TW351720B - Asialotrisaccharide moranoline derivatives and drugs - Google Patents

Asialotrisaccharide moranoline derivatives and drugs

Info

Publication number
TW351720B
TW351720B TW086108722A TW86108722A TW351720B TW 351720 B TW351720 B TW 351720B TW 086108722 A TW086108722 A TW 086108722A TW 86108722 A TW86108722 A TW 86108722A TW 351720 B TW351720 B TW 351720B
Authority
TW
Taiwan
Prior art keywords
integer
asialotrisaccharide
formula
drugs
galactopyranosyl
Prior art date
Application number
TW086108722A
Other languages
Chinese (zh)
Inventor
Tadaaki Ohgi
Kouichi Ishiyama
Kazuya Mori
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Application granted granted Critical
Publication of TW351720B publication Critical patent/TW351720B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

A formula indicated below presents a novel asialotrisaccharide moranoline derivative or their pharmaceutically acceptable metal salts: where R represents formula (a) or formula (b), R1 and R2 represent galactopyranosyl or all or some of hydroxy group of which any group will substitute galactopyranosyl; while other represents fucopyranosyl; A represents -(CH2)m-.-(CH2)n-Nre-CO-O-.-CO-O-.-(CH2)n -CO-)- or -C2H4 (OC2H4)y-OCH2-CO-O-; Ra and Rb are the same or different and each represent a saturated or unsaturated fatty hydrocarbon group, or a saturated or unsaturated fatty residue; Rc and Rd are the same or different, and each represents hydroxy, alkyl, or alkoxy; and Re represents H or alkyl; m is an integer of 0-12; n, an integer of 2-12, y, an integer of 0-3 and z integer of 1-4.
TW086108722A 1996-06-17 1997-08-27 Asialotrisaccharide moranoline derivatives and drugs TW351720B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP15580196 1996-06-17
JP10341997 1997-04-21

Publications (1)

Publication Number Publication Date
TW351720B true TW351720B (en) 1999-02-01

Family

ID=26444054

Family Applications (1)

Application Number Title Priority Date Filing Date
TW086108722A TW351720B (en) 1996-06-17 1997-08-27 Asialotrisaccharide moranoline derivatives and drugs

Country Status (3)

Country Link
AU (1) AU3107497A (en)
TW (1) TW351720B (en)
WO (1) WO1997048712A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998051315A1 (en) * 1997-05-12 1998-11-19 Nippon Shinyaku Co., Ltd. Therapeutic agent for articular rheumatism
WO2008096690A1 (en) * 2007-02-05 2008-08-14 Nippon Shinyaku Co., Ltd. Polyethylene glycol derivative
US20110200582A1 (en) 2009-12-23 2011-08-18 Novartis Ag Lipids, lipid compositions, and methods of using them
EP3167889B1 (en) * 2014-07-11 2020-12-16 Tokyo University of Science Foundation Dendritic cell immune receptor activators for use in therapy
US10342761B2 (en) 2014-07-16 2019-07-09 Novartis Ag Method of encapsulating a nucleic acid in a lipid nanoparticle host
JP6826014B2 (en) * 2017-09-13 2021-02-03 株式会社東芝 Compositions and kits containing biodegradable compounds, lipid particles, lipid particles

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997000881A1 (en) * 1995-06-22 1997-01-09 Nippon Shinyaku Co., Ltd. Moranoline derivatives

Also Published As

Publication number Publication date
AU3107497A (en) 1998-01-07
WO1997048712A1 (en) 1997-12-24

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