TW201540293A - Medical fluid container - Google Patents

Abstract

A medical fluid container of the present invention includes a container main body which is integrally molded by a blow-fill-seal method, a rubber plug which is disposed on a top surface of a mouth portion of the container main body, and an outer frame material which covers the rubber plug and the mouth portion, and which has a receiving surface that the mouth portion touches, and has a pressure bonding portion pressed in a direction of a bottom portion of the container main body against the mouth portion, and the rubber plug includes a plug main body covering a part of the top surface of the mouth portion, and a flanged portion extended between the pressure bonding portion and the mouth portion from a lower outer circumference of the plug main body.

Description

Liquid container

The present invention relates to a chemical liquid container having a container body formed by a blow-fill sealing method and a lid attached to a mouth portion of the container body.

Conventionally, as a container for a liquid medicine such as an infusion solution, a plastic bottle is known which is formed by a blow-fill-seal method (BFS). In the blow-fill sealing method, the formation of the bottle, the filling of the chemical liquid, and the sealing of the bottle are continuously performed in a common mold. This method is suitable for mass production of bottles and can be reduced in cost.

[Previous Technical Literature] [Patent Literature]

Patent Document 1: Japanese Patent Laid-Open No. 50-36290

Patent Document 2: European Patent No. 0364783

A cap is usually installed at the mouth of the BFS bottle. The cap is attached by, for example, disposing a rubber stopper on the top surface of the bottle and covering the rubber plug and the mouth of the bottle with the outer frame material, and then welding the outer frame material to the bottle.

However, as shown in FIG. 1 of Patent Document 1 or FIG. 2 of Patent Document 2, a conventional rubber plug (symbol 6 of Patent Document 1, symbol 5 of Patent Document 2) covers a bottle. The top surface is approximately the size of the entire top surface. In order to reduce costs, miniaturization of rubber plugs is required.

Further, since the rubber plugs have substantially the same thickness as a whole, it is difficult to press the peripheral portion of the rubber plug with sufficient strength between the bottle and the outer frame material. This insufficient crimping may cause liquid leakage when the rubber plug is needled.

It is an object of the present invention to provide a chemical liquid container which is reduced in size by miniaturization of a rubber plug, and which prevents leakage of liquid from the periphery of the rubber plug when the rubber plug is needled.

A chemical liquid container according to an embodiment of the present invention includes: a container body which is integrally formed by a blow-fill sealing method; a rubber plug which is disposed on a top surface of a mouth portion of the container body; a frame material covering the rubber plug and the mouth portion, and having a crimping portion having a bearing surface against which the mouth portion abuts, and being crimped to the container body with respect to the mouth portion In the bottom direction, the rubber plug has a plug body that covers one of the top surfaces of the mouth portion, and a flange portion that extends between the crimp portion and the mouth portion from the outer periphery of the lower portion of the plug body.

According to this configuration, since the portion of the rubber plug that is crimped by the mouth portion and the outer frame material is a relatively thin portion of the plug body, sufficient strength can be obtained between the mouth portion and the outer frame material (crimp portion). The crimp of the rubber plug is crimped. As a result, the rubber plug can be firmly held by the crotch portion. Therefore, when the needle body is needled, the movement of the rubber stopper can be suppressed, or the top surface of the mouth portion can be pressed by the rubber plug due to the movement to cause a large bending. Thereby, it is possible to prevent an excessive liquid from leaking in the outer frame material, thereby preventing liquid leakage from the periphery of the rubber plug.

In addition, the plug can be reduced because the amount of rubber material used in the crotch can be reduced. Since the main body is downsized, it is possible to reduce the cost corresponding to at least the reduction in usage.

In one embodiment of the present invention, the plug system of the rubber plug covers a central portion of a top surface of the mouth portion, and the crotch portion of the rubber plug covers a peripheral portion of a top surface of the mouth portion. The method is formed in a ring shape around the entire circumference of the plug body.

According to this configuration, the rubber plug is uniformly pressure-bonded to the entire circumference of the peripheral portion with sufficient strength. Thereby, liquid leakage can be prevented even at any portion around the rubber plug.

In one embodiment of the invention, the outer frame material has a projection that is embedded in the upper surface of the plug body of the rubber plug.

According to this configuration, the rubber plug can be pressed downward in accordance with the amount of protrusion of the protrusion of the outer frame material, so that liquid leakage can be prevented more satisfactorily.

In an embodiment of the invention, the protruding portion of the outer frame material is formed in a ring shape.

According to this configuration, the amount of protrusion of the protrusion corresponding to the outer frame material can be formed over the entire circumference of the rubber plug and pressed downward.

In one embodiment of the present invention, the plug system of the rubber plug has a protrusion that is deformed by pressing by the outer frame material.

According to this configuration, the rubber plug can be pressed downward in a length corresponding to the amount of protrusion of the projection of the plug body, so that liquid leakage can be prevented more satisfactorily.

In one embodiment of the present invention, the outer frame material includes an annular plate portion that faces the top surface of the mouth portion as a crimping portion that sandwiches the crotch portion of the rubber plug a peripheral portion; an upper portion that is integrally connected to an inner peripheral portion of the annular plate portion to cover the plug body; and a lower portion that is integrated In the manner, it is connected to the outer peripheral portion of the annular plate portion, and the mouth portion is covered.

According to this configuration, since it is clearly divided into a portion (upper portion and lower portion) covering the rubber plug and the mouth portion, and a pressure-bonding portion (annular plate portion), workability in crimping the flange portion can be improved.

In an embodiment of the present invention, the crotch portion of the rubber plug extends to an inner circumferential surface of the lower portion of the outer frame material.

According to this configuration, since the crimping area of the rubber plug can be increased, the degree of crimping of the rubber plug can be improved.

In one embodiment of the present invention, the mouth portion includes a crotch portion formed to surround the entire circumference at a position away from the top surface thereof, and the outer frame is welded to the crotch portion Under the material.

According to this configuration, since the outer frame material is fixed to the mouth portion, the state in which the rubber plug is crimped can be favorably maintained.

In an embodiment of the present invention, the lower portion of the outer frame material includes a crotch portion formed to surround the entire circumference thereof, and the crotch portion of the mouth portion is welded under the crotch portion of the outer frame material.

In one embodiment of the present invention, the depth h ₂ of the lower portion of the outer frame material is smaller than the sum of the height h ₁ from the crotch portion of the mouth portion and the thickness T ₄ of the crotch portion of the rubber plug.

According to this configuration, the crotch portion of the rubber plug can be satisfactorily crimped.

In an embodiment of the present invention, the crotch portion of the rubber plug has a thickness of 0.2 mm to 3 mm.

In an embodiment of the invention, the outer frame material includes a tab for opening the upper portion thereof.

1‧‧‧ liquid bottle

2‧‧‧ plastic bottle body

3‧‧‧ caps

4‧‧‧ Bottle body

5‧‧‧ mouth

6‧‧‧ scale

7‧‧‧ Spreader

8‧‧‧ neck

9‧‧‧ Tube

10‧‧‧Flange (internal)

11‧‧‧Top film

12‧‧‧ Rubber bolt

13‧‧‧Frame material

14‧‧‧ 栓 body

15‧‧‧Flange

16, 17‧‧ ‧ recess

18‧‧‧ oral department

19‧‧‧Rubber Plug Housing

20‧‧‧step (crimping)

21‧‧‧Flange

22‧‧‧ Protrusion

23‧‧‧ Pull ring

24‧‧ needle

25‧‧‧ liquid bottle

26‧‧‧ openings

27‧‧‧through hole

28, 29 ‧ ‧ gap

30‧‧‧ Protrusion

31‧‧‧ Protrusion

BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is a perspective view showing a liquid medicine bottle according to an embodiment of the present invention.

Fig. 2 is a schematic cross-sectional view showing the configuration of the periphery of the mouth of the liquid medicine bottle of Fig. 1.

Figure 3 is a schematic view of the bottom surface of the outer frame material.

Figure 4 is a view showing a portion of the mounting step of mounting the cover toward the mouth.

Figure 5 is a diagram showing a step below in Figure 4.

Figure 6 is a diagram showing a step in the lower part of Figure 5.

7A and 7B are views showing a state of use of the liquid medicine bottle of Fig. 1, Fig. 7A shows a state in which the needle is punctured to the rubber stopper, and Fig. 7B shows a state in which the liquid medicine bottle is inverted.

Figs. 8A and 8B are views showing the state of use of the liquid medicine bottle of the reference example, Fig. 8A shows the state in which the needle is punctured to the rubber stopper, and Fig. 8B shows the state in which the liquid medicine bottle is reversed.

9A and 9B are views showing a modification of the rubber stopper, Fig. 9A shows the state before the cover is mounted, and Fig. 9B shows the state after the cover is mounted.

Fig. 10 is a view showing a modification of the cover.

Embodiments of the present invention will be described in detail below with reference to the drawings.

Fig. 1 is a perspective view showing a liquid medicine bottle 1 according to an embodiment of the present invention. Fig. 2 is a schematic cross-sectional view showing the configuration of the periphery of the mouth portion 5 of the liquid medicine bottle 1 of Fig. 1. Figure 3 is a schematic view of the bottom surface of the outer frame material.

The liquid medicine bottle 1 as an example of the drug solution container of the present invention comprises a plastic bottle body 2 as an example of the container body of the present invention, and a bottle cap 3.

The plastic bottle body 2 integrally includes a bottle body portion 4 for accommodating the liquid medicine and The mouth portion 5 is placed at the top of the body portion 4. The cap 3 is attached to the mouth 5.

The plastic bottle body 2 integrally having the body portion 4 and the mouth portion 5 is produced by a blown fill seal (BFS) method.

For example, a parison is first produced by extrusion molding a material of the plastic bottle body 2.

The material to be used is not particularly limited as long as it is plastic, and examples thereof include polyolefin resins such as polyethylene, polypropylene, poly(4-methylpentene), and polytetrafluoroethylene, and ethylene-tetracyclic twelve. Preferred examples of the polycyclic olefin resin such as a olefin include polypropylene and a polycyclic olefin resin. Polyolefin resins such as polyethylene and polypropylene are generally low in dissolution properties for a wide variety of chemical solutions, and are general-purpose plastics. Therefore, the elution of impurities into the chemical solution can be suppressed, and the cost of the plastic bottle body 2 can be reduced.

Further, the materials used may be used singly or in combination of two or more. Further, the plastic bottle body 2 may be formed in a single layer structure or in a multilayer structure in which a plurality of layers of resin are laminated.

Then, the obtained parison is held by a separation mold to form a body portion 4 (forming step), and the inside of the body portion 4 is filled with a chemical liquid (filling step).

Next, the mouth portion 5 is formed by holding the separation mold, and the open end of the mouth portion 5 is sealed (sealing step) to obtain the plastic bottle body 2 containing the chemical liquid.

More specifically, each part of the plastic bottle body 2 will be described.

The body portion 4 is formed into an elliptical bottle shape in which the upper portion is tapered. A scale 6 for displaying the amount of the chemical liquid is provided on the outer peripheral surface of the bottle body 4 in the depth direction of the plastic bottle body 2. A spreader 7 for hanging the liquid medicine bottle 1 is formed at the bottom of the bottle body 4. The spreader 7 is formed, for example, in a flap shape protruding from the flat bottom of the body portion 4.

The mouth portion 5 is integrated with the body portion 4 via the neck portion 8 of the plastic bottle body 2 Connected sexually. The mouth portion 5 includes a substantially cylindrical tubular portion 9 and an annular plate-shaped flange portion 10 (ankle portion) formed on the entire circumference of the lower portion of the lower portion of the tubular portion 9.

The open end of the tubular portion 9 is sealed by a top film 11 formed by a sealing step. The top film 11 forms the top surface of the plastic bottle body 2. The top film 11 is formed to be thinner than the tubular portion 9 and the flange portion 10 and has a flexible portion. For example, as shown in FIG. 2, the thickness of each of the tubular portions 9 and the flange portion 10 of T ₁ and T ₂ of approximately 1.0mm ~ 2.0mm, whereas the thickness of the top film 11 of T ₃ is about 0.3mm ~ 0.6mm . The wall thickness difference is produced by making the plastic bottle body 2 by a blow-fill sealing method.

The cap 3 includes a rubber plug 12 and an outer frame material 13.

The rubber plug 12 is formed in a hat shape, and integrally includes a cylindrical plug body 14 and a ring-shaped flange portion 15 formed on the entire circumference of the outer periphery of the lower portion of the plug body 14.

Concave portions 16, 17 are formed in the center portions of the upper and lower surfaces of the plug body 14, respectively. The recess 16 and the recess 17 oppose each other to select the position of the plug body 14 to be thinner at this position. The through hole can be easily formed in the rubber plug 12 by piercing the needle with the recess 16.

The size of the plug body 14, for example, the height H ₁ is 3 mm to 7 mm, and the diameter D ₁ is 15 mm to 25 mm. In the case where the ratio (H ₁ /D ₁ ) of the height H ₁ to the diameter D ₁ is small, the shape of the plug body 14 may be defined as a disk shape. On the other hand, the size of the flange portion 15, for example, the thickness T ₄ is 0.2 mm to 3 mm, and the diameter D ₂ is 25 mm to 40 mm. Hereinafter, the extending width W _{1 of the} flange portion 15 is, for example, 5 mm to 15 mm.

Further, examples of the material of the rubber stopper 12 include a synthetic rubber such as butyl rubber or isoprene rubber, or a thermoplastic elastomer such as an olefin-based elastomer or a styrene-based elastomer. In particular, by injection molding the pair of rubber plugs 12 In the case of forming, it is preferred to use a thermoplastic elastomer.

The outer frame material 13 integrally includes a cylindrical mouth portion accommodating portion 18) (lower portion), a cylindrical rubber plug accommodating portion 19 (upper portion) having a smaller diameter than the mouth portion accommodating portion 18, and a joint port accommodating portion. The upper end of the 18 and the stepped portion 20 (crimped portion) of the annular plate shape at the lower end of the rubber plug housing portion 19. That is, the outer frame material 13 is configured as a second-order structure in which the rubber plug accommodating portion 19 is placed on the mouth accommodating portion 18 via the step portion 20.

A flange-shaped flange portion 21 is integrally formed on the outer periphery of the lower portion of the mouth accommodating portion 18 on Monday.

A projection 22 that protrudes downward in the axial direction of the rubber plug housing portion 19 is formed in the upper wall of the rubber plug housing portion 19. The projections 22 are formed, for example, in a ring shape having a thickness of about 0.5 mm to 2 mm and a height of about 1 mm to 3 mm.

Further, the inner region surrounded by the projections 22 on the upper wall of the rubber stopper accommodating portion 19 serves as a detachable tab 23 . The user opens the outer frame material 13 by pulling the pull-down ring 23 to expose the upper surface of the rubber plug 12.

The step portions 20 are perpendicularly connected to the inner circumference of the mouth accommodating portion 18 and the outer circumference of the rubber bolster accommodating portion 19, respectively, so as to have a horizontal plane perpendicular to the axial direction of the mouth accommodating portion 18 and the rubber plug accommodating portion 19. .

Further, as the material of the outer frame material 13, for example, a thermoplastic resin is preferable. Specifically, it is not particularly limited, and examples thereof include polyolefin (preferably polyethylene, polypropylene, etc.).

Next, a mounting method of attaching the cap 3 to the mouth portion 5 will be described.

4 to 6 are views showing the steps of mounting the cap 3 toward the mouth portion 5 in order.

First, as shown in FIG. 4, the cap 3 is assembled by fitting the plug body 14 of the rubber plug 12 into the rubber plug accommodating portion 19 of the outer frame material 13. The diameter of the rubber plug 12 (the diameter D _{2 of the} flange portion 15) may be substantially the same as the inner diameter D _{3 of the} mouth receiving portion 18. That is, on the assembled cap 3, the outer peripheral edge of the flange portion 15 of the rubber plug 12 can reach the inner peripheral surface of the mouth accommodating portion 18. According to this configuration, the pressure contact area of the flange portion 15 of the rubber plug 12 can be increased, so that the degree of crimping of the rubber plug 12 can be improved. Further, in this state, the projections 22 of the rubber stopper accommodating portion 19 may not be embedded in the upper surface of the plug body 14.

Next, after adjusting the position of the cap 3 relative to the mouth portion 5 of the plastic bottle body 2, the cap 3 is placed over the mouth portion 5 of the plastic bottle body 2.

Then, as shown in FIG. 5, the flange portion 21 (the crotch portion) of the outer frame material 13 abuts against the flange portion 10 of the mouth portion 5, and the plastic bottle body 2 is pressed. The mouth portion 5 and the outer frame material 13 are fixed by friction between the projection 31 provided on the cylindrical portion 9 and the inner peripheral surface of the mouth accommodating portion 18, but the lower surface of the flange portion 21 of the outer frame material 13 is used. It is preferable to weld and fix the flange portion 10 of the mouth portion 5 abutting on the flange portion 21. As the welding method, a known method such as heat sealing, ultrasonic welding, high-frequency welding, or the like can be employed. Further, in order to press the flange portion 15 of the rubber plug 12, it is necessary to adjust the height h ₁ of the mouth portion 5 and the depth h _{2 of the} mouth portion accommodating portion 18. That is, it is necessary to make the depth h ₂ higher degree h ₁ plus the total thickness T ₄ of the flange portion 15 of the rubber plug 12 slightly smaller. Thereby, the top film 11 of the mouth portion 5 is covered at the center portion by the plug body 14 of the rubber plug 12, and the peripheral portion is covered by the flange portion 15 of the rubber plug 12. At this time, since the step portion 20 is horizontally formed with respect to the axial direction of the mouth accommodating portion 18 and the rubber plug accommodating portion 19, the outer frame material 13 forms a clear second-order structure. By pressing the step portion 20, the force in the axial direction can be easily applied, so that workability in crimping the flange portion 15 can be improved.

In addition, the rubber plug 12 is also pressed by the press-in of the plastic bottle body 2. In. Thereby, the projection 22 of the rubber stopper accommodating portion 19 is fitted into the peripheral portion of the upper surface of the plug body 14, and is buried in the upper surface.

Next, as shown in FIG. 6, in order to fix the bottle cap 3 with respect to the mouth part 5, the mouth part 5 and the outer frame material 13 are welded. In the present embodiment, the flange portion 10 of the mouth portion 5 is welded to the lower surface of the flange portion 21 of the outer frame member 13.

After the steps described above, the installation of the cap 3 is completed.

Figs. 7A and 7B are views showing a state of use of the liquid medicine bottle 1 of Fig. 1, Fig. 7A shows a state in which the needle 24 is punctured to the rubber stopper 12, and Fig. 7B shows a state in which the liquid medicine bottle 1 is reversed. Figs. 8A and 8B are views showing a state of use of the liquid medicine bottle 25 of the reference example, Fig. 8A shows a state in which the needle 24 is punctured to the rubber stopper 12, and Fig. 8B shows a state in which the liquid medicine bottle 25 is reversed. 7A and 7B and FIGS. 8A and 8B show a state in which the pull-down ring 23 is taken and the opening 26 is formed in the outer frame material 13. In addition, in FIGS. 8A and 8B, the same component numbers are provided for the portions corresponding to the respective portions shown in FIGS. 7A and 7B.

First, the difference between the liquid medicine bottle 1 and the chemical liquid bottle 25 is that the chemical liquid bottle 25 does not have the step portion 20 of the outer frame material 13, and the rubber plug receiving portion 19 is substantially the same diameter as the mouth receiving portion 18 (slightly small diameter) )form. Further, the difference between the two portions is different in that the chemical liquid bottle 25 does not have the flange portion 15 of the rubber plug 12. Therefore, in the liquid chemical bottle 25, the rubber plug 12 (the plug body 14) having the diameter D ₄ substantially the same as the diameter D ₂ of the flange portion 15 of the rubber plug 12 of the liquid medicine bottle 1 is formed of the same thickness. Further, the tubular portion 9 directly abuts against the rubber stopper accommodating portion 19. Therefore, the rubber plug 12 of the liquid medicine bottle 25 is crimped between the mouth portion 5 and the outer frame material 13, and is instead contained in the rubber of the top film 11 and the outer frame material 13 of the mouth portion 5. The space enclosed by the plug receiving portion 19 is located.

Below, when using two liquid bottles 1 and 25 having such different points, No liquid leakage is indicated.

According to the liquid medicine bottle 1 of Figs. 7A and 7B, the portion of the rubber plug 12 which is crimped to the outer frame material 13 by the mouth portion 5 is the relatively thin flange portion 15 of the plug body 14. Therefore, the flange portion 15 of the rubber plug 12 can be pressure-bonded between the tubular portion 9 of the mouth portion 5 and the top film 11 and the step portion 20 of the outer frame member 13 with sufficient strength. As a result, the rubber plug 12 can be firmly held by the flange portion 15.

Therefore, as shown in FIG. 7A, when the needle 24 is inserted into the plug body 14 to form the through hole 27, the rubber plug 12 can be prevented from moving toward the inside of the mouth portion 5, or thus moved, causing the top film 11 to be pinned by the rubber plug 12. Pressing to bend large.

Thereby, as shown in Fig. 7B, even when the liquid medicine bottle 1 is used upside down, the close state of the rubber plug 12 and the top film 11 can be favorably maintained, and an excessive liquid leakage path can be prevented from being formed in the outer frame material 13. . As a result, it is possible to prevent liquid from leaking from the opening 26 via the periphery of the rubber plug 12.

Further, the upper surface of the plug body 14 is also filled with the projections 22 of the outer frame material 13, and the rubber plug 12 is pressed corresponding to the amount of projection of the projections 22. Thereby, in case the leaked liquid is also blocked, as a result, liquid leakage can be effectively prevented.

Further, by forming the rubber plug 12 into a hat shape, the amount of the rubber material used in the upper portion of the flange portion 15 can be reduced, and the plug main body 14 can be downsized. Therefore, it is possible to reduce the cost corresponding to at least the reduction in the amount of use. .

On the other hand, according to the liquid medicine bottle 25 of FIGS. 8A and 8B, since the step portion 20 (outer frame material 13) and the flange portion 15 (rubber plug 12) are not provided, the liquid medicine bottle of FIGS. 7A and 7B is provided. 1 comparison, the rubber plug 12 has a low degree of crimping.

Therefore, as shown in FIG. 8A, when the needle 24 is inserted into the plug body 14 to form the through hole 27, the rubber plug 12 is bent to move toward the inner side of the mouth portion 5, and thus moved. The top film 11 is caused to be pressed by the rubber stopper 12 to be largely bent.

Therefore, as shown in FIG. 8B, when the liquid medicine bottle 25 is used upside down, a large amount is generated between the rubber plug 12 and the top film 11 or between the rubber plug 12 and the outer frame material 13 (the rubber plug receiving portion 19). Clearances 28, 29. As a result, when liquid leakage occurs from the through hole 27, it is feared that the liquid easily conveys the gaps 28 and 29 as a liquid leakage path and leaks from the opening 26. Further, the rubber plug 12 is integrally formed by the thickness (height H ₁ ) of the plug body 14, so that the unit price of the rubber plug 12 is increased as compared with the liquid medicine bottle 1.

As can be seen from the comparison of FIGS. 7A and 7B with FIGS. 8A and 8B, according to the miniaturization of the rubber stopper 12, the cost can be reduced, and the circumference of the rubber plug 12 can be prevented during the needling. The liquid leaks.

Although the embodiments of the present invention have been described above, the present invention may be embodied in other forms.

The outer peripheral edge of the flange portion 15 of the rubber plug 12 may not reach the inner peripheral surface of the mouth accommodating portion 18.

Further, as shown in Fig. 9A, the liquid occlusion of the upper surface of the plug body 14 can also be formed by the projections 30 formed on the upper surface of the plug body 14. As shown in FIG. 9B, the protrusion 30 can also be deformed by being flattened by the outer frame material 13 in a state where the bottle cap 3 is mounted.

Further, in the liquid medicine bottle 1, the protrusions 22 and 30 may be omitted.

Further, as shown in FIG. 10, the connection port portion accommodating portion 18 and the step portion 20 of the rubber plug accommodating portion 19 may be provided so as to be inclined with respect to the axial direction of the accommodating portions 18, 19. In this configuration, the flange portion 15 of the rubber plug 12 can be satisfactorily bonded between the step portion 20 and the mouth portion 5, so that the aforementioned effects can be sufficiently exhibited.

Further, as the shape of the plastic bottle body 2, in addition to the above-described elliptical bottle shape, various bottle shapes such as a perfect round bottle shape and a square bottle shape may be used.

Further, as a member for detaching the rubber plug 12 until the time of use, and the rubber plug 12 is exposed during use, a protective film or the like may be used in addition to the above-described tab 23 .

In addition, various design changes can be implemented within the scope of the matters described in the patent application.

The present application corresponds to Japanese Patent Application No. 2014-62486, the entire disclosure of which is incorporated herein by reference.

2‧‧‧ plastic bottle body

3‧‧‧ caps

5‧‧‧ mouth

8‧‧‧ neck

9‧‧‧ Tube

10‧‧‧Flange (internal)

11‧‧‧Top film

12‧‧‧Plastic plug

13‧‧‧Frame material

14‧‧‧ 栓 body

15‧‧‧Flange

16, 17‧‧ ‧ recess

18‧‧‧ oral department

19‧‧‧Rubber Plug Housing

20‧‧‧step (crimping)

21‧‧‧Flange

22‧‧‧ Protrusion

23‧‧‧ Pull ring

31‧‧‧ Protrusion

Claims (13)

A medical liquid container comprising: a container body integrally formed by a blow-fill sealing method; a rubber plug disposed on a top surface of the mouth portion of the container body; and an outer frame material covering The rubber plug and the mouth portion have a pressure-bonding portion having a support surface on which the mouth portion abuts, and is pressed against the bottom portion of the container body with respect to the mouth portion, The rubber plug has a plug body that covers one of the top surfaces of the mouth portion, and a flange portion that extends between the crimp portion and the mouth portion from the outer periphery of the lower portion of the plug body. The liquid chemical container according to claim 1, wherein the plug system of the rubber plug covers a central portion of a top surface of the mouth portion, and the top portion of the rubber plug is a top surface of the mouth portion The peripheral portion is covered to form an annular shape around the entire circumference of the plug body. The chemical liquid container according to claim 1 or 2, wherein the outer frame material has a projection embedded in an upper surface of the plug body of the rubber plug. The chemical liquid container according to claim 3, wherein the protruding portion of the outer frame material is formed in a ring shape. The liquid chemical container according to claim 1 or 2, wherein the plug system of the rubber plug has a protrusion which is deformed by pressing by the outer frame material. The chemical liquid container according to claim 3, wherein the outer frame material comprises: an annular plate portion as the crimping portion, in a manner of sandwiching the crotch portion of the rubber plug And facing the peripheral portion of the top surface of the mouth; the upper portion is integrally connected to the inner peripheral portion of the annular plate portion to cover the plug body; and the lower portion is integrally connected to The outer peripheral portion of the annular plate portion covers the mouth portion. The chemical liquid container according to claim 5, wherein the outer frame material includes an annular plate portion that serves as the pressure-contact portion and faces the mouth portion so as to sandwich the crotch portion of the rubber plug a peripheral portion of the top surface; an upper portion integrally connected to the inner peripheral portion of the annular plate portion to cover the plug body; and a lower portion integrally connected to the outer circumference of the annular plate portion Department, cover the above mouth. The liquid chemical container according to claim 6, wherein the crotch portion of the rubber plug extends to an inner circumferential surface of the lower portion of the outer frame material. The medical liquid container according to claim 6, wherein the mouth portion includes a crotch portion formed to surround the entire circumference at a position away from the top surface thereof, and is directed to the crotch portion. The lower part of the outer frame material is welded. The liquid chemical container according to claim 9, wherein the lower portion of the outer frame material comprises a crotch portion formed around the entire circumference thereof, and the crotch portion of the mouth portion is welded to the outer frame material. The surface below the ankle. The liquid chemical container according to claim 10, wherein the depth h ₂ of the lower portion of the outer frame material is smaller than the height h ₁ of the crotch portion from the mouth portion and the thickness T ₄ of the crotch portion of the rubber plug. with. The pharmaceutical liquid container according to claim 1 or 2, wherein the rubber plug is The crotch portion has a thickness of 0.2 mm to 3 mm. The medical liquid container according to claim 1 or 2, wherein the outer frame material comprises a pull ring for opening the upper portion thereof.