TW202011832A - Compound nutrition and health-care product capable of rising body temperature to prevent disease which is manufactured by using main components including ginseng extract, licorice extract and jujube extract - Google Patents

Compound nutrition and health-care product capable of rising body temperature to prevent disease which is manufactured by using main components including ginseng extract, licorice extract and jujube extract Download PDF

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TW202011832A
TW202011832A TW107133487A TW107133487A TW202011832A TW 202011832 A TW202011832 A TW 202011832A TW 107133487 A TW107133487 A TW 107133487A TW 107133487 A TW107133487 A TW 107133487A TW 202011832 A TW202011832 A TW 202011832A
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body temperature
extract
ginsenoside
health
nutraceutical
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邢修賓
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邢雅婷
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The present invention discloses a compound nutrition and health-care product capable of rising body temperature to prevent disease, which is manufactured by using main components including ginseng extract, licorice extract and jujube extract. Moreover, the index components of the material of the nutrition and health-care product include: the ginseng extract having 2 to 27 weight parts of ginsenoside Rg1+Rg2; the licorice extract having 3 to 49 weight parts of glycyrrhizinate, which is selected from one of a glycyrrhizic acid, a glycyrrhetinic acid, and a combination thereof; and the jujube extract having 0.002 to 0.6 weight parts of jujube cyclic adenosine monophosphate.

Description

一種可使體溫上升以預防疾病的複方營養保健品 Compound nutrition and health care product capable of increasing body temperature to prevent disease

本發明係關於一種可使體溫上升以預防疾病的複方營養保健品,尤指一種包含以人參萃取物、甘草萃取物及大棗萃取物為原料製成的一種使體溫上升以預防疾病的複方營養保健品。 The present invention relates to a compound nutrition and health product that can increase body temperature to prevent disease, in particular to a compound nutrition made of ginseng extract, licorice extract and jujube extract as raw materials to increase body temperature to prevent disease Health products.

體溫是人類重要的生命徵象,現代醫學研究顯示,體溫和新陳代謝成正比,每當體溫增加1℃時,基礎代謝率增加大約13%,許多的研究顯示,體溫上升會大幅增強免疫力,人類及動物常採用升高體溫的方式對抗許多疾病,傳統的中醫亦認為,體寒是萬病之源。近年來,日本醫學博士石原結實醫師著作的許多本書中都指出,體溫上升可以大幅增加免疫力,而且可以防治許多疾病。2008年9月在紐約曼哈頓第五大道開設診所,與比爾蓋茲、柯林頓、貝克漢、A-Rod、小野洋子等名人深交的曼哈頓名醫齊藤真嗣醫師,也在他寫的書中指出,體溫降低1℃,免疫力會降低30%,低體溫還會使體內酸化,加速老化,而且會使健康的細胞新陳代謝惡化。因此,人類可以長期服用能增加體溫而且沒有不良副作用的保健品,來維持健康和預防及抵抗疾病。 Body temperature is an important vital sign of human beings. Modern medical research shows that body temperature is directly proportional to metabolism. When the body temperature increases by 1°C, the basal metabolic rate increases by about 13%. Many studies show that rising body temperature will greatly enhance immunity, human and Animals often use the method of raising body temperature to fight against many diseases. Traditional Chinese medicine also believes that body cold is the source of all diseases. In recent years, many books written by Ishihara Shikoshi, a doctor of medicine in Japan, have pointed out that a rise in body temperature can greatly increase immunity, and can prevent and cure many diseases. In September 2008, a clinic was opened on Fifth Avenue in Manhattan, New York. Dr. Saito Shinji, a famous doctor in Manhattan who had deep friendship with celebrities such as Bill Gates, Clinton, Beckham, A-Rod, Yoko Ono, also pointed out in his book. When the body temperature is lowered by 1°C, the immunity will be reduced by 30%. Low body temperature will also acidify the body, accelerate aging, and deteriorate the metabolism of healthy cells. Therefore, humans can take health products that increase body temperature without adverse side effects for a long time to maintain health and prevent and resist disease.

現有技術中,服用促進新陳代謝的甲狀腺激素(Thyroid Hormone),雖然可增加產熱使體溫上升,但是過量或劑量增加太快,可能會有心悸、脈壓升高、心律不整、心絞痛甚至心跳停止等不良副作用,而 服用治療支氣管疾病的茶鹼(Theophylline),也可增加產熱使體溫上升,但是可能會有頭痛、噁心、失眠、心悸等不良副作用。還有一些藥物會影響中樞系統對熱的調節生理機制使體溫上升,例如單胺氧化酶抑制劑(MAO-I)、Opioids類藥物,皆可能因增加熱的產生而影響體溫調節機制引起發燒,另外抗膽鹼激素藥物、三環類抗憂鬱藥物、抗組織胺劑及合成性生物鹼(如cocaine)亦會因影響下視丘體溫調節中樞及降低週邊排汗,而導致抗膽鹼激性的毒性症狀(anticholinergic toxidrome)出現發燒症狀。由於前述現有技術中可增加體溫的藥物,都有許多不良副作用的缺失,並不適合人類長期服用以增加體溫維持健康和預防疾病。因此,發明一種既可以增加體溫而且長期服用沒有不良副作用的保健品,讓人類可用以維持健康和預防及抵抗疾病,才能解決現有技術的缺失。 In the prior art, taking the thyroid hormone (Thyroid Hormone) that promotes metabolism, although it can increase the heat production and increase the body temperature, but excessive or excessive dose increase, there may be palpitations, increased pulse pressure, arrhythmia, angina pectoris and even heartbeat, etc. Adverse side effects, and taking theophylline for the treatment of bronchial diseases can also increase heat production and increase body temperature, but there may be adverse side effects such as headache, nausea, insomnia, and palpitations. There are also some drugs that affect the physiological mechanism of the central system's regulation of heat and increase body temperature. For example, monoamine oxidase inhibitors (MAO-I) and Opioids drugs may affect the body's temperature regulation mechanism due to increased heat generation and cause fever. Alkaline hormone drugs, tricyclic antidepressant drugs, antihistamines and synthetic alkaloids (such as cocaine) can also cause anticholinergic toxic symptoms due to the influence of the hypothalamic thermoregulatory center and lower peripheral sweating (anticholinergic toxidrome) fever symptoms. Because of the aforementioned drugs that can increase body temperature in the prior art, there are many undesirable side effects, which are not suitable for humans to take long-term to increase body temperature to maintain health and prevent diseases. Therefore, inventing a health product that can increase body temperature and take no adverse side effects for a long time, so that humans can maintain health and prevent and resist disease, can solve the lack of existing technology.

職是之故,吾人悉心研究與探索,並一本鍥而不捨之精神,以解決現有技術的缺失,終構思出本案之「一種可使體溫上升以預防疾病的複方營養保健品」,以下為本案之簡要說明。 Because of my job, I have studied and explored carefully, and worked hard to resolve the lack of existing technology, and finally conceived the "a compound nutritional health product that can increase body temperature to prevent disease" in this case. The following is the case. A brief description.

為了克服現有技術的不足,本發明的目的在於提供一種包含以人參萃取物、甘草萃取物及大棗萃取物為原料,製成的一種使體溫上升以預防疾病的複方營養保健品,特別是一種服用後不僅可以增加體溫而且長期服用沒有不良副作用的保健品,可讓人類長期服用以維持健康和預防及抵抗疾病的新技術方案。 In order to overcome the deficiencies of the prior art, the object of the present invention is to provide a compound nutritional health product made from ginseng extract, licorice extract and jujube extract as raw materials, which can increase body temperature to prevent disease, especially a After taking it, it can not only increase body temperature, but also take long-term health products without adverse side effects. It can be used by humans for a long time to maintain health and prevent and resist new diseases.

本發明一種使體溫上升以預防疾病的複方營養保健品的解決方案,是經吾人潛心研究探索並採用實施例進行實驗後證明之結果,由於先前技術中可增加體溫的藥物,都有許多不良副作用的缺失,並不適合人類為了增加體溫以維持健康預防治疾病而長期服用,因此,吾人 採用自古以來,人類日常食用的人蔘、甘草及大棗等植物中的成分為原料,製成一種既可以增加體溫而且長期服用也不會有不良副作用的複方營養保健品,可供人類長期服用以維持健康和預防及抵抗疾病。本發明複方營養保健品的原料包括:人參萃取物、甘草萃取物及大棗萃取物,而各萃取物的指標成分則包括人參皂甙Rg1及Rb1、甘草酸及甘草次酸、大棗環狀腺苷單磷酸。由於人蔘皂甙Re在人體內會代謝成為人蔘皂甙Rg1,所以製作本發明複方營養保健品時,當然也可以採用人蔘皂甙Re替代人蔘皂甙Rg1,且由於人蔘皂甙Rd在人體內會代謝成人蔘皂甙Rb1,所以製作本發明複方營養保健品時,當然也可以採用人蔘皂甙Rd替代人蔘皂甙Rb1。許多人服用本發明實施例之後,不僅體溫上升而且長期不感冒,也沒有不良副作用。足見應用本發明揭露的技術,可以製成適合人類長期服用使體溫上升以促進新陳代謝及增強免疫力的特醫食品、保健食品、營養輔助食品及藥品,而且具備長期服用安全性高的優點,更克服了現有技術有許多不良副作用的缺失及不足。 The present invention is a compound nutritional and health care product solution that raises body temperature to prevent disease, which is the result of our intensive research and exploration and experiments with examples. Since the drugs that can increase body temperature in the prior art have many adverse side effects The lack of is not suitable for humans to take for a long time in order to increase body temperature to maintain health and prevent diseases. Therefore, we have used ingredients from plants such as ginseng, licorice and jujube that humans have eaten daily since ancient times as raw materials to make a Compound nutrition and health products that increase body temperature and do not have adverse side effects for long-term use, can be used by humans for long-term use to maintain health and prevent and resist disease. The raw materials of the compound nutrition and health product of the present invention include: ginseng extract, licorice extract and jujube extract, and the index components of each extract include ginsenoside Rg1 and Rb1, glycyrrhizic acid and glycyrrhetinic acid, and jujube ring gland Glycoside monophosphate. Since ginsenoside Re is metabolized into ginsenoside Rg1 in the human body, of course, ginsenoside Re can also be used instead of ginsenoside Rg1 in the preparation of the compound nutritional and health care product of the present invention. It metabolizes the adult ginsenoside Rb1, so of course, when preparing the compound nutrition and health care product of the present invention, human ginsenoside Rd can also be used instead of human ginsenoside Rb1. After taking the embodiments of the present invention, many people not only have a rise in body temperature but also do not have a cold for a long time, and have no adverse side effects. It can be seen that the technology disclosed in the present invention can be made into special medical foods, health foods, nutritional supplementary foods and medicines suitable for long-term use by humans to increase body temperature to promote metabolism and enhance immunity, and has the advantages of high safety for long-term use. It overcomes the shortcomings and deficiencies of the prior art with many adverse side effects.

本發明係揭露一種可使體溫上升以預防疾病的複方營養保健品,該營養保健品的原料包括:人參萃取物、甘草萃取物及大棗萃取物。 The invention discloses a compound nutritional health product which can increase body temperature to prevent diseases. The raw materials of the nutritional health product include: ginseng extract, licorice extract and jujube extract.

較佳者,本發明之營養保健品的原料的指標成分包括:該人參萃取物包含2~27重量份的人參皂甙(Rg1+Rb1);及該甘草萃取物包含3~49重量份的甘草酸類,且該甘草酸類係選自一甘草酸、一甘草次酸及其組合之一;及該大棗萃取物包含0.002~0.6重量份的大棗環狀腺苷單磷酸。 Preferably, the index components of the raw materials of the nutraceuticals of the present invention include: the ginseng extract contains 2 to 27 parts by weight of ginsenoside (Rg1+Rb1); and the licorice extract contains 3 to 49 parts by weight of glycyrrhizic acid , And the glycyrrhizic acid is selected from one of glycyrrhizic acid, glycyrrhetinic acid and combinations thereof; and the jujube extract contains 0.002~0.6 parts by weight of jujube cyclic adenosine monophosphate.

較佳者,本發明之營養保健品包括含有選自食品營養學及藥學上可接受的一載體、一添加劑及其組合之一。 Preferably, the nutraceutical of the present invention includes one selected from food nutrition and pharmaceutically acceptable carrier, additive and combinations thereof.

較佳者,本發明之營養保健品包括製成一劑型,該劑型係選自一錠劑、一膠囊劑、一散劑、一片劑、一粉劑、一溶液劑、一微囊劑、一混懸劑、一乳劑、一顆粒劑、一滴丸劑、一丸劑及藥劑學上的一口服劑型其中之一。 Preferably, the nutraceutical of the present invention includes a dosage form selected from a lozenge, a capsule, a powder, a tablet, a powder, a solution, a microcapsule, and a suspension One of an agent, an emulsion, a granule, a pill, a pill, and an oral dosage form in pharmacy.

較佳者,本發明之營養保健品包括可以製成使體溫上升以促進新陳代謝及增強免疫力的特醫食品、保健食品、營養輔助食品及藥品。 Preferably, the nutraceuticals of the present invention include special medical foods, health foods, nutritional supplement foods, and medicines that can be made to increase body temperature to promote metabolism and enhance immunity.

根據本發明之另一概念,本發明係揭露一種可使體溫上升以預防疾病的複方營養保健品,該營養保健品包括:一第一主要成份,包含2~27重量份的人參皂甙(Rg1+Rb1);及一第二主要成份,包含3~49重量份的甘草酸類,且該甘草酸類係選自一甘草酸、一甘草次酸及其組合之一;及一第三主要成份,包含0.002~0.6重量份的大棗環狀腺苷單磷酸。 According to another concept of the present invention, the present invention discloses a compound nutritional health care product that can increase body temperature to prevent disease. The nutritional health care product includes: a first main component, including 2 to 27 parts by weight of ginsenoside (Rg1+ Rb1); and a second main ingredient, including 3 to 49 parts by weight of glycyrrhizic acid, and the glycyrrhizic acid is selected from one of glycyrrhizic acid, a glycyrrhetinic acid, and a combination thereof; and a third main ingredient, including 0.002 ~0.6 parts by weight of jujube cyclic adenosine monophosphate.

較佳者,本發明之營養保健品包括含有選自食品營養學及藥學上可接受的一載體、一添加劑及其組合之一。 Preferably, the nutraceutical of the present invention includes one selected from food nutrition and pharmaceutically acceptable carrier, additive and combinations thereof.

較佳者,本發明之營養保健品包括製成一劑型,該劑型係選自一錠劑、一膠囊劑、一散劑、一片劑、一粉劑、一溶液劑、一微囊劑、一混懸劑、一乳劑、一顆粒劑、一滴丸劑、一丸劑及藥劑學上的一口服劑型其中之一。 Preferably, the nutraceutical of the present invention includes a dosage form selected from a lozenge, a capsule, a powder, a tablet, a powder, a solution, a microcapsule, and a suspension One of an agent, an emulsion, a granule, a pill, a pill, and an oral dosage form in pharmacy.

較佳者,本發明之營養保健品包括可以製成使體溫上升以促進新陳代謝及增強免疫力的特醫食品、保健食品、營養輔助食品及藥品。 Preferably, the nutraceuticals of the present invention include special medical foods, health foods, nutritional supplement foods, and medicines that can be made to increase body temperature to promote metabolism and enhance immunity.

根據本發明之另一概念,一種可使體溫上升以預防疾病的複方營養保健品,該營養保健品包括:一第一主要成份,包含一第一人參皂甙類(係選自一人參皂甙Rg1、一人參皂甙Re及其組合之一),以及一 第二人參皂甙類(係選自一人參皂甙Rb1、一人參皂甙Rd及其組合之一);及一第二主要成份,包含一甘草酸類(係選自一甘草酸、一甘草次酸及其組合之一);及一第三主要成份,包含一大棗環狀腺苷單磷酸製成。 According to another concept of the present invention, a compound nutritional health product that can increase body temperature to prevent disease, the nutritional health product includes: a first main ingredient, including a first ginsenoside (selected from a ginsenoside Rg1 One ginsenoside Re and one of its combinations), and one second ginsenoside (selected from one of ginsenoside Rb1, one ginsenoside Rd and combinations thereof); and a second main component, including one glycyrrhizic acid ( It is selected from one of glycyrrhizic acid, glycyrrhetinic acid and their combinations); and a third main component, which is made of a large jujube cyclic adenosine monophosphate.

本發明說明書和申請專利範圍中所述之一種可使體溫上升以預防疾病的複方營養保健品,是實現本發明目的的核心內容,在本發明公開後,本領域的技術人員對上述營養保健品進行常規的加減化裁,均屬於本領域技術和研究人員的一般性技術活動,故其都在本發明的保護範圍之內。 A compound nutritional health product that can increase body temperature to prevent disease as described in the description and patent application scope of the present invention is the core content of achieving the purpose of the present invention. After the disclosure of the present invention, those skilled in the art Performing conventional addition and subtraction is a general technical activity of those skilled in the art and researchers, so they are all within the protection scope of the present invention.

本發明得藉參閱如附圖示及詳細說明而獲較佳瞭解。 The invention can be better understood by referring to the drawings and detailed description.

以下將結合附圖和實施例進一步說明本發明。本發明主要是採用本領域技術人員習知的方法結合本發明的特徵製備本發明所述的複方營養保健品。以下實施例僅僅是為了說明,並非限定本發明。 The present invention will be further described below with reference to the drawings and embodiments. The present invention is mainly to prepare the compound nutrition and health product of the present invention by combining the characteristics of the present invention with a method known to those skilled in the art. The following examples are for illustration only and do not limit the invention.

為了完成本發明的目的,本發明特別提出下列技術方案。 In order to accomplish the object of the present invention, the present invention particularly proposes the following technical solutions.

本發明係揭露一種可使體溫上升以預防疾病的複方營養保健品,它是由包括人參萃取物、甘草萃取物及大棗萃取物等原料所製成。 The present invention discloses a compound nutrition and health product that can increase body temperature to prevent diseases. It is made of raw materials including ginseng extract, licorice extract and jujube extract.

方案一: Option One:

以含有人參萃取物、甘草萃取物及大棗萃取物的原料,加工製成本發明一種可使體溫上升以預防疾病的複方營養保健品。 The raw material containing ginseng extract, licorice extract and jujube extract is processed into a compound nutrition and health product of the present invention which can increase body temperature to prevent disease.

方案二: Option II:

以含有2~27重量份的人參皂甙(Rg1+Rb1)的人參萃取物、含有3~49重量份的甘草酸類(且該甘草酸類係選自一甘草酸、一甘草次酸及其組 合之一)的甘草萃取物、含有0.002~0.6重量份的大棗環狀腺苷單磷酸的大棗萃取物的原料,加工製成本發明的複方營養保健品。 A ginseng extract containing 2 to 27 parts by weight of ginsenoside (Rg1+Rb1), containing 3 to 49 parts by weight of glycyrrhizic acid (and the glycyrrhizic acid is selected from one of glycyrrhizic acid, one glycyrrhetinic acid and one of their combinations ) The licorice extract and the raw material of the jujube extract containing 0.002~0.6 parts by weight of jujube cyclic adenosine monophosphate are processed into the compound nutrition and health product of the present invention.

方案三: third solution:

本發明之複方營養保健品包括可以含有食品營養學及藥學上可接受的載體或添加劑,可以製成錠劑、膠囊劑、散劑等任何藥劑學上所公知的口服藥物劑型。 The compound nutraceuticals of the present invention include food nutrition and pharmaceutically acceptable carriers or additives, and can be made into tablets, capsules, powders, and any other well-known oral pharmaceutical dosage forms.

方案四: Option four:

本發明之營養保健品包括可以製成使體溫上升以促進新陳代謝及增強免疫力的特醫食品、保健食品、營養輔助食品及藥品。 The nutrition and health products of the present invention include special medical foods, health foods, nutritional supplement foods and medicines that can be made to increase body temperature to promote metabolism and enhance immunity.

方案五: Option five:

以含有2~27重量份的人參皂甙(Rg1+Rb1)的一第一主要成份、含有3~49重量份的甘草酸類(且該甘草酸類係選自一甘草酸、一甘草次酸及其組合之一)的一第二主要成份、含有0.002~0.6重量份的大棗環狀腺苷單磷酸的一第三主要成份的原料,加工製成本發明一種可使體溫上升以預防疾病的複方營養保健品。 A first main component containing 2 to 27 parts by weight of ginsenoside (Rg1+Rb1), containing 3 to 49 parts by weight of glycyrrhizic acid (and the glycyrrhizic acid is selected from monoglycyrrhizic acid, monoglycyrrhetinic acid and combinations thereof (1) A second main component, a raw material containing 0.002~0.6 parts by weight of a third main component of jujube cyclic adenosine monophosphate, processed into a compound nutritional health care of the present invention that can increase body temperature to prevent disease Goods.

方案六: Option 6:

以含有一第一人參皂甙類(係選自一人參皂甙Rg1、一人參皂甙Re及其組合之一)及一第二人參皂甙類(係選自一人參皂甙Rb1、一人參皂甙Rd及其組合之一)的一第一主要成份、含有一甘草酸類(係選自一甘草酸、一甘草次酸及其組合之一)的一第二主要成份、含有一大棗環狀腺苷單磷酸的一第三主要成份的原料,加工製成本發明一種可使體溫上升以預防疾病的複方營養保健品。 Contains a first ginsenoside (selected from a ginsenoside Rg1, a ginsenoside Re and one of its combinations) and a second ginsenoside (selected from a ginsenoside Rb1, a ginsenoside Rd and a combination thereof One) a first main component, containing a glycyrrhizic acid (selected from one of glycyrrhizic acid, one of glycyrrhetinic acid and combinations thereof), a second main component containing a large date cyclic adenosine monophosphate A raw material of the third main component is processed into a compound nutritional health product of the present invention which can increase body temperature to prevent disease.

為了完成本發明的目的,特提出以下複方營養保健品的製作方法。 In order to accomplish the purpose of the present invention, the following method for making compound nutrition and health products is specifically proposed.

方法一: method one:

將含有人參萃取物、甘草萃取物及大棗萃取物的原料,加工製成本發明一種可使體溫上升以預防疾病的複方營養保健品。 The raw materials containing ginseng extract, licorice extract and jujube extract are processed into a compound nutrition and health product of the present invention which can increase body temperature to prevent disease.

方法二: Method Two:

將含有2~27重量份的人參皂甙(Rg1+Rb1)的人參萃取物、含有3~49重量份的甘草酸類(且該甘草酸類係選自一甘草酸、一甘草次酸及其組合之一)的甘草萃取物、含有0.002~0.6重量份的大棗環狀腺苷單磷酸的大棗萃取物的原料,加工製成本發明的複方營養保健品。 The ginseng extract containing 2 to 27 parts by weight of ginsenoside (Rg1+Rb1) and 3 to 49 parts by weight of glycyrrhizic acid (and the glycyrrhizic acid is selected from one of glycyrrhizic acid, one glycyrrhetinic acid and one of their combinations ) The licorice extract and the raw material of the jujube extract containing 0.002~0.6 parts by weight of jujube cyclic adenosine monophosphate are processed into the compound nutrition and health product of the present invention.

方法三: Method three:

將本發明之複方營養保健品加上含有食品營養學及藥學上可接受的載體或添加劑,製成錠劑、膠囊劑、散劑等任何藥劑學上所公知的口服藥物劑型。 The compound nutritional and health-care product of the present invention plus food nutrition and pharmacologically acceptable carriers or additives are made into tablets, capsules, powders, and any other known pharmaceutical dosage forms for oral administration.

方法四: Method 4:

將本發明之營養保健品製成使體溫上升以促進新陳代謝及增強免疫力的特醫食品、保健食品、營養輔助食品及藥品。 The nutraceuticals of the present invention are made into special medical foods, health foods, nutritional supplement foods and medicines that increase body temperature to promote metabolism and enhance immunity.

方法五: Method 5:

將含有2~27重量份的人參皂甙(Rg1+Rb1)的一第一主要成份、含有3~49重量份的甘草酸類(且該甘草酸類係選自一甘草酸、一甘草次酸及其組合之一)的一第二主要成份、含有0.002~0.6重量份的大棗環狀腺苷單磷酸的一第三主要成份的原料,加工製成本發明一種可使體溫上升以預防疾病的複方營養保健品。 A first main component containing 2 to 27 parts by weight of ginsenoside (Rg1+Rb1) and 3 to 49 parts by weight of glycyrrhizic acid (and the glycyrrhizic acid is selected from monoglycyrrhizic acid, monoglycyrrhetinic acid and combinations thereof (1) A second main component, a raw material containing 0.002~0.6 parts by weight of a third main component of jujube cyclic adenosine monophosphate, processed into a compound nutritional health care of the present invention that can increase body temperature to prevent disease Goods.

方法六: Method 6:

將含有一第一人參皂甙類(係選自一人參皂甙Rg1、一人參皂甙Re及其組合之一)及一第二人參皂甙類(係選自一人參皂甙Rb1、一人參皂甙Rd及其組合之一)的一第一主要成份、含有一甘草酸類(係選自一甘草酸、一甘草次酸及其組合之一)的一第二主要成份、含有一大棗環狀腺苷單 磷酸的一第三主要成份的原料,加工製成本發明一種可使體溫上升以預防疾病的複方營養保健品。 Will contain a first ginsenoside (selected from one ginsenoside Rg1, one ginsenoside Re and one of its combinations) and a second ginsenoside (selected from one ginsenoside Rb1, one ginsenoside Rd and its combination One) a first main component, containing a glycyrrhizic acid (selected from one of glycyrrhizic acid, one of glycyrrhetinic acid and combinations thereof), a second main component containing a large date cyclic adenosine monophosphate A raw material of the third main component is processed into a compound nutritional health product of the present invention which can increase body temperature to prevent disease.

【具體實施例】 [Specific embodiment]

以下將結合附圖和具體實施案例進一步說明本發明。 The present invention will be further described below with reference to the drawings and specific implementation cases.

實施例一 Example one

請參閱第一圖,為製備本發明實施例一複方營養保健品的方法流程示意圖。在第一圖中,將30kg的人參破碎後用70%乙醇溶液加溫萃取,經上柱層析分離純化、乾燥,得含143g人參皂甙Rg1+Rb1之人參萃取物1.1kg;並將10kg的甘草破碎後用70%乙醇溶液加溫萃取,濃縮乾燥後,得含甘草酸196g的甘草萃取物1.9kg;且將20kg的大棗破碎後加水常溫浸泡,再過濾浸泡液後獲得大棗萃取液,再用大孔樹脂上柱吸附分離純化、乾燥,得含大棗cAMP 1.113g的大棗萃取物66.3g作為原料供製備本發明複方營養保健品;之後,將上述方法得到的人參萃取物100g、甘草萃取物200g及大棗萃取物9.2g粉碎混合均勻後,得309.2g本發明方案一的複方營養保健品。 Please refer to the first figure, which is a schematic flowchart of a method for preparing a compound nutrition and health product according to an embodiment of the present invention. In the first picture, 30kg of ginseng is crushed and then extracted with 70% ethanol solution, then purified by upper column chromatography and dried to obtain 1.1kg of ginseng extract containing 143g of ginsenoside Rg1+Rb1; and 10kg of After the licorice is crushed, it is heated and extracted with a 70% ethanol solution. After concentration and drying, a licorice extract containing 196g of glycyrrhizic acid is obtained 1.9kg; and 20kg of the jujube is crushed and then immersed in water at room temperature, and then the soaking solution is filtered to obtain the jujube extract Then, the macroporous resin was used for adsorption separation and purification, and dried to obtain the jujube extract containing 6113g of jujube cAMP 1.113g as raw material for preparing the compound nutrition and health product of the present invention; after that, the ginseng extract obtained by the above method was 100g After 200g of licorice extract and 9.2g of jujube extract are crushed and mixed uniformly, 309.2g of the compound nutrition and health product of the first scheme of the present invention is obtained.

實施例二 Example 2

請參閱第二圖,為製備本發明實施例二複方營養保健品的方法流程示意圖。在第二圖中,將實施例一得到的人參萃取物120g及大棗萃取物2g加上市售的24g純度為96%的甘草次酸粉碎混合均勻後,得146g本發明方案五的複方營養保健品。 Please refer to the second figure, which is a schematic flowchart of a method for preparing a compound nutritional and health care product according to Embodiment 2 of the present invention. In the second figure, after 120g of ginseng extract obtained in Example 1 and 2g of jujube extract are added to the market, 24g of 96% glycyrrhetinic acid with a purity of 96% is crushed and mixed to obtain 146g of the compound nutrition of the fifth embodiment of the present invention Goods.

實驗例一:實施例一使體溫上升試驗 Experimental example one: Example one experiment of increasing body temperature

1.試驗人數: 1. Number of testers:

16名成年人,性別及年齡分佈情形如表1。 The distribution of 16 adults by gender and age is shown in Table 1.

Figure 107133487-A0101-12-0009-1
Figure 107133487-A0101-12-0009-1

2.試驗方式: 2. Test method:

將實施例一製作成營養輔助食品膠囊提供給試驗者服用,試驗者服用實施例一之前先測量個人平均體溫,每天服用800毫克的實施例一連續7天後,再測量個人平均體溫。 The nutritional supplement food capsule made in Example 1 is provided to the tester for taking. The tester measures the average body temperature of the individual before taking Example 1. After taking 800 mg of Example 1 every day for 7 consecutive days, the average personal temperature is measured.

3.試驗結果: 3. Test results:

試驗者中有13人平均體溫上升0.4℃以上,無不良副作用。 Thirteen of the testers had an average body temperature rise of more than 0.4°C without adverse side effects.

實驗例二:實施例一預防感冒試驗 Experimental example 2: Example 1 cold prevention test

1.試驗人數: 1. Number of testers:

6名成年人,性別及年齡分佈情形如表2。 The distribution of sex and age of 6 adults is shown in Table 2.

Figure 107133487-A0101-12-0009-2
Figure 107133487-A0101-12-0009-2

2.試驗方式: 2. Test method:

將實施例一製作成營養輔助食品膠囊提供給試驗者服用,試驗者每天服用800毫克的實施例一連續6個月。 The nutritional supplementary food capsules of Example 1 were prepared and provided to the tester. The tester took 800 mg of Example 1 every day for 6 consecutive months.

3.試驗結果: 3. Test results:

試驗過程中,5人無感冒現象,1人有喉嚨不適現象兩天,無不良副作用。 During the test, 5 people did not have a cold, and 1 person had a sore throat for 2 days without adverse side effects.

本發明一種可使體溫上升以預防疾病的複方營養保健品的應用範圍: 1.本發明所述的一種可使體溫上升以預防疾病的複方營養保健品中,可以含有食品營養學及藥物學上可接受的添加劑; 2.本發明所述的一種可使體溫上升以預防疾病的複方營養保健品可以將其加工製成散劑、膠囊劑、片劑、等各種習知的劑型;以及 3.本發明所述的一種可使體溫上升以預防疾病的複方營養保健品可以製成使體溫上升以促進新陳代謝及增強免疫力的特醫食品、保健食品、營養輔助食品及藥品。 The application range of the compound nutrition and health product of the present invention that can increase body temperature to prevent diseases: 1. The compound nutrition and health product of the present invention that can increase body temperature to prevent diseases can contain food nutrition and pharmacology. Acceptable additives; 2. A compound nutritional health product according to the present invention that can increase body temperature to prevent disease can be processed into powders, capsules, tablets, and other conventional dosage forms; and 3. According to the invention, a compound nutritional health product that can increase body temperature to prevent disease can be made into special medical food, health food, nutritional supplement food and medicine that increase body temperature to promote metabolism and enhance immunity.

本案得由熟悉此技藝之人任施匠思而為諸般修飾,然皆不脫如附申請範圍所欲保護者。 This case may be modified by anyone familiar with this skill, such as Shi Jiangsi, but none of them are as protected as the scope of the application.

第一圖為製備本發明實施例一營養保健品的方法流程示意圖。 The first figure is a schematic flow chart of a method for preparing a nutrition and health product according to Embodiment 1 of the present invention.

第二圖為製備本發明方案五營養保健品的方法流程示意圖。 The second figure is a schematic flow chart of the method for preparing the nutrition and health care product of the fifth scheme of the present invention.

Claims (10)

一種可使體溫上升以預防疾病的複方營養保健品,該營養保健品的原料包括:人參萃取物、甘草萃取物及大棗萃取物。 A compound nutritional and health-care product capable of raising body temperature to prevent disease. The raw materials of the nutritional and health-care product include: ginseng extract, licorice extract and jujube extract. 如申請專利範圍第1項所述的營養保健品,其中該營養保健品的原料的指標成分包括:該人參萃取物包含2~27重量份的人參皂甙Rg1+Rb1;及該甘草萃取物包含3~49重量份的甘草酸類,且該甘草酸類係選自一甘草酸、一甘草次酸及其組合之一;及該大棗萃取物包含0.002~0.6重量份的大棗環狀腺苷單磷酸。 The nutraceutical product according to item 1 of the patent application scope, wherein the index components of the raw material of the nutraceutical product include: the ginseng extract contains 2 to 27 parts by weight of ginsenoside Rg1+Rb1; and the licorice extract contains 3 ~49 parts by weight of glycyrrhizic acid, and the glycyrrhizic acid is selected from one of glycyrrhizic acid, glycyrrhetinic acid and combinations thereof; and the jujube extract contains 0.002~0.6 parts by weight of cyclic adenosine monophosphate . 如申請專利範圍第1項所述的營養保健品,其中該營養保健品包括含有選自食品營養學及藥學上可接受的一載體、一添加劑及其組合之一。 The nutraceutical as recited in item 1 of the patent application scope, wherein the nutraceutical includes a carrier selected from food nutrition and pharmaceutically acceptable, an additive, and a combination thereof. 如申請專利範圍第1項所述的營養保健品,其中該營養保健品包括製成一劑型,該劑型係選自一錠劑、一膠囊劑、一散劑、一片劑、一粉劑、一溶液劑、一微囊劑、一混懸劑、一乳劑、一顆粒劑、一滴丸劑、一丸劑及藥劑學上的一口服劑型其中之一。 The nutraceutical product as described in item 1 of the patent application scope, wherein the nutraceutical product comprises a dosage form selected from a lozenge, a capsule, a powder, a tablet, a powder, a solution , One microcapsule, one suspension, one emulsion, one granule, one pill, one pill, and one of pharmacological oral dosage forms. 如申請專利範圍第1項所述的營養保健品,其中該營養保健品包括可以製成使體溫上升以促進新陳代謝及增強免疫力的特醫食品、保健食品、營養輔助食品及藥品。 The nutraceuticals as described in item 1 of the patent application scope, wherein the nutraceuticals include special medical foods, health foods, nutritional supplement foods and medicines that can be made to increase body temperature to promote metabolism and enhance immunity. 一種可使體溫上升以預防疾病的複方營養保健品,該營養保健品包括:一第一主要成份:包含2~27重量份的人參皂甙Rg1+Rb1;及一第二主要成份:包含3~49重量份的甘草酸類,且該甘草酸類係選自一甘草酸、一甘草次酸及其組合之一;及一第三主要成份:包含0.002~0.6重量份的大棗環狀腺苷單磷酸。 A compound nutritional health product that can increase body temperature to prevent disease, the nutritional health product includes: a first main component: containing 2~27 parts by weight of ginsenoside Rg1+Rb1; and a second main component: containing 3~49 Glycyrrhizic acid by weight, and the glycyrrhizic acid is selected from one of glycyrrhizic acid, glycyrrhetinic acid and combinations thereof; and a third main component: containing 0.002~0.6 parts by weight of cyclic adenosine monophosphate. 如申請專利範圍第1項所述的營養保健品,其中該營養保健品包括含有選自食品營養學及藥學上可接受的一載體、一添加劑及其組合之一。 The nutraceutical as recited in item 1 of the patent application scope, wherein the nutraceutical includes a carrier selected from food nutrition and pharmaceutically acceptable, an additive, and a combination thereof. 如申請專利範圍第1項所述的營養保健品,其中該營養保健品包括製成一劑型,該劑型係選自一錠劑、一膠囊劑、一散劑、一片劑、一粉劑、一溶液劑、一微囊劑、一混懸劑、一乳劑、一顆粒劑、一滴丸劑、一丸劑及藥劑學上的一口服劑型其中之一。 The nutraceutical product as described in item 1 of the patent application scope, wherein the nutraceutical product comprises a dosage form selected from a lozenge, a capsule, a powder, a tablet, a powder, a solution , One microcapsule, one suspension, one emulsion, one granule, one pill, one pill, and one of pharmacological oral dosage forms. 如申請專利範圍第1項所述的營養保健品,其中該營養保健品包括可以製成使體溫上升以促進新陳代謝及增強免疫力的特醫食品、保健食品、營養輔助食品及藥品。 The nutraceuticals as described in item 1 of the patent application scope, wherein the nutraceuticals include special medical foods, health foods, nutritional supplement foods and medicines that can be made to increase body temperature to promote metabolism and enhance immunity. 一種可使體溫上升以預防疾病的複方營養保健品,該營養保健品包括:一第一主要成份:包含一第一人參皂甙類,係選自一人參皂甙Rg1、一人參皂甙Re及其組合之一,以及一第二人參皂甙類,係選自一人參皂甙Rb1、一人參皂甙Rd及其組合之一;及一第二主要成份:包含一甘草酸類,係選自一甘草酸、一甘草次酸及其組合之一;及一第三主要成份:包含一大棗環狀腺苷單磷酸製成。 A compound nutraceutical that can increase body temperature to prevent disease. The nutraceutical includes: a first main ingredient: a first ginsenoside, selected from a ginsenoside Rg1, a ginsenoside Re, and combinations thereof One, and a second ginsenoside, selected from one of ginsenoside Rb1, one ginsenoside Rd, and combinations thereof; and a second main ingredient: containing one glycyrrhizic acid, selected from one glycyrrhizic acid, one glycyrrhizin Acid and one of its combinations; and a third main ingredient: made from a large jujube cyclic adenosine monophosphate.
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