TW202317586A - 治療性化合物及方法 - Google Patents

治療性化合物及方法 Download PDF

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Publication number
TW202317586A
TW202317586A TW111126584A TW111126584A TW202317586A TW 202317586 A TW202317586 A TW 202317586A TW 111126584 A TW111126584 A TW 111126584A TW 111126584 A TW111126584 A TW 111126584A TW 202317586 A TW202317586 A TW 202317586A
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Taiwan
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group
compound
groups
pharmaceutically acceptable
prodrug
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TW111126584A
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Chinese (zh)
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莎曼莎 艾利森 格林
潔西卡 瑪麗 格蘭德
史蒂芬 湯瑪斯 史戴本
內裡 阿瑪拉
維施瓦 Ｍ 狄克斯特
艾莉西亞 維勒木
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美商建南德克公司
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Publication of TW202317586A publication Critical patent/TW202317586A/zh

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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
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    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

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  • Diabetes (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW111126584A 2021-07-15 2022-07-15 治療性化合物及方法 TW202317586A (zh)

Applications Claiming Priority (2)

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US202163222288P 2021-07-15 2021-07-15
US63/222,288 2021-07-15

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TW202317586A true TW202317586A (zh) 2023-05-01

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US (2) US12006331B2 (enExample)
EP (1) EP4370130A4 (enExample)
JP (1) JP2024527604A (enExample)
KR (1) KR20240036571A (enExample)
CN (1) CN117642170A (enExample)
AR (1) AR126470A1 (enExample)
AU (1) AU2022309856A1 (enExample)
CA (1) CA3226225A1 (enExample)
CL (1) CL2024000114A1 (enExample)
CO (1) CO2024001017A2 (enExample)
CR (1) CR20240016A (enExample)
IL (1) IL309878A (enExample)
MX (1) MX2024000610A (enExample)
PE (1) PE20240776A1 (enExample)
TW (1) TW202317586A (enExample)
WO (1) WO2023287793A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3226225A1 (en) 2021-07-15 2023-01-19 Genentech, Inc. Therapeutic compounds and methods
WO2025082533A1 (zh) * 2023-10-21 2025-04-24 上海轶诺药业有限公司 一种稠环化合物及其制备和应用
EP4763280A1 (en) 2024-12-19 2026-06-24 Lead Discovery Center GmbH Pharmaceutically active pyrazolo[5,1-c][1,4]benzoxazepine derivatives

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Publication number Priority date Publication date Assignee Title
ATE267830T1 (de) * 1999-08-27 2004-06-15 Abbott Lab Als cox-hemmer verwendbare sulfonylphenylpyrazol- verbindungen
CN1391476A (zh) * 1999-09-27 2003-01-15 美国氰胺公司 血管升压素激动剂制剂和方法
AR039475A1 (es) 2002-05-01 2005-02-23 Wyeth Corp 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
US20070232582A1 (en) 2004-04-28 2007-10-04 Wyeth Holdings Corporation 4-substituted or unsubtituted-7-hydro-1,4-thiazepine-7-[bicyclic or tricyclic heteroaryl] substituted-3,6-dicarboxylic acid derivatives as beta-lactamase inhibitors
EP3813805A4 (en) * 2018-06-27 2021-08-25 Children's Medical Center Corporation INFLAMMATION INHIBITION COMPOUNDS
WO2020030613A1 (en) 2018-08-07 2020-02-13 Kemijski Institut Small molecule-inhibitors of 6-phosphofructo-1-kinase for reducing lactate generation by cancer cells
CA3226225A1 (en) 2021-07-15 2023-01-19 Genentech, Inc. Therapeutic compounds and methods

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CR20240016A (es) 2024-02-13
AR126470A1 (es) 2023-10-11
PE20240776A1 (es) 2024-04-17
EP4370130A4 (en) 2025-06-11
US12459957B2 (en) 2025-11-04
US20250109142A1 (en) 2025-04-03
CL2024000114A1 (es) 2024-08-02
CO2024001017A2 (es) 2024-03-07
US20230119740A1 (en) 2023-04-20
IL309878A (en) 2024-03-01
CA3226225A1 (en) 2023-01-19
JP2024527604A (ja) 2024-07-25
AU2022309856A1 (en) 2024-01-18
US12006331B2 (en) 2024-06-11
MX2024000610A (es) 2024-02-02
KR20240036571A (ko) 2024-03-20
WO2023287793A1 (en) 2023-01-19
EP4370130A1 (en) 2024-05-22
CN117642170A (zh) 2024-03-01

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