TW201711671A - Glue of tooth whitening patch which is provided with an excellent adhesion and is not easily left over when a user intends to remove it after use - Google Patents

Abstract

The present invention relates to a glue of tooth whitening patch, which comprises: 0.1-30 wt% of first thickening agent, 0.1-10 wt% of second thickening agent, 0.1-10 wt% of dihydroxyaluminum aminoacetate, 0.1-18 wt% of tooth bleaching agent, and water. With the aforementioned composition, it is able to significantly simplify the manufacturing process of tooth whitening patch, lower the expense of the manufacturing cost, and greatly increase the ionic bonding and cross-linking degree in the glue of the present invention. Accordingly, the glue of the present invention not only is provided with an excellent adhesion, but also is not easily left over when a user intends to remove it after use, thereby greatly increasing the comfort in use.

Description

Colloidal whitening patch

This creation is about a substance used for whitening teeth, especially a gel of a whitening patch.

With the rapid development of the economy, everyone's requirements for appearance are increasing, and the color of teeth is also increasingly valued. However, there are many reasons for tooth discoloration, which can be generally divided into:

1. Exogenous: staining of the tooth enamel surface. Often the surface of the teeth is browned or blackened by the patient's consumption of foods or beverages containing high pigments such as tea or coffee. In addition, smoking or chewing betel nut often causes dark brown staining of the neck of the teeth, especially on the sides of the tongue.

2. Intrinsic: changes in the color of the tooth itself, including: (1) caused by excessive fluoride; (2) caused by antibiotics (especially when teeth are formed); (3) caused by systemic diseases; (4) caused by local factors (5) caused by physiological factors; (6) discoloration caused by pulp lesions.

There are many ways to whiten your teeth, including physical whitening (whitening toothpaste planing, ultrasonic cleaning, sandblasting, etc.), chemical whitening (home whitening, cold whitening, laser whitening, etc.), as well as cover whitening (composite) Resin tooth complex whitening, dental patches, etc.). Among them, the whitening tooth paste is an elastic gel type film patch for tooth whitening, which is simple and effective, can quickly whiten the teeth; and comprises a plastic film layer, an elastic gel layer and a peeling backing layer. The plastic film layer is transparent and has a strip shape, a square shape, a circular shape, a diamond shape or a pattern of all the pattern shapes, which is suitable for the shape of the teeth of the user, and functions as a segregation saliva and protective elastic condensation. The adhesive layer comprises a peroxide as a dental bleaching agent, a plant whitening factor and a high-viscosity hydrophilic elastic gelling agent capable of forming an elastic film; the peeling backing layer is a transparent or opaque plastic sheet. The surface is coated with a stabilizer that maintains the elasticity of the gel.

Observe the current development trend of whitening toothpaste by the following patent documents that have been applied for:

1. The Republic of China Application No. 102139627, "Plastic Patch" discloses a dental patch having three layers: layer (A), layer (B) and layer (C). The layer (A) is selected from the group consisting of alkylsulfate, mercaptomethyltaurine, N-mercaptocreine, orthophosphoric acid, condensed phosphoric acid, and one or more of these salts, which are dissolved The pH value in water is between 6.6 and 10.5; the layer (B) is selected from the group consisting of phytic acid, hexametaphosphoric acid, an organic acid having a pKa value of 4.5 to 7.0 at 25 ° C, and one or two of the salts. The above components are dissolved in water at a pH between 3.5 and 6.5; the layer (C) is selected from the group consisting of cellulose acetate phthalate, polyvinyl acetate, ethyl cellulose, and polymethyl methacrylate. And one or more (co)polymers of methacryloyl thioethyl betaine-methacrylate copolymer, methacrylic acid copolymer and aminoalkyl methacrylate copolymer. Wherein the component of layer (A) is coated on a polyethylene terephthalate (PET) film and allowed to dry, and the component of layer (B) is applied to layer (A) and allowed to dry. After that, the PET film is replaced with a layer (C), and the dental patch can be prepared. The sequential lamination and the process of replacing the PET film with the layer (C) are quite costly and labor intensive.

2. ROC Application No. 101141076 "dental film formulation" discloses a dental film formulation, which formulation consists essentially of dental film acrylates / octyl acrylamide copolymer (Dermacryl ^® 79), ethylcellulose (Ethocel ^® E50), hydroxypropyl cellulose and ethanol, optionally further containing whitening materials (titanium dioxide, zinc oxide, hydroxyapatite and combinations thereof), antibacterial agents, fluoride ion sources, calcium sources, alkaline Amino acid, or other active agent. A drawback of this invention as follows: (1) acrylates / octyl acrylamide copolymer (Dermacryl ^® 79) it is expensive; (2) the film formulation based tooth whitening teeth belonging to the physical embodiment, through formulation The whitening ingredient/active agent is delivered to the surface of the tooth and coated to protect the tooth from the transmission system of plaque and biofilm formation; however, this method is easy to cause the tooth due to different personal eating habits and maintenance methods. The film formulation disintegrates and does not adequately perform the desired effect to protect or coat the tooth surface.

3. The Republic of China Application No. 094145567 "Condiment and System for Slow-Release Teeth Whitening" discloses a blend of sustained-release teeth whitening. The inner layer of the tooth whitening agent of the blend is composed of Eudragit ^® RL PO (38 wt%). ) or Eudragit ^® E PO (38.00 wt%), Eudragit ^® L 100–55 (3.79 wt%), triethyl citrate (20.31 wt%), Kollidon ^® CL–M (15.00 wt%), sodium percarbonate ( 17.63 wt%) and carbamide peroxide (5.28 wt%), prepared by melt-kneading; the outer layer of the tooth whitening agent of the blend is composed of Eudragit ^® RS PO (72.06 wt%) and triethyl citrate (20.31 wt %), sodium percarbonate (5.88 wt%) and urea peroxide (1.76 wt%), prepared by melt-kneading. The preparation method is summarized as follows: after the inner layer blend is coated on a polyethylene terephthalate (PET) film and high-pressure flattened, the outer layer blend is applied to the inner layer blend and high-pressure flattened. The PET film is then replaced with a non-woven material layer (Polyamide, PA), and then the non-woven material layer is attached to the PET film and high-pressure flattened to prepare a blend of the sustained-release tooth whitening.

4. The Republic of China Application No. 092137728 "Dry Patch for Whitening Teeth" invents a dry patch for whitening teeth. The patch has three layers: an adhesive layer, an active material adhesive layer and a backing layer. By way of example, the first example is as follows: the adhesive layer is composed of hydroxypropyl cellulose (30 wt%) and ethanol (70 wt%); the active material adhesive layer is composed of polyvinyl alcohol (10 wt%), polyvinylpyrrolidone (10 wt%), sodium pyrophosphate peroxide (5 wt%), alkyl aryl sulfonate (2 wt%) and water (78 wt%); backing layer from ethyl cellulose (8 It consists of wt%), Eudragit (5 wt%), castor oil (4 wt%) and ethanol (83 wt%). The preparation process is also carried out by sequential lamination, and will not be further described herein.

According to the above-mentioned patent documents, although the patch glue of the prior art has sufficient adhesion, the process is very cumbersome and time-consuming (in the manner of sequential lamination), and costs are high in personnel and equipment, and When the colloid is used, it is easy to disintegrate. After many consumers use it, when the patch is removed from the surface of the tooth, many of the patch's colloids often remain. The residue of the colloid cannot be completely removed through the mouthwash, and even the brushing can be completely completed. Clear, causing great discomfort to consumers. Therefore, the creator believes that the colloid of the conventional tooth whitening patch should have an improved way.

In view of the deficiencies of the prior art, the creator of the present invention has created a colloid of a tooth whitening patch, including:

0.1 to 30 wt% of a first thickener selected from the group consisting of sodium carboxymethyl cellulose (CMC-Na), methyl cellulose (MC), and hydroxy Hydroxyethyl cellulose (HEC), hydroxypropyl cellulose (HPC), hydroxypropyl methyl cellulose (HPMC), microcrystalline cellulose, modified starch Modified starch) and a group of sodium polyacrylates;

0.1 to 10 wt% of a second thickener selected from the group consisting of methyl vinyl ether-maleic anhydride copolymer, vinyl pyrrolidone-vinyl acetate copolymer, polyethylene oxide-polyoxidation Propylene block copolymer (Poloxamer 407), polyvinyl alcohol (PVA), polyvinyl pyrrolidone (PVP), polyacrylic acid (PAA), cross-linked polyacrylic resin (Carbomer or Carbopol), a group consisting of Polyquaternium-11 (Polyquaterium-11) and Polyquaternium-39 (Polyquaterium-39);

0.1 to 10 wt% of dihydroxyaluminum aminoacetate;

0.1~18 wt% dental bleach;

The rest is water and the sum is 100 wt%.

With the above arrangement, the present invention only needs to sequentially add the first thickener, the second thickener, the cross-linking agent and the water and stir evenly to obtain the colloid of the present invention, and the general coating can be subsequently used. In this way, a tooth whitening patch is prepared without the need for sequential lamination as in the prior art, which greatly simplifies the manufacturing process of the tooth whitening patch and reduces the cost of manufacturing. Moreover, the combination of the first and second thickeners and the aluminum hydride aluminum acetate can greatly increase the degree of ionic bonding and cross-linking in the present colloid, so that the colloid of the present invention not only has good adhesion. It also makes it easier for users to remove after use, and greatly increases the comfort during use.

(1) ‧‧‧SMD ontology

(10) ‧‧‧lateral indentation

(11)‧‧‧Cone gap

The first figure is an appearance of an embodiment of a tooth whitening patch made of the colloid of the present invention.

The construction, features and embodiments of the present invention will be described with the aid of the drawings, and the reviewers will have a better understanding of the present invention.

This creation is about the colloid of a tooth whitening patch. A tooth whitening patch is a patch that can be adhered to and wrapped around a tooth and removes the dentate pigment to increase its whiteness. The colloid disposed between the backing layer and the release layer of the tooth whitening patch can be adhered to the tooth and directly contact the tooth surface. The colloid includes:

0.1~30 wt% of the first thickener: sodium carboxymethyl cellulose (CMC-Na), methyl cellulose (MC), hydroxyethyl cellulose (hydroxyethyl cellulose, HEC), hydroxypropyl cellulose (HPC), hydroxypropyl methyl cellulose (HPMC), microcrystalline cellulose, modified starch or sodium polyacrylate ( Sodium polyacrylate). By the composition of the first thickener described above, the degree of ionic bonding in the colloid of the present invention can be increased, and the structural stability of the colloid can be enhanced.

0.1 ~ 10 wt% of secondary thickener: may be methyl vinyl ether - maleic anhydride copolymer ^{(Gantrez TM AN-119, Gantrez} TM AN-139, Gantrez ® S-97 BF), vinyl pyrrolidone - Vinyl acetate copolymer (Luviskol ^® VA Grades, Plasdone ^® S-630 Copovidone), polyethylene oxide-polyoxypropylene block copolymer (Poloxamer 407, Pluronic ^® F-127), polyvinyl alcohol (PVA) , polyvinyl pyrrolidone (PVP), polyacrylic acid (PAA), cross-linked polyacrylic resin (Carbomer or Carbopol), polyquaternium-11 (Polyquaterium-11 or Gafquat ^® 755N) or polyquaternium salts ^{-39 (Polyquaterium-39 or Merquat TM} Plus 3330). By the second thickener, the degree of hydrogen bonding and ionic bonding in the colloid of the present invention can be increased, and the structural stability of the colloid can be reinforced.

0.1 to 10 wt% of dihydroxyaluminum aminoacetate: as a cross-linking agent of the present colloid, to increase the degree of cross-linking in the colloid of the present invention, and to reduce colloidal disintegration.

0.1~18 wt% dental bleach: the dental bleach can be hydrogen peroxide (H ₂ O ₂ ), carbamide peroxide (CH ₄ N ₂ O·H ₂ O ₂ ), peroxidation Calcium peroxide (CaO ₂ ), sodium percarbonate (2Na ₂ CO ₃ •3H ₂ O ₂ ), sodium perborate (NaBO ₃ · 4H ₂ O) or tetrasodium peroxyphosphate One or more of pyrophosphate peroxide, Na ₄ O ₈ P ₂ ). The dental bleaching agent can achieve the effect of removing the dentate pigment and whitening the teeth.

With the above arrangement, the present invention only needs to sequentially add the first thickener (sodium polyacrylate), the second thickener (polyacrylic acid), the crosslinking agent (aluminum hydride acetate) and water and stir evenly. After that, the colloid of the present invention can be obtained, and the tooth whitening patch can be prepared by the general coating method without the need of the sequential lamination method as in the prior art, and the tooth whitening patch is greatly simplified. Manufacturing process and reduce the cost of manufacturing costs.

Moreover, the combination of the first and second thickeners and the aluminum hydride aluminum acetate can greatly increase the degree of ionic bonding and cross-linking in the present colloid, so that the colloid of the present invention not only has good adhesion. It also makes it easier for users to remove after use, and greatly increases the comfort during use. Moreover, the adhesion and release properties of the colloid can be adjusted by the ratio of the first and second thickeners and the aluminum hydride acetate.

In a preferred embodiment, the colloid further comprises 0.1 to 1 wt% of a coloring agent, and the coloring agent may be New Coccine (red 6 (0.5) - KIRIYA or red 6 (1) - MAP ), Erythrosine (Red No. 7 (0.5) – KIRIYA or Red No. 7 (1) – MAP), Allura Red AC (Red Forty (1) – MAP), Lemon Yellow (Tartrazine) (yellow) 4 (0.5) – KIRIYA or Yellow 4 (1) – MAP), Sunset Yellow FCF (Yellow 5 (0.5) – KIRIYA or Yellow 5 (1) – MAP) or Brilliant Blue (Brilliant Blue) FCF) (Blue One (1) – MAP). The color of the present gel is imparted by the toner to increase the aesthetic appearance. (The pigment number described in this manual is based on the “Scope of Use and Limits and Specifications of Food Additives” promulgated by the Ministry of Health and Welfare of the Republic of China.)

In a preferred embodiment, the colloid further comprises 0.1 to 1 wt% of a flavor enhancer, and the flavor enhancer may be stevioside, sorbitol, mannitol, maltitol, xylitol, glycyrrhizin, and hay leaves. , sodium cyclamate, banana flavor, grape flavor, cocoa flavor, pineapple flavor, orange flavor, peach flavor, apple flavor, mint flavor, green mint flavor, strawberry flavor, fennel, vanillin, lemon flavor, Cherry flavor, rose essence, corn syrup, galactose, lactose, maltose, corn syrup transformed with enzyme, glucose, sucrose, fructose, cyclohexyl sulfonamide, aspartame, potassium sulfonate, Stevioside, mangosteen, saccharin, sucralose, 5-nitro-2-propoxyaniline or neotame (including corn syrup, galactose, lactose, maltose, sorbitol, corn syrup transformed with enzyme, glucose, maltitol) , sucrose, xylitol, fructose, cyclohexyl (hydro) sulfanilic acid, aspartame, potassium sulfamate, stevioside, mangosteen, saccharin, sucralose, 5-nitro-2-propoxy Aniline and nucleus As a sweetener). Through the odorant, the odor or sweet taste of the created gel is increased, and the user's sense of smell or taste is increased, and the bitter taste sensation is modified or reduced. .

In a preferred embodiment, the colloid further comprises 0.1 to 10 wt% of a peroxide stabilizer, and the peroxide stabilizer may be an alkyl sulfonate or an alkyl sulphate. Alkyl carboxylates, alkyldiphenyloxide disulphonates, a series of stear, such as sorbitan monolaurate (Span 20), sorbitol Sodium palmitate (sorbitan monpalmitate, Span 40), sorbitan monostearate (Span 60), sorbitan monooleate (Span 80), sorbitan trioleate, Span 85) or Tween emulsifier series (POE sorbitan fatty acid ester series). The peroxide stabilizer can increase the coating effect of the peroxide in the colloid of the present invention, and stabilize the peroxide from being volatile or lost.

In a preferred embodiment, the hydrophilic colloid further comprises a transparent polymer of 0.1 ~ 30 wt%, the hydrophilic polymer may be a transparent methyl vinyl ether - maleic anhydride copolymer (Gantrez ^TM AN-119, Gantrez ^TM AN-139, Gantrez ^® S-97 BF), Vinylpyrrolidone-Vinyl Acetate Copolymer (Luviskol ^® VA Grades, Plasdone ^® S-630 Copovidone), Polyethylene Oxide - Polyoxypropylene Block Copolymer (Poloxamer) 407, Pluronic ^® F-127), polyvinyl alcohol (PVA / EG-03P ~ EG-48P), polyvinyl pyrrolidone (PVP / K-15 ~ K-90), polyacrylic acid , PAA), crosslinked polyacrylic acid resin (Carbomer or Carbopol), Polyquaternium ^{-11 (Polyquaterium-11 or Gafquat ®} 755N) or Polyquaternium ^{-39 (Polyquaterium-39 or Merquat TM} Plus 3330), and the The composition of the hydrophilic transparent polymer is different from the second thickener. The hydrophilic transparent polymer can increase the peroxide coating effect in the colloid of the present invention, stabilize the peroxide from being volatilized or lost, and control the release rate of the peroxide.

In a preferred embodiment, the colloid further comprises 0.1 to 1 wt% of a bacteriostatic agent, and the bacteriostatic agent may be methyl paraben (MP) or propyl paraben (propyl paraben). , PP). The bacteriostatic agent can increase the antibacterial effect of the created colloid, slow down the variation of its quality, and prolong its shelf life.

In a preferred embodiment, the colloid further comprises 0.1 to 5 wt% of a third thickener, and the third thickener may be sodium carboxymethyl cellulose (CMC-Na), methyl. Methyl cellulose (MC), hydroxyethyl cellulose (HEC), hydroxypropyl cellulose (HPC), hydroxypropyl methyl cellulose (HPMC), microcrystalline Microcrystalline cellulose, modified starch or sodium polyacrylate, and the composition of the third thickener is different from the first thickener. The third thickener can increase the consistency of the present colloid, avoiding insufficient colloidal consistency and being unable to coat.

In a preferred embodiment, the colloid further comprises 0.1 to 50 wt% of a dispersant, and the dispersant may be glycerin, propylene glycol (PG), polyethylene glycol 200 (PEG). 200), polyethylene glycol 300 (PEG 300) or polyethylene glycol 400 (PEG 400). The dispersing agent can increase the dispersibility of the powder during the preparation process of the gel, in order to avoid the possibility of uneven dispersion during the mixing process of the colloid.

In a preferred embodiment, the colloid further comprises 0.1 to 5 wt% of an auxiliary agent, which may be hydrochloric acid, acetic acid, citric acid, methanesulfonic acid, lactic acid, tartaric acid, fumaric acid or malic acid (above It is a pharmaceutically acceptable acidulating agent; sodium hydroxide, potassium hydroxide, meglumine, tromethamine, sodium hydrogencarbonate, monoethanolamine, diethanolamine or triethanolamine (the above is a pharmaceutically acceptable alkalizing agent). The additive can impart the acidity and alkalinity of the present colloid, thereby promoting the degree of colloid crosslinking.

The following is a description of the proportions of the various embodiments of the colloids of the present invention, and the manner in which they can be prepared:

Table 1 is a list of the proportions of the components of the colloid of the present invention, which can be obtained by:

1. Add 0.1 wt% erythrosine (red No. 7), 0.2 wt% vanillin, 0.1 wt% maltitol, 10.0 wt% sorbitol monopalmitate and 3.0 wt% cross-linked polyacrylic resin to an appropriate amount of sterile water. , ultrasonic vibration is performed to form solution A.

2. 0.2 wt% methylparaben, 0.2 wt% propylparaben, 1.0 wt% aluminum hydride acetate, 5.0 wt% sodium carboxymethylcellulose, 5.0 wt% polyquaternium- 39, 2.5 wt% modified starch and 40.0 wt% glycerol / propylene glycol, mixed evenly, poured into the solution A, and added an appropriate amount of sterile water and stirred to form a solution B.

3. Add 1.2 wt% methanesulfonic acid to an appropriate amount of sterile water, mix well and pour into solution B to form solution C.

4. Add 5.0 wt% polyvinylpyrrolidone and 5.0 wt% sodium perborate to an appropriate amount of sterile water, mix well, pour into solution C and mix well to obtain a colloid of the above composition ratio.

Table 2 is a list of component proportions of another specific embodiment of the colloid of the present invention, which can be obtained by:

1. Add 0.1 wt% lemon yellow and bright blue, 0.1 wt% mint flavor, 0.1 wt% aspartame, 8.0 wt% sorbitol monooleate and 1.5 wt% cross-linked polyacrylic resin to an appropriate amount of sterile water for super The sound wave oscillates to form solution A.

2. 0.2 wt% methylparaben, 0.3 wt% propylparaben, 1.0 wt% aluminum hydride acetate, 8.0 wt% hydroxypropyl methylcellulose, 4.0 wt% polyquaternium -11, 2.5 wt% modified starch and 35.0 wt% propylene glycol, after mixing evenly, pour the solution A and add appropriate amount of sterile water, and stir to form solution B.

3. Add 1.2 wt% citric acid to an appropriate amount of sterile water, mix well and pour into solution B to form solution C.

4. Add 7.5 wt% polyvinylpyrrolidone and 6.0 wt% carbamide peroxide to an appropriate amount of sterile water, mix well, pour into solution C and mix well to obtain a colloid of the above composition ratio.

Table 3 is a list of the proportions of the components of the colloid of the present invention, which can be obtained by the following methods:

1. Add 0.1 wt% bright blue (blue No. 1), 0.1 wt% spearmint flavor, 0.1 wt% stevioside, 10.0 wt% sorbitol, and 1.0 wt% polyvinyl alcohol EG-40P to an appropriate amount of sterile water. The ultrasonic wave oscillates to form solution A.

2. 0.2 wt% methylparaben, 0.1 wt% propylparaben, 1.0 wt% aluminum hydride acetate, 8.0 wt% sodium polyacrylate, 5.0 wt% polyacrylic acid, 0.5 wt% carboxymethyl After the cellulose sodium and 35.0 wt% glycerin are uniformly mixed, the solution A is poured and an appropriate amount of sterile water is added, and then stirred to form a solution B.

3. Add 1.5 wt% tartaric acid to an appropriate amount of sterile water, mix well and pour into solution B to form solution C.

4. Add 3.0 wt% polyvinylpyrrolidone and 6.0 wt% hydrogen peroxide to an appropriate amount of sterile water, mix well, pour into solution C and mix well to obtain a colloid of the above composition ratio.

In addition, referring to the first figure, the tooth whitening patch made of the colloid of the present invention can be implemented as follows:

It has a patch body (1) that can be used for palate or mandible teeth depending on its size and contour. The patch body (1) has a wave shape on the upper and lower edges. The middle portion of the patch body (1) has a bendable lateral indentation (10) for folding the patch body (1) inwardly while covering the inside and the outside of the tooth.

The patch body has a tapered notch (11) for completely covering the inside of the tooth. The patch body (1) has a wider portion for attaching to the outside of the tooth, and a portion for attaching to the inner side of the tooth is narrower for smoothly fixing the inside and the outside of the eight teeth.

The patch body (1) is preferably used in a width and shape to maintain a minimum contact area with the gums to avoid or reduce irritation to the gums and to provide an excellent wear resistance.

In summary, the creation of the present invention is indeed in line with the industrial applicability, and is not found in the publication or public use before the application, nor is it known to the public, and has non-obvious knowledge, conforms to the patentable requirements, and is patented according to law. Application.

However, the above-mentioned statements are a preferred embodiment of the invention in the creation of the invention, and all the changes in the scope of the patent application according to the invention are within the scope of the claim.

(1) ‧‧‧SMD ontology

(10) ‧‧‧lateral indentation

(11)‧‧‧Cone gap

Claims (10)

A colloid for a tooth whitening patch comprising:
0.1 to 30 wt% of a first thickener selected from the group consisting of sodium carboxymethyl cellulose (CMC-Na), methyl cellulose (MC), and hydroxy Hydroxyethyl cellulose (HEC), hydroxypropyl cellulose (HPC), hydroxypropyl methyl cellulose (HPMC), microcrystalline cellulose, modified starch Modified starch) and one of the groups consisting of sodium polyacrylate;
0.1 to 10 wt% of a second thickener selected from the group consisting of methyl vinyl ether-maleic anhydride copolymer, vinyl pyrrolidone-vinyl acetate copolymer, polyethylene oxide-polyoxidation Propylene block copolymer (Poloxamer 407), polyvinyl alcohol (PVA), polyvinyl pyrrolidone (PVP), polyacrylic acid (PAA), cross-linked polyacrylic resin (Carbomer or Carbopol), One of the groups consisting of Polyquaternium-11 (Polyquaterium-11) and Polyquaternium-39 (Polyquaterium-39);
0.1 to 10 wt% of dihydroxyaluminum aminoacetate;
0.1~18 wt% dental bleaching agent to remove dentate pigment and whiten teeth;
The rest is water and the sum is 100 wt%. The colloid of the tooth whitening patch according to claim 1, wherein the colloid further comprises 0.1 to 30 wt% of a hydrophilic transparent polymer selected from the group consisting of methyl vinyl ether. - Maleic anhydride copolymer, vinyl pyrrolidone - vinyl acetate copolymer, polyethylene oxide - polyoxypropylene block copolymer (Poloxamer 407), polyvinyl alcohol (PVA), polyvinyl pyrrolidone (polyvinyl pyrrolidone, PVP), polyacrylic acid (PAA), cross-linked polyacrylic resin (Carbomer or Carbopol), polyquaternium-11 (Polyquaterium-11) and polyquaternium-39 (Polyquaterium-39) One of the groups, and the component of the hydrophilic transparent polymer is different from the second thickener. The colloid of the tooth whitening patch according to claim 1, wherein the colloid further comprises 0.1 to 5 wt% of a third thickener, and the third thickener is selected from the group consisting of carboxymethyl cellulose. Sodium carboxymethyl cellulose (CMC-Na), methyl cellulose (MC), hydroxyethyl cellulose (HEC), hydroxypropyl cellulose (HPC), hydroxypropyl group One of a group consisting of hydroxypropyl methyl cellulose (HPMC), microcrystalline cellulose, modified starch, and sodium polyacrylate, and the third thickener The ingredients are different from the first thickener. The colloid of a tooth whitening patch according to any one of claims 1 to 4, wherein the dental bleaching agent is selected from the group consisting of hydrogen peroxide (H ₂ O ₂ ), carbamide peroxide (carbamide peroxide, CH ₄ N ₂ O·H ₂ O ₂ ), calcium peroxide (CaO ₂ ), sodium percarbonate (2Na ₂ CO ₃ •3H ₂ O ₂ ), sodium perborate (sodium) Perborate, NaBO ₃ · 4H ₂ O) and one of the groups consisting of tetrasodium pyrophosphate peroxide (Na ₄ O ₈ P ₂ ). The colloid of a tooth whitening patch according to claim 5, wherein the colloid further comprises 0.1 to 10 wt% of a peroxide stabilizer selected from the group consisting of alkyl sulfonates. (alkylaryl sulphonates), alkyl sulphates, alkyl carboxylates, alkyldiphenyloxide disulphonates, a series of hard sorbitan (Span), such as sorbitol Lauric acid ester (sorbitan monolaurate, Span 20), sorbitan monpalmitate (Span 40), sorbitan monostearate (Span 60), sorbitan monooleate (sorbitan monooleate, Span 80), one of the group consisting of sorbitan trioleate (Span 85) and the Tween emulsifiitan fatty acid ester series. The colloid of a tooth whitening patch according to any one of claims 1 to 4, wherein the colloid further comprises 0.1 to 1 wt% of a coloring agent selected from the group consisting of carmine (New Coccine), Erythrosine, Allura Red AC, Tartrazine, Sunset Yellow FCF, and Brilliant Blue FCF. The colloid of a tooth whitening patch according to any one of claims 1 to 4, wherein the colloid further comprises 0.1 to 1 wt% of a flavoring agent, the flavoring agent being selected from the group consisting of stevia , sorbitol, mannitol, maltitol, xylitol, glycyrrhizin, hay leaf, sodium cyclamate, banana flavor, grape flavor, cocoa flavor, pineapple flavor, sweet orange flavor, peach flavor, apple Fragrance, Mint Flavor, Spearmint, Strawberry Flavor, Fennel, Vanillin, Lemon Flavor, Cherry Flavor, Rose Flavor, Corn Syrup, Galactose, Lactose, Maltose, Enzyme-Converted Corn Syrup, Glucose, Sucrose, Fructose, Ring a group consisting of hexyl sulfonamide, aspartame, acesulfame potassium, stevioside, mangosteen, saccharin, sucralose, 5-nitro-2-propoxyaniline and neotame One. The colloid of a tooth whitening patch according to any one of claims 1 to 4, wherein the colloid further comprises 0.1 to 1 wt% of a bacteriostatic agent, and the bacteriostatic agent is a paraben Ester (methyl paraben, MP) or propyl paraben (PP). The colloid of a tooth whitening patch according to any one of claims 1 to 4, wherein the colloid further comprises 0.1 to 50 wt% of a dispersing agent selected from glycerin. One of a group consisting of propylene glycol (PG), polyethylene glycol 200 (PEG 200), polyethylene glycol 300 (PEG 300) and polyethylene glycol 400 (PEG 400). The colloid of the tooth whitening patch according to any one of claims 1 to 4, wherein the colloid further comprises 0.1 to 5 wt% of an auxiliary agent selected from the group consisting of hydrochloric acid and acetic acid. Composition of citric acid, methanesulfonic acid, lactic acid, tartaric acid, fumaric acid, malic acid, sodium hydroxide, potassium hydroxide, meglumine, tromethamine, sodium hydrogencarbonate, monoethanolamine, diethanolamine and triethanolamine One of the groups.