TW224970B - - Google Patents

Info

Publication number
TW224970B
TW224970B TW081107688A TW81107688A TW224970B TW 224970 B TW224970 B TW 224970B TW 081107688 A TW081107688 A TW 081107688A TW 81107688 A TW81107688 A TW 81107688A TW 224970 B TW224970 B TW 224970B
Authority
TW
Taiwan
Prior art keywords
benzopyrans
intermediates
preparation
free
certain
Prior art date
Application number
TW081107688A
Other languages
English (en)
Chinese (zh)
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of TW224970B publication Critical patent/TW224970B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C07F9/65522Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Inspection Of Paper Currency And Valuable Securities (AREA)
  • Cosmetics (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Noodles (AREA)
  • Credit Cards Or The Like (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Fire-Detection Mechanisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TW081107688A 1991-10-02 1992-09-29 TW224970B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91402630A EP0535283A1 (en) 1991-10-02 1991-10-02 Cardioprotective tocopherol analogs

Publications (1)

Publication Number Publication Date
TW224970B true TW224970B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1994-06-11

Family

ID=8208620

Family Applications (1)

Application Number Title Priority Date Filing Date
TW081107688A TW224970B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1991-10-02 1992-09-29

Country Status (17)

Country Link
EP (2) EP0535283A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP3230699B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100253108B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE163421T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU652077B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2079289C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69224501T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0536036T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2115656T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI105552B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3026242T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU215123B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL103305A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO923840L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ244549A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW224970B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA927429B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5510373A (en) * 1992-04-06 1996-04-23 Merrell Pharmaceuticals Inc. Cardioprotective agents
US5721233A (en) * 1992-04-06 1998-02-24 Merrell Pharmaceuticals Inc. Derivatives of 2,3-dihydro benzofuranols
US5545660A (en) * 1992-04-07 1996-08-13 Merrell Pharmaceuticals Inc. Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans
PT1047701E (pt) * 1997-11-25 2005-10-31 Antipodean Biotechnology Ltd Antioxidantes direccionados para as mitocondrias
AUPR549901A0 (en) 2001-06-06 2001-07-12 Vital Health Sciences Pty Ltd Topical formulation containing tocopheryl phosphates
EP1420797A4 (en) 2001-07-27 2005-03-02 Vital Health Sciences Pty Ltd DERMAL THERAPY USING PHOSPHATE DERIVATIVES OF ELECTRONIC TRANSFER AGENTS
DE50212837D1 (de) * 2002-06-19 2008-11-13 Cognis Ip Man Gmbh Verwendung von Wirkstoffgemischen zur Herstellung eines Medikamentes gegen rheumatische Arthritis
AU2002950713A0 (en) 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
US7888334B2 (en) 2003-08-22 2011-02-15 Antipodean Pharmaceuticals, Inc. Mitoquinone derivatives used as mitochondrially targeted antioxidants
CN1839142B (zh) 2003-08-22 2010-06-16 澳新制药公司 用作靶向线粒体的抗氧化剂的线粒体醌衍生物
CA2580584C (en) 2003-09-19 2015-07-28 Galileo Pharmaceuticals, Inc. Use of alpha-tocotrienol for treatment of mitochondrial diseases
JP4847437B2 (ja) 2004-03-03 2011-12-28 バイタル ヘルス サイエンシズ プロプライアタリー リミティド アルカロイド製剤
US9168216B2 (en) 2005-06-17 2015-10-27 Vital Health Sciences Pty. Ltd. Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
US7813042B2 (en) 2005-09-12 2010-10-12 Sharp Kabushiki Kaisha Multiple-view directional display
JP4933553B2 (ja) 2006-09-07 2012-05-16 シャープ株式会社 画像表示装置、電子機器およびパララックスバリア素子
WO2011094814A1 (en) 2010-02-05 2011-08-11 Phosphagenics Limited Carrier comprising non-neutralised tocopheryl phosphate
CA2794734C (en) 2010-03-30 2017-12-12 Phosphagenics Limited Transdermal delivery patch
US9561243B2 (en) 2011-03-15 2017-02-07 Phosphagenics Limited Composition comprising non-neutralised tocol phosphate and a vitamin A compound
JP6882321B2 (ja) 2015-12-09 2021-06-02 フォスファージニクス リミテッド 医薬製剤
EP3558903B1 (en) 2016-12-21 2024-07-03 Avecho Biotechnology Limited Process for phosphorylating a complex alcohol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62205091A (ja) * 1986-03-04 1987-09-09 Senjiyu Seiyaku Kk 新規なリン酸ジエステルならびにその塩、その製造法およびそれを含有する製剤
CA2002649C (en) * 1988-11-14 2000-06-06 Margaret Petty Cardioprotective tocopherol analogs
US5500444A (en) 1989-11-14 1996-03-19 Hoechst Marion Roussel, Inc. Cardioprotective tocopherol analogs
US5135945A (en) 1991-06-05 1992-08-04 Merrell Dow Pharmaceuticals Inc. Cholesterol-lowering tocopherol analogs

Also Published As

Publication number Publication date
ZA927429B (en) 1993-04-07
IL103305A0 (en) 1993-02-21
AU652077B2 (en) 1994-08-11
NO923840L (no) 1993-04-05
FI924424L (fi) 1993-04-03
ATE163421T1 (de) 1998-03-15
NO923840D0 (no) 1992-10-01
ES2115656T3 (es) 1998-07-01
HU215123B (hu) 1998-09-28
JP3230699B2 (ja) 2001-11-19
FI105552B (fi) 2000-09-15
GR3026242T3 (en) 1998-05-29
EP0536036A1 (en) 1993-04-07
CA2079289A1 (en) 1993-04-03
DE69224501T2 (de) 1998-06-25
EP0536036B1 (en) 1998-02-25
AU2538392A (en) 1993-04-08
JPH05310763A (ja) 1993-11-22
DK0536036T3 (da) 1998-03-16
FI924424A0 (fi) 1992-10-01
EP0535283A1 (en) 1993-04-07
HUT62592A (en) 1993-05-28
NZ244549A (en) 1994-07-26
KR100253108B1 (ko) 2000-05-01
DE69224501D1 (de) 1998-04-02
CA2079289C (en) 2003-02-18
HU9203134D0 (en) 1992-12-28

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