TW201507688A - Suture for skin lifting or expanding the volume of skin tissue - Google Patents

Abstract

The present disclosure relates to a suture which, being inserted into skin, can lift skin and thus improve or remove skin wrinkles. The suture includes a through-hole which allows formation of new skin tissue and thus provides a (semi)permanently lasting effect of lifting skin and improving or removing wrinkles and has a shape of a sheet whose length is longer than its width. The present disclosure also relates to a suture which, being inserted into skin, can expand overall skin volume by inducing formation of new skin and adhesion between skin layers. The present disclosure also relates to a kit including the suture for lifting skin, which can expand overall skin volume.

Description

Suture used to lift or expand the volume of skin tissue

BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to a suture for peeling or expanding the volume of a skin tissue, and more particularly to a suture which can be inserted into a layer of skin, which pulls up the skin and forms skin tissue, thereby enticing between the layers of the skin. Adhesion is produced and the skin is kept in a pulled state, and wrinkles are removed and skin elasticity is enhanced by expanding the volume of the skin tissue.

As people age, wrinkles form on the face or body surface. Wrinkles are formed because muscles contract and the skin and fat layers sag due to gravity. The direction in which wrinkles are formed is perpendicular to the direction in which the muscles contract, and thus deepens with age.

The method of removing wrinkles can be mainly classified into chemical methods and physical methods.

One of the chemical methods is to use botulinum to make the muscles that cause wrinkles to become rigid. However, this method may result in an unnatural appearance and is difficult to use under the eyes, lower lip, nasolabial fold, and the like. Also, this method is limited to thick or deep wrinkles and the effect lasts only 3 to 6 months.

In terms of physical methods, one method is to fill the wrinkles with a filler. Although liquid fillers are convenient for injection, liquid fillers move toward muscle contraction as the muscles move, causing wrinkles to appear deeper and eventually absorbed by the body over time (about 1 to 2 years).

Another physical method is to insert an extremely thin gold wire into the subcutaneous layer. The gold wire will promote the growth of new tissues near the gold wire through the foreign matter reaction. However, this method is limited to thick wrinkles, and the inserted gold wire may be bent by an external force or protruded on the skin. Furthermore, because the gold wire is permanently left in the skin, it may cause interference when performing diagnostic medical imaging (eg, X-ray, CT, MRI, etc.).

Another physical method is the technique of pulling the skin by tightening the skin to remove wrinkles. However, wrinkles may reappear over time, and if the force applied at various portions of the three-dimensional contour of the face is different, wrinkles may not be uniformly removed. Although this method is effective against severe wrinkles, surgical techniques are less effective for the skin.

Accordingly, the present invention provides a suture capable of solving the above problems, which suture can be used not only for treating extremely severe wrinkles, but also for adults aged 20 to 40 years old and thin skin.

[References in Related Art]

Patent document

Patent Document 1: KR10-1256908 B1

The present invention provides a suture that is inserted into the skin to pull the skin and to improve or eliminate wrinkles in the skin.

The present invention also provides a suture for pulling the skin, the suture being permeable to one or more through holes that allow the formation of skin tissue and adhesion between the skin layers after insertion into the skin. The formation of new skin thus provides a (semi) permanent sustained skin pull-up effect and improves or removes wrinkles even after the suture itself has been broken down or absorbed.

The present invention also provides a suture for pulling the skin, which, after insertion into the skin, forms a new skin and thereby provides the effect of expanding the volume of the skin tissue.

In a broad aspect, the present invention provides a suture comprising one or more through holes that allow cells of nearby tissue to grow through the through holes to induce tissue formation and between skin layers Adhesion is produced to pull the skin and to improve or remove wrinkles, and the suture has a sheet shape having a length greater than the width.

In another general aspect, the present invention provides a kit comprising a suture for pulling the skin.

When inserted into the skin layer, the suture of the present invention can lift the skin and physically remove the wrinkles formed on the skin. The inserted suture induces cells of nearby tissue to grow into the suture and form new tissue. Therefore, it is possible to (semi-) permanently maintain the effect of pulling the skin and removing wrinkles.

Moreover, by inducing the formation of a new firm skin tissue, the suture of the present invention can prevent sagging of the skin and re-apprease of wrinkles due to gravity.

The suture of the present invention is along the length direction at the top side, the bottom side, the side edges or There may be one or more cogs at the edges of the cross section. The cog on the top side pulls the subcutaneous fat layer and the cog on the bottom side pulls the fascia layer. Therefore, the suture of the present invention differs from the current suture in that it can properly transmit force to each skin layer and can better pull the skin. In addition, the effect of pulling the skin or removing wrinkles is more durable.

Lifting the skin and forming new skin tissue provides the elasticity of the lower muscles to the epidermis, dermis and subcutaneous fat layer that sag due to gravity, thereby providing an effect of improving or removing skin wrinkles.

In addition, the suture of the present invention can effectively improve or remove wrinkles according to the three-dimensional contour of the face, and can provide a permanent improvement or remove the wrinkles of the skin, and can be used for people with weak wrinkles or skin which are extremely thin and thus relatively A person who produces wrinkles earlier.

In addition, the suture of the present invention provides an effect of improving or removing wrinkles by inducing the formation of new tissue cells and thereby expanding the volume of the skin tissue.

10‧‧‧ stitching

100, 101, 102, 103, 104, 105, 106‧‧‧ through holes

107, 108, 109, 110, 111, 112, 113‧‧‧ through holes

120, 130, 140, 150, 160‧‧‧ through holes

200, 210, 220, 221, 230, 231‧‧ ‧ teeth

232, 233, 240, 250, 251‧‧ ‧ teeth

252, 253, 254, 255, 256‧‧ ‧ teeth

300‧‧‧ Nodule

400, 410, 420, 430, 440 ‧ ‧ bolts

500‧‧‧ tube

Figures 1a through 1b are perspective views of sutures having through holes and a sheet shape having a length longer than the width.

Figure 2 is a perspective view of a suture having sides of a tubular shape and a cross-section having a dumbbell shape.

Figure 3 is a perspective view of a suture having a through hole in a mesh format.

Figures 4a through 4e illustrate plan views of mesh-shaped vias of different shapes.

Figures 5a through 5n illustrate a polygonal cross section of the suture and a deformed polygonal cross section.

Figures 6a through 6j illustrate circular, elliptical, deformed elliptical, and dumbbell-shaped cross-sections of the suture.

Figure 7 is a plan view of a suture having one or more nodules.

Figures 8a through 8c illustrate cross-sections of the sutures with thicker sides on either side of the suture.

Figures 9a through 9e are perspective views of sutures having one or more latches at the ends in the length direction.

Figures 10a through 10m are plan views showing different shapes of suture through holes.

Figures 11a through 11f illustrate cog positions in a suture having a rectangular cross section.

Figures 12a through 12f illustrate cog positions in a suture having a hexagonal cross section.

Figures 13a to 13d illustrate cog positions in a suture having a hexagonal cross-section, wherein both ends in the lengthwise direction are concavely curved, and a suture having a dumbbell-shaped cross section is illustrated.

Figures 14a through 14w are perspective views of sutures having cogs at the sides, top, bottom or edges.

Figures 15a through 15b illustrate sutures having cogs having a printed structure.

Figures 16a through 16f illustrate the position or arrangement of the cogs in the suture.

Figures 17a through 17g illustrate longitudinal sections of cogs in the suture.

In one aspect, the invention is directed to a suture having one or more through holes and a sheet shape having a length greater than a width.

In the present invention, "skin" means an organ covering the outer surface of a living being. The skin is composed of the epidermis, dermis and subcutaneous fat layers, and the term skin is used in the broadest sense. The skin includes not only tissues covering the face or body, but also the scalp and hair.

In the present invention, the term "suture" means a thread that can be inserted into the skin for medical or cosmetic purposes, and is not limited to the shape of the suture.

In the present invention, "tissue formation" means forming a new skin tissue to fill a skin layer or restore damaged skin tissue.

In the present invention, "skin layer" means one or more layers constituting the skin, and the term skin layer is used in the broadest sense, and the skin layer includes not only the epidermis, the dermis, and the subcutaneous fat layer. It also includes the skin fascia layer and the skin muscle layer.

In the present invention, "adhesion" means organic bonding between skin layers caused by insertion of sutures to induce tissue formation.

In the present invention, "lifting" means pulling or pulling the skin upward with a suture. The cogging, nodules, latches, etc. contained in the suture can be used to achieve the pulling action. The suture of the present invention can provide physical improvement or skin wrinkle removal effect by skin pulling action. Specifically, in an exemplary embodiment of the present invention, the suture can be inserted into a sagging skin, a dermis or a subcutaneous fat layer or a wrinkled skin, by means of cogs, nodules, plugs, etc. contained in the suture. The structure is used to pull the skin to unfold the wrinkles. Also, in an exemplary embodiment of the present invention, the suture can utilize a through hole to grow tissue cells in the vicinity And through the through holes to induce the formation of new skin tissue, so that wrinkles no longer appear. Therefore, by inducing the formation of a tight new skin tissue, the suture of the present invention can prevent skin sagging and wrinkle reproduction due to gravity.

In an exemplary embodiment of the invention, only the suture can be inserted into the skin and/or the suture can be pulled to provide an effect of improving or removing wrinkles by inducing the creation of new tissue cells and thereby expanding the volume of the skin tissue.

In the present invention, "volume" means the volume of the surface or interior of the skin layer and may mean the volume presented on the exterior. Therefore, skin with an expanded or increased volume will exhibit elasticity, health and youthfulness. Also, if a new skin tissue is formed at the wrinkle portion of the skin, the volume of the skin layer is increased, and thus the wrinkle portion is stretched out and wrinkles are spread, thereby removing wrinkles. In addition, in the case of skin damage, scars, depressions, surgical scars or the like caused by damage, trauma, burns, and the like, expanding the volume of the skin tissue may increase the volume of the skin layer and restore the skin to near the original state.

In the present invention, "expansion" means increasing the volume of the skin layer and may indicate an increase in the volume of skin presented on the exterior, resulting in a resilient, healthy appearance. If the volume of the skin tissue expands, the volume of the skin layer of the wrinkled skin increases, and the surface of the skin is spread out and the skin wrinkles are removed.

In the present invention, the term "wrinkle" is used in the broadest sense, including wrinkles caused by sagging of the skin due to age, ultraviolet (UV) and the like.

In the present invention, "sheet" means a material having a thickness smaller than a length and a thickness possibly equal to or less than a width, which material can be inserted into the skin.

In the present invention, "length" means the longest part of the sheet from one end The distance to the other end.

In the present invention, "width" means the longest line segment in the horizontal direction of the sheet in its cross section. In the present invention, "thickness" means the longest line segment in the vertical direction of the sheet in its cross section. The width and the thickness may have the same length.

In the present invention, "through-hole" means a hole penetrating one side and the other side of the lamellae suture.

In an exemplary embodiment of the invention, the through hole may be a hole through which cells of nearby tissues can grow to pass through the through holes, thereby inducing tissue formation and causing adhesion between the skin layers.

In an exemplary embodiment of the invention, the through hole may allow cells of nearby tissue to grow through the hole and form new tissue, thereby preventing the suture from falling and preventing wrinkle reproduction.

In an exemplary embodiment of the present invention, the through hole may have a shape of a polygon, a deformed polygon, a circle, a mesh, an ellipse, or a deformed ellipse. In particular, in an exemplary embodiment of the invention, the through hole may be a mesh format opening.

In an exemplary embodiment of the invention, the mesh opening may form an acute or right angle with respect to the width direction of the suture.

In the present invention, "polygon" means a shape having three sides or more sides. The polygon may include a triangle, a quadrangle, a rectangle, a parallelogram, a trapezoid, a diamond, a pentagon, a hexagon, and a hexagon that is convex or concavely curved at both ends in the length direction (see, Fig. 13c and Figure 13d), convex, concave, shape with one or more crosses (+ or ++), etc. However, it is not limited to the above shape.

In the present invention, "deformed polygon" means a shape composed of one or more straight line segments and one or more curved line segments. Examples include a triangle having a concave side, a triangle having a convex side, a quadrilateral having a convex side, a quadrilateral having a concave side, a polygon having one or more concave sides or convex sides, and having a convex bottom and The convex shape of the side, but is not limited to the above shape.

In the present invention, "circular" means a group of dots located at the same distance from a specified point, and the size of the circle differs depending on the diameter of the circle.

In the present invention, "elliptical" means a set of points in which the sum of the distances of the points to the two focal points is fixed, and the size of the ellipse differs depending on the sum size.

In the present invention, "deformed elliptical shape" means a circle or ellipse having one protrusion, a circle or ellipse having two protrusions, a circle or ellipse having three protrusions, a circle or ellipse having four protrusions a circle or ellipse or a closed curve with one or more depressions.

In the present invention, the "polygon" or "deformed polygon" includes not only a shape having a straight edge and a sharp apex angle, but also a shape in which a curved or convex side or a dome point is inevitably formed during manufacturing. For example, the suture can be treated to have curved or convex edges and dome points, as shown in Figure 13c, but is not limited thereto. Also, the above shape can be applied to the stitches of other exemplary embodiments of the present invention.

In the present invention, "dumbbell" means having a straight or curved shape The shape of the center and polygon, deformed polygon, round, elliptical or deformed elliptical end.

In an exemplary embodiment of the present invention, the suture may have a polygonal cross section, a deformed polygon, a circular shape, an elliptical shape, a deformed elliptical shape, or a dumbbell shaped longitudinal section at the end in the longitudinal direction.

In the present invention, "mesh" means a shape having one or more through holes formed by one or more straight lines or curved lines arranged in parallel, obliquely or vertically with respect to the longitudinal direction of the sheet. The horizontal or vertical side of the mesh aperture may form an acute or right angle with respect to the width direction of the suture. When the horizontal side or the vertical side forms a right angle with respect to the width direction, a pattern shape may be formed.

In the present invention, "modulus of elasticity" means the measurement of the deformation of the elastic material in response to stress, and means the modulus of elasticity measured according to a usual method in the related art.

In the suture according to an exemplary embodiment of the present invention, a mesh portion perpendicular to the longitudinal direction of the sheet may be formed of a highly elastic material, and a mesh portion parallel to the longitudinal direction of the sheet may be made of a low elastic material. form.

In an exemplary embodiment of the present invention, the high elastic material may have 300 MPa or more, 350 MPa or more, 400 MPa or more, 450 MPa or more, 500 MPa or more, 550 MPa or more, 600 MPa or more, Elastic modulus of 650 MPa or higher or 700 MPa or higher.

In an exemplary embodiment of the present invention, the low elastic material may have 200 MPa or less, 180 MPa or less, 160 MPa or less, 140 MPa or less, 100 MPa or less, 50 MPa or less, 30 MPa or less, 10 Elastic modulus of MPa or lower, 5 MPa or lower, 1 MPa or lower, or 0.1 MPa or lower.

In an exemplary embodiment of the present invention, the high elastic material may be Teflon, but is not limited thereto, and the low elastic material may be polypropylene or nylon, but is not limited thereto.

In an exemplary embodiment of the invention, the suture may have a polygonal, deformed polygonal, circular, elliptical, deformed elliptical or dumbbell shaped cross section.

In the present invention, "knot" means a knot having a suture of a sheet shape. The nodule can be formed by knotting the suture itself to form the nodule, and then pressing in a mold to form the nodule, forming the nodule integrally with the suture, or fabricating the suture and at the slit Individually made nodules are inserted in the line, but are not limited to the methods described above.

In an exemplary embodiment of the invention, the suture may have one or more nodules.

In an exemplary embodiment of the invention, the sutures are thicker at the both side edges in the width direction than at the center.

In an exemplary embodiment of the present invention, the sheet may be 1% to 100% thicker than the center at both side edges in the width direction. In an exemplary embodiment of the present invention, the sheet may be 5% or more, 10% or more, 15% or more, 20% or more thicker than the center at both sides in the width direction. 25% or more, 30% or more, 35% or more, 40% or more, or 45% or more. In an exemplary embodiment of the present invention, the sheet may be 95% or less, 90% or less, 85% or less, 80% or less thicker than the center at both sides in the width direction. , 75% or less, 70% or less, 65% or less, 60% or more Less, 55% or less or 50% or less.

In an exemplary embodiment of the invention, the suture has a tubular shape on both sides along the length of the sheet. The tube may be solid or hollow and may have a circular, elliptical, deformed elliptical, polygonal, deformed polygonal or dumbbell shaped cross section.

In the present invention, "average size" means, in terms of a polygon, the average length of all sides or all diagonals. In the case of a deformed polygon, the average size means the length of the longest line segment passing through the center. In the case of a circle or an ellipse, the average size means the length of the longest line segment passing through the center of a circle or an ellipse. In the case of a deformed ellipse, the average size means that five average lengths of the line segments passing through the center of the deformed ellipse (including the longest line segment and the shortest line segment) are randomly selected. In the case of a dumbbell shape, the average size means the length of the longest line segment passing through the center of the dumbbell.

In an exemplary embodiment of the invention, the through hole may have an average size of 0.01 mm to 10 mm. In an exemplary embodiment of the present invention, the through hole may have 0.01 to 4 mm, 0.05 to 9 mm, 0.1 to 8 mm, 0.5 to 7 mm, 1 to 6.5 mm, 1.5 to 6 mm, and 2 to 5.5 mm. Average size of 3 to 5 mm or 3.5 to 4.5 mm. Specifically, in an exemplary embodiment of the present invention, the through hole may have 0.01 mm or more, 0.05 mm or more, 0.1 mm or more, 0.15 mm or more, 0.2 mm or more, 0.3. Millimeter or more, 0.5 mm or more, 1 mm or more, 2 mm or more, 3 mm or more, 3.5 mm or more, 4 mm or more, 4.5 mm or more, 5 mm or Larger, 6 mm or larger, 7 mm or larger, 8 mm or larger, 9 mm or larger, 10 mm or larger, or 15 mm or larger average size, and may have 20 mm or less , 15 mm or less, 13 mm or Smaller, 10 mm or less, 9 mm or less, 8 mm or less, 7 mm or less, 6 mm or less, 5 mm or less, 4 mm or less, 3 mm or less An average size of 2 mm or less, 1 mm or less, 0.5 mm or less, 0.1 mm or less, or 0.01 mm or less.

In an exemplary embodiment of the invention, the suture may have a width of from 0.1 mm to 50 mm. In an exemplary embodiment of the invention, the suture may have a width of from 0.5 mm to 10 mm. In an exemplary embodiment of the invention, the suture may have 0.1 mm or more, 0.5 mm or more, 1 mm or more, 2 mm or more, 3 mm or more, 4 mm or more. Width of 5 mm or more, 10 mm or more, 15 mm or more, 20 mm or more, 25 mm or more. In an exemplary embodiment of the invention, the suture may have 50 mm or less, 45 mm or less, 40 mm or less, 30 mm or less, 27 mm or less, 25 mm or less. , 20 mm or less, 15 mm or less, 10 mm or less, 5 mm or less, 1 mm or less, or 0.1 mm or less in width.

In an exemplary embodiment of the invention, the suture may have a thickness of 0.001 mm to 10 mm. In an exemplary embodiment of the invention, the suture may have a thickness of 0.1 mm to 5 mm. In an exemplary embodiment of the invention, the suture may have 0.005 mm or more, 0.01 mm or more, 0.05 mm or more, 0.1 mm or more, 0.5 mm or more, 1 mm or more. , 2 mm or more or 3 mm or more. In an exemplary embodiment of the invention, the suture may have 10 mm or less, 9 mm or less, 8 mm or less, 7 mm or less, 6 mm or less, 5 mm or less. , 4 mm or less, 3 mm or less, 2 mm or less, 1 mm or less or 0.1 mm or less in thickness.

In the present invention, "cog" means a structure in which a sheet is fixed or hooked to a skin layer when it is inserted into the skin. The coggs may be formed by cutting the both sides of the sheet, or integrally formed cogs that are separated from the sides of the sheet, but are not limited to the above.

In particular, in an exemplary embodiment of the invention, the cogs may be secured to the fascia layer and the subcutaneous fat layer when the cogs are pulled or pulled. Therefore, the suture according to an exemplary embodiment of the present invention can transmit power to each skin layer well and can provide an effect of effectively pulling out the skin or removing wrinkles, and the effect can last for a long time.

In an exemplary embodiment of the present invention, the cogs may be formed by projecting the cogs from the suture, integrally forming the cogs with the sutures, or making the sutures and forming the inlays separately. The teeth are attached to the suture but are not limited to the methods described above. Specifically, in an exemplary embodiment of the present invention, the cogs may be protruded from the suture by cutting or engraving a portion where the cogs are to be placed. In particular, in an exemplary embodiment of the invention, when the suture has a cross section of a polygonal or deformed polygon, the cog can be formed by cutting or engraving the edge of the suture. When the suture has a circular, elliptical, deformed elliptical or dumbbell-shaped cross section, the cogs can be formed by engraving a thicker portion than the other portions. For example, when the suture has a hexagonal cross section, cogs as shown in Fig. 12f and Figs. 14n to 14q can be formed. When the suture has a dumbbell-shaped cross section, a cog as shown in Fig. 13d can be formed.

In an exemplary embodiment of the invention, the suture may have one or more cogs.

In an exemplary embodiment of the invention, the cogs can pull up the skin layer when the cogs are inserted into the skin.

In an exemplary embodiment of the invention, the cogs may have the same thickness or a smaller thickness than the ends of the width of the suture.

In an exemplary embodiment of the invention, the cogs may have a thickness of 1% to 100% compared to both ends of the width of the suture. In an exemplary embodiment of the invention, the cogs may have 5% or greater, 10% or greater, 15% or greater, 20% or both compared to the ends of the width of the suture. Thicker, 25% or greater, 30% or greater, 35% or greater, 40% or greater or 45% or greater and 95% or less, 90% or less, 85% Or smaller, 80% or less, 75% or less, 70% or less, 65% or less, 60% or less, 55% or less, or 50% or less.

In an exemplary embodiment of the invention, when the suture has a polygonal cross section, the cogs may be located at the sides, vertices or edges of one or more of the polygons.

In an exemplary embodiment of the invention, the suture may have a square or rectangular cross section.

In an exemplary embodiment of the invention, the suture may have a top side cog, a bottom side cog, and a side cog. Specifically, the top side cogs, the bottom side cogs, and the side cogs each represent cogs at the top, bottom, and side portions of the suture. For example, when the suture has a polygonal cross section, the top side cogs can be positioned at the top side of the polygon or at the top corner of the top side of the polygon. This configuration also applies to the underside cogs and side cogs.

In an exemplary embodiment of the invention, the cogs are positionable along the length direction On one or more of the two sides or the top side and the bottom side of the sheet. When the suture has a polygonal cross section, the cog can be further positioned at one or more apex angles of the polygon.

In particular, in an exemplary embodiment of the invention, the cogs may be located at the top and bottom sides of the sheet, or at the edges of the top and bottom sides, along the length direction. The top side cog can pull the subcutaneous fat layer, and at the same time the bottom side cog can pull the fascia layer. Therefore, the force can be appropriately transmitted, and the effect of continuously pulling the skin or removing wrinkles can be achieved for a long time. Specifically, the top side and the bottom side of the sheet in the longitudinal direction are determined with respect to the longest line segment passing through the center of the sheet.

In particular, in an exemplary embodiment of the invention, the cogs may be located at the top and bottom sides of the sheet along the length direction. More specifically, the cogs can be positioned along the length of the edges of the top and bottom sides of the sheet.

In an exemplary embodiment of the invention, the side cogs located at the sides of the sheet along the length direction can pull the fibrous tissue between the subcutaneous fat layer and the fascia layer.

Specifically, in an exemplary embodiment of the present invention, when the suture has a rectangular cross section, the cogs may be positioned at both the top side and the bottom side of the sheet along the length direction. More specifically, in an exemplary embodiment of the present invention, when the suture has a rectangular cross section, the cogs may be located at two sides and both side edges of the top and bottom sides of the sheet along the length direction. More specifically, in an exemplary embodiment of the invention, the cogs may be located at the edges of the top and bottom sides and at the edges of the two sides. If the cogs are arranged in various directions, at the same time, the top side cogs can pull the subcutaneous fat layer, the bottom side cogs can pull the fascia layer, and the position The side cogs at the sides are capable of pulling the fibrous tissue between the subcutaneous fat layer and the fascia layer. Since such sutures also pull up fibrous tissue, such sutures can exhibit a more effective and significant pull-up or wrinkle-removing effect.

More specifically, in an exemplary embodiment of the present invention, when the cogs at the bottom side portion in contact with the portion to be pulled have a printed structure, the top side cogs can be pulled at the same time. A subcutaneous fat layer, and the bottom side cog can pull the fascia layer. Further, the cogs located on the top side portion at the opposite side of the bottom side portion may be fixed to the fascia layer and the subcutaneous fat layer at the top of the face or to the fascia fascia. In this case, since the cogs having the printing structure can prevent the suture from falling due to gravity after the suture is inserted, the effect of more effective and long-lasting stretching of the skin or removal of wrinkles can be achieved.

In an exemplary embodiment of the invention, the cogs may have one or more printed structures. In particular, in an exemplary embodiment of the present invention, the cogs may have one or more, two or more, three or more, four or more, five or more , six or more, seven or more, eight or more, nine or more, or ten or more printed structures, but are not limited thereto.

In particular, in an exemplary embodiment of the invention, the suture may comprise cogs having one or more printed structures, and the suture comprising cogs having one or more printed structures may be uniform and integral Lift the skin (not partially). For example, a suture comprising a cog having two printed structures may have a shape as shown in Figs. 15a to 15b, but is not limited to such a shape.

In the present invention, "decalcomania structure" means a configuration in which one or more cogs are arranged relative to the center of the printing structure. Face to face or back to back structure. In an exemplary embodiment of the invention, the cogs may have one or more printed structures.

In an exemplary embodiment of the invention, the cogs at one side of the sheet and the cogs at the opposite sides may be configured in the same or opposite directions.

In an exemplary embodiment of the invention, the cogs may have sharp, hooked, curved, polygonal or deformed polygonal ends. The hook shape can have a bent end.

In an exemplary embodiment of the invention, the cogs at the sides of one of the sheets and the cogs at the opposite sides may be configured in the same or opposite directions. When the cogs at the sides of one of the sheets and the cogs at the opposite sides are arranged to be reversed, the cogs may be located at the sides of the width of the sheet at the top of the width of the sheet At the side and bottom side, or at one or more edges of the sheet. When the cogs are located at the top and bottom sides of the width, one side of the cogs can be fixed to the upper skin layer relative to the plane of the skin incision, and the cogs on the opposite side can be fixed to the lower skin layer. For example, the cogs on one side can be fixed to the subcutaneous fat layer to lift the skin and spread the wrinkles, and after pulling the skin, the cogs on the opposite side can be fixed to the fascia layer, thereby preventing the skin from being again Drooping.

In the present invention, a "latch" is different from a cog. In view of the fact that one or more cogs are located at the sides, edges, etc. of the width of the suture and are used to secure the suture, the pin is at the end in the length direction, and the size and thickness of the pin are larger than the cogs. .

In an exemplary embodiment of the present invention, a mold can be utilized to form a unitary body The pin in the suture is formed in a form, or the pin can be attached to the suture after the pin is separately manufactured, but is not limited to the above.

In an exemplary embodiment of the invention, the suture may have one or more latches at the ends in the length direction. In an exemplary embodiment of the invention, the pin can be positioned at the same location as the cog.

In an exemplary embodiment of the invention, the plug can be inserted into the skin and pulled up the skin layer.

In the present invention, the "growth factor" may be platelet-derived growth factor (PDGF), angiogenic factor (AGF), fibroblast growth factor (FGF), transforming growth factor-α (TGF-α), transformation growth. Factor-β (TGF-β), epidermal growth factor (EGF), connective tissue growth factor (CTGF), vascular endothelial growth factor (VEGF), and the like, but not limited to those described above.

In an exemplary embodiment of the invention, a growth factor may be contained on or in the surface of the suture.

In an exemplary embodiment of the invention, the suture may be formed partially or entirely of a biodegradable polymer, a bio-insoluble polymer or a combination of the above.

In an exemplary embodiment of the invention, the suture may be formed from one or more biodegradable polymers selected from the group consisting of polyglycolic acid (PGA), hyaluronic acid, HA), polylactic acid (PLA), poly(lactic-co-glycolic acid, PLGA) and polydioxanone (PDS), but not limited to the above The polymer.

In an exemplary embodiment of the invention, the suture may be selected from the following One or more biodegradable polymers in the group: polyethylene, polypropylene, poly(propyl vinyl), nylon (nylon), silicone, and Teflon, but not Limited to the polymers described above.

The sutures according to an exemplary embodiment of the present invention can be inserted into the skin layer in accordance with methods commonly used in the art.

In an exemplary embodiment of the invention, the suture may be integrally formed.

In another aspect, the present invention is directed to a kit comprising a suture and a needle made in accordance with an exemplary embodiment of the present invention.

In an exemplary embodiment of the invention, the kit may further comprise an adhesive means for attaching to the fascia.

In an exemplary embodiment of the present invention, the adhesive attached to the fascia may be a mesh, a gauze or a thin plate, but is not limited to the above-described utensils as long as the appliance can be attached to the fascia And can fix the suture.

In an exemplary embodiment of the invention, the kit further includes instructions describing a method of using the suture.

In an exemplary embodiment of the invention, the method of using the suture is as follows:

1. Insert a needle that allows the suture to pass between the subcutaneous fat layer that has been cut open and the fascia.

2. Adjust the position of the inserted needle to the position of the skin where the suture is to be inserted. Adjust the direction and position of the needle with one hand.

3. After the needle is at the desired location, the suture is inserted through the needle into the skin.

4. Adjust the suture so that the suture is positioned and only remove the needle from the skin. The end of the suture is fixed to the skin.

5. Use the stitches that have been inserted into the skin to pull the skin wrinkles away.

6. If the position of the suture is fixed, the suture is attached to the adhesive attached to the fascia fascia, and the suture is fixed so that the suture does not come out over time.

7. Suture the cut skin.

Hereinafter, a suture according to an exemplary embodiment of the present invention will be described in detail with reference to the accompanying drawings.

The exemplary embodiments shown in the figures are for illustrative purposes only and are not intended to limit the scope of the invention.

Figure 1a is a perspective view of a suture 10 according to the present invention, the suture 10 comprising one or more through holes 100 through which cells of nearby tissue can grow to induce tissue formation and skin layers Adhesion occurs between them to prevent sagging of the skin and wrinkles, and the suture has a sheet shape having a length longer than the width.

The suture 10 according to the present invention may have a sheet shape having a length longer than the width so that the suture can be inserted into the skin. Moreover, the suture may have a through hole 100, and cells of the nearby tissue can grow and pass through the through holes, thereby inducing tissue formation and adhesion between the skin layers, thereby preventing skin sagging and wrinkle reproduction, and Expand the total volume of the skin.

Figure 1b is a perspective view of a suture according to the present invention, the suture further comprising one or more cogs 200.

Since the suture 10 according to the present invention further includes one or more cogs 200, after the suture 10 is inserted into the skin, the cogs are fixed to one or more skin layers so that the suture 10 can be secured. So that the stitching will not be out of the way Move and move. Again, after the cogs 200 are secured to one or more skin layers, the cogs 200 enable the suture 10 to pull the skin. Therefore, skin wrinkles can be spread out.

2 is a perspective view of a suture 10 according to the present invention having both sides of a circular tube 500 along a length of the sheet and having a dumbbell-shaped cross section, the suture 10 containing one or more Through holes 100 and cogs 210, and the dumbbell shape has a circular cross section.

The cogs according to the present invention may have the same thickness as the ends of the suture in the longitudinal direction (such as the cogs 200 shown in Figure 1b), or the cogs may be thinner than the ends of the sutures ( The cog 210) as shown in Fig. 2.

Figure 3 is a perspective view of a suture 10 according to the present invention having sides of a circular tube 500 along the length of the sheet, and the suture 10 includes one or more mesh-format through holes 110 and Cog 210.

In an exemplary embodiment of the present invention, the tube located at both side edges along the length direction of the sheet may have a circular shape, and may have a polygon like the outer surface after the sheet is removed from the cog. The shape of the deformed polygon, the elliptical shape, or the deformed elliptical shape (as shown in FIGS. 5a to 5n and FIGS. 6a to 6j), but is not limited to the shape described above.

4a to 4e are plan views illustrating mesh-shaped through holes of different shapes. Figure 4a illustrates a mesh-format via 120 formed in line with the longitudinal direction of the sheet. Figure 4b illustrates a mesh format via 130 formed perpendicular to the length of the sheet. Fig. 4c illustrates a mesh-format through hole 140 formed by a straight line toward the upper right side, and Fig. 4d illustrates a mesh-format through hole 150 formed by a straight line toward the lower right side. Figure 4e illustrates a mesh-format via 160 that is formed by overlapping the tilts of the two directions to form a mesh.

Not limited to the mesh-format through-holes shown in FIG. 3 and 4a to 4e, a combination of a curve or a curve and a straight line may be used to form the mesh.

Figures 5a through 5n illustrate a suture 10 of the present invention having one or more cogs 210 and a cross section having a polygonal or deformed polygon. In each of the figures, a shaded portion corresponds to a stitch portion that is not penetrated by the through hole 100, and an unshaded portion corresponds to one or more through holes 100. Fig. 5a illustrates a square cross section, Fig. 5b illustrates a rectangular cross section, Fig. 5c illustrates a rhombic cross section, Fig. 5d illustrates a parallelogram cross section, and Fig. 5e illustrates a trapezoidal cross section, Fig. 5f A pentagonal cross section is shown, a 5th diagram illustrates a hexagonal cross section, a 5h diagram illustrates a convex cross section, a 5th diagram illustrates a cross-shaped cross section, and a 5j diagram illustrates a double cross-shaped cross section. As a cross section of the deformed polygon, FIG. 5k illustrates a triangular cross section having a concave side, FIG. 5l illustrates a quadrangular cross section having a convex side, and FIG. 5m illustrates a quadrangular cross section having a concave side, and Figure 5n illustrates a cross section with a convex bottom side and a convex side.

Figures 6a through 6j illustrate a suture 10 of the present invention having one or more cogs 210 and a cross-section having a circular, elliptical or deformed elliptical shape. Figure 6a illustrates a circular cross section, Figure 6b illustrates an elliptical cross section, Figure 6c illustrates a dumbbell shaped cross section with a rectilinear center, and Figure 6d illustrates a dumbbell shaped cross section with a convex center . Figure 6e illustrates a deformed elliptical cross section with a protrusion, Figure 6f illustrates a deformed elliptical cross section with two protrusions, and Figure 6g illustrates a deformed elliptical cross section with three protrusions, Figure 6h illustrates a deformed elliptical cross section with four protrusions, Figure 6i illustrates a deformed elliptical cross section as a closed curve, and Figure 6j illustrates another A curved, deformed elliptical cross section.

Figure 7 is a plan view of a suture 10 according to the present invention comprising one or more through holes 100 and one or more nodules 300. In this embodiment, the nodule is formed by knotting the suture itself.

8a to 8c illustrate a cross section of a suture 10 according to the present invention, the suture 10 comprising one or more through holes 100 and one or more cogs 210, wherein the sheets are along the length The thickness at the sides of the sides is greater than the thickness at the center. In these figures, the shaded portions correspond to the portions of the stitches that are not penetrated by the through holes 100, and the unshaded portions correspond to the one or more through holes 100. In the cross section illustrated in Fig. 8a, the center of the suture is concave and the thickness at both side edges along the longitudinal direction of the sheet is large. In the cross section illustrated in Fig. 8b, the top side and the bottom side in the longitudinal direction of the sheet are concave and the both sides have a large thickness. In the cross section illustrated in Fig. 8c, the both side edges of the cross section shown in Fig. 8a are formed in a convex shape.

In an exemplary embodiment of the present invention, the suture cross section having a thickness on both sides of the sheet larger than the center thickness of the sheet in the longitudinal direction may be a dumbbell shape as shown in Figs. 6c to 6d.

Figures 9a through 9e are perspective views of a suture 10 according to the present invention, the suture 10 including one or more through holes 100 and further including one or more pins 400 at the ends in the lengthwise direction . Figure 9a illustrates that the suture 10 includes a pin 400 at one end, and Figure 9b illustrates that the suture 10 includes a pin 410 at both ends, and Figure 9c illustrates the suture 10 having an L-shaped end and including at one end Two pins 420, Illustrated in Figure 9d, the suture 10 includes two latches 430 located at the ends, one latch facing upward and the other latch facing down Square, and Figure 9e illustrates that the rectangular stitch 10 includes two latches 440 located at the sides of one end, respectively.

Figures 10a through 10m are plan views of a suture 10 according to the present invention, the suture 10 comprising one or more through holes 100 of different shapes. Fig. 10a illustrates a circular through hole 100, Fig. 10b illustrates a small circular through hole 101, Fig. 10c illustrates a triangular through hole 102 which is alternately arranged, and Fig. 10d illustrates a triangular through hole arranged in a side by side configuration 103, FIG. 10e illustrates a quadrangular through hole 104, a 10fth diagram illustrates a rhombic through hole 105, a 10th diagram illustrates a pentagonal through hole 106, and a 10hth diagram illustrates a hexagonal through hole 107, a 10ith diagram A quadrangular through hole 108 having a concave surface (which can be used as an example of a deformed polygon) is shown, an elliptical through hole 109 is illustrated in Fig. 10j, and a deformed elliptical through hole 111 having a protruding portion is illustrated in Fig. 10k, Fig. 10l The grid pattern through holes 112 are shown as mesh-type through holes, and the 10m-mapping diagram is a mesh-shaped through-hole 113 in which the oblique lines in the two directions are overlapped to form a mesh.

Figures 11a through 11f illustrate the cog positions in the suture 10 of the present invention having a rectangular cross section. Figure 11a shows the cogs 220 at both ends of the same side, Figure 11b shows the cogs 220 at opposite sides in the opposite direction, and Figure 11c shows the cogs 220 at all edges. Figure 11d illustrates the cogs 220 at all edges and at the sides along the length of the suture. Figure 11e shows the cogs 220 at the top and bottom sides. Figure 11f illustrates the suture including cogs 220 positioned at the top and bottom sides and further including cogs 221 positioned at the sides. Although only sutures having a rectangular cross section are shown in the figures, other sutures having a polygonal cross section may also include cogs that are configured in the manner described above.

Figures 12a through 12f illustrate the cog positions in the suture 10 of the present invention having a hexagonal cross section. A suture having such a cross section is characterized in that both side edges of the suture project out along the length direction. This feature makes it easy to form cogs at the sides. Figure 12a shows that the cogs 220 are at the two ends of the same side, the 12b shows the cogs 220 at the opposite sides in the opposite direction, and the 12c shows the cogs 220 in addition to the sides. All vertices outside. Figure 12d illustrates a suture comprising cogs 220 at all vertices and further including cogs 221 at both sides along the length of the suture. Figure 12e illustrates a suture comprising cogs 220 at the top and bottom sides and further including cogs 221 at the sides. Fig. 12f illustrates that the two sides of the projection are cut in accordance with the broken line in the longitudinal direction to form the cogs 221 located at the both side edges in the longitudinal direction. This cutting step can be performed not only at the vertices of the side edges, but also at all other point tops to form new cogs.

Figures 13a through 13d illustrate the cog positions in the suture 10 of the present invention having different cross sections. Figure 13a illustrates a suture having a hexagonal cross-section, wherein both ends in the lengthwise direction are concavely curved and include cogs 220 at the apex of the top and bottom sides of the suture. Figure 13b illustrates that the suture further includes cogs 221 located at both ends along the length in addition to the cogs 220 shown in Figure 13a. Figure 13c illustrates a suture having a hexagonal cross-section, wherein both ends in the lengthwise direction are treated to be convex and have rounded ends, and the sutures are located at the ends of the top and bottom sides The cogs 220 and the cogs 221 at the sides. The section shown in Fig. 13c belongs to the "polygon" or "deformed polygon" defined in the present invention. It may inevitably form a shape with a convex side and a rounded end during the process. shape. The above appearance can also be applied to the sutures of other exemplary embodiments of the present invention. Figure 13d illustrates a suture having a dumbbell-shaped cross-section in which the dumbbell portion is cut along a dashed line to form outwardly projecting cogs 220 and cogs 221.

Figures 14a through 14w illustrate perspective views of a suture 10 of the present invention, the suture 10 including cogs 230 positioned along the lengthwise sides, top and bottom sides or edges of the suture sheets . The suture shown in Fig. 14a has a central portion of the cross section that is concave and has a thickness greater than the thickness of the center and includes one or more cogs 230 at the sides of the suture. Figure 14b illustrates a suture having an elliptical cross-section, and the suture includes one or more cogs 230 at the two sides. Figure 14c illustrates a suture having a dumbbell-shaped cross-section with the center of the suture being linear and including one or more cogs 230 at the sides. Figures 14d through 14k illustrate perspective views of sutures having a rectangular cross section. Figure 14d illustrates a suture comprising cogs 230 and through holes 100 at the top and bottom sides along the length of the suture, wherein the cogs at the top and bottom sides are arranged in the same direction. Figure 14e illustrates a suture comprising cogs 230 and through holes 100 at the edges of the suture, wherein the cogs at the edges are arranged in the same direction. Figure 14f illustrates a stitch comprising cogs 230 and through holes 100 at the top and bottom sides along the length direction, wherein the cogs at the top and bottom sides have a printed configuration different from that of Figure 14d. Figure 14g illustrates a stitch comprising a cog 230 and a through hole 100 at the edge, wherein the cogs at the edge have a printed structure. Figure 14h illustrates a stitch comprising a cog 230 positioned at a top side and a bottom side along a length direction, a cog 231 at a side edge along a length direction, and a through hole 100, wherein the cogs are configured the same way.

When the cogs are located on the top side and bottom as shown in Figures 14e to 14g At the edge of the side, at the same time, the top side cogs can pull the subcutaneous fat layer and the bottom side cogs can pull the fascia layer. In particular, when the cogs at the bottom side portion in contact with the portion to be pulled have a printed structure, at the same time, the top side cogs can pull the subcutaneous fat layer and the bottom side cogs can pull the fascia layer. Further, the cogs located on the top side portion at the opposite side of the bottom side portion may be fixed to the fascia layer and the subcutaneous fat layer at the top of the face or to the fascia fascia. In this case, since the cogs having the printing structure can prevent the suture from falling due to gravity after the suture is inserted, the effect of more effective and long-lasting stretching of the skin or removal of wrinkles can be achieved.

Figure 14i illustrates that the suture includes cogs 230 located at the top and bottom sides along the length direction, cogs 231 and through holes 100 at the sides along the length direction, wherein the cogs have a printed structure . Figure 14j illustrates that the suture includes cogs 230 at the edges of the top and bottom sides along the length direction and cogs 231 and through holes 100 at the sides, wherein the cogs are arranged in the same direction . Figure 14k illustrates that the suture includes cogs 230 at the edges of the top and bottom sides along the length direction and cogs 231 and through holes 100 at the sides, wherein the cogs have a printed configuration.

Figures 14l through 14q illustrate perspective views of sutures having a hexagonal cross section. Figure 14l illustrates that the suture includes cogs 230 at the edges of the top and bottom sides of the suture along the length direction and cogs 231 and through holes 100 at the sides, wherein the cogs are configured the same way. Figure 14m illustrates that the suture includes cogs 230 at the edges of the top and bottom sides along the length direction and cogs 231 and through holes 100 at the edges of the two sides, wherein the cogs have a print structure. Figure 14n shows that the suture contains cogs at the edges of the top and bottom sides. 230 and a new protruding cog 232 and a through hole 100 are formed by cutting both sides along the length of the suture, wherein the cogs are arranged in the same direction. Figure 14o illustrates that the suture includes cogs 230 at the edges of the top and bottom sides and cogs 232 and through holes 100 that are newly formed by cutting the sides along the length of the suture, wherein The cogs have a printed structure. New cogs 232 formed by cutting the side edges as shown in Figs. 14n and 14o may also be formed at the edges of the suture. Although a new cog can be formed by cutting the two sides, it is also possible to form a new cog by attaching the cogs to the sides of the suture having a quadrangular cross section, the horizontal length of the suture being The sides of the suture are of equal height. However, instead of forming such a suture by means of attachment, the formation of a new cog by cutting means will contribute to the firmness and stability of the suture and provide a better pulling effect. Figure 14p illustrates that the suture includes cogs 230 at the edges of the top and bottom sides, and cogs 232 that are newly formed by cutting the sides along the length of the suture, by further embedding the same The teeth are cut to be more sharp to form new cogs 233 and through holes 100, wherein the cogs are arranged in the same direction. Figure 14q illustrates that the suture includes cogs 230 at the edges of the top and bottom sides, and cogs 232 that are newly formed by cutting the sides along the length of the suture, by further embedding the same The teeth are cut to be more sharp to form new cogs 233 and through holes 100, wherein the cogs have a printed structure. By sewing the cogs of the sutures of the 14th and 14th figures into sharper shapes, the sutures of the 14th and 14thth drawings are prepared, so that the fixing force and the pulling effect of the suture can be maximized. The cogs described above can also be applied at all edges of the suture.

14r to 14u illustrate a suture having a hexagonal cross section in which both ends in the longitudinal direction are concavely curved to sharpen the end. Figure 14r illustrates that the suture includes cogs 230 and through holes 100 at the edges of the top and bottom sides, wherein the cogs are configured in the same direction. The sutures as shown in Figures 14n through 14q can be made by cutting the two sides of the suture. Figure 14s illustrates that the suture includes cogs 230 and through holes 100 at the edges of the top and bottom sides, wherein the cogs have a printed configuration. Figure 14t illustrates that the suture includes cogs 230 at the edges of the top and bottom sides, cogs 231 at the edges of the two sides along the length, and through holes 100, wherein the cogs are configured the same way. Figure 14u illustrates that the suture includes cogs 230 at the edges of the top and bottom sides, cogs 231 at the edges of the two sides along the length direction, and through holes 100, wherein the cogs have a print structure. In the 14th to 14thth drawings, the cogs 231 located at the edges of the both side edges in the longitudinal direction can be formed by cutting or engraving the edges of the both side edges.

Figures 14v and 14w illustrate perspective views of sutures having cross sections as shown in Fig. 13c. It may be inevitable to form a cross section with a convexly treated side and a rounded end during the process. Figure 14v illustrates that the suture includes cogs 230 at both ends of the top and bottom sides, cogs 231 at the two sides along the length direction, and through holes 100, wherein the cogs are configured to be the same direction. Figure 14w illustrates that the suture includes cogs 230 at both ends of the top and bottom sides, cogs 231 at the two sides along the length direction, and through holes 100, wherein the cogs have a printed structure .

15a to 15b illustrate stitches comprising cogs having two printed structures, according to an exemplary embodiment of the present invention. Figure 15a illustrates that the suture includes cogs 230 and through holes 100 at the edges of the suture, and Figure 15b illustrates that the sutures include cogs 230 at the edges of the sutures, Cogs 231 and through holes 100 at the sides. The printed structures shown in these figures can also be applied to the stitches of other exemplary embodiments of the present invention, and the stitches can include cogs having two or more such printed structures.

Figures 16a through 16f illustrate the position or arrangement of one or more cogs 240 included in the suture 10 of the present invention comprising one or more through holes 100. In the printing structure illustrated in Fig. 16a, the cogs 240 are disposed to face each other with respect to the center of the length of the sheet. In the printing structure illustrated in Fig. 16b, the cogs 240 are arranged so as not to face each other. In the configuration illustrated in Fig. 16c, the cogs 240 positioned on one side face and the cogs positioned on the other side face in opposite directions. In the printed structure illustrated in Fig. 16d, the cogs 240 positioned on one side and the cogs positioned on the other side face in opposite directions. In the configuration illustrated in Fig. 16e, the cogs are at the top and bottom sides along the length direction, and the cogs 240 on each side face in opposite directions. Figure 16f is a perspective view of a sheet having a rectangular cross-section with cogs 240 at the edges, and the cogs 240 on the top side and the cogs on the bottom side are arranged in opposite directions .

Figures 17a through 17g illustrate longitudinal cross-sections of one or more cogs included in the suture 10 of the present invention comprising one or more through holes 100. Figure 17a illustrates a longitudinal section of a suture containing cogs 250 having narrow and curved ends. Figure 17b illustrates a longitudinal section of a suture containing cogs 251 having a bent and hooked end. Figure 17c illustrates a longitudinal section of a suture containing cogs 252 having a rectangular shape. Figure 17d illustrates a longitudinal section of a suture containing cogs 253 having the shape of a parallelogram. Figure 17e illustrates a longitudinal section of a suture containing cogs 254 having a triangular shape. Figure 17f illustrates a longitudinal section of a suture containing cogs 255 having a curved and curved end. Figure 17g illustrates a longitudinal section of a suture containing cogs 256 having the shape of a deformed polygon.

10‧‧‧ stitching

100‧‧‧through hole

Claims (30)

A suture comprising: one or more through holes enabling cells of nearby tissue to grow through the one or more through holes to induce tissue formation and adhesion between skin layers, and the seam The wire has a sheet shape whose length is longer than the width. The suture of claim 1, wherein the through hole is a mesh opening. The suture of claim 2, wherein a horizontal side or a vertical side of the mesh opening forms an acute or right angle with respect to a width direction of the suture. The suture of claim 1, wherein the suture has a polygonal, deformed polygonal, circular, elliptical, deformed elliptical or dumbbell shaped cross section. The suture of claim 1, wherein the suture further comprises one or more nodules. The suture according to claim 1, wherein the suture is thicker than a center at both side edges in the width direction. The suture according to claim 6, wherein the suture has a tubular shape along both sides of one of the longitudinal directions of the sheet. The suture of claim 1, wherein the through hole has an average size of 0.01 mm to 4 mm. The suture of claim 1, wherein the suture has a width of from 0.5 mm to 10 mm. The suture of claim 1, wherein the suture has a thickness of from 0.1 mm to 5 mm. The suture according to claim 1, further comprising one or more latches at an end along one of the lengths of the suture. The suture according to claim 1, wherein the through hole has a shape of a polygon, a deformed polygon, a circle, an ellipse or a deformed ellipse. The suture according to claim 1, wherein the suture portion or the whole comprises: one or more biodegradable polymers selected from the group consisting of polyglycolic acid (PGA), hyaluronic acid (HA), Polylactic acid (PLA), lactic acid-glycolic acid copolymer (PLGA) and polydioxanone (PDS); one or more biodegradable polymers selected from the group consisting of polyethylene, Polypropylene, poly(propylethylene), nylon (nylon), polyfluorene oxide and Teflon; or a combination of the above polymers. The suture according to claim 2, wherein a mesh portion perpendicular to a longitudinal direction of the sheet comprises a highly elastic material having a high elastic material An elastic modulus of 300 MPa or more, and a mesh portion parallel to the longitudinal direction of the sheet, comprise a low elastic material having a modulus of elasticity of 200 MPa or less. The suture of claim 14, wherein the high elastic material is Teflon, and the low elastic material is polypropylene or nylon. The suture of claim 1 to claim 15, wherein the suture further comprises one or more cogs. The suture of claim 16, wherein when the cross section is a polygon, the cog is located at one or more vertices of the polygon. The suture of claim 17, wherein the cross section is square or rectangular. The suture of claim 16, wherein the cogs are located at a top side and a bottom side along a length of the sheet. The suture according to claim 19, wherein the cog is located at an edge of the top side and the bottom side along the length direction of the sheet. The suture of claim 20, wherein the cog at the top side pulls the subcutaneous fat layer, and the cog at the bottom side pulls the fascia layer. The suture of claim 20, wherein the cog is formed by engraving or cutting the edge of the suture. The suture of claim 16, wherein the cog has one or more printed structures. The suture of claim 16, wherein the cog has a sharp, hooked or polygonal end. A suture according to claim 16, wherein a cog at one side of the sheet and a cog at an opposite side of the sheet are disposed in the same or opposite directions. The suture of claim 16, wherein the suture is integrally formed. A kit comprising a suture as claimed in claim 16 and a needle. The kit of claim 27, wherein the kit further comprises an adhesive device attachable to the fascia. The kit of claim 28, wherein the adherent attachable to the fascia is a mesh, gauze or sheet. The kit of claim 27, the kit further comprising a manual, This specification describes a method of using the suture.