TW202537625A - 使用布魯頓酪胺酸激酶抑制劑治療慢性自發性蕁麻疹之方法 - Google Patents

使用布魯頓酪胺酸激酶抑制劑治療慢性自發性蕁麻疹之方法

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Publication number
TW202537625A
TW202537625A TW113146310A TW113146310A TW202537625A TW 202537625 A TW202537625 A TW 202537625A TW 113146310 A TW113146310 A TW 113146310A TW 113146310 A TW113146310 A TW 113146310A TW 202537625 A TW202537625 A TW 202537625A
Authority
TW
Taiwan
Prior art keywords
compound
formula
pharmaceutically acceptable
acceptable salt
treatment
Prior art date
Application number
TW113146310A
Other languages
English (en)
Chinese (zh)
Inventor
索維克 巴塔查亞
布魯諾 比斯
麥西 卡班斯基
布魯諾 塞尼
巴克 史蒂芬 德
馬丁 卡爾
亞文 金西卡
安德里亞納 拉迪沃維奇
湯瑪士 塞弗林
朱利安 斯托里姆
加拉米 亞歷山大 維塔利蒂
Original Assignee
瑞士商諾華公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 瑞士商諾華公司 filed Critical 瑞士商諾華公司
Publication of TW202537625A publication Critical patent/TW202537625A/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW113146310A 2019-05-23 2020-05-21 使用布魯頓酪胺酸激酶抑制劑治療慢性自發性蕁麻疹之方法 TW202537625A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962851996P 2019-05-23 2019-05-23
US62/851,996 2019-05-23

Publications (1)

Publication Number Publication Date
TW202537625A true TW202537625A (zh) 2025-10-01

Family

ID=70918751

Family Applications (2)

Application Number Title Priority Date Filing Date
TW113146310A TW202537625A (zh) 2019-05-23 2020-05-21 使用布魯頓酪胺酸激酶抑制劑治療慢性自發性蕁麻疹之方法
TW109116854A TWI868139B (zh) 2019-05-23 2020-05-21 使用布魯頓酪胺酸激酶抑制劑治療慢性自發性蕁麻疹之方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW109116854A TWI868139B (zh) 2019-05-23 2020-05-21 使用布魯頓酪胺酸激酶抑制劑治療慢性自發性蕁麻疹之方法

Country Status (22)

Country Link
US (2) US12419889B2 (https=)
EP (2) EP4599894A3 (https=)
JP (2) JP7568651B2 (https=)
KR (1) KR20220012281A (https=)
CN (1) CN113795255A (https=)
AU (2) AU2020280272B2 (https=)
BR (1) BR112021022602A2 (https=)
CA (1) CA3138081A1 (https=)
CL (1) CL2021003032A1 (https=)
DK (1) DK3972604T3 (https=)
ES (1) ES3039974T3 (https=)
FI (1) FI3972604T3 (https=)
HR (1) HRP20251001T1 (https=)
IL (1) IL286983B2 (https=)
LT (1) LT3972604T (https=)
MX (2) MX2021013942A (https=)
PL (1) PL3972604T3 (https=)
PT (1) PT3972604T (https=)
RS (1) RS67141B1 (https=)
SI (1) SI3972604T1 (https=)
TW (2) TW202537625A (https=)
WO (1) WO2020234782A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS67141B1 (sr) 2019-05-23 2025-09-30 Novartis Ag Inhibitor brutonove tirozin kinaze za upotrebu u lečenju hronične spontane urtikarije
JP7564347B2 (ja) 2021-09-03 2024-10-08 ノバルティス アーゲー 多発性硬化症を治療するためのｌｏｕ０６４
US20250032488A1 (en) 2021-12-14 2025-01-30 Novartis Ag Methods of treatment using lou064
TW202342048A (zh) 2022-02-28 2023-11-01 瑞士商諾華公司 使用ｌｏｕ０６４治療化膿性汗腺炎之方法
KR102834740B1 (ko) * 2023-04-10 2025-07-17 아주대학교산학협력단 Hsp10 또는 이의 항체를 유효성분으로 포함하는 만성 자발적 두드러기의 진단을 위한 바이오마커 조성물
WO2024235163A1 (zh) * 2023-05-12 2024-11-21 武汉人福创新药物研发中心有限公司 Btk抑制剂的用途和单剂量药物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2705719C (en) 2007-09-14 2016-10-11 Janssen Pharmaceutica N.V. Thieno-and furo-pyrimidine modulators of the histamine h4 receptor
US9512084B2 (en) * 2013-11-29 2016-12-06 Novartis Ag Amino pyrimidine derivatives
EP3092250A4 (en) 2014-01-08 2017-05-24 Moderna Therapeutics, Inc. Polynucleotides for the in vivo production of antibodies
WO2016079669A1 (en) * 2014-11-19 2016-05-26 Novartis Ag Labeled amino pyrimidine derivatives
RS67141B1 (sr) 2019-05-23 2025-09-30 Novartis Ag Inhibitor brutonove tirozin kinaze za upotrebu u lečenju hronične spontane urtikarije

Also Published As

Publication number Publication date
TWI868139B (zh) 2025-01-01
SI3972604T1 (sl) 2025-09-30
US20220184074A1 (en) 2022-06-16
RS67141B1 (sr) 2025-09-30
KR20220012281A (ko) 2022-02-03
MX2021013942A (es) 2022-01-04
EP3972604B1 (en) 2025-06-04
CN113795255A (zh) 2021-12-14
EP4599894A2 (en) 2025-08-13
PT3972604T (pt) 2025-08-26
TW202110450A (zh) 2021-03-16
AU2025252618A1 (en) 2025-11-06
AU2020280272A1 (en) 2021-11-18
EP3972604A1 (en) 2022-03-30
JP2024178168A (ja) 2024-12-24
AU2020280272B2 (en) 2025-07-24
EP4599894A3 (en) 2025-11-12
DK3972604T3 (da) 2025-09-15
BR112021022602A2 (pt) 2022-01-04
CA3138081A1 (en) 2020-11-26
MX2024014626A (es) 2025-01-09
CL2021003032A1 (es) 2022-09-09
IL286983B2 (en) 2026-01-01
JP2022533981A (ja) 2022-07-27
LT3972604T (lt) 2025-09-10
WO2020234782A1 (en) 2020-11-26
JP7568651B2 (ja) 2024-10-16
IL286983B1 (en) 2025-09-01
HRP20251001T1 (hr) 2025-10-24
IL286983A (en) 2021-12-01
ES3039974T3 (en) 2025-10-28
FI3972604T3 (fi) 2025-09-01
PL3972604T3 (pl) 2025-09-22
US12419889B2 (en) 2025-09-23
US20250375446A1 (en) 2025-12-11

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