TW201739911A - A device of preparing Cell blocks - Google Patents

Abstract

A device of preparing Cell blocks, which is made up of two soft cannulas, one outer soft cannula, one inner soft cannula and a stick. The outer soft cannula could be made by any soft material in any shape. The inner soft cannula is elongated, and the feature of the cannula is to take cytopathology diagnostic material for preparing cell blocks. By holding the material together throughout the procedure, and hardening the cell block so that it can be easily transferred without losing diagnostic material.

Description

Cell mass making device

This creation class effectively concentrates the cells of the liquid pathology and liquid-based cytology pathology in the field of cytopathology into a high-density mass.

At present, it is known that a liquid sample and a liquid-based cytological pathological specimen in the field of cytopathology are used to condense cells into a cell pellet by centrifugal force, but sometimes it is impossible to use the naked eye after centrifugation. It was observed, and often need to use a variety of tools or the manner aggregated precipitate taken to maintain cell number or cell concentration or integrity ^{(eg: agar, Histogel TM, gelatin albumin} , collodion, pre-gelatinized starch, sodium alginate, gelatin Foam, polyvinyl alcohol foam, acentone-melted paraffin technique, etc., followed by histopathological methods to make a cell block of paraffin sections, except for the collodion method which is particularly emphasized for a small amount of samples. There is a problem that the cell content is too low or needs to be stirred to cause cell dispersion or cell loss, and the proper cell mass cannot be obtained, especially when the liquid-based cytological pathological sample is used.

The present invention provides a cell briquetting device, which exhibits a slim pattern in a pattern different from that formed by a collodion method, and uses a slender shape of a smaller volume as an inner cup when the liquid is in the pathological field. When the sample and liquid-based cytology pathology are centrifuged, the cells can It is enough to stack up the bottom of the cup to form a high-density mass visible to the naked eye, and the cup outside the creation is made of soft rubber, which can eliminate the step of converting the sediment into the container required for the histopathological method. The cell agglomerate device can be placed directly into the histopathological examination container, thereby reducing the problem of cell loss or dispersion or incompleteness caused by the conversion of the container or the residual test tube wall of the cell sample. In addition, when the subsequent cell mass is embedded, the orientation can be fixed and the cell density of each slice is the same. The raw materials are easy to obtain and reduce the cost of consumables.

1‧‧‧Soft rubber outer cup

2‧‧‧Slim inner cup style

3‧‧‧ High-density sediment visible to the naked eye

Figure 1 is a front perspective view of the creation; Figure 2 is a front perspective view of the use state of the creation; and Figure 3 is an isometric perspective view of the use state of the creation;

Please refer to Figure 1, Figure 2 and Figure 3. The soft rubber cup provided by this creation includes a soft rubber outer cup 1, and a slim inner cup style 2.

The elongated inner cup style 2 provided by the present invention can precipitate a cell at the bottom of the soft plastic cup to form a high-density sediment visible to the naked eye in the liquid pathology and liquid-based cytological pathological centrifugation in the field of cytopathology (see Figures 2 and 3), and can be placed in the container required for histopathological methods without any other substances being stirred or transferred again.

1‧‧‧Soft rubber outer cup

2‧‧‧Central slim inner cup style

3‧‧‧ High-density sediment visible to the naked eye

Claims (3)

A cell mass making device comprises: an inner cup, which is an elongated type of cone for holding tissues such as a sample and a cell; and an outer cup having a shape of a cone for a carrier of the inner cup. The inner cup according to the item 1 has a shape in which the tissues such as the specimen and the cells are centrifuged, and the tissues are stacked on the bottom of the inner cup to form a mass, and the shape can embed the subsequent cell mass. Fix the orientation and make the cell density of each slice the same. The cup as described in item 1 does not adhere to the cell mass described in claim 2, and can be directly used for the placement of a histopathological examination container to reduce the residual test tube due to the conversion container or the cell sample. The problem of cell loss or dispersion or incompleteness caused by the wall.