TW201940512A - 具有與ＦｃＲｎ增進的結合及延長的半衰期之Ｆｃ變異體 - Google Patents
具有與ＦｃＲｎ增進的結合及延長的半衰期之Ｆｃ變異體 Download PDFInfo
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- C07K—PEPTIDES
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Landscapes
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| WO2011089211A1 (en) * | 2010-01-22 | 2011-07-28 | Synimmune Gmbh | Anti-cd133 antibodies and methods of using the same |
| TWI671315B (zh) | 2011-03-28 | 2019-09-11 | 法商賽諾菲公司 | 具有交叉結合區定向之雙重可變區類抗體結合蛋白 |
| GB201112429D0 (en) * | 2011-07-19 | 2011-08-31 | Glaxo Group Ltd | Antigen-binding proteins with increased FcRn binding |
| WO2013047748A1 (ja) | 2011-09-30 | 2013-04-04 | 中外製薬株式会社 | 複数の生理活性を有する抗原の消失を促進する抗原結合分子 |
| US20140294812A1 (en) * | 2013-03-15 | 2014-10-02 | Xencor, Inc. | Fc variants that improve fcrn binding and/or increase antibody half-life |
| CN105164157B (zh) * | 2013-04-29 | 2024-05-28 | 豪夫迈·罗氏有限公司 | Fc-受体结合的修饰的非对称抗体及使用方法 |
| HUE045466T2 (hu) * | 2014-11-06 | 2019-12-30 | Hoffmann La Roche | Fc-régió-variánsok módosított FcRn-kötéssel és alkalmazási eljárások |
| CN107074942A (zh) | 2014-11-10 | 2017-08-18 | 豪夫迈·罗氏有限公司 | 抗‑IL‑1β抗体和使用方法 |
| JP7464389B2 (ja) * | 2016-08-02 | 2024-04-09 | ビステラ， インコーポレイテッド | 操作されたポリペプチドおよびその使用 |
| IL318916A (en) * | 2018-01-26 | 2025-04-01 | Genzyme Corp | FC variants with improved binding to FCRN and extended half-life |
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2019
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| CN119350481A (zh) | 2025-01-24 |
| JP2024026255A (ja) | 2024-02-28 |
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| MY203898A (en) | 2024-07-23 |
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| EP3743441A1 (en) | 2020-12-02 |
| IL276286B2 (en) | 2025-07-01 |
| WO2019147973A1 (en) | 2019-08-01 |
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| CN111788221A (zh) | 2020-10-16 |
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| CA3089602A1 (en) | 2019-08-01 |
| AU2019212638B2 (en) | 2025-04-03 |
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| US20190263934A1 (en) | 2019-08-29 |
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| MX2020007882A (es) | 2020-12-03 |
| AU2025204826A1 (en) | 2025-07-17 |
| JP7399880B2 (ja) | 2023-12-18 |
| RU2020128177A (ru) | 2022-02-28 |
| NZ767453A (en) | 2025-03-28 |
| KR102748986B1 (ko) | 2025-01-02 |
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