TW201626992A - Facial mask formulation - Google Patents

Abstract

This invention relates to a facial mask formulation for manufacturing a kind of facial mask used for the recovery treatment course after facial cosmetic surgery, comprising 0.0001-0.001wt% of platonin, 3-15wt% of propylene glycol, 3-15wt% of butylene glycol, 1-10wt% of thickener, 0.5-5wt% of bacteriostatic agent, and using water to complement the part less than 100wt%. This ingredient proportion enables the facial mask formulation to effectively accelerate postoperative wound healing and reduce inflammatory response, so as to enable the patient to perform self-postoperative recovery care.

Description

Mask material

This creation is about a skin care product, especially a masking agent.

The global medical beauty industry is prevalent. From the early medical aesthetic surgery to the popular treatments of micro-plastic, small-needle beauty and laser rejuvenation, the trend of the medical beauty industry has moved toward the stage of miniaturization and home-based treatment. Whether the treatment effect can be extended and maintained efficiently is the key to the success of the medical treatment.

After non-invasive medical treatment, the skin will have a burning and tingling sensation. At this time, the skin is in an "acute inflammatory phase"; after the invasive medical treatment, the skin will produce wounds, redness, heat and other inflammatory reactions. It is a must after the art. The extent and duration of wound healing is closely related to the care and care of the subject. It is generally believed that the recovery of postoperative skin needs to grasp the so-called "72 hours after surgery" recovery period, especially in medical cosmetic surgery, where the skin is more fragile and delicate, so the postoperative recovery period is used in the face. Is the core of the entire postoperative course.

Most of the facial skin care depends on the mask. However, the mask on the market is obviously insufficient for the repair of red and swollen wounds after surgery. Some of them are even irritating. In severe cases, the fragile skin condition will be aggravated, for example, due to wound infection. Complications such as cellulitis and ulceration. Therefore, the creator believes that it is necessary to develop a repairing masking agent that can be used for postoperative recovery of medical and beauty treatments to help the subject recover the red, swollen and inflamed facial skin.

In view of the shortcomings of the prior art, the present author created a masking agent for making a mask that can be used for restorative treatment after facial cosmetic surgery, including:

0.0001-0.001% by weight of Platonin,

3-15% by weight of Propylene Glycol,

3-15 wt% Butylene Glycol,

1-10% by weight thickener,

And 0.5-5 wt% of a bacteriostatic agent,

The rest is water and the total is 100%.

By adding Platonin to the masking agent, together with the moisturizing ability of the Propylene Glycol and Butylene Glycol, the Platonin together with the moisture and Other nutrients are applied to the skin surface for a long time, so that the skin can fully absorb the Platonin. The ratio of the ingredients enables the masking agent to effectively accelerate post-operative wound healing and reduce the inflammatory response, and allows the subject to perform postoperative recovery care.

The first picture is the erythema value bar graph of the recipient before and after receiving the microneedle surgery for 15 minutes after applying the mask material of the present invention.

The construction, features and embodiments of the present invention will be described with the aid of the drawings, and the reviewers will have a better understanding of the present invention.

This creation is about a masking agent that can be used as a mask for post-cosmetic surgery. It can be used in the recovery period after facial cosmetic surgery to help the injured person recover from inflamed and red skin. .

The main components of the masking agent of this creation are described below:

Platonin:

It accounts for 0.0001-0.001% by weight of the total. Platonin is a therapeutic agent that promotes wound healing, anti-sickness, tissue activation, and cell regeneration, which accelerates wound scarring and reduces the risk of bacterial infection. In clinical trials, Platonin can help all kinds of wounds (such as fire, heat, frostbite, cut, lower leg ulcers, etc.) wound healing, improve inflammation, inhibit endotoxin, inhibit free radicals and treat sepsis Wait. According to the clinical trials of Ma Rong Hospital, Platonin can prolong the survival rate of skin grafts.

Therefore, the addition of Platonin to the mask of this creation can help reduce the inflammation and redness of the wound after micro plastic surgery, and accelerate wound scarring and cell metabolism to effectively help the subject to recover from postoperative inflammation. Facial skin.

Placenta:

It accounts for 0.01-50% by weight of total amount. Placenta is an extract from healthy placenta. Placenta has the functions of promoting blood circulation, tissue regeneration, helping cells to regenerate, improving skin metabolism, and effectively preventing melanin. precipitation.

Glutathione:

Glutathione is an important antioxidant in the body, and it has functions such as scavenging free radicals and detoxification in clinical experiments.

Propylene Glycol and Butylene Glycol:

3-15wt% and 3-15wt% of the total, respectively, Propylene Glycol and Butylene Glycol are water-soluble polyols, which can help dissolve water-insoluble substances. In water, and because of its ability to form a film on the surface of the skin, it has a moisturizing effect and is commonly used in facial masks or other moisturizing cosmetics.

In this creation, Propylene Glycol and Butylene Glycol can help to dissolve the Platonin, Placenta, Glutathione or other nutrients. The co-solvent also forms a film on the surface of the skin, which dissolves and coats the Platonin, Placenta, Glutathione and other nutrients on the skin surface. The ingredients such as Platonin can adhere to the surface of the skin with moisture for a long time, so that Platonin can exert its maximum effect.

Thickener:

It accounts for 1-10% by weight of the total, preferably using trehalose. Trehalose is a natural sugar that increases the viscosity of the masking agent to make the masking agent easier to adhere to the skin and has a moisturizing effect.

In addition to trehalose, it is preferred to add 0.05 to 3% by weight of Hydroxyethyl Cellulose and 0.05 to 3% by weight of Xanthan Gum. Hydroxyethyl Cellulose is a hydrophilic thickener that can be adjusted to increase the viscosity of the masking agent. Xanthan Gum is a vegetable thickener that also increases the consistency of the masking agent.

Bacteriostatic agent:

From 0.5 to 5% by weight of the total amount, preferably 1,2-pentanediol (Pentylene Glycol). 1,2-pentanediol (Pentylene Glycol) not only inhibits the growth of microorganisms, but also mild and does not irritate the skin, making the mask of this creation more suitable for use in inflamed and swollen skin after facial surgery.

In addition, 0.001-3% by weight of Glyceryl Caprylate, 0.001-3% by weight of Ethylhexylglycerin, 0.001-3% by weight of Caprylyl Glycol, and 0.001-3% by weight may be added. A bacteriostatic agent such as Dipropylene Glycol to extend the shelf life of the masking agent of the present invention.

In addition to the above ingredients, the masking agent of the present invention is preferably added:

Lactobacillus Ferment: 0.5 to 5 wt% of the total amount, which can increase the moisturizing effect of the masking agent of the present invention.

Avena Sativa Kernel Extract: 0.011-3% by weight of the total, which is an active ingredient with anti-allergic effects.

Sodium Hyaluronate: 0.01-0.1% by weight of the total amount, which is an active ingredient, which can increase the moisturizing effect of the masking agent of the present invention.

EGF growth factor (Oligopeptide-1): 0.001-0.1wt% of the total amount,

The following is a composition ratio of a preferred embodiment of the masking agent of the present invention:

Platonin: 0.001wt%

Placenta: 0.010wt%

Glutathione: 0.010wt%

Propylene Glycol: 7.500wt%

Butylene Glycol: 7.500wt%

Trehalose: 3.000wt%

Hydroxyethyl Cellulose: 0.200wt%

Xanthan Gum: 0.100wt%

1,2-pentanediol (Pentylene Glycol): 1.000 wt%

Glyceryl Caprylate: 0.0001% by weight

Ethylhexylglycerin: 0.0001% by weight

Caprylyl Glycol: 0.0001% by weight

Dipropylene Glycol: 0.0001% by weight

Lactobacillus Ferment: 3.000wt%

Avena Sativa Kernel Extract: 0.500wt%

Sodium Hyaluronate: 0.030wt%

Egf growth factor (Oligopeptide-1): 0.010wt%

Yeast Ferment Extract: 0.001% by weight

Water: 77.1386wt%

Although Platonin is commonly used in general medical treatment for severe wound wounds and inflammation, the administration of Platonin is mostly via injection and cannot be specifically applied to the facial skin. Even if it is applied as a general external medicine, it will not leave the effect on the skin for a long time. In this work, by adding Platonin to the masking agent, the propylene glycol (Propylene Glycol) and Butylene Glycol (Butylene Glycol) can further moisturize the Platonin together with water and Other nutrients are applied to the skin surface for a long time, so that the skin can fully absorb the effect of Platonin. This setting allows the masking agent to accelerate post-operative wound healing, reduce inflammatory response, and allows the subject to perform postoperative recovery care.

The masking agent of the present invention is preferably applied to a mask body made of biofiber, which is commonly used as an artificial skin and a material for assisting blood vessel repair. The biofiber has a diameter of about 2-100 nm, which can form a close fit with the fine grooves on the surface of the human skin, so as to greatly increase the total area of the skin material absorbed by the skin, so that the postoperative recovery effect is better.

The following test explores the practical effects of applying this facial mask to the face after cosmetic surgery to help restore inflammation and redness. The erythema value of the face after applying the facial masking agent for 15 minutes before and after the face microneedle surgery was tested. The erythema is caused by the skin's irritation and causes an immune reaction, which causes skin irritation and inflammation. Therefore, the erythema value can be used as an indicator of the degree of skin inflammation. The erythema value is used to make a face screenshot using Totally Derma (TD, a multi-functional skin analyzer), and its special software can analyze and count the erythema to obtain a erythema value.

Please refer to the first figure. The strips from left to right show the erythema value of the normal skin before the microneedle surgery, the erythema value of the inflamed skin after microneedle surgery, and the mask applied to the creation. The skin erythema value after 15 minutes. According to the test results, the preoperative normal skin erythema value is about 21%, and the postoperative inflammatory redness and swelling of the skin erythema value is increased to about 30%, and after applying the mask material for 15 minutes, the original The inflammatory redness of the skin erythema decreased to about 21% of the same as before surgery.

In summary, the creation of the present invention is indeed in line with the industrial applicability, and is not found in the publication or public use before the application, nor is it known to the public, and has non-obvious knowledge, conforms to the patentable requirements, and is patented according to law. Application.

However, the above-mentioned statements are a preferred embodiment of the invention in the creation of the invention, and all the changes in the scope of the patent application according to the invention are within the scope of the claim.

Attachment 1 is the actual image and erythema value change of the subject before and after facial microneedle surgery on 2014/02/08, and 15 minutes after applying the mask material (from top to bottom, right) Face, face and left face).

Claims (7)

[Item 1] A masking agent comprising:
0.0001-0.001% by weight of Platonin,
3-15% by weight of Propylene Glycol,
3-15 wt% Butylene Glycol,
1-10% by weight of a thickener and 0.5-5% by weight of a bacteriostatic agent,
The rest is water and the total is 100% by weight. [Item 2] The masking agent according to claim 1, which further comprises 0.01-50% by weight of Placenta and 0.001-0.1% by weight of Glutathione. [Item 3] The masking agent according to claim 2, which further comprises:
0.5-5 wt% of Lactobacillus Ferment,
0.01-3 wt% oat kernel extract (Avena Sativa Kernel Extract),
0.01-0.1wt% of hyaluronic acid (Sodium Hyaluronate),
0.001-0.1 wt% of EGF growth factor (Oligopeptide-1),
And the Platonin, the Propylene Glycol, the Butylene Glycol, the thickener, the bacteriostatic agent, the placenta, the glutathione (Glutathione) The total of the Lactobacillus Ferment, Avena Sativa Kernel Extract, Sodium Hyaluronate and the EGF growth factor (Oligopeptide-1) is less than or equal to 100% by weight, if less than 100wt % is the rest of the water and the total is 100% by weight. [Item 4] The masking agent of claim 1, wherein the thickening agent is trehalose. [Item 5] The masking agent according to claim 4, further comprising 0.05-3 wt% of hydroxyethylcellulose (Hydroxyethyl Cellulose) and 0.05-3 wt% of xanthan gum (Xanthan Gum). [Item 6] The masking agent according to claim 1, wherein the bacteriostatic agent is 1,2-pentanediol (Pentylene Glycol). [Item 7] The masking agent according to claim 6 of the patent application, which further comprises:
0.001-3% by weight of Glyceryl Caprylate,
0.001-3% by weight of ethylhexylglycerol (Ethylhexylglycerin),
0.001-3% by weight of Caprylyl Glycol,
0.001-3% by weight of Dipropylene Glycol.