TW201900106A - Portable Device of Monitoring Hemodialysis Access Status - Google Patents

Abstract

A portable device of monitoring hemodialysis access status is disclosed. The portable device comprises a measuring device and a monitoring module. The measuring device senses a vibration data induced by blood flow over certain part of a hemodialysis access of a subject via a vibration-sensing module, and sends the sensed data to outside via its communication module. The monitoring module controls an electronic device to receive the sensed data and determines an evaluation index corresponding to a status of the part of the hemodialysis access.

Description

Portable vascular access condition monitoring device

The present invention relates to vascular access condition monitoring, and more particularly to portable vascular access condition monitoring devices.

Patients with loss or incomplete renal function must rely on vascular access to send blood to a hemodialysis machine outside the body for blood purification to filter out waste in the blood. The aforementioned vascular access can be manufactured surgically and used to deliver the patient's blood to the hemodialysis machine and deliver the dialyzed blood back to the patient.

In general, there are two main types of vascular accesses made by surgery: Arteriovenous Fistula (AVF) and Arteriovenous Graft (AVG).

Please refer to FIG. 1A , which is a schematic diagram of an arteriovenous artificial blood vessel. The arteriovenous artificial blood vessel 14 may be an artificial plastic tube having one end connected to the artery 12 and one end connected to the vein 10. Please refer to FIG. 1B , which is a schematic diagram of an arteriovenous fistula. The arteriovenous fistula 16 directly connects the artery 12 and the vein 10.

Any of the above vascular accesses may have a narrow or even clogging of the tube. Once the vascular access is blocked or narrowed, the hemodialysis effect may be poor, and even in severe cases, the life of the patient may be endangered. Therefore, vascular access status monitoring has become an important issue.

In the existing monitoring of vascular access status, a large-volume, high-cost ultrasonic image capturing device is used to capture the ultrasonic image of the vascular access and calculate the blood flow, and the professional medical staff diagnoses the blood vessel based on the ultrasonic image. Path status.

Limited to the need for large-volume, high-cost ultrasound imaging devices and professional medical staff diagnosis, the existing vascular access status monitoring is not suitable for home self-monitoring, and is not conducive to early detection of poor vascular access.

The main object of the present invention is to provide a portable vascular access condition monitoring device, which can replace the ultrasonic image module for vascular access state monitoring by using a small-sized, low-cost vibration sensing module.

To achieve the above object, the present invention provides a portable vascular access condition monitoring device comprising a measuring device and a monitoring module. The measuring device comprises a vibration sensing module and a communication module electrically connected to the vibration sensing module. The vibration sensing module senses a vibrational data induced by blood flow in a portion of a subject's vascular access. The communication module is used for transmitting data externally. The monitoring module controls an electronic device connected to the communication module of the measuring device to read a vibration critical data of a corresponding portion from a memory, and determines a corresponding portion according to the vibration data and the vibration critical data. A vibration assessment indicator of the state.

The portable vascular access condition monitoring device of the invention has the advantages of small size, portability and low cost, and is suitable for monitoring the state of the home vascular access.

DETAILED DESCRIPTION OF THE INVENTION A preferred embodiment of the present invention will be described in detail with reference to the drawings.

2 is a structural diagram of a portable vascular access state monitoring device according to a first embodiment of the present invention.

The portable vascular access state monitoring device (hereinafter referred to as monitoring device) 2 of the present embodiment mainly includes a measuring device 20 and a monitoring module 220. The measuring device 20 includes a vibration sensing module 200 and a communication module 202.

The vibration sensing module 200 (such as one or more three-axis accelerometers, force sensors or other types of vibration sensors). It is used to sense the blood flow induced vibration of a specific part of the blood vessel passage (such as an artery, vein, arteriovenous fistula or arteriovenous blood vessel) of the subject, and generate vibration data corresponding to the part.

Communication module 202 (such as Bluetooth network module, ZigBee network module, Wi-Fi network module, infrared network module and other wireless transmitters or serial communication modules, audio source lines, USB modules, etc. The wired transmitter is used to connect the electronic device 22 and transmit data (such as vibration data) to the electronic device 22.

In one embodiment, the communication module 202 can include a set of microcontrollers (MCUs) for controlling the measurement device 20 and performing data signal processing.

A monitoring module 220 (such as a microcontroller or a processor) is disposed in the electronic device 22 for controlling the electronic device 22. Specifically, the monitoring module 220 can control the electronic device 22 to receive the vibration data from the communication module 202, and determine an evaluation index corresponding to the state of the specific portion of the vascular access.

It is worth mentioning that, because each subject's blood flow rate and blood pressure are different, the state of the vascular access may be judged according to the vibration induced by blood flow, which may cause errors in the diagnosis results, which may delay the patient's treatment. . therefore. The invention does not directly provide a diagnosis result according to the sensed data, but determines the evaluation index of the subject to be tested at this time, and the subject (or the monitoring device 2 automatically) determines the blood vessel according to the long-term change of the evaluation index. The state of the path.

It is worth mentioning that in the normal vascular access (no stenosis, no blockage), the flow of blood at the vascular junction produces a continuous tremor (Thrill). When the vascular access is blocked or stenotic, blood flow can only induce pulsation or weakened tremor. The present invention is an evaluation index for determining whether or not the tremor is disappeared or weakened by analyzing vibration data induced by blood flow, thereby determining the state of the vascular access.

It is worth mentioning that although in general cognition, the state of the blood pathway is only blocked and unobstructed, the present invention considers that the aforementioned judgment error sets a set of specified ranges consisting of a plurality of consecutive values (eg, 1 to 10), and set the two ends of the specified range as positive indicators (such as the closer to 1 indicates the higher the probability of non-blocking) and the negative indicator (such as the closer to 10 indicates the higher the possibility of blocking). Therefore, when the subject's multiple evaluation indicators change toward the negative index (such as from 6 to 9), it can be judged that the state of the blood pathway may be poor; when the subject's multiple evaluation indicators are maintained When fixed (if maintained), it can be judged that this evaluation index is the normal value of this subject.

Compared with the prior art, it is required to use a large-volume, high-cost ultrasonic image capturing device to perform vascular access state monitoring in conjunction with professional diagnosis. The portable vascular access state monitoring device of the present invention has a volume by using only a vibration sensing module. Small, easy to carry and cheap, and can automatically determine the evaluation index of vascular access, and is suitable for home vascular access status monitoring.

Continuing to refer to FIG. 2, FIG. 3A and FIG. 3B, FIG. 3A is a schematic diagram of the use of the portable vascular access state monitoring device for the arteriovenous artificial blood vessel according to the second embodiment of the present invention, and FIG. 3B is a view showing the state of the portable vascular access according to the second embodiment of the present invention. The monitoring device is used for the use of arteriovenous fistula.

In the present embodiment, the measuring device 20 can be used to measure blood flow induced vibration data of any part of the blood vessel passage of the subject. Moreover, the electronic device 22 is a device dedicated to the measuring device 20 (ie, the measuring device 20 and the electronic device 22 must be used in a set), and the measuring device 20 is wired. Moreover, in the present example, the measuring device 20 further includes a patch structure for detachably attaching to the portion.

As shown in FIGS. 3A and 3B, the subject can attach the measuring device 20 to a specific portion of the blood vessel passage of the subject (such as the position of the measuring device 20, which is located in FIG. 3A). The location of the venous artificial blood vessel, in the position of the arteriovenous fistula in FIG. 3B, is up to a first measurement time (eg, 30 seconds) to allow the measurement device 20 to continuously sense the blood flow induced vibration data at the site. Alternatively, the subject can also attach the measuring device 20 to another portion of the subject's vascular access (ie, the position of the measuring device 20', which is located at the position of the vein in FIGS. 3A and 3B). The second measurement time (e.g., 50 seconds) is such that the measurement device 20 continues to sense another vibrational data induced by blood flow at another location.

Moreover, the measuring device 20 can transmit the sensed vibration data to the electronic device 22 for analysis processing immediately or after the sensing is completed.

Finally, the monitoring module 220 controls the electronic device 22 to receive the vibration data (ie, the vibration data of each part), obtain the vibration critical data corresponding to each part, and determine the corresponding subject according to each vibration data and the corresponding vibration critical data. The vibration assessment index of the current state of each part of the vascular access.

Although the monitoring module is implemented in a hardware manner in the foregoing embodiments, it is not limited thereto. In another embodiment, the monitoring module can also be implemented in a software manner.

Please refer to FIG. 4, which is a structural diagram of a portable vascular access state monitoring device according to a third embodiment of the present invention. The portable vascular access condition monitoring device 4 (hereinafter referred to as the monitoring device 4), the measuring device 40, the vibration sensing module 400, the communication module 402, and the electronic device 42 of the embodiment shown in FIG. 4 are respectively implemented as shown in FIG. The monitoring device 2, the measuring device 20, the vibration sensing module 200, the communication module 202, and the electronic device 22 are the same or similar, and are not described herein again.

In one embodiment, the measuring device 40 further includes a radio module 404 (such as one or more omnidirectional microphones, directional microphones or other types of microphones) electrically connected to the communication module 402. The sound module 404 is configured to collect sounds induced by blood flow in a specific part of the blood vessel passage of the subject, and generate corresponding sound data, wherein the sound frequency range sensed by the sound module 404 is similar or falls on the person. The ear can hear the frequency range.

In one embodiment, the radio module 404 includes an audio amplifier and/or an audio filter (not shown). The audio amplifier is used to amplify the volume of the sensed sound data, and the audio filter is used to filter the noise of the sensed sound data. Furthermore, since the sound induced by the blood flow is rather weak, and the measurement environment may have a large number of interfering sound sources, the present invention preprocesses the sensed sound data by using an audio amplifier and an audio filter, thereby effectively amplifying the volume and filtering In addition to noise, improve the accuracy of subsequent judgments.

In one embodiment, the measuring device 40 further includes a blood flow rate sensing module 406 electrically connected to the communication module 402. The blood flow rate sensing module 406 is configured to sense a flow rate of blood flow at a specific portion of the blood vessel passage of the subject and generate corresponding flow rate data. Preferably, the blood flow rate sensing module 406 is an optical flow meter (such as one or more laser Doppler tachometers).

Moreover, the electronic device 42 of the embodiment is a general-purpose device (such as a smart phone, a notebook computer, a wearable device, a cloud host, or other types of multifunctional electronic devices), and includes a transceiver 424, a memory 426, and a human-machine interface. 428 and a processor 422 electrically connected to the above components.

The transceiver 424 and the communication module 402 use compatible communication technologies (such as Bluetooth communication) to communicate with each other. Memory 426 is used to store data. The human interface 428 (such as an indicator light, a horn, a microphone, a button, a touch screen, or any combination of the above) is used to accept operations or output data. The processor 422 is used to control the electronic device 42.

Moreover, the monitoring module 420 of the embodiment is a computer program stored in the non-transitory memory 426, and includes a computer executable code. After the processor 422 executes the code of the monitoring module 420, the electronic device 42 can be controlled to perform the steps of the vascular path state monitoring method according to various embodiments of the present invention with the measuring device 40.

Please refer to FIG. 4 and FIG. 6 simultaneously. FIG. 6 is a flowchart of a method for monitoring a state of a blood vessel path according to a first embodiment of the present invention.

In the embodiment of FIG. 6 , the subject first attaches the measuring device 40 to the measured portion of the vascular access, so that the measuring device 40 senses the vibration data of the portion via the vibration sensing module 400, and The vibration data is externally transmitted via the communication module 402 (step S100).

Next, the electronic device 42 reads the pre-stored vibration critical data 430 from the memory 426 (step S102). In one embodiment, the memory 426 stores a plurality of vibration critical data 430, each of which corresponds to a different portion of the vascular access, and the subject can set the current measured portion via the human-machine interface 428. The electronic device 42 reads the vibration critical data 430 corresponding to the measured portion by itself.

Finally, the electronic device 42 determines a vibration evaluation index corresponding to the state of the portion based on the received vibration data and the read vibration critical data (step S104).

In one embodiment, the vibration critical data is a reference vibration amplitude of a specific portion of the blood vessel passage of the subject in a normal state, and the electronic device 42 analyzes a plurality of amplitudes of the vibration data and calculates a set of representative amplitudes (eg, multiple amplitudes). The maximum or average value is compared with the calculated vibration amplitude data. If the representative amplitude is smaller than the vibration critical data, the electronic device 42 sets the vibration evaluation index to be a negative negative indicator. Otherwise, the electronic device 42 sets the vibration evaluation index as a bias forward indicator.

The vascular access state monitoring method of the present invention can effectively measure the vibration of the vascular access and provide a vibration evaluation index of the vascular access, and the subject can estimate the state of the vascular access.

Please refer to FIG. 4 and FIG. 7 simultaneously. FIG. 7 is a flowchart of a method for monitoring a state of a blood vessel path according to a second embodiment of the present invention.

In the embodiment of FIG. 7, the monitoring device 4 can simultaneously measure the vibration data, the sound data, and the flow rate data of the same portion of the blood vessel passage of the subject, and determine the vibration evaluation index, the sound evaluation index, and the flow rate evaluation index, and The determined vibration assessment indicators, sound assessment indicators, and flow rate assessment indicators further determine the overall assessment indicators for this location.

It should be noted that, in the present embodiment, the monitoring device 4 measures the vibration data, the sound data, and the flow rate data of the same portion of the blood vessel passage of the subject at the same time, but is not limited thereto.

In another embodiment, the monitoring device 4 can measure only one or two of the vibration data, the sound data, and the flow rate data, and determine the corresponding evaluation index according to the measured data. For example, the monitoring device 4 can measure only the vibration data and the sound data, determine the vibration evaluation index and the sound evaluation index, and determine the overall evaluation index according to the determined vibration evaluation index and the sound evaluation index.

In the embodiment of FIG. 7, the subject can attach the measuring device 40 to the measured portion of the vascular access, so that the measuring device 40 senses the blood flow induced sensing data of the measured portion (step S200). .

In one embodiment, the measurement device 40 senses the vibration data of the portion via the vibration sensing module 400, and senses the sound data of the portion through the sound module 404, and senses the portion through the blood flow rate sensing module 406. The flow rate data is sent to the externally sensed vibration data, sound data, and flow rate data via the communication module 402.

Next, the electronic device 42 reads the critical data corresponding to the portion from the memory 426 (step S202), such as the vibration critical data 430, the sound critical data 432, and the flow rate critical data 434.

In one embodiment, the memory 426 stores a plurality of pieces of vibration critical data 430, a plurality of sound critical data 432, and a plurality of flow rate critical data 434. Each of the vibration critical data 430, each of the sound critical data 432, and each of the flow rate critical data 434 are respectively corresponding to different parts of the vascular access. The electronic device 42 reads the vibration critical data 430, the sound critical data 432, and the flow rate critical data 434 corresponding to the current measured portion.

In one embodiment, prior to performing the measurement, the medical personnel can operate a more sophisticated instrument (such as a higher sensitivity vibration sensing module) to measure various parts of the vascular access of the same subject to obtain the respective parts. The vibration data, the sound data, and the flow rate data in the normal state are used as the vibration critical data 430, the sound critical data 432, and the flow rate critical data 434 of each part.

In one embodiment, the memory 426 stores a plurality of sample materials (eg, a plurality of template vibration data 436, a plurality of template sound data 438, and a plurality of template flow data 440), wherein the template data respectively correspond to different parts of the vascular access and Different physiological parameters (such as height, weight, age or any combination of the above). The electronic device 42 selects the corresponding template data according to the measured part and the physiological parameter of the subject as the critical data (such as the vibration critical data 430, the sound critical data 432, and the flow rate critical data 434).

In one embodiment, the memory 426 stores historical data (eg, historical vibration data 441, historical sound data 444, and historical velocity data 446) that the subject has previously measured. This historical data is a specific part of the corresponding vascular access. The electronic device 42 selects historical data corresponding to the same portion as the critical data (such as the vibration critical data 430, the sound critical data 432, and the flow rate critical data 434).

Next, the electronic device 42 performs time domain to frequency domain conversion processing on the received sensing data to obtain corresponding spectrum data (step S204).

In an embodiment, the electronic device 42 may further perform a band pass filtering process on the generated spectral data to filter a noise frequency outside a specific frequency (such as a frequency corresponding to the tremor).

In an embodiment, the electronic device 42 can perform time domain to frequency domain conversion processing (such as fast Fourier transform, Laplacian transform, or discrete wavelet transform) on the received vibration data, sound data, and velocity data to obtain a correspondence. The vibration spectrum data, the sound spectrum data and the flow rate spectrum data are not limited thereto.

In another embodiment, the electronic device 42 performs time domain to frequency domain conversion processing only on the received vibration data and sound data to obtain corresponding vibration spectrum data and sound spectrum data, without performing time domain on the flow rate data. To frequency domain conversion processing.

Next, the electronic device 42 performs pulse analysis processing on the generated spectrum data to obtain pulse data (step S206).

For example, the electronic device 42 performs time domain to frequency domain conversion processing on the vibration data, the sound data, and the flow rate data, and the electronic device 42 identifies the frequency with the highest amplitude (the fundamental frequency) in the sound spectrum data, the vibration spectrum data, and the flow rate spectrum data, respectively. Then, the identified frequency and its multiplication (harmonic) are respectively set as the vibrational arterial spectrum data, the sound pulse spectrum data, and the flow rate pulse spectrum data.

Next, the electronic device 42 filters the pulse data from the spectral data to obtain pulseless spectrum data (step S208). In one embodiment, the electronic device 42 filters the vibrational arterial spectrum data, the sound pulse spectrum data, and the flow rate pulse spectrum data from the sound spectrum data, the vibration spectrum data, and the flow rate spectrum data to obtain the vibration-free pulse spectrum data and the sound respectively. Pulse spectrum data and flow rate without pulse spectrum data.

Next, the electronic device 42 performs frequency domain to time domain conversion processing on the pulseless spectrum data to obtain pulseless time domain data (step S210).

In an embodiment, the electronic device 42 performs frequency domain to time domain conversion processing on the vibration-free pulse spectrum data, the sound pulse-free spectrum data, and the flow rate pulse-free spectrum data to obtain the vibration-free pulse time domain data and the sound pulse-free time domain, respectively. Data and flow rate without pulse time domain data.

Next, the electronic device 42 determines the evaluation index based on the pulseless time domain data and the critical data acquired in step S202 (step S212).

In one embodiment, the electronic device 42 determines the vibration evaluation index according to the vibration-free pulse time domain data and the vibration critical data 430, and determines the sound evaluation index according to the sound pulse-free time domain data and the sound critical data 432, and the pulse-free time domain according to the flow rate. The data and flow rate threshold data 434 determines the flow rate assessment indicator.

For example, if the indicator range is 1 to 10 (10 means the highest blocking probability, 1 is the lowest). When the non-pulse time domain data is more similar to the critical data, the more the evaluation index is determined to be toward 1, the more dissimilar, the more biased toward 10, and vice versa.

Thereby, the present invention can determine an accurate evaluation index.

In an embodiment, the electronic device 42 may further determine an overall evaluation index of the tested part according to the determined vibration evaluation index, the sound index, and the flow rate evaluation index.

For example, the range of each evaluation index (ie, vibration evaluation index, sound index, and flow rate evaluation index) is 1 to 10 (10 indicates the highest blocking probability and 1 is the lowest). When all (or more than half) of the evaluation indicators are negative indicators (such as any of the values between 7 and 10), the electronic device 42 may determine that the overall evaluation indicator is "abnormal". When all (or more than half) of the evaluation indicators are positive indicators (such as any of the values between 1-4), the electronic device 42 may determine that the overall evaluation indicator is "normal." When all (or more than half) of the evaluation indicators are neutral indicators (such as any of the values between 5 and 6), the electronic device 42 may determine that the overall evaluation indicator is "unknown."

In an embodiment, the critical data obtained in step S202 is spectral data. Moreover, in the embodiment, the electronic device 42 does not perform step S210, but directly executes step S212 to determine the evaluation index according to the generated pulse-free spectrum data and the critical data.

Please refer to FIG. 4 and FIG. 8 simultaneously. FIG. 8 is a flowchart of a method for monitoring a state of a blood vessel path according to a third embodiment of the present invention.

In the embodiment of FIG. 8, the monitoring device 4 can measure the vibration data of the plurality of parts of the vascular passage of the subject, determine the vibration evaluation index of each part, and further determine the vascular access according to the determined plurality of vibration evaluation indicators. The overall vibration assessment indicator.

It is worth mentioning that although in this embodiment, the overall vibration evaluation index is determined based on the vibration data of a plurality of parts, it is not limited thereto.

In another embodiment, the monitoring device 4 can simultaneously measure the vibration data, the sound data, and the flow rate data of each part, and determine the vibration evaluation index, the sound evaluation index, and the flow rate evaluation index of each part according to the measured data, and According to the determined vibration evaluation index, sound evaluation index and flow rate evaluation index of each part, the overall vibration evaluation index, the overall sound evaluation index and the overall flow rate evaluation index of the vascular access are respectively determined.

In the embodiment of FIG. 8 , the subject may first attach the measuring device 40 to the first portion of the vascular access for the measuring device 40 to sense the first vibration of the first portion via the vibration sensing module 400 . Information (step S300).

Next, the electronic device 42 determines whether the sensing of the portion is ended (step S302), if the preset measurement time (eg, 10 seconds) has been continuously sensed. If the electronic device 42 determines that the sensing of the portion has not ended, step S300 is performed again to continue sensing.

If the electronic device 42 determines to end the sensing of the portion, it is further determined whether all the parts have been measured (step S304). In one embodiment, the electronic device 42 determines that a plurality of parts (such as the first part, the second part, and the third part) of the blood vessel passage of the subject have been measured and obtained sensing data of each part (eg, The first vibration data, the second vibration data, and the third vibration data are used to determine that all parts have been measured.

If the electronic device 42 determines that the location is not measured, an alert is issued via the human interface 428 to instruct the subject to replace the measurement site (step S318) and perform the sensing again after the measurement site is replaced.

If the electronic device 42 determines that all the parts have been measured, performing time domain to frequency domain conversion processing on the received sensing data to obtain corresponding spectrum data (step S306). In an embodiment, the electronic device 42 performs time domain to frequency domain conversion processing on the first vibration data, the second vibration data, and the third vibration data to obtain first vibration spectrum data, second vibration spectrum data, and third vibration spectrum. data.

Next, the electronic device 42 performs pulse analysis processing on the generated spectral data to obtain pulse data (step S308), and filters the pulse data from the spectral data (step S310). In an embodiment, the electronic device 42 performs pulse analysis processing on the first vibration spectrum data, the second vibration spectrum data, and the third vibration spectrum data to obtain first vibrational beat spectrum data, second vibrational beat spectrum data, and third vibration. The pulse spectrum data is filtered out from the first vibration spectrum data, the second vibration spectrum data, and the third vibration spectrum data, respectively, the first vibrational artery spectrum data, the second vibrational artery spectrum data, and the third vibrational artery spectrum data are obtained. A vibration-free pulse spectrum data, a second vibration-free pulse spectrum data, and a third vibration-free pulse spectrum data.

Next, the electronic device 42 performs frequency domain to time domain conversion processing on the frequency domain data of the filtered pulse data to obtain time domain data (step S312). In an embodiment, the electronic device 42 performs frequency domain to time domain conversion processing on the first vibration pulse-free spectrum data, the second vibration pulse-free spectrum data, and the third vibration pulse-free spectrum data to obtain a first vibration-free pulse time domain. Data, second vibration pulse-free time domain data, and third vibration pulse-free time domain data.

Next, the electronic device 42 determines the evaluation index based on the generated time domain data (step S314). In an embodiment, the electronic device 42 reads the first vibration critical data, the second vibration critical data, and the third vibration critical data from the memory 426, and determines the first vibration-free time domain data and the first vibration critical data according to the first vibration. A vibration evaluation index determines a second vibration evaluation index according to the second vibration pulseless time domain data and the second vibration critical data, and determines the third vibration evaluation index according to the third vibration pulseless time domain data and the third vibration critical data.

Further, the electronic device 42 further determines an overall evaluation index of the vascular access according to the first vibration evaluation index, the second vibration evaluation index, and the third vibration evaluation index.

Finally, the electronic device 42 updates the critical data in the memory 426 according to the result of the evaluation (step S316).

In an embodiment, the electronic device 42 can use the generated information according to the evaluation indicators (such as the first vibration evaluation index, the second vibration evaluation index, the third vibration evaluation index, and the overall evaluation index) that are determined this time (such as the first The vibration-free pulse-time domain data, the second vibration-free pulse-time domain data, and the third vibration-free pulse-time domain data) update the critical data, the template data, or the historical data stored in the memory 426 to make the critical data, the template data, or the history. The data is closer to the subject's recent physiological characteristics.

Continuing to refer to FIG. 4 and FIG. 5A simultaneously, FIG. 5A is a schematic diagram of the use of the portable vascular access state monitoring device for the arteriovenous artificial blood vessel according to the fourth embodiment of the present invention.

In the present embodiment, the monitoring device 40 separately obtains and compares vibration data, sound data, and flow rate data induced by blood flow in different parts of the subject. Moreover, the electronic device 42 is a smart phone equipped with a monitoring module 420 (in this embodiment, an application), and uses the Bluetooth communication technology to wirelessly connect the communication module 402 of the measuring device 40 via the transceiver 424.

As shown in FIG. 5A, the subject can attach the measuring device 40 to the first portion of the subject's vascular access (ie, the position of the measuring device 40) for the first measurement time (eg, 20). Second, the measurement device 40 continuously senses the first vibration data, the first sound data, and the first flow rate data induced by the blood flow of the first portion and transmits the first vibration data to the electronic device 42 for analysis processing.

Next, the subject removes the measuring device 40 from the first portion, and attaches the removed measuring device 40 to the second portion of the subject's vascular access (position 50 shown in FIG. 5A) to the second position. The measuring time (for example, 20 seconds) is performed to cause the measuring device 40 to continuously sense the second vibration data, the second sound data and the second flow rate data induced by the blood flow of the second portion and transmit the data to the electronic device 42 for analysis processing.

Next, the subject removes the measuring device 40 from the second portion, and attaches the removed measuring device 40 to the third portion of the subject's vascular access (position 52 shown in FIG. 5A) to the third position. The measuring time (eg, 20 seconds) is performed to cause the measuring device 40 to continuously sense the third vibration data, the third sound data, and the third flow rate data induced by the blood flow of the third portion and transmit the data to the electronic device 42 for analysis processing.

Finally, the electronic device 42 receives the first vibration data, the second vibration data, the third vibration data, the first sound data, the second sound data, the third sound data, the first flow rate data, the second flow rate data, and The third flow rate data is processed to determine the corresponding evaluation indicator.

Continuing to refer to FIG. 4 and FIG. 5B, FIG. 5B is a schematic diagram of the use of the portable vascular access state monitoring device for the arteriovenous artificial blood vessel according to the fifth embodiment of the present invention. In the embodiment, the sound collection module 404 includes a first sound receiver 600, a second sound receiver 620, and a third sound receiver 640. The vibration sensing module 402 includes a first vibration sensor 602, a second vibration sensor 622, and a third vibration sensor 642. The communication module 402 includes a first transmitter 604, a second transmitter 624, and a third transmitter 644. The blood flow rate sensing module includes a first blood flow rate sensor 606, a second blood flow rate sensor 626, and a third blood flow rate sensor 646.

Also, monitoring device 40 includes monitoring patches 60-64. The monitoring patch 60 is provided with a first sound receiver 600, a first vibration sensor 602, a first transmitter 604, and a first blood flow rate sensor 606. The monitoring patch 62 is provided with a second sound 620, a second vibration sensor 622, a second transmitter 624, and a second blood flow rate sensor 626. The monitoring patch 64 is provided with a third sound receiver 640, a third vibration sensor 642, a third transmitter 644, and a third blood flow rate sensor 646.

As shown in FIG. 5B, when performing the measurement, the test subject can attach the monitoring patch 60 to the first portion of the vascular passage of the subject, and attach the monitoring patch 62 to the second portion outside the vascular access, and the monitoring will be performed. The patch 64 is attached to a third portion remote from the vascular access. Then, the subject waits for a preset measurement time (for example, 30 seconds).

During the waiting period, the monitoring patch 60 senses the first sound data via the first sound receiver 600, senses the first vibration data via the first vibration sensor 602, and senses the first flow rate via the first blood flow rate sensor 606. The data is transmitted to the electronic device 42 via the first transmitter 604 for analysis processing. Similarly, the monitoring patch 62 senses the second sound data via the second sound 620, senses the second vibration data via the second vibration sensor 622, and senses the second flow rate data via the second blood flow rate sensor 626. And transmitting the sensed data to the electronic device 42 via the second transmitter 624 for analysis processing. The monitoring patch 64 senses the third sound data via the third sound 640, senses the third vibration data via the third vibration sensor 642, and senses the third flow rate data via the third blood flow sensor 646, and via The third transmitter 644 transmits the sensed data to the electronic device 42 for analysis processing.

Finally, the electronic device 42 processes the received data and determines an evaluation indicator.

The present invention can effectively shorten the measurement time by performing measurement using a plurality of monitoring patches at the same time.

It is worth mentioning that although the device of FIGS. 5A and 5B is for a vascular access including an arteriovenous artificial blood vessel, it can also be used for a vascular access including an arteriovenous fistula, and is not limited thereto.

The above is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention. Therefore, equivalent changes to the scope of the present invention are included in the scope of the present invention. Bright.

10‧‧‧ vein

12‧‧‧arterial

14‧‧‧Arteriovenous Vascular

16‧‧‧Arteriovenous fistula

2, 4‧‧‧ portable vascular access condition monitoring device

20, 20', 40‧‧‧ measuring devices

200, 400‧‧‧ vibration sensing module

202, 402‧‧‧Communication Module

22, 42‧‧‧ Electronic devices

220, 420‧‧‧ Monitoring Module

404‧‧‧ Radio Module

406‧‧‧ Blood Flow Sensing Module

422‧‧‧ processor

424‧‧‧ transceiver

426‧‧‧ memory

428‧‧‧Human Machine Interface

430‧‧‧Vibration critical data

432‧‧‧Sound critical information

434‧‧‧Flow rate critical data

436‧‧‧Model vibration data

438‧‧‧Fang sound data

440‧‧‧Model flow rate data

442‧‧‧Historical vibration data

444‧‧‧ Historical sound data

446‧‧‧ Historical flow rate data

50, 52‧‧‧ position

60‧‧‧First measuring device

600‧‧‧first radio

602‧‧‧First vibration sensor

604‧‧‧First transmitter

606‧‧‧First blood flow sensor

62‧‧‧Second measuring device

620‧‧‧second radio

622‧‧‧Second vibration sensor

624‧‧‧Second transmitter

626‧‧‧Second blood flow sensor

64‧‧‧ third measuring device

640‧‧‧ Third Radio

642‧‧‧ Third vibration sensor

644‧‧‧ Third Transmitter

646‧‧‧ Third blood flow sensor

S100-S104‧‧‧First monitoring step

S200-S212‧‧‧Second monitoring step

S300-S318‧‧‧ third monitoring step

Fig. 1A is a schematic view of an arteriovenous artificial blood vessel.

Figure 1B is a schematic illustration of an arteriovenous fistula.

2 is a block diagram of a portable vascular access state monitoring device according to a first embodiment of the present invention.

3A is a schematic view showing the use of a portable vascular access state monitoring device for an arteriovenous artificial blood vessel according to a second embodiment of the present invention.

3B is a schematic view showing the use of a portable vascular access state monitoring device for an arteriovenous fistula according to a second embodiment of the present invention.

4 is a block diagram of a portable vascular access state monitoring device according to a third embodiment of the present invention.

FIG. 5A is a schematic view showing the use of a portable vascular access state monitoring device for an arteriovenous artificial blood vessel according to a fourth embodiment of the present invention.

FIG. 5B is a schematic view showing the use of a portable vascular access state monitoring device for an arteriovenous artificial blood vessel according to a fifth embodiment of the present invention.

Fig. 6 is a flow chart showing a method for monitoring a state of a vascular access according to a first embodiment of the present invention.

Fig. 7 is a flow chart showing a method for monitoring a state of a blood vessel path according to a second embodiment of the present invention.

Fig. 8 is a flow chart showing a method of monitoring a state of a blood vessel path according to a third embodiment of the present invention.

Claims (8)

A portable vascular access condition monitoring device, comprising: a measuring device, comprising: a vibration sensing module, sensing a vibration data induced by blood flow of a portion of a blood vessel passage of a subject; and a communication module Electrically connecting the vibration sensing module for externally transmitting data; and a monitoring module for controlling an electronic device of the communication module connected to the measuring device to read a corresponding part from a memory The vibration critical data is determined according to the vibration data and the vibration critical data to determine a vibration evaluation index corresponding to the state of the location. The portable vascular access condition monitoring device according to claim 1, wherein the vibration critical data is an amplitude value, and the monitoring module is configured to: when a maximum value or an average value of the plurality of vibration amplitudes of the vibration data is smaller than the vibration critical data Determine the vibration assessment indicator as a negative indicator. The portable vascular access condition monitoring device of claim 1, wherein the monitoring module performs a time domain to frequency domain conversion process on the vibration data to obtain a vibration spectrum data, and performs a pulse analysis process on the vibration spectrum data. A spectrum of the arterial beat spectrum is obtained, and the vibrational beat spectrum data is filtered out from the vibration spectrum data to obtain a vibration-free pulse spectrum data, and the vibration evaluation index is determined according to the vibration-free pulse spectrum data and the vibration critical data. The portable vascular access condition monitoring device according to claim 3, wherein the monitoring module performs a frequency domain to time domain conversion process on the vibration pulseless spectrum data to obtain a vibration pulseless time domain data, and then according to the vibration The pulse-free time domain data and the vibration critical data determine the vibration evaluation index. The portable vascular access condition monitoring device of claim 1, wherein the memory stores a plurality of template vibration data, wherein the monitoring module selects one of the plurality of template vibration data according to a physiological parameter of the subject One is used as the critical information of the vibration. The portable vascular access condition monitoring device according to claim 1, wherein the memory stores a historical vibration data of the subject, and the monitoring module reads the historical vibration data of the subject as the vibration critical data. . The portable vascular access condition monitoring device of claim 1, wherein the measuring device further comprises a patch structure for detachably attaching to the portion. The portable vascular access condition monitoring device according to claim 1, wherein the vibration sensing module senses a first vibration data induced by blood flow of a first portion of the vascular passage of the subject and a first a second vibration data induced by blood flow in the two parts; the monitoring module controls the electronic device to read from the memory a first vibration critical data corresponding to the first part and a second corresponding to the second part The vibration critical data determines a first vibration evaluation index corresponding to the state of the first portion according to the first vibration data and the first vibration critical data, and determines the second corresponding to the second vibration data and the second vibration critical data a second vibration evaluation index of the state of the part, and determining an overall evaluation index according to the first vibration evaluation index and the second vibration evaluation index.