Co-operation of Employees of Intellectual Property Bureau, Ministry of Economic Affairs, prints 421587 A7-B / .. V. Description of the Invention (u) References are cited and incorporated herein by reference. The diaper 20 may also include a fixation system 40. The fixing system 40 includes a band and / or hook and loop fixing component, but any other known fixing means is generally acceptable. Some exemplary fixing systems are disclosed in USP 3, M8,594 issued by Bueu on November 19, 1974, entitled "Disposable Nappy Tape Fixing System"; Hirotsu et al. May 5, 1987 Issued USP B1 4,662,875 entitled "Absorbing Articles"; Scripps issued USP 4,846,815 on July 11, 1989 entitled "Disposable Diapers with Improved Fixtures": Nestegard issued a certificate on January 16, 1990 USP 4,894,060 titled "gram disposable diapers with improved hook-shaped fixture part": DSP 4,946,527 issued by Battrell on July 7, 1990 titled ", pressure-sensitive adhesive fixtures and methods for making them,"; And USP 5,151,092 issued on September 9, 1992 by Bueu and the aforementioned references in this article: and USP 5,22 1,274 issued by Buell on June 22, 1993. Fixed systems are also available Means fixed in the disposable state are disclosed in USP 4,963,140 issued by Robertson et al. On October 16, 1990. Each of these patents is incorporated herein by reference. In another specific example, clothing The opposite side can be stitched or tightly formed into underwear. This allows the article to be used as a wearable diaper Such as training underwear. Diapers 20 can also include side panels 30. This side panel 30 can be elastic or stretchable to fit the diaper 20 to the wearer comfortably when the diaper 20 is loaded with During excretion, the elastic side panel 30 expands and contracts the side of the diaper 20 to keep it fit during the entire wearing period, thereby providing a more comfortable and contoured comfort. Although the diaper 20 of the present invention preferably has Place on the side of the second waist area 38 -14------ -------------- Outfit --- t Please read the back first • NoteΫItem # 人 写(This page) ^ OJ;; line 42l587

經濟部智慧財產局員工消費合作社印製 五、發明說明(12 ) 片30,⑽片20可設有置於第一腰部區域36或第一腰部 區域3 6及第二腰部區域3 8兩者中之側片3 〇。側片3 〇可架 構成任何適宜之組態…具彈性側片之尿片實例揭示於 Wood等人於1989年8月15 g發證之usp 4 85 7 〇67標題爲 “具皺摺耳翼之可拋棄尿片” ;Sciaraffa等人於1983年5月3 日發證之USP 4,381,781 ; Van Gompel等人於1990年7月3日 發證之USP 4,938,753 ;本文前述參考之Buei丨於〗992年9月 9日發證之USP 5,151,092 ;及Buells1993年6月22日發 ί登之USP 5,221,274 ; La Von於1997年9月23日發證之 USP 5,669,897標題爲“提供持續動態配適性之吸收物件”; Robles等人於1997年8月20 EJ申請之美國專利申請號 08/915,471 &amp;:題爲具多方向可伸展側片之吸收物件”;各 均併於本文供參考。 床片20較好亦包含可提供液體及其他人體排出物之改良 包含性之腿部摺邊3 2。腿部摺邊亦可稱爲腿部繫帶、惻 翼、障壁摺邊或彈性摺邊^ USP 3,860,003描述一種可提供 具有侧翼及一或多個彈性元件之可收縮腿部開口以提供彈 性腿部摺邊(襯墊摺邊)之可抛棄尿片。Aziz等人分別於 1989年2月28日及1990年3月20日發證之USP 4,808,178及 4,909,803描述具有“站立”彈性翼(障壁摺邊)而可改良腿部 區域之包容之可抛棄尿片。Lawson分別於1987年9月22日 及1989年1月3日發證之USP 4,695,278及4,795,454描述具有 雙重摺邊(包含襯墊摺邊及障壁摺邊)之可抛棄尿片。有些 具體例中,需以如上述之乳液處理所有或部分腿部摺邊。 -15- 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) -------------I ' — — — — — 1— ^ -----III· {靖先閱讀背面之注音^►項声_、寫本頁) 421587 A7B7 五、發明說明(13 本發明具體例亦可包含供收納及包含廢棄物之袋狀物、 提供廢棄物芏隙之空間、限制廢棄物於物件内移動之障 壁'接收及包含尿片中之廢棄物之隔室或空隙等'或其任 何組合。用於吸收物件之袋狀物及空間實例述於R〇e等人 於1996年5月7日發證之USP 5,514,121標題爲“具逐出空 間之尿片” ;Dreier等人於1992年12月15日發證之 USP 5,171,236標題爲“具核心空間之可抛棄吸收物件”; Dreier於1995年3月1 4 EI發證之USP 5,397,3 18標題爲“具袋 狀摺邊之吸收物件,Dreier於1996年7月30曰發證之 1^? 5,540,67 1標題爲‘‘具凸頂袋狀摺邊之吸收物件”;及 1993年1 2月3曰公告之PCT申請案WO 93/25 172標題爲“用 於衛生吸收物件之空間及具有此空間之可拋棄吸收物 件”;及Free land於1994年4月26日發證之USP 5,306,266標 題爲“用於可抛棄吸收物件之可撓性空間” ^隔室或空隙實 例述於Khan於1990年1丨月6日發證之USP 4,968,312標題爲 “可拋棄排泄物隔室尿片”;Freeland於〗991年2月5日發證 之USP 4,990,147標題爲“具有彈性襯裡供隔離廢棄物之吸 收物件” :Holt等人於1991年1 1月5日發證之USP 5,62,840 標題爲“可抛棄尿片”;及Freeland等人於1993年1 2月1 4 EJ 發證之USP 5,269,755標題爲“用於可拋棄吸收物件之三段 上層及含此三段上層之可拋棄吸收物件”。適宜之橫向 障壁實例述於Dreier等人於1996年9月10日發證之 USP 5,554,142標題爲“具多效高橫向分配之吸收物件”; Freeland等人於1994年7月7日公告之:PCT專利W0 94/14395 -16- 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) 請 先 閱 讀. 背 面 之· 注 意 事— 項 1 i 頁 訂 經濟部智慧財產局員工消費合作社印*1^ 421587 A7 B7 經濟部智慧財產局具Η消費合作社印製 五、發明說明(14) 標題爲“具向上站立橫向分配之吸收物件”;及R〇e等人於 1997年8月5日發證之USP 5,653,703標題爲《具角度向上站 立橫向分配之吸收物件”。所有上述參考文獻均併於本文 供參考。 本發明具體例亦可包含廢棄物處理裝置丨1〇如圖7所示。 廢棄物處理裝置!1〇可包含廢棄物袋】】〗以收集排泄物、尿 液或兩者。廢棄物袋丨u可具有開口 12丨及圍繞開口之凸緣 112供較好黏著附接至穿戴者會陰區域。再者,廢 理裝置m已發現在與衣物、或尿片且較可抛棄尿片合^ 時特別有用且有利。包含廢棄物袋u丨之尿片120之—實例 適於圖8。若與尿片12〇或其他衣物連用,則廢棄物袋Hi 可置於或結合至物件之任何表面上。—具體例中 袋111結合至尿片120之上層124。 棄 ^棄物袋111較好爲供收納排出之排泄物或尿液之可撓 性合益。因此’廢棄物袋i i 1較好爲液體不滲透但爲透氣 者再者,廢棄物袋111設計爲具充分強度以耐—般之穿 戴狀況如坐下。 丄棄:袋可包括一或多層…具體例中,廢棄物袋 ^ 一層,較好一薄膜及兩不織布層。袋材料層可 包括任何材料’較好使得袋爲液體不渗透者。本發明較佳 具體例中’可由不織布層及薄膜形成層合物。 任何薄膜層之適宜薄膜材料較好包括熱塑性材料。飫塑 性材料可爲蒸氣可滲透或 … — 令边·^不滲透且可選自所有種類之巷 融黏著劑、聚缔烴尤Α是臂 ' '、疋聚乙% '聚丙烯、非晶形聚烯烴 本紙張尺度·巾關家標 — II ^ ^ · I------- (請先閱讀背面之注意’項声i.寫本頁) -17- A7 42 1 58 7 __B7_ 五、發明說明(15 ) 等;含可熔融成分包括纖維或聚合黏合劑包含天然纖維如 纖維素木漿 '棉花、黃麻、麻之材料;合成纖維如纖維玻 璃、嫘縈、聚酯、聚烯烴、丙缔酸、聚醯胺、芳醯胺、聚 四氟乙烯金屬、聚醯亞胺:黏合劑如雙成分高溶融/低熔 融聚合物、共聚物聚酯、聚氣乙晞、聚乙酸乙晞酯/聚氯 乙烯共聚物、共聚物聚醯胺、包括其中有些構成材料爲非 可熔融之摻合物材料;空氣及蒸氣可滲透材料包含微孔膜 如上述有關底層所述者及整體可透氣材料如杜邦公司所提 供之HYTRELtm及法國ELF Atochem所提供之PebaxTM。 廢棄物袋1丨1可具任何形狀或大小〇較佳之形狀包含平 環形袋、罐形袋、圓錐罐形袋及金字塔形或圓錐金字塔形 袋及平T形袋。再者,廢棄物袋111可由單片材料或多數個 別片材料(其可相同或不同且可在其個別邊緣密封)所提 供。 廢棄物袋111亦可含有吸收材料。吸收材料可包括可吸 收及留住液體之任何吸收材料。吸收衬料可包括慣用於可 拋棄尿片及其他吸收物件之廣泛種類之吸收液體材料。有 些實例述於與吸收核心有關之説明中。 廢棄物袋111設有開口 121因而在儲存於袋孔之前接收排 泄物或尿液。開孔121較好圍繞有凸緣π 2且可提供成任何 形狀或大小如圓形、橢圓形、心形且可爲對稱或不對稱, 較好開口在縱向或橫向之一具有橢圓組態。凸緣可包括後 計成適合穿戴者會陰、顎及/或尾骸骨之突起。 凸緣112需由柔軟、可撓及展性之材料所製得以易於使 -18- 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) 42158? 經濟部智慧財產局員工消費合作社印製 排 及 任 A7 五、發明說明(16 ) 凸緣U2置於會陰或尾骸股。典型材料包含不織布材料、 織布 '開孔熱塑性發泡體、閉孔熱塑性發泡體、開孔發泡 體與拉伸不織布所形成之複合物及薄膜。 廢棄物袋111較好X包括,结合或附接裝置以使裝置固定 至穿戴者身上。此種裝置可包括皮繩及,或塗至廢棄物袋 111面向穿戴者之部份或凸緣之人體可相容黏著劑。任何 皮膚可接受之耐水性感壓型黏著劑可用以將裝置附接至穿 戴者會陰或尾骸骨區域,如水膠體黏著劑及水凝膠黏著 劑。提供所需黏著性質以將凸緣固定至穿戴者敏感之會陰 區域皮膚但仍可相對無痛地應用及移除之特別有效黏著劑 係由交聯聚合物與增塑劑所形成而形成三維基質。 物件20亦較好包含至少一個適於偵測人體廢棄物中一或 多種健康及/或營養標記且具有提供該偵測訊號至穿戴 者、看護者或促動器之感測器6 〇。本文中所用之”感測 器”表示用以偵測事件或與事件有關之參數之裝置。與事 件有關之參數爲與系統參考構造内事件之發生有關之任何 可測得之訊號(亦即,由廢棄物、穿戴者或其成分所引起 之訊號)。感測器包含對一或多種特定輸入有反應之任何 東西。感測器可爲化學' 電化學、生化、或生物、機械、 磁性、熱或本技藝已知之其他訊號。本發明物件特別包括 可對穿戴者、看護或促動器提供訊號指示人體廢棄物如 泄物、尿液或月經液中一或多種健康或營養標記之存在 /或濃度之感測器。訊號可爲光學訊號,包含視覺訊號(如 色度計或螢光指示劑)、化學訊號(如Ρ η、酵素活性或 -19 ---I I ! 1--— lit ' 1-----I ^ · ------ ί請先153讀背面之注意事項再:苒本頁) 各紙張尺度適用中關家標準(CN^^2 髮- — 42158? ΑΓ B7 發 致 發 五、發明說明(17 何其他化學物種之改變)或電訊號。 本文所用之“健康標記”及“營養標記,,(如人類排泄物中) 表示可見於廢棄物中之任何元素、化學或生物成分及與穿 戴者健康(如疾病、感染、毒性)相關界定之成分及營養狀 態之間之组合或相i關係(如比例》)。㈣者營養狀態包 含例如代謝效率、營養缺乏、營養吸收或非吸收、食物及 飲食攝取、食物過敏(如對花生)、食物難忍(乳糖難忍)、 結腸細菌生態(如有益細菌如雙歧桿菌及乳桿菌)及總能量 平衡。健康標記包含與各種健康發不如感染、痢疾、胃腸 道壓力或疾病或毒性有關之重金屬(如鉛及汞等)、放射活 性物質(如铯、緦、鈾等)、脂、酵素 '内源性分泌、蛋白 性物質(如管型)、黏液及衛生物(更詳述於後文之生物感 測器)。重金屬尤其是某些開發中國家及開發國家之舊及/ 或較不富裕地區中爲嚴重之健康危害。例如,鉛及求中毒 可因攝取自環境來源(如來自鉛塗料、無執照重工業)而 生且可致命。更普遍,該等及其他重金屬之低量中毒導 導致尤其是孩童之智力及/或生理發展受阻,其可長期 生且對個體持績影響。蛋白性物質如管型(如於尿液中)可 受標的Tamm-Horsfall蛋白質感測。Tanim-Horsfall蛋白 之感測器適宜實例述於USP 5,780,239,其併於本文供 考。對重金屬之適宜感測器及/或用於此感測器之區別 段詳述於 USPs,5,595,635 ; 5,865,972 ; 5,814,205 5,468,3 66,其均併於本文供參考。 營養標記之非限制性實例包含鈣、維他命(如硫胺素 20 本紙張&amp;度適用中國國家標準(CNS)A4規格(210^297公釐) i—lIl·! — ·裝,! β! ί請先閱讀背面之注意r項再 &lt;為本頁) 經濟部智慧財產局員工消費合作社印製 質 參 手 ^-1 4^1587 A7 B7 五、發明說明(18 核黃素、菸酸、生物素'葉酸、泛酸、抗壞血酸'維他命 E等)、電解質(如鈉、j甲、氯、碳酸氫鹽等)、脂、脂肪酸 (長鏈及短鏈)、包(棕櫚酸鈣)、胺基酸、酵素(如乳糖' 殿粉酶、脂酶 '胰酶等)、膽酸及其鹽、類固醇及碳水化 物。例如,鈣非吸收具重要性因其長期引起骨質缺乏。雖 然於成人(尤其是年老婦女)中約吸收之重要性有許多報 導,但認爲對小孩(尤其是嬰孩)亦重要。嬰孩飲食可衝擊 #5吸收且因此衝擊骨質及/或密度。例如已顯示再嬰孩配 方中棕櫚酸在三酸甘油酯之2 -位置(亦即似母乳)改變成j _ 及,或3 -位置(如在有些嬰孩配方中),導致棕櫚酸較少自 三酸甘油酯“主鏈”中斷裂,且因此減少人體吸收此營養。 未斷裂之棕櫚酸於消化道中結合鈣形成皂(亦即棕橺酸鈣) 且於排泄物中離開人體。(此過程詳述於嬰孩疾病檔案 (1997年1 1月)77 F178-F184)。因此排泄物中妈及/或皂含 量爲評估鈣由消化系統吸收之一潛在手段。以Arsenaz〇 III(酸性環境)及甲酚酞複合酮(鹼性環境)爲主之適宜色度 計鈣感測器分別得自M0聖路亦Sigma-Aldrich化學公司之 目錄编號588-3及587-A。鈣之其他例舉感測器及/或可用於 感測器之區別裝置詳述於USPs,5,705,620 ; 5,580,441及 5,496,522中,期均併於本文供參考。 本發明感測器可與載體結構聯合。載體結構可固定、安 定及/或至少部分包封感測器。載體結構實例包含一或多 層織布、不織布、膜、發泡體 '纖維織品、水凝膠等。感 測器可連接至載體結構、固定在兩或多成分、層之間、或 21 參紙張尺度適用中國國豕標準(CNS)A4規格(2】fl X 297公爱) 請 先 閲 讀. 背 面 之 注 意 事-項 # I ‘ 頁 訂 經濟部智慧財產局員工消費合作社印製 421587 A7 ___B7 五、發明說明(19 ) 摺疊載體結構’或可密封在載體結構内。載體結構可視情 況包括黏合劑或皮膚黏結組合物或其他附接手段已固定至 少部分知該載體結構至物件或其成分或穿戴者皮膚上。再 者,至少部分載體可爲水溶性。 經濟部智慧財產局員工消費合作社印製 本發明有些具體例中’感測器6 0可包括生物感測器。本 文中之“生物感測器’’定義爲包刮一或多個適於偵測一或多 種標地致病性微生物或相關生物分子之生物反應性裝置之 成分(如酵素感測器、細胞器感測器、组織感測器、微生 物感測器' 免疫感測器或電化學感測器)。“生物反應性,, 定義爲具有選擇性反應且較好結合本文定義之標的致病性 微生物及/或相關生物分子之能力。通常生物感測器藉提 供特定結合方式而發揮功能且因此偵測標的之生物活性分 析物。就此而言’生物感測器即使存在有許多化學及生物 物體如排泄物之混合物時仍具高度活性。另—方面,與化 學反應方式相關之化學感測器通常不具有高選擇性或生物 感測器之擴增性質且因此無法充分適於偵測生物反應性分 析物,尤其是當其以低濃度及/或以複雜介質如人體磨棄 物存在時。標地生物分析物經常爲包括多數生物及其他成 分之複雜混合物之次要成分。因此,於許多生物感測器應 用中,須偵測標的分析物至每百萬份、每兆份、或甚至更 低量。據此’對生物感測器需要約1〇7_1〇8或更高之區別比 例以辨識複雜混合物中之標的生物分析物。 本發明之生物感測器可包括生物辨識元件或分子辨識元 件’其提供對特定分析物之高度特異結合或偵測選擇性。 -22-本纸張尺度適用中國國家標準(CNS)A4規格(21〇 x 297公釐) 42 158 經濟部智慧財產局員工消費合作社印製 Α7 Β7 五、發明說明(20 ) 生物辨識元件或系統可微生物衍生之材料如酵素或酵素序 列;抗體:膜受體蛋白質;DNA :器官器、天然或合成細 胞膜;完整或部分存活或非存活細菌、植物或動物細胞; 或植物或哺乳類組織物種及通常具有與標的生物分析物特 異反應之功能》生物辨識元件負貴選擇性辨識分析物及提 供輸出訊號基礎之物理化學訊號。 生物感測器可包含生物催化生物感測器及生物親和性感 測器。生物催化感測器具體例中,生物辨識元件爲“生物 依化且可包括酵素、器官器、植物或哺乳類組織物種或 全細胞、選擇性結合位置“翻轉’,(亦即偵測過程中可再使 用)’導致輸入訊號之明顯擴增。生物催化感測器通常可 用於確實時間之連續感測。 生物親和性感測器通常應用至細菌、病毒及毒素且包厶 化學受體爲主之生物感測器及/或免疫學感測器(亦即免疫 感測器)。化學受體爲負責部分對存活有機體以高選擇性 感測其境之化學品之能力之複雜生物分子巨裳配β化學 受體爲主之感測器包刮一或多種天然或合成化學受體以提 供標的生物分析物之存在或濃度訊號(視覺或電訊號)。有 些具體例中’化學受體可與電極(亦及電傳導)連用以提供 可偵測之電訊號。化學受體可包含全部或部分神經束(如 來自觸角或其他感測器官)及/或全或部分天然或合成細胞 膜。另一方面,免疫感測器之生物辨識元件通常爲抗體。 抗體具高度特異性且可對細菌、病毒或微生物之片段做得 (如細菌細胞壁、寄生物卵或其部分)及大生物分予。適宜 -23- 本纸張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) it if —-------裝---I----訂 -----線 (請先閲讀背兩之注意事項寫本頁) 42158 7 - A7 ____________B7______ 五、發明說明(21 ) 抗體可爲單;^或多株。任何例中,± &amp;親和性感測器通常 不可逆’因爲生物感測器知受體位置在暴露治標地生物分 析物時變飽和。 有些具體例中,生物催化性生物感測器可結合例如 RNA/DNA探子或其他高親和性結合系統,其中最初之生 物辨識事件接著將生物擴增訊號。例如,特定細菌可由包 括基因材料如DNA&lt;生物感測器偵測如生物辨識元件及 PCR(亦即聚合酶鏈反應)擴增以偵測少量有機體,較好低 於或等於約500個有機體。生物催化及生物親和性生物感 泪J器詳述於复學聚法期刊,5 10(1990)347-354及Kirk- 技術百K書,第4版(1992),紐約約翰威利 父子公司,其揭示併於本文供參考。 本發明生物感測器較好偵測與逼迫(亦即未來病徵提出) 或現行人體全身疾病狀態有關之生物活性分析物,包含 (但不限於)致病性細菌、寄生蟲(如生命循環任何階段, 包含其卵或部分、胞囊或成熟有機體)、病毒、眞菌如白 色念%菌(Candida albicans)、對致病原之抗體及/或微生物 產生之毒素〇此外’生物感測器可標的與逼迫或現行局部 健康公佈如應力蛋白質(如細胞素)及IL_丨α (介白素^ α )(其可進行皮膚刺激或發炎之臨床現象)有關之生物活 性分析物。較佳具體例中,生物感測器作爲原活性感測器 之功fie· ’在提出臨床病徵之前偵測逼迫狀沉並對穿戴者或 看護發出訊號。此有時間對穿戴者投與預防或治療處理而 若不存在時可明顯減少病徵之嚴重性及持續性。再者,憤 -24- 本紙張尺度这用中园國家標準(CNS)A4規格(210 X 297公釐) I f— ——III I» - - I (請先閱讀背面-之注意旁項#.i.寫本頁) 訂. ί線 經濟部智慧財產局員工消費合作、社印製 A7 B7 五、發明說明(22 ) 測穿袋者人體廢棄物(如#泄物)中標第生物分析物之存在 ------:---------裝—— (請先閱讀背面·之注意t項#4寫本頁) 之感測器60可偵測與感測器接觸表面如皮膚之殘留污染並 提供適宜訊號。 -線. 由生物辨ΐ战元件A生之物理&lt;匕學訊冑可由穿戴者或看護 看出(亦即經由肉眼觀察顏色變化)β其他具體例可產生光 學訊號其可需要其他儀器以增強訊號。其包含登光、生物 發光、全部内反射共振 '表面電漿共振、Raman*法及其 他雷射爲主之方法。例舉之表面電漿共朕生物感測汽油德 國MUenster之XanTec分析系統公司提供之IBIS 1及汨13 π, 其可包括生物共軛之表面作爲生物辨識元件,或者,訊號 可經由例如可產生電訊號(如電流、電位、傳導性或遲滞) 之伴隨傳導器進行,其可展現(如於讀取器上如LED或LCD 顯示器)或制約可聽或接觸(如擺動)訊號或可制約本文之 促動器。此訊號可定性(如指示標的生物分析之存在)或定 量(如標的生物分析物之量或濃度指標)。此具體例中,傳 導器視情況產生光學、熱或聽覺訊號。 經濟部智慧財產局員工消費合作社印製 任何例中,訊號亦可持久(如通常在至少與物件使用壽 命相同時限之長時間内仍安定且可讀取)或暫時(亦即登記 確實時間測量)。此外,訊號可傳導至遠處之指示位置(亦 即經由線圈或傳導器,如遠紅外線或rf傳導器)指示在物 件中或上或遠處裝置上之其他部位。再者,感測器6〇或其 任何成分適於偵測及/或僅發出高於既定閥値之標的生物 分析物濃度之訊號(如其中標的生物分析物正常存在於人 體廢棄物中或分析物濃度低於已知“危險値”)。 -25- 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) 經濟部智慧財產局員工消費合作社印製 4 2 1 5 8 7 A7 ---------- 五、發明說明(23 ) 如上所述,本發明生物感測器適於偵測之標的分析物可 爲致病微生物如於人體胃腸道中有關之致病微生物,尤其 是產生痢疾者。此類致病原對追蹤每年因痢疾疾病嚴重生 病或死π &amp;孩童數目尤其重要。已發現嚴重慢性例即可導 致體重減輕及永久生理及精神發展阻礙。感測器6〇可偵測 之致病細菌之非限制性實例包含大腸埃希氏菌(Escherichia coli)( 貝稱爲E,Coh);沙門氏菌,包含傷寒沙門氏菌(s typhi)、副傷寒沙門氏菌(s paratyphi)、腸炎沙門氏菌 (S.entedditis)、鼠傷寒沙門氏菌(s typhimurium)及海德爾 堡沙門氏菌(S,heidelberg);志賀氏菌如索氏志贺氏菌 (Shigella sonnei) ' 弗氏志賀氏菌(shigella flexneri)、鲍氏 志賀氏菌(Shigella boydii)及痢疾志賀氏菌(shigella dysenteriae);霍亂弧菌(Vibrio cholerae);結核分歧桿菌 (Mycobacterium tuberculosis);小腸結腸炎耶耳森氏菌 (Yersinia enterocolitica):嗜水氣單胞菌(Aeromonas hydrophila);類志質鄰單胞菌(piesi〇m〇nas shigelloides); 彎曲桿菌如空腸彎曲桿菌(C. jejuni)及大腸桿菌(C. coli); 脆弱擬桿菌(Bacteroides fragilis);及梭菌包含敗毒梭菌(C. septicum)、產氣莢膜梭菌(C_ perfringens)、肉毒梭菌(C. botu丨丨num)及銀難梭菌(C. diffici丨e)。適於偵測E. coli之市 售生物感測器之非限制性實例係購自N C杜漢AndCare工業 之測試套組#4001。置於另一非限制實例,P A雅德利之 ABTHCH科學工業提供“生物分析生物轉導器”,以BB Au-1050.5-FD-X提供,其可藉共價固定多胜肽、酵素 '抗體 -26- 本纸張K度適闬中國國家標準(CNS)A4規格(210 X 297公釐) L-----------—裝--------訂---------線 &lt;請先閱讀背面‘之注意^項#\寫本頁) A7 421587 B7___ 五、發明說明(24 ) 或DNA片段致其表面上而賦予生物特異性(例如本文所述 之微生物或其他標的生物分析物)^其他適宜之微生物生 物感測器述於USP 5,869,272(革蘭式陰性菌): 5,795,717(志賀氏菌);5,83〇 341 ; 5,795,453 ; 5 354,661 ; 5,783,399 ; 5,840,488 ; 5,827,651 ; 5,723,330 及 5,496,700, 其均併於本文供參考。 本發明生物感測器適於偵測之標的分析物亦可爲病毒。 該等可包含誘發痢疾之病毒如輪狀病毒或其他病毒如鼻病 病毒及人類免疫缺乏病毒(HI v) ^適於偵測Η! v之例舉生 物感測器述於上述參考之1^?5,830,341及5,795,453。各該 等專利併於本文供參考。 另一具體例中,本發明生物感測器適於偵測之標的分析 物亦可爲寄生蟲,尤其在其生命循環期間棲息於胃腸道 者。此種寄生蟲可包含原蟲、蛔蟲及其他胃腸道寄生蟲。 可偵測之寄生蟲其他實例包含溶組織内阿米巴(entam〇eba histolyticaK其引起阿米巴痢疾)' 克氏錐蟲(trypana cmziK其引起卻格斯疾病)及惡性瘧原蟲(抑抓灿咖 falciparum) 〇 又一具體例中,本發明生物感測器適於偵測之桿的分析 物亦可爲眞菌如白色念珠菌。除了致病性細菌以外,某種 有益之結腸細菌可被偵測及/或測量作爲健康指授如他歧 桿菌及乳桿菌。 “ 本發明生物感測器適於偵測之標的分析物亦 1 j馬蛋白質 或與皮膚應力有關之抗原。較好該等分析物可在 仕反滑表面 -27- 本紙張尺度適用中國國家標準.(CNS)A4規格(210 X 297公釐) —ϊ I I I--I ' I I----I ^--- ------^ (請先閱讀背面之注意穸項&quot;_寫本頁) 經濟部智慧財產局員工消費合作社印制衣 587 587 經濟部智慧財產局員工消費合作社印製 A7 __________B7______ 五、發明說明(25 &gt; 上偵測到’較好在提出臨床可見之皮膚剌激之前。其可包 含應力蛋白質如細胞素、组胺酸及其他反應因子包含介白 素(如IL-1 a,IL-2,IL·3,IL-4及IL-S)及干擾素(包含干擾 素a及g) ^又,其較好在臨床可見之發紅、刺激或皮膚炎 之如藉感測器6 0偵測。此外,本發明生物感測器適於偵測 酵素或與皮膚刺激(尿布疹)有關之其他生物因子,包含胰 朊酶、胰凝乳蛋白酶及脂酶。 本發明生物感測器亦可包含生物辨識系統,包含酵素或 結合蛋白質如固定在物理化學轉導器表面上之抗體。例如 可經由利用因菌株產生之抗體之生物感測器而偵測特定菌 株或者’可藉對標的細菌之細胞外產物(如菌株如大腸 菌所產生之毒素)特異之生物辨識元件(包含抗體及合成或 天然分子受體)偵測標的細菌。可用以偵測酚(如尿液或排 泄物中)之例舉酵素電極包含以騰脫酶爲主之電極或聚酚 氧化酶酵素電極分別述於j〇seph Wang等人於1997年1 〇月 14曰發證之USP 5,676,820標題爲《遠處電化學感測器”及Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs. 5. Description of the invention (12) A piece 30, the cymbal piece 20 may be provided in either the first waist area 36 or the first waist area 36 and the second waist area 38. The side sheet 3 〇. The side panel 3 can be constructed in any suitable configuration ... An example of a diaper with an elastic side panel is disclosed in Wood et al., August 15th, 1989, 15 g, usp 4 85 7 〇67 entitled "Wrinkled Ear Wings" Disposable diapers "; USP 4,381,781 issued by Sciaraffa et al. On May 3, 1983; USP 4,938,753 issued by Van Gompel et al. On July 3, 1990; Buei 丨 referenced above in this article USP 5,151,092 issued on September 9, 992; and USP 5,221,274 issued by Buells on June 22, 1993; USP 5,669,897 issued by La Von on September 23, 1997 is entitled "Provided Continuously adaptive absorbent article "; U.S. Patent Application No. 08 / 915,471 &amp; filed by Robles et al. On August 20, 1997, entitled" Absorbent article with multi-directional stretchable side panels "; This article is for reference. The bed sheet 20 preferably also includes improved inclusive leg folds that can provide liquids and other human body discharges. 2. The leg folds can also be referred to as leg straps, flaps, and barrier folds. Hem or elastic hem ^ USP 3,860,003 describes a retractable leg opening with side flaps and one or more elastic elements To provide disposable diapers with elastic leg hems (pad hems). USP 4,808,178 and 4,909,803 issued on February 28, 1989 and March 20, 1990, respectively, describe "standing" elasticity Wings (barrier hem) to improve the containment of disposable diapers in the leg area. Lawson USP 4,695,278 and 4,795,454, issued on September 22, 1987 and January 3, 1989, respectively, describe double hem (including Disposable diapers with pad hem and barrier hem. In some specific cases, all or part of the leg hem needs to be treated with the emulsion as described above. -15- This paper size applies to China National Standard (CNS) A4 (210 X 297 mm) ------------- I '— — — — — 1— ^ ----- III · {Jingxian read the note on the back ^ ►Item sound_ 、 (Write this page) 421587 A7B7 V. Description of the invention (13 Specific examples of the present invention may also include bags for storing and containing waste, providing space for waste gaps, barriers to restrict the movement of waste within the object, and receiving and Compartments or voids containing waste in diapers, etc. 'or any combination thereof. Bag-shaped for absorbing articles And space examples are described in USP 5,514,121 issued by Roe et al. On May 7, 1996, entitled "Nappies with Evicted Space"; USP issued by Dreier et al. On December 15, 1992 5,171,236 titled "Disposable absorbent article with core space"; USP 5,397,3 18 issued by Dreier on March 14, 1995 EI issued the title "Absorbent article with bagged hem, Dreier in 1996 1 ^? 5,540,67 1 issued on July 30, 1997, entitled "Absorbent Article with Convex Bag-shaped Folds"; and PCT Application WO 93/25 172, published on February 3, 1993 "A space for sanitary absorbent articles and disposable absorbent articles having such a space"; and USP 5,306,266 issued by Freeland on April 26, 1994, entitled "Flexible space for disposable absorbent articles" ^ Examples of compartments or voids are described in USP 4,968,312 titled "Disposable Fecal Compartment Diapers" issued by Khan on January 6, 1990; Freeland issued USP 4,990,147 titled on February 5, 991 "Absorbent article with elastic lining to isolate waste": USP 5,62, issued by Holt et al. On November 5, 1991 840 entitled “Disposable diapers”; and USP 5,269,755 issued by Freeland et al. On December 14, 1993, EJ, entitled “Three-segment upper layer for disposable absorbent articles and disposables containing this three-segment upper layer” Absorbent objects. " Examples of suitable horizontal barriers are described in USP 5,554,142 entitled "Multi-effect and Highly Horizontally Absorbent Articles" issued by Dreier et al. On September 10, 1996; Freeland et al., Published on July 7, 1994: PCT Patent WO 94/14395 -16- The size of this paper is applicable to Chinese National Standard (CNS) A4 (210 X 297 mm) Please read first. Note on the back-Item 1 i. Print * 1 ^ 421587 A7 B7 Printed by the Intellectual Property Bureau of the Ministry of Economic Affairs and printed by a consumer cooperative V. Description of Invention (14) The title is "Absorbent article with upright and horizontal distribution"; and Roe et al., August 5, 1997 USP 5,653,703, which is issued daily, is entitled "Absorbent articles distributed at an angle and standing upright." All the above references are incorporated herein by reference. Specific examples of the present invention may also include a waste treatment device. Waste disposal device! 10 may include waste bags]] to collect feces, urine or both. The waste bag 丨 u may have an opening 12 丨 and a flange 112 surrounding the opening for better adhesive attachment To the wearer Shade area. Furthermore, the waste disposal device m has been found to be particularly useful and advantageous when combined with clothing, or diapers and more disposable diapers. ^ One of the diapers 120 including a waste bag u 丨-an example is suitable for FIG. 8 If used with diaper 120 or other clothing, the waste bag Hi can be placed or bonded to any surface of the object.-In the specific example, the bag 111 is bonded to the upper layer 124 of the diaper 120. Disposal bag 111 It is preferably a flexible combination for accommodating excretions or urine. Therefore, the 'waste bag ii 1 is preferably liquid impermeable but breathable, and the waste bag 111 is designed to have sufficient strength to resist — General wearing conditions such as sitting down. Disposal: The bag can include one or more layers ... In the specific example, the waste bag ^ one layer, preferably a film and two non-woven layers. The bag material layer can include any material 'better makes the bag It is liquid impervious. In the preferred embodiment of the present invention, a laminate can be formed from a non-woven fabric layer and a film. Suitable film materials for any film layer preferably include thermoplastic materials. The plastic material can be vapor permeable or ... · ^ Impermeable and can be selected from all Alley-type melting adhesives, poly-associated hydrocarbons, especially A ',' polyethylene% ', polypropylene, amorphous polyolefins, paper size, towel family standard — II ^ ^ · I ------- (Please First read the note on the back of the item i. Write this page) -17- A7 42 1 58 7 __B7_ 5. Description of the invention (15), etc .; contains fusible components including fibers or polymer binders containing natural fibers such as cellulose wood pulp 'Cotton, jute, hemp materials; synthetic fibers such as fiberglass, rayon, polyester, polyolefins, acryl, polyamine, aramide, polytetrafluoroethylene, polyimide: binders Such as two-component high-melting / low-melting polymers, copolymer polyesters, polyethylenimide, polyvinyl acetate / polyvinyl chloride copolymers, copolymers of polyamidine, including some of which are non-meltable blends. Air and vapor permeable materials include microporous membranes such as those described above for the underlying layer and overall breathable materials such as HYTRELtm provided by DuPont and PebaxTM provided by ELF Atochem, France. The waste bag 1 丨 1 may have any shape or size. Preferred shapes include flat ring bags, can bags, conical can bags, pyramid or conical pyramid bags, and flat T bags. Furthermore, the waste bag 111 may be provided by a single piece of material or a plurality of individual pieces of material (which may be the same or different and may be sealed at their individual edges). The waste bag 111 may contain an absorbent material. The absorbent material may include any absorbent material that can absorb and retain liquids. Absorbent liners can include a wide variety of liquid-absorbent materials customarily used in disposable diapers and other absorbent articles. Some examples are described in the notes related to the absorption core. The waste bag 111 is provided with an opening 121 so as to receive feces or urine before being stored in the bag hole. The opening 121 is preferably surrounded by the flange π 2 and can be provided in any shape or size such as a circle, an oval, a heart, and may be symmetrical or asymmetrical. It is preferable that the opening has an elliptical configuration in one of the longitudinal and lateral directions. The flange may include protrusions that are counted to fit the wearer's perineum, jaw, and / or tail bone. The flange 112 needs to be made of soft, flexible and malleable materials. -18- This paper size applies to China National Standard (CNS) A4 (210 X 297 mm) 42158? Consumption by employees of the Intellectual Property Bureau of the Ministry of Economic Affairs Cooperative printed platoon and Ren A7 V. Description of the invention (16) Flange U2 is placed on perineal or skeletal stock. Typical materials include non-woven materials, woven 'open-cell thermoplastic foams, closed-cell thermoplastic foams, composites of open-cell foams and stretched nonwovens, and films. The waste bag 111 preferably includes, attaching or attaching a device to secure the device to the wearer. Such a device may include a leather cord and a body-compatible adhesive applied to the portion or flange of the waste bag 111 facing the wearer. Any skin-acceptable, water-resistant, pressure-sensitive adhesive can be used to attach the device to the wearer's perineum or coccygeal bone region, such as hydrocolloid adhesives and hydrogel adhesives. A particularly effective adhesive that provides the required adhesive properties to secure the flange to the skin of the wearer's sensitive perineal area but can still be applied and removed relatively painlessly is a three-dimensional matrix formed from crosslinked polymers and plasticizers . The object 20 also preferably includes at least one sensor 6 suitable for detecting one or more health and / or nutrition markers in human waste and having the detection signal provided to the wearer, caregiver or actuator. As used herein, "sensor" means a device used to detect an event or an event-related parameter. Event-related parameters are any measurable signals related to the occurrence of events in the system's reference structure (ie, signals caused by waste, wearers, or their components). A sensor contains anything that responds to one or more specific inputs. Sensors can be chemical 'electrochemical, biochemical, or biological, mechanical, magnetic, thermal, or other signals known in the art. The articles of the present invention include, in particular, sensors that provide a signal to the wearer, caregiver, or actuator to indicate the presence and / or concentration of one or more health or nutritional markers in human waste such as faeces, urine, or menstrual fluid. The signal can be an optical signal, including a visual signal (such as a colorimeter or a fluorescent indicator), a chemical signal (such as P η, an enzyme activity, or -19 --- II! 1 --— lit '1 ----- I ^ · ------ ί Please read the notes on the back 153 before reading: 苒 This page) Zhongguanjia standard (CN ^^ 2 hair-42158? ΑΓ B7 hair hair) Description (17 changes in other chemical species) or telecommunications. As used herein, "health labels" and "nutrition labels" (such as in human excrement) refer to any element, chemical or biological component found in the waste, and The wearer's health (such as disease, infection, toxicity) is related to the combination or relationship between the defined components and nutritional status (such as ratio). The nutritional status of the wearer includes, for example, metabolic efficiency, nutritional deficiency, nutritional absorption or non-absorption, Food and dietary intake, food allergies (such as peanuts), food intolerance (lactose intolerance), colonic bacterial ecology (such as beneficial bacteria such as Bifidobacterium and Lactobacillus), and total energy balance. Health labels include inferiority to various healthy hair Infection, dysentery, Intestinal pressure or diseases or toxicity related heavy metals (such as lead and mercury), radioactive substances (such as cesium, rubidium, uranium, etc.), lipids, enzymes' endogenous secretions, proteinaceous substances (such as casts), mucus And sanitary products (more on biosensors below). Heavy metals are a serious health hazard especially in some developing countries and old and / or less affluent areas of developing countries. For example, lead and poisoning Can be caused by ingestion from environmental sources (such as from lead paint, unlicensed heavy industry) and can be fatal. More generally, the low levels of poisoning of these and other heavy metals can cause intellectual and / or physical development, especially in children, which can impede It is long-term and affects individual performance. Proteinaceous substances such as casts (such as in urine) can be detected by the target Tamm-Horsfall protein. Suitable examples of Tanim-Horsfall protein sensors are described in USP 5,780,239, which is combined with This article is for your reference. Suitable sensors for heavy metals and / or the differences for this sensor are detailed in USPs, 5,595,635; 5,865,972; 5,814,205 5,468,3 66, all of which are incorporated herein by reference. Non-limiting examples include calcium, vitamins (such as thiamine 20 paper &amp; degree applicable to China National Standard (CNS) A4 specifications (210 ^ 297 mm) i—lIl ·! — · Equipment, β! Ί Please First read the note on the back of the page and then <this page) Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs ^ -1 4 ^ 1587 A7 B7 V. Description of the invention (18 riboflavin, niacin, biotin 'Folic acid, pantothenic acid, ascorbic acid', vitamin E, etc.), electrolytes (such as sodium, methyl chloride, chlorine, bicarbonate, etc.), lipids, fatty acids (long and short chain), packets (calcium palmitate), amino acids, Enzymes (such as lactose 'enzymes, lipases, pancreatic enzymes, etc.), cholic acid and its salts, steroids and carbohydrates. For example, calcium non-absorption is important because it causes bone deficiency over time. Although much has been reported about the importance of absorption in adults (especially older women), it is also considered important for children, especially babies. Baby diet can shock # 5 absorption and therefore impact bone and / or density. For example, it has been shown that palmitic acid changes in the 2-position (ie, breast-like) of triglycerides to j _ and, or 3-position (as in some infant formulas), resulting in less palmitic acid Glycerides break in the "backbone" and thus reduce the body's absorption of this nutrition. Unbroken palmitic acid binds calcium in the digestive tract to form soap (ie, calcium palmitate) and leaves the body in excreta. (This process is detailed in the Archives of Infant Diseases (November 1997) 77 F178-F184). Therefore, maternal and / or soap content in excreta is one of the potential measures to assess the absorption of calcium from the digestive system. Appropriate colorimeter calcium sensors based on Arsenaz〇III (acidic environment) and cresolphthalein compound ketone (alkaline environment) are available from M0 Shengluyi Sigma-Aldrich Chemical Company, catalog numbers 588-3 and 587, respectively. -A. Other examples of calcium sensors and / or differentiating devices that can be used for the sensors are detailed in USPs, 5,705,620; 5,580,441 and 5,496,522, both of which are incorporated herein by reference. The sensor of the invention can be combined with a carrier structure. The carrier structure may fix, stabilize, and / or at least partially encapsulate the sensor. Examples of the carrier structure include one or more layers of woven cloth, non-woven cloth, film, foamed fiber fabric, hydrogel, and the like. The sensor can be connected to the carrier structure, fixed between two or more components, layers, or 21-sheet paper. Applicable to China National Standard (CNS) A4 specifications (2) fl X 297 public love. Please read first. Attention-item # I 'Page order Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs 421587 A7 ___B7 V. Description of the invention (19) Folding carrier structure' may be sealed in the carrier structure. The carrier structure may optionally include an adhesive or a skin adhesion composition or other attachment means that has been fixed to at least a portion of the carrier structure to the object or its components or the wearer's skin. Furthermore, at least part of the carrier may be water-soluble. Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs. In some specific examples of the present invention, the 'sensor 60' may include a biosensor. A "biosensor" is defined herein as a component that covers one or more bioreactive devices (e.g., enzyme sensors, cells) suitable for detecting one or more target pathogenic microorganisms or related biomolecules. Sensor, tissue sensor, microbial sensor (immunity sensor or electrochemical sensor). "Bioreactivity, defined as a pathogenic disease that has a selective response and better incorporates the targets defined herein Sexual microorganisms and / or related biomolecules. Biosensors typically function by providing specific binding means and therefore detect the target biologically active analyte. In this regard, a 'biosensor is highly active even in the presence of a mixture of many chemical and biological objects such as feces. On the other hand, chemical sensors related to chemical reaction methods generally do not have high selectivity or the amplification properties of biosensors and are therefore not sufficiently suitable for detecting bioreactive analytes, especially when they are at low concentrations And / or in the presence of complex media such as human waste. Target biological analytes are often secondary components of complex mixtures that include most organisms and other components. Therefore, in many biosensor applications, target analytes must be detected to parts per million, parts per trillion, or even lower. Accordingly, a differential ratio of about 107-7 or higher is required for the biosensor to identify the target biological analyte in a complex mixture. The biosensor of the present invention may include a biometric or molecular recognition element &apos; which provides a highly specific binding or detection selectivity to a particular analyte. -22- This paper size applies the Chinese National Standard (CNS) A4 specification (21 × 297 mm) 42 158 Printed by the Consumers ’Cooperative of Intellectual Property Bureau of the Ministry of Economic Affairs A7 B7 V. Description of the invention (20) Biometric components or systems Microbial-derived materials such as enzymes or enzyme sequences; antibodies: membrane receptor proteins; DNA: organs, natural or synthetic cell membranes; whole or part of viable or non-viable bacteria, plants or animal cells; or plant or mammalian tissue species and generally It has the function of reacting specifically with the target biological analytes. "Biometric components can be used to selectively identify analytes and provide physical and chemical signals based on the output signal. The biosensor may include a biocatalytic biosensor and a bioaffinity sensor. In a specific example of a biocatalytic sensor, the biometric element is "bio-dependent and may include enzymes, organs, plants or mammalian tissue species or whole cells, and the selective binding position is" flipped ", (that is, it can be Use) 'causes a significant amplification of the input signal. Biocatalytic sensors can often be used for continuous sensing over time. Bio-affinitive sensors are usually applied to bacterial, viral and toxin-containing biosensors and / or immunological sensors (ie, immunosensors) dominated by chemical receptors. Chemical receptors are complex biomolecules that are responsible for part of the ability to detect chemicals in living organisms with a high degree of selectivity to chemicals in the environment. Beta chemical receptor-based sensors cover one or more natural or synthetic chemical receptors. Provide the presence or concentration signal (visual or electrical signal) of the target biological analyte. In some cases, a 'chemical acceptor' can be connected to an electrode (and electrical conduction) to provide a detectable electrical signal. Chemical receptors can include all or part of a nerve bundle (eg, from antennae or other sensing organs) and / or all or part of a natural or synthetic cell membrane. On the other hand, the biological recognition element of the immune sensor is usually an antibody. Antibodies are highly specific and can be made on fragments of bacteria, viruses or microorganisms (such as bacterial cell walls, parasite eggs or parts thereof) and large organisms. Suitable-23- This paper size is applicable to China National Standard (CNS) A4 (210 X 297 mm) it if —------- installation --- I ---- order ----- line (Please read the notes on the back two first and write this page) 42158 7-A7 ____________B7______ 5. Description of the invention (21) The antibody can be single; ^ or multiple strains. In any case, the ± &amp; affinity sensor is usually irreversible 'because the biosensor knows that the receptor position becomes saturated when the target bioanalyte is exposed. In some specific cases, biocatalytic biosensors can be combined with, for example, RNA / DNA probes or other high-affinity binding systems, where the initial biometric event is followed by a biological amplification signal. For example, specific bacteria can be detected by genetic materials such as DNA &lt; biosensors such as biometric elements and PCR (i.e., polymerase chain reaction) amplification to detect a small number of organisms, preferably less than or equal to about 500 organisms. Biocatalysis and Bioaffinity Biosensory Tears are detailed in the Journal of Fuxueju Law, 5 10 (1990) 347-354 and Kirk-Tech 100K, 4th Edition (1992), John Wiley & Sons, New York, It is disclosed and incorporated herein by reference. The biosensor of the present invention can better detect bioactive analytes related to persecution (that is, future symptoms) or the current state of human body disease, including (but not limited to) pathogenic bacteria, parasites (such as any life cycle Stage, including its eggs or parts, cysts or mature organisms), viruses, maggots such as Candida albicans, antibodies to pathogens and / or toxins produced by microorganisms. In addition, 'biosensors may The target is bioactive analytes related to persecution or current local health publications such as stress proteins (such as cytokines) and IL_ 丨 α (interleukin ^ α), which can perform clinical signs of skin irritation or inflammation. In a preferred specific example, the function of the biosensor as the original active sensor is to detect the percussion and send a signal to the wearer or caregiver before clinical symptoms are presented. There is time to administer prophylactic or therapeutic treatments to the wearer, which, if not present, can significantly reduce the severity and persistence of the symptoms. Furthermore, anger-24- this paper size uses the China National Standard (CNS) A4 specification (210 X 297 mm) I f — ——III I »--I (please read the back side-note the next item # .i. Write this page) Order. ί Consumers ’cooperation with the Intellectual Property Bureau of the Ministry of Economic Affairs, printed by the agency A7 B7 V. Description of the invention (22) The human waste (such as ###) in the bag was tested as the biological analyte The existence of ------: --------- installation-(please read the note on the back first, note # 4 to write this page), the sensor 60 can detect the contact with the sensor Residual contamination of the surface such as the skin and provide suitable signals. -Line. Physics & Biometrics from Bio-Analytical Warfare Element A can be seen by the wearer or caregiver (ie, the color change is observed by the naked eye) β Other specific examples can generate optical signals which may require other instruments to enhance Signal. It includes dimmer light, bioluminescence, all internal reflection resonances, surface plasma resonance, Raman * method, and other methods based on lasers. Exemplary surface-plasma-coated biosensing gasoline IBIS 1 and 汨 13 π provided by XanTec Analytical System Company of MUenster, Germany, which may include bio-conjugated surfaces as biometric identification elements, or the signal may be generated by, for example, telecommunications Signal (such as current, potential, conductivity, or hysteresis) with the transmitter, which can be displayed (such as on a reader such as an LED or LCD display) or restrict audible or contact (such as wobble) signals or can restrict the text Of its actuator. This signal can be qualitative (such as the presence of the target biological assay) or quantitative (such as the amount or concentration of the target biological analyte). In this specific example, the transmitter generates optical, thermal, or audible signals as appropriate. In any case printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs, the signal can also be durable (such as usually stable and readable for at least the same time period as the life of the object) or temporary (that is, the actual time of registration is measured) . In addition, the signal can be transmitted to a distant indicated location (ie, via a coil or transmitter, such as a far-infrared or rf transmitter) to indicate in or on the object or elsewhere on the distant device. Furthermore, the sensor 60 or any component thereof is suitable for detecting and / or only sending a signal higher than the target biological analyte concentration of a predetermined threshold (for example, the target biological analyte is normally present in human waste or analyzed Concentration is lower than the known "dangerous radon"). -25- This paper size applies to China National Standard (CNS) A4 (210 X 297 mm) Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs 4 2 1 5 8 7 A7 ---------- 5 2. Description of the invention (23) As mentioned above, the target analyte suitable for detection by the biosensor of the present invention may be a pathogenic microorganism such as a relevant pathogenic microorganism in the human gastrointestinal tract, especially those who have dysentery. Such pathogens are particularly important for tracking the number of children & dysfunctions that die or die each year from dysentery disease. Severe chronic cases have been found to cause weight loss and permanent impediments to physical and mental development. Non-limiting examples of pathogenic bacteria that can be detected by the sensor 60 include Escherichia coli (known as E, Coh); Salmonella, including typhoid, Salmonella paratyphoid ( s paratyphi), S. enteredditis, S. typhimurium, and S. heidelberg; Shigella, such as Shigella sonnei (Shigella sonnei) (Shigella flexneri), Shigella boydii and shigella dysenteriae; Vibrio cholerae; Mycobacterium tuberculosis; Yersinia enterocolitica enterocolitica): Aeromonas hydrophila; piesiomonas shigelloides; Campylobacter such as C. jejuni and E. coli; Bacteroides fragilis; and Clostridium include C. septicum, C_ perfringens, C. botu 丨 num, and Clostridium difficile C. diffici Shu e). A non-limiting example of a commercially available biosensor suitable for detecting E. coli is a test kit # 4001 from NC Du Han AndCare Industries. In another non-limiting example, AB Yardley ’s ABTHCH Scientific Industries provides a “bioanalytical biotransducer”, provided as BB Au-1050.5-FD-X, which can be covalently immobilized with peptides, enzymes' antibodies- 26- The K degree of this paper is suitable for the Chinese National Standard (CNS) A4 (210 X 297 mm) L ------------------------- Order-- ------ line &lt; please read the note on the back ^ item # \ write this page) A7 421587 B7___ V. Description of the invention (24) or DNA fragment on the surface to give biological specificity (such as in this article Microorganisms or other target biological analytes described) ^ Other suitable microbial biosensors are described in USP 5,869,272 (gram-negative bacteria): 5,795,717 (Shigella); 5,83,341; 5,795,453; 5 354,661; 5,783,399 5,840,488; 5,827,651; 5,723,330 and 5,496,700, all of which are incorporated herein by reference. The target analyte suitable for detection by the biosensor of the present invention may also be a virus. These may include dysentery-inducing viruses such as rotavirus or other viruses such as rhinovirus and human immunodeficiency virus (HI v) ^ Suitable for detecting Η! V Examples of biosensors are described in reference 1 above ? 5,830,341 and 5,795,453. Each of these patents is incorporated herein by reference. In another specific example, the target analyte suitable for detection by the biosensor of the present invention may also be a parasite, especially a person who inhabits the gastrointestinal tract during its life cycle. Such parasites can include protozoa, roundworms, and other gastrointestinal parasites. Other examples of detectable parasites include entamoeba histolyticaK (which causes amoebic dysentery) 'trypana cmziK (which causes Chogs disease) and Plasmodium falciparum (suppressive (Calka falciparum) 〇 In another specific example, the analyte suitable for detecting the rod of the biosensor of the present invention may also be a fungus such as Candida albicans. In addition to pathogenic bacteria, certain beneficial colonic bacteria can be detected and / or measured as health indicators such as Bifidobacterium and Lactobacillus. "The target analyte suitable for detection by the biosensor of the present invention is also a horse protein or an antigen related to skin stress. It is better that these analytes can be on the anti-slip surface -27- This paper size applies to Chinese national standards . (CNS) A4 specification (210 X 297 mm) —ϊ II I--I 'I I ---- I ^ --- ------ ^ (Please read the note on the back first &quot; _Writing this page) Printed by the Consumers ’Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs 587 587 Printed by the Consumers’ Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs A7 __________B7______ 5. Description of the Invention (25 &gt; Detected 'Better in clinical Before skin irritation. It may contain stress proteins such as cytokines, histidine and other response factors including interleukins (such as IL-1 a, IL-2, IL · 3, IL-4 and IL-S) and interference (Including interferons a and g) ^ Also, it is better to detect redness, irritation or dermatitis clinically visible by the sensor 60. In addition, the biosensor of the present invention is suitable for detecting enzymes Or other biological factors related to skin irritation (diaper rash), including trypsin, chymotrypsin, and lipase. The sensor may also include a biometric system that includes enzymes or binding proteins such as antibodies immobilized on the surface of a physicochemical transducer. For example, a specific strain may be detected via a biosensor using antibodies produced by a strain or 'may Detection of target bacteria by biometric elements (including antibodies and synthetic or natural molecular receptors) specific to extracellular products of target bacteria (such as toxins produced by strains such as coliform). Can be used to detect phenols (such as urine or excretion) For example, the enzyme electrode includes an electrode mainly composed of Tengde enzyme or a polyphenol oxidase enzyme electrode, which is described in USP 5,676,820 issued by Joseph Wang et al. On October 14, 1997. Electrochemical sensors "and

Anthony P.F. Turner等人於1992年2月2 5日發證之USP 5,09 1,299標題爲“用於有機溶劑之酵素電極,,。其均併於本 文供參考。 若前述任何實例中,可直接偵測或可藉對有機體特異之 毒素、酵素或其他由微生物或抗體產生之蛋白質如單株抗 體結合而偵測特定微生物。適於偵測蛋白溶解酵素之例舉 生物感測器述於USP 5,607,567及毒素述於USP 5,496,452 ; 5,521,101 及5,567,301。 -28- 本紙張尺度適用中國國家標準(CNS)A4規格(210x297公釐) —• — —*1 —----I I · I------訂-------- (請先閱讀背面•之注意&quot;項#欠寫本頁) 經濟部智慧財產局員工消費合作社印5衣 421587 A7 _____B7__ 五、發明說明(26 ) 感測器60可包括一或多個“原活化感測器”。器特別可用 於其中標的生物反應性分析物、健康及/或營養標記之偵 測早於臨床可觀察之健康病徵發生之具體例中。本文中 “原活化感測器”表示可偵測穿戴者身體中或上(亦即皮膚) 或廢棄物(亦即輸入)中之變化或訊號,其直接有關或至少 與逼迫事件或潛在健康或皮膚相關事件有關。原活化感測 器可反應於一或多個上述之輸入。 原活化感測器6 0可偵測逼迫事件或與逼迫事件有關之參 數或最少與逼迫事件發生有關,特別是全身性或皮膚健康 事件或狀況(亦即提出臨床可觀察之指標或病徵)^可藉本 發明原活化感測器6 0偵測或預測之逼迫事件可包含早期階 段之鉛中毒 '早期營養失調及/或因營養非吸收所引起之 維他命缺乏、痢疾疾病、皮膚刺激或發疹(包含念珠菌病) 及/或穿戴者之其他類疾病或醫藥狀況如寄生蟲感染。偵 測之健康、營養標記及/或生物分析物可唯一或多步驟自 確實提出臨床病徵移除。例如,感測器可對上述狀況偵測 潛在前驅物(如可在誘出應力蛋白質且隨後在臨床可見之 皮膚刺激之前之皮膚受排泄物污染)^與事件有關之參數 爲與系統參考結構中事件發生有關之任何可測得之輸入訊 號(亦即由廢棄物或穿戴者所引起之訊號)。例如原活化感 測器60可追蹤排泄物中之白色念珠菌及皮膚上之殘留結腸 菌(亦即偵測殘留污染),其均爲可進行皮膚刺激之訊號。 在其中生物辨識元件不產生易見之訊號(如顏色改變)之 生物感測器具體例中,感測器6 〇可包含與生物辨識元件相 本紙張尺度適用中國囷家標準(CNS)A4規格(210 x 297公釐) I 裝--------訂---------線 (請先閱讀背面_之注意^項ΛΚ寫本頁) 421587 A7 ---------- 五、發明說明(27 ) 通之傳導器,以將生物辨識元件之物化訊號轉化成對穿戴 者、看濩或物件成分(如促動器)之有用訊號。例舉之傳導 器可包含本技藝已知之電化學傳導器(包含電位計、安培 計及導電計傳導器)、光學傳導器(包含榮光 '生物發光、 總内部反射共振及表面卵胞漿遺傳因子共振)、熱傳道器 及聽覺傳導器。電源如小型3伏特手錶電池或印刷薄膜叙 電/也了連接至感測器6 〇以提供任何所須之動力。 本發明之生物感測器效能可藉下述測試方法段落所述之 反應因子測試測量。反應因子描述生物感測器暴露至排泄 物測忒物咸時之反應與生物感測器暴露至生理時鹽水溶液 時之反應比値且可用以評估生物感測器對預期可見於排泄 物之生物活性分析物及對尿液之感應性。本發明之生物感 測器當暴露至每1可生理食鹽水丨克排泄物測試物質之濃度 之排泄測試物質於水溶液中或尿液中時,較好具有至少 2、3或5之反應因子,更好至少1〇且甚至更好至少。 (本文使用生理食鹽水表示背景輸入訊號,其存在於最正 常之環境如含水體液中)。此種生物感測器亦可明顯區別 與對排泄物特異有關之標的生物活性分析物之排泄物存在 與生理食鹽水存在間之差異。 經濟部智慧財產局員工消費合作社印製 偵測排泄物之一方法爲偵測翼臭素(常見於排泄物之物 質)。已發現排泄物中糞臭素濃度每克排泄物約18〇微克而 展液中糞臭素量實質上較低。糞臭素-般爲源自腸系統中 色胺代謝之微生物降解產物。 糞臭素偵測生物感測器之一較佳具體例中,生物感測哭 -30- 本紙張^朝中g g家辟(CNS)A4規格⑵Q χ挪公爱) 經濟部智慧財產局員工消費合作社印製 42l587 A7 ______B7 _ 五、發明說明(Μ ) 包括機因工程之微生物,其同化糞臭素及/或其他物質。 例如可經由同化過程中之氧消耗而測量糞臭素特異物質之 同化。適於偵測糞臭素之微生物包含波梅氏不動桿菌 (Acinetobacter baumannii)TOI36(FERM P-12891,曰本專利 公報JP05304947)及桿菌屬 T〇i41(FErm P-12914,揭示於 日本專利公報JP05304948)。包含此種微生物之適宜生物 感測器例如購自德國 lnstitut fSr Chemo-und Biosensorik of Minster以Mikrobielle Sensoren提供者。 若微生物併入生物感測器中,其可藉本技藝已知之技術 如包含、吸附'交聯'包封、共價附接、其任何組合等固 定於生物感測器中。再者,固定可在許多不同基質(如本 技藝已知者)上進行。某較佳具體例中,固定基質可選自 聚合物爲主之材料、水凝膠、薄紙、不織布材料、織布材 料。 某具體例中,包含任何生物感測器具體例之感測器6 〇可 置於或動作連接至微晶片如矽晶片、MEMs(亦即微電化學 系統)裝置或積體電路上。微晶片爲主之生物感測器稱爲 “生物晶片’’。與感測器種類無關,微晶片可包括數個具有 相同或不同感應性、動力及/或標的分析物(亦即標記)之 感測器成分,其排列適於偵測不同程度或該分析物之組 合。再者’此種排列中各感測器可提供不同型態之訊號, 包含本文揭示者,且可與不同促動器或控制器連用。又此 排列之各感測器可獨立操作或與此排列中之任何數量之其 他感測器聯合使用。 -31 - 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) ---I I ί I I --------^ (請先閱讀背面•之注意旁項声、寫本頁) 421587Anthony PF Turner et al., USP 5,09 1,299, issued on February 25, 1992, entitled "Enzyme Electrodes for Organic Solvents," which are incorporated herein by reference. If any of the foregoing examples are direct, Detection or detection of specific microorganisms by binding to organism-specific toxins, enzymes or other proteins produced by microorganisms or antibodies, such as monoclonal antibodies. Examples of biosensors suitable for detecting proteolytic enzymes are described in USP 5,607,567 And toxins are described in USP 5,496,452; 5,521,101 and 5,567,301. -28- This paper size applies the Chinese National Standard (CNS) A4 specification (210x297 mm) — • — — * 1 —---- II · I --- --- Order -------- (please read the note on the back first &quot; Item #owe to write this page) Printed on the Consumer Consumption Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs 421587 A7 _____B7__ V. Description of Invention (26) The sensor 60 may include one or more "primary activation sensors". The device is particularly useful for detecting the target bioreactive analytes, health and / or nutrition markers before specific occurrences of clinically observable health signs occur Example. "Original activation sensor" Detects changes or signals in or on the wearer's body (ie, skin) or waste (ie, input) that are directly related or at least related to a persecution event or a potential health or skin related event. Original activation sensing The device can respond to one or more of the above inputs. The original activation sensor 60 can detect persecution events or parameters related to persecution events or at least related to the occurrence of persecution events, especially systemic or skin health events or conditions ( That is, clinically observable indicators or symptoms are proposed) ^ The persecution event that can be detected or predicted by the original activation sensor 60 of the present invention may include lead poisoning at an early stage 'early nutritional imbalance and / or caused by non-absorption of nutrients Vitamin deficiency, dysentery disease, skin irritation or rash (including candidiasis) and / or other types of diseases or medical conditions of the wearer such as parasitic infection. Health, nutritional markers and / or biological analytes detected can be unique Or multiple steps to remove the clinical symptoms that are actually proposed. For example, a sensor can detect potential precursors to the conditions described above (such as The skin before the skin irritation on the bed is contaminated with excreta) ^ The parameters related to the event are any measurable input signals related to the occurrence of the event in the system reference structure (ie, signals caused by waste or the wearer) For example, the original activation sensor 60 can track Candida albicans in the feces and residual colonic bacteria on the skin (that is, detect residual pollution), which are signals that can be used for skin irritation. The biometric element does not generate In the specific example of a biosensor with a visible signal (such as a color change), the sensor 6 〇 may contain the same biometric components as the paper size. Applicable to China National Standard (CNS) A4 (210 x 297 mm) I -------- Order --------- line (please read the note on the back _ item ^ K to write this page) 421587 A7 ---------- 5. Description of the invention (27) A conductive device to convert the physical signal of the biometric element into a useful signal for the wearer, watch or object component (such as an actuator). Exemplary transducers may include electrochemical transducers (including potentiometers, ammeters, and conductivity meter transducers), optical transducers (including glory 'bioluminescence, total internal reflection resonance, and surface cytoplasmic genetic factor resonance) known in the art. ), Thermal communicator and auditory transducer. A power source, such as a small 3 volt watch battery or a printed film, is also connected to the sensor 6 to provide any required power. The performance of the biosensor of the present invention can be measured by the response factor test described in the following test method paragraph. The response factor describes the response of the biosensor when it is exposed to fecal matter, and the response of the biosensor when it is exposed to physiological saline solution, and can be used to evaluate the biosensor's response to organisms that are expected to be found in the feces. Active analytes and sensitivity to urine. The biosensor of the present invention preferably has a response factor of at least 2, 3, or 5 when the excretion test substance is exposed to a concentration of 1 g of fecal test substance in physiological saline solution in aqueous solution or urine, Better at least 10 and even better at least. (This paper uses physiological saline as the background input signal, which exists in most normal environments such as aqueous body fluids). Such a biosensor can also clearly distinguish the difference between the presence of excreta in a biologically active analyte that is specifically related to excreta and the presence of physiological saline. Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs. One method of detecting fecal matter is to detect wing odor (common substance in fecal matter). It has been found that the concentration of skatole in fecal matter is about 180 micrograms per gram of faecal matter while the amount of skatole in the effluent is substantially lower. Fecal odorant is generally a microbial degradation product derived from tryptophan metabolism in the intestinal system. In a preferred specific example of a faecal odor detection biosensor, the biosensor cries -30- this paper ^ North Korea gg Jia Pi (CNS) A4 size ⑵ Q χ Norwegian public love) Ministry of Economic Affairs Intellectual Property Bureau Staff Consumer Cooperative Print 42l587 A7 ______B7 _ V. The description of the invention (M) includes microorganisms of mechanistic engineering, their assimilation faeces and / or other substances. For example, the assimilation of skatole-specific substances can be measured by oxygen consumption during the assimilation process. Microorganisms suitable for detecting skatole include Acinetobacter baumannii TOI36 (FERM P-12891, Japanese Patent Gazette JP05304947) and Bacillus Toi41 (FErm P-12914, disclosed in Japanese Patent Gazette JP05304948) . Suitable biosensors containing such microorganisms are, for example, commercially available from lnstitut fSr Chemo-und Biosensorik of Minster, Germany as a Mikrobielle Sensoren provider. If a microorganism is incorporated into the biosensor, it can be fixed in the biosensor by techniques known in the art such as inclusion, adsorption 'cross-linking' encapsulation, covalent attachment, any combination thereof, and the like. Furthermore, fixation can be performed on many different substrates, such as those known in the art. In a preferred embodiment, the fixing substrate may be selected from polymer-based materials, hydrogels, tissue paper, non-woven materials, and woven materials. In a specific example, the sensor 6 including any specific example of a biosensor may be placed or operatively connected to a microchip such as a silicon chip, a MEMs (ie, a microelectrochemical system) device, or a integrated circuit. Microchip-based biosensors are called "biochips." Regardless of the type of sensor, a microchip can include several analytes (ie, tags) with the same or different inductive, dynamic, and / or target properties. The sensor components are arranged in an array suitable for detecting different degrees or combinations of the analytes. Furthermore, each sensor in this arrangement can provide different types of signals, including those disclosed herein, and can be activated with different Sensor or controller. Each sensor in this array can be operated independently or in combination with any number of other sensors in this array. -31-This paper size applies to China National Standard (CNS) A4 (210 X 297 mm) --- II ί II -------- ^ (please read the note on the back side first, write this page) 421587

五、發明說明(29 ) 本發明任何感測器60可置於及/或動作地連接至可抛棄 物件之任何部分’其可暴露至感測器設計用以偵測之輸入 中。就本發明目的而言,“動作地連接”表示通訊裝置使得 感測器6 0在偵測輸入時可對物件2 〇有些 感測器60可與下列分離並動作地連接:感測=二 份、另一感測器60、促動器、控制器或物件2〇之有些其 他部分或成分。“可動作地連接”可包含例如經由導電線圈 或元件、經由傳送訊號如無線頻率、紅外線或其他傳送頻 率通訊之電連接。或者,感測器6〇可經由機械連接如氣體 或水力連接而動作地連接。 經濟部智慧財產局員工消費合作社印製 可拋棄物件具體例(如圖1之尿片2〇)中,感測器6〇可位 於物件20之前腰部區域36 '後腰部區域38或交叉區域3 7 中且可與底座22、上層24、底層26、吸收核心28、側片 30 '腿部摺邊32、腰部特徵34、固定系統4〇 '縱向緣5〇 或端緣52等整體整合' 鄰置於、連接於或包括該等部分。 其中標的生物分析物與人體廢棄物連用之某較佳具體例 中’感測器6 0可置於物件2 0之交又區域以使人體廢棄物 與感測器接觸達最大。其中感測器適於偵測或測量穿戴者 皮膚上之標的生物劑之其他較佳具體例中,感測器6 〇可置 於物件知上層、摺邊、腰部特徵、排泄物接收袋、間隔物 或任何其他邵分’其將在使用過程中與穿戴者皮膚接觸。 某具體例中,感測器亦可在物件中使用乳液或其他護膚组 合物。 感測器6 0可整合至物件2 0或可藉看護者或穿戴者裝 -32- 本紙張尺度適用中0囷家標準(CNS)A4規格(210 X 297公釐) I 58 A7 B7 經濟部智慧財產局員工消費合作社印製 五、發明說明(3〇 ) 設。物件穿戴期間感測器亦可變成至少部分與物件分離且 可附接至穿戴者皮膚。感測器可固定(永久或脱離地)(如 經由如Velcr〇TM或水溶性黏結劑之機械固定系統)至單體結 構’包含膠帶、纖維或合成布、冑蓬鬆物、薄膜、棉織 品、發泡體¥。再者,感測器6〇可完全含於物件如物件 2 0中或可具有位於物件中之接收部分而可與所需輸入及位 於物件内或物件外之其他部分如傳導部分接觸。感測器⑹ 可在物件2 0外部但仍動作連接至物件2 〇之有些部分,使 得感測器6 0可偵測物件外之輸入並對控制器及/或促動器 提供訊號。有些具體例中,感測器可與物件分離如分別經 由黏著劑或本技藝悉知之其他手段應用至穿戴者有些部分 及/或可具有與物件分離之一或多個成分。 有些具體例中,可裝設擦拭裝置或元件以使穿戴者或看 護自感測器充分清潔人體廢棄物,而可藉由視覺評估或讀 取訊號(尤其對設有此訊號之感測器具體例)^擦拭元件可 包含布(纖維或合成)、不織布高蓬鬆物、薄膜、發泡體、 剛性或半剛性似滾軸元件及類似地置於物件中並適於使此 元件用以清潔感測器顯示器。擦拭元件可藉本技藝悉知之 任何已知方式至少固定至鄰近感測器6 0之物件成分如上 層。擦拭裝置可視情況包括水或任何已知清潔助劑以促進 清潔穿戴者或感測器顯示器。 某較佳具體例中,物件2 0亦可包括促動器。本説明書中 所述之“促動器”表示包括“電位”及使電位轉化以進行或活 化“反應功能’’之設備之裝置。促動器之電位可包括儲存或 -33- 本纸張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) —ί -----------裝· I ί ί !訂---------線 (請先閱讀背面'之注意Ϋ·項异 &lt; 寫本頁) 經濟部智慧財產局員工消費合作社印製 4 21 bay A7 ______B7 五、發明說明(31 ) 電位能或儲存物。因此促動器可藉將電位轉化爲動能或藉 輸送儲存物質而進行或活化反應功能。“反應功能”於本^ 明目的定義爲因人體廢棄物、穿栽者或其成分所進行之功 能或對穿戴者或看護發出訊號。人體廢棄物成分可包含例 如濕氣、電解質、酵素、揮發氣體、細菌、血液等。穿戴 者成分亦可包含皮膚 '生殖器、肛門、肛門括約肌等。物 件成分亦可包含腿部摺邊 '腰部摺邊或其他廢棄物障壁及 /或包含成分 '側片、翼、底座、吸收核心、吸納成分、 固定系統、縱向緣或端緣等。電位能可以機械能、電能、 化學或熱能。本發明所用之“動能”表示做工或進行上述反 應功能之能力(如壓縮裝置膨脹、扭轉裝置旋轉、改變相 而移動之凝膠、皮膚或排泄物之包覆或處理、酵素抑制、 p Η調整等)。 約束二維結構產生捕捉廢棄物涉及例如在物件成分上或 最終在廢棄物上進行之反應功能。例如捕捉廢棄物 '擦拭 穿戴者皮膚或以護膚組合物、抗微生物劑、抗眞菌劑或酵 素抑制劑處理皮膚爲在廢棄物及/或穿戴者上進行之反應 功能《調整物件幾何學(於一 '二或三維)或物理性質(如 彎折模數、幾何等)爲可在物件上進行之反應功能實例。 對看護者及/或穿戴者發出事件發生或約略發生之訊號於 本發明中亦視爲反應功能。訊號可爲視覺、聽覺、觸覺、 電學、化學或生物學。可拋棄物件之促動器例如可輸送脱 臭劑、酵素抑制劑、抗微生物劑、抗眞菌劑、護膚組合物 或Ρ Η控制劑;捕捉、擦拭、覆蓋、虜獲 '固定、密封、 -34- 本紙張尺度適用中國國家標準(CNS)A4規格(210 χ 297公釐) ί------------裳--------訂---------線 (請先閱讀背面V/注意^項#』寫本頁) 587 A7 B7 五、發明說明(32 ) 系送或儲存人體廢棄物;或約制設計成進行一或多個該等 功能或視廢棄物、穿戴者、物件或其成分而進行之任何其 他反應性功能之結構或元件釋出或產生。 本發明促動器可釋出位能以因廢棄物、穿戴者、物件或 其成分而進行或活化反應功能。位能釋出可將機械、電、 化學或熱位能轉化成機械能、電能或化學動能以進行反應 功能。促動器可受輸入之閥値制約以釋出位能而進行反鹿 功能或可對上述之輸入連續反應,例如,壓縮之發泡體具 有儲存之壓縮機械位能且當其釋出時可提供機械動能。扭 轉發泡體具有當釋出時可提供機械動能,亦即旋轉之儲存 扭轉機械位能。此外,儲存化學、電或熱能可用以釋出 電 '機械、化學或熱動能。可拋棄物件之促動器例如可包 含或^個下列:儲存乳液、抗微生物劑、抗眞菌劑、排 泄物改質劑、酵素抑制劑、pH緩衝劑、染料、加壓氣 體、壓縮發泡體、扭轉發泡體,泵、密閉系統液體輸送元 件、電感應凝膠、pH感應凝膠、研感應凝膠等。位能可 以任何足以維持或保存之方式儲存直至需要時釋出。唯持 及/或儲存此能量之適宜裝置包含電池及/或電容器、電扭 轉之壓縮伸張材料或結構,呈可進行物理或化學功能之材 料態(如吸收劑、軟化劑、pH緩衝劑、酵素抑制劑、排迪 物改質劑、壓縮氣體等)。 或者’本發明促動器可包括具有進行或活化因廢棄物、 =者、物件或其任何成分之反應功能之能力之許多儲存 材科。-具體例中’例如,促動器可釋出或輸送儲存材料 -35- &amp;張尺料財關家辟x;公g . ! I (請先Μ讀背面·之注意Ϋ-項戸、寫本I) 訂. -線- A? 4^Ί 587 _______Β7 五、發明說明(33 ) 以進行反應功能。此具體例中,促動器可受輸人之闕値制 約以在既定時間斷續輸送儲存材料或可連續釋出或輸送材 料。例如促動器可包含儲存乳液、護膚组合物、抗微生物 劑、抗眞菌劑、排泄物改質劑、酵素抑制劑、pH緩衝 劑染料等。某些較佳具體例中,材料可藉促動器輸送如 膨脹彈性材料、釋出之高壓氣體等。 圖2及2A説明包括在壓差裝置91中以至少部分眞空下密 封之壓縮彈性材料94如發泡體之促動器9〇。本文所用之 壓差裝置爲可維持彈性材料在壓縮狀態(如可藉對壓縮彈 f生材料9 4 &amp;供限制壓力而儲存能量)之任何裝置或結構。 壓縮狀態”定義爲材料維持在比未限制材料及在零壓力下 更小之體積之狀況。有關彈性材料,壓縮狀態通常可藉施 加壓力至材料表面或藉本技藝悉知之任何其他方式達成。 壓差裝置例如包含眞空密封袋或張力材料如彈性或無彈性 帶或索 ' 繩、薄膜' 不織布、棉織品或發泡體,其可ρ艮制 彈性忖料。較好藉壓差裝置91維持彈性材料壓縮可經由制 約機制至少部分降低(亦即壓縮彈性材料以可至少部分膨 脹)。制約機制爲可對輸入反應以在壓差裝置9丨中進行壓 力平衡並使壓縮彈性材料94至少部分膨脹之任何元件或裝 置,如感測器、促動器或其組合,壓縮材料釋放後,如當 偵測標的生物分析物時,壓縮彈性材料可膨脹且輸送儲存 材料。有些具體例中,對促動器有利者爲包括空隙空間 9 6 0 彈丨生材料可包括任何彈性材料,包含(但不限於.)Eva發 -36- 本纸張巾_爾5NS)A4g⑵〇x 297公发) ----------------------訂·-------- (請先閱讀背面·之注意t項#丄'寫本頁) 經濟部智慧財產局員工消費合作社印*1衣 42 158 A7 B7 五、發明說明(34 泡體如賓州愛迪司通之Foarnex公司以稱爲SIF/210PP1或 Aquazone 80A發泡體所提供者或由Μ A亥尼斯之Sentinel產 物公司稱爲MC1900 EVA 2磅/立方呎或HIPE發泡體所提供 者’如述於DesMarais等人於1993年1 1月9曰發證之 USP5,260,345標題爲“用於水性人體流體之吸收發泡體材 料及含此材料之吸收物件,Dyer等人於1995年2月7曰發 證之USP5,387,207標題爲“水性人體流體用之薄濕吸收發 泡體材料及其製法”;及DesMarais於1997年7月22日發證 之USP 5,625,222標題爲“由具有極高水對油比例之高内相 乳液製得之水性流體用之吸收發泡體材料,’所述者(各專利 均併於本文供參考)。 本發明有些具體例中,壓差裝置91可包括可溶袋。可溶 袋可在一或多種輸入如水、尿液、排;世物酵素、p Η値等 存在下溶解且可具有可設計設定溶解該袋所須之輸入間値 之物理及/或化學特性(如厚度)。可溶袋可例如包括可溶 於水之塑膠膜如由IL南荷藍Chris-Craft工業產物工業以5. Description of the Invention (29) Any sensor 60 of the present invention may be placed and / or operatively connected to any part of a disposable object 'which may be exposed to an input designed by the sensor to detect it. For the purpose of the present invention, “movably connected” means that the communication device enables the sensor 60 to detect the input 2 to the object 2 Some sensors 60 can be separated and operatively connected to the following: sensing = two copies , Another sensor 60, an actuator, a controller, or some other part or component of the object 20. "Operably connected" may include, for example, an electrical connection for communication via conductive coils or components, via transmission signals such as radio frequency, infrared or other transmission frequencies. Alternatively, the sensor 60 may be operatively connected via a mechanical connection such as a gas or hydraulic connection. In the specific example of disposable items printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs (see diaper 2 of Fig. 1), the sensor 60 can be located in front of the object 20, the waist region 36 ', the rear waist region 38, or the cross region 3 7 It can be integrated with the base 22, the upper layer 24, the bottom layer 26, the absorbent core 28, the side panel 30 ', the leg hem 32, the waist feature 34, the fixing system 40', the longitudinal edge 50, or the end edge 52, etc. In, connected to, or including those parts. In a preferred specific example in which the target biological analyte is used in combination with human waste, the 'sensor 60' can be placed in the area where the object 20 intersects to maximize the contact between the human waste and the sensor. Among other preferred specific examples in which the sensor is suitable for detecting or measuring the target biological agent on the skin of the wearer, the sensor 60 can be placed on the object to know the upper layer, the hem, the waist characteristics, the excrement receiving bag, the interval Or any other material that will come into contact with the wearer's skin during use. In a specific example, the sensor may also use lotions or other skin care compositions in the object. The sensor 6 0 can be integrated into the object 2 0 or can be worn by the caregiver or wearer. -32- This paper size is applicable to the 0 standard (CNS) A4 (210 X 297 mm) I 58 A7 B7 Ministry of Economic Affairs Printed by Intellectual Property Bureau's Consumer Cooperatives V. Invention Description (30). The sensor can also become at least partially detached from the object and can be attached to the wearer's skin during wear of the object. The sensor can be fixed (permanently or detachably) (such as via a mechanical fixing system such as Velcr0TM or a water-soluble adhesive) to the monolithic structure 'contains tape, fiber or synthetic cloth, fluff, film, cotton, Foam ¥. Furthermore, the sensor 60 may be completely contained in an object such as the object 20 or may have a receiving portion located in the object and may be in contact with a required input and other portions such as a conductive portion located inside or outside the object. The sensor ⑹ can be external to the object 20 but still connected to some parts of the object 2 0, so that the sensor 60 can detect inputs outside the object and provide signals to the controller and / or actuator. In some specific examples, the sensor can be separated from the object, such as applied to some parts of the wearer through an adhesive or other means known in the art, and / or can have one or more components separated from the object. In some specific examples, a wiping device or element can be installed to allow the wearer or caregiver to fully clean human waste, and the signal can be evaluated or read visually (especially for specific examples of sensors equipped with this signal). ) ^ The wiping element may include cloth (fiber or synthetic), non-woven high fluffy material, film, foam, rigid or semi-rigid roller-like elements and similarly placed in the object and suitable for making the element clean for sensing Monitor. The wiping element can be fixed to the object of the proximity sensor 60 at least by any known means known in the art as above. The wiping device may optionally include water or any known cleaning aid to facilitate cleaning of the wearer or sensor display. In a preferred embodiment, the object 20 may also include an actuator. The “actuator” mentioned in this manual means a device including a “potential” and a device that converts the potential to perform or activate a “reaction function”. The potential of the actuator may include storage or The scale is applicable to China National Standard (CNS) A4 specification (210 X 297 mm) —ί ----------- installation · I ί! Order --------- line (please first Read the "Note on the back" · Xiang Yi <write this page) Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs 4 21 bay A7 ______B7 V. Description of the invention (31) Potential energy or storage. Therefore, the actuator can be borrowed. Potential is converted into kinetic energy or a reaction function is performed or activated by transporting a stored substance. "Reaction function" is defined for the purposes of this document ^ as a function of human waste, the wearer or its components, or a signal to the wearer or caregiver Human waste components can include, for example, moisture, electrolytes, enzymes, volatile gases, bacteria, blood, etc. Wearer components can also include skin 'genitals, anus, anal sphincter, etc. Object components can also include leg hem's waist Hemming or other waste barriers and / or Containing ingredients' side panels, wings, bases, absorbing cores, absorbing components, fixing systems, longitudinal edges or end edges, etc. Potential energy can be mechanical energy, electrical energy, chemical or thermal energy. The "kinetic energy" used in the present invention means work or carry out the above The ability to respond (such as compression device expansion, twisting device rotation, phase-changing gel, skin or excrement coating or treatment, enzyme inhibition, p Η adjustment, etc.) Constraining the two-dimensional structure to generate waste capture involves For example, reaction functions on object components or ultimately on waste. For example, capture waste 'wipe the wearer's skin or treat skin with skin care compositions, antimicrobials, antibacterial agents, or enzyme inhibitors. The reaction function performed on the wearer "Adjusting the object geometry (in one, two or three dimensions) or physical properties (such as bending modulus, geometry, etc.) is an example of the reaction function that can be performed on the object. For caregivers and / Or the signal from the wearer that an event occurred or approximately occurred is also considered as a reaction function in the present invention. The signal may be visual, auditory, tactile, electrical Science, chemistry or biology. Actuators that can dispose of objects such as deodorants, enzyme inhibitors, antimicrobials, antimicrobials, skin care compositions, or P control agents; capture, wipe, cover, capture ' Fixed, sealed, -34- This paper size is applicable to China National Standard (CNS) A4 specification (210 x 297 mm). -------- line (please read the V / note ^ item # on the back page first to write this page) 587 A7 B7 V. Description of the invention (32) To send or store human waste; The release or generation of structures or elements of one or more of these functions or any other reactive function depending on the waste, wearer, object, or its components. The actuator of the present invention is releasable to perform or activate a reaction function due to waste, a wearer, an object, or a component thereof. Potential energy release converts mechanical, electrical, chemical or thermal potential energy into mechanical, electrical or chemical kinetic energy for reaction functions. The actuator can be controlled by the input valve to release the potential energy and perform the anti-deer function or can continuously react to the above input. For example, the compressed foam has the stored compression mechanical potential energy and can be released when it is released. Provides mechanical kinetic energy. The twisted transfer bubble has mechanical torsional mechanical energy that can provide mechanical kinetic energy when it is released, that is, rotation. In addition, storage of chemical, electrical or thermal energy can be used to release electrical 'mechanical, chemical or thermal kinetic energy. Disposable actuators may include, for example, or the following: storage emulsions, antimicrobials, antimicrobials, excrement modifiers, enzyme inhibitors, pH buffers, dyes, pressurized gases, compressed foam Body, torsion foam, pump, closed system liquid transport element, electrical induction gel, pH induction gel, research induction gel, etc. Bit energy can be stored in any manner sufficient to maintain or preserve it until it is released. Suitable devices that only hold and / or store this energy include batteries and / or capacitors, electrically twisted stretched materials or structures in a material state that can perform physical or chemical functions (such as absorbents, softeners, pH buffers, enzymes Inhibitors, excipient modifiers, compressed gases, etc.). Alternatively, the actuator of the present invention may include many storage materials having the ability to perform or activate a reaction function due to waste, a subject, an object, or any of its components. -In the specific example, 'for example, the actuator can release or transport the storage material-35- &amp; Zhang ruler material wealth Guanjiapi x; public g.! I (Please read the note on the back first-item 戸, Written I) Order. -Line- A? 4 ^ Ί 587 _______ Β7 V. Description of the invention (33) for reaction function. In this specific example, the actuator may be constrained by the loser to intermittently transport the storage material at a given time or may continuously release or transport the material. For example, the actuator may include a storage emulsion, a skin care composition, an antimicrobial agent, an anti-bacteria agent, an excrement modifier, an enzyme inhibitor, a pH buffer dye, and the like. In some preferred embodiments, the material can be delivered by an actuator such as an expanded elastic material, a high-pressure gas released, and the like. 2 and 2A illustrate an actuator 90 including a compressed elastic material 94, such as a foam, which is hermetically sealed in a differential pressure device 91 at least in part. As used herein, a differential pressure device is any device or structure that can maintain the elastic material in a compressed state (for example, it can store energy by compressing the compressed material 9 4 &amp; for limiting the pressure). "Compression state" is defined as the condition in which the material is maintained in a smaller volume than the unrestricted material and under zero pressure. For elastic materials, the compression state can usually be achieved by applying pressure to the surface of the material or by any other means known to the art. Pressure The differential device includes, for example, an airtight sealed bag or a tension material such as an elastic or non-elastic band or rope, a rope, a film, a non-woven fabric, a cotton fabric, or a foam, which can be made of elastic material. Compression can be at least partially reduced by a restriction mechanism (that is, the compression elastic material can be at least partially expanded). The restriction mechanism is any that can respond to the input to pressure balance in the pressure differential device 9 and at least partially expand the compression elastic material 94. A component or device, such as a sensor, an actuator, or a combination thereof, after the compressed material is released, such as when the target biological analyte is detected, the compressed elastic material can expand and transport the stored material. In some specific cases, the actuator It is advantageous to include the void space 9 6 0. The elastic material may include any elastic material, including (but not limited to) Eva hair-36- Paper towel_ Seoul 5NS) A4g⑵〇x 297 public hair) ---------------------- Order · -------- (Please read first Note on the back of the item # 丄 'write this page) Printed by the Consumers ’Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs * 1 clothing 42 158 A7 B7 V. Description of the invention (34 Foamex company of Edison Stone, Penn. Supplied by SIF / 210PP1 or Aquazone 80A foam or referred to as MC1900 EVA 2 lb / cu.ft. Or supplied by HIPE foam by Sentinel Products, Inc., as described in DesMarais et al. 1993 1 USP 5,260,345 issued on January 9th is entitled "Absorbable foam material for aqueous human fluids and absorbent articles containing this material. USP 5,387,207 issued on February 7, 1995 is entitled" "Thin Moisture Absorbing Foam Material for Aqueous Human Fluids and Its Preparation Method"; and USP 5,625,222, issued by DesMarais on July 22, 1997, entitled "Prepared from a High Internal Phase Emulsion with Very High Water to Oil Ratio" The absorbent foam material for water-based fluids, as described above (each patent is incorporated herein by reference). In some specific examples of the present invention, the differential pressure device 91 may include a soluble bag. The soluble bag can be dissolved in the presence of one or more inputs such as water, urine, excretion; enzymes, p Η 値, etc., and can have physical and / or chemical properties that can be designed to set the input gap required to dissolve the bag ( (Such as thickness). Soluble bags can include, for example, water-soluble plastic films such as those produced by IL South Holland Chris-Craft Industrial Products Industries.

MONOSOL M7031、M7030、M8630、M8534或E6030膜所提 供之PVC膜或由MN聖保羅H.B· Fuller公司以HL 1636或HL 1669-X所提供者。此膜厚度例如亦可經改質以提供所需活 化作用。所用之膜例如亦可具有约〇·〇005至約0 〇〇丨5忖之 厚度。例如後約0.001吋之HL 1636薄膜可以每平方叫·約 0.049克之澄氣含量活化。 促動器或可包括電感應凝膠。電感應凝勝爲至少部份以 水膨潤時在施加電流或電場時可改變體積及/或幾何學之 -37- 本紙張尺度適用中國國家標準(CNS)A4規格(210x 297公釐) 請 先 閱 讀 背 之-注 意 事· 項 I裝 頁 訂 線 經濟部智慧財產局員工消費合作社印製 經濟部智慧財產局員工消費合作社印製 丨 be 7 A7 -----------B7___ 五、發明說明(35 ) 聚合凝膠網路。例如,某些部分離子化聚丙烯醯胺凝膠當 浸潰於丙酮及水中時在弱電場(如〇 5伏特/公分)下經歷約 50%疋觸變收縮。或者,電感應凝膠在水及界面活性劑中 可經歷電诱發f摺或當進行震動電場時可經歷震動波動 作。相信在部分凝膠中如凝膠元件之一側可藉集中正電荷 界面活性劑分子在電場中負電荷凝膠聚合物上而誘發局部 敏縮°當一側長度降低時(如繩狀凝膠可捲曲),改變強度 及/或電場極性可誘發凝膠移動。電感應凝膠可包括可變 之幾何學如長方形、圓形、網格等圖形以在其改變容積及 /或幾何學時’提供釋出材料之閥’使人體廢棄物通過, 避免人體廢棄物流出’包封人體廢棄物等。電感應凝膠片 例如可f摺而當偵測到外肛門括約肌預測排泄或排尿時之 電活性時可提供空隙空間。MONOSOL M7031, M7030, M8630, M8534 or E6030 film is supplied by PVC film or HL 1636 or HL 1669-X by MN Sao Paulo H.B. Fuller Company. This film thickness can also be modified, for example, to provide the desired activation. The film used may also have a thickness of, for example, about 0.0005 to about 0.005 忖. For example, the HL 1636 film of about 0.001 inches can be activated with a clear gas content of about 0.049 grams per square. The actuator may include an electrical induction gel. Electrical induction is at least partly based on water swelling that can change volume and / or geometry when an electric current or electric field is applied. -37- This paper size applies to Chinese National Standard (CNS) A4 (210x 297 mm). Read the back-Notes · Item I Binding Line Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs be 7 A7 ----------- B7___ Five Description of the invention (35) Polymer gel network. For example, some partially ionized polypropylene ammonium gels experience about 50% thixotropic thixotropic shrinkage when immersed in acetone and water under a weak electric field (eg, 0.5 volts / cm). Alternatively, the electro-inductive gel may undergo electrical induction in water and surfactants or may undergo vibrational fluctuations when subjected to a vibrating electric field. It is believed that in some gels, such as one side of the gel element, localized contraction can be induced by concentrating positively charged surfactant molecules on the negatively charged gel polymer in the electric field. When the length of one side is reduced (such as a rope-like gel) Can be curled), changes in intensity and / or electric field polarity can induce gel movement. The electro-inductive gel can include variable geometries such as rectangles, circles, grids, etc. to change the volume and / or geometry to 'provide a valve for the release of materials' to allow human waste to pass through to avoid the flow of human waste Out 'encapsulated human waste, etc. The electro-sensitive gel sheet can be folded, for example, and can provide a void space when the electrical activity of the external anal sphincter is detected to predict excretion or urination.

圖5 A及5 B中’例如電感應凝膠片494以電路顯示,其中 排泄物瘦氣可連接觸點485並使電流流至使片彎摺或變直 線之電感應凝膠。或者,在長方形格栅圖形595中所形成 之電感應凝膠594(如圖6A ' 6B及6 C所示)當偵測到急迫排 尿時可電誘發膨潤或皺縮而形成使及/或避免尿液流至物 件2 0其他部分之値。例如圖6 a顯示包含長方形格柵圖形 之電感應凝膠。圖6 B及6 C又分別顯示於皺縮格柵及於膨 潤狀態之微觀圖形。例.舉之材料爲弱交聯之pAMPs凝膠 (聚(丙缔酿胺-2 -甲基丙烷)磺酸)。此類凝膠可進行各種 功能如施用或輸送化學排泄處理劑。其他例舉之電感測凝 膠述於於1990年3月31日發證之USP 5,100,933及WO -38- 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) 丨! 1!!裝.1! — — — 訂·! 線 (請先閱讀背面,之注意事項鼻寫本頁) A7 4 2 1 58 7 五、發明說明(36 ) 9202005中,兩者均併於本文供參考。或者,分別在特定 pH或鹽濃度時改變容積及/或幾何學之pH感應凝膠或鹽濃 度感應凝膠可做爲本發明促動器。 促動器可置於及/或動作連接至可拋棄物件之任何部 分,而可使促動器因人體廢棄物、穿戴者或其成分而進行 反應功能。物件2 0中,例如促動器可置於物件2 〇之前腰 部區域36、後腰邵區域38或交叉區域37,且可與底座 2 2 '上層2 4、底層2 6、吸收核心2 8、側片3 0、腿部摺邊 3 2、腰部特徵3 4、固定系統4 〇 '縱向緣5 〇或端緣5 2等成 分整體整合、鄰置於其上或結合於其上。促動器亦可完全 含於物件如物件2 0中,可部分置於物件中及部分置於物件 2 0外,或可完全在物件2 〇外。促動器或部分促動器可動 作地連接至一或多個感測器6 〇 ' 一或多個控制器8 〇、並 他部分之促動器或物件2 0其他部分上。再者,促動器7 〇 可與物件20整合或可藉看護者或穿戴者裝設。 經濟部智慧財產局員工消費合作社印製 物件2 0亦可包含控制器。“控制器,,就本發明目的定義爲 自感測器接收輸入且若採取一或多個作用時予以測定之裝 置。控制器可接收來自感測器6 〇之訊號並指示促動器進行 因人體廢棄物、穿戴者、物件或其成分之反應功能。或 者’促動器7 0可接收直接來自感測器6 〇之訊號並進行因 人體廢棄物、穿戴者、物件或其成分之反應功能。控制器 可包含經歷化學或物理改變之材料,其可爲進行感測器等 資訊之化學、機械或電裝置。感測器6〇可包含包括多層 Langmuir-Blodgett膜,其至少部分可作爲控制器之功能, -39- 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公芨) 經濟部智慧財產局員工消費合作钍印製 421587 A7 ____B7____ 五、發明說明(37 ) 其中一或多層包含生物辨識元件。與水接觸後,Langmuir-Blodgett膜已知可自發地重組,導致比原來膜及具有更少 層之其他區域更多層之區域。此重組可使生物辨識元件暴 露至存在有水如人體廢棄物(其可含有標的生物分析物)之 環境中。此可降低生物感測器之假陽性及/或延遲儲存壽 命。或者’自電化學感測器接收訊號如電位能之電控制器 可接收並追蹤多數電訊號且可重複制約促動器。控制器可 與感測器成分整合、與促動器成分整合或爲系統之個別成 分。 控制器可置於及/或動作地連接至可抛棄物件之任何部 分’其可使控制器接收來自感測器6 〇之訊號並對促動器提 供訊號。物件2 0中,例如控制器可置於物件2 〇之前腰部 區域36、後腰部區域38或交又區域37,且可與底座22、 或其上層2 4成分、底層2 6、吸收核心2 8、側片3 0、腿部 摺邊32 '腰部特徵34、固定系統40、縱向緣5〇或端緣52 等成分整體整合、鄰置於其上或結合於其上。控制器可與 物件20整合或可藉看護者或穿戴者裝設。控制器可完全含 於物件如物件2 0中,可部分置於物件中及部分置於物件 2 〇外’或可完全在物件2 〇外。控制器或部分控制器可動 作地連接至一或多個感測器6 0、一或多個促動器9 〇 '其 他邵分之控制器或物件2 0其他部分上。例如,控制器可接 收來自感測器6 0之訊號並藉無線電頻率(rf)傳送對促動器 7 〇提供訊號。 雖然不同結構元件可進行感測器6 〇、促動器及控制器之 -40- 尺;關家標準(CNS)A4規格⑵〇 χ 297公爱 -~~ I--—1'— —------------I — J11. — — — I ____ (請先閱讀背面之注意’項卢ί寫本頁) 58? A7 B7 經濟部智慧財產局員工消費合作社印製 五、發明說明(38 功旎’但本發明感測器6 〇、促動器及/或控制器功能不需 错不同結構元件進行。例如,感測器60及控制器功能可藉 相同結構元件而進行。 “反應感測器”本發明目❸中定義爲包含感測器60及當感 測器60偵測適宜制約輸入時對人體廢棄物、穿戴者 '物: 或其成分作用之促動器之系統。感測既定輸入參數時,促 動器進行儲存能量之釋出或輸送料材料以進行反應功 flt,例如,當包含傳導器之原活化感測器6 0偵測逼迫事件 時’傳導器對促動器提供訊號進行儲存能量釋出。在逼追 事件I則藉僧測輸入訊號,物件中之反應系統可制約以準 備該事件或對穿载者或看護發出該逼迫事件之訊號。此可 架構(物件爲其中廢棄物處理或處理技術最初先隱藏但在 需要移動之時或恰在之前及/或其中物件可對看護或穿戴 者提供事先準備該事件之責任(如在偵刺致病微生物或殘 留排泄物疗染之事件時對穿戴者投與預防治療)。無闕於 特定輸入’該等具體例中之感測器6。可制約促動器以對物 件、穿载者或物件進行作用以準備事件發生或對看護提供 逼迫事件將發生之訊號。若感測器㈣包括感測系統,則— 促動器可界不同感測器及,或訊號而制约或不同促動器可 藉不同感測器及/或訊號致約。或者,—感測器及/或訊號 -41 - 本纸ίίΪ尺度適用令@國家標準(CNS)AJ現格(21〇 χ视公^ ) I. 1—!裝--------訂---------線---- (請先閱讀背面t注意^項再人寫本頁) 4 ^ 1 5 8 五、發明說明(39) 可制約數個促動器。 本發明之反應系統可以“連續,,或“不連續”方式反應。本 發明所用之“連續反應系統”表示其中輸出與輸入量有定量 關係之系統,亦即連續增加輸入量需要連續増加輸出量, 或反應系統輸出包括儲存材料被動釋出。例如,置於物件 吸收核心之超吸收$合物提供其中輸出與輸入量冑定量關 係之連續反應’巾即增加量之液體廢棄物與超吸收聚合物 接觸時,聚合物含有之液體量增加直至聚合物容量耗盡。 化學4量化學反應爲具有連續反應系統以增加輸出之另— 實例。例如在反應A +反應卜c中,過量B轉化成c之量爲 化學計量且因此“連績,,表示系统中提供之A量。 然而,“不連續反應系統”表示具有實質上與闕値以外之 輸入量無關之輸出功能之反應系統。例 田付兮一或多 個既定閥値時,反應系統可釋出所有或欲設定部分之儲存 能量,亦即活化地傳送所有或欲設定部分之儲存能量以進 行特定反應功能。本發明理想具體例中,輸出函^⑷包 含圖3A所示之“步進”函數。此具體例中,輸出隨輸入増 加量之變化率(d(輸出)/d(輸入)),亦即輸出函數““之第 -衍生値Γ⑴之斜率’當輸入量高於或低於間値時較好實 質上爲零。然而,閥値時,d(輸出)/d(輸入)改變率較好 -42- 本义度i_s用十3因家標準(CNSW-l規烙(210 X 297lTi7 i丨丨丨|丨|!! — ·裝i I (請先W讀背面·之注意^-項# ;.寫本頁) 訂- ^;^部智«?財產局員工消費合作社印製 421 58 A7 B7In Figs. 5A and 5B, for example, the electro-sensitive gel sheet 494 is shown by a circuit, in which fecal thin gas can be connected to the contact 485 and a current flows to the electro-sensitive gel which bends or straightens the sheet. Alternatively, the electric induction gel 594 formed in the rectangular grid pattern 595 (as shown in FIGS. 6A '6B and 6 C) can be electrically induced to swell or shrink to form and / or avoid when urgent urination is detected. Urine flows to the rest of the object 20. For example, Figure 6a shows an induction gel containing a rectangular grid pattern. Figures 6B and 6C show the micrographs in the shrunk grid and in the swollen state, respectively. For example, the material is weakly cross-linked pAMPs gel (poly (2-aminopropyl-2-methylpropane) sulfonic acid). Such gels can perform various functions such as applying or delivering a chemical excretion treating agent. Other examples of inductive gel are described in USP 5,100,933 and WO-38 issued on March 31, 1990. This paper size applies to China National Standard (CNS) A4 (210 X 297 mm) 丨! 1 !! 装 .1! — — — Order ·! (Please read the back of the page first, the notes should be written on this page) A7 4 2 1 58 7 V. Description of the invention (36) 9202005, both are incorporated herein for reference. Alternatively, a pH sensing gel or a salt concentration sensing gel that changes volume and / or geometry at a specific pH or salt concentration, respectively, can be used as an actuator of the present invention. The actuator can be placed and / or operatively connected to any part of the disposable object, allowing the actuator to perform a reaction function due to human waste, the wearer or its components. In the object 20, for example, the actuator can be placed in the front waist region 36, the rear waist region 38 or the cross region 37 before the object 20, and can be connected with the base 2 2 'upper layer 2 4, bottom layer 6, absorbent core 2 8, Side panels 30, leg hem 3 2, waist characteristics 3 4, fixing system 4 0 'longitudinal edge 50 or end edge 5 2 and other components are integrated, placed next to or combined on it. The actuator may also be completely contained in an object such as object 20, may be partially placed in and partially outside object 20, or may be completely outside object 20. The actuator or part of the actuator is operatively connected to one or more sensors 6 0 ', one or more controllers 8 0, and other parts of the actuator or object 20 other parts. Furthermore, the actuator 70 may be integrated with the article 20 or may be installed by a caregiver or wearer. Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs. Object 20 may also include a controller. "The controller, for the purposes of the present invention, is defined as a device that receives input from a sensor and measures it if one or more actions are taken. The controller can receive a signal from the sensor 60 and instruct the actuator to perform a cause. Human waste, wearer, object or its component's reaction function. Or 'actuator 70 can receive the signal directly from the sensor 60 and perform the reaction function due to human waste, wearer, object or its component. The controller may include materials undergoing chemical or physical changes, which may be chemical, mechanical, or electrical devices that perform information such as sensors. The sensor 60 may include a multilayer Langmuir-Blodgett film, which at least partially serves as a control Function of the device, -39- This paper size is in accordance with Chinese National Standard (CNS) A4 (210 X 297 gong). It is printed by the Intellectual Property Bureau of the Ministry of Economic Affairs for employee consumption cooperation. 421587 A7 ____B7____ One of the invention or (37) The multi-layer contains biometric elements. The Langmuir-Blodgett membrane is known to reorganize spontaneously after contact with water, resulting in more layers than the original membrane and other areas with fewer layers This reorganization may expose the biometric element to an environment where water such as human waste (which may contain the target biological analyte) is present. This may reduce false positives and / or delay the shelf life of the biosensor. Or ' An electrical controller that receives signals such as potential energy from an electrochemical sensor can receive and track most electrical signals and can repeatedly restrict the actuator. The controller can be integrated with the sensor components, integrated with the actuator components, or integrated into the system. Individual components. The controller can be placed and / or operatively connected to any part of the disposable object 'which enables the controller to receive a signal from the sensor 60 and provide a signal to the actuator. In the object 20, for example The controller can be placed in the front waist region 36, the rear waist region 38, or the cross-over region 37 of the object 20, and can be combined with the base 22, or its upper layer 24, the bottom layer 2, the absorbent core 2, the side panel 30, Leg hem 32 'waist feature 34, fixing system 40, longitudinal edge 50 or end edge 52 are integrally integrated, adjacent to or combined with it. The controller can be integrated with the object 20 or can be borrowed by the caregiver Or wearer equipment. The device may be completely contained in an object such as the object 20, may be partly placed in the object and partly outside the object 20, or may be completely outside the object 20. The controller or part of the controller may be operatively connected to one or more Sensor 60, one or more actuators 90, other controllers or other parts of the object 20. For example, the controller may receive signals from the sensor 60 and use radio frequency ( rf) Transmits the signal to the actuator 70. Although different structural elements can be used for the sensor 60, the actuator and the controller are -40-feet; Guan Family Standard (CNS) A4 specification ⑵〇χ 297 public love -~~ I --— 1'— —------------ I — J11. — — — I ____ (Please read the note on the back first to write this page) 58? A7 B7 Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs. 5. Description of the invention (38 functions), but the sensor 6 of the present invention, the actuator and / or the controller function need not be performed with different structural elements. For example, the functions of the sensor 60 and the controller may be performed by the same structural elements. "Response sensor" is defined in the objective of the present invention as a system including a sensor 60 and an actuator that acts on human waste, the wearer's object, or its components when the sensor 60 detects a suitable restriction input. . When a given input parameter is sensed, the actuator releases stored energy or conveys material to perform the reaction work flt. For example, when the original activation sensor 60 containing the transducer detects a forcing event, The actuator provides a signal to release the stored energy. In the chase event I, the monk measures the input signal, and the reaction system in the object can be restricted to prepare for the event or send a signal of the persecution event to the wearer or the caretaker. This can be structured (the object is where waste disposal or treatment technology was initially hidden but was just before or just when it needed to be moved and / or where the object could provide the caregiver or wearer with the responsibility to prepare the event in advance (such as Preventive treatment is given to the wearer in the event of infection with diseased microorganisms or residual fecal matter). No specific input 'sensor 6 in these specific examples. Actuators can be restricted to target objects, wearers or The object acts to prepare for an event or to provide a signal to the caregiver that an impending event will occur. If the sensor does not include a sensing system, then-the actuator can be bound to different sensors and, or the signal is restricted or different actuator Can make an agreement by different sensors and / or signals. Or, —Sensors and / or signals -41-This paper is applicable to the standard @National Standards (CNS) AJ 现 格 (21〇χ 视 公 ^) I 1—! Outfit -------- Order --------- Line ---- (Please read the note on the back t before writing this page) 4 ^ 1 5 8 5. (39) Several actuators can be restricted. The reaction system of the present invention can react in a "continuous," or "discontinuous" manner. The "continuous reaction system" used in the present invention refers to a system in which the output has a quantitative relationship with the input, that is, continuously increasing the input requires continuous increase in the output, or the output of the reaction system includes the passive release of storage materials. For example, it is placed on an object to absorb The core superabsorbent compound provides a continuous reaction in which the output is in a quantitative relationship with the input amount. That is, when an increased amount of liquid waste comes into contact with the superabsorbent polymer, the amount of liquid contained in the polymer increases until the polymer capacity is exhausted. A chemical 4 chemical reaction is another example with a continuous reaction system to increase output. For example, in reaction A + reaction c, the amount of excess B converted to c is stoichiometric and therefore "continuous," meaning that it is provided in the system The amount of A. However, "discontinuous reaction system" means a reaction system with an output function that is substantially independent of input quantities other than 阙 値. For example, when one or more predetermined valves 値 are used, the reaction system can release all or The stored energy of the set part, that is, the stored energy of all or the set part to be activated is transmitted to perform a specific reaction function. In the ideal specific example, the output function ^ ⑷ contains the “step” function shown in FIG. 3A. In this specific example, the change rate of the output with the input amount (d (output) / d (input)), that is, the output The slope of the function "" -derivative 値 Γ⑴ 'is preferably substantially zero when the input amount is higher or lower than the interval 然而. However, at the valve ,, the d (output) / d (input) change rate is better- 42- The original meaning of i_s is based on the standard of 10 domestic standards (CNSW-l standard (210 X 297lTi7 i 丨 丨 丨 | 丨 | !! |) — Install i I (please read the back first. Note ^ -item #;. (Write this page) Order-^; ^ 部 智 «? Printed by the Property Bureau Staff Consumption Cooperative 421 58 A7 B7

經 濟 部 智 .¾ 財 產 局 員 工 消 費 合 社 印 U 五、發明說明(40 ) 達無限。因此,理想不連續反應中,當ε〜〇時函數《ΙΕ 極限不等於ε — 〇時函數f(x+ ε )極限,亦即υ 'lim- t(x- ε ) ^ nmf(x+^ ει ε -&gt;〇 :而’本發明趙認在物理世界中在間値之理想不連續步 進未必改變且在許多例中甚至不可能。較佳具體例中,在 或約在輸入閥値左右輸出函數僅需具有隨輸入極少變化之 可見步進變化。因此,本發明期待具有輸出函數之本發= 不連續反應系統在傳送區域中係以充分不連續之方^ 應,使得在傳送區域中輸出函數具有至少最小相對:二反 險峻性。雖然不欲受限於所述特定方法或模型化不連;: 統,但在測定是否既定輸出功能係以本發明目的所定 不連續方式進行之較佳方法中,在曲折點之輸出曲: 斜率與傳送區域中第-及最終點間之直線相對_率相當。 例如’圖4A顯示例舉之輸出函數f⑴圖形與例舉輸 之第- Γ⑻、第二f”⑻及第三f ”(χ)衍生値之排列圖形 出函數f(X)描述在輸出或反應(R⑴)時之輸入效果。就本發 明目的而言,傳送區域定義爲輸出函數叫之第二衍: f”⑻之相對最大R(Il)及十間叫)間之區域。相對最 ^ 及相對中間叩2)爲第三衍生値f,,(x)等於零時之點 ^ 點4定義爲轉折區域中第二衍生ΜΓ(χ)等於零時之點,亦 即Printed by the Ministry of Economic Affairs. ¾ Consumer and Consumer Affairs Bureau of the Property Agency. U. V. Invention Description (40) is unlimited. Therefore, in an ideal discontinuous reaction, when ε ~ 〇, the function ΙΕ limit is not equal to ε — 〇 when the function f (x + ε) limit, that is, υ 'lim- t (x- ε) ^ nmf (x + ^ ει ε -&gt; 〇: 'The ideal discontinuous step of the present invention in the physical world is not necessarily changed and is not even possible in many cases. In the preferred embodiment, it is output at or about the input valve. The function need only have a visible step change with little change in the input. Therefore, the present invention expects the origin of the output function = the discontinuous response system responds in the transmission area with a sufficiently discontinuous response ^ so that the output in the transmission area The function has at least a minimum relative: two anti-severity. Although not intended to be limited by the specific method or model, it is better to determine whether a given output function is performed in a discontinuous manner for the purposes of the present invention. In the method, the output curve of the tortuous point: the slope is equivalent to the relative _ rate of the straight line between the-and the final point in the transmission area. For example, 'Fig. 4A shows an example of the output function f⑴ graph and the example of the input-Γ⑻, the Two f "⑻ and third f "(Χ) derivation of the permutation pattern of the output function f (X) describes the input effect in the output or response (R⑴). For the purpose of the present invention, the transmission area is defined as the second derivative of the output function: f" ⑻ The area between the relative maximum R (Il) and ten). The relative maximum ^ and the relative middle 叩 2) is the third derivative 値 f, where (x) is equal to zero ^ Point 4 is defined as the second in the turning area Derive the point at which MΓ (χ) is equal to zero, that is,

d2R 0. dl2 I I=I〇 本紙張尺度適用㈣而⑵㈣7㈤ i 裝--------訂---------線. ftt先閱讀背面^/注音?Ϋ-項#4寫本頁) 421 58 A7 B7 五、發明說明(41 ) dR j (ART) k 經濟部智慧財產局員工消費合作社印製 〇 dI .1 1=1。 ( ΔΙτ ) 此程式中,轉折點之則!爲該點輸出函數之第一衍生 値:ΔΙΤ爲傳送區域之第一 ^及最後^點間之輸入對反應系 k亦即I:rI丨,及ARt爲傳送區域之第一及最後點 間之輸*函數反應之改變,亦即叩2)部1)。係數k爲描述 轉斤11 0之輸出函數斜率與傳送區域中第一及最終點間道 .泉斜率相較之相對險峻性之比例常數。爲了使反應系統具 有不連續輸出功能,比例常數k需至少約2〇,較好至少约 3.〇,更好至少约5.〇’甚至更好至少约]〇〇,以至少约1〇&lt; 最佳。 某&quot;'具姐例中,不連續反應系統之傳送區域中險峻性相 對红度5F可由具有—系列整數n(等時間常數之第—級延遲 (权制系轭傳送函數所模製。就本發明目的,反應系統之 傳送函數定義爲輸出(反應變數)對輸入(猜疑變數)之 Laplace 又換比例。例如參見 R〇bert Η 及D〇n Green, 第六版,第 22 章(McGraWHill,Inc 1984)。如圖4B所示,輸出函數之險峻性相對程度約略爲 式KG(s)-K/(Ts+l)n ’其中KG(s)爲傳送函數,κ爲比例元 素’ τ爲系統時間函數,及η爲第一級延遲之整數。此模 土中η値增加’則傳送區域中輸出函數險峻性增加,及 44 -------------裝--------訂---------線 {請先閱讀背面_之注意Ϋ-項#-毛寫本頁) 經濟部智慧財產局員工消費合作社印製 421587 五、發明說明(42 ) 模型開始接近不連續反應系統。本發明之某些不連續反應 系統較好可由上式所模型化,當η大於或等於約2 5,以n 大於或等於約5 0更佳,且η大於或等於約100最佳。 如圖3 Α所示,本發明之反應系統可包含單一閥値,該時 反應系統可釋出所有儲存能量以進行特定之反應功能,或 可包含多數閥値’該時系統可釋出預設計部分之儲存能量 以在各閥値進行一或多個特定反應功能。具有單一閥値之 具體例中’例如’當閥値符合時反應系統可釋出所有儲存 此量。此單—閥値具體例中,不連續反應系統包含具有兩 種狀態如開或關之系統。當吸收物件中存在輸入如人體廢 棄物疋閾値量時,反應系統可因廢棄物、穿戴者' 物件或 其成分而進行單一反應功能,如包住使用者皮膚所排出之 廢棄物。因此,不連續反應系統可進行再輸入閥値存在下 由一狀態改變成另一狀態之單次“似開關,,功能。 或者,如圖3 B所示,反應系統可具有多個閥値,該時當 符合各闕値時,系統可釋出既定“量’,之能量或輸送既定量 之材科以進行特定反應功能。此具體例中,當符合各閥値 時,可進行部分整個反應功能及/或符合不同閥値時進行 不同獨1反應功能。例如,反應系統可追縱排泄物酵素且 當2合各閥値時可輸送等量或不等量之酵素抑制劑,或可 在弟一閥値時膨脹物件儲存成分或輸送pH緩衝劑並進行 ^ —反應功能如在第二閥値時輸送大量酵素抑制劑。各傳d2R 0. dl2 I I = I〇 This paper size is suitable for ㈣7㈤ i installed -------- order --------- line. ftt first read the back ^ / Zhuyin? Ϋ-item # 4 write this page) 421 58 A7 B7 V. Description of the invention (41) dR j (ART) k Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economy 〇 dI .1 1 = 1. (ΔΙτ) The turning point in this program! Is the first derivative of the output function at this point: ΔΙΤ is the input pair response between the first ^ and last ^ points of the transmission area, i.e., I: rI 丨, and ARt is the first and last point between the transmission areas. Input * function changes, that is, 亦 2) part 1). The coefficient k is a proportionality constant describing the relative steepness of the slope of the output function of the rotary jack 110 and the slope of the spring between the first and final points in the transmission area. In order for the reaction system to have a discontinuous output function, the proportionality constant k needs to be at least about 20, preferably at least about 3.0, more preferably at least about 5.0 'or even more preferably at least about 100%, and at least about 10% Best. In a certain example, in the transmission area of the discontinuous reaction system, the severity relative redness 5F can be molded by a series of integers n (the first-order delay of the equal time constant (the weight system is the yoke transmission function.) For the purpose of the present invention, the transfer function of the reaction system is defined as the ratio of the output (reaction variable) to the input (suspect variable). For example, see Robert Η and Don Green, Sixth Edition, Chapter 22 (McGraWHill, Inc 1984). As shown in Figure 4B, the relative severity of the output function is approximately KG (s) -K / (Ts + l) n 'where KG (s) is the transfer function and κ is the proportional element' τ is The system time function and η are integers of the first-order delay. Increasing η 中 in this model soil increases the danger of the output function in the transmission area, and 44 ------------- 装- ------ Order --------- line {Please read the note on the back _-item # -written page) Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs 421587 5. Description of the invention (42) The model begins to approach a discontinuous reaction system. Some discontinuous reaction systems of the present invention are preferably modeled by the above formula, when η is greater than It is equal to about 25, preferably n is greater than or equal to about 50, and η is greater than or equal to about 100. As shown in FIG. 3A, the reaction system of the present invention may include a single valve 値, and the reaction system may be released at this time. All stored energy can be used to perform a specific reaction function, or it can include most valves. At this time, the system can release the pre-designed part of the stored energy to perform one or more specific reaction functions at each valve. Specific to a single valve In the example 'for example', the reaction system can release all the stored quantities when the valve is matched. In this single-valve example, the discontinuous reaction system includes a system with two states such as open or closed. When present in the absorbent article When inputting a threshold amount such as human waste, the reaction system can perform a single reaction function due to waste, the wearer's object or its components, such as covering the waste discharged from the user's skin. Therefore, the discontinuous reaction system can perform Then re-enter a single "switch-like, function" that changes from one state to another in the presence of valve 或者. Alternatively, as shown in FIG. 3B, the reaction system may have multiple valves 符合, which should meet each 该System, the system can release a given "quantity" of energy, or deliver a given amount of material to perform a specific reaction function. In this specific example, when each valve is met, part of the entire reaction function can be performed and / or different valves are met Different unique reaction functions can be performed at the same time. For example, the reaction system can track excrement enzymes and can deliver equal or unequal amounts of enzyme inhibitors when 2 valves are closed, or can swell objects when the valve is closed. Store ingredients or deliver pH buffers and carry out reaction functions such as delivering a large number of enzyme inhibitors during the second valve.

送區域中’在上逑單_閥値具體例中反應系统反應實質上 與傳送區域相同D 45· 本紙張尺度福家標準(CNS)x^r2iQ x 297公爱) ii I -----In! M ml--—訂---------線 ί請先閲讀背面^注意^-項#丨.寫本頁} 42 1 58 A? B7 經濟部智慧財產局員工消費合作社印製 五、發明說明(43 ) 此外,反應系統可追縱數個輪入如一或多個致病細菌及 /或一或多種排泄物酵素且當符合不同輸入之閥値時進行 —或多個反應功能,或當符合兩個或多個不同輸入閥値時 可僅進行一個反應功能。因此,控制器可追蹤多個不同輸 入且當符合不同輸入閥値時進行不同反應功能。或者,控 制器可進行邏輯OR-閘極型功能使得當符合多數輸入之一 或多個閥値時可進行反應功能。控制器亦可進行邏輯 AND-閘極型功能使得當符合兩個或多個不同輸入之各閥 値時可進行反應功能。 反應系統亦可包括“密閉迴路,’或“開放迴路”系統。亦稱 爲“反饋控制迴路”系统之“密閉迴路”系統包含不同感測器 6 0及促動器成分且因輸入而進行反應功能。有些具體例 中’反應功能之至少一個制約機因輸入而進行時,系統亦 可使用輸出條件之元件或參數之偵測或測量。輸出條件可 爲促動器已有機會在輸入條件下進行反應功能之後之輸入 條件狀態。當輸出狀態達閥値時可進行反應功能或當符合 輸出狀態及一或多個其他狀態時僅進行反應功能。因輸入 之作用可包含因所感測之元件而作用,例如感測微生物並 因該微生物而作用或可包含因感測元件之組成爲整體成分 而作用’如感測排泄物細菌並因穿戴者皮膚上之排泄物或 殘留排泄物而作用。如上所述,回饋控制迴路包含至少兩 個不同成分:感測器6 〇及促動器。感測器6 〇偵測事件或 事件伴隨之參數。促動器接收訊號並進行因感測器6 〇所偵 測之輸入狀態而進行反應功能。回饋控制迴路又可包含控 -46 l·------------裝 i — (請先閱讀背面y注意ί·項再4寫本頁) 4-0... •線. Z ίχ 格 4 η ,0 一 公 /1 y 42 彳 58 7 A7 B7 經濟部智慧財產局員工消費合作社印制农 五、發明說明(44〉 制器。此例中,感測器60提供控制器訊號且控制器指導促 動器進行輸入條件之反應功能。控制器可爲反應系統之個 別成分或控制器功能可藉感測器6〇及/或促動器進行。 回饋控制迴路可爲‘‘非調節”或“調節,,者。“非調節,,回饋 控制迴路反應系统中,反應系統作爲單次開關作用,其中 當符合輸出條件閥値時促動器對輸入進行反應功能。例 如,感測器6 0可偵測特定特定致病微生物之存在或測量濃 度’及促動器可對看護發出潛在初期傳染之訊號。此例 中,促動器因感測器6 0所偵測之輸入而作用。然而,“調 節’’回饋控制迴路包含感測器6 〇、促動器及控制器。調節 回饋控制迴路中,輸出條件係持續或重複追跛且控制器指 導促動器進行輸入之反應功能以保持輸出條件在所須設定 點或在所須範圍内或提供連續測量各値或標的生物分析物 濃度。 然而’“開放迴路”系統爲反應於輸入而未使用回饋進行 反應功能之系統,亦即輸出對進入系統之感測輸入無作 用。開放迴路系統可包含具有可同時進行感測器6 0及促動 器功能之單一裝置之反應系統,或可具有不同感測器6 0及 促動器成分,其中促動器因輸入以外之物質而作用。例如 置於可抛棄吸收物件之吸收核心中之超吸收聚合物提供開 放迴路反應,因爲聚合物僅包含可進行感測器6 0及促動器 功能之單一裝置。或者,開放迴路系統可包含偵測人體廢 棄霧或人體廢棄物成分之感測器6 0及促動器以連續或不連 續方式在感測器6 0所偵測之輸入以外之物質上進行反應功 -47- 本纸張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) --------- ---· I I &lt;請先間讀背面t注意W-項乒人寫本頁) 訂· -線· 4 2 1 5 8 7 · A7In the delivery area, the reaction system reaction in the specific example of the “Single Valve” is substantially the same as the delivery area. D 45 · This paper standard (Fujian Standard (CNS) x ^ r2iQ x 297 public love) ii I ----- In ! M ml --- order --------- line ί Please read the back ^ Note ^ -item # 丨 .Write this page} 42 1 58 A? B7 Printed by the Consumers ’Cooperative of Intellectual Property Bureau, Ministry of Economic Affairs V. Description of the Invention (43) In addition, the reaction system can track several turns into one or more pathogenic bacteria and / or one or more fecal enzymes and perform when the valve of different inputs is met-or multiple reaction functions , Or only one reaction function can be performed when two or more different input valves 符合 are met. Therefore, the controller can track multiple different inputs and perform different reaction functions when different input valves 値 are met. Alternatively, the controller can perform a logical OR-gate type function to allow a reactive function when one or more of the valves 値 are met. The controller can also perform a logic AND-gate type function so that when two or more valves with different inputs are matched, a reaction function can be performed. The response system can also include a "closed loop," or "open loop" system. A "closed loop" system, also known as a "feedback control loop" system, contains different sensors 60 and actuator components and reacts on input. Function. In some specific examples, the system can also use the components or parameters of the output conditions to detect or measure when at least one of the control functions of the response function is performed by the input. The output conditions may be that the actuator already has the opportunity under the input conditions. The state of the input condition after the reaction function is performed. The reaction function can be performed when the output state reaches the valve or only the reaction function when the output state and one or more other states are met. Because the role of the input can include due to the sensed component, Actions, such as sensing and acting on microorganisms, or may include acting as a whole component of the sensing element, such as sensing fecal bacteria and acting on excreta or residual excreta on the wearer's skin. As above The feedback control loop includes at least two different components: a sensor 60 and an actuator. The sensor 60 detects an event or Parameters accompanying the device. The actuator receives the signal and performs a response function due to the input state detected by the sensor 60. The feedback control loop can also include control -46 l · ---------- -装 i — (Please read the y note on the back first and then write this page) 4-0 ... • Thread. Z ίχ Grid 4 η, 0 One male / 1 y 42 彳 58 7 A7 B7 Ministry of Economic Affairs The Intellectual Property Bureau employee consumer cooperative prints the farmer ’s fifth, invention description (44) controller. In this example, the sensor 60 provides a controller signal and the controller instructs the actuator to respond to input conditions. The controller can be a response Individual components or controller functions of the system can be performed by sensors 60 and / or actuators. The feedback control loop can be `` non-regulated '' or "regulated," or "non-regulated," the feedback control loop reaction system In response, the reaction system acts as a single switch, where the actuator responds to the input when the output conditions are met. For example, the sensor 60 can detect the presence or measurement of the concentration of a specific pathogenic microorganism. The actuator can signal a potential initial infection to the caregiver. In this case, the actuation The sensor works because of the input detected by the sensor 60. However, the "regulation" feedback control loop includes the sensor 60, the actuator and the controller. In the adjustment feedback control loop, the output conditions are continuous or repeated Tracking and the controller directs the actuator to perform input response functions to keep the output conditions at the required set points or within the required range or to provide continuous measurement of the concentration of each analyte or target biological analyte. However, the "" open loop "system is A system that responds to inputs without using a feedback function, that is, outputs that have no effect on the sensing inputs that enter the system. An open-loop system may include a single device response with simultaneous sensor 60 and actuator functions The system may have different sensors 60 and actuator components, where the actuators act on substances other than inputs. For example, a superabsorbent polymer placed in the absorbent core of a disposable absorbent article provides an open loop response because the polymer contains only a single device that can perform the functions of the sensor 60 and the actuator. Alternatively, the open-loop system may include a sensor 60 that detects human waste fog or human waste components and an actuator that reacts in a continuous or discontinuous manner on a substance other than the input detected by the sensor 60 Gong-47- This paper size is applicable to China National Standard (CNS) A4 (210 X 297 mm) --------- --- · II &lt; Please read the back first t Note W-item Ping man writes this page) Order · -line · 4 2 1 5 8 7 · A7

經濟部智慧財產局員工消費合作社印製 五、發明說明(45 ) 其他反應系统述於1998年6月2 9日申請之美國專利申請 號09/106,424標題爲“具不連續反應系統之可拋棄物 件’’(P&amp;G案號7197): 1998年6月29日申請之美國專利申請 號09/107,563標題爲“具有包含回鎖迴路之反應系统之可抛 棄物件’’(P&amp;G案號7198);及1998年6月29曰申請之美國專 利申凊號09/106,225標題爲“具有包含機械促動器之反應系 统之可拋棄物件”(P&amp;G案號7199);各均併於本文供參 考= 本發明尿片20實例可包含包括圖i所示之感測器6〇及圖 2所示之促動器之反應系統。此具體例中,感測器6 〇可包 括與適於偵測排泄物中E. coli之生物辨識元件動作連接之 傳導器。藉生物辨識元件特異地偵測E. c〇li閥値,傳導器 可以電流對促動器發出訊號。圖1所示之物件可包含促動 器其包含眞空密封在水可溶膜9 1中之壓縮彈性材料94, 如圖2所示(如PVA膜)。自感測器接收適宜訊號,促動器 可關閉開關,例如可釋出小量之儲存水以接觸並溶解水可 溶膜9 1。此導致壓縮發泡體中儲存之機械能釋出。彈性材 料9 4膨脹並形成間隔物以提供初期排泄物之孔隙容積。或 者’開耳封閉物又可釋出抗微生物劑以控制E. c〇1丨及/或釋 出可見染料以對穿载者或看護發出E· c〇ii存在之訊號。另 一具體例中,反應系統可包含使看護或穿载者留意逼迫事 件之促動器,如痢疾感染或皮膚刺激(如念珠菌病)。 其他具體例中,本發明包括可偵測或使使用者留意特定 -48 - 本纸張尺度適用中國國家標準(CNS)A4規格(21〇 X 297公釐) LI I----------裝--------^ · I I ------- (請先間讀背面之注音?Ϋ項声Λ寫本頁) 421 58Printed by the Employees ’Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs. 5. Description of the Invention (45) Other reaction systems are described in US Patent Application No. 09 / 106,424, filed on June 29, 1998, entitled“ Disposable Objects with Discontinuous Reaction System ” '' (P &amp; G Case No. 7197): U.S. Patent Application No. 09 / 107,563, filed June 29, 1998, entitled "Disposable Objects with a Reaction System Containing a Lockback Loop" (P &amp; G Case No. 7198 ); And U.S. Patent Application Serial No. 09 / 106,225, filed June 29, 1998, entitled "Disposable Articles with a Reaction System Containing a Mechanical Actuator" (P &amp; G Case No. 7199); each of which is incorporated herein by reference. For reference = An example of the diaper 20 of the present invention may include a reaction system including a sensor 60 shown in FIG. I and an actuator shown in FIG. 2. In this specific example, the sensor 60 may include a transmitter connected to a biometric element suitable for detecting E. coli in fecal matter. By using the biometric element to specifically detect the E. coli valve, the transmitter can signal the actuator with an electric current. The object shown in FIG. 1 may include an actuator including a compressive elastic material 94 hollowly sealed in a water-soluble film 91, as shown in FIG. 2 (such as a PVA film). The self-sensor receives a suitable signal, and the actuator can turn off the switch. For example, a small amount of stored water can be released to contact and dissolve the water-soluble film 9 1. This results in the release of mechanical energy stored in the compressed foam. The elastic material 94 expands and forms a spacer to provide the pore volume of the initial excreta. Or, the 'open-ear closure may release an antimicrobial agent to control E.coi and / or release a visible dye to signal the presence of E.coi to the wearer or caregiver. In another specific example, the response system may include actuators that alert caregivers or wearers to persecution events, such as dysentery infections or skin irritation (such as candidiasis). In other specific examples, the present invention includes the ability to detect or draw attention to specific -48-This paper size is applicable to the Chinese National Standard (CNS) A4 specification (21 × X 297 mm) LI I ------- --- Equipment -------- ^ · II ------- (Please read the Zhuyin on the back? Ϋ Xiangsheng ΛWrite this page) 421 58

五、發明說明(4g ) 人體覆蓋物如手覆蓋物。手覆蓋物可部 覆:或身體任何其他部位。較好,感測器通常 :於或靠近至少部分外表面。手覆蓋物實例包含(但不限 :):套、手套 '四指相連之手套及手巾。較好,此人體 覆路物爲可拋棄者。此覆蓋物可用於醫藥護理及評價、動 物學及獸醫學看護及評估、與植物或活產品、食物製備及 處理(欲由人體或其他活動物所消耗之商業或家用兩者)有 關之農業事務。 另-具體例中’本發明可包括欲由人體或其他活動物所 消耗之食品使用纟可偵W或使使用者留意特定生物狀況之 食品處理'儲存或製備物件。較好,此物件爲可拋棄。較 好感測器通常置於或靠近預期與食品接觸或鄰置之表面部 分。物件可用於處理各種處理或製備階段之食品原料或處 理以製備之食品。此物件可包含食品製備物、覆蓋物及片 材’可爲剛性或撓性;食品儲存材料如剛性容器、剛性容 器襯禮或表面、較好由撓性材料製得之食品儲存包裝材; 及食品服務物件如盤子、小盤子、大盤子、手巾、食品包 裝材及片材’其可爲剛性或撓性,以代用品方式作用。 測試方法 反應因子測試: 有關後文所述之反應因子測試.,可測量反應暴露至特定 物質或組成時定量感測器之反應。 此測試之特定物質或组合物宜包含·· 濃度爲每1克生理食鹽水約1克排泄物測試材料之水溶液排 -49 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) I.---------------裝.......訂---------線 &lt;請先閱讀背面t注意Ϋ-項爭4寫本頁) 經 濟 部 智 慧 財 產 局 消 費 合 作 社 印 *1 _____1 42 158 7 A7 __ B7 ' ______________ 五、發明說明(47 ) 泄物測試材料; 濃度爲每1克測試尿液溶液約1克排泄物測試材料之測試琢 液溶液排泄物測試材料; 濃度爲每1克生理食鹽水約180克糞臭素之生理食鹽溶液 之糞臭素溶液;及 生理食鹽溶液》 所有測量均在體溫(3rc)進行《測試包含依下列順序之 下列步驟: 1 )紀錄感測器暴露至生理食鹽溶液24小時後定量反 應。背景反應爲最大紀綠反應。 2 )使感測器暴露至特定物質或組合物中。 3 3感測器仍暴露至特定物質或組合物中24小時時紀 錄感測器定量反應。物質反應爲最大紀綠反應。 以背景反應使物質反應公稱化而獲得反應因子。此例 中,反應因子小於i,反應因子之相互値纪綠爲反應因 子。 經濟部智慧財產局員工消費合作社印製 雖然已説明並描述本發明之特定非限制性具體立即實例 及/或個別特徵,但熟悉本技藝者將了解在不達離本發明 之精神及範圍内可作各種其他改變及修飾。例如雖然本發 明王要以可抛棄物件説明並描述,但本發明不限於此具體 例。本發明例如可在施用可抛棄尿片或置換可抛棄尿片之 則以全拉開尿片 '尿片插入物、衛生棉' 棉球等使用於 直接應用至穿戴者之物件(如穿载者括約肌或括約肌區域) 中。再者,須了解此種具體例及特 、ω 1 j汉狎徵之·所有組合均可能且 -50-本紙張尺度適用中断紐靴NS)A4規格⑽χ视公^ 587 A7 _B7 五、發明說明(48 ) 可產生本發明之較佳執行。因此意欲於附綠之申請專利範 園中含括所有在本發明範圍内之改變及修飾。 -------------裝--------訂---------線 (請先閱讀背面t注意事項兵足寫本頁) 經濟部智慧財產局員工消費合作社印製 -51 - 本纸張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐)5. Description of the invention (4g) Human body coverings such as hand coverings. Hand coverings can cover: or any other part of the body. Preferably, the sensor is usually on or near at least part of the outer surface. Examples of hand coverings include (but are not limited to :): sleeves, gloves, gloves with four fingers and hand towels. Preferably, this human body cover is disposable. This cover can be used for medical care and evaluation, zoology and veterinary care and evaluation, agricultural affairs related to plants or live products, food preparation and processing (both commercial and domestic for consumption by humans or other live animals) . In another specific example, the invention may include the use of food to be consumed by the human body or other live animals, food processing to store or prepare objects that can detect or make the user aware of specific biological conditions. Better, this object is disposable. Better sensors are usually placed on or near parts of the surface that are expected to come into contact with or be adjacent to food. Objects can be used to process food ingredients in various processing or preparation stages or processed to prepare food. This article may include food preparations, coverings and sheets that may be rigid or flexible; food storage materials such as rigid containers, rigid container linings or surfaces, food storage packaging materials preferably made of flexible materials; and Food service items such as plates, small plates, large plates, hand towels, food packaging materials, and sheets can be rigid or flexible, acting as a substitute. Test method Response factor test: The response factor test described below can measure the response of a quantitative sensor when a reaction is exposed to a specific substance or composition. The specific substance or composition for this test should contain an aqueous solution drain at a concentration of about 1 gram of fecal test material per 1 gram of normal saline -49 This paper size applies to China National Standard (CNS) A4 (210 X 297 mm) ) I .--------------- install ....... Order --------- line &lt; please read the back t note Ϋ-Item 4 (Write this page) Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs * 1 _____1 42 158 7 A7 __ B7 '______________ V. Description of the invention (47) Leach test material; The concentration is about 1 gram of excreta test per 1 gram of test urine solution Testing of materials: Liquid solution excrement test materials; skatole solution with a physiological salt solution at a concentration of approximately 180 grams of skatole per 1 gram of physiological saline; and physiological salt solution. All measurements were performed at body temperature (3rc). The following steps are performed in the following order: 1) Record the quantitative response of the sensor after 24 hours of exposure to the physiological salt solution. The background response is the maximum age green response. 2) Exposing the sensor to a specific substance or composition. The sensor's quantitative response is recorded when the sensor is still exposed to a specific substance or composition for 24 hours. The material reaction is the maximum green reaction. The reaction is normalized by the background reaction to obtain the reaction factor. In this example, the response factor is less than i, and the mutual green of the response factors is the response factor. Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs, although specific non-limiting specific instant examples and / or individual features of the present invention have been illustrated and described, those skilled in the art will understand that the present invention may be used without departing from the spirit and scope of the present invention. Make various other changes and modifications. For example, although the present invention is described and described in terms of disposable objects, the present invention is not limited to this specific example. For example, the present invention can be used to dispose a disposable diaper or replace a disposable diaper with a fully opened diaper 'diaper insert, tampon' cotton ball, etc., which can be used for objects directly applied to the wearer (such as a wearer) (Sphincter or sphincter area). In addition, it is necessary to understand such specific examples and special, ω 1 j Han Zhengzheng · All combinations are possible and -50-this paper size is applicable to interrupt button boots NS) A4 specifications 视 χ See the public ^ 587 A7 _B7 V. Description of the invention (48) A better implementation of the present invention can be produced. Therefore, it is intended to include all changes and modifications within the scope of the present invention in the patent application park with green attached. ------------- Equipment -------- Order --------- line (please read the note on the back first to write this page) Ministry of Economy Wisdom Printed by the Employees' Cooperative of the Property Bureau -51-This paper size is applicable to China National Standard (CNS) A4 (210 X 297 mm)

Claims (1)

V 修正| 補充 421587 ^ AR 第8811〇98〇號專利申請案 g 中文申請專利範圍修正本(89年8月)S 、申請專利範圍 1. 一種適於穿载者之可拋棄物件,包括: 包含至少一個生物辨識元件之生物感測器,該生物 感測器適於偵測人體廢棄物中或穿载者皮膚上之標的 生物分析物。 2 ·根據申凊專利範圍第1項之可拋棄物件,其中該生物辨 識元件包括生物活性劑。 3. 根據申凊專利範圍第1項之可拋棄物件,其中生物威測 器#選自生物催化生物感測器及生物親和性生物感測 器之组群,其中該生物親和性感測器較好選自化學受 體為主之生物感測器及免疫感測器。 4. 根據申請專利範圍第1 ’ 2或3項之可抛棄物件,其中生 物辨識元件係選自下列:酵素或酵素序列、抗體、 DNA、器官器 '膜受體蛋白質、天然或合成細胞膜、 可見或非可見細菌、植物或動物細胞、至少部分之神 經束、至少部分至感應器官、波梅氏不動桿菌 (Acinetobacter baumannii)TOI36及桿菌屬丁0141。 5. 根據申請專利範圍第1 ’ 2或3項之可拋棄物件,其中生 物辨識元件係選自下列組群者:聚合物為主之材料、 水凝膠、薄片、不織布材料及織布材料。 6. 根據申请專利範圍第1,2或3項之可抛棄物件,其中該 生物感測器偵測選自下列組群之標的生物分析物:致 病細菌、結腸細菌、病毒、寄生蟲、細菌毒素、真 菌、酵素。 7. 根據申請專利範圍第6項之可拋棄物件,其中致疾細菌 本紙張尺度適用中國國家榇準(CNS ) A4規格(210X297公釐) (請先閲讀背面之注意事項再填寫本頁)V Amendment | Supplement 421587 ^ AR Patent No. 881110898 g Chinese Patent Application Amendment (August 89) S, Patent Application 1. A disposable object suitable for a wearer, including: A biosensor of at least one biometric element, the biosensor is adapted to detect a target biological analyte in human waste or on the skin of a wearer. 2. The disposable article according to item 1 of the scope of the patent application, wherein the biometric element comprises a bioactive agent. 3. The disposable object according to item 1 of the scope of patent application, wherein the biometric sensor # is selected from the group of biocatalytic biosensor and bioaffinity biosensor, and the bioaffinity sensor is better It is selected from chemical receptor-based biosensors and immunosensors. 4. Disposable objects according to item 1 '2 or 3 of the scope of patent application, wherein the biometric identification element is selected from the following: enzymes or enzyme sequences, antibodies, DNA, organ organ membrane receptor proteins, natural or synthetic cell membranes, visible Or non-visible bacteria, plant or animal cells, at least part of the nerve bundle, at least part of the sensory organs, Acinetobacter baumannii TOI36 and Bacillus Ding 0141. 5. The disposable items according to item 1 ′ 2 or 3 of the scope of the patent application, in which the biometric identification element is selected from the group consisting of a polymer-based material, a hydrogel, a sheet, a non-woven material and a woven material. 6. The disposable object according to claim 1, 2 or 3, wherein the biosensor detects a target biological analyte selected from the following groups: pathogenic bacteria, colon bacteria, viruses, parasites, bacteria Toxins, fungi, enzymes. 7. Disposable objects according to item 6 of the scope of patent application, including disease-causing bacteria. The paper size is applicable to China National Standard (CNS) A4 (210X297 mm) (Please read the precautions on the back before filling this page) 經濟部中央梯準局員工消費合作社印製 421587 A8 B8 C8 D8 修iL補.开 六、申請專利範圍 係選自下列組群:大腸埃希氏菌(Escherichia coii);傷 寒沙門氏菌(Salmonella typhi)、副傷寒沙門氏菌 (Salmonella prartyphi)、腸炎沙 Η 氏菌(Salmonella enteriditis)、鼠傷寒沙門氏菌(Salmonella typhimurium); 海德爾堡沙門氏菌(Salmonella heidelberg);索氏志賀氏菌(Shigella sonnei) '弗氏志贺 氏菌(Shigella flexneri)、鲍氏志賀氏菌(Shigella boydii) 及痢疾志賀氏菌(Shigella dysenteriae);霍亂藏菌 (Vibrio cholerae);結核分歧桿菌(Mycobacterium tuberculosis);小腸結腸炎耶耳森氏菌(Yersinia enterocolitica);嗜水氣單胞菌(Aeromonas hydrophila); 類志贺鄰單胞菌(Plesiomonas shigelloides);空腸纟著曲 桿菌(Campylobacter jejuni)、大腸桿菌(Campylobacter coli) ’脆弱擬桿菌(Bacteroides fragi丨is);及梭菌包含敗 毒梭菌(Clostridia septicum)、產氣莢膜梭菌(Clostridia perfringens)、肉毒梭菌(Clostridia botulinum)及難難梭 菌(Clostridia difficile)。 經濟部中央標準局員工消費合作社印製 {請先閲讀背面之注^^項再填寫本頁) 备.根據申請專利範圍第1,2或3項之可拋棄物件,其中在 狀況臨床可見病徵發病之前,該生物感測器偵測與穿 戴者全身性或皮膚健康狀況有關之標的生物分析物。 9. 根據申請專利範圍第丨,2或3項之可拋棄物件,其中該 生物感測器又包括傳導器,較好選士包含電化學、光 學、熱及聲音傳導器之組群。 10. 根據申請專利範圍第i,2或3項之可拋棄物件,其中物 本紙張尺度適用Α4ί^ ϊ -2- 421587Printed by 421587 A8 B8 C8 D8 for repair of iL supplements by the Consumer Cooperatives of the Central Government Bureau of the Ministry of Economic Affairs. The scope of patent applications is selected from the following groups: Escherichia coii; Salmonella typhi; Salmonella paratyphi (Salmonella prartyphi), Salmonella enteriditis, Salmonella typhimurium (Salmonella heidelberg); Shigella sonnei (Shigella sonnei) Shigella flexneri, Shigella boydii and Shigella dysenteriae; Vibrio cholerae; Mycobacterium tuberculosis; Yersinia enterocolitica Yersinia enterocolitica); Aeromonas hydrophila; Plesiomonas shigelloides; Campylobacter jejuni; Campylobacter coli; Bacteroides fragi丨 is); and Clostridium includes Clostridia septicum, Clostridium perfringens (Clostridia perfringens), Clostridium botulinum (Clostridia botulinum) and hard hard Clostridium (Clostridia difficile). Printed by the Consumer Cooperatives of the Central Standards Bureau of the Ministry of Economic Affairs {Please read the note ^^ on the back before filling this page). Previously, the biosensor detected target biological analytes related to the systemic or skin health of the wearer. 9. Disposable objects according to the scope of application patent No. 丨, 2 or 3, wherein the biosensor also includes a transducer, preferably a group comprising electrochemical, optical, thermal and acoustic transducers. 10. Disposable objects according to item i, 2 or 3 of the scope of patent application, where the paper size is applicable to Α4ί ^ ϊ -2- 587587 、申請專利範圍 ^---- 經濟部中央揉準局貞工消费合作社印製 件又包括生物感測器之清潔元件。 Π·根據申請專利範圍第1,2或3項之可拋棄物件,其中該 生物感測器係固定至擔體元件.及/或可與物件分離。 12.根據申請專利範圍第1,2或3項之可拋棄物件,其中该 生物感測器或擔體元件黏附至穿戴者皮'膚。 13_根據申請專利範圍第1 , 2或3項之可拋棄物件,又包括 當生物感測器偵測標的生物分析物時可進行反應功能 之促動器,該反應功能較好涔看護或穿载者發出訊 號。 14·根據申請專利範圍第13項之可拋棄物件,其中反應功 能係選自下列組群··孔隙容積、處理皮膚、產生發泡 系統及對看護發出訊號。 15. 根據申請專利範圍第1,2或3項之可拋棄物件,又包括 接收器及/或傳訊器。 16. 根據申請專利範圍第i,2或3項之可拋棄物件,其中當 暴露至排泄物時,生物感測器之反應因子至少為5。 Π_根據申請專利範圍第1,2或3項之可拋棄物件,其中當 暴露至濃度為每克生理食鹽溶液為18〇微克糞臭素之生 理食鹽水糞臭素溶液時,生物感測器之反應因子至少 為5。 18. —種適於穿戴者之可拋棄物件,包括: 適於在穿戴者人體排泄物中或在穿戴者皮膚上偵測 健康標記或營養標記之感測器。 19. 根據申請專利範圍第1 8項之可拋棄物件,其中健康標 ----------A------訂 (#先Μ讀背面之注意事項再嗔寫本育) -3- 421587 六、申請專利範圍 經濟部中央標準局員工消費合作社印装 記係選自下列組群:重金屬、放射活性物質、脂、酵 素、内源性分泌、蛋白質類物質、黏液及微生物。 20.根據申s青專利範圍第τ 9項之可抛棄物件_,其中重金屬 為鉛或汞。 .21.根據申請專利範圍第18項之可拋棄物件,其中營養標 記係選自下列組群:鈣、維他命、電解質、脂、脂肪 酸、皂' 胺基酸、酵素、膽汁酸及其鹽、類固醇及碳 水化合物。 22. 根據申請專利範圍第} 8,1 9,2 0或2 1項之可拋棄物 件’其中在肤況臨床可見病徵發病之前,該感測器偵 測與健康或營養狀況有關之標的健康及/或營養標記或 其中生物感測器偵測僅高於上述預定義之閥值之標的 健康及/或營養標記。 23. 根據申請專利範爾第1 8,1 9,2 0或2 1項友可拋棄物 件,其中感測器^又包括傳導器,較好選自包含電化 學、光學、熱及聲音傳導器。 24. 根據申請專利範圍第1 8,1 9,2 0或2 1項之可拋棄物 *件,其中感測器包括微晶片。 25. 根據申請專利範圍第1 8,1 9,2 0或2 1項之可拋棄物 件,又包括當感測器偵測健康標記或營養標記時可造 行反應功能之促動器。 26. 根據申請專利範圍第2 5項之可拋棄物件,其中促動器 將位能轉化以進行反應功能,該位能可為選自機械 能、電能及化學能之組群之一或多種。 4 本紙伕尺度適用中國國家標準(CNS )六4说格(210X297公著) 請 先 聞 之 注 2 訂 42158 咐修正補充 六、申請專利範圍 A8 B8 C8 D8 18,19,2〇 戒 21 項之 27, 根據申請專利範圍第1,2,3 可拋棄物件,另包括: 上層; 與上層連接之底層;及 置於上層與底層間之吸收核心。 28. 根據申請專利範圍第!,2,3,18,19,2〇或21項之 :拋棄吸收物件,其中可抛棄物件係選自下列组群: W生棉、尿片、訓練褲、插入物及成人尿失禁裝置。 29·根據申請專利範圍第丨6項之可拋棄吸收物件,其中生 物感測器當暴露至排泄物時之反應因子至少為丨〇。 30.根據申請專利範圍第2 9項之可拋棄吸收物件’其中生 物感測器當暴露至排泄物時之反應因子至少為2 〇 ° ---------於------訂 f請先閲請背面之注意Ϋ項再填窝本頁〕 經濟部中失標準扃貝工消費合作社印褽. 本紙佚尺度逋用中國國家標準(CNS ) A4規格(210X297公釐)Scope of patent application ^ ---- The printed parts of the Zhengong Consumer Cooperative of the Central Bureau of the Ministry of Economic Affairs include cleaning elements for biosensors. Π. Disposable objects according to item 1, 2 or 3 of the scope of patent application, wherein the biosensor is fixed to a carrier element and / or can be separated from the object. 12. The disposable object according to item 1, 2 or 3 of the scope of the patent application, wherein the biosensor or carrier element is adhered to the skin of the wearer. 13_ Disposable objects according to item 1, 2 or 3 of the scope of the patent application, and also include an actuator that can perform a reaction function when the biosensor detects the target biological analyte. The reaction function is better for care or wear The carrier sends a signal. 14. Disposable objects according to item 13 of the scope of patent application, wherein the reaction function is selected from the following groups: pore volume, skin treatment, foaming system generation, and signalling to the caregiver. 15. Disposable items according to item 1, 2 or 3 of the scope of patent application, including receivers and / or messengers. 16. Disposable objects according to item i, 2 or 3 of the scope of patent application, wherein the biosensor has a response factor of at least 5 when exposed to fecal matter. Π_Disposable items according to item 1, 2, or 3 of the scope of the patent application, where the biosensor responds when exposed to a physiological saline solution of skatole at a concentration of 180 micrograms of skatole per gram of physiological salt solution The factor is at least 5. 18. A disposable article suitable for a wearer, comprising: a sensor suitable for detecting health or nutrition marks in the body waste of the wearer or on the skin of the wearer. 19. Disposable items according to item 18 of the scope of patent application, in which the health mark ---------- A ------ order (# 先 MRead the notes on the back before copying the copy) -3- 421587 6. Scope of patent application The imprint of the Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs is selected from the following groups: heavy metals, radioactive substances, lipids, enzymes, endogenous secretions, proteinaceous substances, mucus and microorganisms. 20. Disposables according to item 9 of the patent application scope of __, where the heavy metal is lead or mercury. .21. The disposable article according to item 18 of the scope of the patent application, wherein the nutrition label is selected from the group consisting of calcium, vitamins, electrolytes, lipids, fatty acids, soap 'amino acids, enzymes, bile acids and their salts, and steroids. And carbohydrates. 22. According to the scope of the application for patents} 8, 19, 20 or 21 of the disposable items' wherein before the onset of clinically visible symptoms of skin conditions, the sensor detects the target health and nutritional conditions and And / or nutrition markers or health and / or nutrition markers in which the biosensor detects targets that are only above the predefined threshold. 23. According to the patent application Vall No. 18, 19, 20 or 21, disposable items can be disposed of, among which the sensor ^ also includes a conductor, preferably selected from the group consisting of electrochemical, optical, thermal and sound conductors. . 24. Disposable items * 18, 19, 20 or 21 according to the scope of patent application, wherein the sensor includes a microchip. 25. Disposable items according to claim 18, 19, 20, or 21, and an actuator that can perform a response function when a sensor detects a health mark or a nutrition mark. 26. The disposable object according to item 25 of the patent application scope, wherein the actuator converts potential energy to perform a reaction function, and the potential energy may be one or more selected from the group of mechanical energy, electrical energy, and chemical energy. 4 This paper scale applies to the Chinese National Standards (CNS) 6 (4) (210X297). Please note 2 of the first note. 42158 Order to amend and supplement. 6. The scope of patent application A8 B8 C8 D8 18, 19, 20 or 21. 27. Disposable objects according to the scope of patent applications 1, 2, and 3, including: the upper layer; the bottom layer connected to the upper layer; and the absorption core placed between the upper layer and the bottom layer. 28. According to the scope of patent application! , 2, 3, 18, 19, 20, or 21: Disposable absorbent articles, wherein the disposable articles are selected from the following groups: W raw cotton, diapers, training pants, inserts and adult urinary incontinence devices. 29. The disposable absorbent article according to item 6 of the patent application scope, wherein the biosensor has a response factor of at least when it is exposed to feces. 30. Disposable absorbent article according to item 29 of the scope of the patent application, wherein the biosensor has a response factor of at least 20 ° when exposed to excreta --------- 于 ----- -Please read the note on the back before ordering. Please fill in this page.] Standards in the Ministry of Economic Affairs (printed by the Shellfish Consumer Cooperative). The size of this paper is in accordance with China National Standard (CNS) A4 (210X297 mm).
TW088110980A 1998-06-29 1999-12-01 Disposable article having bodily waste component sensor TW421587B (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US9099398P 1998-06-29 1998-06-29
US09/107,561 US6149636A (en) 1998-06-29 1998-06-29 Disposable article having proactive sensors
US09/106,225 US6186991B1 (en) 1998-06-29 1998-06-29 Disposable article having a responsive system including a mechanical actuator
EP98120476A EP0997125A1 (en) 1998-10-29 1998-10-29 Measuring system and measuring sensor for detecting and measuring the presence of faeces in an absorbent article
US09/299,399 US6713660B1 (en) 1998-06-29 1999-04-26 Disposable article having a biosensor

Publications (1)

Publication Number Publication Date
TW421587B true TW421587B (en) 2001-02-11

Family

ID=27514466

Family Applications (1)

Application Number Title Priority Date Filing Date
TW088110980A TW421587B (en) 1998-06-29 1999-12-01 Disposable article having bodily waste component sensor

Country Status (1)

Country Link
TW (1) TW421587B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI617296B (en) * 2017-01-06 2018-03-11 Diaper structure with wireless transmission function

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI617296B (en) * 2017-01-06 2018-03-11 Diaper structure with wireless transmission function

Similar Documents

Publication Publication Date Title
US6399853B1 (en) Disposable article having fecal component sensor
US6479727B1 (en) Diagnostic panel
US6713660B1 (en) Disposable article having a biosensor
CA2336025C (en) Disposable article having bodily waste component sensor
TW482662B (en) Disposable article having bodily waste isolation device
US6436055B1 (en) Device having diarrhea diagnostic panel
US6342037B1 (en) Device having fecal component sensor
EP1091688B1 (en) Disposable article having proactive sensor
US6570053B2 (en) Disposable article having a proactive sensor
RU2614589C2 (en) System for detecting and monitoring body excretions using gas releasing substance intended for interactive inurement to toilet
JP2002542843A (en) Disposable and other supplies with detection devices
MXPA05001260A (en) Sensoring absorbing article.
TW436281B (en) Sensors for fecal material and hygienic article comprising such sensor
CA2334984A1 (en) Disposable article having bodily waste isolation device
TW408013B (en) Disposable article having proactive sensor
TW421587B (en) Disposable article having bodily waste component sensor
EP1092151B2 (en) Device having fecal component sensor
EP1091773B1 (en) Disposable article having bodily waste component sensor
TW476640B (en) Disposable article, article for detecting the presence of vaginal infections, and absorbent interlabial device
KR20010053327A (en) Disposable article having bodily waste component sensor
MXPA00012993A (en) Disposable article having bodily waste component sensor
MXPA01004283A (en) Hygienic articles containing sensors for fecal material
MXPA00012988A (en) Disposable article having proactive sensor
MXPA00012991A (en) Device having fecal component sensor

Legal Events

Date Code Title Description
GD4A Issue of patent certificate for granted invention patent
MM4A Annulment or lapse of patent due to non-payment of fees