經濟部中央標準局負工消費合作社印製 A7 ____B7 _五、發明説明（1 ) 〔發明所屬之技術領域〕 本發明爲關於抗菌紙，抗菌紙之製造方法，紙之抗菌 處理方法及紙用抗菌劑* 〔發明所欲解決之課題〕 現在，廣泛使用經抗菌處理之紙，而於紙之抗菌處理 中，期望有抄紙時之處理，對原紙之塗布或浸漬處理，使 用置入抗菌劑之印刷油墨的印刷之抗菌處理等各種處理方 法，及可適用於此些各種方法且具有髙抗菌活性之抗菌劑 的開發。 〔解決課題之手段〕 本發明爲解決上述課題，提供1 )經噚晻酸或該鹽處 理之抗菌紙，2 )以含有噚_酸或該鹽之液狀製劑將紙塗 布或浸漬之抗菌紙的製造方法，3 )於抄紙時在紙的分散 液中添加曙晻酸或該鹽之抗菌紙的製造方法，4 )以含有 腭喹酸或該鹽之液狀製劑將紙塗布或浸漬之紙的抗菌處理 方法，5 )以含有曙睡酸或該鹽之印刷油墨對紙進行印刷 之紙的抗菌處理方法，以及，6 )含有以噚喹酸或該鹽作 爲有效成分之紙用抗菌劑。 〔發明之實施型態〕 本發明中所使用之噚喹酸爲化學名5-乙基-5，8 一二氫—8 —氧代〔1，3〕二噚茂並〔4，5 — g〕喹 (讀先聞讀背面之注意事項再填寫本頁) Λ< 裝· 訂-- ___if 本紙張尺度適用中國國家橾隼（CNS } A4規格（210X297公釐） -4 - A7 B7 經濟部中央梯準局負工消费合作社印製 五、發明説明（2 ) 啉一 7 -羧酸之於 The Pesticide Manual第 1 0 版（ British Crop Protection Council發行），第 7 6 0 頁 中記載的抗菌性化合物，於本發明中具有抗菌活性之其任 意鹽，例如鈉鹽，鉀鹽等之鹸金屬鹽，銨鹽，有機銨鹽等 之一價鹽，鈣鹽，鎂鹽等之鹼土金屬鹽，鋅鹽，鋁鹽等之 二價以上之金靥鹽型式亦可使用。 本發明中所使用之紙並無特別限定，可以日本紙，西 洋紙，板紙，彼·囬职棋寺泊·租羾rp局封象，又，其紙製品 之筆記等之事務用品，便箋，封筒等之信件組（letter set)，報告用紙，情報用紙，無炭用紙，P P C用紙， 文件用紙，相簿用紙，包裝紙，紙箱用紙，醫院所使用之 症歷用紙和藥袋，紙尿布，紙被單，衛生棉，薄棉紙，農 業用育苗盒等亦可作爲本發明之對象》 對於紙之鸣晻酸或該鹽之處理方法並無特別限定，但 通常採用以苜侣吗瞪胲琪蕻盟乙彼肮製劑將紙蝥布现授澴 之處理方法。該液狀製劑之型態可列舉溶液，乳膠液，懸 浮液等》 此時，噚晻酸或該鹽於處理液（液狀製劑）中之濃度 一般爲0 . 0 0 1 0重量％ 使用鸣喹酸或該鹽之紙的抗菌處理方法，除了如上述 將紙塗布或浸渍之方法以外，可列舉以含有曙喹酸或該鹽 之印刷油墨對紙進行印刷之方法，於抄紙時在紙的分散液 中添加噚喹酸或該鹽之方法等。 以含有噚喹酸或該鹽之印刷油墨對紙進行印刷之情形 本紙張尺度適用中國國家標準（CNS > Α4規格（210Χ297公釐） 請 先 聞 讀 背 面 之 注 \i \ [I;裝 頁 訂 -5 - 經濟部中央標準局員工消費合作社印装 A7 B7 五、發明説明（3 ) 中，例如，預先於印刷油墨中令含有0. 01〜5重置％ 左右之噚喹酸或該鹽，並將該印刷油墨以噴墨印刷方式予 以噴霧印刷。 本發明之抗菌紙，於紙上通常保持可令喟喹酸或該鹽 出現抗菌效果之充分量，例如，約0. lmg/m2〜 8 0 0 〇mg/m2«B署喹酸或該鹽含量之下限，較佳爲 2mg/m2，更佳爲 2 Omg/m2，再佳爲 6 Omg/ m2左右，又，上限較佳爲4 0 0 Omg/m2,更佳爲 2 0 0 Omg/m2，再佳爲 2 0 Omg/m2 左右》 本發明之抗菌紙對於大腸桿菌等之埃希氏菌靥，金黃 色葡萄球菌等之葡萄球菌靥，銅綠假單胞菌，螢光假單胞 菌等之假單胞菌屬，普通變形菌等之變形菌靥，枯草桿菌 等之桿菌颶，產氣腸桿菌等之腸桿菌屬，肺炎克雷白桿菌 等之克雷白桿菌屬，沙雷菌靥等細菌具有抗菌效力。 〔實施例〕 其次，列舉實施例更詳細說明本發明，但本發明並非 僅被限定於以下之例。 尙，於以下之例中，％全部表示重量％。 首先，示出製造本發明抗菌紙中所使用之本發明之紙· 用抗菌劑的製劑例· 製劑例1 將噚喹酸鈉1 0克加至水9 0克中，並良好攪拌取得 本紙張尺度適用中國國家揉準（CNS ) A4规格（210X297公釐） -----^-----C tt-IΓ (請先閲讀背面之注$項再填寫本頁) -訂- 經濟部中央標準局身工消費合作社印裝 389809 at B7 五、發明説明（4 ) 1 0 %溶液。 製劑例2 於水2 0 0毫升中加入噚喹酸鈣1 〇克，以均質器於 20分鐘，約5000轉/分下攪拌，其次，加入 DEMOL N (花王股份有限公司製之分散劑）2克， 並再攪拌1分鐘取得分散液。 其次，示出抗菌紙之製造例。 製造例1 以噚喹酸鈉之0.1〜5. 0%水溶液，將文件原紙 之兩面各以2 0 g/m 2塗布，取得本發明之抗菌紙。 製造例2 於依製劑例2爲準所得之噚喹酸鈉之0. 5〜4. 0 分散液中配合以塗層色料，並在上質紙以氣刀塗料器於 1 6 g/m 2塗布，取得本發明之抗菌紙。 製造例3 以噚喹酸鈉之0.1〜5. 0%水溶液，將醫院所使 用之病歷原紙以填料壓製機於1 0 g/m 2塗布，取得本 發明之抗菌紙。 製造例4 本紙張尺度適用中國國家標準（CNS ) A4規格（210X297公釐） -----------C I 裝一Γ (請先閲讀背面之注意事項再填寫本頁) ，1T- 線 389809 經濟部中央標準局貝工消費合作社印製 A7 B7 五、發明説明（5 ) 於依製劑例2爲準所得之噚喹酸鈣之0.3〜5. 0 %分散液中配合以5%噴墨加工劑，並對記錄用紙原紙以 氣刀塗料器以1 5 g/m 2塗工，取得本發明之抗菌紙。 製造例5 於手抄紙片機抄紙試驗（依J I S P 8 2 0 9 )中 ，在抄紙時，以添加腭喹酸鈉之水溶液進行抄紙。噚喹酸 鈉之添加量，以對紙漿之比例爲1. 0〜5. 0%。抄紙 條件爲如下。 紙漿：LBKP 80/20 c s f : 4 0 0 毫升 坪量：1 0 0 g /m 2 熟化：105°Cx3分（熟化後之紙片於溫度23±1°C ，濕度5 5〜6 0之恆溫室中放置2 4小時後，作爲試驗 用試料。） 膠料劑：松香膠料（以A$20 3爲8%) 其次，示出抗菌試驗例。 試驗例1 將製造例1所得之本發明抗菌紙，依Hall oy ( J I S 一L 1902)，使用大腸桿菌0-16,金黃色葡萄 球菌209P，銅綠假單胞菌IFO 13275細菌進 行抗菌試驗。 使用皞睦酸鈉之5. 0%，3. 0%，1. 0%或 本紙張尺度適用中國國家標準（CNS ) A4規格（210X297公釐) ~ ' —-In — I — J裝-*--1--訂·「線 (請先閲讀背面之注意事項再填寫本頁) 389809 經濟部中央梂準局負工消費合作社印製 A7 B7五、發明説明（6 ) 0. 5%水溶液所得之抗菌紙，對上述3種細菌全部被確 認具充分的抗菌效果。 使用噚喹酸鈉之0. 1 %水溶液所得之抗菌紙，雖對 銅綠假單胞菌I FO 1 327 5之抗菌效果不夠充分， 但對大腸桿菌〇— 1 6及金黃色葡萄球菌2 0 9 P被確認 具充分的抗菌效果。 ， 試驗例2 對於製造例2所得之本發明抗菌紙，進行與試驗例1 同樣的試驗β其結果，使用噚晻酸鈣之4_ 0 % * 2 . 0 % > 1 . 0%或0. 5%分散液所得之抗菌紙，對上述3 種細菌全部被確認具充分的抗菌效果。 試驗例3 對於製造例3所得之本發明抗菌紙，進行與試驗例1 同樣的試驗。其結果，使用噚喹酸鈉之5.0%，3. 0 96 > 2 . 0%，1%，0. 5%或0. 3%水溶液所得之 抗菌紙，對上述3種細菌全部被確認具充分的抗菌效果。 使用噚喹酸鈉之0.1%水溶液所得之抗菌紙，雖對 銅綠假單胞菌I FO 1 3275之抗菌效果不夠充分， 但被確認對大腸桿菌及金黃色葡萄球菌具充分的抗菌效果 〇 試驗例4 ---------f 表 I*~ (請先閲讀背面之注意事項再填寫本頁) 本紙張尺度適用中國國家標準（CNS ) A4規格（210X297公釐） 9 S89809 A7 B7 經濟部中央樣準局負工消費合作社印製 五、發明説明（7 ) 對於製造例4所得之本發明抗菌紙，使用大腸桿菌〇 —1 6及金黃色葡萄球菌2 0 9 P進行與試驗1同樣之試 驗。使用曙喹酸鈣之0. 5%，3. 0%，1· 〇%， 0. 5%或0. 3%分散液所得之抗菌紙，均對2種細菌 ，被確認具充分的抗菌效果。 試驗例5 對於製造例5抄紙所得之本發明抗菌紙，進行與試驗 例1同樣之試驗。Df喹酸鈉之添加量（對紙漿％ ) 5 . 0 %，3. 0%或2. 0%之抗菌紙，均對上述3種細菌全 部被確認具充分的抗菌效果。 噚喹酸鈉之添加量（對紙漿％) 1· 〇%之抗菌紙’ 雖對銅綠假單胞菌I FO 1 3 2 7 5之抗菌效果不夠充 分，但對大腸桿菌〇— 1 6及金黃色葡萄球菌2 0 9 P被 確認且充分的抗菌效果。 〔發明之效果〕 本發明之抗菌紙具有優異的抗菌效力· ---------^ 裝 L— (請先閲讀背而之注意事項存填寫本頁) 訂 Γ: 線 本紙張尺度適用中國國家揲率（CNS ) A4規格（210X297公釐） 10 -Printed by the Central Standards Bureau, Ministry of Economic Affairs and Consumer Cooperatives A7 ____B7 _V. Description of the invention (1) [Technical Field to which the Invention belongs] The present invention relates to antibacterial paper, a method for producing antibacterial paper, an antibacterial treatment method for paper, and antibacterial for paper Agents [〔Problems to be Solved by the Invention] Nowadays, antibacterially treated paper is widely used. In the antibacterial treatment of paper, it is desirable to have papermaking treatment, coating or impregnating the base paper, and using antibacterial agent printing. Various treatment methods such as antibacterial treatment of ink printing, and development of antibacterial agents with antibacterial activity that can be applied to these various methods. [Means for Solving the Problems] To solve the above problems, the present invention provides 1) antibacterial paper treated with arsenic acid or the salt, and 2) antibacterial paper in which the paper is coated or impregnated with a liquid preparation containing arsenic acid or the salt. 3) A method for producing an antibacterial paper in which a dark acid or the salt is added to a paper dispersion during papermaking, 4) a paper coated or impregnated with a liquid preparation containing quinolinic acid or the salt 5) an antibacterial treatment method for paper printed on paper with a printing ink containing asleep acid or the salt, and 6) an antibacterial agent for paper containing quinolinic acid or the salt as an active ingredient. [Implementation Mode of the Invention] The quinolinic acid used in the present invention is a chemical name of 5-ethyl-5,8-dihydro-8-oxo [1,3] dioxo [4,5 —g 〕 Quine (Read the notes on the back and then fill out this page) Λ < Binding · Binding-___if This paper size is applicable to the Chinese national standard (CNS) A4 (210X297 mm) -4-A7 B7 Central Ministry of Economic Affairs Printed by the Task Force Consumers Cooperative, V. Description of Invention (2) Antibacterial compounds described in the Pesticide Manual, 10th Edition (published by the British Crop Protection Council), The Pesticide Manual, page 76. Any of the salts having antibacterial activity in the present invention, such as sodium, potassium, and other monovalent metal salts, ammonium salts, organic ammonium salts, and other monovalent salts, calcium salts, magnesium salts, and other alkaline earth metal salts and zinc salts , Aluminium salt and other two-valent gold tincture types can also be used. The paper used in the present invention is not particularly limited, and can be Japanese paper, Western paper, paperboard, pie, back to chess, temple, rent, rp. Letters, letters, office supplies, notes, etc. er set), report paper, information paper, carbonless paper, PPC paper, document paper, photo album paper, packaging paper, carton paper, hospital medical record paper and medicine bags, paper diapers, paper sheets, sanitary napkins, Tissue paper, agricultural seedling boxes, etc. can also be the object of the present invention. "There is no particular limitation on the treatment method of the rosin acid or the salt of the paper, but it is usually used in the form of alfalfa. The paper cloth is now taught the treatment method. The type of the liquid preparation can include solutions, emulsions, suspensions, etc. At this time, the concentration of the dark acid or the salt in the treatment liquid (liquid preparation) is generally 0. 0 1 0% by weight. In addition to the method of coating or impregnating paper using quinolinic acid or the salt, the method of antibacterial treatment of paper using quinolinic acid or the salt can be exemplified. Printing method, adding quinolinic acid or the salt to the dispersion of the paper during papermaking, etc. When printing paper with printing ink containing quinolinic acid or the salt, this paper size applies Chinese national standards ( CNS > Α4 Grid (210 × 297 mm) Please read the note on the back \ i \ [I; Binding-5-Printed on the A7 B7 by the Consumer Cooperatives of the Central Standards Bureau of the Ministry of Economic Affairs 5. In the description of the invention (3), for example, in advance The printing ink contains 0.01 to 5 percent of quinolinic acid or the salt, and the printing ink is spray-printed by inkjet printing. The antibacterial paper of the present invention is usually kept on the paper to make quinquine A sufficient amount of the acid or the salt to exhibit an antibacterial effect, for example, about 0.1 mg / m2 to 8 00 mg / m2 «B quinolinic acid or the lower limit of the salt content, preferably 2 mg / m2, more preferably 2 Omg / m2, more preferably about 6 Omg / m2, and the upper limit is preferably 400 Omg / m2, more preferably 200 Omg / m2, and even more preferably about 20 Omg / m2. Paper for Escherichia coli such as Escherichia coli, Staphylococcus aureus, Staphylococcus aureus, Pseudomonas aeruginosa, Pseudomonas fluorescens, etc., Proteus spp. , Bacillus subtilis, Enterobacter genus, Enterobacter aerogenes, Klebsiella pneumoniae, Serratia Bacteria and other bacteria have antibacterial effect. [Examples] Next, the present invention will be described in more detail with examples, but the present invention is not limited to the following examples. In other words, in the following examples, all the percentages represent weight%. First, the paper of the present invention used in the production of the antibacterial paper of the present invention, a preparation example using an antibacterial agent, and a preparation example 1 were added 10 g of sodium quinolinate to 90 g of water, and the paper was well stirred to obtain the paper. Standards are applicable to China National Standard (CNS) A4 (210X297 mm) ----- ^ ----- C tt-IΓ (Please read the note on the back before filling this page)-Order-Ministry of Economic Affairs Printed by the Central Standards Bureau ’s Consumer Cooperative 389809 at B7 V. Description of the invention (4) 10% solution. Formulation Example 2 10 g of calcium quinolinate was added to 200 ml of water, and stirred in a homogenizer at about 5000 rpm for 20 minutes. Next, DEMOL N (a dispersant manufactured by Kao Corporation) 2 was added. 2 G, and stirred for another minute to obtain a dispersion. Next, a production example of the antibacterial paper is shown. Production Example 1 Using a 0.1 to 5.0% aqueous solution of sodium quinolinate, both sides of the base paper of the document were coated with 20 g / m 2 to obtain the antibacterial paper of the present invention. Manufacturing Example 2 Based on Formulation Example 2, the 0.5 to 4.0 dispersion of sodium quinolinate was mixed with a coating colorant, and a high-quality paper was coated with an air knife coater at 16 g / m 2 Coated to obtain the antibacterial paper of the present invention. Production Example 3 A 0.1 to 5.0% aqueous solution of sodium quinolinate was used to coat a medical record base paper used in a hospital with a filler press at 10 g / m 2 to obtain an antibacterial paper of the present invention. Manufacturing Example 4 This paper size is in accordance with Chinese National Standard (CNS) A4 specification (210X297mm) ----------- CI Packing Γ (Please read the precautions on the back before filling this page), 1T -Line 389809 Printed by A7 B7, Shellfish Consumer Cooperative, Central Bureau of Standards, Ministry of Economic Affairs 5. Description of the invention (5) 0.3 ~ 5.0% of calcium quinolinate obtained according to Formulation Example 2 The inkjet processing agent was applied to a recording paper base paper with an air knife coater at 15 g / m 2 to obtain the antibacterial paper of the present invention. Production Example 5 In a papermaking test using a hand sheet machine (according to J I S P 829), papermaking was performed by adding an aqueous solution of sodium quinolinate during papermaking. 0%。 The amount of sodium quinolinate added to the pulp ratio is 1. 0 ~ 5. 0%. Papermaking conditions are as follows. Pulp: LBKP 80/20 csf: 4 0 0 milliliters per square meter: 10 0 g / m 2 curing: 105 ° Cx3 minutes (cured paper in a constant temperature room at 23 ± 1 ° C, humidity 5 5 ~ 60 After standing for 24 hours, it was used as a test sample.) Rubber agent: Rosin rubber (A $ 20 3 is 8%) Next, an antibacterial test example is shown. Test Example 1 The antibacterial paper of the present invention obtained in Manufacturing Example 1 was subjected to an antibacterial test according to Hall oy (J I S-L 1902) using E. coli 0-16, S. aureus 209P, and Pseudomonas aeruginosa IFO 13275 bacteria. Use 5.0%, 3.0%, 1.0% of sodium pentamate or this paper size is applicable to China National Standard (CNS) A4 specification (210X297 mm) ~ '—-In — I — J Pack-* --1--Order · "Line (please read the precautions on the back before filling this page) 389809 Printed A7 B7 by the Consumers' Cooperatives of the Central Government Bureau of the Ministry of Economic Affairs V. Description of the invention (6) 0. 5% aqueous solution The antibacterial paper has been confirmed to have sufficient antibacterial effect on all the above three kinds of bacteria. The antibacterial paper obtained by using 0.1% aqueous solution of sodium quinolinate, although the antibacterial effect on Pseudomonas aeruginosa I FO 1 327 5 is not enough It is sufficient, but it is confirmed that it has sufficient antibacterial effect on E. coli -16 and Staphylococcus aureus 209 P. Test Example 2 The same test as Test Example 1 was performed on the antibacterial paper of the present invention obtained in Manufacturing Example 2. As a result, the antibacterial paper obtained by using 4_ 0% * 2.0% > 1.0% or 0.5% dispersion of calcium arsenate was confirmed to have sufficient antibacterial effect on all of the above three kinds of bacteria. Test Example 3 The antibacterial paper of the present invention obtained in Production Example 3 was subjected to the same test as Test Example 1. As a result, 噚 was used. The antibacterial paper obtained from 5.0%, 3.096 > 2.0%, 1%, 0.5% or 0.3% aqueous solution of sodium quinate has been confirmed to have sufficient antibacterial effect on all the above three kinds of bacteria. The antibacterial paper obtained by using a 0.1% aqueous solution of sodium quinolinate has insufficient antibacterial effect on Pseudomonas aeruginosa I FO 1 3275, but it has been confirmed to have sufficient antibacterial effect on E. coli and Staphylococcus aureus. 4 --------- f Table I * ~ (Please read the notes on the back before filling in this page) This paper size is applicable to China National Standard (CNS) A4 specification (210X297 mm) 9 S89809 A7 B7 Economy Printed by the Central Bureau of Prototype and Consumer Cooperatives 5. Description of the invention (7) For the antibacterial paper of the present invention obtained in Manufacturing Example 4, E. coli 0-16 and Staphylococcus aureus 2 0 9 P were used to perform the same test 1 The test. The antibacterial paper obtained by using 0.5%, 3.0%, 1.0%, 0.5%, or 0.3% dispersion of calcium quinolinate was confirmed to be sufficient for 2 kinds of bacteria. Test Example 5 The same test as in Test Example 1 was performed on the antibacterial paper of the present invention obtained from the papermaking process of Manufacturing Example 5. Dfquine The added amount of sodium (% of pulp) 5.0%, 3.0% or 2.0% of antibacterial paper, all of them have been confirmed to have sufficient antibacterial effect on all three kinds of bacteria. Addition of sodium quinoline ( For pulp%) 1. 0% of antibacterial paper 'Although the antibacterial effect on Pseudomonas aeruginosa I FO 1 3 2 7 5 is not sufficient, it is effective for E. coli 16 and Staphylococcus aureus 2 0 9 P Confirmed and sufficient antibacterial effect. [Effects of the Invention] The antibacterial paper of the present invention has excellent antibacterial efficacy. --------- ^ Packing L— (Please read the precautions on the back and fill in this page) Order Γ: Thread paper size Applicable to China National Standard (CNS) A4 specification (210X297 mm) 10-