TW202400117A - Laser enhancer composition for improving spots, wrinkles, elasticity, pores and acne - Google Patents

Abstract

The present invention is characterized in that: as the composition used to remove the keratin (1) of the epidermal layer (2) via the laser skin peeling treatment, the composition (10) smeared on the epidermal layer (2) to perform treatment is formed; the composition (10) uses one or more mixtures of the skin peeling part (11a) capable of realizing the skin peeling and the conducting part (12) capable of realizing the heat conduction to avoid the damage and the fume generation due to laser; by the viscous part (12) using the help of viscosity to mix the skin peeling part (11a) and the conducting part (11b), the mix and mixture formation of volatile ethanol (13) and purified distilled water can be realized. Namely, the present invention is related to a laser enhancer composition used for improving chlosama, winkles, elasticity, pores and acne. In particular, the present invention can reduce or prevent the carbon damage and the generation of fine-sized fume due to high laser power output during a carbon enhancer laser treatment on the epidermal layer, thereby protecting not only the health of a doctor performing the treatment, but also the health of a patient receiving the treatment and further preventing the generation of the fumes in the form of fine dust, so as to reduce environmental pollution, avoid the occurrence of unpleasant odors like burning odors due to laser, complete the laser treatment more comfortably and delightly, use heat conduction to improve chloasmas, wrinkles, elasticity and pores on the basis of the skin peeling, and maximize the laser effect while performing wrinkle laser treatment.

Description

Laser enhancer composition for improving melasma, wrinkles, elasticity, pores and acne

The present invention relates to a laser enhancer composition for improving chloasma, wrinkles, elasticity, pores and acne. In particular, it relates to a laser enhancer composition that can reduce or prevent excessive laser output when performing carbon enhancer laser treatment on the epidermis. It causes the destruction of carbon and the generation of fine-sized smoke (fume), thereby ensuring the health of the doctor who performs the treatment and the health of the patients receiving treatment, and furthermore, it can prevent the generation of fine dust or fume, thus reducing environmental pollution. In addition, it can prevent the occurrence of unpleasant odors such as burning smell caused by laser, making the treatment more comfortable and enjoyable. It can also be used to improve chloasma, wrinkles, elasticity, and pores through heat transfer in addition to peeling. and the development of enhancers that maximize the laser effect during laser treatment of wrinkles.

This patent application was supported by the Bioactive Agents Global Competitiveness Enhancement Project (B0080707000918) of the Ministry of Trade, Industry and Energy (MOTIE) and the Korea Institute of Industrial Technology (KIAT).

Generally speaking, laser treatments performed for cosmetic purposes are also called carbon laser peeling and laser soft peeling. The treatment described above is to apply laser intensifier carbon to the patient's face and then use microsecond pulse width laser (Q-switched Nd: TAG laser) to deliver laser energy and treat it so that it becomes entangled with the cuticle. The carbon is detached, thereby removing unnecessary exfoliation while delivering the heat generated by laser energy to the skin, thereby improving the treatment of chloasma, pores, elasticity and acne.

However, when the laser intensifier, carbon, receives laser energy, it is destroyed and generates fine-sized fume. The smoke may induce cancer or cause a decrease in lung function in the human body when inhaled, and may induce skin tumors when carbon is applied to the skin.

References 1) Morfeld P and McCunney RJ, (2009). Carbon Black and lung cancer testing a novel exposure metric by multi-model inference. Am. J . Ind. Med. 52 : 890-899.

Reference 2) Harber P, Muranko H, Solis S, Torossian A, Merz B. (2003) Effect of carbon black exposure on respiratory function and symptoms.

Reference 3) J. Occup. Env. Med. 45: 144-55. ILSI Risk Science Institute Workshop: The Relevance of the Rat Lung Response to Particle to Particle Overload for Human Risk Assessment Correlation between lung response to particles and particle overload).

Reference 4) Inh. Toxicol. 12: 1-17 (2000). International Agency for Research on Cancer: IARC Monographs on the Evaluation of Carcinogenic Risks to Humans (IARC paper on the Evaluation of Carcinogenic Risks to Humans) (2010), Vol. 93, February 1-14, 2006, Carbon Black, Titanium Dioxide, and Talc. Lyon

In order to prevent the inhalation of the smoke, it is currently necessary for the treating physician to hold a separate inhaler and inhale the generated smoke while using a laser to remove the carbon, or for a separate nurse to assist in inhaling the smoke. treatment at the same time. However, the effect of the smoke removal operation as described above is not perfect, which may not only cause health problems for the treatment practitioners, that is, doctors or nurses, and the persons being treated, but may also lead to potential environmental pollution.

As an example, Korean Registered Patent No. 1446706 discloses that "a compound containing fibroblast growth factor-9 (fibroblast growth factor-9) as an active ingredient for application to skin pre-treated with a carbon enhancer and then subjected to laser treatment" factor-9), a cosmetic composition for skin regeneration with a wavelength of 10,300 to 10,900 nm during laser treatment."

However, although the above-mentioned cosmetic composition for skin regeneration is a cosmetic composition for skin regeneration by laser treatment, since fine smoke is generated when the laser treatment is performed in a state containing carbon, separate inhalation is required. The device can completely remove the detached carbon and cutin, but the removal process is not simple, making it difficult to ensure the safety of the conscious and respiratory systems of everyone around during the treatment, such as patients and nurses. [Prior technical literature]

(Patent document 0001) Korean registered patent No. 1446706 "Cosmetic composition for skin regeneration"

The present invention aims to solve the existing problems as described above. The purpose of the present invention is to provide a method that can reduce or prevent the generation of fine-sized fume when performing laser peeling treatment on the epidermis, thereby ensuring the safety of the physician who performs the treatment. Health and the health of patients undergoing treatment can also prevent the generation of fine dust or smoke, thereby reducing environmental pollution, and can prevent the occurrence of unpleasant odors such as burning smell due to laser, making it more comfortable and enjoyable. After completing the treatment, a laser intensifier can also be used to maximize the effects of whitening, melasma improvement, wrinkles, acne, pore reduction, and exfoliation through heat transfer on the basis of peeling.

In order to achieve the above object, the present invention is characterized in that, as a composition for exfoliating the epidermal layer by laser treatment, a composition can be applied to the epidermal layer for treatment, and the use of the composition can be carried out One or more mixtures of the peeling part treated by laser and the conductive part that can achieve heat conduction, so as to avoid being damaged by the laser and generating smoke, and by mixing the peeling part and the conductive part with the help of viscosity The viscous part, ethanol that can be volatilized, and purified distilled water are mixed with each other to form.

At this time, the present invention is characterized in that the peeling part of the composition uses diamond in the form of a powder of a certain size that can easily remove cuticles, and the conductive part uses a magnetic body in the form of a powder of a certain size that can achieve heat conduction. One or more mixtures of gold and platinum.

In addition, the present invention is characterized in that the peeling part and the conduction part are formed with a particle size of 1 to 5㎛ that can be effectively absorbed between the cuticles in order to maximize the peeling and heat conduction effects.

In addition, the present invention is characterized in that the magnetic body of the transmission part uses one of the group consisting of Pt, Pd, Ag, Cu and Au or a mixture of one or more metal substances; and the magnetic substance consists of Co, Mn, Fe, Ni , Gd, Mo, MM'2O4 and MxOy (M and M' are each independently Co, Fe, Ni, Mn, Zn, Gd or Cr, 0 < x ≤3, 0 < y ≤5). A magnetic substance or a magnetic alloy selected from the group consisting of CoCu, CoPt, FePt, CoSm, NiFe and NiFeCo.

Furthermore, the present invention is characterized in that the viscous portion of the conductive portion uses methylcellulose.

In addition, the present invention is characterized in that the composition consists of 1 to 3 wt% of one or more of the peeling part and the conductive part, 1 to 3 wt% of the viscous part, 43 to 50 wt% of ethanol, and 45 to 45 wt% of the conductive part. Composed of 55wt% distilled water.

In addition, the terms or words used in this specification and the patent application scope of the invention should not be limited to their common or dictionary meanings, but should be based on the meaning that the inventor can use to describe his invention in the best way. The principle of appropriately defining the concepts of terms shall be explained in accordance with the meanings and concepts consistent with the technical idea of the present invention. Therefore, the embodiments described in this specification and the configurations illustrated in the drawings are only a preferred embodiment of the present invention and do not represent all the technical ideas of the present invention. It should be understood that there may be differences at the time of filing this application. There are many alternative equivalents and variations.

As described in the above constitution and function, the present invention relates to a laser enhancer composition for improving chloasma, wrinkles, elasticity, pores and acne. In particular, it can reduce or Preventing the destruction of carbon and the generation of fine-sized smoke (fume) due to excessive laser output, thereby ensuring the health of the doctor who performs the treatment and the health of the patient receiving treatment, and furthermore, preventing the formation of fine dust or fume. generation, thereby reducing environmental pollution, and preventing the occurrence of unpleasant odors such as burning smell due to laser, making the treatment more comfortable and pleasant, and can also be used to improve yellowing through heat transfer in addition to peeling. Maximizes the laser effect during laser treatment of spots, wrinkles, elasticity, pores and wrinkles.

Next, the preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings.

The present invention relates to a cream for removing cutin 1 in the epidermis layer 2 through laser peeling treatment, forming a composition 10 that can be treated by being applied to the epidermis layer 2. Its main components include a peeling part 11a and a conductive part 11b. , viscous part 12, ethanol 13 and distilled water 14.

The peeling part 11a of the present invention can achieve peeling, and the conductive part 11b can achieve heat conduction. The peeling part 11a and the conductive part 11b are formed of the composition 10 in order to remove the cutin 1 of the epidermal layer 2, and will not be destroyed by the laser 3 and will not generate fume. The peeling part 11a and the conductive part 11b included in the composition 10 can play their respective roles. The peeling part 11a can play a role for the doctor to perform peeling treatment on the face of the person being treated through the laser 3, and the conductive part 11b It can serve to transfer heat to the epidermal layer 2 when the doctor performs heating by the laser 3 . This can be selected according to the facial condition of the person being treated. As will be described later, the peeling part 11a and the conductive part 11b can also be used at the same time. Regarding the peeling part 11a and the conductive part 11b, when laser 3 treatment was performed using carbon in the past, the carbon would be cracked and torn due to heat, and fine-sized fumes would be generated in the air in which the treatment was performed. ), thus causing major problems such as inducing cancer and other respiratory diseases when inhaled into the respiratory systems of doctors, nurses and patients. However, even when the peeling part 11a and the conductive part 11b of the present invention are treated with the laser 3, the peeling part 11a and the conductive part 11b can be prevented from being broken due to heat, thereby preventing the generation of fine-sized fume. and ensure the safety of treatment.

At this time, the peeling part 11a of the composition 10 uses diamond formed in a powder form of a certain size that can easily remove cuticles, and the conductive part 11b uses a magnetic body formed in a powder form of a certain size that can achieve heat conduction. One or more mixtures of gold and platinum. In the structure of the composition 10 , the peeling part 11 a and the conductive part 11 b can each play different roles, and the peeling part 11 a can play a role for the doctor to use the laser 3 to perform peeling treatment on the face of the person being treated. , and the conductive portion 11b can play a role in transmitting heat to the epidermal layer 2 and promoting collagen synthesis in the tissue when the doctor performs heating by the laser 3. The peeling part 11a uses diamond that can achieve peeling effect, and the conductive part 11b uses magnetic material, gold and platinum that can achieve heat conduction. The peeling part 11a and the conductive part 11b will not be damaged by the laser 3. You can choose to use one of the peeling part 11a and the conductive part 11b or use the peeling part 11a and the conductive part 11b at the same time. The conductive part 11b can be selectively used. One or more of the magnetic substance and gold are mixed with each other, thereby preventing the generation of smoke (fume) and selectively or simultaneously performing the peeling effect and the heat transfer effect. The magnetic body can be made of metal material, etc., which will be described in the following content. In addition, when diamond, platinum and platinum are used, it is possible to ensure excellent heat conduction while ensuring that it will not melt due to the laser 3, and the horny 1 can be bounced and detached to the outside without being damaged. This ensures the safety of treatment. <Table 1 Laser treatment when the conductive part is gold>

Table 1 is an example. When the Q-switched Nd:TAG laser 3 with an energy density (fluence) of 1.6 J/㎠ and 5 ns is irradiated to the gold particles in the conductive part 11b, the gold particles will heat up to about 70°C, thus Maximizes the effects of whitening, melasma improvement, wrinkles, acne, pore reduction, and exfoliation. <Table 2 Thermal conductivity test of gold particles and carbon>

Table 2 shows the results of applying the laser 3 used in the treatment process to the gold particles of the conductive part 11b and applying the same laser 3 to the carbon particles. A significant difference in thermal conductivity of more than three times was observed. <Table 3 Absorption test of different particle sizes to ensure that the peeling part and conductive part in the enhancer composition are only absorbed by the epidermis> <Table 4 Test of forming a cluster of gold particles in the enhancer composition with the help of laser and thereby improving thermal conductivity>

At this time, the peeling part 11a and the conductive part 11b are formed with a particle size of 1 to 5㎛의 in order to maximize the peeling effect and appropriately adjust the absorption amount. The peeling part 11a and the conductive part 11b are formed with a particle size of 1 to 5㎛의 in order to maximize the peeling effect and appropriately adjust the absorption amount, thereby effectively absorbing the cutin 1 of the epidermal layer 2 of the person being treated. between. When the size of the particles exceeds 5㎛, the peeling effect will be significantly reduced. When the particle size is less than 1㎛, side effects may occur due to excessive absorption into the skin and it is easy to flow into the respiratory system. Said size can solve the problems mentioned above. When formed with a particle size of 1 to 5㎛, the appropriate particle size can be set according to the skin condition or skin location of the person being treated, and can be formed in various sizes.

That is, when carbon is used, it is formed and treated in a size of 55 to 40㎛ before treatment. However, after treatment, the carbon destroyed by the laser 3 floats in the air with a size of 1㎛ or less, so it is Carbon fumes destroyed to a size corresponding to ultrafine dust will be inhaled into the body in the form of respirable dust through the respiratory system, leading to a significant increase in the incidence of diseases such as cancer. In addition, the flue gas is a tiny solid particle generated by the solidification of vapor of solid matter or the chemical reaction of gaseous matter. It floats in the air and its size is less than 1㎛. Because its diameter is smaller than that of ordinary dust, it is difficult to settle. to the bottom surface, thereby being easily penetrated into the respiratory system. <Table 5 Before and after carbon treatment>

In addition, the magnetic material of the propagation part 11b uses one of the group consisting of Pt, Pd, Ag, Cu and Au or a mixture of one or more metal substances; from Co, Mn, Fe, Ni, Gd, Mo, A magnetic substance selected from the group consisting of MM'2O4 and MxOy (M and M' are each independently Co, Fe, Ni, Mn, Zn, Gd or Cr, 0 < x ≤3, 0 < y ≤5) or Magnetic alloy selected from the group consisting of CoCu, CoPt, FePt, CoSm, NiFe and NiFeCo. The magnetic substance is magnetic nanoparticles (nanoparticles) or magnetic nanoclusters clustered by the substance, and can exist in a dispersed form or a core form in the dielectric particles. The magnetic nanoparticles are preferably magnetic metal materials, magnetic materials or magnetic alloys. The magnetic substance may be a metal substance selected from the group consisting of Pt, Pd, Ag, Cu, and Au, or a mixture of more than one selected from the group consisting of Co, Mn, Fe, Ni, Gd, Mo, Select one or more from the group consisting of MM'2O4 and MxOy (M and M' are each independently Co, Fe, Ni, Mn, Zn, Gd or Cr, 0 < x ≤3, 0 < y ≤5) One or more magnetic alloys may be mixed from the group consisting of CoCu, CoPt, FePt, CoSm, NiFe, and NiFeCo.

In addition, the viscous part 12 of the present invention mixes the conductive part 11b with viscosity. The adhesive part 12 can mix the conductive part 11b formed with a certain size of powder or the like with each other through viscosity, and allows the conductive part 11b to be adhered to the patient's skin.

At this time, methylcellulose (CMC) is used for the adhesive portion 12 of the conductive portion 11b. The viscous part 12 can set the overall viscosity of the composition 10 using a water-soluble thickener, that is, methyl cellulose (CMC), and can also prevent the laser 3 from penetrating into the patient's skin, that is, the epidermis 2 . . In addition, the methylcellulose (CMC) of the sticky part 12 serves to mix all the ingredients with each other.

In addition, the ethanol 13 of the present invention can play a volatilization function. The ethanol 13 can be evaporated after a certain period of time after the composition 10 is applied to the patient's epidermal layer 2, so skin problems can be avoided without using ingredients such as oil, and it can flow into the patient's epidermal layer 2. The oil between them evaporates and is removed together.

In addition, the distilled water 14 of the present invention is used in a purified state. Distilled water 14 is used in a purified state. This is because when ordinary water is used, various substances such as calcium, magnesium, copper, and iron contained in ordinary water may cause a decrease in efficacy. Therefore, use purified clean water. Distilled water14.

At this time, the composition 10 is composed of 1 to 3 wt% of one or more mixtures of the peeling part 11a and the conductive part 11b, 1 to 3 wt% of the viscous part 12, 43 to 50 wt% of ethanol 13, and 45 to 45 wt% of the viscous part 12. Composed of 55wt% distilled water 14. The composition 10 is a mixture of one or more of the peeling part 11a and the conductive part 11b, ethanol 13 and distilled water 14, preferably composed of 1 wt% of one or more of the peeling part 11a and the conductive part 11b. Or more than one mixture, 1wt% viscous part 12, 48wt% ethanol 13 and 50wt% distilled water 14 is suitable. However, because different patients have different skin types, they can be mixed with each other in different proportions according to specific conditions. The composition 10 is produced and used, and the mixing ratio can be set according to the amount of cutin 1 in the epidermal layer 2, or the mixing ratio can be set according to the amount of cutin 1 to be removed.

As mentioned above, the present invention relates to a laser intensifier composition for improving chloasma, wrinkles, elasticity, pores and acne. In particular, it can reduce or prevent excessive damage caused by carbon intensifier laser treatment on the epidermis. Laser output causes the destruction of carbon and the generation of fine fume, thereby ensuring the health of the doctor who performs the treatment and the health of the patient receiving treatment, and can also prevent the generation of fine dust or fume, thereby reducing the environment pollution, and can prevent the occurrence of unpleasant odors such as burning smell due to laser, making the treatment more comfortable and enjoyable. It can also be used to improve chloasma, wrinkles, and elasticity through heat transfer in addition to peeling. The laser effect is maximized during laser treatment of pores, pores and wrinkles.

The present invention is not limited to the described embodiments, and those with general knowledge in the technical field will understand that various modifications and variations can be made to the present invention without departing from the spirit and scope thereof. Therefore, the modifications or variations should be construed as being included in the patentable scope of the present invention.

1: horny 2: Epidermal layer 3:Laser 10:Composition 11a: peeling part 11b:Conduction Department 12: Sticky part 13:Ethanol

1a to 1d are cross-sectional views illustrating in sequence the process of laser treatment using the laser enhancer composition for improving chloasma, wrinkles, elasticity, pores and acne of the present invention.

1: horny

2: Epidermal layer

10:Composition

11a: peeling part

11b:Conduction Department

12: Sticky part

13:Ethanol

Claims (6)

A laser enhancer composition for improving chloasma, wrinkles, elasticity, pores and acne, characterized by: As a composition for removing keratin (1) of the epidermal layer (2) by laser peeling treatment, A composition (10) that can be treated by being applied to the epidermal layer (2) is formed, and the composition (10) uses a peeling part (11a) that can achieve peeling and a conductive part (11b) that can achieve heat conduction. One or more mixtures to avoid being damaged by the laser (3) and generating fume, and through the viscous part that mixes the peeling part (11a) and the conductive part (11b) with the help of viscosity (12), volatilizable ethanol (13) and purified distilled water (14) are mixed with each other to form. The laser enhancer composition for improving chloasma, wrinkles, elasticity, pores and acne as described in claim 1, is characterized by: The peeling part (11a) of the composition (10) uses diamonds in a powder form of a certain size that can easily remove cuticles, and the conductive part (11b) uses diamonds in a powder form of a certain size that can achieve heat conduction. One or more mixtures of magnetic materials, gold and platinum. The laser enhancer composition for improving chloasma, wrinkles, elasticity, pores and acne as described in claim 2, is characterized by: The peeling part (11a) and the conductive part (11b) are formed with a particle size of 1 to 5㎛ in order to maximize the peeling effect and appropriately adjust the absorption amount. The laser enhancer composition for improving chloasma, wrinkles, elasticity, pores and acne as described in claim 2, is characterized by: The magnetic body of the mission (11b) uses one of the group consisting of Pt, Pd, Ag, Cu and Au or a mixture of more than one metal substance; from Co, Mn, Fe, Ni, Gd, Mo, A magnetic substance selected from the group consisting of MM'2O4 and MxOy (M and M' are each independently Co, Fe, Ni, Mn, Zn, Gd or Cr, 0 < x ≤3, 0 < y ≤5) or Magnetic alloy selected from the group consisting of CoCu, CoPt, FePt, CoSm, NiFe and NiFeCo. The laser enhancer composition for improving chloasma, wrinkles, elasticity, pores and acne as described in claim 1, is characterized by: Methyl cellulose (CMC) is used as the viscous part (12) of the conductive part (11b). The laser enhancer composition for improving chloasma, wrinkles, elasticity, pores and acne as described in claim 1, is characterized by: The composition (10) is composed of 45 to 55 wt% distilled water, 43 to 50 wt% ethanol, 1 to 3 wt% of one or more mixtures of the peeling part and the conductive part, and 1 to 3 wt% of the viscous part. .