TW201718769A - Hydrogel composition and hydrogel contact lenses made of the composition - Google Patents

Abstract

The instant disclosure provides a hydrogel composition for manufacturing hydrogel contact lens. The hydrogel composition includes a hydrophilic monomer, blue light-blocking monomer, a crosslinker and an initiator. The hydrophilic monomer is in a range from 30 to 99.68 parts by weight. The blue light-blocking monomer is in a range from 0.02 to 0.5 parts by weight and includes a yellow dye. The crosslinker is in a range from 0.1 to 1 parts by weight. The initiator is in a range from 0.2 to 2 parts by weight.

Description

Water gel composition and water gel lens prepared by the same

This invention relates to a water gel composition, and more particularly to a water gel composition that blocks blue light.

Since the contact lens made of hydrogel has a good moisturizing function, even if worn for a long time, the cornea can have sufficient water content, and it is not easy to cause symptoms of eye discomfort due to dryness of the cornea. Therefore, water gel has become one of the preferred components of contact lens lenses.

In the past two decades, many electronic display devices, such as TV screens, computer screens, tablets, and mobile phones, use light emmiting diodes (LEDs) as light sources, and blue light emitted by LEDs (wavelengths 380 nm to 500 nm). ) It is easy to cause eye diseases. In the case of long-term use of a tablet or a mobile phone, the eye may be damaged by the retina due to prolonged exposure to blue light, and may even cause early detection of cataract and macular lesions.

However, there are still high water-containing contact lenses on the market that can block blue light to protect the eyes. Therefore, there is a great need for a water gel lens that can simultaneously have good blue light absorbing effect and high water content.

In view of the problems faced by the prior art, the present invention discloses a water gel composition capable of isolating blue light, and the water gel lens produced by the invention has the effects of high water content and blue light isolation.

The present invention provides a water gel composition for preparing a water gel lens. The hydrocolloid composition comprises a hydrophilic monomer, a blue blocking monomer, a crosslinking agent, and an initiator. Wherein, the hydrophilic monomer is 30 to 99.68 parts by weight; the blocking blue light monomer is 0.02 to 0.5 parts by weight, and it contains a yellow dye; the crosslinking agent is 0.1 to 1 part by weight; and the initiator is 0.2 to 2 parts by weight.

In various embodiments of the invention, the hydrophilic monomer is from 96.5 to 99.68 parts by weight.

In various embodiments of the present invention, the water gel composition further comprises a silicone compound selected from the group consisting of a ruthenium monomer, a ruthenium high polymer, and a ruthenium prepolymer, and the ruthenium compound is 5 to 59 parts by weight, and the hydrophilic monomer is 30 to 60 parts by weight.

In various embodiments of the invention, the fluorene monomer has the structure of formula (1): Where V ₁ is , or , L ₁ is an alkylene group of C3~C7 or , R ₁ is methyl or Where * is the bonding position in equation (1).

In various embodiments of the invention, the cerium high polymer has the structure of formula (2): Wherein L ₂ is an alkylene group of C3 to C10, , S ₂ is or Wherein R ₂ is an alkyl group of C3 to C5, n is an integer of from 3 to 20, and * is a bonding position in the formula (2).

In various embodiments of the invention, the cerium prepolymer has the structure of formula (3): Where V ₃ is , or , L ₃ is an alkylene group of C2 to C5, and m is an integer of 10 to 50, wherein * is a bonding position in the formula (3).

In various embodiments of the invention, the yellow dye has the structure of formula (4): Wherein R ₃ is -OH or -CH ₃ and R ₄ is -O- or -CH ₂ CH ₂ NH-.

In various embodiments of the present invention, when R ₃ of formula (4) is -OH and R ₄ is -CH ₂ CH ₂ NH-, the yellow dye has the structure of formula (5):

In various embodiments of the present invention, when R ₃ of formula (4) is -CH ₃ and R ₄ is -O-, the yellow dye has the structure of formula (6):

In various embodiments of the invention, the yellow dye has a sulfonyl group or a sulfonate group.

In various embodiments of the invention, when the yellow dye has a sulfonic acid group, the yellow dye has the structure of formula (7):

In various embodiments of the invention, the yellow dye has a sulfonate group and the sulfonate group is -SO ₃ Na, the yellow dye has the chemical structure of formula (8):

In various embodiments of the invention, the yellow dye has an amide group.

In various embodiments of the invention, when the yellow dye has a guanamine group, the yellow dye has the structure of formula (9):

In various embodiments of the present invention, the hydrophilic single system is selected from the group consisting of N-vinyl pyrrolidone (NVP), 2-hydroxyethyl methacrylate (HEMA), Glyceryl methacrylate (GM), methacrylic acid, acrylic acid, N, N-dimethyl acrylamide (DMA), N, N a group consisting of N,N-dimethyl methacrylamide and N-vinyl-N-methyl acetamide.

In various embodiments of the present invention, the crosslinking agent is selected from the group consisting of ethylene glycol dimethacrylate, diethylene glycol dimethacrylate. ), triethylene glycol dimethacrylate, tetraethylene glycol dimethacrylate, ally dimethacrylate, Ethylene glycol dially ether, triethylene glycol dially ether, tetravinyl glycol diallyl ether Tetraethylene glycol dially ether), triallyl-s-triazine-2,4,6(1H,3H,5H)-trione (triallyl-s-triazine-2,4,6(1H,3H,5H) -trione) and a group consisting of 1,1,1-trimethylolpropane trimethacrylate.

In various embodiments of the invention, the initiator is a photoinitiator.

In various embodiments of the invention, the photoinitiator is a phosphine-oxide-based initiator, a metallocene titanium compound initiator (titanium metallocene-based initiator) or a combination thereof.

In various embodiments of the present invention, the phosphine oxide initiator is selected from the group consisting of diphenyl (2,4,6-triphenyl)phosphine oxide, Bis(2,4,6-trimethylbenzoyl)phenylphosphine oxide and bis(2,6-dimethoxybenzoate) A group consisting of bis(2,4,4-trimethyllphenyl)phosphine oxide (2,4,4-trimethylpentyl) phosphine oxide.

In various embodiments of the invention, the metallocene titanium compound initiator comprises dicyclopentadienyl bis [2,4-difluoro-3] -(1-pyrrolyl)phenyl]titanium).

In various embodiments of the present invention, the water gel composition further comprises a blocking ultraviolet light monomer in an amount of 0.5 to 2 parts by weight.

In various embodiments of the invention, the blocking ultraviolet light monomer is a monomer having benzophenone, a monomer having benzotriazole, or a combination thereof.

In various embodiments of the invention, the single system having benzophenone is selected from 4-methacryloxy-2-hydroxydiphenyl ketone (4-methacryloxy-2- A group consisting of hydroxy benzophenone) and 4-(2-acryloxyethoxy-2-hydroxybenzophenone).

In various embodiments of the invention, the single system having benzotriazole is selected from the group consisting of 2-(2-hydroxy-5-methylpropenyloxyethylphenyl)-2H-benzo 2-(2-hydroxy- 5-methacryloxyethylphenyl-2H-benzotriazole), 2-(2-hydroxy-5-methylpropenyloxyethylphenyl)-2H-6-chlorobenzotriazole (2-(2-hydroxy-5-methacryloxyethylphenyl)-2H-6-chloro-benzotriazole), 2-(2-hydroxy-5-methylpropenyloxyethylphenyl)-2H-6-methoxy 2-(2-hydroxy-5-methacryloxyethylphenyl-2H-6-methoxybenzotriazole), 2-[3'- t -butyl-5'-(3"-dimethylethyldecyl-propyl Oxy)-2'-hydroxyphenyl]-5-methoxybenzotriazole (2-[3'- t- butyl-5'-(3"-dimethylvirlylsilylpropoxy)-2'-hydroxyphenyl]-5- Methoxybenzotriazole), 2-[3'- t -butyl-2'-hydroxy-5'-(3"-methylpropenylpropyl)-5-chlorobenzotriazole (2-[3'- t -butyl-5'-(3"-methacryloylozypropyl)phenyl]-5-chlorobenzotriazole) and 2-[2'-hydroxy-5'-( γ -methylpropenyloxypropoxy)-3'- t - Butylphenyl]-5-methoxy-2H-benzotriazole (2-[2'-hydroxy-5'-( γ- methacryloyl) A group consisting of oxypropoxy)-3'-tert-butylphenyl]-5-methoxy-2H-benzotriazole).

In various embodiments of the present invention, the water gel composition further comprises a hydrophobic monomer in an amount of from 1 to 10 parts by weight.

In various embodiments of the invention, the hydrophobic single system is selected from the group consisting of methyl methacrylate, butyl methacrylte, n-hexyl methacrylate, and A group consisting of isobornyl methacrylate.

In various embodiments of the present invention, the water gel composition further comprises an organic solvent, and is 1 to 30 parts by weight.

In various embodiments of the invention, the organic solvent is selected from the group consisting of A group consisting of glycerol, n-butanol, t-butanol, t-amyl alcohol, and n-hexanol.

The invention provides a water gel lens. The water gel lens comprises a lens body formed of the water gel composition of any of the above embodiments.

The features, aspects, and advantages of the present disclosure will become more apparent from the description and appended claims.

The above general description and the following detailed description are intended to be illustrative of the claimed invention.

The embodiments of the present invention are disclosed below, and for the sake of clarity, a number of practical details will be described in the following description. However, it should be understood that these practical details are not intended to limit the invention. That is, in some embodiments of the invention, these practical details are not necessary. In addition, the chemical structural formulas shown in the text will be illustrated in a simple schematic manner.

In this document, "one" and "the" can be used to mean one or more, unless the article specifically defines the article. It will be further understood that the terms "comprising", "comprising", "having", and <RTIgt; One or more of its other features, regions, integers, steps, operations, elements, components, and/or groups thereof.

Through the aforementioned problems, it can be known that the eyes are prone to cause eye diseases in the case of long-term exposure to blue light. However, the isolation of the blue light, while providing the best protection for the eye, can lead to poor vision, especially at night. Therefore, how to maintain a good visual effect while maintaining the eye, especially the night vision ability, becomes a problem that needs to be solved.

In view of the above, the present invention provides a water gel composition for preparing a water gel lens, which is made of a water gel lens which can block part of blue light to protect the eyes and has good visual effects, especially night vision ability.

The present invention provides a water gel composition for preparing a water gel lens. The hydrocolloid composition comprises a hydrophilic monomer, a blue blocking monomer, a crosslinking agent, and an initiator. Wherein the hydrophilic monomer is 30 to 60 parts by weight; the blue-blocking monomer is 0.02 to 0.5 parts by weight, and it contains a yellow dye; the crosslinking agent is 0.1 to 1 part by weight; and the initiator is 0.2 to 2 parts by weight.

In various embodiments of the invention, the hydrophilic monomer is from 96.5 to 99.68 parts by weight.

For example, the hydrophilic single system is selected from the group consisting of N-vinyl pyrrolidone (NVP), 2-hydroxyethyl methacrylate (HEMA), and glycerol methacrylate. (glyceryl methacrylate, GM), methacrylic acid, acrylic acid, N, N-dimethyl acrylamide (DMA), N, N-dimethyl A group consisting of N,N-dimethyl methacrylamide and N-vinyl-N-methyl acetamide.

In various embodiments of the present invention, the water gel composition is further included The ruthenium-containing compound is selected from the group consisting of ruthenium monomers, ruthenium polymers, and ruthenium prepolymers. When the water gel composition comprises a silicone resin, the water gel composition comprises: 5 to 59 parts by weight of a silicone compound, 30 to 60 parts by weight of a hydrophilic monomer, 0.02 to 0.5 parts by weight of a blue blocking monomer, and a crosslinking agent of 0.1. To 1 part by weight and 0.2 to 2 parts by weight of the starter.

Specifically, the silicone compound may be selected from the group consisting of a ruthenium monomer, a ruthenium high polymer, and a ruthenium prepolymer, wherein the ruthenium monomer, ruthenium high polymer, and ruthenium prepolymer may be selected from Table 1 List of various compounds:

In various embodiments of the invention, the yellow dye may be an ethylenically-based polymerizable group, a sulfonyl group, a sulfonate group or an amide group. Group) compounds, as shown in Table 2:

In various embodiments of the present invention, the crosslinking agent is selected from the group consisting of ethylene glycol dimethacrylate, diethylene glycol dimethacrylate. ), triethylene glycol dimethacrylate, tetraethylene glycol dimethacrylate, ally dimethacrylate, Ethylene glycol dially ether, triethylene glycol diallyl ether Dially ether), tetraethylene glycol dially ether, triallyl-s-triazine-2,4,6(1H,3H,5H)-trione (triallyl -s-triazine-2,4,6(1H,3H,5H)-trione) and a group consisting of 1,1,1-trimethylolpropane trimethacrylate.

In various embodiments of the invention, the initiator is a photoinitiator and the photoinitiator is a phosphine-oxide-based initiator, a titanium metallocene initiator (titanium metallocene- Based initiator) or a combination thereof.

In various embodiments of the present invention, the phosphine oxide initiator is selected from the group consisting of diphenyl (2,4,6-triphenyl)phosphine oxide, Bis(2,4,6-trimethylbenzoyl)phenylphosphine oxide and bis(2,6-dimethoxybenzoate) A group consisting of bis(2,4,4-trimethyllphenyl)phosphine oxide (2,4,4-trimethylpentyl) phosphine oxide.

In various embodiments of the invention, the metallocene titanium compound initiator comprises dicyclopentadienyl bis [2,4-difluoro-3] -(1-pyrrolyl)phenyl]titanium).

In various embodiments of the present invention, the water gel composition further comprises 0.5 to 2 parts by weight of a monomer having a benzophenone and having a benzotriazole (blocking ultraviolet monomer). Monomer of benzotriazole or a combination thereof.

In various embodiments of the invention, having diphenyl ketone The single system of (benzophenone) is selected from 4-methacryloxy-2-hydroxybenzophenone and 4-(2-acryloxyethoxy ethoxyphenone) Group consisting of 4-(2-acryloxyethoxy-2-hydroxy benzophenone).

In various embodiments of the invention, the single system having benzotriazole is selected from the group consisting of 2-(2-hydroxy-5-methylpropenyloxyethylphenyl)-2H-benzo 2-(2-hydroxy-5-methacryloxyethylphenyl-2H-benzotriazole), 2-(2-hydroxy-5-methylpropenyloxyethylphenyl)-2H-6-chlorobenzotriazole (2-(2-hydroxy-5-methacryloxyethylphenyl)-2H-6-chloro-benzotriazole), 2-(2-hydroxy-5-methylpropenyloxyethylphenyl)-2H-6-methoxy 2-(2-hydroxy-5-methacryloxyethylphenyl-2H-6-methoxybenzotriazole), 2-[3'- t -butyl-5'-(3"-dimethylethyldecyl-propyl Oxy)-2'-hydroxyphenyl]-5-methoxybenzotriazole (2-[3'- t- butyl-5'-(3"-dimethylvinylsilylpropoxy)-2'-hydroxyphenyl]-5- Methoxybenzotriazole), 2-[3'- t -butyl-2'-hydroxy-5'-(3"-methylpropenylpropyl)-5-chlorobenzotriazole (2-[3'- t -butyl-5'-(3"-methacryloylozypropyl)phenyl]-5-chlorobenzotriazole) and 2-[2'-hydroxy-5'-( γ -methylpropenyloxypropoxy)-3'- t - Butylphenyl]-5-methoxy-2H-benzotriazole (2-[2'-hydroxy-5'-( γ- methacryloylox) A group consisting of ypropoxy)-3'-tert-butylphenyl]-5-methoxy-2H-benzotriazole).

In various embodiments of the present invention, the hydrocolloid composition further comprises a hydrophobic monomer, and is 1 to 10 parts by weight, and is selected from methyl methacrylate. (methyl methacrylate), butyl methacrylte, n-hexyl methacrylate, and isobornyl methacrylate.

In various embodiments of the present invention, the water gel composition further comprises an organic solvent, and is 1 to 30 parts by weight, and is selected from the group consisting of glycerol, n-butanol, and uncle. A group consisting of t-butanol, t-amyl alcohol, and n-hexanol.

The water gel composition was placed in a pair of polypropylene molds, and subjected to a curing reaction by visible light irradiation to prepare a water gel lens, and the water gel lens was removed from the mold by dry removal. Next, after extracting with hot water, the water gel lens was placed in a polypropylene blister pack containing a boric acid saline buffer solution, sealed with an aluminum foil, and then sterilized at a high pressure at 120 ° C for 30 minutes.

The water-filled lenses made by the above manufacturing method all have a water content of 38 to 80%, preferably 40-70% of water content, and can block 10% to 55% of blue light having a wavelength of 380 to 500 nm.

The following plurality of water gel compositions are merely examples and are not intended to limit the invention. Specifically, the hydrocolloid composition 1-8 comprises: 95 parts by weight of 2-hydroxyethyl methacrylate (HEMA), 1.9 parts by weight of methacrylic acid, and vinyl glycol. 0.8 parts by weight of ethylene glycol dimethacrylate, 0.15 parts by weight of (1,1,1-trimethylolpropane trimethacrylate), oxidation of bis(2,4,6-trimethylbenzylidene)-phenylphosphine (bis(2,4,6-trimethylbenzoyl)phenyl phosphine oxide) 0.5 parts by weight of 2-(2-hydroxy-5-methylpropenyloxyethylphenyl)-2H-benzotriazole (2- (2-hydroxy-5-methacryloxyethylphenyl)-2H-benzotriazole) 1.0 parts by weight, blue dye (reactive blue 19, RB19) 0.03 parts by weight and yellow dyes of different structures and contents (as shown in Table 3). Table 3 shows the water gel lens made of water gel composition 1-8, for blue light (380 ~ 500nm) penetration:

As can be seen from Table 3, when the yellow dye in the water gel composition is 0.02-0.15 parts by weight, the blue light transmittance is 45-85%, in other words, it can block 15-55% of blue light, and in this case, The user can protect the eyes from blue light when wearing the water gel lens made of the water gel composition, and also has good visual effects, especially night vision ability.

Next, a comprehensive test of visual acuity and contract sensitivity was performed. Test the number of letters that the subject can correctly identify under different levels of illumination and contrast.

The test was performed by 30 subjects aged between 25 and 40, and the testers had a visual acuity of 20/25 when wearing their custom lenses, where "20/25" represents The target can be seen by an average person at 25 inches. The subject must be at a distance of 20 inches from the target, so the visual value is expressed as 20/25. First, the test subject is asked to wear a water-resistant plastic lens (experimental lens) made of the above-mentioned water-gel composition 7 and can block 25% of blue light, and a contact lens (control lens) which generally does not have a blue light blocking function, wherein The experimental group lens and the control lens all have the same curvature and diameter. Then, the subject is asked to identify 60 letters to be tested at different distances and contrasts (referring to the color contrast of the font and the background), and the number of letters that can be correctly recognized reflects the visual acuity and For contrast sensitivity, the results ( p value <0.05) are shown in Table 4:

From the above test results, it can be known that the experimental group lens (blocking 25% blue light) is not in the environment of sunlight, general indoor light or dim light, or high contrast, medium contrast or low contrast. Affects the ability of the subject to correctly recognize the letter. Even when compared with the control lens, the subject can correctly recognize more letters when wearing the experimental group lens, and has better visual acuity and contrast sensitivity. Even when wearing an experimental lens in a dimly lit environment, it can improve its visual acuity and contrast sensitivity.

It can be seen from the above embodiments of the present invention that the hydrocolloid lens made by the water gel composition provided by the present invention is superior to the conventional contact lens, and summarizes the advantages as follows. The water gel composition provided by the present invention is made of the same. The water gel lens blocks 10-55% of the blue light to reduce exposure of the eye to harmful blue light, thereby preventing eye diseases such as cataracts or macular diseases. At the same time, it does not affect the visual acuity and contrast sensitivity, and even allows the user to have better visual acuity and contrast sensitivity. Therefore, the user has good visual ability even under dim light.

The present invention has been described in some detail in considerable detail, but other embodiments are also possible. Therefore, the spirit and scope of the appended claims should not be limited to the embodiments described herein.

Although the present invention has been disclosed in the above embodiments, it is not intended to limit the present invention, and the present invention can be modified and modified without departing from the spirit and scope of the present invention. The scope is subject to the definition of the scope of the patent application attached.

Claims (29)

A water gel composition for preparing a water gel lens, comprising: a hydrophilic monomer, 30 to 99.68 parts by weight; a blocking blue light monomer, 0.02 to 0.5 parts by weight, and comprising a yellow dye; The crosslinking agent is 0.1 to 1 part by weight; and the initiator is 0.2 to 2 parts by weight. The hydrocolloid composition of claim 1, wherein the hydrophilic monomer is from 96.5 to 99.68 parts by weight. The water gel composition of claim 1, further comprising a gum compound selected from the group consisting of a monoterpene monomer, a monoterpene high polymer and a terpene prepolymer, and the gelatin compound is 5 to 59 parts by weight, the hydrophilic monomer is 30 to 60 parts by weight. The water gel composition of claim 3, wherein the oxime monomer has the structure of formula (1): Where V ₁ is , or , L ₁ is an alkylene group of C3~C7 or , R ₁ is methyl or Where * is the bonding position in equation (1). The water gel composition of claim 3, wherein the bismuth polymer has the structure of the formula (2): Wherein L ₂ is an alkylene group of C3 to C10, , S ₂ is or Wherein R ₂ is an alkyl group of C3 to C5, n is an integer of from 3 to 20, and * is a bonding position in the formula (2). The water gel composition of claim 3, wherein the bismuth prepolymer has the structure of formula (3): Where V ₃ is , or , L ₃ is an alkylene group of C2 to C5, and m is an integer of 10 to 50, wherein * is a bonding position in the formula (3). The water gel composition of claim 1, wherein the yellow dye has the structure of formula (4): Wherein R ₃ is -OH or -CH ₃ and R ₄ is -O- or -CH ₂ CH ₂ NH-. The water-soluble composition of claim 7, wherein R ₃ of the formula (4) is -OH, and R ₄ is -CH ₂ CH ₂ NH-, the yellow dye has the structure of the formula (5): The water gel composition of claim 7, wherein when the R ₃ of the formula (4) is -CH ₃ and R ₄ is -O-, the yellow dye has the structure of the formula (6): The hydrocolloid composition of claim 1, wherein the yellow dye has a sulfonyl group or a sulfonate group. The water gel composition of claim 10, wherein the yellow dye has the structure of the formula (7) when the yellow dye has the sulfonic acid group: The water gel composition of claim 10, wherein the yellow dye has the sulfonate group, and the sulfonate group is -SO ₃ Na, the yellow dye has the chemical structure of the formula (8): The water gel composition of claim 1, wherein the yellow dye has an amide group. The water gel composition of claim 13, wherein the yellow dye has the structure of the formula (9) when the yellow dye has the guanamine group: The water gel composition of claim 1, wherein the hydrophilic single system is selected from the group consisting of N-vinyl pyrrolidone (NVP) and 2-hydroxyethyl methacrylate (2- Hydroxyethyl methacrylate, HEMA), glyceryl methacrylate (GM), methacrylic acid, acrylic acid, N, N-dimethyl acrylamide (N, N-dimethyl acrylamide, DMA), N,N-dimethyl methacrylamide, and N-vinyl-N-methyl acetamide group. The water gel composition of claim 1, wherein the crosslinking agent is selected from the group consisting of ethylene glycol dimethacrylate, divinyl glycol dimethyl Diethylene glycol dimethacrylate, triethylene glycol dimethacrylate, tetraethylene glycol dimethacrylate, allyl methacrylic acid Allyl dimethacrylate, ethylene glycol dially ether, triethylene glycol dially ether, tetravinyl glycol Tetraethylene glycol dially ether, triallyl-s-triazine-2,4,6(1H,3H,5H)-trione (triallyl-s-triazine-2,4,6( 1H, 3H, 5H)-trione) and a group consisting of 1,1,1-trimethylolpropane trimethacrylate. The hydrocolloid composition of claim 1, wherein the initiator is a photoinitiator. The water gel composition of claim 17, wherein the photoinitiator is a phosphine-oxide-based initiator, a titanium metallocene-based initiator Or a combination thereof. The hydrocolloid composition of claim 18, wherein the phosphine oxide initiator is selected from the group consisting of diphenyl (2,4,6-triphenyl)phosphine oxide (diphenyl(2,4,6-triphenyl)phosphine oxide),bis(2,4,6-trimethylbenzylidene)-phenylphosphine oxide (bis(2,4,6-trimethylbenzoyl)phenyl phosphine Oxide) and bis(2,6-dimethoxylbenzoyl)phosphine (2,6-dimethoxylbenzoyl) (2,4,4- a group consisting of trimethylpentyl)phosphine oxide). The hydrocolloid composition of claim 18, wherein the metallocene titanium compound initiator comprises dicyclopenta[2,4-difluoro-3-(1-pyrrole)phenyl]titanium (dicyclopentadienyl bis[2] , 4-difluoro-3-(1-pyrrolyl)phenyl]titanium). The water gel composition of claim 1 further comprises a blocking ultraviolet monomer of 0.5 to 2 parts by weight. The water gel composition of claim 21, wherein the blocking ultraviolet light monomer is a monomer having benzophenone, a monomer having benzotriazole or a combination thereof. . The water gel composition of claim 22, wherein the single system having benzophenone is selected from the group consisting of 4-methylpropenyloxy-2-hydroxydiphenyl ketone ( a group consisting of 4-methacryloxy-2-hydroxy benzophenone and 4-(2-acryloxyethoxy-2-hydroxybenzophenone) . The hydrocolloid composition of claim 22, wherein the single system having benzotriazole is selected from the group consisting of 2-(2-hydroxy-5-methylpropenyloxyethylphenyl) -2H-benzotriazole (2-(2-hydroxy-5-methacryloxyethylphenyl)-2H-benzotriazole), 2-(2-hydroxy-5-methylpropenyloxyethylphenyl)-2H-6 2-(2-hydroxy-5-methacryloxyethylphenyl-2H-6-chloro-benzotriazole), 2-(2-hydroxy-5-methylpropenyloxyethylphenyl)-2H 2-(2-hydroxy-5-methacryloxyethylphenyl-2H-6-methoxybenzotriazole), 2-[3'- t -butyl-5'-(3"-dimethyl Ethylethylmercaptopropoxy)-2'-hydroxyphenyl]-5-methoxybenzotriazole (2-[3'- t- butyl-5'-(3"-dimethylvinylsilylpropoxy)-2' -hydroxyphenyl]-5-methoxybenzotriazole), 2-[3'- t -butyl-2'-hydroxy-5'-(3"-methylpropenylpropyl)-5-chlorobenzotriazole (2 -[3'- t- butyl-5'-(3"-methacryloylozypropyl)phenyl]-5-chlorobenzotriazole) and 2-[2'-hydroxy-5'-( γ -methylpropenyloxypropoxy) -3'- t -butylphenyl]-5-methoxy-2H-benzotriazole (2-[2'-hydroxy-- A group consisting of 5'-( γ -methacryloyloxypropoxy)-3'-tert-butylphenyl]-5-methoxy-2H-benzotriazole). The hydrocolloid composition of claim 1 further comprises a hydrophobic monomer in an amount of from 1 to 10 parts by weight. The water gel composition of claim 25, wherein the hydrophobic single system is selected from the group consisting of methyl methacrylate, butyl methacrylte, and n-hexyl methacrylate ( N-hexyl Methacrylate) and a group of isobornyl methacrylate. The hydrocolloid composition of claim 1 further comprises an organic solvent in an amount of from 1 to 30 parts by weight. The water gel composition of claim 27, wherein the organic solvent is selected from the group consisting of glycerol, n-butanol, t-butanol, and tert-amyl alcohol (t -amyl alcohol) and a group of n-hexanol. A water gel lens comprising: a lens body formed by the water gel composition according to any one of claims 1 to 28.