WO1998051315A1 - Therapeutic agent for articular rheumatism - Google Patents

Therapeutic agent for articular rheumatism Download PDF

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Publication number
WO1998051315A1
WO1998051315A1 PCT/JP1998/002061 JP9802061W WO9851315A1 WO 1998051315 A1 WO1998051315 A1 WO 1998051315A1 JP 9802061 W JP9802061 W JP 9802061W WO 9851315 A1 WO9851315 A1 WO 9851315A1
Authority
WO
WIPO (PCT)
Prior art keywords
articular rheumatism
therapeutic agent
formulae
integer
different
Prior art date
Application number
PCT/JP1998/002061
Other languages
French (fr)
Japanese (ja)
Inventor
Yoji Ezure
Shigeaki Maruo
Hirotsugu Ogawa
Original Assignee
Nippon Shinyaku Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co., Ltd. filed Critical Nippon Shinyaku Co., Ltd.
Publication of WO1998051315A1 publication Critical patent/WO1998051315A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom

Abstract

An articular rheumatism remedy which is an asialotrisaccharic moranoline derivative represented by general formula [I] or a pharmacologically acceptable salt thereof, wherein -A- represents -(CH2)m-, -(CH2)n-NRe-CO-O-, -CO-O-, -(CH¿2?)n-CO-O-, or -(CH2)n-O- (wherein R?e¿ represents hydrogen or lower alkyl; m is an integer of 0 to 12; and n is an integer of 2 to 12); R represents formulae (A) or (B) wherein R?a and Rb¿ may be the same or different and each represents an (un)saturated aliphatic hydrocarbon group or an (un)saturated acyl; and one of R?1 and R2¿ represents either galactopyranosyl in which optionally all or part of the hydrogen atoms of the hydroxyl groups have been replaced with any of formulae (C) and (D) and the other represents fucopyranosyl, provided that R?c and Rd¿ may be the same or different and each represents alkyl or hydroxy.
PCT/JP1998/002061 1997-05-12 1998-05-08 Therapeutic agent for articular rheumatism WO1998051315A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9/121244 1997-05-12
JP12124497 1997-05-12

Publications (1)

Publication Number Publication Date
WO1998051315A1 true WO1998051315A1 (en) 1998-11-19

Family

ID=14806476

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP1998/002061 WO1998051315A1 (en) 1997-05-12 1998-05-08 Therapeutic agent for articular rheumatism

Country Status (1)

Country Link
WO (1) WO1998051315A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010048955A1 (en) * 2008-10-30 2010-05-06 Hyben Vital Licens Aps Composition comprising a glycoside of a mono- or diacyiglycerol compound and an oil rich in n-3 polyunsaturated fatty acids, a method of producing the composition and use of the composition

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995026970A1 (en) * 1994-04-01 1995-10-12 Nippon Shinyaku Co., Ltd. Moranoline derivative
WO1997000881A1 (en) * 1995-06-22 1997-01-09 Nippon Shinyaku Co., Ltd. Moranoline derivatives
WO1997002278A1 (en) * 1995-06-30 1997-01-23 Nippon Shinyaku Co., Ltd. Sugar chain derivatives and process for producing the same
WO1997048712A1 (en) * 1996-06-17 1997-12-24 Nippon Shinyaku Co., Ltd. Asialotrisaccharide moranoline derivatives and drugs

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995026970A1 (en) * 1994-04-01 1995-10-12 Nippon Shinyaku Co., Ltd. Moranoline derivative
WO1997000881A1 (en) * 1995-06-22 1997-01-09 Nippon Shinyaku Co., Ltd. Moranoline derivatives
WO1997002278A1 (en) * 1995-06-30 1997-01-23 Nippon Shinyaku Co., Ltd. Sugar chain derivatives and process for producing the same
WO1997048712A1 (en) * 1996-06-17 1997-12-24 Nippon Shinyaku Co., Ltd. Asialotrisaccharide moranoline derivatives and drugs

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010048955A1 (en) * 2008-10-30 2010-05-06 Hyben Vital Licens Aps Composition comprising a glycoside of a mono- or diacyiglycerol compound and an oil rich in n-3 polyunsaturated fatty acids, a method of producing the composition and use of the composition

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