TW202115060A - 用於治療發炎病症之新穎化合物及其醫藥組合物 - Google Patents

用於治療發炎病症之新穎化合物及其醫藥組合物 Download PDF

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Publication number
TW202115060A
TW202115060A TW109128024A TW109128024A TW202115060A TW 202115060 A TW202115060 A TW 202115060A TW 109128024 A TW109128024 A TW 109128024A TW 109128024 A TW109128024 A TW 109128024A TW 202115060 A TW202115060 A TW 202115060A
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TW
Taiwan
Prior art keywords
int
amino
compound
pyrazolo
chloro
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TW109128024A
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English (en)
Chinese (zh)
Inventor
德 普拉斯 史蒂芬 艾蜜勒 凡
賽巴斯汀 勞倫 賽維亞 馬堤那
朱維尼 皮卓 都尼蘇 寇提
大衛 阿曼提尼
Original Assignee
比利時商葛萊伯格有限公司
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Application filed by 比利時商葛萊伯格有限公司 filed Critical 比利時商葛萊伯格有限公司
Publication of TW202115060A publication Critical patent/TW202115060A/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW109128024A 2019-08-19 2020-08-18 用於治療發炎病症之新穎化合物及其醫藥組合物 TW202115060A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1911868.6 2019-08-19
GBGB1911868.6A GB201911868D0 (en) 2019-08-19 2019-08-19 Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders

Publications (1)

Publication Number Publication Date
TW202115060A true TW202115060A (zh) 2021-04-16

Family

ID=68099572

Family Applications (1)

Application Number Title Priority Date Filing Date
TW109128024A TW202115060A (zh) 2019-08-19 2020-08-18 用於治療發炎病症之新穎化合物及其醫藥組合物

Country Status (5)

Country Link
EP (1) EP4017590A1 (fr)
AR (1) AR119792A1 (fr)
GB (1) GB201911868D0 (fr)
TW (1) TW202115060A (fr)
WO (1) WO2021032582A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115557947A (zh) * 2021-07-02 2023-01-03 成都百裕制药股份有限公司 吡唑并[4,3-c]吡啶衍生物及其在医药上的应用

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4091449A1 (fr) * 2021-05-19 2022-11-23 Syngenta Crop Protection AG Procédé de désherbage
TW202317561A (zh) * 2021-07-01 2023-05-01 美商羅曼德生物治療公司 作為治療劑的具有１ｈ—吡唑并［４，３—ｃ］吡啶—６—胺基的化合物
WO2023161327A1 (fr) * 2022-02-24 2023-08-31 Galapagos Nv Procédés de traitement de maladies inflammatoires et composé destiné à être utilisé dans ces procédés

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3235B1 (ar) * 2006-05-26 2018-03-08 Astex Therapeutics Ltd مركبات بيررولوبيريميدين و استعمالاتها
KR20130066703A (ko) * 2008-02-06 2013-06-20 노파르티스 아게 피롤로［２,３­ｄ］피리미딘 및 티로신 키나제 억제제로서 그의 용도
WO2013017480A1 (fr) * 2011-07-29 2013-02-07 Cellzome Limited Dérivés de pyrazolo[4,3-c]pyridine en tant qu'inhibiteurs de jak

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115557947A (zh) * 2021-07-02 2023-01-03 成都百裕制药股份有限公司 吡唑并[4,3-c]吡啶衍生物及其在医药上的应用
CN115557947B (zh) * 2021-07-02 2024-04-02 成都百裕制药股份有限公司 吡唑并[4,3-c]吡啶衍生物及其在医药上的应用

Also Published As

Publication number Publication date
AR119792A1 (es) 2022-01-12
EP4017590A1 (fr) 2022-06-29
GB201911868D0 (en) 2019-10-02
WO2021032582A1 (fr) 2021-02-25

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