TW202404982A - Mci-1拮抗劑之無定形及結晶形式 - Google Patents
Mci-1拮抗劑之無定形及結晶形式 Download PDFInfo
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- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
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- 239000013002 intravenous (IV) drug Substances 0.000 description 1
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- 235000019359 magnesium stearate Nutrition 0.000 description 1
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- 210000001700 mitochondrial membrane Anatomy 0.000 description 1
- 238000001565 modulated differential scanning calorimetry Methods 0.000 description 1
- 210000004985 myeloid-derived suppressor cell Anatomy 0.000 description 1
- 238000000655 nuclear magnetic resonance spectrum Methods 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- NKBWPOSQERPBFI-UHFFFAOYSA-N octadecyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCCCCCC NKBWPOSQERPBFI-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263327656P | 2022-04-05 | 2022-04-05 | |
| US63/327,656 | 2022-04-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW202404982A true TW202404982A (zh) | 2024-02-01 |
Family
ID=86386948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW112112761A TW202404982A (zh) | 2022-04-05 | 2023-04-06 | Mci-1拮抗劑之無定形及結晶形式 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240140966A1 (enExample) |
| EP (1) | EP4504738A1 (enExample) |
| JP (1) | JP2025511331A (enExample) |
| AU (1) | AU2023250874A1 (enExample) |
| CA (1) | CA3255077A1 (enExample) |
| MX (1) | MX2024012195A (enExample) |
| TW (1) | TW202404982A (enExample) |
| UY (1) | UY40218A (enExample) |
| WO (1) | WO2023196361A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4519271A1 (en) | 2022-05-04 | 2025-03-12 | Gilead Sciences, Inc. | Salts and polymorphs of certain mcl-1 inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3474B1 (ar) | 2014-08-29 | 2020-07-05 | Amgen Inc | مشتقات تيتراهيدرونافثالين التي تثبط بروتين mcl-1 |
| KR20230113577A (ko) * | 2020-11-25 | 2023-07-31 | 암젠 인크 | 알데히드의 거울상이성질체 선택적 알케닐화 |
-
2023
- 2023-04-05 WO PCT/US2023/017505 patent/WO2023196361A1/en not_active Ceased
- 2023-04-05 AU AU2023250874A patent/AU2023250874A1/en active Pending
- 2023-04-05 EP EP23724439.7A patent/EP4504738A1/en active Pending
- 2023-04-05 JP JP2024558382A patent/JP2025511331A/ja active Pending
- 2023-04-05 CA CA3255077A patent/CA3255077A1/en active Pending
- 2023-04-05 US US18/296,211 patent/US20240140966A1/en active Pending
- 2023-04-06 TW TW112112761A patent/TW202404982A/zh unknown
- 2023-04-10 UY UY0001040218A patent/UY40218A/es unknown
-
2024
- 2024-10-02 MX MX2024012195A patent/MX2024012195A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20240140966A1 (en) | 2024-05-02 |
| CA3255077A1 (en) | 2023-10-12 |
| WO2023196361A1 (en) | 2023-10-12 |
| MX2024012195A (es) | 2024-11-08 |
| EP4504738A1 (en) | 2025-02-12 |
| JP2025511331A (ja) | 2025-04-15 |
| AU2023250874A1 (en) | 2024-10-10 |
| UY40218A (es) | 2023-10-13 |
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